Anti-TADA2A monoclonal antibody (DCABH- 201560) This product is for research use only and is not intended for diagnostic use.
PRODUCT INFORMATION
Antigen Description Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of some of these variants has not been determined.
Immunogen A synthetic peptide of human TADA2L is used for rabbit immunization.
Isotype IgG
Source/Host Rabbit
Species Reactivity Human
Purification Protein A
Conjugate Unconjugated
Applications WB, ELISA
Size 1 mg
Buffer In 1x PBS, pH 7.4
Preservative None
Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
GENE INFORMATION
Gene Name TADA2A transcriptional adaptor 2A [ Homo sapiens (human) ]
Official Symbol TADA2A
45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]
Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Synonyms TADA2A; transcriptional adaptor 2A; ADA2; ADA2A; KL04P; hADA2; TADA2L; transcriptional adapter 2-alpha; ADA2-like protein; transcriptional adaptor 2 alpha;
Entrez Gene ID 6871
Protein Refseq NP_001159577
UniProt ID A0A024R0Y4
Chromosome Location 17q12-q21
Pathway Chromatin modifying enzymes; Chromatin organization; HATs acetylate histones;
Function DNA binding; chromatin binding; contributes_to histone acetyltransferase activity; sequence- specific DNA binding transcription factor activity; transcription cofactor activity; zinc ion binding;
45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]
Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved