Nutrition in Pregnancy

Total Page:16

File Type:pdf, Size:1020Kb

Nutrition in Pregnancy nutrients Volume 2 Nutrition in Pregnancy Edited by Janna L. Morrison and Timothy R.H. Regnault Printed Edition of the Special Issue Published in Nutrients www.mdpi.com/journal/nutrients Janna L. Morrison and Timothy R.H. Regnault (Eds.) Nutrition in Pregnancy Volume II This book is a reprint of the Special Issue that appeared in the online, open access journal, Nutrients (ISSN 2072-6643) from 2014–2016, available at: http://www.mdpi.com/journal/nutrients/special_issues/nutrition-pregnancy Guest Editors Janna L. Morrison Professor, School of Pharmacy and Medical Sciences University of South Australia Australia Timothy R.H. Regnault Associate Professor, Departments of Obstetrics and Gynaecology/Physiology and Pharmacology Scientist, Children's Health Research Institute Western University Canada Editorial Office MDPI AG St. Alban-Anlage 66 Basel, Switzerland Publisher Assistant Editor Shu-Kun Lin Xiaocen Zhang 1. Edition 2017 MDPI • Basel • Beijing • Wuhan • Barcelona • Belgrade ISBN 978-3-03842-368-3 (Hbk) Vol. 2 ISBN 978-3-03842-308-9 (Hbk) Vol. 1-2 ISBN 978-3-03842-369-0 (PDF) Vol. 2 ISBN 978-3-03842-309-6 (PDF) Vol. 1-2 Articles in this volume are Open Access and distributed under the Creative Commons Attribution license (CC BY), which allows users to download, copy and build upon published articles even for commercial purposes, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. The book taken as a whole is © 2017 MDPI, Basel, Switzerland, distributed under the terms and conditions of the Creative Commons by Attribution (CC BY-NC-ND) license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Table of Contents List of Contributors ......................................................................................................... VII About the Guest Editors ................................................................................................ XIII Preface to “Nutrition in Pregnancy”............................................................................. XV Section 1: Micronutrients and Diet Composition during Pregnancy Jessica A. Grieger and Vicki L. Clifton A Review of the Impact of Dietary Intakes in Human Pregnancy on Infant Birthweight Reprinted from: Nutrients 2015, 7(1), 153–178 http://www.mdpi.com/2072-6643/7/1/153 ........................................................................ 3 Karla A. Bascuñán, Rodrigo Valenzuela, Rodrigo Chamorro, Alejandra Valencia, Cynthia Barrera, Claudia Puigrredon, Jorge Sandoval and Alfonso Valenzuela Polyunsaturated Fatty Acid Composition of Maternal Diet and Erythrocyte Phospholipid Status in Chilean Pregnant Women Reprinted from: Nutrients 2014, 6(11), 4918–4934 http://www.mdpi.com/2072-6643/6/11/4918 .................................................................. 32 Phoebe Starling, Karen Charlton, Anne T. McMahon and Catherine Lucas Fish Intake during Pregnancy and Foetal Neurodevelopment—A Systematic Review of the Evidence Reprinted from: Nutrients 2015, 7(3), 2001–2014 http://www.mdpi.com/2072-6643/7/3/2001 .................................................................... 49 Ian Darnton-Hill and Uzonna C. Mkparu Micronutrients in Pregnancy in Low- and Middle-Income Countries Reprinted from: Nutrients 2015, 7(3), 1744–1768 http://www.mdpi.com/2072-6643/7/3/1744 .................................................................... 63 III Marta Cuervo, Carmen Sayon-Orea, Susana Santiago and Jose Alfredo Martínez Dietary and Health Profiles of Spanish Women in Preconception, Pregnancy and Lactation Reprinted from: Nutrients 2014, 6(10), 4434–4451 http://www.mdpi.com/2072-6643/6/10/4434 .................................................................. 91 Paul A. Dawson, Aoife Elliott and Francis G. Bowling Sulphate in Pregnancy Reprinted from: Nutrients 2015, 7(3), 1594–1606 http://www.mdpi.com/2072-6643/7/3/1594 .................................................................. 110 Meng Wang, Zhi-Ping Wang, Li-Jie Gao, Hui Yang and Zhong-Tang Zhao Maternal Consumption of Non-Staple Food in the First Trimester and Risk of Neural Tube Defects in Offspring Reprinted from: Nutrients 2015, 7(5), 3067–3077 http://www.mdpi.com/2072-6643/7/5/3067 .................................................................. 124 Antonysunil Adaikalakoteswari, Manu Vatish, Alexander Lawson, Catherine Wood, Kavitha Sivakumar, Philip G. McTernan, Craig Webster, Neil Anderson, Chittaranjan S. Yajnik, Gyanendra Tripathi and Ponnusamy Saravanan Low Maternal Vitamin B12 Status Is Associated with Lower Cord Blood HDL Cholesterol in White Caucasians Living in the UK Reprinted from: Nutrients 2015, 7(4), 2401–2414 http://www.mdpi.com/2072-6643/7/4/2401 .................................................................. 136 Yanli Li, Rufei Gao, Xueqing Liu, Xuemei Chen, Xinggui Liao, Yanqing Geng, Yubin Ding, Yingxiong Wang and Junlin He Folate Deficiency Could Restrain Decidual Angiogenesis in Pregnant Mice Reprinted from: Nutrients 2015, 7(8), 6425–6445 http://www.mdpi.com/2072-6643/7/8/5284 .................................................................. 150 IV Section 2: New Studies of Vitamin D and Its Role in Fetal Development Andrea Olmos-Ortiz, Euclides Avila, Marta Durand-Carbajal and Lorenza Díaz Regulation of Calcitriol Biosynthesis and Activity: Focus on Gestational Vitamin D Deficiency and Adverse Pregnancy Outcomes Reprinted from: Nutrients 2015, 7(1), 443–480 http://www.mdpi.com/2072-6643/7/1/443 .................................................................... 177 Rihwa Choi, Seonwoo Kim, Heejin Yoo, Yoon Young Cho, Sun Wook Kim, Jae Hoon Chung, Soo-young Oh and Soo-Youn Lee High Prevalence of Vitamin D Deficiency in Pregnant Korean Women: The First Trimester and the Winter Season as Risk Factors for Vitamin D Deficiency Reprinted from: Nutrients 2015, 7(5), 3427–3448 http://www.mdpi.com/2072-6643/7/5/3427 .................................................................. 219 Xiaodan Yu, Weiye Wang, Zhenzhen Wei, Fengxiu Ouyang, Lisu Huang, Xia Wang, Yanjun Zhao, Huijuan Zhang and Jun Zhang Vitamin D Status and Related Factors in Newborns in Shanghai, China Reprinted from: Nutrients 2014, 6(12), 5600–5610 http://www.mdpi.com/2072-6643/6/12/5600 ................................................................ 243 Adekunle Dawodu, Barbara Davidson, Jessica G. Woo, Yong-Mei Peng, Guillermo M. Ruiz-Palacios, Maria de Lourdes Guerrero and Ardythe L. Morrow Sun Exposure and Vitamin D Supplementation in Relation to Vitamin D Status of Breastfeeding Mothers and Infants in the Global Exploration of Human Milk Study Reprinted from: Nutrients 2015, 7(2), 1081–1093 http://www.mdpi.com/2072-6643/7/2/1081 .................................................................. 254 V List of Contributors Antonysunil Adaikalakoteswari Warwick Medical School, University of Warwick, Coventry CV2 2DX, UK. Neil Anderson Academic department of Diabetes and Metabolism, George Eliot Hospital, Nuneaton CV10 7DJ, UK. Euclides Avila Department of Reproductive Biology, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Vasco de Quiroga No. 15, Tlalpan 14000, Mexico City, Mexico. Cynthia Barrera Department of Nutrition, Faculty of Medicine, University of Chile, Av. Independencia 1027, Independencia, Santiago 8380453, Chile. Karla A. Bascuñán Department of Nutrition, Faculty of Medicine, University of Chile, Av. Independencia 1027, Independencia, Santiago 8380453, Chile. Michelle L. Blumfield School of Health Sciences, and Priority Research Centre in Physical Activity and Nutrition, Faculty of Health and Medicine, University of Newcastle, Callaghan, New South Wales 2308, Australia. Francis G. Bowling Mater Research Institute, Level 4, Translational Research Institute, University of Queensland, 37 Kent St, TRI, Woolloongabba, QLD 4102, Australia; Mater Children's Hospital, Mater Health Services, South Brisbane, QLD 4101, Australia. Rodrigo Chamorro Department of Nutrition, Faculty of Medicine, University of Chile, Av. Independencia 1027, Independencia, Santiago 8380453, Chile. Karen Charlton School of Medicine, University of Wollongong, NSW 2522, Australia. Xuemei Chen Laboratory of Reproductive Biology, School of Public Health, Chongqing Medical University, Chongqing 400016, China. Yoon Young Cho Division of Endocrinology and Metabolism, Department of Medicine, Thyroid Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-Ro, Gangnam-Gu, Seoul 135-710, Korea. Rihwa Choi Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-Ro, Gangnam-Gu, Seoul 135-710, Korea. Jae Hoon Chung Division of Endocrinology and Metabolism, Department of Medicine, Thyroid Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-Ro, Gangnam-Gu, Seoul 135-710, Korea. VII Vicki L. Clifton Robinson Research Institute, School of Paediatrics and Reproductive Health, Adelaide University, Lyell McEwin Hospital, Haydown Road, Elizabeth Vale, SA 5112, Australia. Marta Cuervo Department of Nutrition, Food Sciences and Physiology, Center for Nutritional Research, University of Navarra, Pamplona 31008, Spain; CIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III (ISCIII), Madrid 28029, Spain. Ian Darnton-Hill The Boden Institute of Obesity, Nutrition, Exercise & Eating Disorders, University of Sydney, NSW 2006, Australia; The Friedman School of Nutrition Science and Policy,
Recommended publications
  • Department of Obstetrics and Gynecology
    97 21 1 15,000 240 20 2011 21 30 24 115 80 30 770 UT SOUTHWESTERN 424 2,200 Department of Obstetrics and Gynecology 15 1974 15 1 314,000 NUMBERS2011 DISTINGUISH US PEOPLE75 SET US APART 71,299 14,000 240 3.8 600,000 10 17 770 3 1943 97 50 12 22,900 4 800 5,894 200 1.3 10 0 10,000 1 24 6,500 Numbers Distinguish Us People Set Us Apart Dear Friends, I am proud—and humbled—to introduce you to the Department of Obstetrics and Gynecology at UT Southwestern Medical Center. For more than 50 years, our department has been acknowledged for its contributions to women’s health care— both in obstetrics and gynecology. Our mission has remained unchanged since the department’s founding in 1943. Daily we strive for excellence in patient care, teaching, and research. In the clinical care realm, we provide comprehensive services in dual arenas—a private practice through the UT Southwestern Medical Center University Hospitals and Clinics and a public practice at Parkland Health and Hospital System. This blend not only maximizes our services throughout different segments of the community in which we live and work, but also provides an invigorating environment for our students, residents, fellows, and faculty. On the educational front, our faculty members are recognized as the authors of three major OB/GYN textbooks—Williams Obstetrics, Williams Gynecology, and Essential Reproductive Medicine. They are also responsible for the largest obstetrics and gynecology training program in the nation, with a combined total of 100 available residency positions in Dallas and Austin.
    [Show full text]
  • Nutrition in Andrology, Gynaecology and Obstetrics
    Appendix No. 2 to the procedure of development and periodical review of syllabuses Nutrition in Andrology, Gynaecology and Obstetrics 1. Imprint Faculty name: English Division Syllabus (field of study, level and educational profile, form of studies, Medicine, 1st level studies, practical profile, full time e.g., Public Health, 1st level studies, practical profile, full time): Academic year: 2019/2020 Nutrition in Andrology, Gynaecology and Module/subject name: Obstetrics Subject code (from the Pensum system): Educational units: Department of Social Medicine and Public Health Head of the unit/s: Dr hab. n. med. Aneta Nitsch - Osuch Study year (the year during which the 1st-6th respective subject is taught): Study semester (the semester during which the respective subject is Winter and Summer semesters taught): Module/subject type (basic, corresponding to the field of study, Optional optional): Teachers (names and surnames and Anna Jagielska, MD degrees of all academic teachers of Aleksandra Kozłowska, BSc respective subjects): ERASMUS YES/NO (Is the subject available for students under the YES ERASMUS programme?): A person responsible for the syllabus (a person to which all comments to Anna Jagielska, MD the syllabus should be reported) Number of ECTS credits: 2 Page 1 of 4 Appendix No. 2 to the procedure of development and periodical review of syllabuses 2. Educational goals and aims The aim of the course is to provide students with: 1. The principles of nutrition during adolescence, adulthood and eldery. 2. The relationship between nutrition and fertility, fetal status and communicable diseases in the adults life. 3. Basics of dietary advices for men and women in the reproductive years.
    [Show full text]
  • Archives of Women's Health & Gynecology
    Archives of Women’s Health & Gynecology doi: 10.39127/2677-7124/AWHG:1000103 Tawfik W. Arch Women Heal Gyn: 103. Research Article Clinical Outcomes of Laparoscopic Repair of Paravaginal Defects Waleed Tawfik* Department of Obstetrics and Gynecology, Faculty of Medicine, Benha University, Benha, Egypt. *Corresponding author: Waleed Tawfik: Lecturer of Obstetrics and Gynecology, Faculty of Medicine, Benha University, Benha, Egypt. Citation: Tawfik W (2020) Clinical Outcomes of Laparoscopic Repair of Paravaginal Defects. Arch Women Heal Gyn: AWHG-103. Received Date: 31 March, 2020; Accepted Date: 03 April, 2020; Published Date: 08 April, 2020 Abstract In the era of minimally invasive surgeries, laparoscopic approach has been adopted in many surgical procedures as a successful alternative. Laparoscopic paravaginal repair is a good approach for surgical treatment of lateral type cystoceles. This prospective study was done to investigate whether laparoscopic paravaginal repair might be a reasonable alternative to open or vaginal routes in terms of success rate, operative and postoperative outcomes. Fifty patients with clinically diagnosed paravaginal defect were included in this study. The overall success rate in our study was 88 % after one year according to prolapse staging. This is nearly comparable to the results of most studies. Dividing the overall outcome into favorable and unfavorable, we reported that the unfavorable outcome was 22%. Unfavorable outcome includes cases of recurrence, persistent symptoms or appearance of new complaints. Conclusion: Although laparoscopic paravaginal repair offers an alternative method with shorter hospital stay, less postoperative pain and quicker recovery, but it still has its drawbacks. It needs long learning curve and has prolonged operative time.
    [Show full text]
  • Structured Measurement Error in Nutritional Epidemiology 3 1 = F 60 Ki2 J Kij
    JASA jasa v.2004/12/09 Prn:26/10/2006; 10:42 F:jasaap05194r.tex; (Diana) p. 1 Structured Measurement Error in Nutritional 1 Epidemiology: Applications in the Pregnancy, 60 2 61 3 Infection, and Nutrition (PIN) Study 62 4 63 5 Brent A. JOHNSON,AmyH.HERRING, Joseph G. IBRAHIM, and Anna Maria SIEGA-RIZ 64 6 65 7 66 8 Preterm birth, defined as delivery before 37 completed weeks’ gestation, is a leading cause of infant morbidity and mortality. Identifying 67 factors related to preterm delivery is an important goal of public health professionals who wish to identify etiologic pathways to target 9 68 for prevention. Validation studies are often conducted in nutritional epidemiology in order to study measurement error in instruments that 10 are generally less invasive or less expensive than “gold standard” instruments. Data from such studies are then used in adjusting estimates 69 11 based on the full study sample. However, measurement error in nutritional epidemiology has recently been shown to be complicated 70 12 by correlated error structures in the study-wide and validation instruments. Investigators of a study of preterm birth and dietary intake 71 13 designed a validation study to assess measurement error in a food frequency questionnaire (FFQ) administered during pregnancy and with 72 the secondary goal of assessing whether a single administration of the FFQ could be used to describe intake over the relatively short 14 73 pregnancy period, in which energy intake typically increases. Here, we describe a likelihood-based method via Markov chain Monte Carlo 15 to estimate the regression coefficients in a generalized linear model relating preterm birth to covariates, where one of the covariates is 74 16 measured with error and the multivariate measurement error model has correlated errors among contemporaneous instruments (i.e., FFQs, 75 17 24-hour recalls, and biomarkers).
    [Show full text]
  • Andrology Lab Booklet
    or Reprod er f uc nt ti e ve C M n a e c d i i r c e i Andrology Center and n m e A C e 3 9 n 9 tr 1 um t. E Es Reproductive Tissue Bank xcellentiae Who We Are What We Offer The Andrology Center and Reproductive Tissue Bank - The Andrology Center and Reproductive Tissue a section of the Glickman Urological & Kidney Institute Bank’s specialized laboratory offers a wide variety at Cleveland Clinic - provides specialized tests and of comprehensive tests and the latest technology services to evaluate male infertility. Our laboratory to meet patient needs. The Andrology Center offers offers referring physicians and patient’s quantifiable both research and clinical services. Our laboratory results using the latest state-of-the art technology. uses the latest World Health Organization (WHO, We are located in the Building X, which is part of the Fifth Edition, 2010) guidelines and reference ranges Downtown Main campus. in the evaluation of semen samples. Additionally, our laboratory’s Therapeutic Sperm Banking As part of the American Center for Reproductive program provides a complete fertility preservation Medicine, the Andrology Center and Reproductive service including a reliable system for the long-term Tissue Bank is staffed with highly qualified and preservation of human semen, epididymal aspirate experienced laboratory technologists who are well and testicular tissue. trained in fertility testing and certified by the American Society of Clinical Pathologists (ASCP). Our laboratory is certified by the Clinical Laboratory Improvement Table of Contents Amendments (CLIA) and the Department of Health and Human Services.
    [Show full text]
  • Surgical Techniques
    SURGICAL TECHNIQUES ■ BY DEE E. FENNER, MD, YVONNE HSU, MD, and DANIEL M. MORGAN, MD Anterior vaginal wall prolapse: The challenge of cystocele repair What’s the best strategy? Repairs often fail and the literature is inconclusive. Three experts analyze what we can learn from the limited studies to date, and offer tips on technique. sk a pelvic reconstructive surgeon to above the hymen, since the patient rarely name the most difficult challenge, reports symptoms in these cases. Aand the answer is likely to be anteri- Another challenge involves the use of or vaginal wall prolapse. The reason: The allografts or xenografts, which have not anterior wall usually is the leading edge of undergone sufficient study to determine their prolapse and the most common site of relax- long-term benefit or risks in comparison with ation or failure following reconstructive sur- traditional repairs. gery. This appears to hold true regardless of This article reviews anatomy of the ante- surgical route or technique. rior vaginal wall and its supports, as well as Short-term success rates of anterior wall surgical technique and outcomes. repairs appear promising, but long-term out- comes are not as encouraging. Success usually Why the anterior wall is claimed as long as the anterior wall is kept is more susceptible to prolapse ne theory is that, in comparison with the KEY POINTS Oposterior compartment, the anterior ■ At this time, the traditional anterior colporrhaphy wall is not as well supported by the levator with attention to apical suspension remains the plate, which counters the effects of gravity gold standard.
    [Show full text]
  • NUTR 305: NUTRITIONAL EPIDEMIOLOGY Fall 2016 Course
    NUTR 305: NUTRITIONAL EPIDEMIOLOGY Fall 2016 Course Syllabus Time and location of the course: Tuesdays 1:30-3:00PM Fridays 8:45-10:15AM Location: Jaharis 155 (Except practicum #1: September 30th in Sacker 514 and practicum #2: October 14th in Jaharis 156) Instructor : Fang Fang Zhang, MD, PhD Assistant Professor, Friedman School of Nutrition Science and Policy 150 Harrison Ave, Boston, MA 02111 Email : [email protected] | Phone : 617-636-3704 Teaching Assistants: Danielle Haslam, MA MS Ph.D. Candidate, Nutritional Epidemiology Friedman School of Nutrition Science and Policy Email : [email protected] Mengxi Du MS/MPH Candidate Tufts University School of Medicine Friedman School of Nutrition Science and Policy Email : [email protected] Office Hours: Email anytime to set up an appointment Tufts Graduate Credit: 1.0 Prerequisites for taking this course: Required prerequisites for this course are the following: 1) Introductory Human Nutrition (e.g., NUTR 201 or 202) 2) Introductory Epidemiology (e.g., NUTR 204 or MPH 201) 3) Biostatistics (e.g., NUTR 209/309 A&B or MPH 205) Course Description: This course is designed for graduate students who are interested in conducting or better interpreting epidemiological studies relating diet and nutritional status to disease and health. There is an increasing awareness that various aspects of diet and nutrition may be important contributing factors in chronic disease. There are many important problems, however, in the implementation and interpretation of these studies. The purpose of this course is to examine methodologies used in nutritional epidemiological studies, and to review the current state of knowledge regarding diet and other nutritional indicators as etiologic factors in disease.
    [Show full text]
  • Caring for Yourself During Pregnancy and Beyond
    Caring for Yourself During Pregnancy and Beyond Obstetrics Services • A National Center of Excellence in Women’s Health Welcome Dear Patient, Thank you for choosing UCSF Women’s Health Obstetrics Services for your pregnancy care. It’s an exciting time and we are pleased to be able to partner with you on your path towards delivering a healthy baby. Our multidisciplinary team is committed to providing you with compassionate and expert care so that you enjoy a safe and rewarding experience. This patient guide was created to provide you with a resource that explains the many services we offer and what you may expect along your journey. Make sure you refer to it often. If you have questions along the way, please do not hesitate to ask us. Sincerely, Your Team UCSF Women’s Health Obstetrics Services Obstetrics Services • A National Center of Excellence in Women’s Health Our Obstetrics Providers Detailed biographies for each provider are available on our web site at www.ucsfhealth.org/clinics/obstetrics_services/index.html. Choose Maternal-Fetal Medicine under the Divisions heading (on the right side of the web page). Certified Nurse-Midwives and Nurse Practitioners Kathleen Belzer, CNM Judith Bishop, CNM Danielle Briggs, NP Melinda Fowler, CNM Kate Frometa, CNM Sasha Yamnik, CNM Vanessa Tilp, CNM Sharon Wiener, CNM Laura Weil, CNM General Obstetrics and Gynecology Meg Autry, MD Erin Dainty, MD Elena Gates, MD Anna Glezer, MD Andrea Jackson, MD Thoa Ha, MD Robyn Lamar, MD Felicia Lester, MD Tami Rowen, MD Sara Whetstone, MD Obstetrics Services • A National Center of Excellence in Women’s Health Our Obstetrics Providers Detailed biographies for each provider are available on our web site at www.ucsfhealth.org/clinics/obstetrics_services/index.html.
    [Show full text]
  • Pediatric & Adolescent Gynecology – a How to Approach (Didactic)
    Pediatric & Adolescent Gynecology – A How To Approach (Didactic) PROGRAM CHAIR Joseph S. Sanfi lippo, MD Heather Appelbaum, MD Robert K. Zurawin, MD Sponsored by AAGL Advancing Minimally Invasive Gynecology Worldwide Professional Education Information Target Audience Educational activities are developed to meet the needs of surgical gynecologists in practice and in training, as well as, other allied healthcare professionals in the field of gynecology. Accreditation AAGL is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AAGL designates this live activity for a maximum of 3.75 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. DISCLOSURE OF RELEVANT FINANCIAL RELATIONSHIPS As a provider accredited by the Accreditation Council for Continuing Medical Education, AAGL must ensure balance, independence, and objectivity in all CME activities to promote improvements in health care and not proprietary interests of a commercial interest. The provider controls all decisions related to identification of CME needs, determination of educational objectives, selection and presentation of content, selection of all persons and organizations that will be in a position to control the content, selection of educational methods, and evaluation of the activity. Course chairs, planning committee members, presenters, authors, moderators, panel members, and others in a position to control the content of this activity are required to disclose relevant financial relationships with commercial interests related to the subject matter of this educational activity. Learners are able to assess the potential for commercial bias in information when complete disclosure, resolution of conflicts of interest, and acknowledgment of commercial support are provided prior to the activity.
    [Show full text]
  • Design of Clinical Trials Evaluating Dietary Interventions in Patients with Functional Gastrointestinal Disorders
    748 ROME FOUNDATION WORKING GROUP nature publishing group Design of Clinical Trials Evaluating Dietary Interventions in Patients With Functional Gastrointestinal Disorders Chu K. Yao , BND (Hons)1 , P e t e r R . G i b s o n , M D , F R A C P1 a n d S u s a n J . S h e p h e r d , P h D , M N D , B A p p S c i 2 Clear guiding principles for the design and conduct of dietary intervention trials in functional gastrointestinal disorders (FGID) are lacking. This narrative review examines the specifi c challenges associated with the design and reporting in dietary intervention trials. Dietary intervention trials need to address the collinearity between food, nutrients, and bioactive components that obscure the relationship between food and their effects in the gut. Randomized, double-blinded, placebo-controlled studies remain the gold standard for dietary trials, but are limited by diffi culties in adequate masking of study food or inappropriate choice of placebo food / diets. Provision of study diets as the preferred delivery method can somewhat address these limitations, although allowing good adherence compared with education-based dietary interventions. Issues associated with participant expectancies and dietary behaviors can alter the true effectiveness of a diet. In addition, failure to adjust for or report baseline intake of nutrients of interest can reduce their magnitude of benefi t. Bias in subjective reports and choice of measurement tools can preclude accurate assessment of food-intake data. In the design of elimination and rechallenge studies, suffi cient time period and adequate exclusion of dietary triggers are essential to ensure symptoms are well-controlled before rechallenging.
    [Show full text]
  • Female Circumcision: the History, the Current Prevalence and The
    Female Circumcision: The History, the Current Prevalence and the Approach to a Patient April 2017 Jewel Llamas Introduction together, covering the urethra and vagina and leaving small opening for urination and Female circumcision, also known as female genital menstruation (infibulation) mutilation (FGM) or female genital cutting (FGC), is Type 4: All other harmful procedures to the practiced in many countries spanning parts of Africa, the female genitalia for non-medical purposes Middle East and Southeast Asia. Over 100 million including pricking, piercing, incising, scraping women and young girls living today have experienced and cauterizing some form of FGM with millions more being affected annually. With the world becoming a smaller and smaller place via media, travel and international migration, widespread awareness (beyond the regions of its practice) of the history and beliefs that perpetuate this tradition is essential. This paper offers a guide to help practitioners understand the terminology, classifications, origin, proposed purposes, current distribution and prevalence of FGM, closing with recommendations for obtaining a history from and conducting a pelvic exam on this patient population. Terminology and Classifications The practice of female genital alterations has been referred to by many different names. The United Nations conducted their earliest studies on these practices using However, this terminology is not accepted by all, an anthropological approach, adopting the term “female especially by those who originate from areas where these circumcision,” which the World Health Organization practices occur. In one ethnographic study conducted in adopted as well. However, many believed this term Sudan, participants often found the term “mutilation” euthanized and “normalized” the practice, making it offensive, suggesting “intentional harm” and “evil comparable to widely accepted male circumcisions.
    [Show full text]
  • OB/GYN) and Pediatric Clinics
    ASPR TRACIE Technical Assistance Request Request Receipt Date (by ASPR TRACIE): 30 September 2019 Response Date: 1 October 2019 Type of TA Request: Standard Request: The requestor asked if ASPR TRACIE had any emergency operations plans (EOPs) and other resources specific to obstetrics/ gynecology (OB/GYN) and pediatric clinics. Response: The ASPR TRACIE Team reviewed exiting Topic Collections; namely the following: • Access and Functional Needs o In particular, please review the Population-Specific Resources: Women and Gender Issues section • Ambulatory Care and Federally Qualified Health Centers (FQHC) • Healthcare Facility Evacuation / Sheltering o In particular, please review the Special Populations: Pediatric, NICU, and OB/GYN-Related Resources section • Pediatric We would also like to provide the following TA response that may be helpful to the requestor: • Evacuation Resources for Neonatal Intensive Care Units (NICU) and High-Risk Obstetrics (OB) Units. This ASPR TRACIE TA provides links to resources specific to the evacuation of neonatal and pediatric intensive care units and high-risk obstetric units. Section I in this document includes planning resources specific to OB/GYN and pediatric offices, or other similar healthcare facilities in which the information can be adapted for use by such clinics. I. Planning Resources Related to OB/GYN and Pediatric Clinics American Academy of Pediatrics. (2013). Preparedness Checklist for Pediatric Practices. This document offers checklists and steps that office-based pediatricians or their practice staff can take to improve office preparedness. It allows for advanced preparedness planning that can mitigate risk, ensure financial stability, strengthen the medical home, and help promote the health of children in the community.
    [Show full text]