ARHGEF11 Antibody Cat. No.: 58-813

ARHGEF11 Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

HOMOLOGY: Predicted species reactivity based on immunogen sequence: Rat

This ARHGEF11 antibody is generated from rabbits immunized with a KLH conjugated IMMUNOGEN: synthetic peptide between 605-632 amino acids from the Central region of human ARHGEF11.

TESTED APPLICATIONS: WB

APPLICATIONS: For WB starting dilution is: 1:1000

PREDICTED MOLECULAR 168 kDa WEIGHT:

Properties

This antibody is purified through a A column, followed by peptide affinity PURIFICATION: purification.

CLONALITY: Polyclonal

ISOTYPE: Rabbit Ig

October 3, 2021 1 https://www.prosci-inc.com/arhgef11-antibody-58-813.html CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.

CONCENTRATION: batch dependent

Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Info

OFFICIAL SYMBOL: ARHGEF11

ALTERNATE NAMES: Rho exchange factor 11, PDZ-RhoGEF, ARHGEF11, KIAA0380

ACCESSION NO.: O15085

GENE ID: 9826

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G and stimulate Rho-dependent signals. A similar BACKGROUND: protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.

REFERENCES: 1) Akiyama, K., et al. J. Hum. Genet. (2010) In press :

2) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

3) Ying, Z., et al. Arterioscler. Thromb. Vasc. Biol. 29(10):1657-1663(2009)

4) Banerjee, J., et al. Biochemistry 48(33):8032-8043(2009)

ANTIBODIES FOR RESEARCH USE ONLY.

For additional information, visit ProSci's Terms & Conditions Page.

October 3, 2021 2 https://www.prosci-inc.com/arhgef11-antibody-58-813.html