Anti-TADA2A monoclonal antibody (DCABH- 201560) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description Many DNA-binding transcriptional activator enhance the initiation rate of RNA polymerase II-mediated transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of some of these variants has not been determined.

Immunogen A synthetic peptide of human TADA2L is used for rabbit immunization.

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Purification Protein A

Conjugate Unconjugated

Applications WB, ELISA

Size 1 mg

Buffer In 1x PBS, pH 7.4

Preservative None

Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

GENE INFORMATION

Gene Name TADA2A transcriptional adaptor 2A [ Homo sapiens (human) ]

Official Symbol TADA2A

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Synonyms TADA2A; transcriptional adaptor 2A; ADA2; ADA2A; KL04P; hADA2; TADA2L; transcriptional adapter 2-alpha; ADA2-like protein; transcriptional adaptor 2 alpha;

Entrez Gene ID 6871

Protein Refseq NP_001159577

UniProt ID A0A024R0Y4

Chromosome Location 17q12-q21

Pathway Chromatin modifying enzymes; Chromatin organization; HATs acetylate histones;

Function DNA binding; chromatin binding; contributes_to histone acetyltransferase activity; sequence- specific DNA binding transcription factor activity; transcription cofactor activity; zinc ion binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved