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Molecular changes during the development of Alzheimer's disease Wirz, K.T.S.

2013

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citation for published version (APA) Wirz, K. T. S. (2013). Molecular changes during the development of Alzheimer's disease.

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Download date: 30. Sep. 2021 Publications

Publications

Wirz KTS, Keitel S, Swaab DF, Verhaagen J, Bossers K. Early molecular changes in Alzheimer disease – can we catch the disease in its presymptomatic phase? Journal of Alzheimer's Disease. 2013, in press.

Wirz KT, Bossers K, Stargardt A, Kamphuis W, Swaab DF, Hol EM, Verhaagen J. Cortical beta amyloid protein triggers an immune response, but no synaptic changes in the APPswe/PS1dE9 Alzheimer’s disease mouse model. Neurobiology of Aging. 2013 May;34(5):1328-42.

Bossers K, Wirz KT, Meerhoff GF, Essing AH, van Dongen JW, Houba P, Kruse CG, Verhaagen J, Swaab DF. Concerted changes in transcripts in the prefrontal cortex precede neuropathology in Alzheimer’s disease. . 2010 Dec;133(Pt 12):3699-723.

Roet KCD, Wirz KTS, Franssen EHP, Verhaagen J. A role for neuropilins in the interaction between Schwann cells and meningeal cells. Chapter 6 in PhD thesis: Understanding the neural repair promoting properties of olfactory ensheathing cells – towards a treatment for spinal cord injuries, Free University , 2012.

Frey HP, Wirz K, Willenbockel V, Betz T, Schreiber C, Troscianko T, König P. Beyond correlation: do color features influence attention in rainforest? Frontiers in Human . 2011 Apr 8;5:36. van der Hel WS, Wirz KTS, Verlinde SAMW, van Rijen PC, van Veelen CWM, Varoqui H, Erickson JD, de Graan PNE. Expression of glial and neuronal neutral amino acid transporters in the hippocampus of patients with temporal lobe epilepsy. Chapter 3 in PhD thesis: Excitation in temporal lobe epilepsy: focus on the glutamate-­ glutamine cycle, University Utrecht. 2009.

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Curriculum vitae

Curriculum Vitae

Kerstin Tanja Simone Wirz was born on October 8, 1981 in Bonn-Bad Godesberg, Germany. She graduated from high school at the Gymnasium Burgdorf, Germany in 2001 after having spent one year as an exchange student at Novato High School, California, USA in 1999. After high school, Kerstin worked during a voluntary social year at a psychiatry for children and adolescents in Holzminden, Germany. She studied Cognitive Science in Osnabrück, Germany and La Laguna, Teneriffe, Spain from 2002 to 2005. A strong interest in neuroscience formed the basis for her internship at the cognitive neuroscience group of Prof. Stefan Treue at the German Primate Center in Göttingen where she performed psychophysical experiments on speed illusions. For her experimental bachelor thesis Kerstin worked on the influence of color features on attention at the department for neurobiopsychology of Prof. Peter König at the University of Osnabrück under supervision of Dr. Hans-Peter Frey. For her master studies, Kerstin moved to Tübingen, Germany in 2005 where she studied Neural and Behavioral Sciences. In 2006 she switched to the Neuroscience & Cognition master program at the University of Utrecht, the . During the first internship for this study she worked on the expression of glutamine transporters in temporal lobe epilepsy in the epilepsy research group of Dr. Pierre de Graan at the Rudolf Magnus Institute of Neuroscience at the University hospital in Utrecht under supervision of Dr. Saskia van der Hel. Kerstin performed her second internship at the Netherlands Institute for Neuroscience in Amsterdam in the group Prof. Joost Verhaagen under supervision of Dr. Kasper Roet, where she studied the role of neuropilin 1 and 2 in Schwann cells and spinal cord injury. In the same group, she was offered a PhD position in the TI Pharma project ‘Parkinson and Alzheimer disease: from dysregulated human brain targets towards novel therapeutics’ in 2008. Within this project, Kerstin worked on molecular changes during the development of Alzheimer’s disease under supervision of Prof. Joost Verhaagen, Dr. Koen Bossers and Prof. Dick Swaab.

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