The Capgras Delusion

Total Page:16

File Type:pdf, Size:1020Kb

The Capgras Delusion THE CAPGRAS DELUSION AN INTEGRATED APPROACH Neralie Diane Wise BA (Hon) Philosophy Macquarie University NSW Australia This thesis is presented for the degree of Doctor of Philosophy submitted in the Philosophy Department, Faculty of Arts Macquarie University August 2012 Table of Contents TABLE OF CONTENTS .....................................................................................................................II TABLE OF FIGURES ....................................................................................................................... VI ABSTRACT ....................................................................................................................................... VII STATEMENT OF CANDIDATE .................................................................................................. VIII ACKNOWLEDGEMENTS ............................................................................................................... IX INTRODUCTION ............................................................................................................................... 1 1. Introduction ................................................................................................................................................ 1 2. Thesis structure ......................................................................................................................................... 5 3. Part One ........................................................................................................................................................ 6 4. Part Two .................................................................................................................................................... 13 PART ONE ........................................................................................................................................ 20 CHAPTER 1: PHENOMENOLOGY AND DELUSIONS ........................................................... 21 1. Introduction ............................................................................................................................................. 21 SECTION ONE: KARL JASPERS.................................................................................................................... 21 1. Introduction ............................................................................................................................................. 21 2. Concepts ..................................................................................................................................................... 22 i) The psyche ............................................................................................................................................................................. 22 ii) Understanding.................................................................................................................................................................... 24 iii) Form and content ............................................................................................................................................................ 25 iv) The issue of reality .......................................................................................................................................................... 26 3. Delusions ................................................................................................................................................... 27 4. Conclusion ................................................................................................................................................. 30 SECTION TWO: FOLLOWING JASPERS ....................................................................................................... 31 1. Introduction ............................................................................................................................................. 31 2. Louis Sass .................................................................................................................................................. 32 i) Hyperreflexivity .................................................................................................................................................................. 33 ii) Body alienation .................................................................................................................................................................. 34 iii) Un-worlding ....................................................................................................................................................................... 34 iv) Subjectivization ................................................................................................................................................................ 35 3. Shaun Gallagher..................................................................................................................................... 37 i) Embodied and embedded cognition ......................................................................................................................... 38 ii) How the Body Shapes the Mind ................................................................................................................................. 39 iii) The multiple realities hypothesis ............................................................................................................................ 42 4. Conclusion ................................................................................................................................................. 45 CHAPTER 2: BRENDAN MAHER .............................................................................................. 47 1. Introduction ............................................................................................................................................. 47 SECTION ONE: BRENDAN MAHER ............................................................................................................ 47 1. Maher’s Challenge to Jaspers ........................................................................................................... 47 2. Maher’s Arguments............................................................................................................................... 49 i) The anomalous experience............................................................................................................................................ 49 ii) The question of rationality ........................................................................................................................................... 50 iii) Evolution and cognition ............................................................................................................................................... 51 iv) Impaired reasoning ........................................................................................................................................................ 52 3. Criticisms and Responses ................................................................................................................... 52 i) Why do most people fail to develop delusions when faced with anomalous experiences? ........... 52 ii) How does the model account for delusions that occur in the absence of any anomalous experience? ................................................................................................................................................................................ 53 iii) Why do patients develop a delusional explanation rather than a normal one? ............................... 54 iv) Why do patients, unlike normal people, fail to reject the explanation? ................................................ 54 4. Summary and Conclusion .................................................................................................................. 55 SECTION TWO: TESTING MAHER’S TWO CLAIMS .................................................................................. 55 ii 1. Introduction ............................................................................................................................................. 56 2. Biological Causes of Delusion .......................................................................................................... 56 i) Stroke, tumour, trauma, dementing illness and disease ................................................................................. 56 ii) Neuroimaging ..................................................................................................................................................................... 57 3. The Patient’s Thinking is Normal ................................................................................................... 58 i) Attributional style .............................................................................................................................................................. 59 ii) Conservation and observational adequacy .......................................................................................................... 60 iii) Probabilistic reasoning bias ....................................................................................................................................... 61 4. Summary and Conclusion .................................................................................................................
Recommended publications
  • Prevalence of Capgras Syndrome in Alzheimer's Patients
    Dement Neuropsychol 2019 December;13(4):463-468 Original Article http://dx.doi.org/10.1590/1980-57642018dn13-040014 Prevalence of Capgras syndrome in Alzheimer’s patients A systematic review and meta-analysis Gabriela Caparica Muniz Pereira1 , Gustavo Carvalho de Oliveira2 ABSTRACT. The association between Capgras syndrome and Alzheimer’s disease has been reported in several studies, but its prevalence varies considerably in the literature, making it difficult to measure and manage this condition. Objective: This study aims to estimate the prevalence of Capgras syndrome in patients with Alzheimer’s disease through a systematic review, and to review etiological and pathophysiological aspects related to the syndrome. Methods: A systematic review was conducted using the Medline, ISI, Cochrane, Scielo, Lilacs, and Embase databases. Two independent researchers carried out study selection, data extraction, and qualitative analysis by strictly following the same methodology. Disagreements were resolved by consensus. The meta-analysis was performed using the random effect model. Results: 40 studies were identified, 8 of which were included in the present review. Overall, a total of 1,977 patients with Alzheimer’s disease were analyzed, and the prevalence of Capgras syndrome in this group was 6% (CI: 95% I² 54% 4.0-8.0). Conclusion: The study found a significant prevalence of Capgras syndrome in patients with Alzheimer’s disease. These findings point to the need for more studies on the topic to improve the management of these patients. Key words: Capgras syndrome, Alzheimer’s disease, dementia, delusion, meta-analysis. PREVALÊNCIA DA SÍNDROME DE CAPGRAS EM PACIENTES COM DOENÇA DE ALZHEIMER: UMA REVISÃO SISTEMÁTICA E METANÁLISE RESUMO.
    [Show full text]
  • Paranoid – Suspicious; Argumentative; Paranoid; Continually on The
    Disorder Gathering 34, 36, 49 Answer Keys A N S W E R K E Y, Disorder Gathering 34 1. Avital Agoraphobia – 2. Ewelina Alcoholism – 3. Martyna Anorexia – 4. Clarissa Bipolar Personality Disorder –. 5. Lysette Bulimia – 6. Kev, Annabelle Co-Dependant Relationship – 7. Archer Cognitive Distortions / all-of-nothing thinking (Splitting) – 8. Josephine Cognitive Distortions / Mental Filter – 9. Mendel Cognitive Distortions / Disqualifying the Positive – 10. Melvira Cognitive Disorder / Labeling and Mislabeling – 11. Liat Cognitive Disorder / Personalization – 12. Noa Cognitive Disorder / Narcissistic Rage – 13. Regev Delusional Disorder – 14. Connor Dependant Relationship – 15. Moira Dissociative Amnesia / Psychogenic Amnesia – (*Jason Bourne character) 16. Eylam Dissociative Fugue / Psychogenic Fugue – 17. Amit Dissociative Identity Disorder / Multiple Personality Disorder – 18. Liam Echolalia – 19. Dax Factitous Disorder – 20. Lorna Neurotic Fear of the Future – 21. Ciaran Ganser Syndrome – 22. Jean-Pierre Korsakoff’s Syndrome – 23. Ivor Neurotic Paranoia – 24. Tucker Persecutory Delusions / Querulant Delusions – 25. Lewis Post-Traumatic Stress Disorder – 26. Abdul Proprioception – 27. Alisa Repressed Memories – 28. Kirk Schizophrenia – 29. Trevor Self-Victimization – 30. Jerome Shame-based Personality – 31. Aimee Stockholm Syndrome – 32. Delphine Taijin kyofusho (Japanese culture-specific syndrome) – 33. Lyndon Tourette’s Syndrome – 34. Adar Social phobias – A N S W E R K E Y, Disorder Gathering 36 Adjustment Disorder – BERKELEY Apotemnophilia
    [Show full text]
  • “Cat-Gras” Delusion: a Unique Misidentification Syndrome and a Novel Explanation
    Neurocase The Neural Basis of Cognition ISSN: 1355-4794 (Print) 1465-3656 (Online) Journal homepage: http://www.tandfonline.com/loi/nncs20 “Cat-gras” delusion: a unique misidentification syndrome and a novel explanation R. Ryan Darby & David Caplan To cite this article: R. Ryan Darby & David Caplan (2016) “Cat-gras” delusion: a unique misidentification syndrome and a novel explanation, Neurocase, 22:2, 251-256, DOI: 10.1080/13554794.2015.1136335 To link to this article: https://doi.org/10.1080/13554794.2015.1136335 Published online: 14 Jan 2016. Submit your article to this journal Article views: 1195 View related articles View Crossmark data Citing articles: 4 View citing articles Full Terms & Conditions of access and use can be found at http://www.tandfonline.com/action/journalInformation?journalCode=nncs20 Download by: [Vanderbilt University Library] Date: 06 December 2017, At: 06:39 NEUROCASE, 2016 VOL. 22, NO. 2, 251–256 http://dx.doi.org/10.1080/13554794.2015.1136335 “Cat-gras” delusion: a unique misidentification syndrome and a novel explanation R. Ryan Darbya,b,c and David Caplana,c aDepartment of Neurology, Massachusetts General Hospital, Boston, MA, USA; bDepartment of Neurology, Brigham and Women’s Hospital, Boston, MA, USA; cHarvard Medical School, Boston, MA, USA ABSRACT ARTICLE HISTORY Capgras syndrome is a distressing delusion found in a variety of neurological and psychiatric diseases Received 23 June 2015 where a patient believes that a family member, friend, or loved one has been replaced by an imposter. Accepted 20 December 2015 Patients recognize the physical resemblance of a familiar acquaintance but feel that the identity of that KEYWORDS person is no longer the same.
    [Show full text]
  • EASA Psychiatric Medication Guide Draft 5 12/8/17 1
    EASA Psychiatric Medication Guide Draft 5 12/8/17 Early Assessment & Support Alliance Center for Excellence (EASA4E) Medication Guide Authors: Suki K Conrad, M. Saul Farris, Daniel Nicoli, Richard Ly, Kali Hobson, Rachel Morenz, Elizabeth Schmick, Jessica Myers, Keenan Smart, Anushka Shenoy, and Craigan Usher Illustrator: Shane Nelson Introduction For many Early Assessment Support Alliance (EASA) participants, intervention with psychiatric medications is an essential component of recovery. EASA functions as a transdisciplinary team and thus we hope to familiarize all providers in the program with the following: the rationale for medication treatment decisions, general treatment targets, as well as the side-effect profiles for six commonly utilized medication classes (see table 1.) Table 1: Commonly utilized medication classes. Medication Class Description Also known as “neuroleptics,” this group can be broken down into first- generation antipsychotics (FGAs) and second-generation antipsychotics Antipsychotic (SGAs). These medications mainly work by blocking dopamine receptors— essentially “turning down the volume” on many psychotic symptoms. Includes serotonin reuptake inhibitors (SRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), atypical agents, and tricyclic antidepressants Antidepressant (TCAs). These medications mainly work by increasing neurotransmitter levels and changing the sensitivity of receptors to neurotransmitters, alleviating depression and reducing anxiety. Includes medications such as lithium and anticonvulsants
    [Show full text]
  • Brain Connectivity of Lesions Causing Delusional Misidentifications
    doi:10.1093/brain/aww288 BRAIN 2017: 140; 497–507 | 497 Finding the imposter: brain connectivity of lesions causing delusional misidentifications R. Ryan Darby,1,2,3,* Simon Laganiere,1,* Alvaro Pascual-Leone,1 Sashank Prasad4 and Michael D. Fox1,2,5 *These authors contributed equally to this work. See McKay and Furl (doi:10.1093/aww323) for a scientific commentary on this article. Focal brain injury can sometimes lead to bizarre symptoms, such as the delusion that a family member has been replaced by an imposter (Capgras syndrome). How a single brain lesion could cause such a complex disorder is unclear, leading many to speculate that concurrent delirium, psychiatric disease, dementia, or a second lesion is required. Here we instead propose that Capgras and other delusional misidentification syndromes arise from single lesions at unique locations within the human brain connectome. This hypothesis is motivated by evidence that symptoms emerge from sites functionally connected to a lesion location, not just the lesion location itself. First, 17 cases of lesion-induced delusional misidentifications were identified and lesion locations were mapped to a common brain atlas. Second, lesion network mapping was used to identify brain regions functionally connected to the lesion locations. Third, regions involved in familiarity perception and belief evaluation, two processes thought to be abnormal in delu- sional misidentifications, were identified using meta-analyses of previous functional magnetic resonance imaging studies. We found that all 17 lesion locations were functionally connected to the left retrosplenial cortex, the region most activated in functional magnetic resonance imaging studies of familiarity. Similarly, 16 of 17 lesion locations were functionally connected to the right frontal cortex, the region most activated in functional magnetic resonance imaging studies of expectation violation, a component of belief evaluation.
    [Show full text]
  • Capgras Syndrome Subbarayan Dhivagar1, Jasmine Farhana2
    REVIEW ARTICLE Capgras Syndrome Subbarayan Dhivagar1, Jasmine Farhana2 ABSTRACT Capgras syndrome is a neuropsychiatric disorder, and it is also known as impostor syndrome. People who experience this syndrome will have an irrational belief that someone they know or recognize has been replaced by an impostor. The Capgras syndrome can affect anyone, but it is more common in females and rare cases in children. There is no prescribed treatment plan for people who are affected with Capgras syndrome, but there is a supportive psychotherapeutic measure to overcome this delusional disorder. Keywords: Impostor delusion, Misidentification syndrome, Prosopagnosia. Pondicherry Journal of Nursing (2020): 10.5005/jp-journals-10084-12151 INTRODUCTION 1,2Department of Mental Health Nursing, Kasturba Gandhi Nursing Capgras syndrome is a type of delusional disorder in which a person College, Sri Balaji Vidyapeeth, Puducherry, India holds a delusion that a friend, parents, spouse, or other close Corresponding Author: Subbarayan Dhivagar , Department of relatives or pet animals has been replaced by an identical impostor. Mental Health Nursing, Kasturba Gandhi Nursing College, Sri Balaji It is otherwise called as Capgras delusion or impostor delusion. Vidyapeeth, Puducherry, India, Phone: +91 8754733698, e-mail: It may be seen along with other psychiatric disorders such as [email protected] schizophrenia, schizotypal, and neuro-related disorders. How to cite this article: Dhivagar S, Farhana J. Capgras Syndrome. Pon J Nurs 2020;13(2):46–48. HISTORICAL VIEW Source of support: Nil It is named after Jean Marie Joseph Capgras (1873–1950). He was a Conflict of interest: None French psychiatrist, who was best known for the Capgras delusion; it was described in 1923 in a study published by him.
    [Show full text]
  • Cotard's Syndrome
    MIND & BRAIN, THE JOURNAL OF PSYCHIATRY REVIEW ARTICLE Cotard’s Syndrome Hans Debruyne1,2,3, Michael Portzky1, Kathelijne Peremans1 and Kurt Audenaert1 Affiliations: 1Department of Psychiatry, University Hospital Ghent, Ghent, Belgium; 2PC Dr. Guislain, Psychiatric Hospital, Ghent, Belgium and 3Department of Psychiatry, Zorgsaam/RGC, Terneuzen, The Netherlands ABSTRACT Cotard’s syndrome is characterized by nihilistic delusions focused on the individual’s body including loss of body parts, being dead, or not existing at all. The syndrome as such is neither mentioned in DSM-IV-TR nor in ICD-10. There is growing unanimity that Cotard’s syndrome with its typical nihilistic delusions externalizes an underlying disorder. Despite the fact that Cotard’s syndrome is not a diagnostic entity in our current classification systems, recognition of the syndrome and a specific approach toward the patient is mandatory. This paper overviews the historical aspects, clinical characteristics, classification, epidemiology, and etiological issues and includes recent views on pathogenesis and neuroimaging. A short overview of treatment options will be discussed. Keywords: Cotard’s syndrome, nihilistic delusion, misidentification syndrome, review Correspondence: Hans Debruyne, P.C. Dr. Guislain Psychiatric Hospital Ghent, Fr. Ferrerlaan 88A, 9000 Ghent, Belgium. Tel: 32 9 216 3311; Fax: 32 9 2163312; e-mail: [email protected] INTRODUCTION: HISTORICAL ASPECTS AND of the syndrome. They described a nongeneralized de´lire de CLASSIFICATION negation, associated with paralysis, alcoholic psychosis, dementia, and the ‘‘real’’ Cotard’s syndrome, only found in Cotard’s syndrome is named after Jules Cotard (1840Á1889), anxious melancholia and chronic hypochondria.6 Later, in a French neurologist who described this condition for the 1968, Saavedra proposed a classification into three types: first time in 1880, in a case report of a 43-year-old woman.
    [Show full text]
  • On the Edge of Capgras' Syndrome
    JOURNAL OF PSYCHOPATHOLOGY Online First Case report 2021;Mar 20. doi: 10.36148/2284-0249-386 On the edge of Capgras’ syndrome Andrea Turano1, Cecilia Caravaggi2, Giuseppe Ducci2, Silvia Bernardini2, Pier Luca Bandinelli2 1 Department of Pyschiatry, Sapienza University of Rome, Sant’Andrea Hospital, Rome, Italy; 2 Department of Mental Health ASL Roma 1, Rome, Italy SUMMARY Capgras’ syndrome, the delusional belief in the existence of doubles of others or of one- self, belongs to the delusional misidentification syndromes (DMSs), a group of syndromes characterized by delusional misidentification of oneself and/or of other people. These syn- dromes are not codified as diagnoses per se on the DSM-5 or on the ICD-11, and are usually seen as specific presentations of broader psychiatric disorders. Capgras’ syndrome has been shown on both psychiatric and non-psychiatric disorders, thus not being a manageable tool in helping clinicians to define a diagnosis. Presenting what we believe is a special case of Capgras’ syndrome, we aim to propose a characterization of such syndrome very specific of schizophrenic – and thus psychiatric – conditions, which may turn especially useful in clinical pictures where no other psychiatric or medical symptoms are found and can help defining a diagnosis. Key words: Capgras’ syndrome, delusional misidentification syndromes, differential diagnosis Non c’è uomo che a forza di portare una maschera, non finisca per assimilare a questa anche il suo vero volto. Received: April 30, 2020 Accepted: December 10, 2020 (Nathaniel Hawthorne; La lettera scarlatta) Correspondence Pier Luca Bandinelli Introduction Department of Psychiatry, SPDC San Filippo In classic psychopathology there was a tendency toward giving names Neri, via G.
    [Show full text]
  • Delusional Misidentification Syndromes
    Jefferson Journal of Psychiatry Volume 10 Issue 1 Article 4 January 1992 Delusional Misidentification Syndromes Zeljko Jocic, M.D. University of North Dakota, Fargo, North Dakota Follow this and additional works at: https://jdc.jefferson.edu/jeffjpsychiatry Part of the Psychiatry Commons Let us know how access to this document benefits ouy Recommended Citation Jocic, M.D., Zeljko (1992) "Delusional Misidentification Syndromes," Jefferson Journal of Psychiatry: Vol. 10 : Iss. 1 , Article 4. DOI: https://doi.org/10.29046/JJP.010.1.001 Available at: https://jdc.jefferson.edu/jeffjpsychiatry/vol10/iss1/4 This Article is brought to you for free and open access by the Jefferson Digital Commons. The Jefferson Digital Commons is a service of Thomas Jefferson University's Center for Teaching and Learning (CTL). The Commons is a showcase for Jefferson books and journals, peer-reviewed scholarly publications, unique historical collections from the University archives, and teaching tools. The Jefferson Digital Commons allows researchers and interested readers anywhere in the world to learn about and keep up to date with Jefferson scholarship. This article has been accepted for inclusion in Jefferson Journal of Psychiatry by an authorized administrator of the Jefferson Digital Commons. For more information, please contact: [email protected]. Delusional Misidentification Syndromes Zeljko Jocic, M.D. Abstract Delusional misidentification syndromes are reviewed by their phenomenology, epidemiology, clinical characteristics, associated clinicalfindin gs, etiological theories, diagnostic evaluation, and treatment. Related neuropsychiatric syndromes are described and distinctions between them and delusional misidentification syndromes addressed. Current psychological and biologic-cognitive theories are briifly discussed. Thesepeculiarphenomena areprobably morefrequent than previously thought, ifthey are specifically sought and recognized.
    [Show full text]
  • Uncovering Capgras Delusion Using a Large-Scale Medical Records Database Vaughan Bell, Caryl Marshall, Zara Kanji, Sam Wilkinson, Peter Halligan and Quinton Deeley
    BJPsych Open (2017) 3, 179–185. doi: 10.1192/bjpo.bp.117.005041 Uncovering Capgras delusion using a large-scale medical records database Vaughan Bell, Caryl Marshall, Zara Kanji, Sam Wilkinson, Peter Halligan and Quinton Deeley Background Neuroimaging provided no evidence for predominantly right Capgras delusion is scientifically important but most commonly hemisphere damage. Individuals were ethnically diverse with a reported as single case studies. Studies analysing large clinical range of psychosis spectrum diagnoses. records databases focus on common disorders but none have investigated rare syndromes. Conclusions Capgras is more diverse than current models assume. Aims Identification of rare syndromes complements existing Identify cases of Capgras delusion and associated ‘big data’ approaches in psychiatry. psychopathology, demographics, cognitive function and neuropathology in light of existing models. Declaration of interests Method V.B. is supported by a Wellcome Trust Seed Award in Science Combined computational data extraction and qualitative (200589/Z/16/Z) and the UCLH NIHR Biomedical Research classification using 250 000 case records from South London and Centre. S.W. is supported by a Wellcome Trust Strategic Award ’ Maudsley Clinical Record Interactive Search (CRIS) database. (WT098455MA). Q.D. has received a grant from King s Health Partners. Results We identified 84 individuals and extracted diagnosis-matched Copyright and usage comparison groups. Capgras was not ‘monothematic’ in the © The Royal College of Psychiatrists 2017. This is an open majority of cases. Most cases involved misidentified family access article distributed under the terms of the Creative members or close partners but others were misidentified in Commons Non-Commercial, No Derivatives (CC BY-NC-ND) 25% of cases, contrary to dual-route face recognition models.
    [Show full text]
  • A Dictionary of Neurological Signs.Pdf
    A DICTIONARY OF NEUROLOGICAL SIGNS THIRD EDITION A DICTIONARY OF NEUROLOGICAL SIGNS THIRD EDITION A.J. LARNER MA, MD, MRCP (UK), DHMSA Consultant Neurologist Walton Centre for Neurology and Neurosurgery, Liverpool Honorary Lecturer in Neuroscience, University of Liverpool Society of Apothecaries’ Honorary Lecturer in the History of Medicine, University of Liverpool Liverpool, U.K. 123 Andrew J. Larner MA MD MRCP (UK) DHMSA Walton Centre for Neurology & Neurosurgery Lower Lane L9 7LJ Liverpool, UK ISBN 978-1-4419-7094-7 e-ISBN 978-1-4419-7095-4 DOI 10.1007/978-1-4419-7095-4 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2010937226 © Springer Science+Business Media, LLC 2001, 2006, 2011 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made.
    [Show full text]
  • Uncovering Capgras Delusion Using a Large-Scale Medical Records Database Vaughan Bell, Caryl Marshall, Zara Kanji, Sam Wilkinson, Peter Halligan and Quinton Deeley
    BJPsych Open (2017) 3, 179–185. doi: 10.1192/bjpo.bp.117.005041 Uncovering Capgras delusion using a large-scale medical records database Vaughan Bell, Caryl Marshall, Zara Kanji, Sam Wilkinson, Peter Halligan and Quinton Deeley Background Neuroimaging provided no evidence for predominantly right Capgras delusion is scientifically important but most commonly hemisphere damage. Individuals were ethnically diverse with a reported as single case studies. Studies analysing large clinical range of psychosis spectrum diagnoses. records databases focus on common disorders but none have investigated rare syndromes. Conclusions Capgras is more diverse than current models assume. Aims Identification of rare syndromes complements existing Identify cases of Capgras delusion and associated ‘big data’ approaches in psychiatry. psychopathology, demographics, cognitive function and neuropathology in light of existing models. Declaration of interests Method V.B. is supported by a Wellcome Trust Seed Award in Science Combined computational data extraction and qualitative (200589/Z/16/Z) and the UCLH NIHR Biomedical Research classification using 250 000 case records from South London and Centre. S.W. is supported by a Wellcome Trust Strategic Award ’ Maudsley Clinical Record Interactive Search (CRIS) database. (WT098455MA). Q.D. has received a grant from King s Health Partners. Results We identified 84 individuals and extracted diagnosis-matched Copyright and usage comparison groups. Capgras was not ‘monothematic’ in the © The Royal College of Psychiatrists 2017. This is an open majority of cases. Most cases involved misidentified family access article distributed under the terms of the Creative members or close partners but others were misidentified in Commons Non-Commercial, No Derivatives (CC BY-NC-ND) 25% of cases, contrary to dual-route face recognition models.
    [Show full text]