CAPNS1 Antibody Cat. No.: 22-296
CAPNS1 Antibody
Immunohistochemistry of paraffin-embedded human liver Immunohistochemistry of paraffin-embedded human colon using CAPNS1 antibody cancer using CAPNS1 antibody (22-296) at dilution of 1:100 (40x lens). (22-296) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human esophageal cancer using CAPNS1 antibody (22-296) at dilution of 1:100 (40x lens).
Specifications
September 30, 2021 1 https://www.prosci-inc.com/capns1-antibody-22-296.html HOST SPECIES: Rabbit
SPECIES REACTIVITY: Human, Mouse, Rat
Recombinant fusion protein containing a sequence corresponding to amino acids 69-268 IMMUNOGEN: of human CAPNS1 (NP_001740.1).
TESTED APPLICATIONS: IF, IHC, WB
WB: ,1:500 - 1:2000
APPLICATIONS: IHC: ,1:50 - 1:100
IF: ,1:50 - 1:100
POSITIVE CONTROL: 1) BT-474
2) U-251MG
3) SKOV3
4) Mouse lung
5) Mouse heart
6) Mouse spleen
PREDICTED MOLECULAR Observed: 28kDa WEIGHT:
Properties
PURIFICATION: Affinity purification
CLONALITY: Polyclonal
ISOTYPE: IgG
CONJUGATE: Unconjugated
PHYSICAL STATE: Liquid
BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.
Additional Info
OFFICIAL SYMBOL: CAPNS1
CALPAIN4, CANP, CANPS, CAPN4, CDPS, CSS1, calpain small subunit 1, CANP small subunit, calcium-activated neutral proteinase small subunit, calcium-dependent protease ALTERNATE NAMES: small subunit 1, calcium-dependent protease, small subunit, calpain 4, small subunit (30K), calpain regulatory subunit, calpain, small polypeptide, epididymis secretory sperm binding protein
GENE ID: 826
September 30, 2021 2 https://www.prosci-inc.com/capns1-antibody-22-296.html USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background and References
This gene is a member of the calpain small subunit family. Calpains are calcium- dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of BACKGROUND: both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants.
ANTIBODIES FOR RESEARCH USE ONLY.
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September 30, 2021 3 https://www.prosci-inc.com/capns1-antibody-22-296.html