19Th International Vascular Biology Meeting
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19th International Vascular Biology Meeting Sheraton Boston Hotel - Boston, Massachusetts, USA October 30-November 3, 2016 Preliminary Program Call for Abstracts Organization and Sponsors Abstracts are due July 26, 2016 Early bird registration ends August 15 Hotel reservation deadline is October 8 www.ivbm2016.org Photo courtesy of the Greater Boston Convention & Visitors Bureau Photo courtesy & Boston Convention of the Greater Sponsors and Supporters* Diamond Level Supporter and Host of the Welcome Reception Gold Level Supporter Meet the Professor Supported by: Event Partners Contributors Academic Supporters Silver Level Bronze Level THE DIVISION OF PREVENTIVE MEDICINE BRIGHAM AND WOMEN’S HOSPITAL *Opportunities for sponsors, supporters and exhibitors are still available; contact [email protected] Overview of the Program Opening Plenary Session Sunday evening, October 30 at 6:30pm Inflammation and Atherothrombosis: A Clinical Investigator’s Perspective Paul Ridker, Brigham and Women’s Hospital/Harvard Medical School Targeting Endothelial Cell Metabolism: Principles and Therapeutic Potential Peter Carmeliet, University of Leuven Followed by the Welcome Reception Hosted by Kowa Thematic Sessions Monday, October 31 through Wednesday, November 2 from 8:30am to 6:00pm Diseases • Cells and Vascular Beds • Cellular Processes • Emerging Topics Eye-Opener Sessions for Trainees (Networking Breakfasts) Monday, October 31 through Wednesday, November 2 from 7:30am to 8:15am Meet-the-Professors Breakfasts; Opportunities in Cardiovascular Research: An NIH Perspective, An Industry Perspective and An Editor’s Perspective; and Women in Science Sessions sponsored and co-sponsored by Collaborating Societies Cure HHT European Vascular Biology Organisation Japanese Vascular Biology and Medicine Organization Korean Vascular Science and Medicine Organization Gala at the Isabella Stewart Gardner Museum Tuesday evening, November 1 from 6:30-9:30pm (additional fee for tickets) Closing Plenary Session Thursday morning, November 3 (conference will conclude at 1:00pm) Rethinking the Thrombotic Complications of Atherosclerosis Peter Libby, Brigham and Women’s Hospital/Harvard Medical School Earl P. Benditt Award Lecture: Transcriptional Regulation of Endothelial Cell Plasticity in Health and Disease Elisabetta Dejana, University of Milan, IFOM Judah Folkman Award in Vascular Biology Lecture: The Ups and Downs of Anti-Angiogenic Therapy Gabriele Bergers, University of California, San Francisco Springer Junior Investigator Award Lecture Tuesday Night Gala at To be determined the Isabella Stewart Mechanisms of Vessel Maturation: Closing the Loop Gardner Museum Jan Kitajewski, University of Illinois, Chicago Photo courtesy of the Isabella Stewart Gardner Museum Diseases Atherosclerosis I Matthias Nahrendorf, Massachusetts General Hospital/Harvard Medical School Inflammatory networks in cardiovascular disease Ziad Mallat, University of Cambridge Targeting the immune response in ischemic cardiovascular disease Atherosclerosis II Hyo-Soo Kim, Seoul National University Hospital Mechanism of calcification in atherosclerosis: Role of bone-marrow-derived calcifying progenitors Ira Tabas, Columbia University Defective inflammation resolution in atherosclerosis: Mechanisms and therapeutic implications Atherosclerosis III - Co-sponsored by the Japanese Vascular Biology and Medicine Organization Eicke Latz, University Hospital, University of Bonn Innate immune memory in atherosclerosis Masataka Sata, Tokushima University Graduate School Role of innate immunity in chronic inflammation in arterial wall and adipose tissue Large Vessel Disease Outside the Heart - Co-sponsored by the Japanese Vascular Biology and Medicine Organization Brian Annex, University of Virginia Micro-RNA’s in peripheral arterial disease Ryuichi Morishita, Osaka University Recent progress in molecular medicine on critical limb ischemia: From regenerative medicine to vaccine Neurovascular Disease Anne Joutel, INSERM - University of Paris Novel insight into the pathogenesis of CADASIL Costantino Iadecola, Weill Cornell Medical College Neurovascular dysfunction and cognitive impairment Pulmonary Hypertension Kurt Stenmark, University of Colorado Denver Metabolic reprogramming and inflammation act in concert to control vascular remodeling in hypoxic pulmonary hypertension Evangelos Michelakis, University of Alberta The metabolic basic of vascular disease and pulmonary arterial hypertension Vascular Malformations - Co-sponsored by Cure HHT Miikka Vikkula, de Duve Institute, Université catholique de Louvain Deciphering the heterogeneity of vascular malformations by next generation sequencing Douglas Marchuk, Duke University Cerebral cavernous malformations: From gene discovery to potential therapy Cancer Anna Dimberg, Uppsala University Vascular abnormalization in glioblastoma Gou Young Koh, KAIST Molecular targeting of tumor vasculatures Obesity/Diabetes Kenneth Walsh, Boston University School of Medicine Role of adipokines in obesity-linked vascular disease Ann Marie Schmidt, New York University School of Medicine RAGE & the Formin DIAPH1 & mechanisms of diabetic complications Thrombosis Denisa Wagner, Boston Children’s Hospital, Harvard Medical School Pathological impact of Neutrophil Extracellular Traps (NETs) Jose Lopez, Puget Sound Blood Center Regulation of von Willebrand factor adhesive function Cells and Vascular Beds Endothelial Cells Toren Finkel, NHLBI/NIH Autophagic and metabolic regulation of vascular function Ralf Adams, Max-Planck Institute for Molecular Biomedicine Organ-specific and functional specialization of blood esselsv Smooth Muscle Cells Gary Owens, University of Virginia SMC phenotypic transitions play a key role in the pathogenesis of advanced atherosclerotic lesions Christer Betsholtz, Uppsala University Pericytes in health and disease Stem Cells I - Co-sponsored by the European Vascular Biology Organisation Shahin Rafii, Weill Cornell Medical College Tissue-specific endothelial-derived angiocrine signals in organ regeneration Kristy Red-Horse, Stanford University Origin and patterning of coronary arteries Heart Mark Kahn, University of Pennsylvania Molecular insights into CCM signaling in the endocardium Joyce Bischoff, Boston Children's Hospital/Harvard Medical School Reactivation of endothelial-to-mesenchymal transition as mechanism for mitral valve adaptation Microcirculation David Gutterman, Medical College of Wisconsin Redox regulation of microvascular function in humans William Chilian, Northeast Ohio Medical University Is it time to think big about coronary microvessels? Liver Hellmut Augustin, University of Heidelberg & German Cancer Research Center Angiopoietin/Tie signaling revisited: Conditional mutagenesis reveals novel functions of the Tie receptors Vijay Shah, Mayo Clinic Biology of the hepatic sinusoids Kidney Janos Peti-Peterdi, University of Southern California New mechanism of renal vascular and glomerular remodeling Susan E. Quaggin, Northwestern University High “Tek” solutions for vascular complications of diabetes Eye Richard Lang, Cincinnati Children's Hospital Medical Center Light response pathways in vascular development Xuri Li, Sun Yet-Sen University Novel Functions of VEGF-B in Angiogenesis Brain Jaime Grutzendler, Yale School of Medicine Microvascular mural cell physiology and pathology investigations in the live mouse brain Mark Nelson, University of Vermont Potassium sensing by capillary KIR channels initiates retrograde electrical signaling to regulate cerebral blood flow Lung Eric Schmidt, University of Colorado Denver The pulmonary endothelial glycocalyx: A determinant of lung injury onset and resolution Asrar Malik, University of Illinois College of Medicine Lineage tracing analysis of lung microvessel repair Cellular Processes Development - Co-sponsored by Cure HHT Holger Gerhardt, Max-Delbrueck-Center for Molecular Medicine Functional plasticity in vascular networks - a developmental perspective Victoria Bautch, University of North Carolina at Chapel Hill How blood vessels form in space and time Angiogenesis and Arteriogenesis I - Co-sponsored by the European Vascular Biology Organisation Luisa Iruela-Arispe, University of California, Los Angeles Common and distinct operative mechanisms during vascular growth and sprouting angiogenesis Young-Guen Kwon, Yonsei University New regulators of vascular sprouting and remodeling Angiogenesis and Arteriogenesis II - Co-sponsored by the Japanese Vascular Biology and Medicine Organization Hong Chen, Boston Children's Hospital/Harvard Medical School The role of endocytic adaptor proteins, epsins in vascular biology Nobuyuki Takakura, Osaka University Apelin/APJ system for the vascular maturation Extracellular Matrix Tatiana Byzova, Cleveland Clinic - Lerner Research Institute Integrin-dependent crosstalk between microglia and vasculature Martin A. Schwartz, Yale School of Medicine Fluid shear stress mechanotransduction in vascular health and disease Vascular Remodeling David G. Harrison, Vanderbilt University School of Medicine Immune mechanisms in cardiovascular disease Andrew Baker, University of Glasgow The influence of non-coding RNA on vascular pathophysiology Permeability Lena Claesson-Welsh, Uppsala University Therapeutic targeting of VEGF-regulated vascular permeability Dietmar Vestweber, Max-Planck Institute for Molecular Biomedicine Regulation of endothelial junction integrity Immunity I Tanya N. Mayadas, Brigham & Women's Hospital/Harvard Medical School Leukocyte trafficking in renal