Anti-IGF2BP3 Monoclonal Antibody, Clone 2G2-F21-E22

Anti-IGF2BP3 monoclonal antibody, clone 2G2- F21-E22 (DCABH-6276) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Mouse monoclonal to IMP3

Antigen Description RNA-binding protein that act as a regulator of mRNA translation and stability. Binds to the 5-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binds to sequences in the 3-UTR of CD44 mRNA.

Immunogen Recombinant fragment corresponding to Escherichia coli IMP3 (N terminal).

Isotype IgG1

Source/Host Mouse

Species Reactivity Escherichia coli

Clone 2G2-F21-E22

Purity Protein G purified

Conjugate Unconjugated

Applications WB

Positive Control MCF7, SKVO3, NTERA2, Jurkat, HeLa and K562 cell lysate

Format Liquid

Size 100 μg

Buffer pH: 7.4; Preservative: 0.02% Sodium azide; Constituents: 49% PBS, 50% Glycerol

Preservative 0.02% Sodium Azide

Storage Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

Ship Shipped at 4°C.

GENE INFORMATION

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Official Symbol IGF2BP3

Synonyms IGF2BP3; insulin-like growth factor 2 mRNA binding protein 3; insulin-like growth factor 2 mRNA- binding protein 3; cancer/testis antigen 98; CT98; IGF II mRNA binding protein 3; IMP 3; hKOC; VICKZ family member 3; IGF2 mRNA-binding protein 3; IGF-II mRNA-binding protein 3; KH domain containing protein overexpressed in cancer; KH domain-containing protein overexpressed in cancer; IMP3; KOC1; IMP-3; VICKZ3; DKFZp686F1078;

Entrez Gene ID 10643

Protein Refseq NP_006538

UniProt ID O00425

Chromosome Location 7p15.3

Pathway Binding of RNA by Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs), organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem;

Function RNA binding; mRNA 3-UTR binding; mRNA 5-UTR binding; nucleotide binding; protein binding; translation regulator activity;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]