Name: Carlos Alberto Aguilar Salinas Age:56 years Date of birth: November 16, 1961 Place of birth: Mexico City, México Address: Instituto Nacional de Ciencias Médicas y Nutrición, Vasco de Quiroga 15, Mexico City 14000, Mexico Scopus ID: 55989775200 ORCID: http://orcid.org/0000-0001-8517-0241

H index: 53

Abstract Dr. Carlos A. Aguilar Salinas is recognized for his contributions as a researcher, professor and clinician in the study of dyslipidemias and type 2 diabetes in Mexico. He is the founder of the Lipid Clinic and the current coordinator of the research committee at the the Instituto Nacional de Ciencias Medicas y Nutricion (INCMNSZ), Mexico City. His research covers the identification of the main susceptibility genes for type 2 diabetes and dyslipidemias in Mexican mestizos and epidemiological studies that have served to describe the burden of the disease caused by these disorders. He has published 246 articles in indexed journals (Nature, JAMA, Nature genetics, JCEM, among others) and has been tutored 20 PhD students. In addition, Dr Aguilar Salinas has played a leading role in design and implementation of interventions against chronic diseases at regional and national level. He coordinated the position paper against diabetes presented by the Mexican National Academy of Medicine. Dr Aguilar Salinas was President of the Mexican Society of Nutrition and Endocrinology; a collaboration with the Endocrine Society was started during his term. He has served as member of several committes and task forces of international societies (including the Endocrine Society) and research consortia (e.g. Global Alliance of Chronic Diseases and EULAC Health). Currently, he is co-editor of the “Revista de la Asociación Latinomericana de Diabetes” and member of the editorial boards of several prestigious journals. Dr Aguilar Salinas is part of the Diabetes Lancet Commission. He received the National Science Award in 2018.

Grades Title Year Bachelor in Science 1980 MD 1980-1986 Universidad Nacional Autónoma de México. Facultad de Medicina Internal Medicine. 1986-1989 Instituto Nacional de la Nutricion (Board certificate by the Consejo Mexicano de Medicina Interna) Endocrinology. 1989-1991 Instituto Nacional de la Nutricion (Board certificate by the Consejo Mexicano de Endocrinología y Nutrición) Research fellowship. Atherosclerosis and Lipid Research Division. 1992-1994 Washington University.St. Louis, MO USA PhD in medical sciences 2011-2014 Instituto Politécnico Nacional. Mexico City Positions Institution Position Period Facultad de Medicina. Assistant professor 1981-1984 Universidad Nacional Autónoma de México Departamento de Bioquímica Instituto Nacional de Ciencias Medical researcher 1991- Médicas y Nutrición Director of the Lipid Clinic 1994- Vice-head of the Departamento de 1996- Endocrinología y Metabolismo Washington University. School of Visiting professor 2000 Medicine Ethics Committe of the Instituto Coordinator 2012-2013 Nacional de Ciencias Médicas y Nutricion Research Committe of the Coordinator 2013- Instituto Nacional de Ciencias Médicas y Nutricion Metabolic Unit. Instituto Nacional Head 2017- de Ciencias Medicas y Nutricion

Awards and participation in international Committees 1. Member of the Mexican Academy of Medicine 2003-. 2. Member of the Consejo Mexicano de Endocrinología (Vocal 1994-6, Exams director 1996-1998) 3. National researcher by the Sistema Nacional de Investigadores (Level 1 from1997-2003, level 2 from 2003 - 2007, level 3 from 2007- ) 4. Secretary of the Sociedad Mexicana de Nutrición y Endocrinología. 1999. 5. Member of the Ethics Committee of the Instituto Nacional de Ciencias Médicas y Nutrición May 2001- 6. Young investigator award (“Alfonso Rivera”) by the Sociedad Mexicana de Nutrición y Endocrinología 2001. 7. Young investigator award (“Miguel Alemán”) by the Fundación Miguel Alemán 2002 8. President of the Sociedad Mexicana de Nutrición y Endocrinología. 2009. 9. “Miguel Otero” award by the Mexican Health Ministry 2014 (merits as medical researcher) 10. Management committee of the Global Alliance of Chronic Diseases (2015-) 11. Board of the European Union- Latinamerica and the Caribean research consortia (EULAC Health) (2014-) 12. Diabetes Lancet Commission (2016-) 13. National Science Award 2018. Mexican Federal Government

Papers published in indexed journal:357 1. Aguilar CA,Hurtado R. The laboratory control of the oral anticoagulation.Current Concepts Rev Invest Clin 1989:41:371-74 2. Cortes JE, Gamba G, Aguilar CA, Manfrini F, Gonzalez Chon O,Castorena G. El traslado de pacientes en estado crítico. Rev. Invest. Clin. 1992,44:71-76. 3. Aguilar CA, Wong B,Gomez-Perez FJ, Rull JA. Combination daytime chlorpropamide- metformin/bedtime insulin in the treatment of secondary failure in non insulin dependent diabetes mellitus. Rev Invest Clin 1992, 44:371-4 4. Aguilar CA, Reza A, Garcia E, Rull JA. Biguanide Related Lactic Acidosis:Incidence and Risk factors. Arch Med Res 1992:23:19-24. 5. Aguilar CA, PHR Barrett, KG Parhofer, S Young, G Schonfeld. Apoprotein B-100 production is decreased in subjects heterozygotes for truncations of apoprotein B. Arteriosclerosis & Thrombosis 1995: 15 (1): 71-80. 6. Aguilar-Salinas CA, PHR Barrett, J Kelber, J Delmez , G Schonfeld.”Physiologic mechanism of action of lovastatin in nephrotic syndrome”. J Lipid Res 1995; 36 (1): 188-199. 7. Parhofer KG, Barrett PHR, Aguilar-Salinas Ca, Schonfeld G.Positive linear correlation between the length of truncated apolipoprotein B and its secretion rate. Journal of Lipid Research 1996: 37, 844- 852. 8. Lerman I, Aguilar Salinas Carlos A, Gómez Pérez FJ, Rull JA."Acarbose: a drug in search of its real indication Diabetes Care January 1996 ( Letter)19:115 9. Fco J Gómez Pérez, Valles V, Lopez JC, Choza R, Ibarra J, Gonzalez R, Perez O, Rodriguez E, Aguilar CA, Rull JA. Vitamin E modifies neither fructosamine nor HbA1c levels in poorly controlled diabetes. Revista de Investigación Clínica 1996, 48: 421-4 10. Gómez Pérez FJ Choza R, Rios JM, Reza A, Huerta E, Aguilar CA, Rull JA. Nortriptyline Fluphenazine vs carbamazepine in the symptomatic treatment of diabetic neuropathy. Arch Med Res 1996;27:525- 529. 11. Aguilar-Salinas CA, Barrett PHR, Schonfeld G, et al. Description of a kindred with Familial Combined Hyperlipidemia with unusual kinetic abnormalities of the apolipoprotein B containing lipoproteins. Effects of pravastatin therapy. Arteriosclerosis, Thrombosis and Vascular Biology 1997: 17:72-82. 12. Arita-Melzer O, Medina H, Borsotto-Ganem G, Gamboa A, Trejo G, Cardenas S, Aguilar-Salinas CA, Gómez-Pérez FJ. An Ectopic Adrenocorticotropic Hormone Syndrome Caused by a Sacrococcygeal chordoma. Report of a Case with a Slow Progression and Review of the Literature. Endocrine Practice 1998, 4:37-41. 13. Schonfeld G, Aguilar-Salinas CA, Elias N. Role of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase inhibitors (“Statins”) in familial combined hyperlipidemia. Am J Cardiol 1998;81(4 A):43B-46B. 14. Reza A, Aguilar-Salinas Carlos A. Controversias y avances en el tratamiento de las hiperlipidemias. Gaceta Médica Méx 1998;134:253-256 15. Aguilar-Salinas Carlos A, Garcia E, Lerman I, Gómez Pérez FJ, Rull JA. Making things easier is not so easy.: The ADA criteria and the glucose intolerance. Diabetes Care 1998; 21:1027-28. 16. Lerman I, Villa A, Llaca C, Cervantes L, Aguilar –Salinas CA et al. The prevalence of diabetes and associated coronary risk factors in urban and rural older mexican populations. J Am Geriatric Soc 1998:46:1387-95 17. Aguilar-Salinas CA, Barrett H, Schonfeld G. Metabolic modes of action of statins in the hyperlipoproteinemias .Atherosclerosis 1998;141 203-207 18. Francisco J Gómez-Pérez MD,Carlos Alberto Aguilar-Salinas MD,Juan Carlos López-Alvarenga MD PhD, Luz E. Guillen BS, Belia Wong BS,Juan A Rull-Rodrigo MD.Lack of agreement between the World Health Organization category of impaired glucose tolerance and the American Diabetes Association category of impaired fasting glucose Diabetes Care 1998;21:1886-8 19. Lopez JC, Aguilar-Salinas CA, Velasco ML, Arita O, Guillen L, Wong B, Brito G, Mercado V, Gomez FJ, Rull JA. Acarbose vs bedtime NPH insulin in the treatment of secondary failures to sulphonylurea- metformin therapy in NIDDM.. Diabetes Obesity and Metabolism 1999;1:29-35 20. Aguilar CA, Botet JP, Ordovas JM, Talavera G, Guillén LE, Barriguete JA, Leco ME, Gonzalez-Barranco J, Gómez-Pérez FJ, Rull JA. The apolipoprotein E4 allele is not associated with an atherogenic lipid profile in a Native-American population following its traditional lifestyle. Atherosclerosis 1999;142:409-414. 21. Bautista S, Velasco ML, Castellanos R, Centeno E, Guillén L, Lerman I, Aguilar Salinas CA., Gómez Pérez FJ. Diabetes Education and Its Determinants in a Mexican Population. The Diabetes Educator 1999;25:374-381 22. Lerman I, Villa A, Llaca C, Cervantes L, Aguilar CA, Villagra l, Wong B, López JC, Gómez Pérez FJ, Gutierrez LM. The prevalence of obesity and its determinants in urban and rural aging mexican populations. Obesity Research 1999;7:402-4 23. Aguilar-Salinas CA, Francisco J. Gómez Pérez, J. A. Rull. Limitaciones de los criterios de diagnóstico de la diabetes tipo 2 y la intolerancia a la glucosa. Rev Invest Clinica 2000;52:177-184. 24. Aguilar Salinas CA, Rull JA, Garcia E, Zuñiga S, Vazquez C, Palacios A, Frati A, Altamirano E, Herrera M, Rosas J, et al. Consenso Mexicano para la Prevención de las Complicaciones Crónicas de la Diabetes tipo 2. Avalado por la Sociedad Mexicana de Nutrición y Endocrinología, Asociación de Medicina Interna de México y la Sociedad de Nutriología. Revista de Investigación Clínica 2000;52:325-63. 25. Aguilar-Salinas CA, Gómez-Pérez FJ, Posadas-Romero C, Vázquez-Chávez C, Meaney C, Gulías-Herrero A, Guillén LE, Alvarado A, Mendoza E, Romero-Nava LE, Gómez-Díaz RA, Salinas-Orozco S, Moguel R, Novoa G. Efficacy and safety of atorvastatin in hyperlipidemic, type 2 diabetic patients. A 34 week, multicenter, open- label study. Atherosclerosis 2000;152:489-96 26. Aguilar Salinas CA. La obesidad en la pobreza:Un nuevo reto para la salud pública.Revista de Investigación Clinica 2000;52:469-70. 27. Aguilar-Salinas CA, Reyes-Rodríguez E, Ordóñez-Sánchez ML, Arellano Torres M, Ramírez-Jiménez S, Domínguez-López A, Martínez-Francois JR, Velasco-Pérez ML, Alpizar M, García-García E, Gómez- Pérez FJ, Rull JA, Tusié-Luna MT Early-Onset Type 2 Diabetes: Metabolic and Genetic Characterizarion in Mexican Population. J Clin Endoc Metab 2001;86:220-26. 28. Aguilar-Salinas CA, Arita Melzer O, Sauque Reyna L, López A, Velasco Pérez ML, Guillén LE, Gómez Pérez FJ, Rull JA. Effects of estrogen/medrogestone therapy on the apoprotein B containing lipoproteins in postmenopausal women with type 2 diabetes mellitus under satisfactory and non satisfactory glycemic control Israel Med Assoc Journal 2001; 3: 137-143. 29. Aguilar-Salinas CA, Pérez J, Villa A, Llaca-Martinez C, Cervantes- Turrubiatez L, Wong B, Gómez-Pérez FJ, Gutierrez-Robledo LM, Lerman-Garber I. Lipids, Apolipoprotein B and associated coronary risk factors in urban and rural older Mexican populations Metabolism 2001;50:311-18 30. Aguilar-Salinas CA, Fanghänel-Salmón G, Meza E, Montes J, Gulías-Herrero A, Sánchez L, Monterrubio-Flores E, González-Valdez H, Gómez Pérez FJ. Ciprofibrate vs gemfibrozil in the treatment of mixed hyperlipidemias: an open label, multicenter study. Metabolism.2001; 50:729- 33. 31. Aguilar-Salinas CA. Hipercolesterolemia familiar. Revista de Investigacion Clinica 2001;53:254-65. 32. Aguilar-Salinas Carlos A. , Olaiz G,Valles V, Ríos JM, Gómez Pérez FJ, Rull JA, Rojas R, Franco A, Sepúlveda J. High prevalence of low HDL cholesterol concentrations and mixed hyperlipidemia in a Mexican nation wide survey. J Lipid Research 2001;42:1298-307. 33. Aguilar-Salinas CA, Vazquez-Chavez C, Gamboa-Marrufo R, García Soto N, Ríos Gonzalez JJ, Holguín R,Vela S, Ruiz Alvarez F, Mayagoitia S.Prevalence of obesity, diabetes, hypertension and tobacco consumption in an urban adult Mexican population. Arch Med Res 2001;32:446-53. 34. Aguilar-Salinas CA, Arellano A, Villanueva-Sánchez O, Magos G, Guillén -Pineda LE, Rodríguez R, Gómez-Pérez FJ, Effects of Omapatrilat on blood pressure and insulin sensitivity in an animal model of insulin resistance. Blood Pressure 2001:10:164-169 35. Aguilar-Salinas CA, Fanghänel-Salmón G, Meza E, Montes J, Gulías-Herrero A, Sánchez L, Monterrubio-Flores E, González-Valdez H, Gómez Pérez FJ. Ciprofibrate vs gemfibrozil in the treatment of mixed hyperlipidemias: an open label, multicenter study. (letter). Metabolism. 2001; 50:1385-1386 36. Aguilar-Salinas CA, García-García E, Gómez Pérez FJ, Rull JA The healthy women bias and hormone replacement therapy in women with type 2 diabetes (letter) Diabetes Care 2002; 25:246-247. 37. Gómez-Pérez FJ,Aguilar-Salinas CA,Vázquez-Chávez C,Fanghänel-Salmón G, Gallegos-Martínez J,Gómez-Díaz R,Salinas-Orozco S,Chavira-López S,Guillén-Reyes L,Torres-Acosta E,Tamez R,López A, Guillén LE, Cesarman G, Further insight on the hypoglycemic and non-hypoglycemic effects of troglitazone 400 or 600 mg/day: Effects on the VLDL and HDL lipoprotein particle distribution. Metabolism. 2002;51:44-51 38. Aguilar-Salinas CA,Delgado A, Gómez-Pérez FJ. The advantages of using non-HDL cholesterol in the diagnosis and treatment of dislipidemias (letter). Arch Intern Med 2002;162:102-106 39. Del Rincón-Jarero JP,Aguilar-Salinas CA,Guillén-Pineda LE,Gómez Pérez FJ,Rull JA. Lack of agreement between the plasma lipid based criteria and the apoprotein B for the diagnosis of Familial Combined Hyperlipidemia (FCHL) in members of FCHL kindreds. Metabolism 2002;51:218-24 40. Valles V, Aguilar-Salinas CA, Gómez-Pérez FJ, Rojas R, Franco A, Olaiz G, Rull JA, Sepúlveda J Apolipoprotein B and AI distribution in the Mexican urban adults: Results of a Nation-Wide Survey. Metabolism 2002;51:560-568 41. García-García E, Aguilar-Salinas CA, Tusié-Luna MT, Rull-Rodrigo JA. Early onset type 2 diabetes in México. Israel Med Assoc Journal 2002;4:444-8 42. Aguilar-Salinas CA, Díaz-Polanco A, Quintana E, Macias M, Arellano A, Ramírez E, Ordóñez ML, Velásquez-Alva C, Gómez Pérez FJ, Alberú J and Correa-Rotter R: Genetic factors play an important role in the pathogenesis of hyperlipidemia post-transplantation. Am J Kidney Diseases 2002;40:169- 177. 43. Aguilar-Salinas CA, Rojas R, Gómez-Pérez FJ, Valles V, Franco A, Olaiz G, Sepúlveda J, Rull JA. Características de los casos con dislipidemias mixtas en un estudio de población: resultados de la Encuesta nacional de Enfermedad Crónicas. Salud Publica de México 2002;44:546-553 44. Tovar AR, Murguia F, Cruz C, Hernández Pando R, Aguilar Salinas CA, Pedraza Chavarri J, Correa Rotter R, Torres N. A soy protein diet alters hepatic lipid metabolism gene expresión and reduces serum lipids and renal fibrogenic cytokines in rats with chronic nephrotic síndrome. J Nutr 2002;132:2562-2569 45. Aguilar-Salinas CA, Rojas R, Francisco J. Gómez-Pérez, Eduardo García, Victoria Valles, Juan Manuel Ríos-Torres, Aurora Franco, Gustavo Olaiz, Jaime Sepúlveda, Juan A. Rull. Early onset type 2 diabetes in a Mexican, population-based, nation-wide survey: Am J Medicine 2002;113:569-574. 46. Gómez Pérez FJ, Hernandez Jimenez S, Aguilar Salinas CA, Rull JA. Insulin analogues: a critical review. Revista de Investigación Clínica 2002:54:527-541. 47. Robles-Osorio L, Ordoñez ML, Aguilar-Salinas CA, Aurón-Gómez M, Tusié-Luna MT, Gómez-Pérez FJ, Rull-Rodrigo JA. Familial hypercholesterolemia due to a ligand-defective apolipoprotein B-100. First case-report in a Mexican family. Archives of Medical Research 2003;34: 70-5 48. Canizales S, Aguilar Salinas CA, Auron Gomez M, Riba L, Tusie MT. Locus on chromosome 6p linked to elevated HDL-C serum levels, and to protection against premature atherosclerosis in a kindred with familial hypercholesterolemia. Circulation Research 2003:92:569-76 49. Aguilar Salinas CA. La regulación hormonal del catabolismo de las proteinas; El papel del glucagons y la proteina de soya. Revista de Investigación Clinica 2003:55:83-86 50. Boule NG, Tremblay A, Gonzalez Barranco J, Aguilar Salinas CA, Lopez JC, Despres JP, Bouchard C, Gomez Perez FJ, Castillo L, Rios JM. Insulin resístanse and abdominal adiposity in young men with documented malnutrition during the first year of life. Int J Obesity 2003;57:598-604. 51. Aguilar Salinas CA et al. Analysis of the agreement between the World Health Organization criteria and the National Cholesterol Education Program-III definition of the metabolic syndrome: Results from a population-based survey. Diabetes Care 2003;26: 1635. 52. Aguilar-Salinas CA, Velazquez Monroy O , Gómez-Pérez FJ, Gonzalez Chávez A, Lara Esqueda A, Molina Cuevas V, Rull-Rodrigo J, Tapia Conyer R for the ENSA 2000 Group. Characteristics of the patients with type 2 diabetes in México: results from a large population-based, nation-wide survey. Diabetes Care 2003:26:2021-2026 53. González-Barranco, J, Ríos-Torres JM, Castillo-Martínez L, López-Alvarenga JC, Aguilar-Salinas CA, Bouchard C, Deprès JP, Tremblay A. Effect of malnutrition during the first year of life on adulthood plasma insulin and glucose tolerance. Metabolism 2003;52: 1005-1011. 54. Armando Barriguete, Carlos A. Aguilar, Marie Rose Moro, Enrique Ríos, Sergio Lerin. Élever un enfant ce n’est pas seulement le nourrir. Approche ethnopsychanalytique de la crianza chez les Purépechas du Mexique. L ' a u t r e, Cliniques, cultures et sociétés , 2003, 4 : 347-35 55. Gulias A., Aguilar Salinas CA, Gomez Perez FJ, Rull JA.”The combination metformin/glyburide exerts its hypoglycemic effects by enhancing insulin secretion. Diabetes Nutrition & Metabolism 2003:16:268-276 56. del Bosque-Plata L, Aguilar-Salinas CA, Tusié-Luna MT, Ramírez-Jiménez S, Rodríguez-Torres M, Aurón-Gómez M, Ramírez E, Velasco-Pérez ML, Ramírez-Silva A, Gómez-Pérez FJ, Hanis C, Tsuchiya T, Yoshiuchi I, Cox N, Bell G. Association of the Calpain-10 Gene with Type 2 Diabetes Mellitus in a Mexican Population. Molecular Genetics and Metabolism 2004; 81:122-126. 57. Aguilar-Salinas CA, Rojas R , Gómez-Pérez FJ, Valles V, Ríos-Torres JM, Franco A, Olaiz G, Rull JA , Sepulveda J. High prevalence of the metabolic syndrome in México. Arch Med Res 2004; 35:76-81 58. Aguilar Salinas CA. Los fibratos y el síndrome metabólico. Journal of Cardiovascular Risk 2004; Suppl 1: 22-25 59. Rodríguez Carranza S, Aguilar Salinas CA Anormalidades metabólicas en pacientes con infección por VIH. Revista de Investigación Clinica 2004: 56: 193-208 60. Rhoopa Mehta, Beatriz Loredo, Ma Elena Sañudo, Sergio Hernandez Jiménez, Sandra I. Rodríguez Carranza, Francisco J. Gómez-Pérez, Juan A. Rull y Carlos A. Aguilar Salinas Epidemiología de las anormalidades metabólicas en pacientes con infección por VIH. Revista de Investigación Clinica 2004: 56: 209-221. 61. Carlos A. Aguilar Salinas, Margarita Zamora, Rita A. Gómez- Díaz, Rhoopa Mehta, Francisco J. Gómez Pérez and Juan A. Rull Familial combined hyperlipidemia: controversial aspects of its diagnosis and pathogenesis. Seminars of Vascular Medicine 2004: 4: 203-209 62. Aguilar Salinas CA, Rojas R, Gómez Pérez FJ, Franco A, Olaiz G, Rull JA, Sepulveda J. El síndrome metabólico: un concepto en evolución. Gac Med Mex 2004; 140; Supl2: S43-S50 63. Carlos A. Aguilar-Salinasa, Andréia Assis-Luores-Valeb, Benjamín Stockinsc, Hector Mario Rengifod, José Dondici Filhob, Abrahão Afiune Netob, Lísia Marcílio Rabelob, Kerginaldo Paulo Torresb, José Egídio Paulo de Oliveirab, Carlos Alberto Machado b, Eliana Reyes c, Victor Saavedra c, Fernando Florenzano c, Ma Victoria Hernández c, Sergio Hernandez Jiménez a, Erika Ramírez a, Cuauhtémoc Vazquez e, Saul Salinase, Ismael Hernández c, Octavio Medel c, Ricardo Moreno c, Paula Lugo c, Ricardo Alvaradof, Roopa Mehta a and Francisco J. Gómez Pérez aCiprofibrate therapy in patients with hypertriglyceridemia and low high density lipoprotein (HDL)-cholesterol: greater reduction of non- HDL cholesterol in subjects with excess body weight (The CIPROAMLAT study). Cardiovascular Diabetology 2004; 3(1):8-15 64. A Enrique Caballero, Adriano Delgado, Carlos A Aguilar-Salinas, Alberto Naranjo Herrera, Jose Luis Castillo, Tatiana Cabrera, Francisco J Gomez-Perez, Juan A. Rull. The differential effects of metformin on markers of endothelial activation and inflammation in subjects with Impaired Glucose Tolerance: A placebo-controlled, randomized, clinical trial. Journal of Clinical Endocrinology and Metabolism 2004; 89:3943-48 65. A. Huertas-Vázquez, J.P. del Rincón-Jarero, S. Canizales-Quinteros, Gerardo Vega-Hernández, L. Riba, S. Ramírez-Jiménez, C.A. Aguilar-Salinas, F.J. Gómez Pérez, M.T. Tusié-Luna. Replication of Linkage of Familial Combined Hyperlipidemia to Chromosome 1q21-q23 in Mexican Families. Annals of Human Genetics 2004;68(pte5):419-427. 66. Gómez-Díaz R, Aguilar-Salinas CA, Morán-Villota S, Barradas-González R, Herrera-Márquez R, Cruz López M, Kumate J, Wacher N. Lack of agreement between the revised criteria of impaired fasting glucose and impaired glucose tolerance in children with excess body weight. Diabetes Care 2004;27:2229-2233. 67. Lara Esqueda A, Aguilar Salinas CA, Velazquez O, Gómez Pérez FJ, Rosas M, Mehta R, Tapia R. The body mass index is a less sensitive tool for detecting cases with obesity related co-morbidities in short stature subjects. International Journal of Obesity 2004;28:1443-1450 68. Rodriguez Carranza S, Caceres M, Aguilar Salinas CA, Gomez Perez FJ, Herrera M, Pantoja JP, Rull JA Upper neck parathyroid adenomas are more frequently missed by Tc99-sestamibi scanning tha lower neck lesions. Endocrine practice 2004:10:472-477 69. Lara A, Rosas M, Pastelin G, Aguilar Salinas CA, Attie F, Velazquez Monroy O. Hipercolesterolemia e hipertension arterial en Mexico. Consolidacion urbana actual con obesidad, diabetes y tabaquismo. Archivos de Cardiologia de Mexico 2004; 74:231-245. 70. Lerman I, Lozano L, Villa AR, Hernandez Jimenez S, Weinger K, Caballero AE, Aguilar Salinas CA, Velasco ML, Gomez perez FJ, Rull JA. Psycosocial factors associated with poor diabetes self care management in a specialized center in Mexcio City. Biomedicine & Phamacotherapy. 2004;58:566- 570. 71. Canizales-Quinteros Samuel, Aguilar-Salinas Carlos A, Huertas Adriana, Ordóñez Ma. Luisa, Rodríguez Maribel, Venturas José Luis, Riba Laura, Ramírez Salvador, Salas-Montiel Rocío, Medina- Palacios Giovani, Miliar-García Angel, Rosales-León Luis, Ruiz-Ordaz Blanca, Zentella-Dehesa Alejandro, Ferré-D’Amare Adrian, Gómez-Pérez Francisco J, Tusié-Luna Ma Teresa. A novel ARH splice site mutation in a Mexican kindred with autosomal recessive hypercholesterolemia and evidence of possible interaction between the 1p35 and 15q25-26 loci in the expression of the disease. Human Genetics 2005;116 (1-2):114-120 E pub 2004 Nov 17. 72. Rosalba Rojas, Carlos A. Aguilar-Salinas, Francisco J. Gómez-Pérez, Victoria Valles, Aurora Franco, Gustavo Olaiz, Jaime Sepulveda, Juan A. Rull. Applicability of the National Cholesterol Education Program III (NCEP-III) Guidelines for treatment of dyslipidemia in a non-Caucasian population: A Mexican Nation-Wide Survey. Revista de Investigacion Clinica 2005;57:28-37. 73. Aguilar Salinas CA. Diabetes y tuberculosis: en el laberinto del subdesarrollo. Revista de Investigacion Clinica 2005;57:82-84. 74. Dominguez-Lopez A, Miliar-Garcia A, Segura-Kato YX, Riba L, Esparza-Lopez R, Ramirez-Jimenez S, Rodriguez-Torres M, Canizales-Quinteros S, Cabrera-Vasquez S, Fragoso-Ontiveros V, Aguilar-Salinas CA, Altamirano-Bustamante N, Calzada-Leon R, Robles-Valdes C, Bravo-Rios LE, Tusie-Luna MT. Mutations in MODY genes are not common cause of early-onset type 2 diabetes in Mexican families JOP. 2005;10;6(3):238-45. 75. Canizales-Quinteros S, Huertas-Vazquez A, Riba-Ramirez L, Monroy-Guzman A, Dominguez-Lopez A, Romero-Hidalgo S, Aguilar-Salinas C, Rodriguez-Torres M, Ramirez-Jimenez S, Tusie-Luna MT. Identifying different susceptibility loci associated with early onset diabetes and cardiovascular disease in Mexican families.Gac Med Mex. 2005;141(2):115-22 76. Rull JA, Aguilar-Salinas CA, Rojas R, Rios-Torres JM, Gómez-Pérez FJ, Olaiz G..Epidemiology of type 2 diabetes in Mexico. Archives of Medical Research 2005; 36: 188-96. 77. Aguilar-Salinas CA, Rojas R, Rios-Torres JM, Gómez-Pérez FJ, Olaiz G, Rull JA.The metabolic syndrome: a concept in evolution. Archives of Medical Research 2005: 36:223-31. 78. Aguilar-Salinas CA, Mehta R, Rojas R, Gómez-Pérez FJ, Olaiz G, Rull JA. Management of the metabolic syndrome as a strategy for preventing the macrovascular complications of type 2 diabetes: controversial issues. Current Diabetes Reviews 2005:1: 145-158. 79. Huertas-Vazquez A, Aguilar Salinas C, Lusis A, Cantor R, Canizales A, Lee J, Nuñez L, Metha R, Riba L, Jokiaho A, Tusie MT, Pajukanta P. Familial Combined Hyperlipidemia in Mexicans. Association with Upstream Transcription Factor 1 and linkage on chromosome 16q24.1. Arteriosclerosis Thrombosis and Vascular Biology 2005;25:1985-1991. 80. Tovar AR, Torre-Villalvazo I, Ochoa M, Elias AL, Ortiz V, Aguilar-Salinas CA, Torres N. Soy protein reduces hepatic lipotoxicity in hyperinsulinemic obese Zucker fa/fa rats. J Lipid Res. 2005: 46;1823-1832 81. Aguilar Salinas CA, Ramirez E, Gallegos J, Leyva O, Oseguera J, Lozano H, Gomez Perez FJ La hipertrigliceridemia y diabetes tipo 2. Gaceta Medica de México 2005; 141: (3): 201-205 82. Gómez-Díaz R, Martínez-Hernández A, Aguilar-Salinas CA, Violante R, López Alarcón M, Jiménez Villarruel M, Wacher Rodarte N, Solórzano-Santos F. Percentile Distribution of the Waist Circumference among Mexican Preadolescents of a primary school in Mexico City. Diabetes, Obesity and Metabolism 2005;7:716-21. 83. Robles L, Huerta A, Ordoñez ML, Canizales S, Diaz A, Gutierrez R, Riba L, Huertas A, Rodriguez M, Gomez Diaz R, Salinas S, Ongay L, Codiz G, Mora M, Mehta R, Gomez Perez FJ, Rull J, Rabes J, Tusie MT, Duran S, Aguilar Salinas CA. Mutational and genetic linkage analyses of autosomal dominant hypercholesterolemia in Mexico: Evidence for further genetic heterogeneity. Arch Med Res 2006;37:102-108 84. Aguilar Salinas CA. Gomez Pérez FJ. La declaración de Acapulco. Rev Investigacion Clinica 2006;58:71- 77 85. Weissglas D, Huertas Vazquez A, Canizalez S, Suviolahti E, Lee J, Aguilar Salinas CA, Tusie Luna MT, Taskinen MR, Pajukanta P. Common hepatic nuclear factor 4 alpha variants are associated with high serum lipid levels and the metabolic syndrome. Diabetes 2006; 55:1970-1977. 86. Aguilar-Salinas CA, Rojas R, Gonzalez-Villalpando C, Gomez-Perez FJ, Mehta R, Olaiz G, Rull JA, Cox DR.. Design and validation of a population-based definition of the metabolic syndrome. Diabetes Care. 2006 Nov;29:2420-6. 87. Navalon-Garcia K, Mendoza-Alcantar L, Diaz-Vargas ME, Martinez-Godinez MA, Reyna-Garfias H, Aguilar-Salinas CA, Riba L, Canizales-Quinteros S, Villarreal-Molina T, Gonzalez-Chavez A, Argueta- Villamar V, Tusie-Luna MT, Miliar-Garcia A. HNF-1alpha G574S is a functional variant with decreased transactivation activity. Diabet Med. 2006 Dec;23(12):1295-300. 88. Hernandez-Jimenez S, Pachón A, Aguilar Salinas CA, Andrade V, Reynoso R, Rios A, Reza A, Mehta R, Gonzalez O, Gomez Perez FJ, Perez B, Rull J. Radioiodine treatment in autoimmune hyperthyroidism: analysis of outcomes in relation to dosage. Arch Med Res 2007;38:185-189. 89. Catzin A, Orea A, Castillo L, Colin E, Asz D, Aguirre V, Herrera L, Valles V, Aguilar Salinas CA, Sierra J, Calva JJ. Human immunodeficiency virus-infected subjects have no altered myocardial perfusion. International Journal of Cardiology 2007; 122:90-2 90. Villarreal-Molina MT, Aguilar-Salinas CA, Rodríguez-Cruz M, Riaño D, Villalobos-Comparan M, Flores-Dorantes MT, Guerra-Garcia MT, Coral-Vazquez R, Huertas-Vazquez A, Brito-Zurita O, Canto-de Cetina T, Ortiz-Lopez G, Rosales-Escamilla A, Cruz-Bautista I, Menjivar M, Yescas-Gomez P, Gomez- Perez FJ, Könisberg-Feinstein M, Romero-Hidalgo S, Tusie-Luna MT, Canizales-Quinteros S. The ABCA1 R230C variant affects HDL cholesterol levels and body mass index in the Mexican Population: Association with obesity and obesity-related comorbidities. Diabetes 2007: 56: 1881-1887 91. Canizales-Quinteros S, Aguilar-Salinas CA, Ortiz-López MG, Rodríguez-Cruz M, Villarreal-Molina MT, Coral-Vázquez R, Huertas-Vázquez A, Hernández-Caballero A, López-Alarcón M, Brito-Zurita OR, Domínguez-Banda A, Martinez-Sánchez LR, Canto-de Cetina T, Vilchis-Dorantes G, Rosas-Vargas H, Granados-Silvestre MA, Medeiros-Domingo A, Menjivar M, Tusié-Luna MT.. Association of PPARG2 Pro12Ala variant with larger body mass index in Mestizo and Amerindian populations of Mexico. Hum Biol. 2007 Feb;79(1):111-9 92. Aguilar Salinas CA. Adiposidad abdominal como factor de riesgo para enfermedades crónicas. Salud Publica de mexico 2007;49:E311-E316. 93. Alkes L. Price, Nick Patterson, Fuli Yu, David Cox, Alicja Waliszewska, Gavin McDonald, Arti Tandon, Christine Schirmer, Julie Neubauer, Gabriel Bedoya, Marcela Tello-Ruiz, Laura Riba, Carlos Aguilar- Salinas, Samuel Canizales, Brian Henderson, Christopher Haiman, Cheryl Winkler, Teresa Tusie, Andres Ruiz-Linares & David Reich, A genomewide admixture map for Latino populations. American Journal of Human Genetics 2007; 80:1024-1036 94. Aguilar Salinas CA. Descripcion de la deficiencia de la proteina relacionada al receptor LDL tipo 6 (LRP6): implicaciones en la fisiopatologia de la diabetes tipo 2, la hipertension arterial y la ateroesclerosis. Rev Invest Clin 2007;59:4-7 95. Rabago-Rodriguez, Rocio; Gomez-Diaz, Rita; Tanus-Hajj, Janet; Avelar-Garnica, Francisco Jose; Ramirez-Soriano, Eleazar; Nishimura-Meguro, Elisa; Aguilar-Salinas, Carlos; Wacher, Niels. Carotid intima-media thickness in pediatric type 1 diabetes patients. Diabetes Care 2007;30:2599-2602 96. Olaiz G, Rojas R, Aguilar Salinas CA Rauda J, Villalpando J. Diabetes mellitus en adultos mexicanos. Resultados de la ENSA 2000. Salud Publica de Mexico 2007; 49 supl 3: S331-S337 97. Robles-Osorio L, Aguilar-Salinas CA, Mehta R, Gómez-Pérez FJ, Rull JA. The fasting plasma glucose value with the best performance for detecting an abnormal response in the oral glucose tolerance test is below the “impaired fasting glucose“ range in at-risk individuals. Endocrine Practice 2007;13:583-589 98. Carlos A.Aguilar Salinas, Ivette Cruz-Bautista, Roopa Mehta, Ma Teresa Villarreal-Molina, Francisco J. Gómez Pérez, Ma Teresa Tusié-Luna, Samuel Canizales-Quinteros. The ATP-Binding Cassette Transporter Subfamily A Member 1 (ABC-A1) and Type 2 Diabetes: An Association Beyond HDL Cholesterol. Current Diabetes Reviews 2007:3:264-267 99. Aguilar Salinas CA., Gomez Diaz RA, Gomez Perez FJ Inactivation of adipocyte LRP1 and increased insulin sensitivity: effect mediated by adiponectin? http://www.jci.org/cgi/eletters/JCI31929v1 100. Catzin-Kuhlmann A, Castillo-Martínez L, Colín-Ramírez E, Valles V, Aguilar-Salinas CA, Sierra J, Calva JJ.. Highly atherogenic lipid phenotypes and antiretroviral therapy duration in human immunodeficiency virus patients. Arch Med Res. 2008;39:84-91 101. Aguilar Salinas CA, Canizales Quinteros S, Rojas Martinez R, Garcia Garcia E, Olaiz G, Gomez Perez FJ, Tusie Luna MT. Colaboraciones exitosas entre tres instituciones mexicanas en el estudio de las dislipidemias, la obesidad y la diabetes. Gaceta Médica de Mexico 2007;143:355-364. 102. J Jaspal S Kooner, John C Chambers, Carlos A Aguilar-Salinas, David A Hinds, Craig L Hyde, Gregory R Warnes, Francisco J Gómez Pérez, Kelly A Frazer, Paul Elliott, James Scott, Patrice M Milos, David R Cox, John F Thompson.Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides Nature Genetics 2008;40:149-151 103. Menjívar M, Granados-Silvestre MA, Montúfar-Robles I, Herrera M, Tusié-Luna MT, Canizales- Quinteros S, Aguilar-Salinas CA, Ortiz-López MG. High frequency of T130I mutation of HNF4A gene in Mexican patients with early onset type 2 diabetes”. Clinical Genetics 2008;73:185-7 104. M. Teresa Villarreal-Molina1*, M. Teresa Flores-Dorantes1*, Olimpia Arellano-Campos2, Marisela Villalobos-Comparan1, Maricela Rodríguez-Cruz3, Ruben Ramirez-Campuzano4, Adriana Huertas- Vazquez, Niels H. Wacher, Marta Menjivar M. Teresa Tusie-Luna, Miguel Cruz-Lopez, Carlos A. Aguilar-Salinas, Samuel Canizales-Quinteros1 and The Metabolic Study Group#Association of the ABCA1 R230C Variant with Early-Onset Type 2 Diabetes in the Mexican Population. Diabetes 2008;57:509-13. 105. A. Huertas-Vazquez, C. Plaisier, D. Weissglas-Volkov, S. Canizales-Quinteros, I. Cruz-Bautista, E. Nikkola, M. Herrera-Hernandez, A. Davila-Cervantes, T. Tusie-Luna, M.R. Taskinen, C. Aguilar-Salinas, P Pajukanta. TCF7L2 is associated with high serum triglycerides and differentially expressed in adipose tissue in families with familial combined hyperlipidemia. Diabetologia 2008;51;62-9 106. Janet S. Sinsheimer, Chris Plaisier, Adriana Huertas-Vazquez,Carlos Aguilar-Salinas, Teresa Tusie- Luna, Paivi Pajukanta, Kenneth Lange. Estimating Ethnic Admixture from Pedigree Data. Am J Human Genetics 2008 Mar;82(3):748-55. 107. Juan A Rivera, Onofre Muñoz-Hernández, Martín Rosas-Peralta, Carlos A Aguilar-Salinas, Barry M Popkin, Walter C Willett. Consumo de bebidas para una vida saludable: recomendaciones para la población mexicana. Salud Publica de México 2008; 50:173-195. 108. Villalpando-Berumen JM, Mejia-Arango S, Aguilar-Salinas CA, Ordonez-Sanchez ML, Gutierrez- Robledo LM.. APOE4, Alzheimer’s Disease and Cognitive Performance in the Mexican Mestizo Elderly. J Am Geriatr Soc. 2008 Apr;56(4):677-82. 109. José Pérez-Jáuregui, Ana María González- Cardel, Gabriela Olay- Fuentes, Alfredo Reza-Albarrán, Roopa Mehta, Carlos A. Aguilar-Salinas.The inclusion of educational messages in laboratory reports aids to complete the diagnostic workup of hyperglycemia. Diabetes Care 2008, 31:882-883 110. Rivera JA, Muñoz-Hernández O, Rosas-Peralta M, Aguilar-Salinas CA, Popkin BM, Willett WC. Beverage consumption for a healthy life: recommendations for the Mexican population. Rev Invest Clin. 2008;60:157-80. 111. Lee JC, Weissglas-Volkov D, Kyttälä M, Dastani Z, Cantor RM, Sobel EM, Plaisier CL, Engert JC, van Greevenbroek MM, Kane JP, Malloy MJ, Pullinger CR, Huertas-Vazquez A, Aguilar-Salinas CA, Tusie- Luna T, de Bruin TW, Aouizerat BE, van der Kallen CC, Croce CM, Aqeilan RI, Marcil M, Viikari JS, Lehtimäki T, Raitakari OT, Kuusisto J, Laakso M, Taskinen MR, Genest J, Pajukanta P.WW-Domain- Containing Oxidoreductase Is Associated with Low Plasma HDL-C Levels.Am J Hum Genet. 2008 Aug;83(2):180-92. 112. Villalobos-Comparán M, Teresa Flores-Dorantes M, Teresa Villarreal-Molina M, Rodríguez-Cruz M, García-Ulloa AC, Robles L, Huertas-Vázquez A, Saucedo-Villarreal N, López-Alarcón M, Sánchez- Muñoz F, Domínguez-López A, Gutiérrez-Aguilar R, Menjivar M, Coral-Vázquez R, Hernández- Stengele G, Vital-Reyes VS, Acuña-Alonzo V, Romero-Hidalgo S, Ruiz-Gómez DG, Riaño-Barros D, Herrera MF, Gómez-Pérez FJ, Froguel P, García-García E, Teresa Tusié-Luna M, Aguilar-Salinas CA, Canizales-Quinteros S.The FTO Gene Is Associated With Adulthood Obesity in the Mexican Population. Obesity (Silver Spring). 2008 Oct;16(10):2296-301. Epub 2008 Jul 31. 113. S Erdine, YM Ro, H-F Tse, LG Howes, CA Aguilar-Salinas, H Chaves, R Guindy, P Chopra, RA Moller, IM Schou, on behalf of the Gemini-AALA Investigators. Single-pill amlodipine/atorvastatin helps patients of diverse ethnicity attain recommended goals for blood pressure and lipids (The Gemini-AALA study). J Hum Hypertens. 2009 Mar;23(3):196-210. Epub 2008 Sep 18. 114. Carlos A. Aguilar-Salinas, Eduardo García García, Lorena Robles, Daniela Riaño, Doris Georgina Ruiz- Gomez, Ana Cristina García-Ulloa, Marco A Melgarejo, Margarita Zamora, Luz E Guillen-Pineda, Roopa Mehta, Samuel Canizales-Quinteros, Ma Teresa Tusie Luna, Francisco J. Gómez-Pérez. High adiponectin concentrations are associated with the metabolically healthy obese phenotype. J Clin Endoc Metab 2008; 93(10):4075-9 115. Córdova-Villalobos JA, Barriguete-Meléndez JA, Lara-Esqueda A, Barquera S, Rosas-Peralta M, Hernández-Avila M, León-May ME, Admon L, Aguilar-Salinas CA.Chronic non-communicable diseases in Mexico: epidemiologic synopsis and integral prevention. Salud Publica Mex. 2008 Sep- Oct;50(5):419-27. Review. Spanish 116. González-Ortiz M, Guerrero-Romero JF, Violante-Ortiz R, Wacher-Rodarte N, Martínez-Abundis E, Aguilar-Salinas C, Islas-Andrade S, Arechavaleta-Granell R, González-Canudas J, Rodríguez-Morán M, Zavala-Suárez E, Ramos-Zavala MG, Metha R, Revilla-Monsalve C, Beltrán-Jaramillo TJ. Efficacy of glimepiride/metformin combination versus glibenclamide/metformin in patients with uncontrolled type 2 diabetes mellitus.J Diabetes Complications. 2009 Nov-Dec;23(6):376-9. Epub 2008 Oct 11 117. Arjona R, Gomez Diaz R, Aguilar Salinas CA. El sindrome metabólico en niños y adolescentes. Boletin Medico del Hospital Infantil de Mexico 2008;65:488-502. 118. Plaisier CL, Kyttälä M, Weissglas-Volkov D, Sinsheimer JS, Huertas-Vazquez A, Riba L, Ramírez- Jiménez S, de Bruin TW, Tusié-Luna T, Aouizerat BE, Pullinger CR, Malloy MJ, Kane JP, Cruz-Bautista I, Herrera MF, Aguilar-Salinas C, Kuusisto J, Laakso M, Taskinen MR, van der Kallen CJ, Pajukanta P. Galanin preproprotein is associated with elevated plasma triglycerides Arterioscler Thromb Vasc Biol. 2009 Jan;29(1):147-52. Epub 2008 Nov 6. 119. Aguilar-Salinas CA, Canizales-Quinteros S, Rojas-Martínez R, Mehta R, Villarreal-Molina MT, Arellano-Campos O, Riba L, Gómez-Pérez FJ, Tusié-Luna MT. Hypoalphalipoproteinemia in populations of Native American ancestry: an opportunity to assess the interaction of genes and the environment. Current Opinion in Lipidology 2009 Apr;20(2):92-7. 120. Almeda P, Cuevas D, Aguilar Salinas CA. Metabolic syndrome and non-alcoholic fatty liver disease. Annals of Hepatology 2009;8 (Supl1) S18-S24. 121. Aude-Rueda O, Aguilar-Nungaray G, Villa-Romero A, Cruz-Bautista I, Aguilar-Salinas CA. The hyperlipidemia diagnosis based in phenotype. Rev Med Inst Mex Seguro Soc. 2009 Mar- Apr;47(2):121-8. 122. Cuevas-Ramos D, Almeda-Valdes P, Aguilar-Salinas CA, Cuevas-Ramos G, Cuevas-Sosa AA, Gomez- Perez FJ. The Role of Fibroblast Growth Factor 21 (FGF21) on Energy Balance, Glucose and Lipid Metabolism..Curr Diabetes Rev. 2009; 5(4):216-20 123. Florez JC, Price AL, Campbell D, Riba L, Parra MV, Yu F, Duque C, Saxena R, Gallego N, Tello-Ruiz M, Franco L, Rodríguez-Torres M, Villegas A, Bedoya G, Aguilar-Salinas CA, Tusié-Luna MT, Ruiz-Linares A, Reich D. Strong association of socioeconomic status with genetic ancestry in Latinos: implications for admixture studies of type 2 diabetes. Diabetologia. 2009 Aug;52(8):1528-36. Epub 2009 Jun 13. 124. Rosenstock J, Aguilar-Salinas C, Klein E, Nepal S, List J, Chen R; for the CV181-011 Study Investigators. Effect of saxagliptin monotherapy in treatment-naïve patients with type 2 diabetes. Curr Med Res Opin. 2009; 25: 2401-2411 125. Plaisier CL, Horvath S, Huertas-Vazquez A, Cruz-Bautista I, Herrera MF, Tusie-Luna T, Aguilar-Salinas C, Pajukanta P. A systems genetics approach implicates USF1, FADS3, and other causal candidate genes for familial combined hyperlipidemia. PLoS Genet. 2009 Sep;5(9):e1000642. Epub 2009 Sep 11. 126. Torre-Villalvazo I, Gonzalez F, Aguilar-Salinas CA, Tovar AR, Torres N. Dietary soy protein reduces cardiac lipid accumulation and the ceramide concentration in high-fat diet-fed rats and ob/ob mice. Journal of Nutrition 2009, 139(12):2237-43 Publicado en linea Oct 14,2009 127. Daphna Weissglas-Volkov, Christopher L. Plaisier, Adriana Huertas-Vazquez, Ivette Cruz-Bautista, Daniela Riaño-Barros, Miguel Herrera-Hernandez, Laura Riba, Rita M. Cantor, Janet S. Sinsheimer, Carlos A. Aguilar-Salinas, Teresa Tusie-Luna, Päivi Pajukanta. Identification of two common variants contributing to serum apolipoprotein B levels in Mexicans. Arteriosclerosis Thrombosis and Vascular Biology 2010 Feb;30(2):353-9. Publicado en linea Dic 8,2009 128. Almeda-Valdes P, Cuevas-Ramos D, Mehta R, Gomez-Perez FJ, Aguilar-Salinas CA. UKPDS Risk Engine, Decode and Diabetes PHD Models for the Estimation of Cardiovascular Risk in Patients with Diabetes.Curr Diabetes Rev. 2010;6:1-8 129. Barriguete-Meléndez JA, Unikel-Santoncini C, Aguilar-Salinas C, Córdoba-Villalobos JA, Barquera S, Shamah T, Rivera-Dommarco J, Hernández-Avila M. Prevalence of abnormal eating behaviors in adolescents: results of a population-based nationwide survey (Mexican Health and Nutrition Survey 2006). Salud Pública Méx 2009:51:Supl4:S638-S644 130. Daphna Weissglas-Volkov, Carlos A. Aguilar-Salinas, Janet S. Sinsheimer, Laura Riba, Adriana Huertas-Vazquez, Maria L. Ordoñez-Sánchez , Rosario Rodriguez-Guillen, Rita M. Cantor, Teresa Tusie-Luna, Päivi Pajukanta. Investigation of variants identified in Caucasian genome-wide association studies for plasma HDL cholesterol and triglycerides levels in Mexican dyslipidemic study samples. Circulation Cardiovascular genetics 2010;3:31-38 131. Hector García Alcala, Daniel Cuevas-Ramos, Paloma Almeda-Valdés, Carlos A Aguilar-Salinas. The prevalence of overweight and obesity had a two-fold increment between 1994 and 2008 in Mexican college students "Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy"2010:3 79–85 132. Gomez-Perez FJ, Cuevas-Ramos D, Valdes PA, Aguilar-Salinas CA, Mehta R, Rull JA, Gómez-Pérez FJ.Beta-cell adenomas without hyperinsulinemia using highly specific insulin radioimmunoassays. A case report and review of the literature.Endocr Pract. 2010 Jul-Aug;16(4):660-3 133. Flores-Dorantes T, Arellano-Campos O, Posadas-Sánchez R, Villarreal-Molina T, Medina-Urrutia A, Romero-Hidalgo S, Yescas-Gómez P, Pérez-Méndez O, Jorge-Galarza E, Tusié-Luna T, Villalobos- Comparán M, Jacobo-Albavera L, Villamil-Ramírez H, López-Contreras BE, Aguilar-Salinas CA, Posadas-Romero C, Canizales-Quinteros S. Association of R230C ABCA1 gene variant with low HDL-C levels and abnormal HDL subclass distribution in Mexican school-aged children. Clin Chim Acta. 2010;411(17-18):1214-7 134. Acuña-Alonzo V, Flores-Dorantes T, Kruit JK, Villarreal-Molina T, Arellano-Campos O, Hünemeier T, Moreno-Estrada A, Ortiz-López MG, Villamil-Ramírez H, León-Mimila P, Villalobos-Comparan M, Jacobo-Albavera L, Ramírez-Jimenez S, Sikora M, Zhang LH, Pape TD, Granados-Silvestre MD, Montufar-Robles I, Tito AM, Zurita C, Bustos-Arriaga J, Cedillo-Barrón L, Gómez-Trejo C, Barquera- Lozano R, Vieira-Filho JP, Granados J, Romero-Hidalgo S, Huertas-Vázquez A, González-Martín A, Gorostiza A, Bonatto SL, Rodríguez-Cruz M, Wang L, Tusié-Luna T, Aguilar-Salinas CA, Lisker R, Moisés RS, Menjivar M, Salzano FM, Knowler WC, Bortolini MC, Hayden MR, Baier LJ, Canizales-Quinteros S. A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans. Hum Mol Genet. 2010 Jul 15;19(14):2877-85. 135. Barquera S, Campos-Nonato I, Hernández-Barrera L, Villalpando S, Rodríguez-Gilabert C, Durazo- Arvizú R, Aguilar-Salinas CA. Hypertension in Mexican adults: results from the National Health and Nutrition Survey 2006. Salud Publica de Mexico 2010:52 Supl1:S63-S71 136. Rojas R, Aguilar-Salinas CA, Jimenez A, Shamah T, Rauda J, Avila-Burgos L, Villalpando S, Lazcano Ponce E. “Metabolic Syndrome in Mexican adults. Results from the National Health and Nutrition Survey 2006”. Salud Pública Méx. 2010:52 (supl1) S11-S18. 137. Aguilar-Salinas CA, Gómez Pérez FJ, Rull JA, Villalpando S, Barquera S, Rojas R. Prevalence of dyslipidemias in the 2006 Encuesta Nacional de Salud y Nutrición. 2009 Salud Pública Méx. 2010:52 (supl1) S44-S53 138. Gómez-Pérez FJ, Rojas R, Villalpando S, Barquera S, Rull JA, Aguilar-Salinas CA. Prevention of cardiovascular disease based on the modification of low density lipoprotein cholesterol (LDL-C) levels: A huge challenge for the Mexican health system. Salud Pública Méx. 2010:52 (supl1) S54-S63 139. Barquera S, Campos-Nonato I, Carrión-Rábago C, Villalpando S, López-Ridaura R, Rojas R, Aguilar- Salinas CA. “Methodology of the National Health and Nutrition Survey 2006”. Salud Pública Méx. 2010:52 (supl1) S4-S10 140. Jimenez Corona A, Rojas Martinez R, Gómez-Pérez FJ, Aguilar-Salinas CA. Early onset type 2 diabetes in a Mexican, population-based, nation-wide survey: Results of the Encuesta Nacional de Salud y Nutrición 2006. Salud Pública Méx 2010: 52 (supl1). S27-S35 141. Villalpando S, Shamah-Levy T, Rojas R, Aguilar-Salinas CA. Trends for type 2 diabetes and other cardiovascular risk factors in Mexico from 1993-2006. Salud Pública Méx 2010: 52 (supl1). S72-S79 142. Garduño-Garcia JJ, Alvirde-Garcia U, López-Carrasco G,Padilla Mendoza ME, Mehta R, Arellano- Campos O, Choza R, Sauque L, Garay-Sevilla ME, Malacara JM, Gomez-Perez FJ, Aguilar-Salinas CA. Thyrotropin and free thyroxine concentrations are associated with differing metabolic markers in euthyroid subjects. European Journal of Endocrinology 2010;163(2):273-8 143. Aguilar Salinas CA,Gómez Díaz R, Tusié Luna MT. Cincuenta años de estudio de las hiperlipidemias primarias: El caso de la Hiperlipidemia familiar combinada. Invest Clin 2010, 51(2): 145 – 158. 144. Almeda-Valdes P, Cuevas-Ramos D, Mehta R, Gomez-Perez FJ, Cruz-Bautista I, Arellano-Campos O, Navarrete-Lopez M, Aguilar-Salinas CA. Total and High Molecular Weight Adiponectin have Similar Utility for the Identification of Insulin Resistance. Cardiovascular Diabetology 2010, 9:26. 145. Herrera MF, Pantoja JP. Velazquez D, Cabiedes J, Aguilar Salinas CA, Garcia E, Rivas A, Villeda C Hernandez D, Davila A, Zarain A. Potential additional effect of omentectomy on metabolic syndrome, acute phase reactants and inflammatory mediators in grade II obese patients undergoing laparoscopic Roux en Y gastric bypass. Diabetes Care 2010:33:1413-1418 146. Cuevas-Ramos D, Almeda-Valdes P, Gómez-Pérez FJ, Meza-Arana CE, Cruz-Bautista I, Arellano- Campos O, Navarrete-López M, Aguilar-Salinas CA. Daily Physical Activity, Fasting Glucose, Uric Acid and Body Mass Index are Independent Factors Associated with Serum Fibroblast Growth Factor 21 Levels. European Journal of Endocrinology 2010;163(3):469-77 147. Gomez-Perez FJ, Aguilar-Salinas CA, Almeda-Valdes P, Cuevas-Ramos D, Lerman Garber I, Rull JA HbA1c for the diagnosis of diabetes mellitus in a developing country. A position article. Arch Med Res 2010;41:302-308 148. Mehta R, Del Moral ME, Aguilar Salinas CA. Epidemiologia de la diabetes en el anciano. Revista de Investigacion Clinica 2010;62:305-311. 149. Lerman-Garber I, Aguilar-Salinas C, Tusié-Luna T, Velásquez D, Lobato-Valverde M, Osornio-Flores M, Gómez-Pérez FJ, Granados J, Villa A, Velasco ML, Rull-Rodrigo JA. Diabetes tipo 2 de inicio temprano. Experiencia en una institución de tercer nivel de atención médica. Gac Méd Méx Vol. 146 No. 3, 2010 179-184. 150. Rosas Guzmán J, Lyra R, Aguilar-Salinas CA, Cavalcanti S, Escaño F, Tambasia M, Duarte E and the ALAD consensus group. Treatment of type 2 diabetes in Latin-America: Consensus statement organized by Medical Societies from 17 Latin-American countries. Pan-American Journal of Public Health 2010;28(6):463–71. 151. Daniel Cuevas Ramos, Roopa Mehta, Julieta De La Luz Castro, Rutila Castañeda Limones, Ernesto García Rubí, Carlos A Aguilar Salinas."Awareness Of Abdominal Adiposity As A Cardiometabolic Risk Factor (The 5a Study): the Mexican Case. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2011:4: 107-17 152. 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The SIGMA (Slim Initiative in Genomic Medicine for the Americas) Type 2 Diabetes Consortium* The SIGMA Type 2 Diabetes Consortium; Writing team, Williams AL, Jacobs SB, Moreno-Macías H, Huerta-Chagoya A, Churchhouse C, Márquez-Luna C, García-Ortíz H, José Gómez-Vázquez M, Burtt NP, Aguilar-Salinas CA, González-Villalpando C, Florez JC, Orozco L, Haiman CA, Tusié-Luna T, Altshuler et al. Sequence variants in SLC16A11 are common risk factor for type 2 diabetes in Mexico. Nature. 2014 Feb 6;506(7486):97-101. Publicado en línea Dec 25. doi: 10.1038/nature12828. ISSN: 1476-4687. doi: 10.1038/nature12828 214. Aschner P. Aguilar Salinas CA, Aguirre L, Franco L, Gagliardino JJ, Gorban A, Seclen S, Vinocour M. Diabetes in South and Central America: an update far 2013 for the IDF Diabetes Atlas. Diabetes Res Clin Pract. 2014 Feb;103(2):238-43. ISSN: 1872-8227. doi: 10.1016/j.diabres.2013.11.010 215. Gómez-Díaz RA, Garibay-Nieto N, Wacher-Rodarte N, Aguilar-Salinas CA. Epidemiology of type 1 diabetes in Latin America. Curr Diabetes Rev. 2014 Feb 23. 2014 Mar;10(2):75-85 [Epub ahead of print]-ISSN: 1875-6417. http://www.eurekaselect.com/120561/article 216. Larrieta-Carrasco E, Acuña-Alonzo V, Velázquez-Cruz R, Barquera-Lozano R, León-Mimila P, Villamil- Ramírez H, Menjivar M, Romero-Hidalgo S, Méndez-Sánchez N, Cárdenas V, Bañuelos-Moreno M, Flores YN, Quiterio M, Salmerón J, Sánchez-Muñoz F, Villarreal-Molina T, Aguilar-Salinas CA, Canizales-Quinteros S. PNPLA3 I148M polymorphism is associated with elevated alanine transaminase levels in Mexican Indigenous and Mestizo populations. Mol Biol Rep. 2014 Jul;41(7):4705-11 ISSN: 1573-4978. doi: 10.1007/s11033-014-3341-0. 217. Jabbour SA, Hardy E, Sugg J, Parikh S; Study 10 Group.Dapagliflozin is effective as add-on therapy to sitagliptin with or without metformin: a 24-week, multicenter, randomized, double-blind, placebo- controlled study. Diabetes Care. 2014 Mar;37(3):740-50. doi: 10.2337/dc13-0467. Epub 2013 Oct 21.ISSN: 1935-5548 218. Aguilar-Salinas CA, Tusie-Luna MT, Pajukanta P.Genetic and environmental determinants of the susceptibility of Amerindian derived populations for having hypertriglyceridemia. Metabolism 2014; Publicado en linea Marzo 30,2014. 2014 Jul;63(7):887-94 ISSN: 1532-8600. doi: 10.1016/j.metabol.2014.03.012. 219. The Global Burden of Metabolic Risk Factors for Chronic Diseases Collaboration (Aguilar Salinas CA entre otros). Cardiovascular disease, chronic kidney disease, and diabetes mortality burden of cardiometabolic risk factors from 1980 to 2010: a comparative risk assessment. The Lancet Diabetes & Endocrinology Early Online Publication, 2014;Aug;2(8):634-47 ISSN:2213-8595. doi: 10.1016/S2213-8587(14)70102-0 220. Arthur Ko, Rita M. Cantor, Daphna Weissglas-Volkov, Elina Nikkola, Prasad MV Linga Reddy, Janet S. Sinsheimer, Bogdan Pasaniuc, Robert Brown, Marcus Alvarez, Alejandra Rodriguez, Rosario Rodriguez-Guillen, Ivette C. Bautista, Olimpia Arellano-Campos, Linda L. Muñoz-Hernández, Veikko Salomaa, Jaakko Kaprio, Antti Jula, Matti Jauhiainen, Markku Heliövaara, Olli Raitakari, Terho Lehtimäki, Johan G. Eriksson, Markus Perola, Kirk E. Lohmueller, Niina Matikainen, Marja-Riitta Taskinen, Maribel Rodriguez-Torres, Laura Riba,Teresa Tusie-Luna, Carlos A. Aguilar-Salinas, Päivi Pajukanta. Amerindian-specific regions under positive selection harbor new lipid variants in Latinos. Nat Commun. 2014 Jun 2;5:3983.ISSN: 2041-1723. doi: 10.1038/ncomms4983 221. Karol Estrada, Ingvild Aukrust, Lise Bjørkhaug, Noël P. Burtt, Josep M. Mercader, Humberto García- Ortiz, Alicia Huerta-Chagoya, Hortensia Moreno-Macías, Geoffrey Walford, Clicerio González- Villalpando, Jason Flannick, Amy L. Williams, Michael Boehnke, Lorena Orozco, Christopher A. Haiman, Teresa Tusié-Luna, Carlos A. Aguilar-Salinas, David Altshuler, Pål R. Njølstad, Jose C. Florez, Daniel G. MacArthur, for the SIGMA Type 2 Diabetes Consortium Association of a low-frequency variant in HNF1Awith type 2 diabetes in a Latino population. JAMA. 2014;311(22):2305-2314 ISSN: 1538-3598. Doi: 10.1001/jama.2014.6511 222. Sánchez T, Contreras-Yáñez I, Elías-López D, Aguilar Salinas CA, Pascual-Ramos V. Prevalence of lipid phenotypes, serum lipid behaviour over follow-up and predictors of serum lipid levels in a cohort of Mexican Mestizo early rheumatoid arthritis patients treated with conventional disease-modifying anti-rheumatic drugs. Clin Exp Rheumatol. 2014; 32 (4): 509-515. ISSN: 0392-856X. http://www.clinexprheumatol.org/abstract.asp?a=7771 223. Ivette Cruz-Bautista, Roopa Mehta, Javier Cabiedes, Cristina Garcia-Ulloa, Luz Elizabeth Guillen- Pineda, Francisco J Gómez-Pérez and Carlos A Aguilar-Salinas. VLDL triglyceride content and particle number are determined by different factors in Familial Combined Hyperlipidemia. Clin Chim Acta. 2014 Aug 27;438C:160-165. ISSN: 1873-3492.ISSN: 1873-3492 doi: 10.1016/j.cca.2014.08.018 224. Ortiz-Bautista R, Aguilar-Salinas C, Monroy-Guzmán A. Caloric restriction: about its positive metabolic effects and cellular impact. Cir Cir. 2013 Sep-Oct;81(5):459-64. ISSN: 1873-3492. http://www.medigraphic.com/pdfs/circir/cc-2013/cc135p.pdf

225. Majithia AR1, Flannick J2, Shahinian P2, Guo M3, Bray MA2, Fontanillas P2, Gabriel SB2; GoT2D Consortium; NHGRI JHS/FHS Allelic Spectrum Project; SIGMA T2D Consortium; T2D-GENES Consortium, Rosen ED4, Altshuler D5 Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes. Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):13127-32. ISSN: 1091-6490. doi: 10.1073/pnas.1410428111 226. Rodríguez-Ventura AL1, Pelaez-Ballestas I2, Sámano-Sámano R3, Jimenez-Gutierrez C3, Aguilar- Salinas C4.Barriers to lose weight from the perspective of children with overweight/obesity and their parents: A sociocultural approach. J Obes. 2014;2014:575184. doi: 10.1155/2014/575184. Epub 2014 Oct 2.. ISSN: 2090-0716 227. Hernández-Jiménez S, García-Ulloa C, Mehta R, Aguilar-Salinas CA, Kershenobich-Stalnikowitz D. Innovative Models for the Empowerment of Patients with Type 2 Diabetes: The CAIPaDi Program. Recent Pat Endocr Metab Immune Drug Discov. 2014;8(3):202-9 ISSN: 1872-2148 http://www.eurekaselect.com/125991/article 228. Almeda-Valdes P, Cuevas-Ramos D, Mehta R, Muñoz-Hernandez L, Cruz-Bautista I, Perez-Mendez O, Tusie-Luna MT, Gomez-Perez FJ, Pajukanta P, Matikainen N, Taskinen MR, Aguilar-SalinasCA. Determinants of postprandial lipemia and postprandial apo A-V levels in individuals with familial combined hyperlipidemia. BMC Endocr Disord. 2014 Nov 25;14(1):90 PMID:2542521. ISSN: 1472- 6823. doi: 10.1186/1472-6823-14-90. 229. García-Villegas EA, Lerman-Garber I, Flores-Suárez LF, Aguilar-Salinas C, González HM, Villa-Romero AR. Estimation of the prognostic value of Metabolic Syndrome for the development of cardiovascular disease in a cohort of premenopausal women with Systemic Lupus Erythematosus. Med Clin (Barc). 2015 Apr 8;144(7):289-96pii: S0025-7753(14)00693-9. doi: 10.1016/j.medcli.2014.06.018. doi: 10.1016/j.medcli.2014.06.018 ISSN: 0025-7753 230. . Palmer ND, Goodarzi MO, Langefeld CD, Wang N, Guo X, Taylor KD, Fingerlin TE, Norris JM, Buchanan TA, Xiang AH, Haritunians T, Ziegler JT, Williams AH, Stefansovski D, Cui J, Mackay AW, Henkin LF, Bergman RN, Gao X, Gauderman J, Varma R, Hanis CL, Cox NJ, Highland HM, Below JE, Williams AL, Burtt NP, Aguilar-Salinas CA, Huerta-Chagoya A, Gonzalez-Villalpando C, Orozco L, Haiman CA, Tsai MY, Johnson WC, Yao J, Rasmussen-Torvik L, Pankow J, Snively B, Jackson RD, Liu S, Nadler JL, Kandeel F, Chen YI, Bowden DW, Rich SS, Raffel LJ, Rotter JI, Watanabe RM, Wagenknecht LE. Genetic Variants Associated with Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium. Diabetes. 2015 May;64(5):1853-66. pii: DB_140732. ISSN: 1939-327X doi: 10.2337/db14-0732 231. Scirica BM, Braunwald E, Raz I, et al; SAVOR–TIMI 53 Steering Committee and Investigators (Aguilar Salinas CA entre otros). Heart failure, saxagliptin, and diabetes mellitus: observations from the SAVOR-TIMI 53 randomized trial. Circulation. 2014;130:10: 1579-88. ISSN: 1524-4539. doi: 10.1161/CIR.0000000000000330 232. Pattzi HM, Pitale S, Alpizar M, Bennett C, O'Farrell AM, Li J, Cherrington JM, Guler HP; PHX1149- PROT202 Study Group (Aguilar Salinas CA entre otros 96). Dutogliptin, a selective DPP4 inhibitor, improves glycaemic control in patients with type 2 diabetes: a 12-week, double-blind, randomized, placebo-controlled, multicentre trial. Diabetes Obes Metab. 2010 Apr;12(4):348-55. ISSN: 1463-1326. PMID:20380656. 233. León-Mimila P, Vega-Badillo J, Gutiérrez-Vidal R, Villamil-Ramírez H, Villareal-Molina T, Larrieta- Carrasco E, López-Contreras BE, Kauffer LR, Maldonado-Pintado DG, Méndez-Sánchez N, Tovar AR, Hernández-Pando R, Velázquez-Cruz R, Campos-Pérez F, Aguilar-Salinas CA, Canizales-Quinteros S. A genetic risk score is associated with hepatic triglyceride content and non-alcoholic steatohepatitis in Mexicans with morbid obesity. Exp Mol Pathol. 2015 Apr;98(2):178-83. pii: S0014-4800(15)00014-3. doi: 10.1016/j.yexmp.2015.01.012. [Epub ahead of print. ISSN: 1096-0945. 234. Parra-Salcedo F, Contreras-Yáñez I, Elías-López D, Aguilar-Salinas CA, Pascual-Ramos V. Prevalence, incidence and characteristics of the metabolic syndrome (MetS) in a cohort of Mexican Mestizo early rheumatoid arthritis patients treated with conventional disease modifying anti-rheumatic drugs: the complex relationship between MetS and disease activity. Arthritis Res Ther. 2015 Feb 20;17(1):34 ISSN: 1478-6362. doi: 10.1186/s13075-015-0549-x. 235. Hajifathalian K, Ueda P, Lu Y, Woodward M, Ahmadvand A, Aguilar-Salinas CA, Azizi F, Cifkova R, Di Cesare M, Eriksen L, Farzadfar F, Ikeda N, Khalili D, Khang YH, Lanska V, León-Muñoz L, Magliano D, Msyamboza KP, Oh K, Rodríguez-Artalejo F, Rojas-Martinez R, Shaw JE, Stevens GA, Tolstrup J, Zhou B, Salomon JA, Ezzati M, Danaei G. A novel risk score to predict cardiovascular disease risk in national populations (Globorisk): a pooled analysis of prospective cohorts and health examination surveys.. Lancet Diabetes Endocrinol. 2015 May;3(5):339-55. doi: 10.1016/S2213-8587(15)00081-9. Epub 2015 Mar 26. ISSN:2213-8595. doi: 10.1016/S2213-8587(15)00081-9 236. Castillo Y, Aguilar Salinas CA. Los costos de la hipoglucemia en America Latina. Revista ALAD 2015;23:12-13 ISSN: 2248-6518. http://www.revistaalad.com/files/alad-v5n1_012-014.pdf 237. Huerta-Chagoya A, Vázquez-Cárdenas P, Moreno-Macías H, Tapia-Maruri L, Rodríguez-Guillén R, López-Vite E, García-Escalante G, Escobedo-Aguirre F, Parra-Covarrubias A, Cordero-Brieño R, Manzo-Carrillo L, Zacarías-Castillo R, Vargas-García C, Aguilar-Salinas C, Tusié-Luna T. Genetic determinants for gestational diabetes mellitus and related metabolic traits in mexican women.PLoS One. 2015 May 14;10(5):e0126408. ISSN: 1932-6203. doi: 10.1371/journal.pone.0126408. eCollection 2015. 238. Flores-Castillo C, Zamora-Pérez JÁ, Carreón-Torres E, Arzola-Paniagua A, Aguilar-Salinas C, López- Olmos V, Fragoso JM, Luna-Luna M, Rodríguez-Pérez JM, Franco M, Vargas-Alarcón G, Pérez-Méndez Ó.Atorvastatin and fenofibrate combination induces the predominance of the large HDL subclasses and increased apo AI fractional catabolic rates in New Zealand white rabbits with exogenous hypercholesterolemia. Fundam Clin Pharmacol. 2015 Aug;29(4):362-70. ISSN: 1472-8206 doi: 10.1111/fcp.12125. Epub 2015 Jun 5.. IS: 1472-8206 239. NCD Risk Factor Collaboration (NCD-RisC Aguilar Salinas entre otros 434 autores) Effects of diabetes defi nition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331 288 participants. Lancet Diabetes Endocrinol. 2015 Aug;3(8):624- 37. ISSN: 2213-8595 doi: 10.1016/S2213-8587(15)00129-1. Epub 2015 Jun 21. doi: 10.1016/S2213- 8587(15)00129- 240. Gutiérrez-Vidal R, Vega-Badillo J, Reyes-Fermín LM, Hernández-Pérez HA, Sánchez-Muñoz F, López- Álvarez GS, Larrieta-Carrasco E, Fernández-Silva I, Méndez-Sánchez N, Tovar AR, Villamil-Ramírez H, Mejía-Domínguez AM, Villarreal-Molina T, Hernández-Pando R, Campos-Pérez F,Aguilar-Salinas CA, Canizales-Quinteros S. SFRP5 hepatic expression is associated with non-alcoholic liver disease in morbidly obese women. Ann Hepatol. 2015 Sep-Oct;14(5):666-74. ISSN: 1665- 2681.http://www.annalsofhepatology.com/revista/numeros/2015/HP155-07- SFRP5%20(FF_280715m)_PROTEGIDO.pdf 241. Yulino Castillo-Núñez, Carlos A. Aguilar-Salinas.Medición de la resistencia a la insulina en la práctica clínica. Revista ALAD 2015;5:7-8 ISSN: 2248-6518. http://www.revistaalad.com/files/alad-v5n2_064- 065.pdf 242. Carlos A. Aguilar-Salinas, Yulino Castillo-Núñez El fortalecimiento de la Revista ALAD: desatando el nudo de la indexación. Revista ALAD 2015;5:5-6 ISSN: 2248-6518. http://www.revistaalad.com/files/alad-v5n2_064-065.pdf 243. Carlos A. Aguilar-Salinas Comentarios a artículos de actualidad en diabetes. Revista ALAD 2015;5:26- 28 ISSN: 2248-6518. http://www.revistaalad.com/files/alad-v5n2_118-121.pdf 244. Zinman B, Wanner C, Lachin JM, Fitchett D, Bluhmki E, Hantel S, Mattheus M, Devins T, Johansen OE, Woerle HJ, Broedl UC, Inzucchi SE; EMPA-REG OUTCOME Investigators (Aguilar Salinas CA entre otros). Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes. N Engl J Med. 2015 Nov 26;373(22):2117-28. ISSN:1533-4406. doi: 10.1056/NEJMoa1504720. 245. Vallejo-Vaz AJ, Kondapally Seshasai SR, Cole D, Hovingh GK, Kastelein JJ, Mata P, Raal FJ, Santos RD, Soran H, Watts GF, Abifadel M, Aguilar-Salinas CA, Akram A, Alnouri F, Alonso R, Al-Rasadi K, Banach M, Bogsrud MP, Bourbon M, Bruckert E, Car J, Corral P, Descamps O, Dieplinger H, Durst R, Freiberger T, Gaspar IM, Genest J, Harada-Shiba M, Jiang L, Kayikcioglu M, Lam CS, Latkovskis G, Laufs U, Liberopoulos E, Nilsson L, Nordestgaard BG, O'Donoghue JM, Sahebkar A, Schunkert H, Shehab A, Stoll M, Su TC, Susekov A, Widén E, Catapano AL, Ray KK. FAMILIAL HYPERCHOLESTEROLAEMIA: A GLOBAL CALL TO ARMS.Atherosclerosis. 2015 Sep 18;243(1):257-259. ISSN: 1879-1484. doi: 10.1016/j.atherosclerosis.2015.09.021 246. Aguilar N, Almeda P, Aguilar Salinas Carlos A, Uribe M, Mendez N. The role of bariatric surgery in the management of nonalcoholic fatty liver disease and metabolic syndrome. Metabolism. 2016 Aug;65(8):1196-207doi: 10.1016/j.metabol.2015.09.004. ISSN:1532-8600. 247. Alarcón-Riquelme ME, Ziegler JT, Molineros J, Howard TD, Moreno-Estrada A, Sánchez-Rodríguez E, Ainsworth HC, Ortiz-Tello P, Comeau ME, Rasmussen A, Kelly JA, Adler A, Acevedo-Vázquez E, Cucho JM, la Torre IG, Cardiel MH, Miranda P, Catoggio L, Maradiaga-Ceceña M, Gaffney P, Vyse T, Criswell LA, Tsao BP, Sivils KL, Bae SC, James JA, Kimberly R, Kaufman K, Harley JB, Esquivel-Valerio J, Moctezuma JF, García MA, Berbotto G, Babini A, Scherbarth H, Toloza S, Baca V, Nath SK, Aguilar Salinas CA, Orozco L, Tusié-Luna T, Zidovetzki R, Pons-Estel BA, Langefeld CD, Jacob CO. GWAS in an Amerindian ancestry population reveals novel systemic lupus erythematosus risk loci and the role of European admixture. ARTHRITIS RHEUMATOL 2016 Apr;68(4):932-943. ISSN:2326-5205. doi: 10.1002/art.39504 248. Rodríguez-Ortiz D, Reyes-Pérez A, León P, Sánchez H1, Mosti M1, Aguilar-Salinas CA2, Velázquez- Fernández D1, Herrera MF3. Assessment of two different diagnostic guidelines criteria (National Cholesterol Education Adult Treatment Panel III [ATP III] and International Diabetes Federation [IDF]) for the evaluation of metabolic syndrome remission in a longitudinal cohort of patients undergoing Roux-en-Y gastric bypass. Surgery. 2016 Apr;159(4):1121-8 pii: S0039-6060(15)00962-9. doi: 10.1016/j.surg.2015.11.01. PMID: 26747228. ISSN:1532-7361 doi: 10.1016/j.surg.2015.11.015 249. F.M. Del Razo, D. Elías-López, L.E. Guillen, R. Mehta, Luisa Safar-Boueri, J.R. Clemow, Verónica Espinosa, M.A. Melgarejo Carlos A. Aguilar-Salinas. Clinical, anthropometric, and biochemical factors associated with carotid intima media thickness in mexican subjects with hyper- or hypoalphalipoproteinemia. Revista Mexicana de Endocrinología Metabolismo & Nutrición 2015 2015; 3:118-27 ISSN: 2462-4144. http://www.revistadeendocrinologia.com/files/endocrinologia_2015_2_3_118-127.pdf 250. Ruy David Arjona-Villicaña, Marco Antonio Melgarejo-Hernández, Jimena Hernández-Alarcón, Blanca Estela López-Contreras, Roopa Mehta, Samuel Canizales-Quinteros, María Teresa Tusié-Luna and Carlos A. Aguilar-Salinas The ATP-binding cassette transporter a1 R230C variant does not modify the weight loss response to hypocaloric diet Revista Mexicana de Endocrinología Metabolismo & Nutrición 2015 2015; 3:128-37 ISSN: 2462-4144 http://www.revistadeendocrinologia.com/files/endocrinologia_2015_2_3_128-137.pdf 251. Roopa Mehta, Enrique Reyes-Rodriguez, Ana Carmen Guerrero-Diaz, Ivette Cruz-Bautista and Carlos A. Aguilar-Salinas. Comparing treatment targets in familial combined hiperlipidemia. Revista Mexicana de Endocrinología Metabolismo & Nutrición 2015 2015; 3:138-49. (no en sistema investigadores) ISSN: 2462-4144 http://www.revistadeendocrinologia.com/files/endocrinologia_2015_2_3_138-149.pdf 252. Rita A. Gómez-Diaz and Carlos A. Aguilar-Salinas. Controversial issues of the (AHA/ACC) Cholesterol Guidelines: the use and abuse of evidence-based medicine Revista Mexicana de Endocrinología Metabolismo & Nutrición 2015; 3:150-56 (no en sistema investigadores) ISSN: 2462-4144 Conacyt http://www.revistadeendocrinologia.com/files/endocrinologia_2015_2_3_150-156.pdf 253. Castillo Y, Aguilar Salinas CA. Grupos de ayuda mutua y la investigación cualitativa en diabetes Revista ALAD 2015;5:197-200 ISSN: 2248-6518 254. Daniel Elías-López, Ana L. Elías-López, Roopa P. Mehta, Carlos A. Aguilar Salinas. Impacto del vínculo diabetes mellitus-tuberculosis en la salud pública de México. Revista ALAD 2015;5 (3):161-171 ISSN: 2248-6518 http://www.revistaalad.com/files/alad-v5n3_161-171.pdf 255. Pallares R, Aguilar Salinas CA, Cruz Bautista I, Del Bosque Plata L. Metabolomics in Diabetes: a review. Ann Med 2016 Feb;48(1-2):89-102. PMID:26883715 ISSN:1365-2060. doi: 10.3109/07853890.2015.1137630 256. Vega Badillo H, Gutierrez Vidal R, Villamil H, Moran S, Hernandez Perez H, Villarreal MT, Mendez N,Aguilar Salinas CA, Tovar AR, Canizales S. Hepatic miR-33a/miR-144 and their target gene ABCA1 are associated with steatohepatitis in morbidly obese subjects. Liver Int. 2016 Sep;36(9):1383-91. ISSN:1478-3223 doi: 10.1111/liv.13109 257. Castillo Y, Aguilar Salinas CA. Creencias sobre diabetes: rompiendo barreras en el manejo de la diabetes centrado en el paciente. Revista ALAD 2016;6:5-6 ISSN: 2248-6518. http://www.revistaalad.com/files/alad-v6n1_005-006.pdf 258. Liliana Muñoz Hernández, Carlos A. Aguilar-Salinas. Lipoproteínas de alta densidad y su papel en la diabetes mellitus tipo 2. ¿Un marcador diagnóstico temprano subestimado?. Revista ALAD 2016;6:41-54. ISSN:0140-6736 http://www.revistaalad.com/files/alad-v6n1_041-054.pdf 259. Omar Y. Bello-Chavolla, Carlos A. Aguilar-Salinas. Comentarios a artículos de actualidad en diabetes. Revista ALAD 2016;6:55-59. ISSN:0140-6736. http://www.revistaalad.com/files/alad-v6n1_055- 061.pdf 260. Valencia-Flores M, Bliwise D, Santiago-Ayala V, Resendiz-Garcia M, Castano-Meneses A, Meza- Vargas MS, Mendoza A, Orea-Tejeda A, Garcia-Ramos G, Aguilar Salinas CA, Mokhlesi B. Intermittent hypoxemia and sleep fragmentation: associations with daytime alertness in obese sleep apnea patients living at moderate altitude. Sleep Medicine 2016; 20:103-109. ISSN:1389-9457 doi: 10.1016/j.sleep.2016.01.002 261. NCD Risk Factor Collaboration (NCD-RisC) (Aguilar Salinas CA entre otros). The weight of the world – trends in adult body mass index in 200 countries since 1975: pooled analysis of 1,617 population- based measurement studies with 18.8 million participants. Lancet. 2016 Apr 2;387(10026):1377-96. ISSN: 0140-6736. doi: 10.1016/S0140-6736(16)30054-X 262. 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Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults.. Lancet. 2017 Oct 10. Lancet. 2017 Dec 16;390(10113):2627-2642.

299. Márquez-Luna C, Loh PR; South Asian Type 2 Diabetes (SAT2D) Consortium; SIGMA Type 2 Diabetes Consortium (Aguilar Salinas CA entre otros), Price AL. Multiethnic polygenic risk scores improve risk prediction in diverse populations.Genet Epidemiol. 2017 Nov 7. 2017 Dec;41(8):811- 823. doi: 10.1002/gepi.22083. [Epub ahead of print]

300. Piaggi P, Masindova I, Muller YL, Mercader J, Wiessner GB, Chen P; SIGMA Type 2 Diabetes Consortium (Aguilar Salinas CA entre otros), Kobes S, Hsueh WC, Mongalo M, Knowler WC, Krakoff J, Hanson RL, Bogardus C, Baier LJ.A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in GPR158 Associated With Reduced Energy Expenditure in American Indians. Diabetes. 2017 Aug;66(8):2284-2295. doi: 10.2337/db16-1565. Epub 2017 May 5. 301. Jiménez IU, Díaz-Díaz E, Castro JS, Ramos JP, León MC, Alvarado Ríos JA, Auriostigue Bautista JC, Correa-Rotter R, Aguilar Salinas CA, Larrea F. Circulating Concentrations of Advanced Glycation end Products, its Association With the Development of Diabetes Mellitus. Arch Med Res. 2017 May;48(4):360-369. doi: 10.1016/j.arcmed.2017.07.001. IS - 0188-4409

302. Castrejón-Pérez RC, Aguilar-Salinas CA, Gutiérrez-Robledo LM, Cesari M, Pérez-Zepeda MU. Frailty, diabetes, and the convergence of chronic disease in an age-related condition: a population-based nationwide cross-sectional analysis of the Mexican nutrition and health survey. Aging Clin Exp Res. 2017 Nov 27. doi: 10.1007/s40520-017-0852-2

303. Aguilar-Salinas CA1, Sevilla González MDR2, Tusie-Luna MT2. Searching for the Causal Variants of the Association Between Hypertriglyceridemia and the Genome-Wide Association Studies-Derived Signals? Take a Look in the Native American Populations. Circ Cardiovasc Genet. 2017 Dec;10(6). pii: e002010-12. doi: 10.1161/CIRCGENETICS.117.002010.

304. Rosalba Rojas-Martínez, PhD,(1) Ana Basto-Abreu, MSc,(1) Carlos A Aguilar-Salinas, PhD,(2) Emiliano Zárate-Rojas, Mr,(2) Salvador Villalpando, PhD,(3) Tonatiuh Barrientos-Gutiérrez, PhD. Prevalencia de diabetes por diagnóstico médico previo en México. Salud Publica Mex 2018:60.

305. B. E. López-Contreras1 , S. Morán-Ramos1,2, R. Villarruel-Vázquez1 , L. Macías-Kauffer1 , H. Villamil- Ramírez1 , P. León-Mimila1 , J. Vega-Badillo1 , F. Sánchez-Muñoz3 , L. E. Llanos-Moreno1 , A. Canizalez-Román4 , B. del Río-Navarro5 , I. Ibarra-González6,7, M. Vela-Amieva7 , T. Villarreal- Molina8 , A. Ochoa-Leyva1,9, C. A. Aguilar-Salinas10 and S. Canizales-Quinteros1. Composition of gut microbiota in obese and normalweight Mexican school-age children and its association with metabolic traits. Pediatric Obesity 2018 doi:10.1111/ijpo.12262

306. Sevilla-González MDR, Quintana-Mendoza BM, Aguilar-Salinas CA. Interaction Between Depression, Obesity, and Type 2 Diabetes: A Complex Picture.Arch Med Res. 2018 Feb 22. pii: S0188- 4409(18)30034-1. doi: 10.1016/j.arcmed.2018.02.004

307. Bello-Chavolla OY, Almeda-Valdes P, Gomez-Velasco D, Viveros-Ruiz T, Cruz-Bautista I, Romo-Romo A, Sánchez-Lázaro D, Meza-Oviedo D, Vargas-Vazquez A, Arellano Campos O, Sevilla-González MDR, Martagón AJ, Muñoz Hernández L, Mehta RP, Caballeros-Barragán CR, Aguilar-Salinas C. METS-IR, a novel score to evaluate insulin sensitivity, is predictive of visceral adiposity and incident type 2 diabetes. Eur J Endocrinol. 2018 Mar 13. pii: EJE-17-0883. doi: 10.1530/EJE-17-0883.

308. Romero-Díaz J, Acosta-Hernández RI, Criales-Vera S, Kimura-Hayama E, Domínguez-Quintana M, Morán-Contla R, Núñez-Alvarez C, Lara-Reyes P, Aguilar-Salinas C, Sánchez-Guerrero J. Asymptomatic Coronary Artery Calcifications in Men with Systemic Lupus Erythematosus. J Rheumatol. 2018 Mar 15. pii: jrheum.170330. doi: 10.3899/jrheum.170330

309. NCD Risk Factor Collaboration (NCD-RisC, Aguilar Salinas CA entre otros) . Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants. Int J Epidemiol. 2018 Mar 19. doi: 10.1093/ije/dyy016. [Epub ahead of print]. ISSN; 0300-5771

310. Rojas-Martínez R, Basto-Abreu A, Aguilar-Salinas CA, Zárate-Rojas E, Villalpando S, Barrientos- Gutiérrez T. Prevalence of previously diagnosed diabetes mellitus in Mexico.] Salud Publica Mex. 2018 May-Jun;60(3):224-232. doi: 10.21149/8566. Spanish. 311. Danchin N, Almahmeed W, Al-Rasadi K, Azuri J, Berrah A, Cuneo CA, Karpov Y, Kaul U, Kayıkçıoğlu M, Mitchenko O, Ruiz AJ, Aguilar Salinas CA, Santos RD, Mercier F, Blom D; ICLPS Investigators.Achievement of low-density lipoprotein cholesterol goals in 18 countries outside Western Europe: The International ChoLesterol management Practice Study (ICLPS).Eur J Prev Cardiol. 2018 Jan 1:2047487318777079. doi: 10.1177/2047487318777079. [Epub ahead of print]PMID:29771156 312. Lim LL, Lau ESH, Kong APS, Davies MJ, Levitt NS, Eliasson B, Aguilar-Salinas CA, Ning G, Seino Y, So WY, McGill M, Ogle GD, Orchard TJ, Clarke P, Holman RR, Gregg EW, Gagliardino JJ, Chan JCN. Aspects of Multicomponent Integrated Care Promote Sustained Improvement in Surrogate Clinical Outcomes: A Systematic Review and Meta-analysis. Diabetes Care. 2018 Jun;41(6):1312-1320. doi: 10.2337/dc17-2010. Review. PMID:29784698. ISSN: 0149-5992 313. Martagón AJ, Bello-Chavolla OY, Arellano-Campos O, Almeda-Valdés P, Walford GA, Cruz-Bautista I, Gómez-Velasco DV, Mehta R, Muñoz-Hernández L, Sevilla-González M, Viveros-Ruiz TL, Ordoñez- Sánchez ML, Rodríguez-Guillen R, Florez JC, Tusié-Luna MT, Aguilar-Salinas CA; Slim Initiative in Genomic Medicine for the Americas (SIGMA) Type 2 Diabetes Consortium. Mexican Carriers of the HNF1A p.E508K Variant Do Not Experience an Enhanced Response to Sulfonylureas. Diabetes Care. 2018 May 29. pii: dc180384. doi: 10.2337/dc18-0384. [Epub ahead of print]. IS 0149-5992 314. Oralia Nájera-Medina Carmen P Rodríguez-López, MBE; Cristina González-Torres, PhD; Carlos A Aguilar-Salinas, PhD. Peripheral lymphocytes, obesity, and metabolic syndrome in young adults: an immunometabolism study. Metab Syndr Relat Disord. 2018 Jun 29. doi: 10.1089/met.2018.0005. 315. Magdalena Sevilla, Carlos Aguilar-Salinas, Liliana Muñoz-Hernández, Paloma Almeda-Valdes, Roopa Mehta, Rafael Zubirán, Omar Bello-Chavolla, Donaji Gomez-Velasco, Arsenio Vargas-Vazquez, Tannia Viveros-Ruiz, Alexandro Martagon-Rosado, Ivette Cruz-Bautista. Identification of a Threshold to Discriminate Fasting Hypertriglyceridemia with Postprandial Values Lipids Health Dis. 2018 Jul 18;17(1):156. doi: 10.1186/s12944-018-0803-8. 316. Janneth Bermeo Cabrera, Paloma Almeda-Valdes, Josefa Riofrio Palacios, Carlos A. Aguilar-Salinas and Roopa Mehta. Factors associated with insulin adherence in patients with type 2 diabetes J Diabetes Res. 2018 Jul 15;2018:3190849. doi: 10.1155/2018/3190849. eCollection 201 317. Simon Barquera; Dean Schillinger; Carlos A. Aguilar Salinas; Luis A. Rodriguez; Cesar Hernandez- Alcaraz; Jaime Sepúlveda-Amor. Type 2 Diabetes in People of Mexican Origin: The Need for Collaborative Research and Action on Both Sides of the US-Mexico Border Global Health. 2018 Aug 22;14(1):84. doi: 10.1186/s12992-018-0390-5 318. Kaufer-Horwitz M, Tolentino-Mayo L, Jáuregui A, Sánchez-Bazán K, Bourges H, Martínez S, Perichart O, Rojas-Russell M, Moreno L, Hunot C, Nava E, Ríos-Cortázar V, Palos-Lucio G, González L, González- de Cossio T, Pérez M, Borja Aburto VH, González A, Apolinar E, Pale LE, Colín E, Barriguete A, López O, López S, Aguilar-Salinas CA, Hernández-Ávila M, Martínez-Duncker D, de León F, Kershenobich D, Rivera J, Barquera S. A front-of-pack labelling system for food and beverages for Mexico: a strategy of healthy decision-making. Salud Publica Mex. 2018 Jul-Ago;60(4):479-486. doi: 10.21149/9615. Spanish 319. Roopa Mehta, Enrique Reyes-Rodríguez,, Omar Yaxmehen Bello-Chavolla, Ana Carmen Guerrero Diaz, Arsenio Vargas-Vázquez, Ivette Cruz-Bautista, Carlos A. Aguilar-Salinas.. Performance of LDL-C calculated with Martin’s formula compared to the Friedewald equation in Familial Combined Hyperlipidemia. Atherosclerosis. 2018 Jun 21. pii: S0021-9150(18)31180-8. doi: 10.1016/j.atherosclerosis.2018.06.868. [Epub ahead of print] 320. Muñoz-Hernandez L, Ortiz-Bautista RJ, Lozano-Arvizu F, Brito-Córdova G, Saucedo S, Pérez-Méndez O, Zentella-Dehesa A, Lhomme M, Lesnik P, Chapman MJ, Aguilar Salinas CA, Kontush A. Cholesterol efflux capacity of total HDL particles and its subclasses 2b and 3C is unaltered by atorvastatin in patients with type 2 diabetes. Atherosclerosis 2018 Aug 24;277:72-79. doi: 10.1016/j.atherosclerosis.2018.08.027. 321. Isabel Ibarra-González, Ivette Cruz-Bautista, Omar Yaxmehen Bello-Chavolla, Marcela Vela-Amieva, Rigoberto Pallares-Méndez, Diana Ruiz de Santiago Y Nevarez, María Fernanda Salas-Tapia, Ximena Rosas-Flota, Mayela González-Acevedo, Adriana Palacios-Peñaloza, Mario Morales–Esponda, Carlos Alberto Aguilar-Salinas, Laura Del Bosque-Plata, Optimization of kidney dysfunction prediction in diabetic kidney disease using targeted metabolomics Acta Diabetol. 2018 Sep 1. doi: 10.1007/s00592-018-1213-0

Papers accepted for publication 1. Mehta R, Martagon AJ, Galan Ramirez GA, Gonzalez Retana G, Martinez-Beltran M, Vargas Vazquez A, Vazquez-Cardenas A, Aguilar-Salinas CA.Familial hypercholesterolemia in Mexico: the development of the Mexican National Registry. Atherosclerosis 2018.

2. Alonso Romo-Romo, Carlos A. Aguilar-Salinas, Griselda X. Brito-Córdova, Rita A. Gómez-Díaz, Paloma Almeda-Valdés.Sucralose decreases insulin sensitivity in healthy subjects: a randomized controlled trial. Am J Clin Nutrition 2018

3. OVERVIEW OF THE CURRENT STATUS OF FAMILIAL HYPERCHOLESTEROLAEMIA CARE IN OVER 60 COUNTRIES - THE EAS FAMILIAL HYPERCHOLESTEROLAEMIA STUDIES COLLABORATION (FHSC) Atherosclerosis

Papers sent for publication 1.Albino Barraza-Villarreal, Maria C Escamilla-Núñez, MSc; Leticia Hernández-Cadena, ScD; Ana L Barbosa-Sánchez, MSc; Isabelle Romieu, ScD; Dan B Barr, PhD; Maria E Gonsebatt, PhD; Rogelio Pérez- Padilla, PhD; Carlos Aguilar-Salinas, PhD; Victor H Borja-Aburto. Exposure indices for phthalates and BPA and their potential use in epidemiological studies Environmental Research:

2.Márquez-López Ziomara N, Muñoz-Hernandez L Liliana, Lozano-Arvizu Francisco J, Bello-Chavolla Omar Y, Aguilar-Salinas Carlos A.Intermittent fasting as part of the management for obesity and T2DM: Beyond weight loss Obesity

3. Rodriguez Flores, Marcela; Cruz Soto , Ruth; Vázquez Velázquez, Verónica; Soriano Cortés, Ruth; Aguilar Salinas, Carlos A; García García, Eduardo, "Continuous glucose monitoring in the management of patients after gastric bypass. Two case reports." Clinical Case Reports.

4. Teresa Villarreal-Molina, Francisco J. Flores-Murrieta, Hugo Villamil-Ramírez, Blanca E. López- Contreras, Mrs. Rosalinda Posadas-Sánchez, Dr Acuña-Alonzo Víctor, Dr Rafael Velázquez-Cruz, Dr Lina M Barranco-Garduño, Dr Romero-Hidalgo Sandra, Dr. Carlos Alberto Aguilar Salinas, Dr Gilberto Vargas, Dr Paola Viridiana León Mimila, Dr Blanca Del Rio-Navarro, Dr. Leonor Jacobo-Albavera, Dr Miriam del C. Carrasco-Portugal, Dr. Sofia Moran-Ramos, Dr Carlos Posadas-Romero, Dr Cecilia Fernández del Valle- Laisequilla, Dr Juan G. Reyes-García, Dr Luis Macias, Dr. Samuel Canizales-Quintero. “Genetic Contributors to Serum Uric Acid Levels in Mexicans and their Effect on Premature Coronary Artery Disease Int J Cardiology

6. Goncalo Abecasis, Carlos A Aguilar-Salinas, David Altshuler, et al. Genetic discovery and translational decision support from exome sequencing of 20,791 type 2 diabetes cases and 24,440 controls from five ancestries" (reference number: 2018-06-07592) Nature

7.Paloma Almeda-Valdes, Donaji V. Gómez Velasco, Olimpia Arellano Campos, Omar Yaxmehen Bello- Chavolla, Magdalena del Rocío Sevilla-González, Tannia Viveros Ruiz, Alexandro J. Martagón Rosado, Claudia J. Bautista, Liliana Muñoz Hernandez, Ivette Cruz-Bautista, Hortensia Moreno-Macias, Alicia Huerta-Chagoya, Karen Guadalupe Rodríguez-Álvarez, Geoffrey A. Walford, Suzanne B. R. Jacobs, Luz E. Guillen Pineda, Ma. Luisa Ordoñez-Sánchez, Ernesto Roldan-Valadez, Joaquín Azpiroz, Jannette Furuzawa-Carballeda, Patricia Clark, Miguel F. Herrera-Hernández, Elena Zambrano, Jose C. Florez, María Teresa Tusié Luna, Carlos A. Aguilar-Salinas The SLC16A11 risk haplotype is associated with decreased insulin action, higher serum hepatic transaminases and large-sized adipocytes Journal of Clinical Endocrinology and Metabolism

8.Sifuentes-Osornio, Jose; Torres-Gonzalez, Pedro; Tamez-Torres, Karla; Almeda-Valdes, Paloma; Cervera-Hernandez, Miguel; Bobadilla-del Valle, Miriam; Araujo-Melendez, Miguel; Castelan-Garcia, Carlos; Aguilar-Salinas, Carlos; Garcia-Garcia, Lourdes; Ponce-de-Leon, Alfredo. Cumulative type 2 diabetes mellitus chronic complications are associated with active tuberculosis. A case-control hospital-based study. Lung

9. David W Clark , Yukinori Okada,Kristjan H S Moore, Dan Mason, Nicola Pirastu, Ilaria Gandin7,8, Hannele Mattsson9,10, Catriona L K Barnes1 , Kuang Lin11, Jing Hua Zhao12, Patrick Deelen13, Rebecca Rohde14, Claudia Schurmann15, Xiuqing Guo16 5 , Franco Giulianini17, Weihua Zhang18,19, Carolina Medina-Gomez20,21,22, Robert Karlsson23, Yanchun Bao24, Traci M Bartz25, Clemens Baumbach26, Ginevra Biino27, Matthew J Bixley28, Marco Brumat8 , Jin-Fang Chai29, Tanguy Corre30,31,32, Diana L Cousminer33,34, Annelot M Dekker35, David A Eccles36,37, Kristel R van Eijk35, Christian Fuchsberger38, He Gao18,39, Marine Germain40,41, Scott D Gordon42, Hugoline G de Haan43, Sarah E Harris44,45, Edith Hofer46,47 10 , Alicia Huerta-Chagoya48, Catherine Igartua49, Iris E Jansen50,51, Yucheng Jia16, Tim Kacprowski52,53, Torgny Karlsson54, Marcus E Kleber55, Shengchao Alfred Li56, Ruifang LiGao43, Koichi Matsuda57, Karina Meidtner58,59, Weihua Meng60, May E Montasser61,62, Peter J van der Most63, Matthias Munz64,65,66,67, Teresa Nutile68, Teemu Palviainen69, Rashmi B Prasad70, Tallapragada Divya Sri Priyanka71, Federica Rizzi72,73, Erika Salvi73,74, Bishwa R Sapkota75 15 , Daniel Shriner76, Line Skotte77, Melissa C Smart24, Albert Vernon Smith78,79, Ashley van der Spek21, Cassandra N Spracklen80, Rona J Strawbridge81,82, Salman M Tajuddin83, Stella Trompet84,85, Constance Turman86,87, Niek Verweij88, Clara Viberti89, Lihua Wang90, Helen R Warren91,92, Robyn E Wooton93,94, Lisa R Yanek95, Jie Yao16, Noha A Yousri96,97, Wei Zhao98, Adebowale A Adeyemo76, Saima Afaq18, Carlos Alberto Aguilar-Salinas99, Masato Akiyama3,100 20 , Matthew L Albert101,102,103,104, Matthew A Allison105, Maris Alver106, Tin Aung107,108,109, Fereidoun Azizi110, Amy R Bentley76, Heiner Boeing111, Eric Boerwinkle112, Judith B Borja113, Gert J de Borst114, Erwin P Bottinger15,115, Linda Broer20, Harry Campbell1 , Stephen Chanock116, Miao-Li Chee107, Guanjie Chen76, Yii-Der I Chen16, Zhengming Chen11, Yen-Feng Chiu117, Massimiliano Cocca118, Francis S Collins119, Maria Pina Concas118, Janie Corley44,120 25 , Giovanni Cugliari89, Rob M van Dam29,121,122, Anna Damulina46, Maryam S Daneshpour123, Felix R Day12, Graciela E Delgado55, Klodian Dhana21,122, Alexander S F Doney124, Marcus Dörr125,126, Ayo P Doumatey76, Nduna Dzimiri127, S Sunna Ebenesersdóttir5,128, Joshua Elliott18, Paul Elliott18,39,129,130,131, Ralf Ewert125, Janine F Felix21,22,132, Krista Fischer106, Barry I Freedman133, Giorgia Girotto8,134, Anuj Goel135,136, Martin Gögele38, Mark O Goodarzi137, Mariaelisa Graff14 30 , Einat Granot-Hershkovitz138, Francine Grodstein86, Simonetta Guarrera89, Daniel F Gudbjartsson5,139, Kamran Guity123, Bjarni Gunnarsson5 , Yu Guo140, Saskia P Hagenaars44,120,141, Christopher A Haiman142, Avner Halevy138, Tamara B Harris83, Mehdi Hedayati123, David A van Heel143, Makoto Hirata144, Imo Höfer145, Chao Agnes Hsiung146, Jinyan Huang147, Yi-Jen Hung148,149, M Arfan Ikram21, Anuradha Jagadeesan5,128, Pekka Jousilahti150 35 , Yoichiro Kamatani3,151, Masahiro Kanai2,3,152, Nicola D Kerrison12, Thorsten Kessler153, Kay-Tee Khaw154, Chiea Chuen Khor107,155, Dominique P V de Kleijn114, Woon-Puay Koh29,156, Ivana Kolcic157, Peter Kraft122, Bernhard K Krämer55, Zoltán Kutalik31,32, Johanna Kuusisto158,159, Claudia Langenberg12, Lenore J Launer83, Deborah A Lawlor93,160,161, I-Te Lee162,163,164, WenJane Lee165, Markus M Lerch166, Liming Li167, Jianjun Liu121,155, Marie Loh18,168,169 40 , Stephanie J London170, Stephanie Loomis171, Yingchang Lu15, Jian'an Luan12, Reedik Mägi106, Ani W Manichaikul172, Paolo Manunta173, Gísli Másson5 , Nana Matoba3 , Xue W Mei11, Christa Meisinger174, Thomas Meitinger175,176,177, Massimo Mezzavilla134, Lili Milani178, Iona Y Millwood11, Yukihide Momozawa179, Amy Moore116, Pierre-Emmanuel Morange180,181, Hortensia Moreno-Macías182, Trevor A Mori183, Alanna C Morrison184, Taulant Muka21 45 , Submitted Manuscript: Confidential 2 Yoshinori Murakami185, Alison D Murray186, Renée de Mutsert43, Josyf C Mychaleckyj172, Mike A Nalls187,188, Matthias Nauck126,189, Ilja M Nolte63, Ken K Ong12,190, Lorena Orozco191, Sandosh Padmanabhan192, Gunnar Pálsson5 , James S Pankow193, Cristian Pattaro38, Alison Pattie120, Ozren Polasek157,194, Neil Poulter195,196, Peter P Pramstaller38, Lluis Quintana- Murci197,198,199, Katri Räikkönen200, Sarju Ralhan201, Dabeeru C Rao202, Wouter van Rheenen35 5 , Stephen S Rich172, Paul M Ridker17,203, Cornelius A Rietveld204,205, Antonietta Robino118, Frank J A van Rooij21, Daniela Ruggiero68,206, Yasaman Saba207, Charumathi Sabanayagam107,108,109, Maria Sabater-Lleal82,208, Cinzia Felicita Sala209, Veikko Salomaa210, Kevin Sandow16, Helena Schmidt211, Laura J Scott212, William R Scott18, Bahareh Sedaghati-Khayat123, Bengt Sennblad82,213, Jessica van Setten214, Peter J Sever195, Wayne H-H Sheu162,215,216,217, Yuan Shi107 10 , Smeeta Shrestha71,218, Sharvari Rahul Shukla219,220, Jon K Sigurdsson5 , Timo Tonis Sikka106, Jai Rup Singh221, Blair H Smith222, Alena Stančáková 158, Alice Stanton223, John M Starr44,224, Lilja Stefansdottir5 , Leon Straker225, Patrick Sulem5 , Gardar Sveinbjornsson5 , Morris A Swertz13, Adele M Taylor120, Kent D Taylor16, Natalie Terzikhan21,226, Yih-Chung Tham107,108, Gudmar Thorleifsson5 , Unnur Thorsteinsdottir5,79, Annika Tillander23, Russell P Tracy227 15 , Teresa TusiéLuna228,229, Ioanna Tzoulaki18,39,230, Simona Vaccargiu231, Jagadish Vangipurapu158, Jan H Veldink35, Veronique Vitart232, Uwe Völker52,126, Eero Vuoksimaa233, Salma M Wakil127, Melanie Waldenberger26, Gurpreet S Wander234, Ya Xing Wang235, Nicholas J Wareham12, Sarah Wild236, Chittaranjan S Yajnik237, Jian-Min Yuan238, Lingyao Zeng153, Liang Zhang107, Jie Zhou76, The SIGMA T2D consortium239, Najaf Amin21, Folkert W Asselbergs240,241,242,243 20 , Stephan J L Bakker244, Diane M Becker95, Lehne Benjamin18, David A Bennett245,246, Leonard H van den Berg35, Sonja I Berndt116, Lawrence F Bielak98, Murielle Bochud31, Mike Boehnke212, Claude Bouchard247, Jonathan P Bradfield248,249, Jennifer A Brody250, Archie Campbell45, Shai Carmi138, Mark J Caulfield91,92, David Cesarini251,252, John C Chambers18,19,39,253,254, Giriraj Ratan Chandak71, Ching-Yu Cheng107,108,109, Marina Ciullo68,206, Marilyn Cornelis255 25 , Daniele Cusi73,256,257, George Davey-Smith93,161, Ian Deary44,120, Rajkumar Dorajoo155, Cornelia M van Duijn21, David Ellinghaus258, Jeanette Erdmann259, Johan G Eriksson260,261,262,263,264, Evangelos Evangelou18,230, Michele K Evans83, Jessica D Faul265, Bjarke Feenstra77, Mary Feitosa90, Sylvain Foisy266, Andre Franke258, Yechiel Friedlander138, Paolo Gasparini8,134, Christian Gieger26,59, Clicerio Gonzalez267, Philippe Goyette266, Struan F A Grant34,248,268, Lyn R Griffiths36 30 , Leif Groop69,70, Vilmundur Gudnason78,79, Ulf Gyllensten54, Hakon Hakonarson248,268, Anders Hamsten269, Pim van der Harst88, Chew-Kiat Heng270,271, Andrew A Hicks38, Hagit Hochner138, Heikki Huikuri272, Steven C Hunt96,273, Vincent W V Jaddoe21,22,132, Philip L De Jager274,275, Magnus Johannesson276, Åsa Johansson54 , Jost B Jonas235,277, J Wouter Jukema84, Juhani Junttila272, Jaakko Kaprio69,278, Sharon LR Kardia98, Meena Kumari24, Markku Laakso158,159 35 , Sander W van der Laan279, Jari Lahti200,280, Matthias Laudes281, Rodney A Lea36, Wolfgang Lieb282, Thomas Lumley283 , Nicholas G Martin42, Winfried März55,284,285, Giuseppe Matullo89, Sarah E Medland42, Tony R Merriman28, Andres Metspalu106, Brian F Meyer286, Karen L Mohlke80, Grant W Montgomery42,287, Dennis Mook- Kanamori43,288, Patricia B Munroe92,289, Kari E North14, Dale R Nyholt42,290, Jeffery R O'connell61,62, Carole Ober49 40 , Albertine J Oldehinkel291, Walter Palmas292, Colin Palmer293, Gerard G Pasterkamp145, Etienne Patin197,198,199, Craig E Pennell294,295, Louis Perusse296,297, Patricia A Peyser98, Mario Pirastu298, Tinca JC Polderman50, David J Porteous44,45, Danielle Posthuma50,299, Bruce M Psaty300,301, John D Rioux266,302, Fernando Rivadeneira20,21,22, Charles Rotimi76, Jerome I Rotter16, Igor Rudan1 , Hester M Den Ruijter279, Dharambir K Sanghera75,303, Naveed Sattar192, Reinhold Schmidt46 45 , Matthias B Schulze58,59,304, Heribert Schunkert153,305, Robert A Scott12, Alan R Shuldiner61,62,306, Submitted Manuscript: Confidential 3 Xueling Sim29, Neil Small307, Jennifer A Smith98,265, Nona Sotoodehnia308, E-Shyong Tai29,121,309, Alexander Teumer126,310, Nicholas J Timpson93,311,312, Daniela Toniolo209, David-Alexandre Tregouet40, Tiinamaija Tuomi10,313,314,315, Peter Vollenweider316, Carol A Wang294,295, David R Weir265, John B Whitfield42, Cisca Wijmenga13, Tien-Yin Wong107,108, John Wright6 , Jingyun Yang245,246, Lei Yu245,246, Babette S Zemel268,317, Alan B Zonderman83, Markus Perola318 5 , Patrik KE Magnusson23, André G Uitterlinden20,21,22, Jaspal S Kooner19,39,254,319, Daniel I Chasman17,203, Ruth J F Loos15,320, Nora Franceschini14, Lude Franke13, Chris S Haley232,321, Caroline Hayward232, Robin G Walters11, John R B Perry12, Tōnu Esko106,322, Agnar Helgason5,128, Kari Stefansson5,79, Peter K Joshi1 , Michiaki Kubo179, James F Wilson1,232*. "Effects of autozygosity on a broad range of human phenotypes" Science.

10.Aida Jimenez-Corona Co-Authors: Robert G Nelson, Maria Jimenez-Corona, Sergio Hernandez- Jimenez, Paul Franks, Carlos Alberto Aguilar Salinas, Enrique Graue-Hernández, Mauricio Hernandez- Avila. Disparities in pre-diabetes and type 2 diabetes prevalence between indigenous and non-indigenous populations from Southeastern Mexico: The Comitan Study J Clin Translational Endocrinology

11.Vesta L. Richardson , Daniel López-Hernández, Aurora Bautista-Marquez, Sánchez-Díaz Iyari, Carlos Aguilar-Salinas, Laura Magaña Valladares. "Predictive factors for the approval and knowledge gain of a MOOC on type 2 diabetes mellitus in the primary health-care level" The Diabetes Educator.

13. Sergio Hernandez-Jimenez, Ana Cristina García-Ulloa, Omar Yaxmehen Bello-Chavolla, Carlos Alberto Aguilar Salinas, David Kershenobich Long-term effectiveness of a comprehensive care program. The CAIPaDi model. Diabetes Research and Clinical Practice

Book chapters: 67

Edited books: 18 1. Co-editor " Manual de Terapeutica Medica y Procedimientos de Urgencias" 1991. Edited by the Instituto Nacional de la Nutricion. 2.Aguilar Salinas CA, Hernandez Jimenez S, Hernandez Avila M, Hernandez Avila JE. Acciones para enfrentar a la diabetes. Documento de postura de la Academia Nacional de Medicina. Editorial Intersistemas. ISBN: 978-607-443-501-6

National or international grants: 14

Editorial committes 1. Co-editor Revista Mexicana de Nutrición y Endocrinologia 2005 2. Editorial comittee: Revista Mexicana de Nutrición y Endocrinología 2000-. 3. Editorial comittee: Revista de Investigación Clinica 1999- 4. Editorial comittee: Gaceta Médica de México 2005 5. Editorial comittee:“Recent patents on endocrine, metabolic & immune drug discovery”. 2005- 6. Editorial comittee: “Current Diabetes Reviews” 2004- 7. Editor Revista ALAD 2012- 8. Editorial comittee: Metabolism 2011- 9. Editorial comittee:Current Diabetes Reports 2012- 10. Editorial comittee:Current Obesity Reports 2012 - 11. Associated editor Atherosclerosis 2018 -

Signature______Date: September 5, 2019