Where No Healthcare Device Has Gone Before
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JUNE 2015 # 09 Upfront In Practice Next Gen Sitting Down With Discovery of the immune- Taking on the CAD Model predicts cancer Mamar Gelaye, Chief Executive brain missing link challenge in women survival and tumor sensitivity Officer of Omnyx, LLC 12 33 – 35 38 – 41 50 – 51 Where No Healthcare Device Has Gone Before Teams from around the world compete to make science fiction a diagnostic reality. 18 – 30 Visit our booth (no. 45) during the 27th European Congress of Pathology for a live demonstration SavaCentar, Belgrade, Serbia 5 - 9 September, 2015 Bringing routine microscopy to the next level For years, Sakura Finetek has been a key player within VisionTek ® optimizes live digital laboratories. Building on the success and principles of microscopy: SMART Automation, Sakura has broadened her horizons further, focusing on the pathologists themselves. Bringing live microscopy to the new digital world, Sakura Facilitates easy and accurate diagnosis Finetek proudly introduces: The VisionTek® live digital microscope, the first of its kind. Share live images Direct consultation The VisionTek® captures real-time images, for live viewing and precise measurements, all within seconds. The live User determines what and when to archive multi-view mode is perfect for complex cases, displaying multiple slides and stains on one screen, also offering the possibility to (z-stack) scan whole and partial slides. You decide what, when and how to scan. Sakura Finetek UK Ltd. visiontek.sakura.eu [email protected] Online this Month The Pathologist on Twitter What got you tweeting this Graph Lib @graphlib Infographic: High Value Healthcare month? Here are some of Needs Pathologists @Pathologists our most popular tweets @pathologistmag @DrMisialek and mentions… http://bit.ly/1MCo17q #Infographics The Pathologist @pathologistmag 9:15 PM - 8 Jun 2015 During which phase of #labtesting Bradford Pathology are the most errors made? Know Pathology @Know_Pathology @bradford_pathol Detailed infographic from Further to @pathologistmag @pathologistmag on the difference http://ow.ly/O0xC4 Digital First between a viral and bacterial report http://bit.ly/1cV3eJ6 infection #knowpathology: A … for role of pathology #bloodtest to quickly decide 10:59 AM - 9 Jun 2015 if an infection is #viral or #bacterial: http://bit.ly/1HWcVs1 #antibioticresistance 2:20 AM - 2 Jun 2015 The Pathologist @pathologistmag Defining #amyloid #pathology in The Pathologist @pathologistmag persons with and without #dementia Preanalytical accuracy in surgical syndromes - making the right pathology targeted by new diagnosis recommendations @Pathologists http://bit.ly/1IcvRmt http://ow.ly/O0yxA 8:45 AM - 4 Jun 2015 11:30 AM - 10 Jun 2015 Follow us @pathologistmag Contents 18 38 12 03 Online This Month Upfront Feature 10 From Kitchen to Clinic 18 Where No Healthcare Device Has Gone Before 07 Editorial 11 Viral Time Travel Eight teams from around the Autopsy on the Slab? world are competing for the By Fedra Pavlou 12 The (Immune–Brain) Qualcomm Tricorder XPRIZE, in Missing Link a prestigious, Star Trek-inspired race to create a portable and 12 A Liquid Revolution? consumer-friendly diagnostic 08 Contributors device which can monitor at least 14 (Not) All About the Base 16 distinct conditions. We ask some of the teams why they think 15 “Friendly” Bacteria Help they can win this exciting On The Cover Diagnose Disease competition, and XPRIZE Senior JUNE 2015 # 09 Director, Grant Campany tells Upfront In Practice Next Gen Sitting Down With Discovery of the immune- Taking on the CAD Model predicts cancer Mamar Gelaye, Chief Executive brain missing link challenge in women survival and tumor sensitivity Officer of Omnyx, LLC 12 33 – 35 38 – 41 50 – 51 Conceptualized by Star Trek, the Where No 16 Scoping Out the African Eye Worm us how this could really be a Healthcare Device Has Gone Before Teams from around the world compete to make science fiction a diagnostic reality. 18 – 30 first-ever medical tricorder may no diagnostic game-changer. longer be the stuff of science fiction. 17 High Hopes for Cancer Breathalyzer ISSUE 09 - JUNE 2015 Editor - Fedra Pavlou [email protected] Associate Editor - Roisin McGuigan [email protected] 33 Associate Editor - Michael Schubert [email protected] Senior Designer - Marc Bird [email protected] Junior Designer - Emily Strefford-Johnson [email protected] Chief Executive Officer - Andy Davies NextGen [email protected] Chief Operating Officer - Tracey Peers 38 Big Data, Hidden Knowledge [email protected] A mathematical tool is showing Publisher - Mark Goodrich promise in predicting ovarian [email protected] cancer patient survival, and Audience Insight Manager - Tracey Nicholls tumor sensitivity to platinum- [email protected] based chemotherapy. We ask Traffic and Audience Associate - Lindsey Vickers developer Orly Alter how this [email protected] model could impact oncology. Traffic and Audience Associate Jody- Fryett [email protected] 42 Color Power for Cancer Digital Content Manager - David Roberts Management [email protected] Yael Glickman explains how Mac Operator Web/Print - Peter Bartley a new staining method could offer a [email protected] noninvasive option for monitoring Tablet Producer - Abygail Bradley bladder cancer – and when paired [email protected] with digital pathology, a potential screening option. Apprentice, Social Media / Analytics - Stephen Mayers [email protected] Profession Published by Texere Publishing Limited, Booths Hall, 50 48 The Beauty of Pathology Booths Park, Chelford Road, Knutsford, Cheshire, WA16 8GS, UK What happens when pathologists get in touch with their inner artist? The European Society of General enquiries: Pathology runs artistic pathology www.texerepublishing.com In Practice exhibitions to find out, and they’d [email protected] love to get you involved… +44 (0) 1565 752883 33 The CAD Challenge [email protected] Diagnosing coronary artery disease in women isn’t easy, and Distribution: is more often overlooked than Sitting Down With The Pathologist is distributed worldwide through in men. An algorithm examining 10,000 printed copies to a targeted European age, sex and gene expression could 50 Mamar Gelaye mailing list of industry professionals and 22,500 electronic copies worldwide. provide a more sensitive Chief Executive Officer, Omnyx, ISSN 2055-8228 alternative to current tests. LLC Pittsburgh, Pennsylvania, USA. VISIT US AT Stand G005, IFCC 21st-25th June Stand 1018, AACC 26th-29th July NEW Flexible data management Bi-directional interface (LIS2-A2) Simple integration with LIS middleware Take control of your connectivity The new Hemo Control from EKF Diagnostics has the power to change the way you work. Now, as well as giving you best-in-class performance, accuracy and reliability, Hemo Control can easily connect to most hospital and lab systems. Find out how EKF can help you take control of your hemoglobin POCT. Visit us at ekfdiagnostics.com or call +49 (0)39 203 7850. Diagnostics for life ekfdiagnostics.com Autopsy on the Slab? Editorial Despite the intrinsic value of the ancient autopsy, it’s already extinct in some hospitals. Can it be saved? iven my Greek heritage, I decided to trace the historic derivation of the word autopsy; it comes from the Greek words ‘autos’ (self) and ‘opsis’ (see). Though Rokitansky (1804–1878) is known as the father of the modern autopsy, crude versions of the practice date backG to 3000 BC when people were quite skillfully performing human dissection (and mummification). Fast forward five millennia or so, and the autopsy still holds a great deal of value. It remains the only definitive way to confirm cause of death and sometimes diagnose disease – and it provides an abundance of knowledge to trainee pathologists as well as a window into hereditary conditions for family members. Nevertheless, the rate of hospital autopsy is in a dire state of decline. Why? A well-cited catalyst is the fact that in 1971 the US Joint Commission on Accreditation of Healthcare ( JCAHO) agreed to eliminate minimum autopsy requirements from the regulations for hospital accreditation (1, 2). The continuous decline ever since has raised alarm bells within the pathology community: “For better or worse, the practice is on the verge of extinction,” warned authors of a recent report from the UK (3), which found that autopsies were only performed in just over 0.5 percent of all UK hospital deaths. In fact, the procedure has been completely eradicated in nearly one in four UK National Healthcare Service trusts. The authors urge that immediate action be taken before autopsies completely disappear. References In fairness, the impact of their absence is not yet fully known, but 1. G. G. Fillenbaum et al., “The Consortium Europe doesn’t appear keen to tempt fate. In March 2015, the to Establish a Registry for Alzheimer's European Critical Care Foundation announced its plan to raise Disease (Cerad), Part XIII: Obtaining the issue of autopsy decline with European institutions, and to Autopsy in Alzheimer's Disease”, Neurology, work with partners and key stakeholders to “reverse this trend for the 46, 142–145 (1996). ultimate benefit of patients and healthcare systems.” (4) 2. S. J. McPhee, “Maximizing the Benefits of So, can the autopsy be saved