A Genetic Chronology of African Y-Chromosomes R
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Indian Journal of Fundamental and Applied Life Sciences ISSN: 2231– 6345 (Online) An Open Access, Online International Journal Available at http://www.cibtech.org/jls.htm 2017 Vol. 7 (2) April-June, pp. 24-37/Winters Research Article A GENETIC CHRONOLOGY OF AFRICAN Y-CHROMOSOMES R-V88 AND R-M269 IN AFRICA AND EURASIA *Clyde Winters Department of Archaeogenetics, Uthman dan Fodio Institute, Chicago, Illinois 60643 *Author for Correspondence ABSTRACT There is a global distribution of Y-Chromosome R-M343 subclades across the African continent. The major subclades are R-M269 and R-V88. The V88 subclade is the oldest clade to separate from R-M343. The V88 sub-clade, had relatives in Early Neolithic samples from across a wide geographic area from Iberia, eastward to Germany and Samara. This would place carriers of relatives of V88 among the Yamnaya and Bell Beaker people. Given the wide distribution of V88 and M269 in Africa and Neolithic Europe suggest that, the Bell Beaker and Yamnaya people were Africans, not Indo-Europeans, because these cultural complexes and the people who practiced these cultures originated in Africa. Keywords: Haplogroup (hg), Bell Beaker, Iberia, Yamnaya, Subclades, Megalithic INTRODUCTION The Bell Beaker culture spread from Iberia to the rest of Europe (Haak et al., 2015). The eastern Corded Ware and even earlier Yamnaya ceramic decorations are characteristic of the African “Maritime Beaker complex” that was carried from Morocco to Iberia (Turek, 2012; Winters, 2017). Because the Bell Beaker cultural complex was also present in North Africa, makes it clear Africans took R-V88 and R-M269 to Iberia and across Europe. Most researchers assume that Y-Chromosome R*-M173 originated in the Levant or Southern Europe among non-African populations. This theory lacks archaeological support. Neolithic migrants into Europe from the Levant and Iberia were Sub-Saharan Africans (SSA) (Brace et al., 2006; Boule and Vallois, 1957; Domínguez, 2005; Winters, 2010, 2010b, 2011, 2011b). Holliday (2000), tested the hypothesis that if modern Africans had dispersed into the Levant from Africa, "tropically adapted hominids" would be represented in the archaeological history of the Levant, especially in relation to the Qafzeh-Skhul hominids. This researcher found that the Qafzeh-Skhul hominids (20,000- 10,000 BP), were assigned to the Sub-Saharan population, along with the Natufian samples (4000 BP). Holliday (2000) also found African fauna in the area. If they were Sub-Saharan Africans in the Levant the Neolithic Europeans were also SSA. It was between 4.2kya that the Agro-Pastoral people migrated into the Steppe and began to migrate Westward into Western Europe. There were many Africans in Neolithic Iberia (Dominguez, 2005). African haplogroups have been found at Tres Montes Bronze Age Navarra, they were found in many ancient Iberian skeletons. Tres Montes Navarra was a center of Bell Beaker culture. As late as 2130 BCE we find haplogroup L2 in Iberia (Dominguez, 2005). In addition, as early 10kya we find carriers of M1 in Andalusia (Hernández et al., 2015). Haplogroup M1, is recognized as an African clade (Winters, 2016). In Iberia, seventy percent of the mtDNA in Tres Montes Navarra was of Sub-Saharan African origin (Dominguez, 2005). The African haplogroups belonged to the L, L2 and L3 clades. Haplogroups L2 and L1b, are concentrated in western-central Africa, particularly along the coastal areas. Dominguez (2005), noted that much of the ancient mtDNA found in Iberia has no relationship to the people presently living in Iberia. Dominguez (2005) found that the lineages recovered from ancient Iberian skeletons are the African lineages L1b, L2 and L3. Almost 50% of the lineages from the Abauntz Chalcolithic deposits and Tres Montes, in Navarre are the Sub-Saharan lineages L1b, L2 and L3 dating back to 2130 BCE. The appearance of phylogenetically related sequences of hg L3 present in many ancient Iberian skeletons suggest that this haplogroup may have a long history in Iberia. This would support the presence of West Africans in Iberia during the Neolithic period. Centre for Info Bio Technology (CIBTech) 24 Indian Journal of Fundamental and Applied Life Sciences ISSN: 2231– 6345 (Online) An Open Access, Online International Journal Available at http://www.cibtech.org/jls.htm 2017 Vol. 7 (2) April-June, pp. 24-37/Winters Research Article MATERIALS AND METHODS Method The research design used in this study is a literature based research methodology. We analyzed the DNA literature relating to the subclades of Y-Chromosome R-M343 found among Africans and Eurasians. The sample includes genomic data from Haak et al., (2015), Olalde et al., (2017), Kivisild (2017), Mathieson et al., (2017), Wood et al., (2005), Curciani et al., (2010), and Berniell-Lee et al., (2009). The frequencies of the R1 clades found among Africans and Eurasians in Table 1 and Table 2, are taken from these sources. An inter-population comparison of African and Eurasian genomes from the R1 clade was conducted to make a database of shared Y-Chromosome R haplogroups and clade frequencies. Data mining of the literature was used to determine haplogroup frequencies presented in this study. RESULTS AND DISCUSSION Results Haplogroup R1 in Africa R1 originated in Africa and spread into Eurasia (Winters 2010, 2011, 2016). The R-V88 subclade has its highest frequency in West Africa. This view is supported by the presence of V88 in Europe as early as 18kya, and carriers of this clade were among the Beaker pottery tradition (Kivisild, 2017). The Beaker pottery tradition expanded from Africa, to Iberia and thence the rest of Europe. Y-chromosome R1 is found throughout Africa. The pristine form of R1*-M173 is only found in Africa (Coia et al., 2005; Cruciani et al., 2002; Cruciani et al., 2010; Winters, 2010, 2011). The age of Y- Chromosome R is 27ky (Kivisild, 2017). There is a great diversity of the macrohaplogroup R in Africa as illustrated in Figure 1 and Table 1. Y-Chromosome R is characterized by M207. The V45 Mutation was recognized as M207 in 2010 (Winters, 2011) (Figure 1). Haplogroup V88 has the greatest frequency in Africa. It is predominately carried by Chadic speakers, and ranges between 2-60% among Central African Niger-Congo speakers (Cruciani et al., 2010). Researchers have found that the TMRCA of V88 was 18 kya (Kivisild, 2017). Haplogroup V88 is found among African populations. ISOGG 2010 Y-DNA haplogroup tree made it clear that V45 was phylogenetically equivalent to M207 (Cruciani et al., 2010; Winters, 2011). The most common R haplogroup in Africa is R1 (M173). The names for African R Y-Chromosome haplogroups in Africa are constantly being changed. In Figure 1, we see that in 2010, a predominant R Y-Chromosome clade in Africa is haplogroup R1b (Cruciani et al., 2002; Cruciani et al., 2010; Berniell-Lee et al., 2009; Winters, 2016; Wood et al., 2005) and R1b1 (Berniell-Lee et al., 2009) . Cruciani et al., (2010) discovered new R1b mutations including V7, V8, V45, V69, and V88. Geography appears to play an insignificant role in the distribution of haplogroup R in Africa. Cruciani et al., (2010) has renamed the R*-M173 (R P-25) in most of Africa V88. The TMRCA of V88 was 18 kya (Kivisild, 2017). Figure 1: African Y-Chromosomes 2010 Centre for Info Bio Technology (CIBTech) 25 Indian Journal of Fundamental and Applied Life Sciences ISSN: 2231– 6345 (Online) An Open Access, Online International Journal Available at http://www.cibtech.org/jls.htm 2017 Vol. 7 (2) April-June, pp. 24-37/Winters Research Article Y-chromosome V88 (R1b1a) has its highest frequency among Chadic speakers, while the carriers of V88 among Niger-Congo speakers (predominately Bantu people) range between 2-66%. Haplogroup V88 includes the mutations M18, V35 and V7. Cruciani et al., (2010) revealed that R-V88 is also carried by Eurasians including the distinctive mutations M18, V35 and V7. Haplogroup R1b1-P25 was originally thought to be found only in Western Eurasia. Haplogroup R1b1* is found in Africa at various frequencies. Today R1b1 is called R-L278. The first offshoot of R1b-M343 was V88. The Y-Chromosome V88 is a signature African haplogroup. Kivisild (2017) noted: "Interestingly, the earliest offshoot of extant haplogroup R1b-M343 variation, the V88 sub-clade, which is currently most common in Fulani speaking populations in Africa (Cruciani et al., 2010) has distant relatives in Early Neolithic samples from across wide geographic area from Iberia, Germany to Samara." The relative of V88 in ancient Europe was R1b1. This makes it clear that the V88 sub-clade, had relatives in Early Neolithic samples from across a wide geographic area from Iberia, Germany to Samara (Haak et al., 2015; Kivisild, 2017). This would place carriers of V88 among the Yamnaya and Bell Beaker people. Given the wide distribution of M269 in Africa, the carriers of this haplogroup in Neolithic Europe were probably also Africans since the Bell Beaker people/culture originated in Morocco as noted by Turek (2012). Many researchers have commented on the large number of R-V88 carriers who speak Afro-Asiatic languages. But few researchers have noticed that many Niger-Congo speakers and Khoisan carry R-M269 (R1b1b2). Interestingly, R-M269 is spread from North Africa, to Guinea-Bissau in West Africa, down to Numibia and South Africa in Southern Africa. Many Sub Saharan Africans carry R1b1b2. In Namibia around 8% of the population carry R1-M269. Wood et al., (2009) found that Khoisan (2.2%) and Niger-Congo (0.4%) speakers carried the R-M269 y- chromosome. The frequency of R-M269 among Guinea-Bissau populations was 12% (Carvalho et al., 2010). Gonzalez et al., (2012), found that 53% of the subjects carrying the R1 Y-Chromosome in his study carried subclade R-M269.