Department of Pediatrics
2010 Annual Academic Review
UT Southwestern Medical Center Children’s Medical Center Dallas
2010 Annual Academic Review
Contents
Introduction and Chair Activities 3 Collaborative Partnerships 11 Education 13 Allergy & Immunology 25 Cardiology 33 Critical Care Medicine 43 Emergency Medicine 57 Endocrinology 67 Gastroenterology 75 General Pediatrics 85 Genetics & Metabolism 97 Hematology-Oncology 101 Hospitalist Medicine 119 Infectious Disease 127 Neonatal Perinatal Medicine 135 Nephrology 149 Neurology 155 Pulmonary & Vascular Biology 165 Respiratory Medicine 173 Rheumatology 181 Grants 187 Publications 201
UT Southwestern Medical Center Department of Pediatrics 5323 Harry Hines Boulevard Dallas, Texas 75390-9063 214-648-3383
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Affiliatedwith is the only academicUT pediatric Children’s Southwestern, medical in and center North is dedicated Texas, exclusively care children of from birth theto comprehensive 18. age to is recognized the among bestChildren’s pediatric hospitals in the country by 10 of the subspecialties covered in the survey, including Top the of subspecialties in the10 including covered survey, Top rankings10 in Orthopedics, Urologyand Nephrology. In and Center a Magnet is a Level I Trauma Children’s addition, Children’s nursing excellence. Recognition for hospital
Parkland System Health & Hospital Children for Scottish Hospital Rite Texas Children’s Medical Center Dallas Medical Center Children’s Collaborative PartnershipFacilities Premier with Collaborative provides care than inprovides more 50 pediatric intestine, heart subspecialties, pediatric liver, and and bone kidney, is a major significant committo hospital continues The to marrow transplantresources expanding center. services,including on mainthe floors the new addition of campus Dallas;in a second full-serviceTexas; an medical Plano, in center care andoutpatient surgery in Southlake, center and the pediatric of establishment a network of primary Texas; care locatedoffices Metroplex. the throughout the highest standard of care for patients. for care of the highest standard Ranked among the academic top medical in the centers UT faculty among its Southwestern includes world, four PrizeNobel winners, and 40 elected researchers physicians their of national specialtyas presidents associations, and medical thethree-fourths of National members Texas’ of the – prestigious Sciences scientific society most of Academy in the America. of largest is one academic physician It practices in the serving Southwest, referral as center a major diseases with patients for complex and providing care for total visitsnearly inpatient 97,000 and 1.7 approximately millionvisits research breakthroughs institution annually. pioneering outpatient A premier in cardiovascular disease, health, UT Southwestern offers an unsurpassed and neurosciences women’s cancer, pediatricheart diseaseprogram thatin achieved the association with first successful Children’s pediatricheart transplant Dallasin 1988. in Center UT Southwestern Medical UT Southwestern In conjunction with UT Southwestern, there is access to st is access to there UT Southwestern, with conjunction In The Department of Pediatrics at UT Southwestern Medical Center offers enhanced opportunities through its close its through opportunities enhanced offers Medical Center UT at Southwestern Pediatrics of The Department institutions: teaching premier three with association Collaborative Partnerships 12 dramatically impact the lives of children worldwide. of lives children the impact dramatically scoliosis, idiopathic with associated gene first the of TSRHC’sthrough discoverytheincluding research efforts, developed technologies new and breakthroughs medical The 2010. fiscal 2,146 in and performed outpatient surgeries visits more than 200,000 patients since its inception, with 39,625 to age 18, treated has hospital Texas the birth from children Serving disordersas dyslexia. such and learning bifida, spina as such disorders neurological related certain conditions, centers for of treatment pediatric orthopedic the leading isone Hospital forTexas nation’s of Rite Children the Scottish Children Texas Rite Hospitalfor Scottish most diverse one compositions and treat largest of vans area. the of four the patients mobileand in healthcare women’s centers, centers, nine 11 hospital, 11 health wealthy, main family youth and community Parkland’s clinics From homeless poor and the to the at Parkland. Texaspercent North training doctors in of formal have the obtained equipment tools and 50 state-of-the-art More neonatesand for and annually. severely than 1,200 premature infants is regarded as among the best. A Level 90-bed III Neonatal Care Unit provides the most health professionals skilled for families. patients and tranquility and of environment healing provide an Located at 7601 knowledge. of and base talent Southwestern, avast providing from UT at Children’s includes specialists at Legacy Preston Road staff medical the Children’s Like Dallas, medicine. in fetal in Plano, Texas, cardiology, maternal ENT, and including medicine sports the campus services, subspecialty array pediatric of full offersa Legacy sits on a 155-acre outpatient center. alarge and care Children’sservices at site with pharmacy and diagnostic a 24-7 “green emergency department, space” rooms, operating four state-of-the-art beds, intensive care six preserved to Plano, Texas,hospital, located in includes 72 inpatient beds, full-service beyond. and The of Dallas north of families number of Children’s growing Center to the Medical service world-class the extends Children’s Center at Legacy Medical Legacy Children’s Center at Medical System Parkland Health &Hospital is the second largest civilian center in the United center the in States and second civilian is the largest Center Burn The Parkland women and infants. and trauma, epilepsy, cord injuries, spinal gastroenterology, orthopedics, endocrinology, cancer, cardiology, burns, in Excellence TodayCenters at offers hospital treated Parkland. of the County Dallas in 62 percent cases region of with trauma Level I the Center in Trauma certified first includes the &WorldNews Report “America’s Hospitals” for Best 16 by consecutive years one &Hospital named System of was Health Parkland . Parkland’s legacy of achievements achievements of legacy Parkland’s . U.S. U.S. Education 13 Associate Professor Associate Jeffrey McKinney, M.D., Ph.D. M.D., McKinney, Jeffrey Director, Pediatric Resident Education Pediatric Director, Professor of Pediatrics, Obstetrics/Gynecology, and Assistant Professor of Pediatrics at UT Southwestern UT Southwestern at Pediatrics of Professor Assistant Education is Associate Professor of Pediatrics and the and Pediatrics of Professor is Associate Medical andhis Center the at Director residency of Pediatric completed Clerkship, Medical in Center UT 2004 Southwestern/Children’s and then pursued subspecialty training in pediatric endocrinology through UT at a fellowship Southwestern. Since his of trainingthe completion Adhikari Dr. has his split time between his clinical responsibilities, providing children care all for of ages with disorders, hormonal his research interests, primarily focused beta on cell preservation in type 1 diabetes, and Adhikari Dr. ashis Clerkship Director. role degree earned Science at of his Bachelor the University of Florida in Gainesville in 1996 and received his medical degree from Miamithe of University Medicine of in School 2001. Professorship in Pediatrics. His research focus is on mechanisms modulating modulating mechanisms on is focus research His Pediatrics. in Anesthesiology in the Division of Neonatal-Perinatal Medicine at UT Southwestern, serves as the the Education and L. Fellowship Director George holds of MacGregor Professorship of renin-angiotensin andthe umbilicaluteroplacental development flows, blood system, cardiovascular estrogens in of pregnancy role and fetal-neonatal blood obtained Rosenfeld regulation. hispressure medical Dr. degree from Emory University, Atlanta, Georgia, training in Post-doctoral 1966. at Pediatric Residencies included and Bronx Connecticut, Haven, - 1967, New 1966 Medical Haven Center, Yale-New Municipal and New Albert Center Hospital Einstein College Medicine, York, New a Pediatric Pulmonary - 1970, Albert 1967 at Medicine Fellowship Einstein York, and a Research inFellowship Neonatal-Perinatal - 1971 Medicine,College of 1970 He - 1973. 1971 Denver, Medicine Medical the Colorado at of University Center, has thejoined had continuous Rosenfeld UT Southwestern faculty Dr. in July 1973. NIH funding than peer-reviewed more than 30 years for and more has published 170 manuscripts. Charles R. M.D., Rosenfeld, Charles Soumya Adhikari, M.D., Adhikari, Soumya Professor Education Education Assistant Professor Director, Pediatric Clerkship Pediatric Director, Director, Pediatric Fellowship Pediatric Director, Soumya Adhikari, M.D. Soumya Charles R. Rosenfeld, M.D. Charles R. Rosenfeld, Jeffrey McKinney, M.D., Ph.D., M.D., McKinney, Jeffrey One of the the of threeOne of missions Department major Pediatrics of medical is theof education students, residents, postdoctoral and other fellows health transmitting care by professionals knowledge, instilling learning, for excitement the for goals educational specific has division Each process. during raised the questions translating refining and and for divisions fellows prepare Most students to programs and also education fellowship residents. which provide have an academic career. Residency Program Director. He has a B.S.E. in Biomedical Engineering from the from Engineering in Biomedical has a B.S.E. He Director. Residency Program in Physiology degree a also received He Engineering. of College Iowa of University from degrees Ph.D. and M.D. by followed as a Rhodes Scholar, University Oxford at geographic and patient seek additional To Medicine. of College Iowa of the University he where Hospital, Children’s Haven New Yale at officer he was a house diversity, Between 1998 Yale. at member faculty junior and disease infectious fellow as an stayed Pediatric for service awards top teaching or Yale’s of all three 2003 he received and Diseases the Infectious to was recruited He the Year. of Attending and Fellow Resident, he was elected Pediatric in 2003, where Louis in St. University Washington at faculty McKinney in 2009. Dr. medical students in 2008 and residents by the Year of Teacher program of since 2009 in his role Center Medical has been UT Southwestern with in Education. Professorship Bass, Jr. the Harry W. holds He director. Education 14 Gastroenterology, Endocrinology and others are available for fourth-year students as well. In addition, in the past past the in addition, In well. as for students available fourth-year are others and Gastroenterology, Endocrinology Hematology-Oncology, Pediatric including clinics Nephrology, subspecialty various of any the in experiences Extended Medicine. Emergency Intensive Unit Pediatric Care and Intensive IntensiveNeonatal Unit, Unit, Pediatric Cardiovascular the Care Care rotations the in acute/intensive via in experiences themselves care immerse Students can at Children’s Parkland. and advance in children of for another caring in career foundation their path, the strengthen to department just or pediatrics offers in career numerous eventual an for preparation opportunities to fourth-year students through the facilitiesindividual learningFourth-year goals. Whether medical students students want Pediatrics. in subject exam Examiners ofNational Board Medical at to UT gain Southwestern a more points average above scored Southwestern national students in-depth for the UT three on clerkships the comparable pediatric have exposure more For assessments. 2009-2010core the continue clerkship to averages outpace year, national on academic standardized flexibility to pediatric the through rotating Students resources. educational their to for one students all subspecialties created place the to give towas turn tailor their year, Newly aweb this student clerkship site themselves. to students the agenciesdedicated and academic regulatory national in schedule school faculty,an from based is ongoingon on reviewed basis feedback medical curriculum The entire Pediatrics. to meet of Department the in divisions the all nearly in by faculty facilitated discussions case-based sessions interactive and Pediatrics (COMSEP) Student Education in core on on Medical the based competencies published Council by as the curriculum A full is taught through bedside clinical supervision, daily rounds, in addition to various didactic environment. teaching academic provision into the outside of perspective care ofa unique atraditional latter students weekThis community. provides Dallas the in spend aweek office atprivateof a the pediatrician general to aforementioned the and opportunity Student Clinic, Medical the in focused experience of ambulatory weeks two Parkland, in nursery newborn the at care neonatal to exposure one-week a trainees provides experience outpatient The on wards. weeks one two hospital’s of and ward the subspecialty on pediatrics ageneral time of weeks their two spend students patientof care: aspects all in student participation maximize to aligned inpatient is The experience settings. ambulatory at Children’s various in units four weeks another and inpatientspend on four service the weeks eight-weekthis students rotation, During offices. their in students medical by education hosting student in participate the around from area Northwho volunteerTexas to pediatricians offices of select community uniquely, the through housed Southwestern. UT at students atmedical units eight-weekan consistscare the of many through rotationcurriculum third-year Children’s element required the This medical of for Pediatrics in clerkship core the is offerings these of center the At Medical Center, programs. many in their through care medical breadth of pediatric addition full theto explore the opportunity to offerstudents strives department education, the well-rounded and medical to select components one as central of the of long a has beenrecognized illness and health locationsA solid foundation childhood in of theone corethemissions Pediatrics. Department of students remains Thethese education of annually. of students at Parkland University the of schools one Texas in As ofapproximately Southwestern accepts four medical UT 230-240 system, Health & Hospital System Education Student Medical and, physicians. physicians. to the full exposure to hospital gain the located throughout clinics breadth care subspecialty of many the rotate through also students of specialized weeks, two these During 3rd training. of year their aspects care other many in than level of ahigher responsibility students provided physician provides attending their and be seenby them by staff only patients who present that to MSCwill Knowing who volunteer time. their pediatricians local with and of faculty the the from physicians attending with directly work Department (MSC), students Student Clinic third-year Medical the In of Pediatrics at UT Southwestern Education 15 The departmentThe takespride in great quality the Excellence of teachingby At provided entire faculty. the 2010 the faculty four in members the departmentin teaching Annual Education received ceremony, and Reception Award facultyone Preclinical recognized awards. for These member in role theirincluded MS1 excellence the for curriculum and Mihalic), (James two (Angela Pediatrics Amatruda), an Clerkship Preclinical Core MS2 Teaching Award Teaching (ChristinaAwards Bourland most telling, Perhaps and Paul Harker-Murray). 26 students from the graduating medical pursue a career to chosen program in pediatrics have combined including pediatrics. some or class 2010 school of Faculty from the Department Pediatrics of also participate, often in leadership roles, in the more didactic curriculum theof first yearsmedical of two including such school, key courses asbiochemistry genetics, and medical ethics. Beginning with faculty academic the year, 2007-2008 inmembers the department also in served the as mentors a mentored Each UT Southwestern. at system colleges new six of medicalgroup students in both second-year first- and classes and delivered curricula such as professionalism and ethics, communication skills like taking patients’ histories, diagnostic and physical exam skills, and clinical reasoning and interpretation skills through weekly small participate to students of group first The meetings. group in the colleges program will graduate this year. Medical students their rated experience their on as Pediatrics overwhelmingly Clerkship in 2009-2010 positive. from course evaluations feedback Student has specifically remained positive, consistently autonomy, to relates it as clinical of UT of promotion skills, graduation questionnaire, 91.5% On the internship. 2010 and for preparation Southwestern students rated their educational experience continuing as “good” a trend excellence of “excellent,” or in that the measure past for 5 years. year, a total of 39 students from outside institutions students a total came from Medical outside 39 of UT to to year, Center and Southwestern Children’s visitingdo in rotations Pediatrics. department The also offers,continues to and tostrive increase of, the number international-health elective opportunities students. for Education 16 the program and the education of the residents. its and program the strengthen that insights talents and Coordinator, unique and complimentary Bayé,Program Dawn offer They MBA. Dorothy Sendelbach, Directors, Gore, M.D. M.D., Lauren program’s the and the and Program Associate two with is led by The M.D.,McKinney, Jeffrey program Director, Ph.D., Program who and collaboratively closely works Pediatric ProgramTeam Residency resident resident meet to feedback discuss divisions provided of rotations. evaluation through All divisions. by all of experiences educational review scores, in-depth ACGME other hours duty and an and complianceexamination issues, scores, certifying residents. Evaluations include examination resident assessment of rotations faculty, in-training and chief future and current and areas, ambulatory inpatient and the leaders within educational mentors, leaders, program includecadreevaluators of our by These longitudinal yearly stakeholders. multiple twice evaluated is The program training. follow throughout up occurs longitudinal and of care continuity with pediatrics in subspecialty training Additional teams. service ward subspeciality and newborn units, intensive care nursery, pediatric and neonatal teams, medicine ward pediatric room, emergency the in practiced as medicine pediatric consult in education core services 13 four-week year. Residentstheresidents their go The academic through rotations offer the rotations throughout and other skills. thinking critical develop that reports individualized morning group, literature-based, small conference; as well week as of teaching the department-wide case featured weekly the and morbidity series, and mortality the series, medicine context based of the evidence our in traininglectures mentors academic as for serve resident-prepared also group faculty presentations. large are Select conference didactic offered noon rotation, each through residents and educating during including ways, important in Program Residency the as electives. to contributes substantially Department Pediatrics the in division psychiatry. Each and medicine family medicine, emergency anesthesia, in trainees visiting 200 as than more as house well officers, LearningChildren’s Center pediatric Medical members to Southwestern to – 100 provide our UT experiences broad deepeducational faculty and of Pediatrics clinic-based the Department with Center Children’sat partners Program Residency Southwestern Medical UT The Pediatric Resident Education Parkland Memorial Hospital where there are about 15,000 admissions annually and where and she annually about Hospital where Memorial are admissions there 15,000 Parkland at nursery newborn the in pediatrician attending an isas practice Southwestern. Her clinical poor. at UT of Dr. 15 Pediatrics For past years, Department the worked Sendelbach has the in for indigent working the and clinic city inner an in pediatrician care aprimary by as seven years Children’s 1985. Center in emergency Medical Sheroom, briefly worked apediatric in followed She completed Newark. School in New her from She Jersey residency graduated at Medical Rutgers University. from engineering chemical in degree Director, herundergraduate received Dorothy Sendelbach, M.D. 2010-2011 Residents , Associate Professor of Pediatrics Associate and Program Education 17 Mindy Calandro, Diana Mindy Calandro, . The chiefs. The heavily are involved The 2010-2011 Chief Residents were were Chief Residents The 2010-2011 Dickschat and David Troendle Dickschat David and activitiesin the day-to-day the of program and serve as a liaison focused facultyamong Chief resident and residents. members substantialto led efforts have department- development project in officer house training,wide improvements process patient safety, and the line front use medical of literature and evidence based medicine. , Assistant Professor of Pediatrics and of Associate, Assistant Program Professor Director, Innovations in BioMedicine (NEW) – serves as a research interest group. The residents meet regularly to discussresearch articles with invited faculty as and presenters. fellows members discussed (NEW)Advocacy – topics and Medicine in Transnational Group this Community include group Needs Assessments, Maker Policy Interactions, Local Partnerships Resource and Sustainability. Advocacy Project The and Christina M.D., Nancy by is lead Bourland,Advocacy Kelly, and Medicine Transnational M.D. Group Primary in interested primary Care residents Pediatrics for – the serves care group pediatrics an avenue learn to leading the field primaryabout from healthcare public and physicians. Incorporation of iPod Touches Touches iPod of Incorporation the program residency a shift created medical In how 2010, in house officers,to is delivered information through the Touch iPod The Touch. iPod serveruse a dedicated and of medical officer’s network, each house computer education access to key teachingallows residents videos, continuity clinic curriculum, and archived our resources state-of-the- art medical library Delivering manner. efficient with key inresidents to a timely, a information oftheswipe finger care patient and safety. improve to continues t t t To programresidency residents. The for to see continues the the importancemedicalof development group interest guide these make developed, interests, a total were two groups three interest new of groups: 2010 saw several saw the to updates program. Feature examples are: 2010 Groups – Interest Development Talent Resident Dr. McKinney, in his second year as Program Director, saw a reduction in resident work hours, mandated by the hours, mandated by work in in year resident a reduction his as saw McKinney, second ProgramDr. Director, The in section). Chief (detailed Projects the by chief lead residents were schedules ChangesACGME. in resident mandated in reduction duty will hours also learn, their skills. residents and impact develop professional how Pediatric Residency Enhancements Program Pediatric Lauren Gore, M.D. Gore, Lauren serves asMedical Director. Her interests include breastfeeding promotion, jaundice screening, neonatal abstinencesyndrome and pulse oximetry screening. 2006, Since has Sendelbach served asDr. an Associate Program Director the Pediatricfor Residency Program and is the primary program, internal the of leader for mentorship program medical is part She mentoring student reviews, UT electives of new and Southwestern’s and creation development. for all among asprogram, the and 2009 the was Parkland of honored Year Physician physicians. received her undergraduate degree from Texas A&M University. She graduated She from UT A&M University. undergraduate her degreereceived from Texas UT at residency her completed Gore Dr. M.D. her received she where Health Center, Science also She servedSouthwestern in during as 2007. Chief which Resident sparked 2007-2008, true serves her Gore of passions, and is one Dr. Mentoring education. in interest resident her and guides the to residents PL3 as the through a mentor chief residents their has She year. participated in recruitment of the new intern class, program development, continuity clinic and in-depth M&M, advocacy Her and projects. duringlogistics, residents CAT, and mentoring nuanced understanding flow and care patient former of systems,as a honed UT - Southwestern safety patient integration ACGME this of improved year’s profoundly Medical have Chief Resident Center Children’s mandates the into system. Education 18 late in the third year. third the late in a project beginning than rather effort” project year a “three this of making goal the project advocacy with wide a class implementingand designing time on how of great begin to deal a also focused The retreat patient’s these families. with in-depth session with the interns regarding how worker Boston from social Children’s medical who an isamedical Browning, Hospital, patients. David among our facilitated professionals deal not only with terminal dying process the and death patientswith haswhich to do in pediatrics decided onissues to focus one more of the difficult but also about discussion process as well improvement. as fromprior of light suggestions building, residents, In it also was on spent team was retreat working at the time prior year. in years, the As throughout haveevents that transpired for professionalan developmentalwaysopportunity been time forthe internas on has reflection The retreat as well Retreat Intern sessions. therapy and various evaluations, speech array of classroomwide environments, a seeing differences learning with the Shelton at time School spendto managementfor of children ADHD.the have The also opportunity residents had and diagnosis the in who specializes area Dallas the in aprivate pediatrician spent with sessions also are clinic Several concern for autism. with process of achild evaluation and intake entire the observe where they Autism clinic Ball Charity Crystal the time at population. alsospend The residents the pediatric in about difficulties feeding learn as well groups,as therapy autism various in Center for participate disorders where communication they Callier at the Residentstime as spendthe well. from awayhospital opportunities haveThe chiefs a designed of number learning clinic. neurodevelopmental the presents, disabilities and population patient unique this issues developmental unique the understanding clinic care foster and adoption time in a number of CMC clinics including low birth weight observing Bayley’s metroplex. Residents spend Dallas the schools in and developmental of clinics residents the avariety now in Children, spend time exams, international wantedthey rotation. to during this gain spending Rather most than of block the at Texas Rite Scottish Hospital for evolved changes year. resident from for requests of and Many these experiences this suggestions number of changes the second of residency,year place undergoneduring Therotation, takes developmental has which a pediatrics /DevelopmentalBehavioral Rotation Changes The enhancements. 2010 the Program: chiefsprogram into specific the have incorporated following achieving residents day-to-day chief to the have leaders, role roles teachers, and beencentral as essential models, Beyond their Resident Projects Chief t t t t t t year: the throughout initiatives following on the focused Dr. also McKinney residentsthe to bemore patients. their advocates completefor effective, and allow in Children’sCenter. for the thehoused lawyers concerns to Medical The services patients, reporting affect that determinants social The andresidents identify screen services. need of legal in families patients and those identify to trained The residents have setting. now beensuccessfully medical into the services legal by integrating families The Medical-Legal Partnership Partnership aimsMedical-Legal to improve the health and well-being of vulnerable individuals, children and Candidates To Dallas Candidates /Children’s Southwestern Center House UT Officer Tactics Medical and to Attract Strategies Novel Recruiting Community Advocacy Training program the Stone –Incorporation of Rosetta within Skills Language Spanish Medical treatments and patient evaluation pointsin branch of decision key discussions Week of the Case faculty Conference,Department inter-service to include real-time Conference Series Morbidity Analysis Root and Cause ResidentSenior Mortality Sessions Citation Training Clinical and Search Literature Medical Intern Education 19 Joel Steinberg, M.D. Myra Wyckoff, M.D. Myra Wyckoff, Jennifer Walsh, M.D. Jennifer Walsh, Maeve Sheehan,Maeve M.D. Dorothy Sendelbach, M.D. Sendelbach, Dorothy Becky Ennis, M.D. Lauren Gore, M.D. Gore, Lauren Pamela Okada, M.D. Raymong Quigley, M.D. Quigley, Raymong Nancy Kelly, M.D., M.P.H. M.D., Nancy Kelly, Matthew M.D. Cox, Laura Brumley, M.D. Brumley, Laura Soumya Adhikari,Soumya M.D. Maite de la Morena, M.D. Maite de la Morena, Christina Bourland, M.D. Bourland, Christina Thismeetsmonthly withgroup Departmentthe Chair and Programthe review to Director resident’s or each intern progress and career development. In 2010, 15 faculty 15 served members as mentors: In 2010, The mentor is not necessarily intended to be an expert specialist in the particular field of subspecialty training that that training subspecialty of field particular the in specialist expert an be to intended necessarily not is mentor The general counsel and oversight, guidance focus provide is to the mentor’s pursue. Rather, to choose may a resident pertinent the to individual as pediatrician. a wellwell in rounded developing the of are process mentors The withinpositioned all connections the to department broad have subspecialty to areas is interested so that if a resident in pursuing a particular path with some specificity, such as a research block, interactions. that mentorsuch is of assistance in arranging A central element of theA central of Pediatric Residency element Program is its longitudinal actively every to provided mentorship resident. program was mentor established The in 2004 to and increase the individualized development resident to approach pursuit of educational goals. A mentor is assigned to a resident during intern orientation, and that resident/mentor dyad throughout continues the three years training. residency of relationship one-on- residents the allows mentor The interactionone with a faculty that member guides evaluation them career review, through development, residency, and guidance through individual projects. residents’ Mentor Program This past year, a new objective oriented ethicsoriented newobjective a This curriculum pastyear, was successfullypiloted. The and developed curriculum utilizes frequently meeting small longitudinal groups, and case based learning mentorship, residents equip to sessions with necessary tools analyze, identify, to ethical and resolve issues in clinicalprogram medicine. The looksforward utilizingto this curriculum aid training to inbased, of years our mission come ethical to principle for compassionate, the of future.physicians Ethics Curriculum Educational Library theLast program residency year, began that deliver high would working a project on quality educational materials well as procedures, demand. on This residents yearto a delivery system wasto access developed that a residents library allows of sentinel preformed commonly of campus, their on literature on videos or Touch iPod and any training computer videos their computer, be on whether it home training Stills, and Kawasaki original containsIt historic The classic of library bedside. descriptions diseases to grow. continues theat patient’s Addison, as such physicians from as contemporary articles with care help to making. of point decision This of library residents appreciation teachesan the literature and allows them practice to evidence effectively based medicine on more efficiently thefrontlines.and Schedule Changes Schedule A significantof time amount thisyear redesigning was spent program residency the structure in of new light the call regulations. dutyhours of that hours than the Given ACGME regulations new for more in no allow 16 a row for and greater than no changes a number of call that there of be implemented 24 hours to were PL1s needed 2/3s, PL for the program. residency beginfor to In order redesigning the of process the the program, residency for schedule the programlist made a leadership important of this goals for restructuring limited not to, were which but included, enhancing limiting the educational value residency, of handoffs, the patient number of preserving and exposureto a vast array pediatric of clinical diagnoses. Education 20 invested more than 1,000 hours in interviews alone. The core interviewers alone. Thewere: coreinterviewers interviews hours in 1,000 invested more than graciously of acandidate’s faculty application. analysis extensive Our an providing but also candidates, interviewing not season, only recruitment the during responsibilities their increased Core interviewers experience. research and talents advocacy skills, diversity, of widerange 2012 a language year.brings intern class academic The new positions offered newthe2011- interns 34 for with saw interviewed, a15% applicants recruitment Intern in increase Intern Recruitment t t t t t t t Implementation /completion project of advocacy t Community pediatrics rotation Samples 2010-2011 of the forallowed culturally. improvements and hospital, community the in projects are: advocacy the community.SeniorThe in Residents Many projects completed many needs project that addressed projects advocacy advocacy Selection Program) Legal (Medical activities Care First session retreat Intern Thirdthem affect of patient that issues Diary Adolescent Year Second activity Year Intern t t Year t t t t includes: curriculum advocacy the Bourland Christina and Kelly of Nancy Under Drs. direction the curriculum. advocacy an to now but project, advocacy an completing residents just than more to advanced has Advocacy Curriculum Advocacy Paul Harker-Murray,Paul M.D., Ph.D. Michele Hutchison, M.D., Ph.D. Cindy Darnell, M.D., M.S.C.S. Darnell, Cindy Carolyn Cannon, M.D., Cannon, Ph.D. Carolyn STAND – Smart Teens STAND Drugs –Smart Nicotine and Against school volunteers hospital youth and high education with and experience Shadowing its complications and –marijuana Abuse Substance Care Palliative education support) and limited moms with teen with working populations Prevention Abuse (specifically risk parentChild project education high in through of Syndrome to parents about Down anew diagnosis Resident education on talking Asthma and Obesity with dealing Community Dallas the in families for and patients, practitioners, Resource guide Texas Cord Blood Banking Year Specific Activities Advocacy Newsletter Work Leaders Resident Advocacy with Group Interest Advocacy Web Learning Based Noon Conferences Nancy Kelly,Nancy M.D., M.P.H. Christina Bourland, M.D. Vijay Kalidindi, M.D. Vijay Kalidindi, Leticia Castillo, M.D. Bradley Barth, M.D. Barth, Bradley Shelby Joseph, M.D. Matthew Cox, M.D. Matthew Kathryn Ban, M.D. Ban, Kathryn Lauren Gore, M.D. Jennifer Cox, M.D. Lina Chalak, M.D. Mark Clay,Mark M.D. Tanya Martinez-Fernandez, M.D. Tanya Martinez-Fernandez, Jeffrey Jeffrey McKinney,M.D., Ph.D. George McCracken, Jr., McCracken, George M.D. Laura Klesse, M.D., Ph.D. Klesse, Laura Laura McClendon, M.D. Timothy McCavit, M.D.Timothy McCavit, Marilyn Punaro, M.D. Punaro, Marilyn Vineeta Mittal, M.D. Mittal, Vineeta Pamela Okada, M.D. Okada, Pamela Benjamin M.D. Lee, George Lister, M.D. Karen Latour, M.D. Joshua Koch, M.D. Ashish Patel, M.D.Ashish Emily Osier,Emily M.D. Reina Patel, D.O.Reina Norberto Rodriguez-Baez, M.D. Rodriguez-Baez, Norberto Elizabeth (Kaili) Stehel, M.D. (Kaili) Elizabeth Dorothy Sendelbach, M.D. William Scott, M.D.,William M.S. Bharath Thankavel, M.D. Thankavel, Bharath Catherine Robben, M.D. Robben, Catherine Marita Thompson,Marita M.D. Martha Stegner, M.D.Martha Meghana Sathe, M.D. Sathe, Meghana Laura Wolovits, M.D. Jennifer Walsh,Jennifer M.D. Pablo Sánchez, M.D. Sánchez, Pablo Myra Wyckoff,Myra M.D. Zora Rogers,Zora M.D. Philip Shaul, M.D. Shaul, Philip Education 21 , Sylvia Trevino, Rita Linda, Sylvia Trevino, Byrd, M. Gander, Pranavi Siegel, Jane D. Sreeramoju, , Christina Sakai, Rashmi MD, Shetgiri, at Presentation MD Poster and MD. Glenn Flores, , Carrye scintigraphy Cost, in bone osteosarcoma, Kevin of a Use Cederberg, Patrick Leavey. , Soumya Adhikari, Smith, Perrin Joshua Neonatal C. Hypocalcemia: White. Transient . Studying hepatobiliary transport and hepatocyte regulation cell volume in the Dr. lab of . Poster Presentation. American Presentation. . Poster “Progression Society Oncology Conference. Hematology of , Vineeta Mittal, Benjamin Lee, Benjamin Martin, Rashmi Reina Patel, Shetgiri, Glenn Flores. J Sanchez, Alicia, Pablo Guzman, Nancy Miller. Diana Pediatric Vasil, Academic Societies , Carla Lee, Garcia, Michelle Gill. Wai-Ming Spectrum Disease of Associated with the . Single Balloon Enteroscopy to Confirm Crohn’s Disease in a Pediatric Patient. Poster session at at Disease session Poster Pediatric . Single a in ConfirmPatient. to Balloon Enteroscopy Crohn’s Presentation and Outcomes. May 2010. Poster Session: Endocrine as Session: a Data was Clinical. Poster presented 2010. 2010. May and May Outcomes. Presentation meeting in Vancouver. PAS the at 2010 poster presentation Margaret Trost NASPGHAN Annualthe Meeting 2010 (North American Hepatology, Society Pediatric Gastroenterology, for October 2010 and Nutrition). Jacquelyn Powers (American Society Oncology). Pediatric ASPHO Hematology of at presentation single Poster institution review. April 2011. Hanners W. Natasha faecium Enterococcus (VRE) Mambarath Sanchez. A. J. Jaleel, Vancomycin-Resistant Eradication and of Pablo Describing the (NICU). Care clinical Unit from a Neonatal Intensive characteristics infants of colonized with VRE maternal in characteristics our NICU, those of infants the and outbreak. interventions used control to meeting. PAS 2011 at presentation Poster Carlos Oliveira Andrew that Feranchak, release hepatocyte studies ATP regulation cell on 1) demonstrated volume is dependent and purinergic signaling, that fatty 2) cells liver altered regulatory cell have volume mechanisms stemming that this and with altered regulation 3) cell can volume be overcome a decreasefrom ATP, in of secretion meeting in PAS the at 2010 as presentation a platform Data was presented the extracellular addition of ATP. Vancouver. C. Thomas Teena Diagnosis Rhinovirus of as a poster Data was Medical presented Dallas. of Center Children’s’ at 2010. May meeting in Vancouver. PAS the at 2010 presentation Anna Miller American Medical for Federation Research Southern Regional Family-Centered “Do Meeting. February 2011 satisfaction, parent hand-offs, care, communication, outcomes, coordination of safety, Rounds improve patient and trainees A qualitative hospitalized study education? of parents of children.” Sara Franzen, MD ‘Bridging Conference the Mental Healthcare Gap of Perspectives Adulthood: to in The the PAS Transition 2011 Emancipated Foster-Careof Youth’ Carlos Oliveira Abstract title: Race and Ethnicity 2011: Denver with Mothers of presentation SpanishPoster Surnames Amy MD Walz, Laura Klesse. 2011 Survival Mentor-Dr. in Lesions Free Children.” Plate Tectal of and Outcomes David Troendle Working title: Targeted ablation of dividing of ablation title: neural Targeted Working crest cells during cardiac tract outflow formation. Associate Kernie, Professor MD, Steven Mentor: Summary: During cardiac mid-gestation, neural crest cells migrate cardiac the to developing tract outflow truncal to theywhere contribute a transgenic to and Using are septation valve able we model formation. mouse selectively kill actively dividing neural crest cells, thus allowing disruption during outflow tract of formation a well-defined temporal period. The to define teamhoping acritical is of neural period crest cell which, division if disrupted, will a phenotype similar produce truncus persistent to arteriosus. Dr. Matthew Fletcher, along with Dr. Tim McCavit, Assistant Professor in Pediatric Hematology-Oncology, along with Tim McCavit, in Assistant Matthew Pediatric Dr. Hematology-Oncology, Professor Fletcher, Dr. in a study involved examiningwere the effect of timing administration of antibiotic in febrileoutcome the on studyretrospective The population. is a neutropenic chartreview of withall presentingto Children’s patients and betweenfebrile neutropenia 2001 2009 the purpose for evaluating of if the timing from presentation until the firstof parenteral dose pediatricsantibiotics among affectsoutcome patients with febrilecancerand 4, 2011 - June abstractneutropenia. and Drs. the Fletcher McCavitt’s ASCO Convention was for accepted t t t t t t t t t t Presentations Presentations t Paul Tannous, M.D., Ph.D. M.D., Tannous, Paul Matthew Fletcher, M.D. Fletcher, Matthew t Resident Projects 2010-2011 Academic Year Academic Projects Resident 2010-2011 Research Education 22 t Miller Heather Certifcations t McKey Joanna Publications Helping Babies Breath Certification as Instructor.2011as Helping Babies Breath Certification for Boards. Review and Guide Study Medicine J McKey ., Dimeff R. (in press 2012). Chapter42: Sports allergy and immunology. In: Harrast M., Finoff J. Sports M., R. FinoffJ. Sports 2012).., press Dimeff immunology.(in and Harrast In: allergy Chapter42: Sports 2010 Graduating Residents Education 23 2010 Graduating Fellows Graduating 2010
based approach encountered The Department of Pediatrics participate to fellows in national and local activities encouragesthat will enhance their UT education. Southwestern’s its subspecialty been recognized have their fellows for accomplishments and academic potential receiving by awards and grants Several also many competed sources. from fellows have successfully from the Pediatric fellowships Scientist for To facilitate the these pursuit of goals,To each division has a training program the that clinical provides experience traineesand for research environment be exposed to scientific to be meansinvestigation taught and the to translate inquiry All scholarship. into subspecialty Review the Residency by reaccredited programs were Committee in the 2008 of ACGME and contain clinical with inand experiences accordance research the guidelines set forth by the American withIn compliance these guidelines, each trainee has Board of Pediatrics. a Scholarship Committee Oversight that assists the Program Directors in each research trainee’s monitoring experiences. 2. Provide analytical skills and critical thinking necessary to confront conditions they may not have previously 3. care a desire advance to through knowledge and Engender improve research and teaching 1. 1. Prepare future subspecialists cognitively and technically practice to their disciplineusing proficiently an evidence- The department,The opportunity sees therefore, in this changing educationalrealizingKeyto environment. this opportunity is acknowledging that subspecialty training three accomplish must goals: During 2010 there were 97 subspecialty there were During trainees 2010 within preparing on value is placed the various divisions. Tremendous these pediatricians young undertake to careers as clinician-investigators, teachers, subspecialty consultants and, more generally, as contributors to the growing body of knowledge in pediatric medicine and developmental biology. is viewed as education theFellowship first most importantand step in the transfer of academic to the next mission the last The decade has been generation. associated with a substantial by change prompted postgraduatein education, the recognition system that often shortchangedof the apprenticeship “old” education the the trainee in of the interest providing clinical service. This hasresulted in guidelines that guarantee the integrityof educationalthe environment against the demands that the changing healthcare landscape has been applying academic Although on centers. the thesespirit of guidelines the the by academic balance community, has been welcomed between clinical responsibility remainsand education an issue that is in flux. In January 2005, the departmentestablished an interdisciplinary program subspecialty for objective, The a education. a departmentalin progress, develop is to work educational and of administrative repository and resources experiences enrichto the opportunitiesby offered the individual subspecialty trainingprograms. program The Dr. is by directed than has years who more Rosenfeld, experience 35 in postgraduate and with research, education in conjunction the Program Directors, other faculty and, very the activities importantly, Central fellows. the to program’s is a bimonthly and discuss explore designed to institutionalconference to examine resources, needed and requirements approaches initiate clinical and research, laboratory plan a career faculty research by and make ongoing career present choices, social for interaction a site andand and discussions fellows, provide between trainees all from subspecialties. The curriculumprogram required core is unique the in of ACGME that much can be achieved in a manner that best meets the each trainee. needs of Fellow Education Education 24 critical review from their peers and the faculty at an early stage in their research efforts. research their in stage early at an faculty the peersand their from review critical order in to receive timely core of the curriculum second the half in presented research their trainees Second year development. for career opportunities Awards presentations. were oral posterand for given best the identifying Washington University School on of of Pediatrics, Medicine, Chairman apresentationand Schwartz, by Dr. Alan directors division and mentors, directors program trainees, for all was This the followeddinner faculty. by by a reviews abstract after chosen thelatter presentations, presentations fiveposter and oral of a Senior Fellows’ Day on Research May 25, 2010. There were 18 establishment the was Programs A notable Training our in change September. and August in trainees 2nd-3rd 1st the of needs and the year individual to meet year the conferences have Separate Southwestern. at beenestablished UT The future of pediatric senior year. their during meetings or international national regional, groupalso presented at This abstracts 51 training. to completing their subspecialtyPediatrics) eighteen published and peer-reviewed prior manuscripts training fellowship project research Academy (e.g., oftheir American the fellows, 35% for graduating received the peer-reviewedOf continues funding practice. entered into clinical trainees remaining the while research, to change training/ chose to do additional Notably,Southwestern. trainees three at UT 53% faculty on the schools, with remaining medical various in June 2010. in positions academic assumed the 26 Fifteen of training completed Twenty-six their Department 97fellowship of trainees the ofhelp promising careers launch trainees. the Patient-Oriented in to Research aCurriculum and Program created aPhysician-Scientist has Training Southwestern UT end, to this career; physicians talented to develop academic an assisting and to encouraging committed School are and Medical K-awards mentored The Department and or analogous NIH grants. Program the research from Training Closure of the Ductus Arteriosus in Neonates inNeonates Arteriosus oftheDuctus Closure Echocardiograpic Prediction of Spontaneous ofSpontaneous Prediction Echocardiograpic Poonam M.D. Punjwani, Best Poster Presentation Best Division of Pediatric Cardiology Pediatric of Division less than 30 weeks Gestional Age Gestional 30weeks than less MicroRNA-21 Drives Non-small Cell Lung Cancer Cancer Lung Cell Non-small Drives MicroRNA-21 Tumorigenesis through the Relieving Inhibition Tumorigenesis of theRelieving through Division of Pediatric Hematology-Oncology of Pediatric Division the Ras Pathwaythe Ras andInhibiting Aptosis Mark Hatley,Mark M.D., Ph.D. Best Oral PresentationBest Oral Micah Olson, discusses his research project with with research project his discusses Olson, Micah Pediatric Endocrinology graduating fellow, Dr. graduating Endocrinology Pediatric keynot speaker, Dr. Alan Schwartz, atthe1st speaker, Dr. Schwartz, keynot Alan Annual Fellows’ Research Day. Allergy & Immunology
25 . She recently. She Director, Pediatric Allergy & Immunology Pediatric Director, Rebecca Gruchalla, M.D., Ph.D. Rebecca Gruchalla, M.D., Journal of Allergy and Clinical Immunology in North Texas. North in Allergy & Immunology & Allergy Our newly opened Food Allergy Food is the opened Center Our newly only academically affiliated pediatric affiliated food allergy academically program only degree in 1985 from UT Southwestern and her Bachelor of Science degree from from degree Science of Bachelor Internal of Rebecca Medicine and Gruchalla, Professor Pediatrics, is Ph.D., M.D., her and the Allergy Division Chief of and Immunology of UT at and Southwestern holder Southwestern the William A. UT M. Sellars, Sellars and Joyce Distinguished M.D. Chair in Allergy from and medical in her Immunology Ph.D. in her 1981 received She and Immunology. 1985 in degree Gruchalla her Dr. completed in 1976. Texas, Lubbock, University, Tech Texas Pennsylvania of in University of Hospital the The at in Internal Medicine residency Philadelphia training and fellowship in her 1988 in Allergy and Immunology UT at clinical Gruchalla’s inSouthwestern Dr. 1990. interests are focused anaphylaxis, on asthma, drug allergy, mastocytosis and urticaria. clinical In her addition to activities, Gruchalla(NIH)-funded Dr. is principal theHealth of Inner investigator City Asthmaof Consortium, Dallas Institutes National multi-site a is Consortium This site. consortium that is performing both clinical and mechanistic studies pertaining pediatricto inner-city Gruchalla asthma. with Dr. was the In honored 2007, Gail in the Involvement MemorialG. Shapiro Lectureship the and received Women’s American Academy of Allergy, Asthma and Immunology Special Recognition currently She Award. serves the on Board Directors the of of American Board Allergyof and Immunology and the on Editorial Board the of term the on Board Directors the of of American a four-year Allergy, of completed Asthma Academy and Immunology. Faculty Furthermore, the Immunology Program is committed and physicians other healthcare the of to education providers, trainees, the general and patients public, families regarding diagnosis, manifestation, natural history and treatment primaryof immunodeficiency diseases. In asthma addition to research, the Clinical Immunology Program UT de la Morena, at directed Southwestern, Dr. by was recognition the awarded by JeffreyModellfor of diagnosis Foundation Excellence as a of Center and treatment primary immunodeficiency diseases. The Immunology Program serves a large geographic referral eastern Oklahoma,North Mexico, New area Texas, encompassing western Louisiana and southern Arkansas.program This comprehensive both diagnosticprovides and state-of-the-art opportunities treatment with patients for primary immunodeficiency diseases. Dr. David KhanDr. is the Program the Director of Allergy and Immunology program. fellowship Both and he Dr. Rebecca Gruchalla, see adultsand children Division Director, with asthma and allergic the at Center disorders Aston UT Southwestern. at participateto The continues division bothin clinicalresearch efforts. science basic bothand As a clinicaland a expandmechanistic to continues in research its efforts it the site Inner City pediatricin Asthma Consortium (ICAC), asthma. The division also collaborates with on various Drs.campus: scientists Gill, basic Michelle Nitin Karandikar and David Farrar. The The Allergy and Immunology division in DepartmentPediatricsthe of wasyears eight established approximately ago. Originating in the Department Internal spans of both Medicine, now it departments, with Pediatric-based andfour two Internal Medicine-based faculty each board members, certified in AllergyPediatric and Immunology. allergist specialists, Andrew and J. William Bird Drs. Indulekha Warrier, Neaville see children with allergic and disorders asthma staffing Children’s, eleven at allergy hasMorena clinics established Dr. week. de la per Maite In addition, a primary sees She immunodeficiencyprogram for allimmunodeficiency consultations at Children’s. inpatient anddisorders has three clinics during per week evaluates which she these patients. Allergy & Immunology 26 Education: development of oral tolerance expertise: Clinical/research Dedman Family Scholar inClinicalCare Assistant Professor, Pediatrics and Internal Medicine John Andrew Bird, M.D. Fellow, and Immunology, Allergy 2007 Clinical Pharmacology, 2003-2006;Fellow, and Immunology, Allergy 2005-2006;Research Hospital of Michigan, Wayne State University, Detroit, Resident, Pediatrics, 1994-1997;Fellow, Government BJMedical College, India, Graduate Student, Radiology, 1991-1993; Children’s 1990-1991; Ophthalmic Hospital, Trivandrum, India, Graduate Student, Ophthalmology, 1991; Post-doctoral training: Education: expertise: Clinical/research Assistant Professor, Pediatrics and Internal Medicine Warrier,Indulekha M.D. Fellow, and Immunology, Allergy 2000-2003 Hospital, Little Resident, Rock, Pediatrics, 1997-2000;University of Wisconsin, Madison, Post-doctoral training: Little M.D., Rock, Sciences, 1997 Education: expertise: Clinical/research Clinical Assistant Professor, Pediatrics and Internal Medicine William Neaville, M.D. expertise: Clinical/research Director, Asthma Clinic,Parkland and Allergy Memorial Hospital Director, and Immunology Allergy Fellowship Program, UTSouthwestern Professor, Internal Medicine David A.Khan,M.D. Laboratory Immunology, 1994-1995 Pediatrics, 1989-1991;Fellow, and Allergy Clinic FL, Fellow, Immunology and Research, 1987-1988;Intern, Pediatrics, 1988-1989;Resident, Madrid, 1986-1987;AllChildren’s Hospital, University of South Florida, St. Petersburg, Surgery, 1983-1986;Hospital Gregorio General Maranon, Research Assistant, Immunology, Post-doctoral training: Education: expertise: Clinical/research Director, Jeffrey Center Diagnostic Modell for Diseases Immunodeficiency Primary Associate Professor, Pediatrics and Internal Medicine M. Teresa (Maite)delaMorena, M.D. Center, Durham, NC, ClinicalResearch Fellow, Food Allergy, 2008-2009 Pediatrics, 2003-2006;Fellow, and Immunology, Allergy 2006-2008;Duke University Medical Post-doctoral training: San Antonio, M.D., 2003 Education: nonallergic rhinitis and alternative therapies for chronic urticaria Medicine, 1988-1991;Mayo Clinic,Rochester, MN,Fellow, and Immunology, Allergy 1991-1994 Post-doctoral training: University of Arkansas at Little B.S., Rock, 1993;University of Arkansas for Medical University Complutense Madrid, De Madrid, Spain, M.D., 1983 Texas A&M,College Station, B.S., University of Illinois of School Medicine, Chicago, M.D., 1988 Medical College, Trivandrum, University of Kerala, India, M.B.B.S., 1991 Good Samaritan Good Medical Center, AZ,Resident, Phoenix, Internal Trivandrum Medical College Hospital and SAT Hospital, India, Intern, University of Arkansas for Medical and Arkansas Sciences Children’s Hospital ClinicoSan Madrid, Carlos, Spain, Research Assistant, Baylor of College Medicine, Houston, Intern TX, and Resident, Asthma, allergies, immunology, pharmacology Asthma and allergies Rush immunotherapy, anaphyl immunodeficiencies, transplantation Primary Food allergy treatment,Food allergy anaphy cum laude al Immunology, 1991-1994;Fellow, Clinical , 1999;UTHealth Center at Science axis, mood disorders inasthma, axis, mood laxis, eosinophilic esophagitis, Allergy & Immunology 27 generation generation Therapies for management of chronic chronic of management for Therapies Asthma and changes in the weather changes and Asthma Erin Clarke, M.D. Research Interests: Stephanie Regan, M.D. Regan, Stephanie Research Interests: urticaria Quality of life in food allergic patients in food allergic life of Quality Risk factors for subjective symptoms symptoms subjective for Risk factors Pooja Paranjpe, M.D. Paranjpe, Pooja Research Interests: Michael Alvares, M.D. Michael Alvares, Research Interests: polyps Nasal M.D. Leon Kao, Research Interests: predictive drug challenges; during with in adults food testing of value asthma or rhinitis chronic Immunopathologic changes in nasal polyps following systemic corticosteroids systemic in nasal following polyps changes Immunopathologic of the efficacysecond review of efficacychallenges; of drug and the safety of analysis Retrospective in T cell development microRNAs of Role Robert M.D. Silge, Interests: Research antihistamines in chronic antihistamines Allergy Clinic Allergy Clinic Allergy Clinic RN Specialist Coordinator Clinic Schultz, Data RN Research Immunology Santoyo Brooksie Clinical Specialist Tschoepe, & RNAssociate Maria Crain, Dolores APN Gonzales Allergy Cangzhuan Dong Data (Caroline) Elizabeth Allergy Grannon, Research Deborah Clinic Hardy Clinical Holly Immunology Associate Rebecca Nan Jiang Research Research Senior Nurse Lewis Brenda Kristen Malone, RN Allergy & Immunology Clinic Clinical Research Staff Clinical Research 1st Year 1st 2nd Year Eric Kovash, M.D. Eric Kovash, Interests Research Post-doctoral Fellows Fellows Post-doctoral 2010 Completed June Gene Devora, M.D. Interests: Research Allergy & Immunology 28 requested in cases of suspected drug-allergy, anaphylactic reactions and severe and asthma. reactions anaphylactic drug-allergy, of suspected cases requested in usually are Consults diseases. allergic forof patients isavailable with evaluation inpatient service consult active An one in evauluation setting. otolaryngological an as well as system, immunological and patterns sensitization have acomplete of clinics allergen To evaluation these patients campus. who seenin are care, or Legacy facilitate the per month Dallas isoffered comprehensive either at clinic One half-day chronic sinusitis. for patients care with (CASCADE) sinus clinic recently to provide established was Otolaryngology and A combined Allergy/Immunology outpatient the clinic. in performed also are food challenges and challenges procedures drug suchas to provideManagement Special programs acomprehensive severe for asthma. patients with management strategy Asthma Education and Providers educators work Asthma the from closely with asthma. management of patients with and for evaluation oxide the studies nitric exhaled as well for as isavailable spirometry Lab Function A Pulmonary administration. anti-IgEimmunoglobulin and - rush and traditional -both immunotherapy are offered services personnel. Other by performed trained are allergies for drug testing and testing hymenoptera venom food allergens, and allergy for environmental prick testing skin Procedures suchas allergy. drug and allergy sting insect food allergy, dermatitis, atopic rhinitis, allergic but management to, and including, not atopic asthma, ofevaluation various limited diseases, are per seenper An patientsmonthweek to care foraverageforprovide patients. 200 day of clinics half nine areThere diseases. allergic of the whole and manage spectrum isequippedoutpatientdiagnose to clinic Allergy and TheAsthma Allergy and Asthma Activities Clinical allergies. with food dealing life offor families the quality on class of acooking effects the understanding and allergy, egg with flu to achild vaccine the of giving safety the 2010 in performed examining studies included multi-center two trials accompany development that the changes immunologic peanut OIT. during to peanuts of desensitization Other (ICAC).Consortium Asthma Innerthe City of TheICAC over as part to receive five $56 investigates million years Southwestern Center UT among 11 Medical was asthma. by selected National in of institutions the Institutes Health basic science efforts and research its clinical Under both continues to expand division Dr. the Gruchalla’s direction, Research Activities Pediatric Infectious Disease and Internal Medicine, to understand the the to understand Medicine, Internal and Disease Infectious Pediatric Professor, Assistant Dr. Gill, Michelle He with isworking basis. amount on aregular the increasing and person isallergic the which food of to the amounts small involves ingesting that safely allergy (OIT). for treatment immunotherapy food experimental OIT isan Dr. peanut using oral Drewin astudy Bird five enrolled subjects Francisco.Children’s San University Hospital and of California, Mount School New of York, in Medicine Baltimore, Sinai Louis St. Denver, in University Health in Hopkins Johns Jewish National Washington,Center D.C., in Detroit, Ford System, in Henry Health Medical National Children’s Chicago, in Hospital Memorial Children’s conducted Southwestern, isbeing research atUT Boston University, administered by the Universitythe is development The influence consortium factors that asthma. of of Wisconsin-Madison. of environmental evaluation In longitudinal aprospective, include additionstudies to Ongoing children. urban in of asthma novel causes and treatments Allergy & Immunology 29 defect 1 Interferon-gamma 1 Hyper IgM 1 Chediak Higashi syndrome 6HYHUHFRPELQHGLPPXQRGH¿FLHQFLHV 6&,' Aldrich syndrome 1 Wiskott (HLH) Lymphohistiocytosis 2 Hemophagocytic In collaboration with Drs. Victor Aquino and Jennifer Cox of the Hematopoietic Stem Cell Transplantation (HSCT) (HSCT) Cell Stem In with collaboration Transplantation and the Aquino Jennifer of Hematopoietic Cox Drs.Victor cell transplantation hematopoetic primary received for have patients immunodeficiency 11 team Children’s, at diseases. All well. are doing Assisted by clinicAssisted Grannon by Holly than and personnel Elizabeth been seen in more the 500 have patients Tschoepe, clinics.outpatient The Immunologyprogram more currently150than establishedprimaryfollows immunodeficiency diseases. than More infusions receive 25 patients gammaglobulin of consultation services regularly. Inpatient for lastprovided evaluation immunodeficiency of available were 100week. consults More a are than seven days inpatient year. Directed by de Dr. la Morena, the Immunology outpatient clinic at Children’s serves as a referral center for primaryTexas,immunodeficiency Oklahoma, southern Northdiseases for Arkansas, Patients LouisianaMexico. New and with unusual or recurrent, persistent infections are evaluated an inherited for immune of disorder function. The clinic currentlydisorders has expertise all of management established for primary(>155 immunodeficiency disorders recognized). Referrals syndromes periodic states post transplantations and fever immunosuppressed evaluations for for also are seen in clinics. Immunology During the Center’s first year, Dr. Bird completed more more than 950 clinical Bird completed Dr. food first visits.Duringmore year, than 35 addition, In the Center’s challenges Food arelaboratory performed and when skin inchallenges 2010. conducted were testing left have uncertainty as whether a child to is allergic a particular to food. Small the amounts of potentially allergenic are food given in an and incremental hour the over doses child two is observed additional for hours. If the child has an allergic the from diet. a fullIf reaction, the the is removed food tolerate child to is able serving without a reaction, the is food the into child’s diet. reintroduced The MedicalThe grandopeningFood of Children’s AllergyCenter the set a high theCenter standard future for the excellence of Food of Allergy Program. wasnew made possible The withCenter support the theFamily Robertof Robert The Nancy H. Dedman, Foundation, and Dedman Jr. Foundation and RobertMrs. H. $2.35 Their Dedman,million Sr. giftconstructionsupported costsand additional infrastructure needs. event The attracted nationally recognized in leaders the allergy food Hugh Sampson Jaffe from Foodthe such field as Dr. Allergy Food The Allergy City. Collaborative is a partnership SinaiInstitute Medical Mount at between in York Center New Medical collaborative and Allergy The Food Center Children’s will Institute be (FAI). an keyhost annual to event inleaders allergy food research and advocacy. Food Allergy Food the Medical Allergy Food Children’s at 2010, In Center of September Bird, officially Drew which is directed doors. its Dr. opened by Center, is in withassociation Southwestern, UT multidisciplinaryThis center, the only academically affiliated pediatric food allergyprogram North in who patients care for As comprehensive such, the provides Center Texas. have been diagnosed with food allergies and conducts research that is instrumental treatments, in therapies and, developing a cure ultimately, allergies. food for staff Its works also tirelessly to region throughout the educate parents, healthcare providers, school personnel and community childrenstakeholders help to and families navigate the many challenges issue. health complex this with associated Allergy & Immunology 30 J. Bird, Andrew M.D. M.D., S.Gruchalla, Ph.D.Rebecca Major Administrative Responsibilities orLeadership t M.D. Khan, David A. t TeresaM. (Maite) de laMorena, M.D. t t t t t t J. Bird, Andrew M.D. t M.D., Ph.D.Rebecca Gruchalla, Director. Program isthe Khan David Dr. Immunology; and Allergy in one has for of 71 only division fellowship programs accredited the training training, resident to addition In fellows. for teaching didactic offering conferences clinical attend residents and rotation each disordersimmunologic areand of provided allergic to residents aboutthe beginning specific at Relevant articles of one faculty. supervision members of division the of the under the residentsPediatric clinics seeoutpatients our in t t t to: are elective of the objectives The students. medical residents, fourth-year for and isavailable pediatric elective Immunology and Allergy An inpatient of consultation service. the conferences part as and clinical departmental regular residents the in for pediatric the teaching directs and immunology and residents of basics allergy on for pediatric the the teaching didactic also provides It diseases. immunodeficiency and asthma diseases, allergic management with of children and evaluation the residentsin to pediatric the majordivision instruction provides Immunology and Allergy The Presentations/Teaching Activities and Drug Allergy Interestand Allergy Drug Section Member, American Academy of Allergy, Asthma and Immunology, Food Allergy, Anaphylaxis, Dermatology Member, American Academy of Pediatrics, and Immunology Allergy subcommittee Medical Director, Children’s and Allergy Immunology Services, Secretary, of Board Directors, ABAI Member, Editorial Board, Journal and of Allergy Clinical Immunology Member, of Board Directors, and American of Board Immunology Allergy (ABAI) Member,Board, Scientific BioinformaticsAdvisory Information SupportContract, DAIT, NIAID Director, Division of Pediatric and Immunology Allergy Meeting and Winthrop University, Winthrop and Meeting 2010 NY, Island, Long January Tests” Society Negative Skin “Rush Immunotherapy,” and with Allergy Rounds, “Allergic Grand Rhinitis 2010 March FL, Miami, Diseases, on Infectious Term the and System Premature of Immune the the Neonate,”“Understanding TheCongress International 14th Support Group, November Plano, TX, 2010 Eosinophilic Hope of Hands Esophagitis,” Eosinophilic of Treatment & Management in Advances “Recent a Family,” Affect “How Children’s2010 Food October Allergies TX, Luncheon,Women’s Dallas, Auxiliary Tyler, UT Rounds, Grand of Pediatrics Department Food Allergies,” September, 2010 Managing and “Diagnosing Worth, Fort Meeting, May 2010 for Allergist the Allergy Tolerance,” and Society, Desensitization Immunology and Texas“Food Allergy: Asthma, Annual 12th Allergy, 2010 February 2010 LA, New Orleans, Meeting, Annual Immunology and (SLIT) Academy Asthma doeImmunotherapy Peanut Trail of Allergy, Allergy,” American Up Build of Tolerance” Parents During and Children “Double–Blinded and Placebo Controlled Sublingual Life of (HRQL) Food-SpecificImmunotherapy “Impact of Related Oral Quality (OIT) on of Health 2010 February Hospital, Dallas, Texas Presbyterian Health “Advances Treatment the in of Rounds, Food Allergy,” Grand Education Institute Texas and Research Health 2010 February LA, New Orleans, Meeting, Annual Immunology Tolerance“Induction of Drug and Academy Procedures,” Asthma of Allergy, Symposium, American immunodeficiency. primary and food allergy allergy, drug urticaria, asthma, rhinitis, categories: allergic immunology and major allergy patients all from discuss and Examine how to upper conduct lower the and Learn acomplete including airways; exam physical immunodeficiencies; and primary asthma allergies, of diagnosis Develop differential aworking Allergy & Immunology 31 National Institutes of Health Pediatric Loan Repayment Program Award 2010-2012 Award Program Loan Repayment Pediatric Health of Institutes National Pediatrics of Academy American Fellow, Co-chair, ACAAI Allied Health Symposium Committee Symposium Allied Health ACAAI Co-chair, ACAAI Committee, Planning Directors Program Training Member, ACAAI Committee, Anaphylaxis Drug and Chair, Society Immunology and Asthma, Allergy, Texas Past-President, Immunology and Asthma, Allergy, of Academy American FADDA, Secretary, Member, Primary Immunodeficiency Diseases Committee of the American Academy of Allergy, Asthma and and Asthma of Allergy, Academy of Primary American the Diseases Immunodeficiency Committee Member, Immunology Fellowship Allergy Immunology and UT Southwestern Director, Program Allergy and Clinics Asthma Hospital, Memorial Parkland Director, Fellow, American Academy of Pediatrics of Academy American Fellow, (USIDNet) Consortium Network Immunodeficiency the U.S. for Committee Advisory Member, Primaryfor Immunodeficiency at UT Diseases Center Foundation Modell Jeffrey The Director, Medical Southwestern/Children’s and Asthma of Allergy, Academy Primary American Diseases Immunodeficiency Committee Vice-Chair, Immunology Moderator, American Academy of Allergy, Asthma, and Immunology 2010 Annual Meeting, New Orleans, LA Orleans, New Meeting, Annual 2010 Immunology and Asthma, Allergy, of Academy American Moderator, Center Medical Children’s Review Committee, Award Excellence 2010 Nurse Reviewer, J. Andrew Bird, M.D. Andrew Bird, J. Awards and HonorsAwards David Khan, A. M.D. M. Teresa (Maite) de la Morena, M.D. de Morena, la (Maite) M. Teresa Allergy & Immunology 32 Cardiology 33 Director, Pediatric Cardiology Pediatric Director, William A. Scott, M.D., M.S. M.D., A. Scott, William Cardiology received his medical degree from from his medical degree received completed pediatric cardiology completed training in Michigan and a 4th year training of at joined the joined faculty as a clinical instructor afterour completing cardiology fellowship joined us from Boston Children’s Hospital where she managed she the where Hospital registry Children’s us autopsy from joined Boston of completed advanced training completed in heart failure and cardiac transplantation UT at Southwestern. trained in cardiology and acquired advanced training in cardiac critical care at Emory University. specimens. will She educational curricula be developing trainees for all at and levels will clinical provide support in the laboratory. echocardiography program. will She be advancing skills her in cardiac imaging and supporting the echocardiography laboratory. UT in interventional catheterization. He will be conducting research in new stent technologies insupporting the addition catheterization laboratory. to His primary will role the support be to growing rapidly transplant service. He willHe attend in the cardiac care intensive unit. has a research in He interest neuroprotection. the Indiana University School of Medicine, Indianapolis, in 1982 and in 1982 and Indianapolis, Medicine, School of University the Indiana Chief 1984 and 1982 to from department in the Pediatrics was a resident Cardiology in Pediatric held a fellowship 1985. He 1984 to from Resident 1988. Dr. 1985 to from Michigan of the University at Electrophysiology and in the Best America database Doctors of inclusion by was honored Scott 2010. 2003 through from William A. Scott, M.D., M.S., Professor of Pediatric Cardiology and Cardiology and Pediatric of M.S., Professor M.D., A. Scott, William UT at Cardiology program the Pediatric of Clinical Sciences, is the Director clinical with electrophysiology, specializes in cardiac Scott Dr. Southwestern. management, defibrillator and pacemaker ablation, in catheter interests arrhythmia involves research His evaluation. noninvasive and syncope in neuromuscular involvement cardiac management, diagnosis and and heart disease,disease, variability congenital heart epidemiology of rate Notre of the University from graduated Scott Dr. device therapy. pacemaker the University Science in 1978 and of degree a Bachelor with Indiana, Dame, Science research in clinical of degree a Master with Ann Arbor, Michigan, of in 1988. He analysis statistical design and Faculty t %S5FKBT4IBI t %S "NZ +VSBT[FL Five new faculty new theFive joined division members in 2010. The The division actively participates in the training subspecialty students,of residents by and provided fellows, which is anda diverse talented cardiology all themselves training represent who the faculty, of major programs in the United States. The clinicalThe serviceprogram referral a benefitsfrom large base,including regional,thosenational from and international in sources Medical the addition to In with local collaboration population. Center, Metroplex Children’s construction Heart a new bring to of is under all way Center cardiac services of hospital, floor the one together on beginning with 20-bed a new CVICU last that year. opened Research is strongly supported by UT Southwestern’s main campus resources, including extensive core facilities for for facilities core extensive including resources, campus main Southwestern’s UT by supported strongly is Research evaluationgenetic and both surgical and catheterization large animal suites for studies. Clinical research is further the by Departmentaugmented Clinical of Sciences, with support services study design, for grant and preparation statistical analysis. The Division of of Cardiology Division The has threeprimary of areas advancingto focus: a commitment scientific discovery through clinical outstanding of pediatricand research; basic provision cardiac care; as physicians new and of the education well practicing as of support the throughoutongoing physicians the state. t %S4VSFO7FFSBN3FEEZ t %S.BSL$MBZ t %S1PPOBNćBOLBWFM Additional faculty recruitments support expansion to in the areas cardiac of transplantation, heart failure, critical and advancedcare, imaging noninvasive prevention are ongoing. Cardiology 34 Southwestern, Fellow, Pediatric Cardiology, 2004-2007 Post-doctoral training: 2001 Education: Research expertise: Research transplantation, fetal echocardiography. expertise: Clinical Assistant Professor, Medical Director –Heart Transplantation Aliessa P. Barnes, M.D. Interventional Cardiology, 2002-2006 Pediatrics, 1999-2002;Baylor Collegeof Medicine, Houston, Fellow, TX, and Cardiology Post-doctoral training: Oklahoma of College Medicine, Norman, M.D., 1999 Education: outcomes expertise: Research expertise: Clinical Assistant Professor V. Vivian Dimas, M.D. Fellow, Cardiology, 2005-2007;ChiefFellow, Cardiology, 2007-2008 Resident, Pediatrics, 2001-2004;ChiefResident; Children’s 2004-2005;Boston Hospital, MA, Post-doctoral training: Southwestern, M.D., 2001 Education: expertise: Research expertise: Clinical Assistant Professor D.Michael Day, M.D. Fellow, Pediatric Cardiology, 2006-2009;Fellow, Pediatric Critical Care, 2009-2010 2002-2005; ChiefResident, 2005-2006;Sibley Heart University, Center/Emory Atlanta, GA, Post-doctoral training: M.D., 2002 Education: neuroprotective agent undergoing cardiopulmonary bypass and aborted cardiac arrest, progesterone asa expertise: Research expertise: Clinical Assistant Professor Mark Clay, M.D. University Medical Hospital, Durham, NC, Fellow, Pediatric Cardiology, 1966-1969 Johns Hopkins Hospital, Harriet Clinic,Baltimore, Lane MD, Resident, Pediatrics, 1965-1966; Post-doctoral training: NY, M.D., 1964 Education: disorders expertise: Clinical Clinical Associate Professor Sarah D. Blumenschein,M.D. Hospital, Fellow, MA,Senior Boston, Advanced Imaging, 2008-2009 Pediatrics, 2002-2005;UTSouthwestern, Fellow, Pediatric Cardiology, 2005-2008;Children’s Post-doctoral training: College of Medicine, Temple, M.D., 2002 Education: hypertensionpulmonary arterial expertise: Research expertise: Clinical Assistant Professor Shannon E. Blalock,M.D., M.S.P.H. Southwestern University, Georgetown, B.S., 1996;UTSouthwestern, TX, M.D., Southern Methodist Southern University, B.A., TX, Dallas, University of Tennessee at Knoxville, B.S., Xavier University, New Orleans, B.S., University, LA, 1998;Emory Atlanta, GA, Wellesley College, MA,B.A., Un 1960;Cornell University of Notre IN,B.A., Dame, South Bend, 1996;Texas A&MUniversity Congenital heart disease, ECHO, Congenital disease, heart transplantation, cardiomyopathy, cardiac Interventional cardiology Pediatric cardiology Cardiac critical care Cholesterol, hyperlipidemia, congenital disease, heart obesity, lipid Fetal echocardiography, cardiac MRI, pulmonary hypertension arterial Transplantation, echocardiography Interventional cardiology and novel techniques, long-term operative post Endocarditis Neurodevelopmental abnormalities inneonatal and patients pediatric Maladaptive ventricular changes insystemic right ventricles and UTSouthwestern/Children’s, Resident, Pediatrics, 2001-2004;UT University of Oklahoma Health Center, Sciences Norman, Resident, Brown University, Hasbro Children’s Hospital, Providence, RI, University of Alabama Affiliated Hospitals, Birmingham, Resident, New York University, Hospital, Bellevue Intern, Pediatrics, 1964-1965; University of Arkansas for Medical Little Resident, Rock, Sciences, magna cum laude with honors iversity Medical College, New York, cum laude , 1992;University of , 1997;UT Cardiology 35 , 1994; Ohio State , 1994; Ohio State , 1992; University of of , 1992; University with honors ical impact of prenatal diagnosis prenatal of ical impact summa cum laude cum summa Albert Einstein College of Medicine, Bronx, NY, Resident, Pediatrics, Pediatrics, Resident, NY, Bronx, Medicine, Albert College of Einstein Northwestern University Medical School, Children’s Memorial Memorial School, Children’s Medical University Northwestern Children’s Hospital of Pittsburgh, PA, Resident, Pediatrics, 1996-1999; Pediatrics, Resident, PA, Pittsburgh, of Hospital Children’s Christiana Care Health System, Newark, DE, Resident, Internal Internal Resident, DE, Newark, System, Health Care Christiana Ohio State University & Children’s Hospital, Columbus, Resident, Resident, Columbus, Hospital, & Children’s University Ohio State Georgetown University Medical Center, Washington, DC, Intern, DC, Intern, Washington, Center, Medical University Georgetown Web-based distance medical education distance Web-based Cardiac development Cardiac Fetal echocardiography Fetal Echocardiography psycholog imaging, cardiac Noninvasive Epidemiology of congenital heart disease, childhood congenital of hypertension Epidemiology General pediatric cardiology, echocardiography, fetal echocardiography fetal echocardiography, General pediatric cardiology, Cardiac pathology, education pathology, Cardiac Noninvasive imaging including transthoracic, transesophageal and fetal and transesophageal transthoracic, including imaging Noninvasive Echo, fetal echocardiography, preventive cardiology, Kawasaki Disease, Kawasaki cardiology, preventive fetal echocardiography, Echo, Congenital heart disease, Congenital transplantation Congenital heart disease, fetal echocardiography, pediatric echocardiography heart disease, Congenital fetal echocardiography, Bucknell University, Lewisburg, PA, B.Sci., 1996; Loyola University, Stritch School Stritch University, Loyola 1996; B.Sci., PA, Lewisburg, University, Bucknell Pennsylvania State University, University Park, B.S. B.S. Park, University University, State Pennsylvania University of California, Los Angeles, B.S., 1991; University of Southern California of University 1991; B.S., Los California, Angeles, of University Lynchburg College, VA, B.S., 1970; University of North Carolina, Chapel Hill, Hill, Chapel Carolina, North of 1970; University B.S., VA, College, Lynchburg B.A., OH, Cleveland, University, Case Western University of Notre Dame, IN, B.S., 1960; University of Chicago Pritzker School of School of Pritzker Chicago of 1960; University IN, B.S., Dame, Notre of University Pittsburgh School of Medicine, PA, M.D., 1996 M.D., PA, School Medicine, of Pittsburgh training: Post-doctoral 1999-2002 Cardiology, Pediatric Fellow, Charleston, Carolina, South of University Medical Research expertise: Education: 2002 IL, M.D., Maywood, Medicine, of training: Post-doctoral Colin E. Kane, M.D. Kane, E. Colin Professor Assistant Clinical expertise: Education: Fellow, GA, Atlanta, Medicine, School of 2002-2006; Emory University & Pediatrics, Medicine 2006-2009 Cardiology, Pediatric Amy L. Juraszek, M.D. L. Juraszek, Amy Professor Associate Clinical expertise: Research expertise: University College of Medicine, Columbus, M.D., 1998 M.D., Columbus, Medicine, College of University training: Post-doctoral 2002-2005; Fellow, Cardiology, Pediatric Fellow, 1998-2001; UT Southwestern, Pediatrics, 2005-2006 Echocardiography, Pediatric Education: 1996 M.D., Los Angeles, School Medicine, of training: Post-doctoral 1999-2002; Cardiology, Pediatric TX, Fellow, Houston, Medicine, College of 1996-1999; Baylor 2002-2003 Imaging, Cardiology Noninvasive Pediatric Fellow, Catherine M. Ikemba, M.D. M. Ikemba, Catherine Professor Assistant Clinical expertise: Research expertise: counseling and perinatal cardiology echocardiography, Research expertise: Education: University, Hopkins Johns 1976; M.D., Richmond, Virginia, of College 1972; Medical M.S.P.H., Medicine, 2000 of Certificate Business in the MD, Baltimore, training: Post-doctoral 1978-1979; Chief Pediatrics, GA, Resident, Atlanta, 1977-1978; Emory University, Pediatrics, DC, Washington, Center, Medical National Hospital 1979-1980; Children’s Pediatrics, Resident, 1988-1991 Cardiology, Pediatric Fellow, Lisa C. Heistein, M.D. Professor Assistant Clinical expertise: Education: outpatient pediatric cardiology outpatient Research expertise: Assistant Professor Assistant Clinical expertise: Candace L. Gibbin, M.D., M.S.P.H. M.D., L. Gibbin, Candace Research expertise: David E. Fixler, M.D., M.Sc. M.D., Fixler, E. David Professor in Pediatrics Professorship Brooksaler S. Fred Dr. Clinical expertise: Education: M.Sc., Medicine, Tropical and Hygiene School of London of University 1964; M.D., Medicine, 1982 Epidemiology, training: Post-doctoral 1966-1967; Cardiology, Pediatric 1964-1966; Fellow, Pediatrics, Resident, IL, Chicago, Hospital, NIH Post-doctoral Institute, Research Cardiovascular Francisco San at California of University 1969-1971 Cardiology, Pediatric Fellow, Research Cardiology 36 Fellow, Echocardiography, 1995-1996 University of Colorado Health Center, Science Denver, Fellow, Pediatric Cardiology, 1992-1995; Post-doctoral training: Education: Research expertise: Research echocardiography, single ventricle palliation expertise: Clinical Professor Matthew S.Lemler, M.D. Pediatric Cardiology, 1992-1993 Hospital of Philadelphia, PA, Fellow, Pediatric Cardiology, 1989-1992;Fourth Year Fellowship, Francisco, Research Fellow, Pediatric Echocardiographic Laboratory, 1984-1985;Children’s London, England, Fellow, Pediatric Cardiology, 1982-1984;University of California at San of1987-1989; School Pediatric of Cardiology Institute the of ChildHealth, University of Resident, Pediatrics, University, 1979;Emory Atlanta, GA,Intern and Resident, Pediatrics, Hospital doEstado, dosServidores Rio deJaneiro, Resident, Pediatrics, 1978-1979;Chief Post-doctoral training: Federal do RiodeJaneiro, Brazil, M.D., 1977 Education: expertise: Research ventricular patent function, ductus inextreme arteriosus low weight birth infants expertise: Clinical Professor M.D.Claudio Ramaciotti, Children’s Hospital, MA,Fellow, Boston, Pediatric Cardiology, 1999-2002 Melbourne, Resident, Pediatrics, 1993-1995;Fellow, Pediatric Cardiology, 1996-1999; Post-doctoral training: Education: expertise: Research care expertise: Clinical Associate Professor Alan W. Nugent, M.B.B.S, F.R.A.C.P. Cardiovascular Research Institute, Fellow, Research, 1978-1981 1978; University of California at San Francisco, Fellow, Pediatric Cardiology, 1978-1981; Post-doctoral training: of Medicine,School CA,M.D., 1975 Education: for patients with congenital including disease quality heart of life expertise: Research student athlete pre-participation evaluation expertise: Clinical Professor Lynn Mahony, M.D. Research Institute, Fellow, Pediatric and Cardiology Neonatology, 1975-1978 Pediatric Medicine, 1973-1975;University of California San Francisco, Cardiovascular Post-doctoral training: New Haven, CT, M.D., 1973 Education: expertise: Research expertise: Clinical L.MooreRobert Chair inPediatrics Professor and Chairman, Department of Pediatrics George Lister, M.D. UTAustin, B.B.A., 1985;UTMedical Branch at Galveston, M.D., 1989 Universidade Federal doRiodeJaneiro, Massachusetts Institute of Technology, Cambridge, B.S., 1972;Stanford University Brown University, Providence, RI,B.A., 1969;Yale University of School Medicine, The University of Melbourne, Australia, M.B.B.S., 1991 Congenital heart disease, echocardiography, Congenital disease, heart non-invasive imaging, fetal Congenital heart disease, Duchenne Congenital muscular disease, heart dystrophy, echocardiography, congestive Congenital disease, heart failure, heart Marfan syndrome, Cardiopulmonary interaction Pediatric cardiology, interventional catheterization, cardiovascular intensive Aspirin resistance long-term inpediatrics, chemotherapy toxicity, sedation Congenital heart disease, echocardiography Congenital disease, heart Interventional cardiology and Clinicaltrials other studies examining short- and long-term outcomes Cardiovascular and hematologic development, SIDS Austin Hospital, Melbourne, Intern, 1992;Royal Children’s Hospital, Stanford University Medical Center, CA,Resident, Pediatrics, 1975- Yale University of School Medicine, New Haven, CT, Resident, UT Southwestern/Children’s, Resident, Pediatrics, 1989-1992, Universidade Federal doRiodeJaneiro, Intern, Pediatrics, 1976-1977; Brazil, undergraduate, 1972;Universidade Cardiology 37 , cum laude cum Institutions 11 Chair in Pediatric Care at Children’s at Care in Pediatric Chair
Vijayanagar Institute of Medical Sciences, Bellary, India, Intern, Intern, India, Sciences, Bellary, Medical of Institute Vijayanagar University of Virginia Children’s Medical Center, Charlottesville, Charlottesville, Center, Medical Children’s Virginia of University Mount Sinai Hospital Medical Center, New York, NY, Resident, Resident, NY, York, New Center, Medical Hospital Sinai Mount University of South Florida, Tampa, Resident, Pediatrics, 2004-2007; Pediatrics, Resident, Tampa, Florida, South of University University of Tennessee, Memphis, Residenty, Internal Medicine and and Medicine Internal Residenty, Memphis, Tennessee, of University Echocardiographic evaluation of the patent ductus arteriosus in neonates arteriosus ductus the patent of evaluation Echocardiographic Interventional cardiac catheterization and the role of interventional interventional of the role and catheterization cardiac Interventional Interventional cardiology, post-pericardiotomy syndrome post-pericardiotomy cardiology, Interventional Biodegradable stents for use in children for stents Biodegradable Cardiac MRI/magnetic resonance spectroscopy resonance MRI/magnetic Cardiac Interventional cardiology, cardiac electrophysiology, cardiovascular cardiovascular electrophysiology, cardiac cardiology, Interventional Interventional cardiology and novel techniques, congenital heart disease congenital techniques, novel and cardiology Interventional Echocardiography: 3D, transesophageal, fetal transesophageal, 3D, Echocardiography: heart congenital adult pediatric and cardiology, interventional Pediatric Adult congenital heart disease, heart failure/heart transplantation, heart transplantation, disease, heart congenital failure/heart Adult nationwide. Pediatric cardiologyPediatric faculty represent Columbia University, New York, NY, B.A., 1993; New York University School of School of University York 1993; New B.A., NY, York, New University, Columbia Wabash College, Crawfordsville, IN, 1977; University of Dallas, B.A., Dallas, B.A., of IN, 1977; University Crawfordsville, College, Wabash Vijayangar Institute of Medical Sciences, Karnataka, India, M.B.B.S., 2001 M.B.B.S., India, Sciences, Karnataka, Medical of Institute Vijayangar Eckerd College, St. Petersburg, FL, B.S. 2000; St. George’s University School of School of University George’s 2000; St. FL, B.S. Petersburg, St. College, Eckerd University of Missouri-Kansas City School of Medicine, B.A. and M.D., 2001 M.D., and B.A. School Medicine, of City Missouri-Kansas of University procedures and devices in congenital heart disease devices in congenital and procedures Education: Research expertise: M.D. Zeltser, Ilana J. Professor Assistant Clinical expertise: Clinical expertise: sports medicine syndrome, post-pericardiotomy screening, Research expertise: Education: 1997 M.D., Medicine, training: Post-doctoral Fellow, PA, Philadelphia, of Hospital 1997-2000; Children’s Medicine, Pediatric 2000-2003 Cardiology, Pediatric 2003-2004; Fellow, Electrophysiology, Thomas M. Zellers, M.D. M. Zellers, Thomas Professor Distinguished Kathryne Gene Bishop and UT Southwestern, Fellow, Pediatric Cardiology, 2007-2010 Cardiology, Pediatric Fellow, UT Southwestern, Education: training: Post-doctoral Resident, Flint, Center, Medical Hurley University/ State 2000-2001; Michigan Pediatrics, UT 2006-2009; Cardiology, Pediatric Fellow, University, State 2003-2006; Wayne Pediatrics, 2009-2010 Cardiology, Interventional Fellow, Southwestern, Surendranath Reddy Veeram Reddy, M.D. Reddy, Veeram Reddy Surendranath Professor Assistant Clinical expertise: Research expertise: Education: 2004 M.D., Indies, West Grenada, Medicine, training: Post-doctoral disease Research expertise: Poonam Punjwani Thankavel, M.D. Thankavel, Punjwani Poonam Instructor Clinical expertise: international medicine international Research expertise: Tejas K. M.D. Shah, Tejas Professor Assistant Clinical expertise: Education: training: Post-doctoral Fellow, 2006-2009; Cardiology, Pediatric Fellow, 2001-2005; UT Southwestern, Pediatrics, 2009-2010 Transplantation, Heart and Failure Heart 1979; UT Southwestern, M.D., 1983 M.D., 1979; UT Southwestern, training: Post-doctoral MN, Fellow, Rochester, Foundation, Mayo Clinic and 1983-1986; Mayo Pediatrics, Resident, Hospital, Children’s Texas and Medicine of College 1986-1989; Baylor Cardiology, Pediatric 1997 Catheterization, Interventional Fellow, Houston, Cardiology 38 3rd Year 4th Year JuneCompleted 2010 Post-doctoral Fellows Cardiac electrophysiology Interests: Research Jason Imundo, M.D. patients Rejection inpediatriccardiac transplant Interests: Research Adrian Dyer, M.D. Interventional cardiology Interests: Research Frederic D.O. Bernstein, Heart Transplantation Interests: Research UT Assistant Professor, Pediatric Cardiology, Southwestern Current Position: Tejas Shah, M.D. of Genetics cardiovascular disease Interests: Research Private practice, TX Dallas, Current Position: Richards, M.D.Ashleigh Interventional cardiology Interests: Research UT Assistant Professor, Pediatric Cardiology, Southwestern Current Position: Suren Reddy, M.D. infants Patent ductus inpreterm arteriosus Interests: Research Southwestern Instructor, Pediatric Cardiology, UT Current Position: Poonam Punjwani, M.D. 1st Year 2nd Year We offer fellows qualified 4 heart transplantation heart electrophysiology imaging interventional cardiology cardiac critical care training programs in: programs training Biodegradable PDA stents Interests: Research Holly M.D. DeSena, Carbon-13 Evaluation of cardiac metabolism using NMR Interests: Research Greg Barker, M.D. ventricle systemic shunts pulmonary insingle patients treated with low aspirin after dose Aspirin resistance (pharmacodynamic) Interests: Research Arshid Mir, M.D. Cholesterol Interests: Research Preetha M.D. Balakrishnan, Cardiac critical care Interests: Research Jeremy Affolter, M.D. th -year -year Cardiology 39 velopment, but a clear understanding but the of mechanismsvelopment, is Additionally, telemedicine capabilitiesAdditionally, transmission for and review echocardiographic of and electrocardiographic studies ECGs and 549 100 ECHOs institutionsare Approximately available multiple across the to state, from Amarillo Tyler. to these from interpreted institutions.were Diagnostic services included 878 cardiac catheterizations, most involving interventional procedures. studies imaging including of Noninvasive catheter are procedures ablation. comprised and electrophysiologic those Eighty-three were of transthoracic628 transesophageal ECHOs, electrocardiographic studies7,141 studies.and 400fetal The performeddivision 226 pacemaker monitors, analyses, Holter electrocardiograms 142 852 AdditionalECHOs. studies 11,802 included (ECGs), cardiac testsMRIs. andexercise 133 Nearly 9,900 patients were evaluated inoverall the cardiac evaluation, specialty clinics outpatient focused with patients care provided for devices, implanted arrhythmia, obesity, clinics at Children’s disorders, main heart and lipid cholesterol transplantation, Marfan syndrome and campus adults with congenital heart disease. and Legacy facilities. In addition to Clinical Activities Pediatric Cardiology faculty provided more than 8,000 inpatient, outpatient and diagnostic servicescardiac in disease Inpatients care 2010. received in the 20-bed unit. CVICU care with for and Last telemetry/step-down was a 22-bed provided year, 500 surgical cases, cardiac open patients, including 359 transplants 16 and 2,395 medical with patients an length average of days in 12 the of stay CVICU and six the days on cardiology unit. inpatient Ongoing areas research of interest studies epidemiologic include congenital of heart disease, particularly within the natural Texas, state of history ductus studies patent arteriosus of in MRI neonates, preterm evaluation pulmonary of hypertension tetralogy postoperative and for Fallot, of evaluation renal of function with heart catheterization, markers cardiacfor transplant rejection, and in innovations cardiac noninvasive monitoring. Collaborative studies within evaluate the to department stroke, migraine, Pediatrics protocols of include and sickle cell of diseasecomplications and childhood cancer. The cardiology division participates inmultiple multicenter trials. In interventional catheterization,assessing various devices, including coarctation the of including and Amplatzer occluders, management and Helex current trials are trial multicenter that is anticipated a recently completed athletic It stents. of of the screening placement processes will are contributing national quality a to evaluation. broader a be used for We initiative assess to the care with patients of hypoplasticheart left multicenter effort syndrome. A is alsounderway to evaluateventricular theof use assist devices in the pediatric population. Clinical Sciences Basic Science Basic use in for the stents cardiovascular biodegradable of An exciting is the area investigation system. new of development researchCurrent is directed an at evaluation the of tissue these to response materials in animals. Cardiopulmonary bypass is known to have adverse effects on neurologic de Members of the advance to of the division projects care areMembers children in engaged of multiple with heart disease. Research Activities Research Clinical Staff Research Surgery Research Senior Scientist, CardioThoracic Welch, Tre lacking. bypass, of model a mouse Using investigation Another is underway new injury. evaluate to of biomarkers area investigation optimize to is of cardiovascular pediatric support therapy for with patients stage end heart failure. Currently the only ventricular assist devices available are require investigating surgical an We animal placement. the feasibility for model a catheter of device. delivered additional One animal research area is the optimization of fetaltechnologies for intervention. Cardiology 40 t 1PPOBN1VOKXBOJćBOLBWFM .% t $MBVEJP3BNBDJPUUJ .% t "MBO/VHFOU .##4 '3"$1 t -ZOO.BIPOZ .% t t t .BUUIFX-FNMFS .% t t t "NZ-+VSBT[FL .% t t $BUIFSJOF*LFNCB .% t $BOEBDF(JCCJO .% t %BWJE&'JYMFS .% t t t .JDIBFM%BZ .% t t 4IBOOPO&#MBMPDL .% t t "MJFTTB1#BSOFT .% Presentations/Teaching Activities Pediatrics, San Francisco, 2010 CA,October Weeks of Gestation,” American Academy of Pediatrics National Conference and Exhibition, on Perinatal Section “Echocardiographic Prediction of Spontaneous Closure Pediatrics, San Francisco, 2010 CA,October Weeks of Gestation,” American Academy of Pediatrics National Conference and Exhibition, on Perinatal Section “Echocardiographic Prediction of Spontaneous Closure Cardiomyopathy,” Annual 59th Session,CollegeCardiology, Scientific American Atlanta, GA, March 2010 Cardiomyopathy Presenting Results During fr Childhood: Population-based Study Cardiomyopathy” of Childhood and “Long-term Outcomes of Hypertrophic “Long-term Outcomes of Dilated Cardiomyopathy Presenting Results During from Childhood: aNational Healthy Pediatric Population,” American Academy of Pediatrics, San Francisco, 2010 CA,October “Quality of Life Scores inChildren and Adolescents with Congenital are Heart Disease Lower than inthe of Echocardiography,Society San Diego, CA,June 2010 “Coarctation of Aorta: the IdentificationLate Complications,”of 21stAnnualScientific Sessions, American AnnualSessions, ScientificSociety of Echocardiography, American San Diego, CA, June 2010 RepairedCongenital “The Chair: Session Patient forthe Non-expert: What Problems Should IAnticipate,” 21st Pediatric Cancer,” 23rd Annual Meeting, of Pediatric American Society Hematology Oncology, April 2010 “Evaluation of Late Cardiotoxicity inChildren Who Received Anthracyclines Low for Dose Treatment of Abstract American Heart Session, Associatio “Mortality of 216Autopsy inHLHS:Review of Aortic Cases Atresia with Attention to Coronary Pathology,” Oral Switzerland, September 2010 Invited speaker, Annual 24th Meeting of European the Association for Cardiothoracic Surgery, Geneva, Anatomy“The Congenitally of Corrected Transposition” and “AnatomicalConsiderations in Ebstein’s Anomaly,” Echocardiography Conference, Atlanta, GA,April 2010 “Small Group Demonstrations of Congenital Pathology,” Heart Disease Invited speaker,16th Annual Pediatric “Infective Endocarditis,” Pediatric Residents, Children’s Medical Center September Dallas, 2010 “Cardiac Development,” for Seminar Embryology First Year Medical Students, UTSouthwestern, March 2010 Director: AdvancesCourse inFetal Echo, Children’s Medical Center, September 2010 Symposium, Austin, 2010 October “Mortality First inthe Five Years of Life inInfants with Single Ventricle,” Texas Research Defects Birth Hospital, UTHealth Center, Science Tyler, 2010 October TX, “Pre-sports Screening and Sudden Death inYoung Athletes,” Pediatric Grand Rounds, Trinity Mother Frances Medical Center at Legacy, June 2010 “Prenatal Diagnosisof Hypoplastic Left Heart Syndro Center, April 2010 “Tachyarrythmias: What To with Do Fast Heart Rates,” EmergencyMedicine Conference, Children’s Medical Medical Center at Legacy, September 2010 “Fetal Right and Lesions,” Left Obstructive Heart Conference:Statewide Advances in ECHO,Fetal Children’s Hospital, UTHealth Center, Science Tyler, July TX, 2010 “Commonly inCongenital Missed Diagnoses Heart Disease,” Pediatric Grand Rounds, Trinity Mother Francis Presentation) in Pediatric Cardiac Transplant Recipients,” American “Use of Highly Sensitive Troponin Tand N-Terminal Pro-Brain Natriuretic Peptide to Acute Diagnose Rejection Heart AssociationSessions, Scientific Chicago, IL, November 2010 “Feasibility and Utility of Pre-participation Cardio n Scientific Sessions,n Scientific Chicago, IL, November 2010 vascular Screening inaState-Fundedvascular Program,” American me,” Maternal Fetal Medicine Conference, Children’s Heart Association, Chicago, IL,November 2010(Poster of the Ductus Arteriosus inNeonatesof Ductus Arteriosus the Than 30 Less inNeonatesof Ductus Arteriosus the Than 30 Less om aNational Population-b ased Study of Childhood Cardiology 41 vascular Screening in a State-Funded Program,” American American Program,” vascular in a State-Funded Screening CTSNet Congenital Portal Congenital CTSNet Surgery Heart & Congenital Pediatric for Journal World Pediatric Cardiology Pediatric Pediatric Cardiology Pediatric Pediatric Cardiology Pediatric ” Long Term Follow Up of the First Generation Amplatzer Duct Occluder (Phase I and Phase II Trials) is is Phase (Phase Duct Trials) II I and Occluder Amplatzer Generation the First of Up Follow Term ” Long (PICS-AICS), Symposium Cardiac Interventional Adult and Pediatric Rates,” Closure Excellent with Associated Presentation) 2010 (Poster July IL, Chicago, Cardio Pre-participation of Utility and ”Feasibility 2010 November IL, Chicago, Scientific Sessions, Association Heart Society Rhythm Scientific Annual Heart Disease,” Heart Congenital and in Pediatrics Device Issues ”Implantable 2010 May CO, Denver, Sessions, Director, Cardiac Imaging Cardiac Director, Society American Echocardiography of Committee, Ethics Member, Member, Grand Rounds Committee, Department of Pediatrics, UT Southwestern Pediatrics, of Department Committee, Rounds Grand Member, Laboratory Catheterization Cardiac Director, Cardiology Interventional Director, Program Training Board Advisory Leadership Center Heart Member, Director, Echocardiography Laboratory Echocardiography Director, Reviewer, Committee Steering Network Heart Pediatric Chair, Circulation Association, Heart American Board, Editorial Association Heart American Reviewer, Abstract UT Southwestern Cardiology Fellowship, Pediatric Director, Director, Heart Center Education Center Heart Director, Congenital and Pediatric International Group, Working Archiving and Group Working Nomenclature Member, CodeCardiac Member, Board Editorial Member, Board Editorial Director, Cardiac Outreach Cardiac Director, Reviewer, UT Southwestern Committee, Monitoring and Oversight Cardiology Scholarship Pediatric Chair, Children’s Center, Heart Medicine, Fetal Director, Physician Consultant with the Epic Build Team for Templates, Children’s Templates, for Team Build the Epic with Consultant Physician Imaging Resonance Magnetic Cardiac Director, Clinic Cardiology Preventive Director, Director, Division of Pediatric Cardiology Pediatric of Division Director, Children’s Center, Heart Co-director, Children’s Electrophysiology, Cardiac Pediatric Director, Editor, Associate Program Transplant Heart Director, Medical UT Southwestern Reviewer, Entrance $MBVEJP3BNBDJPUUJ .% "MBO8/VHFOU .##4 '3"$1 -ZOO.BIPOZ .% .BUUIFX4-FNMFS .% "NZ-+VSBT[FL .% $BUIFSJOF.*LFNCB .% .JDIBFM%%BZ .% 77JWJBO%JNBT .% 4IBOOPO&#MBMPDL .% 4BSBI%#MVNFOTDIFJO .% "MJFTTB1#BSOFT .% 8JMMJBN"4DPUU .% .4 Major Administrative or Leadership Responsibilities Major Administrative
*MBOB;FMUTFS .% t t ćPNBT;FMMFST .% t Cardiology 42 ćPNBT;FMMFST .% 1PPOBN1VOKXBOJćBOLBWFM .% $MBVEJP3BNBDJPUUJ .% "MBO/VHFOU .% -ZOO.BIPOZ .% .BUUIFX-FNMFS .% %BWJE'JYMFS .% .JDIBFM%BZ .% 4BSBI#MVNFOTDIFJO .% 8JMMJBN4DPUU .% .4 /AwardsHonors ćPNBT.;FMMFST .% Texas Super Doctors, PediatricianBest inDallas, PosterBest Presentation, First Annual Fellows’ Senior Research Day, Department of Pediatrics, UTSouthwestern National Conference and Exhibition, American Academy of Pediatrics Young Investigator Travel Award, 2010 Texas Super Doctors, PediatricianBest inDallas, PediatricianBest inDallas, Texas Super Doctors, PediatricianBest inDallas, Texas Super Doctors, inAmerica Doctors Best PediatricianBest inDallas, PediatricianBest inDallas, Texas Super Doctors, PediatricianBest inDallas, PediatricianBest inDallas, Texas Super Doctors, inAmerica Doctors Best Reviewer, Reviewer, Abstract reviewer, PICS Scientific Meeting Abstract reviewer, SCAIScientific Meeting Physician Chair, EPIC Portal Committee Chair,Committee, Scientific CCISC Physician Director, Continuing Medical Education Department, Children’s President, Congenital Cardiovascular Interventional Study Consortium Children’s (CCISC), Vice President, Medical Children’s StaffService, Pediatric Infectious Disease Pediatric Cardiology Texas Monthly Texas Monthly Texas Monthly Texas Monthly Texas Monthly Texas Monthly D Magazine D Magazine D Magazine D Magazine D Magazine D Magazine D Magazine D Magazine
“Echocardiographic Prediction of Spontaneous Closure of the Ductus ofthe Closure ofSpontaneous Prediction “Echocardiographic Arteriosus in Neonates Less than 30 Weeks Gestational Age” Gestational Weeks 30 than Less Neonates in Arteriosus 1st Annual Senior Fellows Research Day 1st Fellows Research Annual Senior Dr. Poonam Thankavel Punjwani Best Poster AwardBest atthe Critical Care Medicine 43 , 1994; University of Louisville School Louisville of , 1994; University cum laude cum Leticia Castillo, M.D., Professor, Thomas Fariss Marsh, Jr. Chair in Pediatrics Pediatrics in Chair Jr. Marsh, Fariss Thomas Professor, M.D., Leticia Castillo, her began Medicine Care Critical Pedicatric of the Division of Director and she where de Mexico, Autonoma Nacional the Universidad at medical career residency in pediatrics in Mexico and her internship Following her M.D. received Center, Medical England the New at resident and served she intern as an City, Critical in Pediatric a fellowship then completed She Boston, Massachusetts. a postdoctoral fellowship and General Hospital Massachusetts at Medicine Care Castillo Dr. Technology. of Institute Biochemistry Massachusetts at in Nutrition the laboratory at School as a scientist Medical Harvard served at the faculty on 2005 she served In Technology. of Institute Massachustetts Nutrition, Human of the at investigator as a senior and Medicine of College Baylor at the faculty on served has She as a permanent USDA. Center, Research Nutrition Children’s at the Review Scientific Group Trauma Anesthesia and the Surgery, at member Center the National for Board the Advisory on and Health of Institutes National Child of Institute National Shriver the Eunice at Research Rehabilitation for of area the on contributed has Castillo NIH. Dr. the of Development Health illness. critical acid metabolism during amino and resistance insulin Critical Medicine Care University of Tennessee at Memphis, Resident, Pediatrics, 1998-2001; Pediatrics, Resident, Memphis, at Tennessee of University University of Nebraska, Lincoln, Fellow, Protein Biochemistry, 1995-1997 Biochemistry, Protein Fellow, Lincoln, Nebraska, of University Effects of low dose ketamine infusion, safety of Lorazepam use in critically use critically in of Lorazepam safety infusion, ketamine dose low of Effects Surgery, cardiac function following burn injury and sepsis, matrix and injury burn following function cardiac Surgery, Pain control, sedation control, Pain University of Louisville, KY, B.A., B.A., KY, Louisville, of University State University of New York at Fredonia, B.S., 1989; State University of New York at at York New of University 1989; State B.S., Fredonia, at York New of University State Leticia Castillo, M.D. Leticia Castillo, Director, Pediatric Critical Care Medicine Pediatric Director, Deborah L. Carlson, Ph.D. L. Carlson, Deborah Surgery and Pediatrics Professor, Assistant Research expertise: ill children Education: distinction, 2008 M.S.C.S., with UT Southwestern, 1998, M.D., KY, Medicine, of training: Post-doctoral 2001-2004 Medicine, Care Critical Pediatric Fellow, UT Southwestern, dysfunction in cardiac metalloproteinases Education: 1996 Biology, and Cellular Molecular Ph.D., Division, Park Roswell Buffalo, training: Post-doctoral Cindy Darnell Bowens, M.D., M.S.C.S. M.D., Cindy Darnell Bowens, Professor Assistant Clinical expertise: Research expertise: Faculty The The cardiovascular care unit,intensive a tertiary facilitylevel congenitalheart with complex disease, expandedits faculty Recruitment additional attendings seven of to faculty and grow. to continues in continues an effortmeet to the growing demands and patients of referring in physicians the area. In 2010 the CriticalIn Care 2010 Division extended the to Legacy Nkwantabisa Raymond campus, Dr. serves where as Clinical Medical at Legacy Center serving Children’s at This unit six-bed Director. north the Dallas pediatric community is the only pediatric care intensive unit in the area. The division’s internationallyrecognized The division’s criticalprogram, of fellowship care largest one the competitive most and programs, attracts and medical pediatric residents fellows, top of graduates. students takes Teaching the at place bedside and during lectures and simulation sessions. In addition, there is an array research of training opportunities learnand fellows ask to physiologic andrelating answer cellular, helping questions scientific to genetic,molecular, the nutritionaland aspects metabolic pediatric of critical care medicine. The DivisionPediatric of Critical Care Medicine plays a vital role in providing care to critically making and and the ensure to the care innovations is continuously is of patient provided Children’s improvements ill children at highest has a long-standing history quality. It clinical, of and translational bench research. Critical Care Medicine 44 Care and Resuscitation Research, 2003-2005 2004; Safar Center for Resuscitation Research, Pittsburgh, PA, NRSAFellow, Neurointensive 2001; Children’s Hospital of Pittsburgh, PA, Fellow, Pediatric Critical Care Medicine, 2001- Post-doctoral training: M.D., 1998 Education: Research expertise: Research expertise: Clinical Assistant Professor Mandeep Chadha,M.D. 2005-2008 Resident, Pediatrics, 2004-2005;UT Southwestern, Fellow, Pediatric Critical Care Medicine, Post-doctoral training: Medicine, Wichita, M.D., 2001 Education: investigation and improvement of intensive care neurologic monitoring expertise: Research expertise: Clinical Assistant Professor Joshua Koch, M.D. 1996-1999; Fellow, Developmental Neurobiology, 1997-1999 Resident, Pediatrics, 1995-1996;UTSouthwestern, Fellow, Pediatric Critical Care Medicine, Post-doctoral training: Medicine, Seattle, M.D., 1992 Education: injury-induced neurogenesis brain inthe expertise: Research expertise: Clinical Associate Professor, Pediatrics and Developmental Biology Steven Kernie, M.D. Medicine, 2007-2010 Pediatrics, 2004-2007;Children’s Hospital, MA,Fellow, Boston, Pediatric Critical Care Post-doctoral training: M.D., 2004 Education: expertise: Research expertise: Clinical Assistant Professor Green,Michael M.D. Pediatrics, 1997-1999;UTSouthwestern, Fellow, Pediatric Critical Care Medicine, 2000-2003 Post-doctoral training: Southwestern, M.D., 1996 Education: expertise: Research expertise: Clinical Assistant Professor Leslie Garner, M.D. Fellow, Pediatric Critical Care Medicine, 2002-2003and 2005-2008 Resident, Pediatrics, 1999-2002;University of Tennessee Health Center, Science Memphis, Resident, Pediatrics, 1993-1995;University of Oklahoma Health Center, Science Tulsa, Post-doctoral training: Education: failure expertise: Research in continuous renal replacement therapies expertise: Clinical Assistant Professor Archana Dhar, M.D. University of Tulsa, OK, B.S., Stanford University, Stanford, CA,B.A., 1988;University of Washington of School Baylor University, Waco, B.A., 2000;UTHealth TX, Center at Science San Antonio, Trinity University, San Antonio, B.S., 1997;University TX, of Kansas of School Vanderbilt University, Nashville, TN,B.A., B.J. Medical College, Gujarat University, India, M.B.B.S., 1993 Neurocritical care Pediatric critical care Pediatric critical care; of use online, noninvasive, intravascular monitoring Ischemic brain injury, traumatic brain injury Pediatric critical care, pediatriccardiac critical care Pediatric critical care Traumatic brain injury Neurocognitive outcomes inchildren after congenital surgery, heart Hippocampal development, neuralstem cellsintraumatic brain injury, Pediatric acute lung injury, simulation Macrophage function Effects of CVVH and ICP monitoring on outcomes following acute liver Vanderbilt University Medical Center, Nashville, TN,Resident, Arkansas Children’s Hospital, Little Resident, Rock, Pediatrics, 1998- UT Southwestern/Children’s, Resident, Pediatrics, 2001-2004; Chief UT Southwestern/Children’s, Resident, Pediatrics, 1992-1995;Chief UT Southwestern/Children’s, Intern, Pediatrics, 1996-1997;Resident, Gujarat University/Civil Hospital, Ahmedabad, Gujarat, India, cum laude , 1994;UTMedical Branch at Galveston, summa cum laude , 1992;UT Critical Care Medicine 45 , 1996 cum laude cum University of California San Francisco, Resident, Pediatrics, 1997-2000; Pediatrics, Resident, Francisco, San California of University GA, Resident, Atlanta, Medicine, School of Emory University University of Kentucky, Lexington, Resident, Pediatrics, 1978-1981; Pediatrics, Resident, Lexington, Kentucky, of University 1999- Pediatrics, FL, Resident, Miami, Hospital, Schneider Children’s Brookdale University Hospital and Medical Center, Brooklyn, NY, NY, Brooklyn, Center, Medical and Hospital University Brookdale SUNY Health Center, Syracuse, Resident, Pediatrics, 1987-1990; Children’s Children’s 1987-1990; Pediatrics, Resident, Syracuse, Center, Health SUNY Pulmonary outcomes in neuromuscular disease, trials in pediatric clinical in neuromuscular Pulmonary outcomes technology of in medical role and usebypass, cardiopulmonary of Effects MRI imaging biomarkers of neuronal injury, neural stem cells neural stem injury, neuronal of biomarkers MRI imaging simulation Medical Quality improvement, patient safety patient improvement, Quality Traumatic brain injury, neural protection strategies neural protection injury, brain Traumatic sedation transport, medicine, care critical Pediatric Pulmonary ventilation, congenital heart disease, single ventricle physiology, heart physiology, disease, ventricle single congenital Pulmonary ventilation, Acute lung injury, mechanical ventilation mechanical injury, lung Acute Pediatric critical care critical Pediatric General and cardiac ICU care ICU cardiac General and San Jose State University, CA, B.S., 1993; University of California San Francisco Francisco San California of 1993; University CA, B.S., University, State Jose San University of Kentucky, Lexington, B.G.S., 1975; University of Kentucky College of College of Kentucky of 1975; University B.G.S., Lexington, Kentucky, of University DC, Washington, University, 1994; Georgetown A.B., PA, Easton, College, Lafayette Wellesley College, MA, B.A., 1983; New York Medical College, Valhalla, M.D., 1987; M.D., Valhalla, College, Medical York New 1983; B.A., MA, College, Wellesley University Medical School of Pecs, Hungary, M.D., M.D., Hungary, Pecs, School of Medical University Louisiana Tech University, Ruston, B.S., 1999; Louisiana State University Health Health University State 1999; Louisiana B.S., Ruston, University, Tech Louisiana Education: Assistant Professor Assistant Legacy at Children’s Unit, Care Intensive Pediatric Clinical Director, Clinical expertise: Raymond Nkwantabisa, M.D. Nkwantabisa, Raymond Assistant Professor Assistant Clinical expertise: Susan Morris, M.D. Susan Morris, Research expertise: Education: 1997 M.D., School Medicine, of training: Post-doctoral 2002-2005 Medicine, Care Critical Pediatric Fellow, UT Southwestern, Research expertise: Education: 2003 M.D., Shreveport, Sciences Center, training: Post-doctoral Atlanta of Healthcare Medicine/Children’s School of 2003-2006; Emory University Pediatrics, 2006-2009 Medicine, Care Critical Pediatric Fellow, Egleston, at Assistant Professor Assistant Clinical expertise: Darryl M.D. Miles, extracorporeal support extracorporeal Research expertise: T. Raju Meyappan, M.D. Raju Meyappan, T. Professor Assistant Clinical expertise: critical care critical Education: 1978 M.D., Lexington, Medicine, training: Post-doctoral practice Education: 1999 M.D., Brooklyn, Medicine, of College Center Medical Downstate M.S., 1995; SUNY training: Post-doctoral Peter M. Luckett, M.D. M. Luckett, Peter Professor Clinical expertise: Research expertise: Pediatric Fellow, NY, York, New Surgeons, and Physicians of College University Columbia 1984-1987 Physiology, Cellular 1981-1984; Fellow, Pulmonary Medicine, Critical Cardiac Pediatric 2002-2005; Fellow, Medicine, Care Critical Pediatric 2002; Fellow, 2005-2006 Care, Fiona H. Levy, M.D. H. Levy, Fiona Professor Children’s Quality, of President Vice Clinical expertise: Research expertise: Education: 2001 M.B.A., MO, Louis, St. University, Washington training: Post-doctoral 1990-1993 Medicine, Care Critical Pediatric Fellow, WA, Seattle, Center, Medical and Hospital Post-doctoral training: training: Post-doctoral Reserve 2002-2003; Case Western Pediatrics, 2000-2002; Chief Resident, Pediatrics, Resident, Critical Pediatric Fellow, OH, Cleveland, Hospital, & Children’s Babies University/Rainbow 2003-2006 Medicine, Care Critical Care Medicine 46 1982-1984, Associate 1984-1985 1981-1984; Cardiovascular Research Institute, University of California San Francisco, Fellow, 1978-1981; University of California San Francisco, Fellow, Pediatric Critical Care Medicine, Post-doctoral training: Education: inflammation Research expertise: Research expertise: Clinical Joel B. Steinberg, M.D. Chair inPediatrics Professor, Vice Chairman Julio Pérez Fontán, M.D. UT Southwestern, Fellow, Pediatric Critical Care Medicine, 1992-1995 Post-doctoral training: of Medicine, CA,M.D., with research honors, 1989 Education: autoimmunity, innate immunity and myocardial dysfunction expertise: Research expertise: Clinical Associate Professor, Pediatrics and Molecular Biology M.D.James Thomas, Children’s Hospital, OH, Fellow, Pediatric Critical Care/Clinical and Research, 1999-2002 Clinic Foundation, OH, Resident, Pediatric and Adolescent Medicine, 1996-1999;Cincinnati National Maternity Hospital, Dublin, Ireland, Resident, Neonatology, 1995;TheCleveland 1993-1994; TheChildren’s Hospital, Dublin, Ireland, Resident, Pediatrics, 1994-1995;The Post-doctoral training: Child Health, 1995 Education: safety and quality expertise: Clinical Associate Professor Maeve Sheehan,M.D. Children’s Hospital of Pittsburgh, PA, Pediatric Critical Care Fellowship, 1990-1993 Post-doctoral training: Medical Kansas School, City, 1987 Education: activating polypeptide II,51integrin /FNVEGFRinteractions, pancreatic tumor growth expertise: Research expertise: Clinical Associate Professor Margaret Schwarz, M.D. Minnesota, Minneapolis, Fellow, Pediatric Critical Care, 2001-2004 Center, Brooklyn, Resident, Pediatrics, 1997-2000;ChiefResident, 2000-2001; University of Royal College of Physicians, London, MRCP, Pediatrics, 1994; SUNY Downstate Medical Post-doctoral training: Education: injury expertise: Research expertise: Clinical Assistant Professor M.D.Lakshmi Raman, Pediatric Nephrology, 2008-2010 University at Buffalo, NY, Fellow, Care,Pediatric Critical Southwestern, 2002-2005;UT Fellow, Post-doctoral training: Brooklyn Hospital Center, NY, Resident, Pediatrics, 1997-2000; Education: Bangalore Medical College, India, M.B.B.S., 1996 children children requiring CRRT, effects and optimal management of fluid criticallyoverload in ill Early identificationResearch expertise: of and factors affecting outcomescritically in ill Critical care nephrology,Clinical expertise: continuous renal replacement therapies Instructor Vinai ModiniModem,M.D. University Santiago De Compostela, De Spain, M.D., 1977 University of Dublin, College School Medicine, Ireland, M.D., 1993;Diploma in Madras Medical College, University of Madras, India, M.B.B.S., 1989 Princeton University, NJ, A.B., University of Missouri, Kansas City, 1986,B.A., University of Missouri Six-Year Pediatric critical care Pediatric critical, pediatric cardiac critical care Pediatric critical care, immunology Multi-system organ failure, stabilization, pediatric triage and transport, Pediatric and cardiac critical care Airway smooth muscle, smooth Airway autonomic system, neurogenic nervous Pulmonary morphogenesis Pulmonary and vasc Chronic hypoxia and hippocampal injury, hypothermia in traumatic brain Innate immune response to infection, innate immune signaling and Universidad Autonoma deBarcelona, Spain, Resident, Pediatrics, Children’s Hospital of Angeles, Los CA, Resident, Pediatrics 1989-1992; Royal College of Physicians, London, Diploma inChildHealth, 1993; St. Vincent’s Hospital, Dublin, Ireland, Resident, Medicine and Surgery, Children’s Hospital, Columbus, OH, Resident, Pediatrics, 1987-1990; magna cum laude ularization, endothelial-monocyte , 1981;Stanford University School Critical Care Medicine 47 Christopher S. Todd, M.D. S. Todd, Christopher Position: Current Health Tech Texas Professor, Assistant Amarillo Science Center, Research Interests: role Pulmonary vascular development; signaling EMAP II in integrin of Anne Mahan, M.D. Anne Mahan, Research Interests: in pneumocyte alpha-5-beta-1 of Role differentiation Kyle Lieppman, M.D. Lieppman, Kyle Research Interests: after neurogenesis Hippocampal injury brain traumatic tegies to prevent shunt thrombosis in the single thrombosis shunt prevent to tegies Harbor UCLA Medical Center, Torrance, CA, Resident, Pediatrics, Pediatrics, Resident, CA, Torrance, Center, UCLA Medical Harbor Extracorporreal membrane oxygenation, pediatric trauma oxygenation, membrane Extracorporreal Ashraf M. Resheidat, M.D. M. Resheidat, Ashraf Position: Current UT Anesthesia Resident, Southwestern Research Interests: injury acid in hyaluronic to responses Immune lung Patrick Hairston, M.D. Hairston, Patrick Research Interests: on glial hypoxia chronic of Effect development M.D. Hume, Janet Research Interests: inflammatory function and Myocardial MRSA in community-acquired response 8 caspases 1, 3, and of sepsis-role University of California at Los Angeles, B.S., 1983; University of Illinois College of of College Illinois of 1983; University B.S., Los Angeles, at California of University Completed June 2010 Completed June Post-doctoral Fellows Fellows Post-doctoral Maria Teresa Zuluaga, M.D. Zuluaga, Teresa Maria Professor Assistant global injury, heart disease, brain congenital medicine, care critical Clinical expertise: Pediatric health expertise: injury Research Brain 1994 M.D., Colombia, CES, Medellin, Universidad Education: Resident, Juan, San Puerto Medicine, Rico School of of University training: Post-doctoral Center/Children’s Medical Francisco San California of University 2002-2005; Pediatrics, 2005-2008 Care, Critical Pediatric Oakland, Fellow, Center, Research and Hospital Joshua Wolovits, M.D. Joshua Wolovits, Professor Assistant in the ICU initiatives quality-care Clinical expertise: care, critical Cardiac heart disease, in congenital expertise: neuro-protection Research and hemodynamics Cerebral stra patient, cardiac in the strategies sedation Marita T. Thompson, Thompson, M.D. T. Marita Professor Associate Clinical expertise: Education: 1989 M.D., Chicago, Medicine, training: Post-doctoral 1993-1996 Medicine, Care Critical Pediatric Fellow, UT Southwestern, 1989-1992; patient ventricle 2002 M.D., 1998; UT Southwestern, B.A., UT Austin, Education: 2002-2003; Resident, Pediatrics, Intern, UT Southwestern/Children’s, training: Post-doctoral 2005-2008; Care, Critical Fellow, Francisco, San California of University 2003-2005; Pediatrics, 2008-2009 Medicine, Care Critical Cardiac Fellow, UT Southwestern, 3rd Year 3rd Critical Care Medicine 48 t t t t Dr. Steve Kernie’s Lab t t t Dr. Carlson’s Deborah Lab t t Dr. Castillo’s Leticia Lab Research Staff 1st Year 2nd Year Shereen Mohideen, Co-mentor Mohideen, Shereen Kyle Lieppman, M.D., Post-doctoral Researcher Wei Ph.D., M.A., Li, Post-doctoral Researcher Student Graduate Gilley, B.S., Jennifer Hume,Janet M.D., Ph.D., Post-doctoral Trainee Clinician Jeong Hue, Sim Ph.D., Post-doctoral Researcher Jeremy Affolter,M.D., Post-doctoral Researcher M.D., Post-Doctoral Researcher Manzuri, Shai Coordinator Study Research M.H.A./M.B.A., B.S., Abbas, Munira obese obese Aminoacidand lipid in metabolism subjects Interests: Research M.D. Borke, Kimberly seconds using inpediatrics CPAP of 40over 40 Lung recruitment maneuver Interests: Research Manish M.D. Bajracharya, critical underconditions of inflammation and illness Regulation of nutrient homeostasis Interests: Research Shai Manzuri, M.D. disruption inToll/IL-1 signaling IRAK-1and IRAK-2deletions and its Interests: Research Humberto Liriano-Fanduiz, M.D. cellsto cause thrombosis antibodiy interaction with endothelial Mechanisms of antiphospholipid Interests: Research Lanier,Lane M.D. Initial lumen formation invasculogenesis Interests: Research Hariprem Rajasekhar, M.D. fibrillogenesis acuteafter lung injury Role of alpha 5integrin inlung repair/ Interests: Research Persad,Elizabeth M.D. thermal injury complicated thermal by sepsis inresponse and injury to thermal and heart abundance their and activity Identify and characterize NLRsinthe Interests: Research Kamna Jaiswal, M.D. feedings during sepsis dysyncrhony Clock with continuous Interests: Research Eugene Chung, M.D. Critical Care Medicine 49 ive careive unit with seasonal influenza influenzanovel versus Amino acid homeostasis and utilization during enteral or parenteral routes of administration provided to to provided administration of routes parenteral or enteral during utilization and homeostasis acid Amino children. ill critically Parenteral and enteral sulfur amino requirements acid maintain to methylation function and glutathione rates. synthesis andProtein energy inflammation interactions of under conditions and insulinresistance. of The current impact critical practicescare providingfeedings light continuous on and circadian mechanisms clock and insulin resistance in critically ill mass children. this spectrometric For and purpose, use isotopic stable we techniques. imagining Michelle Jennings, Research Assistant II Research Senior Scientist Lin, Ph.D., Ken-Meng Research Senior Associate M.D., Tsen, May Munira Abbas, B.S., M.H.A./M.B.A., Research Study Coordinator Jamie Wright, ResearchJamie Intern Wright, Researcher Post-doctoral Ph.D., Yang, Cui-Ping B.S., Graduate Student Yu, Tzong-Shiue Gui Zhang, ResearchAssistant II Xiangmei M.S., Kong, Research Assistant I Researcher Post-Doctoral Maria M.D., Afanador, Researcher Katherine Bennett, Post-Doctoral M.D., ResearcherAnne Mahan, Post-Doctoral M.D., Researcher Post-Doctoral M.D., Todd, Christopher Dr. Archana an of retrospective Dhar IRB-approved is theDr. Principal study comparing (PI) the Investigator clinical characteristics children of admitted the to pediatric intens The long term goals of Dr. termLeticiagoalsfocused long laboratory Dr. definingof on Castillo’s The are regulatorythe mechanismsof inflammation of under conditions homeostasis criticaland nutrient illness, processeshow nutrient these and affect nutritional balance for requirements and function maintenance. is focused translational on Attention studies on: t t t t characterizeto is work Deborah the inflammasomeCarlson’s Dr. of over-arching theme mediatingThe the inflammatory response in heart the following thermal injury and thermal injurywith complicated is sepsis. She currently examining the mechanism activation, identifying caspase-1 of the inflammasome its components and within the heart platform a andcreate within the myocyte (NLR’s) NOD-likereceptors proposes specifically. that She regulation familyfor the of IL-1 suggesting through members in both caspase-1, a role innate and adaptive immunity the inflammasome.for is currentlywork Her determining essentialare if NLR’s mediatingin the inflammatory inresponse the heart thermal in to response injury and thermal injury with complicated sepsis, suggesting that inflammasomes are differentially expressed in heart,the responding to atier upregulation at of likewhere system functional is required assemble to least two components inflammasomes. of model This suggests tissueconcept a are project of results this heartThe of stress. to the response the into insight provide privilege,may inflammation and aimed targeting at cardiac member induced dysfunction specificmechanisms of IL-1 in heart, the and specificin cell types, such as the myocyteto after allow injury, the use in clinicalpractices of established such as estrogentherapies regulation, caspase 1 inhibition and cardiac P2X7 inhibitors more selectively to allow directed Cindy Darnell the of effectivenessDr. focuses the researchof on her cytokine delineation and mitigation andthe improvement regulation. undesirable effectsof sedative the and analgesicmedications commonly used in the of patients care in the intensive care the unit. RESRORE for is the an investigator She site NIH proticol, funded a of study the on implementation in weaning criticallysedation protocol ill children. also the She a national by Department study serves for sponsored Health of as Sub-PI and Human Services:H1N1. Surveillance Registry, in for liver is Influenza study an and involved IRB-approved “Outcomes (H1N1) titled A Novel transplantationfailure liver acute in for children, specifically The plasma exchange: of monitors, useCVVHD, ICP Dallas experience.” Research Activities Research number researchThe of and activities diversity withinFaculty members engaged are to the division continues grow. in bench, translational and clinical research projects. There aremultiple areas highlight. to of investigationproud that the division is t t t Dr. James Thomas’s Lab Thomas’s James Dr. t Dr. Margaret Schwarz’s Lab Schwarz’s Margaret Dr. t t t t Lakshmi Lab Dr. Raman’s t t t t t Critical Care Medicine 50 communicate with the cell’s interior, using signaling proteins common to all the TLRs as well as the interleukin-1 the as well as TLRs the proteins common interior, cell’s to all the signaling with using communicate These receptors insult. the responses to contain systemic and local trigger and injury invasion tissue and microbial receptors proteins toll-like detect (TLRs) –the –that of mammalian family conserved Project uncovered ahighly flies) (fruit Drosophila in fromresearch developmentGenome level.the stemming Advances and a molecular Human Dr.his workinvestigation on infection theand Thomas James of andon thefocuses how injury responds host senses to development. lung abnormal in result that processes to disease treat targets new therapeutic of development, lung to understanding leading the expand greatly will targets have that factors multi-cellular those impacted. Identifying is cells whether endpoint Their morphogenesisimmature factors. these is to identify of growth morphogenic to able this vascular-specific when change are exposed to make cells of oxygen-exchanging becoming capablearethat cells immature whether have contextthat they developed examine this models specific Within factors. growth factors have on other cell types that have typically vascular influence known that look the not at to exchange specifically Researchers cells oxygen. lung beendistal the influence determined to be responsive to vascular growth to ability their as well as types vessel beenplaced concept, individual on has focus the this order examine to better lung development. to In functional of brings contributions vasculature on the the focuses Dr. that Schwarz research The Margaret development. lung dysfunctional to contribute growth vessel in alterations formation, lung During response remodeling toacute and TBI. to elucidate brain’s techniques the neuro-imaging advanced using children, in studies for abasis future as serve will hopefully analysis outcome. relationship to neuro-cognitive This their and of injury patterns severe TBI to identify moderate to with children in findings CT and MRI analyzing and severeTBI. currently moderate Dr. is after Miles long-term how to affect developmental investigate study genetic polymorphism outcome funded children in a NIH Center (BNIC) Injury CMC Nerve investigator and isthe on site and principal member Brain a contributing of the investigation, he is from basic science to transition clinical response. remodeling the In contributeand neural to the (TBI) hypoxic-ischemic and encephalopathy injury brain traumatic suchas insults to various vulnerable selectively are progenitors glial and neuronal immature demonstrated that mouse has models injury. work transgenic His brain using outcome acquired neuro-cognitive of pediatric the development improving ultimately of novel strategies, therapeutic self-repair. neural It to and desire contribute ishis injury to the brain of traumatic mechanisms to the investigate and injury brain pathophysiology work continued the to childhood has unique his to understand Miles Dr. Darryl Dr. ispending. site isaco-investigator Luckett the PI project. children and for this ill critically in of control glucose ICUs. for application multi-center NIH alarge controlglucose pediatric An trial to adult the and in sites toinvolved naive of development, acomputer-based distribution the and validation decision supporttool for Care.”project This Critical in Research Clinical “Reengineering entitled mechanism contract Roadmap NIH of the completed Syndrome members Network Acute of Distress the (ARDSnet) acollaboration Respiratory with part as Investigators (PALISI) clinical trials group. This group Sepsis and recently Acute Injury Lung member Pediatric of the organizing initial an he was 2002 In care. critical pediatric in trials Dr. Peter Luckett’s include interests research clinical current Imaging. (NIRS) Spectroscopy Multi-Source-Detector and Head Infrared Near Ultrasound Prospective Analysis of Regional Cerebral Perfusion investigator for project, the September 1, primary 2009. He isalso Using on enrollment began and Blood Institute and Lung, Heart, the funded National by is trial (THAPCA). This Arrest Cardiac AfterPediatric Therapeutic Hypothermia trial, multi-center investigator for the Dr. site the primary Joshua as Koch serves process ofthis self-recovery. might be that enhance able to drugs investigating allow researchers to begin orfindings now lackof These oxygen. due injuries to trauma sequelaebrain following most damaging am se it depletes vital precursor cells that ultimately form ultimately that precursor cells se it depletes vital Critical Care Medicine
51 The ICU at Legacy campus offered 24/7 coverage of critically ill ill critically of coverage 24/7 offered campus Legacy at ICU The sub- chronically and supporting post-operative of all monitoring as well as children, with counts campus Raymondventilated patients, under the Dr. of leadership Legacy The Nkwantabisa. specialties. the leadership physician Sheehan, Children’s Maeve provided Dr. transport two integral program and care Access Center, patient services that differentiate critical care medicine within the regional Medical Transport Center Children’s leadership her market. Under system has an as established in a leader the reputation Dr. region. Dr. Michael Green, a Pediatric Michael Green, MA. Intensivist trained Boston, Hospital, Dr. Harvard Children’s at medical and School Teresa San the of joined Pediatric Francisco, University a Pediatric Hospital, Zuluaga, Intensivist trained M.D. Children’s at Critical Care Medical Faculty Center. Children’s at Center, provides state-of-the-art cardiovascular critical care services for children with congenital heart disease as well as as well as disease heart Clinical Activities congenital with children for services care critical was productivity a year continued of and enhanced2010 clinicalthe care Critical Division of for Care Medicine, with cardiovascular admissions remaining 3,000 The the division, year. collaboration in over for with of DivisionCardiology the Heartand the state-of-the-art provides Center, other cardiac 700cardiac additional diseases. were complex of admissionsdisease to There the Cardiovascular Intensive this for Care academic As Unit a leading critical year. of provider care services, the division measure does define not or the by ratherbut specializationthe number, or bed of carevolume success efforts of is offeredby patient andthat the quality outcomes of patients. Associate the Director of PediatricArchana Critical Dhar, Care the Program on education leadership Fellowship provided and training Pediatric the of program of Intensivists. next Marita generation ECMO The of Dr. leadershipunder the of provideMeyappam the state James to continues by Thomas supported Raju and and forart Thompson criticallycare ill Kernie, Steve faculty senior thechildren. Dr. and of leadership member Medical Under Family the Director of Perot Center Brainfor and and Nerve Injuries, standardization the division has the seen improvement of clinical practice and long-term children for with has been brainCenter instrumentalPerot follow-up injuries. The to clinicalof support the trials in the area Quality for the of division Levy, member President a senior and at Vice Fiona the Dr. of leadership Under neuroprotection. of the criticalChildren’s, care efforts division has as by refined performancewidespread participation evidenced improvement theof division faculty Cindy Darnell’s in education effortsorgan variousprocurement Dr. on projects. quality improvement the chronically lives of improve to been decisive illhave children through the awareness on and potential education organ of Susan Morris Dr. has critical taken on donation. role a leadership care through education simulation scenarios our state- at Leslie Garner Dr. exemplary hasof-the-art provided service simulation center. as the both division and residency for leader in with collaboration the Wolovitz Respiratory Joshua Department,medical Dr. rotations. during education student PICU Clinical developed Brian RRT., weaning. by headed Guidelines ventilator Walsh, for Dr. Modem Vinai Modem focusesDr. his research effortsremoval on effectof the fluid renalthrough therapy replacement in children with of patients inflammation, acute treated of a with databaseon outcome the this and development the modality. family of receptors. He has worked to genetically to family has worked He inactivate receptors. of two critical intracellular signaling – IRAK1 proteins and IRAK2 – and is studying their function in the innate of and adaptive immune including response, the development sytemic erythematosus in lupus humans and the inflammatory (SLE) acute to response infectionmurine in and in vitro models. Critical Care Medicine 52 Garner,Leslie M.D. Archana Dhar, M.D. M.D. Darnell, Cindy Ph.D. L.Carlson, Deborah M.D. Castillo, Leticia Major Administrative Responsibilities orLeadership t Joshua Koch, M.D. t M.D., Darnell, Cindy M.S.C.S. t M.D. Castillo, Leticia quality clinical care. of for high- practice the knowledge necessary foundational the develop levels all at trainees that ensures fellows for curriculum care critical weekly A projects. research of completion toward progress fellows’ of evaluation and works research of review allow Additionally, conferences research monthly division is assessed. performance divisional and practices standard of quality review cases, clinical conferences, division weekly At colleagues. therapy respiratory and nursing members, including of team participation theand education are on focused activities and teaching effort, of residents thetailored for leveltraining of sessions specifically by didactic and fellows. bedside iscomplemented This teaching opportunities. learning Critical provide hands-on major and resuscitations all interventions care practice however, rounds; platform isdaily teaching admissions, principal is based life-long the exchange habit and The to questionlearn. and on team thatintellectual foster curriculums didactic specific with and children ill of critically care the place during take students for residents, medical fellows and activities teaching Divisional Presentations/Teaching Activities t t Chair, EPIC User Critical Care Services Group, Children’s ResidentLiason, Education PICU, inthe Children’s Director,Course MSIV PICU Acute Care Rotation, Children’s Associate Director, Pediatric Critical Care Fellowship Hospital Physician Liaison for Organ Donation, Children’s Co-chair, Transplant Committee, Review Children’s Member, IACUC, UTSouthwestern Member, International Presidential Shock Society Committee for Publications Member, Presidential Shock Society Committee for Honors Nutrition, Journal of Nutrition Medicine, Pediatric Critical Care Medicine, New Englan Ad Peer hoc Reviewer, American Journal and Metabolism), of Physiology (Endocrinology Critical Care Health Ad Reviewer, hoc Integrative Nutrition and Metabolic Processes ScientificGroup, Review National Institutes of Institute Ad Reviewer, hoc ClinicalStudies and Training ScientificGroup, Review National Heart, Lung, and Blood Ad Reviewer, hoc Biomedical Imaging Technology ScientificGroup, Review National Institutes of Health Health Permanent Member, Surgery and Anesthesia Trauma (SAT) Group, Scientific Review National Institutes of Director, Pediatric Critical Care Fellowship Program Director, Pediatric Critical Care Medicine Practitioner Annual Seminar, April TX, Dallas, 2010 “Neurocognitive OutcomesCongenital After Heart Surgery,” The41st C. Kenneth Haltalin inPediatrics the for “Organ and Tissue Donation Cardiac inthe ICU,” Cardiac ICU Nurse Children’s, Lecture Series, August 2010 April “Clock and ICU Dysfunction Practices,” Pediatric Critical Care UTSouthwestern, Research Series, Seminar Nutrition, Metabolism and Obesity, UTSouthwestern, September “Insulin Resistance and Protein Metabolism inCritically “Metabolic inChildren,” Diseases Course,Chicago, Review Board August 2010
2010 d Journal of Medicine, American Journal of Clinical Ill Children,” on Obesity Alliance Series Seminar with Dr. George Lister at the department’s 1st Annual 1st Annual department’s at Dr. the Lister George with Dr. Christopher Todd discusses his research project research his ToddDr. Christopher discusses
2010 Senior Fellows Research Day, FellowsResearch Senior May 2010 Critical Care Medicine 53 ciation of Children’s Hospitals and Related Institutions Related and Hospitals Children’s of ciation (CHAPS) Council, Child Health Corporation of America of Corporation Health Child Council, (CHAPS) Core Interviewer for Intern Applicants Intern for Interviewer Core Committee BSI Center Heart Leader, Physician CA-BSI NACHRI CICU Champion, Physician Co-chair, Emergency Medicine Committee, Texas Pediatrics Society Pediatrics Texas Committee, Emergency Medicine Co-chair, Council Advisory Trauma EMS and Governor’s Committee, Pediatrics Member, Division. Care Critical Director, Quality ECMO. Director, Medical Children’s ICU, Trauma/Neurosurgical Director, Medical Review Board (IRB) Institutional Member, Ad Hoc , NHLBI Respiratory Integrative Biology and Translational Research Study Section Study Research Translational Biology and Integrative , NHLBI Respiratory Hoc Ad Services, Access and Children’s Transport Director, Medical Pediatrics of Department UT Southwestern, Mentor, Resident Children’s Project,” Lead, The Crystal“Signature Physician Ball Charity Children’s Practice, Practitioner Nurse PICU Director, Medical Executive Vice President of Medical Affairs, Children’s Affairs, Medical of President Vice Executive UT Southwestern Services Development, Program Pediatric and Dean for Associate UT Southwestern Medicine, Respiratory Pediatric of Division Director, Interim Program Grant CTSA Pilot Chairman, Radiology of Chair Committee Search Co-Chair, Grant T32 Training Director, Associate Directors Board of Children for Anesthesiologist Chairman, Core Member, ECMO Team, Children’s Team, ECMO Member, Core Children’s ICU, Clinical LeaderBSI Medical/Trauma PICU. Legacy Campus Clinical Director, UT Southwestern Pediatrics, of Department Chairman, Vice Member, American Thoracic Society (ATS) Membership Committee Membership Thoracic Society American (ATS) Member, Committee Program Assembly Pediatric ATS Member, Children’s Department, Care Respiratory Director, Medical Committee Nominating Thoracic Society American Member, Member, Council on Child Health Quality, National Asso National Quality, Child Health Council on Member, America of Corporation Child Health Committee, Leaders Steering Safety and Quality Member, Safety Patient Advancing Hospitals Children’s Member, Panel Advisory Technical Forum Quality National Member, Information Healthcare Texas with a Collaboration Group, Advisory Indicator Quality Pediatric Member, Services Health State of Department Texas Statistics, Health for the Center for Collection Committee Executive Initiative Council Data Hospital Worth Dallas/Fort Member, Hoc Ad Medical Director, Cardiovascular Intensive Care Unit, Children’s Unit, Care Intensive Cardiovascular Director, Medical Children’s CPR Committee, Co-Chair, Children’s Quality, President, Vice 2009) November (through Medicine Care Critical Pediatric of Division Director, Interim Services, Children’s Inpatient and Access of Director Ad hoc Reviewer, National Science Foundation, Faculty Early Career Development Program Development Career Early Faculty Science Foundation, National hoc Reviewer, Ad in Science Fellowship Women Epsilon/Graduate Delta Sigma Reviewer, Hoc Ad Program Research Injury Brain Traumatic Defense, of Department Reviewer, Hoc Ad Committee Advisory Clinical Research Children’s Reviewer, Hoc Ad Research Spinal Cord on Jersey New Commission The Member, Cell and MDCN-K, Neurogenesis Neuroimaging, and Neurogenetics member, NIH, NINDS, guest Member, Neurogenetics MDCN Molecular and Fate, Medical Director, Perot Family Center for Brain and Nerve Injuries Nerve and Brain for Center Family Perot Director, Medical M.D. Wolovits, Joshua M.D. Thompson, T. Marita Maeve Sheehan,M.D. M.D. Schwarz, Margaret Raymond Nkwantabisa, M.D. Raymond Nkwantabisa, M.D. Fontán, Pérez Julio T. Raju Meyappan, M.D. Meyappan, Raju T. Darryl Miles, M.D. M.D. M. Luckett, Peter M.D. H. Levy, Fiona M.D. Koch, Joshua Steven Kernie, M.D. Kernie, Steven Critical Care Medicine 54 M.D. Sheehan, Maeve M.D. Darnell, Cindy M.D. Castillo, Leticia /AwardsHonors America’s Top Pediatricians, Consumers’ Research of Council America President Medical Elect, and Dental Staff 2010,Children’s Treasurer, Medical and Dental Staff 2010 Member American Pediatric Association. Emergency Medicine 55 in North Texas Halim Hennes, M.D. Halim Hennes, Director, Pediatric Emergency Medicine Pediatric Director, SHFODZNFEJDJOFSFTJEFODZBU*OEJBOB VUIXFTUFSO UI%BMMBTBSFB .FEJDBM$FOUFS JOJDBM1SPGFTTPSBUUIF6OJWFSTJUZPG$BMJGPSOJB %JSFDUPSPG DVMUZ BU UIF FMFDUJWFSPUBUJPOTIFSF T6OJWFSTJUZ FUSBJOJOHJO SJDBJO SFTUTUIBUNBUDIUIFJST"GVMMUJNF FYQFSJFODFE JOHJOUIFFNFSHFODZEFQBSUNFOUJTPęFOTPVHIU VSOBMOBNFE FGPSFDPNJOH POOVNFSPVT E0LMBIPNB3FDPHOJ[JOHUIFPVUTUBOEJOHDMJOJDBM JTUIF%JSFDUPS QIZTJDJBOGSPN SHFODZ.FEJDBM OHBU$IJMESFOT FTMJBJTPOUPUIF FEJDBM$PMMFHFPG UJPOPGQFEJBUSJDSFTJEFOUT GBNJMZNFEJDJOFSFTJEFOUT FUSBJOJOHBOEBTTVNFESFTQPOTJCJMJUJFTJODPNQMJBODF UIFBSFBTPGQFEJBUSJD ment and education of pre-hospital pre-hospital of education and ment pediatric trauma center trauma pediatric 1 Emergency Medicine FSHFODZ.FEJDJOFEPDUPSTJO"NF only Level Level only The Faculty )BMJN)FOOFT .% .4 1SPGFTTPSPG1FEJBUSJDTBOE4VSHFSZ PG1FEJBUSJD&NFSHFODZ.FEJDJOFBU654PVUIXFTUFSOBOE.FEJDBM &NFSHFODZ4FSWJDFTBU$IJMESFOT)JTDMJOJDBMFYQFSUJTFJTJO centers research Current sedation. and management pain injury, brain traumatic manage pediatric pain pre-hospital on QSPWJEFST%S)FOOFTSFDFJWFEIJTNFEJDBMEFHSFFGSPN"JO4IBN $BJSP &HZQU JO BOEIJT.4JOCJPTUBUJTUJDTGSPNUIF. 8JTDPOTJO .JMXBVLFF JO"ęFSDPNQMFUJOHIJTQPTUHSBEVBU &HZQU IFNPWFEUPUIF6OJUFE,JOHEPNGPSBEEJUJPOBMUSBJOJOHC UPUIF6OJUFE4UBUFT)FDPNQMFUFEIJTHFOFSBMQFEJBUSJDUSBJOJ )PTQJUBM PG 8JTDPOTJO .JMXBVLFF JO CFGPSF KPJOJOH.FEJDBM$PMMFHFPG8JTDPOTJOBTB1FEJBUSJD&NFSHFODZ.FEJDJOF UIF GB UP*O %S)FOOFTDPNQMFUFEBGFMMPXTIJQJO&NF 4FSWJDFTBOEDVSSFOUMZTFSWFTBTUIF"DBEFNJD1FEJBUSJD4PDJFUJ &NFSHFODZ.FEJDBM4FSWJDFTGPS$IJMESFO &.4$ )FBMTPTFSWFE SFHJPOBM OBUJPOBMBOEJOUFSOBUJPOBMDPNNJUUFFTćF#VTJOFTT+P IJNPOFPGUIF#FTU1FEJBUSJD&N Division faculty diverse research and administrative have interests, offering pediatricthe medicine fellows emergency BVOJRVFPQQPSUVOJUZUPTFMFDUUIFBQQSPQSJBUFNFOUPSXJUIJOUF *OBEEJUJPO GBDVMUZBOEGFMMPXTQMBZBNBKPSSPMFJOUIFFEVDB 6OJWFSTJUZ t %S3FBHBOO.D$SFBSZDPNQMFUFEBDPNCJOFEQFEJBUSJDTBOEFNF t %S+FOOJGFS1BQFDPNQMFUFEIFSSFTJEFODZBU%VLF6OJWFSTJUZ t %S%BOF'MJFEOFSKPJOFEVTBęFSUISFFZFBSTBT"TTPDJBUF$M well-established, The clinically pediatric strong medicineprogram fellowship emergency recruits per fellows three *SWJOFBOEUISFFZFBSTXJUI"DVUF,JET6SHFOU$BSFJOUIFOPS year. 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The The verydivision had a successfulrecruiting addingoutstandingfour season new faculty: in 2010, t %S3IJBOOPO)VMMDPNQMFUFEIFSQFEJBUSJDSFTJEFODZBU654P The emergency department at Children’s Medical departmentemergency is The only at Children’s Center the 1 pediatricLevel Texas, Northtraumain center the pediatric of busiest and medicine one emergency clinical services pediatric19 in Division has the The country. medicineemergency three faculty, general pediatric faculty and nine dedicated advancing to fellows the care acutely of ill and children injured through clinical service, and research. education Emergency Medicine 56 6OJWFSTJUZPG3PDIFTUFS /: 'FMMPX 1FEJBUSJD&NFSH *OUFSO (FOFSBM4VSHFSZ /FX:PSL.FEJDBM$PMMFHF .BOIBU Post-doctoral training: Education: injury 'FMMPX 1FEJBUSJD&NFSHFODZ.FEJDJOF Post-doctoral training: expertise: Clinical/research "TTJTUBOU1SPGFTTPS Badawy,Mohamed K. 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Wiebe, $IBJS $PNNJUUFFPO$POUJOVJOH.FEJDBM&EVDBUJPO "NFSJDBO"DBE $IBJS 4VCCPBSE1FEJBUSJD&NFSHF .FNCFS $PNNJUUFFPO1FEJBUSJD&NFSHFODZ.FEJDJOF 5FYBT1FEJBU 4FDUJPO&EJUPS &/54FDUJPO 1&.TPę 1FEJBUSJD&NFSHFODZ.FEJDJ &EJUPSBOE.BKPS$POUSJCVUPS 1&.1JY IUUQXXXBBQPSHNPDQF .FNCFS &EJUPSJBM#PBSE 13&1&.FE 1FEJBUSJDT3FWJFXBOE&EVD .FNCFS $PNNJUUFFPO1FEJBUSJD&NFSHFODZ.FEJDJOF 5FYBT1FEJBU .FNCFS /"$)3*2VBMJUZ*NQSPWFNFOU$PNNJUUFF4UFFSJOH$PNNJUUFF .FNCFS /"$)3*1FEJBUSJD1BJO.BOBHFNFOUJOUIF&NFSHFODZ%FQBS #PBSE.FNCFSBOE7PMVOUFFS 'SJTDP,JET$MJOJD %JSFDUPS %JWJTJPOPG1FEJBUSJD&NFSHFODZ.FEJDJOF .FEJDBM%JSFDUPS &NFSHFODZ4FSWJDFT $IJMESFOT .FNCFS #PBSEPG%JSFDUPST %BMMBT1IZTJDJBOTGPS$IJMESFO t i(FOJUPVSJOBSZ&NFSHFODJFTJO$ Craig J. Huang, M.D. Huang, Craig J. Bansal, M.D. Beatrix t %FWEBT( 4DPUU4 8JFCF3" ,FMMZ/ )JDLT1 0LBEB1i"4V M.S. M.D., Hennes, Halim Major Administrative or Leadership Responsibilities Major Administrative
Robert A. Wiebe, M.D. Robert A. Wiebe, t .PPSF$1 )VBOH$ 3PESJHVF[" 8JFCF3" 4JFHFM+i1SFTFOU t i&/5&NFSHFODJFTJO,JET w&NFSHF Emergency Medicine 64 Endocrinology 65 Perrin White, M.D. White, Perrin Director, Pediatric Endocrinology Pediatric Director, , from , from magna cum laude cum magna Endocrinology caring children with diabetes in for the Dallas area. metropolitan only major program major only Harvard College, Cambridge, Massachusetts, in 1972, and his M.D. from from his M.D. in 1972, and Massachusetts, Cambridge, College, Harvard held residencies in 1976. He School, Boston, Massachusetts, Medical Harvard 1976 to from Maryland, Baltimore, Hospital, Hopkins Johns in pediatrics at he held a research 1981, and 1980 to from Hospital York New at 1978 and New University, Rockefeller biology at molecular in developmental fellowship honors, and awards of a number has received 1980. He 1978 to from York, the Endocrine of Society the and Award Oppenheimer the Ernst including has served He on Research. the Society Pediatric of for Award Mead-Johnson on and Health of Institutes the National for advisory committees numerous boards. several editorial We are the We Perrin C. White, M.D., Professor, was the first to hold the Audre Newman Audre to hold the was the first Professor, M.D., C. White, Perrin was recruited He Endocrinology. in Pediatric Chair Rapoport Distinguished in Endocrinology program the Pediatric of as Director Southwestern UT to he was where York College in New Medical Cornell University 1994 from several diseases genetic has studied of White Dr. Pediatrics. of Professor the most common metabolism including and biosynthesis hormone steroid he has concentrated recently More hyperplasia. adrenal congenital of forms blood in white expression gene of studies including research translational on a pilot and mellitus 2 diabetes Type 1 or Type either with children cells from new- with in patients anakinra, agent, anti-inflammatory a potent of study his A.B., received White Dr. 1 diabetes. Type onset Faculty
Teaching is a top priority, and several and local faculty fellows priority, won is a top teaching have members awards from medicalTeaching A high community residents. on valuestudents or placed is service. two at Many local faculty volunteer members diabetes camps run the by division, and two serve as medical directors the camps. for The fellowship program itsfellowship accepted The first extramural 1999 fellowyear, and per in fellows hasall to accept grown two been fully have whom of American-trained. half from the Approximately medical come own the of fellows school’s pediatricprogram program. residency fellowship The emphasizes bothbroad deep clinical and trainingwell as as experience inclinical as both. their projects research or research, All published bench fellowship have the of fellows literature, in papers peer-reviewed and more the or division majorityone of graduates take UT academic at positions other medical or Southwestern schools. The division was created 15 years 15 The division wasago has and created a grown minimumfrom of 14 three facultyfull-time to members and faculty degrees. active Five have twoPh.D. members or part-time faculty also three members, M.P.H. whom have of funding. competitive research programs received that have The Division of Pediatric Endocrinology undertakes teaching, research and clinical care of patients with diabetes, diabetes, with patients of care clinical and research teaching, undertakes Endocrinology Pediatric of Division The obesity and endocrine thatdisorders affect growth,or pubertal the functionof endocrine development the glands, such as the thyroid and the adrenals. of largest one is such divisions It in the country and program is the only major caring children for with diabetes in the Dallas metropolitan area. Because the division cares such a large number for childrenof with these within disorders a very 150-mile radius large area to catchment - a 100 in directions most - it training fellowship provide is in to a unique position clinical and conduct research. Endocrinology 66 Post-doctoral training: Post-doctoral training: M.D., FL, 2001Medicine, Education: hypocalcemia Research expertise: expertise: Clinical Professor,Assistant Pharmacology and Pediatrics Soumya Adhikari, M.D. Post-doctoral training: Education: expertise: Clinical Professor Assistant Clinical M.D. Ernesto Fernandez, Pediatric Endocrinology, 1988-1990 Endocrinology, 1987-1988; Children’s Center, OH, Fellow, Medical Hospital Cincinnati, 1984-1987;Resident, Pediatrics, Science Antonio, Center at Fellow, San Health UT Pediatric Post-doctoral training: Education: insufficiency adrenal iatrogenic and obesity hypothalamic patients, oncology expertise: Clinical Associate Professor M.D. Dickson, A. Bryan 2007; Fellow, 2007-2010 Endocrinology, Pediatric Post-doctoral training: Education: Research expertise: expertise: Clinical Professor Assistant Amy Mathew M.D. Burton, Fellow, 2006-2007 Clinical 2003-2006; Research, Endocrinology Fellow, Angeles, Los University of Institute, Howard California, Hughes Medical 2006; 1998-2001; Fellow, Angeles, Endocrinology, 2002- Pediatric University of California-Los Post-doctoral training: Haven, CT, M.D., 1998 1987; University of California-Berkeley, Ph.D., 1992; Yale University New School of Medicine, Education: homeostasis energy of regulation Research expertise: expertise: Clinical Professor,Assistant Pharmacology and Pediatrics Kamal Bharucha, Ph.D. M.D., Fellow,Southwestern, 2004-2007 Endocrinology, Pediatric University of Florida, Gainesville, B.S., 1996; University of Miami School 1996; of University B.S., of Miami University Gainesville, of Florida, UT Austin, B.A., 1984; UT Southwestern, 1984; B.A., M.D., UT Austin, 1988 UT Science Antonio, Center at San M.D., Health 1980; UT 1984 B.S., Arlington, UT Texas Tech 2000; B.S., University School Dallas, M.D., of Medicine, UT 2004 University City of College, New York, Brooklyn NY, B.A., Pediatric endocrinology Pediatric Diabetes neuro- in disorders endocrine endocrinology, particularly Pediatric prevetion treatment and obesity Types 2diabetes, 1and endocrinology Pediatric Preservation of beta cell function in Type in neonatal function 1diabetes, of cell beta Preservation Type 2 diabetes, behavior changing counseling Type behavior changing 2diabetes, and flies) (fruit diseases Drosophila foras a model metabolic organism UT Southwestern, Resident, Pediatrics, 1988-1991 Southwestern, Resident, Pediatrics, UT Hospital, County Science Center Antonio/Bexar at San Health UT 2004- Resident, Pediatrics, at Birmingham, University of Alabama MD, Resident, Hospital, Pediatrics, Baltimore, Johns Hopkins UT Southwestern/Children’s, 2001-2004;UT Resident, Pediatrics, UT summa cum laude summa cum , Endocrinology 67 , 1992; University University , 1992; magna cum laude , B.A., 1988; UT Southwestern, M.D., Ph.D., Ph.D., UT M.D., , B.A., Southwestern, 1988; cum laude cum University of South of Carolina University Medicine/Richland of School Memorial Cleveland Clinic Internal Resident, OH, Medicine, Foundation, 1998- Illinois of University Pediatrics, Chicago, Resident, at 2002- University Hospitals of Cleveland/Rainbow Babies and Children’s Cleveland/Rainbow Hospitals of University and Children’s Babies UT Southwestern/Children’s, Resident, Pediatrics, Resident, UT UT 1999-2002; Southwestern/Children’s, Development of the of mammalian Vitamin growth of Development role plate, long-bone diabetes obesity Lipodystrophy, inIncretin types physiology 1 and 2 diabetes, incretin-based treatments Gene expression in 2 diabetes leukocytes expression Gene 1 and Type in Type Obesity, diabetes, growth, Obesity, throid, puberty 1 and 2 diabetes Types Pediatric particularly endocrinology, obesity and growth disorders Pediatric endocrinology Pediatric endocrinology Wellesley College, MA, MA, College, Wellesley North of Carolina University CA, B.A., College, Claremont, 1992; School Pomona La 2000 Salle Universidad M.D., Mexico, Medical Mexico City, School, University of South Carolina, of University B.S., Columbia, Washington University, St. Louis, MO, B.A., 1996; Creighton University School School University St. Louis, B.A., Creighton 1996; MO, University, Washington of South 1996 Carolinaof Medicine, M.D., Columbia, of School training:Post-doctoral Hospital, Columbia, Resident, Pediatrics, 1996-1999; UT Southwestern, Fellow, Pediatric UT Fellow, Southwestern, Pediatrics, Columbia, Resident, Hospital, 1996-1999; 1999-2002 Endocrinology, Ximena López,Ximena M.D. Assistant Professor Clinical expertise: Research expertise:Research expertise:Research Roy Kim, M.D., M.P.H. Roy Pediatrics and Internal MedicineAssistant Professor, Clinical expertise: D deficiency D deficiency in type 2 diabetes Education: Education: North of Carolina University Public Health, Medicine, of of Hill, School Chapel 1997; M.D., 1998 Hill,Chapel M.P.H., training:Post-doctoral Pediatric Endocrinology, 2002-2005 Fellow, Philadelphia, Hospital2002; of PA, Children’s typesfor 1 and 2 diabetes Education: training:Post-doctoral 2005; Massachusetts General Pediatric Hospital/Harvard Fellow, Medical Boston, School, 2005-2008,Endocrinology, Joslin Diabetes Center/Harvard Medical Clinical Boston, School, 2006-2008Research Fellow, Assistant Professor Clinical expertise: expertise:Research Michele R. M.D., Ph.D. Hutchison, Assistant Professor Clinicalexpertise: Melissa R. M.D. Ham, Melissa Education: Ellen K. Grishman, M.D. K. Ellen Grishman, Assistant Professor Clinical expertise: Research expertise:Research Education: Medicine,of Omaha, NE, 2000; M.D., UT Clinical Southwestern, Clinical Research Scholar, 2008-2011 Sciences, training:Post-doctoral Pediatrics, Resident, OH, Hospital, 2000-2003; Pediatric UT Southwestern, Fellow, 2003-2006 Endocrinology, Southwestern, Fellow, Pediatric Endocrinology, 2002-2004Southwestern, Fellow, 1999 training:Post-doctoral Endocrinology 68 Since 2002, the division has has division the Since 2002, Southwestern, Fellow,Southwestern, 2007-2010 Endocrinology, Pediatric training: Post-doctoral Southwestern, M.D., 2004 Southwestern, Fellow, Pediatric Endocrinology, 2006-2009 Fellow,Southwestern, Endocrinology, 2006-2009 Pediatric training: Post-doctoral M.D., 2003 at Houston, Fellow, Endocrinology, 1996-1998 Pediatric 1992-1994;Pediatrics, Fellow, Endocrinology, 1994-1996; Pediatric Science Center Health UT 1991-1992; OH,Cleveland, Intern,Pediatrics, Resident, Francisco, San University of California training: Post-doctoral Galveston, M.D., 1991 Education: function muscle in dehydrogenase 6-phosphate Research expertise: Professor Assistant D. Randy McMillan, Ph.D. Education: Research expertise: Clinical expertise: Professor Assistant Sumpter,Kathryn M.D. Education: disease to human how it pertains Research expertise: Clinical expertise: Professor Assistant M.D. Stewart, Ryan 2004 Post-doctoral Fellow,Endocrinology, Research 2000-2003; Endocrinology, Pediatric 2003- Center, Fellow, 1997-2000; NC, University Medical Pediatrics, Duke Durham, Pediatric training: Post-doctoral Center, Sciences University Health Lubbock, M.D., 1997 Education: Clinical expertise: Professor Assistant Jon D. Oden,M.D. Education: Clinical expertise: Professor Assistant Clinical Mootha, M.D. Sudha L. of Lubbock, Medicine, Ph.D., 1991 Rice University, Rice Houston, B.A., TX, Texas University, A&M Station, College B.S.E.E., Baylor University, Waco, B.A., TX, Angelo State University, 1979; M.S., Angelo, Texas TX, San Tech University School Texas Tech University, Lubbock, B.S., more than doubled Pediatric endocrinology Pediatric thyroid pump, growth, insulin Diabetes, obesity resistance, endocrinology, Pediatric insulin endocrinology Pediatric Role of Gprotein-coupled large receptors development, in role of hexose- Immunomodulation of Type 1diabetes Using UT Southwestern/Children’s, Resident, Pediatrics, 2004-2007; UT UT 2004-2007; Southwestern/Children’s, UT Resident, Pediatrics, UT Southwestern/Children’s, Resident, Pediatrics, 2003-2006; UT UT 2003-2006; Southwestern/Children’s, UT Resident, Pediatrics, Western Case University/Rainbow Babies Children’s and Hospital, Texas Tech Center, Sciences University Health Lubbock, Resident, Drosophila to demands meet of rising the community. the as an animal model for lipodystrophy and congenital animal an as summa cum laude summa cum summa cum laude summa cum magna cum laude cum magna magna cum laude cum magna , 1987; at Branch Medical UT , 1997; Southwestern, UT , 1993; Texas Tech , 1991; UT Endocrinology 69 Actions of IGF-1 (insulin-like growth growth (insulin-like IGF-1 of Actions Transient neonatal hypocalcemia: hypocalcemia: neonatal Transient Transition of care in adolescents with with in adolescents care of Transition Teena Thomas, M.D. Thomas, Teena interests: Research outcomes and presentation Shona Rabon, M.D. Shona interests: Research diabetes Ryan Stewart, M.D. Ryan UT Southwestern Professor, Assistant interests: Research (fruit flies) as a modelfor Drosophila lipodystrophy Susan Hsieh, M.D. Hsieh, Susan interests: Research plate the growth at factor) Columbia-Presbyterian Medical Center, New York, NY, Resident, Resident, NY, Columbia-Presbyterian York, New Medical Center, Pediatric endocrinology The role of endocrine malfunctionrole The The role of p53 in modulating insulin insulin of p53 in modulating role The Vitamin D deficiency in obesechildren Vitamin leading to abnormal growth in sickle cell growth abnormal to leading disease Todd Alonso, M.D. Alonso, Todd interests: Research Alejandro de la Torre, M.D. de la Torre, Alejandro interests: Research action Hillary M.D. Lockemer, interests: Research Research interests: Research D deficiency type and 2 diabetes Vitamin in children Micah M.D. Olson, Endocrinologist, Phoenix Pediatric Hospital Children’s Washington University, St. Louis, MO, A.B., 1981; Washington University Medical University Washington St. Louis, A.B., 1981; MO, University, Washington 1st Year 1st 2nd Year 2nd Year 3rd Year Year 3rd Completed June 2009Completed June Post-doctoral Fellows Fellows Post-doctoral Clinical Assistant Professor Clinical expertise: Pediatric endocrinology Research expertise: Behavioral in interventions type 1 diabetes patients Arkansas of AR, University Medical B.A., Hendrix for 1995; Education: College, Conway, 1999 Medicine,Sciences, Little College of M.D., Rock, NC, Winston-Salem, training: Baptist MedicalPost-doctoral University Center, Forest Wake Pediatrics,Resident, Pediatrics, Chief Resident, 1999-2002; 2002-2003; UT Southwestern, Pediatric 2004-2007 Endocrinology, Fellow, Y.C. Annie Wang, M.D. Wang, Annie Y.C. Education: 1985 St. M.D., Louis,School, MO, Post-doctoral training: Fellow, Medical Hospital/Cornell University Center, York New Pediatrics, 1985-1988; Energy of Inherited Metabolism, Disorders for Center 1988-1991; Pediatric Endocrinology, Pediatric Metabolism, 1991-1993; Fellow, Cleveland, OH, ReserveCase University, Western Metabolism Training Molecular Fatty Oxidation, Program, of Biology Acid 1993-1997 Fellow, Grace M. Tannin, M.D. Grace M. Tannin, Professor Associate expertise: Clinical Endocrinology 70 clinic continues to provide the only comprehensive program for childhood obesity in North Texas, with more than Texas, more continues to comprehensive provide North only than in clinic the with obesity for childhood program thefrom Joint Health Commission. The Center and in its Consequences certification Obesity for specific (COACH) to disease- receive the country in program pediatric first the also was diabetes Theprogram Association. Diabetes American Typethe both Texasby in Type 1and isone programs and of certified four 2diabetes only pediatric for educationnew patient yearly. consultations program acomprehensiveprovides Program The Diabetes bilingual Center sessions per 2,500 including approximatelyweek provides for clinic Endocrinology The patients, half-day 10 diabetes. provide and obesity comprehensive disorders, endocrine with for care children who year this members 2010. faculty in and part-time visits 13,000 comprisesdivision to more Thefull- year than 15 per visits volume 5,000 from clinical in increase to doubled meet the more size has in division than the Since 2002, the community. of demands growrising continuesthe rapidly to to meet Endocrinology The Division of Pediatric Activities Clinical factor-1. growth hormone insulin-like and termed growth plates and industry-sponsored clinical researchFinally, Dr. Hutchison conducts on basic zones research NIH-supported of how cartilage on bones grow at specialized the therapy of short stature with the growth predisposingto Type changes biochemical with 2diabetes. isassociated found this has that and clinic obesity Ddefciency the among patients in prevelance of high vitamin very found a Type also She has with 2diabetes. dependence among children of progression history to insulin natural the flies). in Drosophila and fat genes(fruit storagemetabolism influencing identify MicheleDr. studied has Hutchison to istrying Bharucha Type and on Dr. research obesity members conducting are 2diabetes. Kamal faculty Several to relatedused agent.powerful safely be might it if see to diabetes 1 Type new-onset amore with planned are with studies Additional secretionprolong remains. honeymoon some which the in period insulin children in — anakinra — agent anti-inflammatory Sumpter have conducted of apilot apowerful study Kathryn and happens. Additionally, Adhikari Soumya Drs. this pathways by which signaling intracellular the to eludicate try and to inflammation responsible this for triggering —are acids fatty —such as serum to seewhat in factors studies tube test in results up these following are White Supported Foundation, Juvenile by Research the Diabetes Dr. she diagnosed. and are Perrin when children time the around cells these areprominent in very of inflammation signs found who has that Grishman, Kaizer Ellen of responses) gene immune (which blood expression peripheral cells mediating in conducted includes cells by Dr. Research within theResearch Activities division is grouped into several Technician Research II main themes.Alaina Watson Research Eugene Center McDermott Assistant, Student Research on Type 1 diabetesKristen Tolson includes Scientist Research studies Rogoff,Daniela M.D., Ph.D. Eugene II, Center McDermott Assistant Research Vidya Rai Scientist Research Suprabha Pulipparacharuvil Associate Research Higgins Kelli Technician Research II Michelle Castro Technician Research Eugene II, Center McDermott Amin Viren Staff Clinical/Research Endocrinology 71 crinologists, Dallas, August Dallas,crinologists, August trophy,” Endocrine Grand Rounds, UT Southwestern, UT Southwestern, Rounds, Endocrine Grand trophy,” Association of Clinical Endo of Association 2010 Director, Division of Pediatric Endocrinology Pediatric of Division Director, Program Endocrinology Fellowship Pediatric Director, Clerkship Student Medical Pediatrics Director, Children’s Endocrinology Center, Director, Medical Services, Children’s Network and Ambulatory Co-director, Physician Information) Record/Health Health (Electronic HER/HIM Committee Chairman, Foundation Diabetic Southwestern Board, Executive Member, Texas Gainesville, Children), for Camp (Diabetes Sweeney Camp Director, Camp Foundation Children for Physicians President, Foundation Diabetes Juvenile Board Member, Diabetic Foundation Southwestern Board Member, Program Endocrinology Fellowship Pediatric Director, Associate Committee Endocrinology Oversight Scholarship Pediatric Chair, April 2010 April and Meeting ENDO 2010: The 92nd Annual Lipodystrophy,” Congenital for Organism as a Model “Drosophila 2010 CA, June Diego, San Expo, the American of Chapter Texas Puberty,” of “Disorders “Medical Best in Education Achieve Electronic Utilization,” to the Council of Health Age How on Records: AnnualMedical Meeting, Education in NM, Student March Pediatrics 2010 Albuquerque, (COMSEP) 2008-present Students, Medical 2nd Year Endocrine Pharmacology Lecturer, December 2010 Children’s, Rounds, Grand Pediatric Overview Childhood the Genetics of Obesity,” of “An 2010 Dallas, March Hospital, City Medical Rounds, Grand Pediatric Diabetes,” of “Treatment Practitioners Nurse Pediatric Care Acute Practitioners,” Nurse Pediatric Care Acute “Endocrinology for 2010 April UT Arlington, Program, Lipodys Congenital for Organism as a Model “Drosophila Perrin C. White, M.D. C. White, Perrin t t M.D. Adhikari, Soumya t Bryan M.D. A. Dickson, t t t t M.D. Fernandez, Ernesto t t t t M.D. R. Ham, Melissa t Ph.D. M.D., Michele R. Hutchison, t Major Administrative or Leadership or Responsibilities Major Administrative t M.D. Tannin, Grace t Kamal Bharucha, M.D., Ph.D. M.D., Bharucha, Kamal t t M.D. R. Ham, Melissa t t Stewart, M.D. Ryan t Soumya Adhikari,Soumya M.D. t Presentations/Teaching Activities Presentations/Teaching The endocrinologyThe service inpatient providesmore thancarefor 600 patients admittedto servicethe including yearly, 260 with patients diabetes. onset new In addition, the Endocrinologyservice inpatient will 300 approximately provide other services to consultations during the same time period. The development of clinicalof research development studiesThe and interventional trials has significantlyincreased in the division the past yearover anand provides opportunity incorporate leading-edge to technology the into care the of patient population. 600 referrals Expansion year. per visits the of Legacy clinic at the to campus 1,100 Children’s approximately provides per year in this fast-growing area North of Texas. Endocrinology 72 t K.Grishman, M.D.Ellen Awards andHonors t t t Grace M.Tannin, M.D. t t Jon Oden,M.D. Clinical Research Scholar, Department UTSouthwestern, of ClinicalSciences, 2008-2011 Member, ADA National Camp Workgroup Member, ADA Dallas Advisory Board Medical Director, Camp New Horizons (American Diabetes Association camp) Medical Director, Camp Sweeney (Diabetes Camp for Children), Gainesville, TX Clinical Director, COACH Clinic,Children’s Gastroenterology 73 John M. Andersen, M.D. Director, Pediatric Gastroenterology Pediatric Director, in North Texas North in clinical specialties and areas of research research of areas specialties and clinical Gastroenterology , Professor is the Director of Pediatric Pediatric of is the Director , Professor major program program major The caring for children with disorders. children caring gastrointestinal for Chronic abdominalChronic anesthesiology/pain pain psychology) management, (GI, pulmonary, psychology) ENT, Aero-digestive (GI, disorders nutrition,pulmonary, psychology) (GI, Cystic fibrosis nutrition, psychology) Inflammatory (GI, disease bowel Intestinal and nutrition psychology) surgery, failure (GI, Gastroenterology at UT Southwestern and Children’s Medical Center. In addition addition In Center. Medical Children’s and UT Southwestern at Gastroenterology his pediatric gastroenterology, general to disease eosinophilic and bowel inflammatory syndrome, cyclic vomiting are Texas, Sherman, College, Austin from Andersen graduated Dr. esophagitis. the University from his medical degree 1970 he received in 1966. In a B.A. with from he interned where in Philadelphia, Medicine School of Pennsylvania of UT Southwestern/ at his residency in Pediatrics completed 1971. He 1970 to at Metabolism Lipid and in Gastroenterology a fellowship in 1975 and Children’s in 1978. UT Southwestern John M. Andersen, M.D. John M. Andersen, Faculty Specialized multidisciplinary clinics include: t t t t t annually)Six gastroenterology (two fellows train in research basic areas throughout UT Southwestern: hepatobiliary transport physiology, eosinophilic esophagitis, pathobiology of pruritus associated with chronic liver disease, disease, liver metabolic and IBD. immunobiology of Under Dr. Michael Russo’s leadership, the full leadership, Michael Russo’s service Legacy at Dr. consultative is thriving practice outreach Children’s Under at with three full-time and three part-time Next providers. year opening anticipate we an consultation GI outreach Southlake. in clinic In the addition to faculty additions, three practitioners, Mackling, nurse Jody Alstyne, Constance Van LaJontee and three the assistants, joined Xu, physician divisionWare, staff to Tracy Devechio Edwards, Trant, Heather the intestinal liver, established unit failure to newly devoted inpatient and transplantation.six These practice advanced additionalnursepractitionersworking five join GI primarily providers clinics. in outpatient the gastroenterologists, Drs. Aakash Goyal, Koorosh Kooros and Charina Ramirez, increasing the number of full time time full of number the increasing Ramirez, Charina and Kooros Koorosh Goyal, Six Aakash additional are recognize to faculty pleased our recruitment division three joined We of last year. additional clinical Drs. gastroenterologists, gastroenterologists thirteen. to full our Reed, group Gabriela joined psychologist, InDr. addition, time. two Finally, Drs. investigators, Amal science basic new Dutta in and Qin the Li, work general area regulation of hepatobiliary of Andrew under thesecretion Feranchak. aegis Dr. sixteen of are There faculty Southwestern our in division. As the major programAs the caring major in North children Texas for withgastrointestinal disorders, the Division of (GI) Gastroenterology at UTrecognized Southwesterndivision distinguishedincludes individuals including focusing areas diverse on Gastroenterology, of provides patient-centeredmolecular disease, liver viral chronic cholestatic of biology neurogastroenterology, hepatitus, inflammatory bowel care to and intestinal andisease, and therapeutic rehabilitation transplantation endoscopy, and liver intestine. of ever expanding population. This nationally Gastroenterology 74 Bradley A. Barth, M.D. Bradley Barth, A. Pediatric Gastroenterology, Nutrition, 2001-2004Pediatric Hepatology and 1998-2001; Resident, University,Boston, Pediatrics, MA, Fellow, Harvard Boston, MA, Post-doctoral training: Science Center Antonio, at San M.D., Health UT 1998 Education: endoscopy capsule and strictures management of esophageal bleeding, of chronictreatment gastrointestinal acute and expertise: Clinical Unit Endoscopy Gastroenterology Director, Professor Assistant Michigan, Detroit, Fellow, Detroit, Gastroenterology,Michigan, Nutrition, Pediatric 2007-2010 Hepatology and Children’s 2006-2007; Resident, Chief Pediatrics, of Hospital 2004-2006; Resident, Pediatrics, Center, 1999-2002; University NY, Brookdale Medical Pediatrics, Hospital and Brooklyn, Post-doctoral training: Education: Research expertise: expertise: Clinical Professor Assistant Aakash Goyal, M.D. Fellow,Research 1998-1999 Center, Denver, Fellow, Gastroenterology, Nutrition, 1995-1998; Hepatology Pediatric and PA,Pittsburgh, 1992-1995; Resident, Pediatrics, University Sciences of Colorado Health Post-doctoral training: PA,Medicine, M.D., 1992 Education: secretion biliary of regulation purinergic formation, bile of mechanisms Research expertise: expertise: Clinical Associate Professor P.Andrew M.D. Feranchak, 2006-2009 Gastroenterology, Fellow Southwestern, Pediatric UT JSPS Japan, Fellow, 2004-2006; Okazaki, Sciences, Physiology, Associate, for Research Japan, Institute National Physiological 2003-2004; Surgery, and 1991-1992;Medicine for Okazaki, Physiological Sciences, Institute National Post-doctoral training: Ph.D., Japan, 2003 Okazaki, Sciences, Physiological Education: functions epithelial in channels -activated Ca2+ mechanosensitive and pathways, liver, the signaling of in ion purinergic channels regulation and characterization Research expertise: Instructor Ph.D. Amal M.B.B.S., Dutta, Fellow,Southwestern, Gastroenterology, 2005-2008 Pediatric State University/Children’s UT 2002-2005; Resident, Detroit, Pediatrics, of Hospital Michigan, Post-doctoral training: 2000 Trinidad, M.B.B.S., Augustine, Education: expertise: Clinical Program Rehabilitation Director, Intestinal Professor Assistant M.D. Channabasappa, Nandini UT Austin, TX, B.A., 1993; B.A., Houston, School TX, of UT Health, Public Austin, M.P.H., UT 1995; B.J. Medical College/University of Pune, Maharashtra, India, M.B.B.S., 1999 M.B.B.S., India, Maharashtra, College/University of B.J. Pune, Medical University 1988; of B.S., IN, School Notre University of Dame, of Pittsburgh 1991; M.B.B.S., Bangladesh, University The Graduate of Rajshahi, of University Vanderbilt 1993; University, B.S., TN, University West of the Nashville, St. Indies, Therapeutic endoscopy in children including ERCP,including Therapeutic endoscopy children in enteroscopy, balloon Inflammatory bowel disease, liver diseases, growth and malabsorption growth liverdiseases, bowel disease, Inflammatory endoscopy rehabilitation, therapeutic and failure Intestinal Pediatric gastroenterology Pediatric Inflammatory bowel disease and bowel it complicationsdisease Inflammatory transport, fibrosis, hepatobiliary cystic Cholestatic liver disease, secretion bile formation, and functional of biliary Mechanisms Tufts-New England Medical Center/Floating Tufts-New forHospital Children, Medical England Government Medical College, Patiala, Punjab, India, Resident, Punjab, India, Patiala, College, Government Medical Center/Children’s Medical University of Pittsburgh Hospital of Resident, and Intern Hospital, Bangladesh, College Medical Rajshahi Wayne 2002; Ford Henry Pediatrics, Intern, Hospital, MI, Detroit, Gastroenterology 75 APA-Approved Internship, UT Southwestern; Fellowship, Pediatric UT Internship, Southwestern; Fellowship, APA-Approved UT Southwestern/Children’s, Resident, Pediatrics, Resident, UT Southwestern/Children’s, 2003-2006; UT Scott & White Hospital, Temple, TX, Pediatrics, Resident, 2000-2003; Scott & White Temple, Hospital, University MedicalUniversity Pediatrics, Pecs, Resident, Hungary, of School 1991- Niemann-Pick typeNiemann-Pick C disease, fatty disease liver Liver failure, Liver hepatitis B, hepatitis C FIC-1 and progressive familial and progressive cystic FIC-1 intrahepatic cholestasis (PFIC), Inflammatory disease bowel Pediatric gastroenterology, inflammatoryPediatric gastroenterology, disease bowel Psychological evaluation inflammatory and Psychological of treatment disease, bowel Endoscopic ultrasound, Endoscopic gastrointestinal in disorders spectrum autism Pediatric gastroenterology, liver disease, liver Pediatric gastroenterology, transplantation, liver hepatitis C Metabolic liver disease, liver Metabolic inflammatory disease bowel Endoscopic ultrasound, Endoscopic inflammatory disease, bowel gastroesophagealreflux University of Puerto Rico, Cayey, B.S., 1990; University of Puerto B.S., of 1990; Rico-School Puerto University of of Rico, University Cayey, Texas A&M University, College B.S., 2007. Station, 2003; UT Ph.D, Southwestern, A&M University, Texas University of Houston, TX, B.S., UT Houston, of 1999; Medical University Galveston, Branch at M.D., Medical College of Wuhan University, Wuhan, China, M.D., 1985; Tongji Medical Tongji Wuhan, China, 1985; Medical M.D., Wuhan University, College of Health A&M University Sciences Atlanta, Texas GA, B.S., Emory 1995; University, University Medical School of Pecs, Hungary, M.D., cum Medical University 1991 M.D., Pecs, laude, Hungary, of School Norberto Rodriguez-Baez, M.D. Professor Associate Director, Gastroenterology Fellowship Clinical expertise: expertise:Research Psychologist Clinical Expertise: Education: 1994 Medicine, San Juan, M.D., training:Post-doctoral Puerto of Rico-School Medicine, University of San Juan, Intern, Medicine, of School Stanford University Pediatrics, Resident, 1995-1997; Pediatrics, 1994-1995; and 1998-2001 Hepatology Nutrition, Pediatric Gastroenterology, Palo Alto, CA, Fellow, Gabriela M.Gabriela Reed, Ph.D. Research expertise:Research functional disorders, abdominal bowel pain, and encopresis. constipation, Education: Post-Doctoral Training: 2007 Children’s, Psychology, Assistant Professor Clinical expertise: Charina M. Ramirez, M.D. Charina Education: 2003 training:Post-doctoral Pediatric GastroenterologySouthwestern, Fellow, and 2007-2010 Nutrition, Assistant Professor Clinical expertise: expertise:Research Ashish S. Patel, M.D. S. Patel, Ashish fibrosis transmembranefibrosis (CFTR)biliary regulator conductance and secretion Education: Wuhan, China, Ph.D., M.Sc., 1997; and Science Technology, of College, University Huazhong 2001 Education: 2000 Medicine, College M.D., of College Station, Center, training:Post-doctoral 2003-2006 Pediatric Gastroenterology, UT Southwestern, Fellow, Instructor expertise:Research disorders Education: training:Post-doctoral University Center, Hospital St. Luke’s-Roosevelt Pediatrics,Chief Resident, 1994; 1994-1995; Tufts-New Pediatrics, Resident, 1999-2001; NY, York, and New Surgeons, Physicians College of Pediatric GastroenterologyEngland MA, and Boston, 2001-2004 Nutrition, Fellow, Medical Center, M.D., Ph.D. Qin Li, Research expertise:Research Koorosh Kooros, M.D. Assistant Professor Clinical expertise: Gastroenterology 76 3rd Year JuneCompleted 2009 Post-doctoral Fellows disease Niemann-Pick Cand type Wolman Research interests: Amal Aqul, M.D. Regulation of bile formation Research interests: Hospital, Greenville, SC Pediatric Gastroenterologist, Children’s Michael Dougherty, D.O. Cholesterol transport in metabolism 1999-2001; Fellow, Southwestern, Nutrition, 2001-2004 UT and Gastroenterology Post-doctoral training: ofMobile,College Medicine, M.D., 1998 Education: Clinical expertise: expertise: Clinical Legacy at Children’s Gastroenterology, Pediatric Director, Professor Assistant Russo,Michael A. M.D. School, Boston, MA, Fellow,School, Boston, Nutrition, MA, 2001-2004 and Gastroenterology Fellow, 1998-2000; Medical Gastroenterology,Resident, Pediatric 2001; Pediatrics, Harvard 1995-1996; Center/Floating at Hospital Tufts, for Children Medical Boston,MA, New England Post-doctoral training: Education: Research expertise: expertise: Clinical Professor Assistant Gaith S.Semrin,M. M.D. Nutrition, 2006-2009 Fellow,Southwestern, and Gastroenterology Pediatric Post-doctoral training: M.D., FL, 2003 Medicine, Education: Research expertise: expertise: Clinical Professor Assistant M.D. Sathe, N. Meghana Fellow, Research and 2005-2006 Southwestern, Clinical Fellow, Southwestern, UT Gastroenterology, UT Nutrition, 2004-2007; Hepatology and 1999, Center, 2001-2004; SUNY, Resident, Medical Downstate Pediatrics, Brooklyn, Post-doctoral training: 1998 University M.B.B.S., of India, Mumbai, Education: disorders aerodigestive pain; expertise: Clinical Neurogastroenterology Director, Pediatric Professor Assistant Sanghavi, M.D. M. Rinarani University of South Alabama, Mobile, B.S., 1994; University of South Alabama 1994; Mobile, B.S., University of Alabama University South of Alabama, South University of Jordan, Amman, Faculty of Medicine, M.B.B.S., 1995 M.B.B.S., of Medicine, Faculty University of Jordan, Amman, School of Miller 1999; Wellesley B.A., University of MA, Miami, College, College, Medical G.S. 1994; H.S.C. Seth Mumbai, India, College, Jaihind Pediatric gastroenterology, inflammatory boweldisease gastroenterology, Pediatric inflammatory nutrition gastroenterology, Pediatric Eosinophilic esophagitis, inflammatory bowel disease, intestinal polyps intestinal disease, bowel inflammatory esophagitis, Eosinophilic Pediatric motility disorders, neurogastroenterology, chronic abdominal neurogastroenterology, disorders, chronic abdominal motility Pediatric Inflammatory boweldisease Inflammatory fibrosis, Cystic nutrition University of Arkansas for Medical Sciences, Little Rock, Resident, Little Sciences, for Medical University of Arkansas Seth G.S. Medical College, Bombay, College, Medical Intern, Pediatrics, India, G.S. Seth Al-Basheer Hospital, Ministry of Health, Amman, Jordan, Intern, Amman, of Health, Hospital, Ministry Al-Basheer UT 2003-2006; Southwestern/Children’s,UT Resident, Pediatrics, gastroesopageal reflux gastroesopageal disease Research interests: M.D. Cheng, Edaire Niemann-Pick C type Research interests: Assistant Professor, UTSouthwestern M.D. Ramirez, Charina oiohlseohgtsad Eosinophilis esophagitis and Gastroenterology 77 Transitioning adolescents with IBD to IBD to with adolescents Transitioning Inflammatory bowel disease,lymphocytic bowel Inflammatory Lillienne Yoon, M.D. Lillienne Yoon, interests: Research in IBD proteins COMMD care; adult Dyer Heintz, M.D. Dyer Heintz, interests: Research disease Chron’s and esophagitis Metabolic liver disease liver Metabolic Itching in colestasis Itching Eduardo Carlin, M.D. Carlin, Eduardo interests: Research Isabel Rojas, M.D. Rojas, Isabel interests: Research The nat ionaDallas with l satellite activity ly Legacy. In at environment, the Children’s at patient-centered thirteen gastroenterologyre cog nphysicians, eight gastroenterology practitioners, nurse three assistants, physician i and a child embedded psychologist z e d cl i n icin state-of-the-art the gastroenterology care children program, multidisciplinary, for with provide comprehensive a l prog rvirtually a m any gastrointestinal problem. liver or s of t he Div i sion of G a st ro enterolog y a re hou s e d at C h i ld ren’s Me d ic a l C enter Clinical Activities The second general area of active clinical research involves inflammation in the GI tract. Dr. Ashish Patel is leader leader is Patel Ashish Dr. tract. GI the in inflammation involves research clinical active of area general second The the the Trailblazer for of nutritional Collaborative pediatric algorithm management for Inflammatory development Andersen John is investigating eosinophilic Disease. treatments esophagitis. for new Dr. Bowel Dr. Norberto Rodriguez-Baez Norberto investigator Dr. is the principle NIH-supported study a national, multicenter, for our site at examining the fulminant causes for studies of group involves failure hepatic second in Rodriguez-Baez’s children. Dr. hepatitis chronic treatment of B and C. Funded gastroenterology research spans a wide range of important areas in and clinical both science basic investigation. both and basic clinical, the activeHepatology, most comprises Andrew Feranchak Dr. is recognized investigation. area of internationally elucidating to the his innovative for approaches mechanismsbasic regulating biliary and mechanisms secretion using bile formation inof vitro models well employing characterized hepatocyte and cholangiocyte cell lines. More specifically is his laboratory investigating regulatory the role of purinergic signaling in biliary secretion and bile formation. Feranchak’s is very research since it likely is pivotal, Dr. that disease liver therapeutic cholestatic interventions for a await understandingbasic the of mechanisms basic bile flow. of Research Activities Research Research Staff Research RNC Sharon Judy, Research Coordinator Research Associate Charles Kresge Research Coordinator RN, Shirley CCRC Montanye, 1st Year 1st 2nd Year Year 2nd Gastroenterology 78 of procedures. Fellows also are actively involved in research and scholarly activities throughout their three years of years three their throughout scholarly involvedof and activities actively research procedures. are in Fellows also performance the as well as services consulting inpatient,outpatient, and the in participation conferences active and didactic through fellows. The majority of educationfellowship is six has currently Education, Graduate Medical for overseentheCouncil Dr.by directed Accreditation by The Rodriguez-Baez, Norberto fellowship program, institutions. academic other students/residents from visiting residents and students, for medical clinic outpatient Gastroenterology the in offered also are conferences. Electives didactic and discussions small-group bedside teaching, patient care, direct afour-week in participate rotation. students Teachingresidents, asenior resident, medical isprovided and through venue for first-yearmain resident where to three two inpatient student education unit, and isarotation the in The Gastroenterology divisionPresentations/Teaching Activities is actively involved in the teaching of medical students, residents and fellows. The t(BTUSPFOUFSPMPHZQIZTJDJBOXIPJTPODBMMEBJMZUPUBLFDBMMT ages. of all children endoscopic cutting-edge procedures, endoscopic including cholangiopanereatography retrograde in specialized, tćFSBQFVUJD&OEPTDPQZQSPHSBN XIJDIJTPOFPGGFXFSUIBOQ Southwest comprehensive providing IBD. with for care children t4PVUIXFTUFSO$FOUFSGPS1FEJBUSJD*OĘBNNBUPSZ#PXFM%JTFBTF Southwest. the t*OUFTUJOBMSFIBCJMJUBUJPOQSPHSBN XIJDIJTPOFPGUIFMBSHFT none. to second results with States United the busiest in among the ranks that program aliver transplant and acute liver failure, and treatment t)FQBUPMPHZQSPHSBNXIJDIJTQSPEVDJOHJOUFSOBUJPOBMMZSFDPHOJ disorders. constipation digestive and vomiting, motility, abnormal pain, abdominal including t/FVSPHBTUSPFOUFSPMPHZQSPHSBNGPSUIFFWBMVBUJPOBOENBOBHFNF the: including programs special several through also providesdivision services The educator. enterostomal therapist/ an and work, apharmacist social life, child- dieticians, is supported by full-time apsychologist, two bowel colonic). and small antroduodenal, The entire program esophageal, (anorectal, procedures motility of range full (ERCP, enteroscopy endoscopy) capsule balloon and a and endoscopic endoscopy procedures, therapeutic but also medical assistants is capable of supporting not only routine two and of fivenurses laboratory staff gastroenterology The assistants. nurse-coordinators fivesix and medical of support the by four with nurse practitioners parallel seenin outpatients are to gastroenterologists, addition In atoneooylbrtr rcdrs 2,068 4,306 8,682 1,076 proceduresGastroenterology laboratory Outpatient center atChildren’s atLegacy New outpatientfacilitiesatChildren’s Dallaswith15examrooms andinfusionarea consultations Inpatient inpatient24-bed unit dedicated to gastroenterology and liver, including transplantation Statistics forabusyunit at Children’s: UJOUIFDPVOUSZBOEUIFPOMZQSPHSBNPGUIJTUZQFJO GSPNQIZTJDJBOT [FESFTFBSDIBOEDMJOJDBMTUVEJFTJOWJSBMIFQBUJUJT *#% XIJDIJTUIFPOMZDFOUFSJOUIF SPHSBNTJOUIF6OJUFE4UBUFTQFSGPSNJOH OUPGDIJMESFOXJUIBXJEFSBOHFPGEJTPSEFST 754 Gastroenterology 79 enting as a Gastric Outlet Obstruction,” NASPGHAN NASPGHAN Obstruction,” as a Gastric Outlet enting sease Research Conference, Scott & White and Texas Texas and & White Scott sease Conference, Research er Disease and Slows Down Neurodegeneration in the Neurodegeneration Down er Disease Slows and ds, Loma Linda Medical Center, CA, December 2010 Center, Lindads, Loma Medical trition Society 2010 Dallas, Dallas,trition TX, of August “Eosinophilic Esophagitis,” Pediatric Grand Roun Grand Pediatric Esophagitis,” “Eosinophilic Meeting, Annual NASPGHAN the Diagnosis,” Suggests History Hepatopathy: MA. “HIV S, Russo Walji-Virani Presentation) LA, October Orleans, 2010 (Poster New “Jaundice in Children after Two Years of Age,” 42nd Annual Kenneth C. Haltalin Pediatrics for the Practitioner, Practitioner, the for Pediatrics Haltalin Kenneth C. 42nd Annual Age,” of Years Two after in Children “Jaundice 2010 Dallas, TX, April Puerto Rico, Juan, San Hospital, Pediatric University Conference, Resident Pediatric in Children,” “Jaundice 2010 August Clinical of A Comparison Rodriguez-Baez S, Barth Atresia: B, N. “Biliary A, Megison C, Aqul Ramirez Presentation) LA, October Orleans, 2010 (Poster New Meeting, Annual NASPGHAN Experience,” Ramirez CM, Miller Am, Repa JJ, Turley SD, Dietschy JM. “Characterization and Treatment of NPC2 Disease NPC2 of in Treatment and JM. “Characterization Dietschy SD, Turley Am, Repa JJ, CM, Miller Ramirez Presentation) 2010 (Poster BC, May Vancouver, Societies Meeting, Academic Pediatric the Mouse,” Liv Ameliorates Administration Cyclodextrin “Weekly Crandall W, Kappelman M, Colletti RB, Denson L, Duffy L, Grunow J, Kim S, Leibowiz I, Pate, A, Schoen Pate, Kim S, I, J, Leibowiz L, Duffy Denson Grunow L, RB, M, Colletti Kappelman W, Crandall PIBDNet). (formerly Collaborative the ImprovedCareNow P and Cohen S, Margolis D, G, Miloy Tomer B, Digestive Colitis,” Ulcerative Pediatric for Collaborative Improvement in a Quality Outcomes “Improved 2010 LA, Orleans, May New Diseases Week, Selected Day, Research Senior Fellows’ Annual 1st Pediatrics, of Department C1 Mouse,” Type Pick Niemann 2010 May Speaker, JM. Dietschy SD, Turley AG, Weinberg DK, Burns AM, Repa JJ, A, Taylor Aqul B, Lui M, CM, Chang Ramirez Tucson, Type C Disease, Niemann-Pick on Scientific Conference Ara Parseghian Disedase“Pulmonary in NPC,” 2010 AZ, September Pres Gastroenteritis Eosinophilic Challenge: “Endoscopic “Writing Abstracts for Scientific Meetings: Presenting Your Ideas is Key to Your Academic Success,” Success,” Academic Your Key to Ideas is Your Presenting Meetings: Scientific for Abstracts “Writing 2010 FL, January Lauderdale, Fort Conference, Fellows Year First NASPGHAN, Di Digestive Formation,” Bile and Signaling “Purinergic “Overview of Gastroenterology,” UT Arlington, School of Nursing, February 2010 February Nursing, School of Arlington, UT “Overview Gastroenterology,” of 2010 Dallas, TX, March House, Our Children’s Baylor Rehabilitation,” “Intestinal Series, Lecture 2010 Dallas, TX, Practitioner April Nurse Parkland Syndrome,” Gut “Short Nu Rehabilitation,” Intestinal and “Nutrition TX, October 2010 Temple, Medicine, A&M College of 2010 FL, January Lauderdale, Fort Conference, Fellows Year First NASPGHAN GI Quiz Show, Moderator, Fort Conference, Fellows NASPGHAN/Nestle Table, Round Luncheon Basic in Research GI Careers Moderator, 2010 FL, January Lauderdale, Fibrosis Cystic American Disease, in CF Liver North 24th Annual Advances Co-chair, and Organizer October 2010 MD, Baltimore, Conference, October 2010 Website, “Single Balloon Enteroscopy” and “Clips,” NASPGHAN Therapeutic Endoscopy Pediatric “Hands-On” Courses, “Hands-On” Pediatric Endoscopy Therapeutic NASPGHAN “Clips,” and Balloon Enteroscopy” “Single 2010 IL, July Chicago, Post-Graduate Annual NASPGHAN Therapy,” Injection and Management Medical Bleed: GI Upper “The October IL, 2010 Course, Chicago, IL, Chicago, Course Learning Lunch, Post-Graduate Meeting, Annual NASPGHAN GI Bleeding,” “Upper October 2010 t Rinarani M. Sanghavi, M.D. t M.D. Michael A. Russo, t t t Norberto Rodriguez-Baez,Norberto M.D. CharinaRamirez, M. M.D. t t t Ashish S. Patel, M.D. S. Patel, Ashish t t t t Andrew P. Feranchak, M.D. Feranchak, P. Andrew Nandini Channabasappa, M.D. Channabasappa, Nandini t t t t t t t Bradley A. Barth, M.D. t t t Dr. Norberto Rodriguez-Baez Norberto Dr. is the program fellowship director as well as in the coordinator the education Division Responsibilities planning,Gastroenterology. include of and execution, evaluation all of and outpatient inpatient didacticrotations, curricular activities, of development activities, and medical methods assessment for students, pediatric and Mrs. fellows. residents, Erica McPhail is the administrave program the fellowship for and coordinator educationalits activities. training.nutrition elective has Division a The collaboration in created withelective This is dieticians Children’s. at to pediatric welloffered as residents to pediatricas adult Gastroenterologyand fellows. Gastroenterology 80 t t t t t t t t t M.D.Norberto Rodriguez-Baez, t M.D. M.Ramirez, Charina t t t t t t t t t t Ashish S.Patel, M.D. t t t Koorosh Kooros, M.D. t t t t t t Andrew P. Feranchak, M.D. t t Nandini Channabasappa, M.D. t t t t M.D. A.Barth, Bradley t t t t t t t t t John M.D. M.Andersen, Major Administrative Responsibilities orLeadership t Meghana N.Sathe, M.D. Chair, Educational Committee Pediatric Gastroenterology Division Member, Presentation and Publication Committee for Pediatric the Acute Liver Failure Study Moderator, Pediatric –DDW Session 2010 Member, NASPGHAN Annual Meeting Planning Committee Chair, Organizing Committee – International Reception at 2010NASPGHAN Annual Meeting & Moderator,Co-Chair LASPGHAN Concurrent at Session 2010NASPGHAN the Annual Meeting Chair, International Committee NASPGHAN Member, Organizing Committee, LASPGHAN Conference at NASPGHAN the Annual Meeting Director, Pediatric Fellowship Program, Gastroenterology and Nutrition, Children’s Co-founder and Co-Organizer, Teen IBDGroup, Children’s Ad Hoc Reviewer, IBDJournal, Pediatrics, JPGN Ad Hoc Reviewer, InflammatoryBowel Diseases Core Interviewer, UTSouthwestern Program Residency Core Interviewer, UTSouthwestern Medical School Core Interviewer, University Emory Physician Champion, Gastroenterology Patient Education, Children’s Physician Parent Lead, Support Group for Pediatric InflammatoryBowel Children’s Disease, Vice Chair, Crohn’s and Colitis Foundation of America Medical Director, CCFA Camp (acamp Oasis for children with inflammatorybowel disease) Director, InflammatoryCenter,Bowel Disease Children’s Investigator, Autism Treatment Network Member, Task Seals Easter Force Pract Establish Best Development of Pediatric EUSProgram, Children’s Member, Cystic Fibrosis Foundation TherapeuticsData Safety MonitoringBoard Member, of Pediatric Society Research Fellow’s and Basic ClinicAward Committee Selection Member, Infant Nutrition Advisory Group, Cystic Fibrosis Foundation Member, Training Committee, NASPGHAN Reviewer, Fellow Senior Research Day Abstract Review, Department of Pediatrics, UTSouthwestern Chair, ClinicalResearch Advisory Committee, Grant Committee, Review Children’s Member, Operating Room Committee, Children’s Director, Intestinal Rehabilitation Program, Children’s Core Interviewer, Resident Applications, Children’s Ad Hoc Reviewer, Journal of Pediatrics Member, Endoscopy Procedures Committee, NASPGHAN Director, Endoscopy Lab, Children’s Ad Hoc Reviewer, Journal Pediatric Gastroenterology and Nutrition Ad Hoc Reviewer, Pediatric Nephrology Member, Development Committee, Children’s at Legacy Member, Ambulatory Pre-Arrival Access to MDCommittee, Children’s Member, Process Improvement Steering Committee, Children’s Member, Organ Solid Transplant Steering Committee, Children’s Member, Pediatric Practice Committee, UTSouthwestern Medical Director, Liver and Intestinal Transplant, Children’s Director, Division of Pediatric Gastroenterology Nutrition Annual Meeting, Vegas, Las NV, February 2010(Poster Presentation) Following AntirefluxCenter A Single Experience,” Surgery: Society for American Parenteral and Enteral J. M,Andersen Sathe M,Benser M,Carrillo “Diagnosis ices for GIDiagnosis&Management of Autistic Children and Management of Dumping Syndrome inChildren Gastroenterology 81 lic Gastrointestinal Disorders Support Group Support Disorders lic Gastrointestinal logy, Consumer’s Research Council of America Council of Research Consumer’s logy, D Magazine D Magazine D Magazine D Magazine Parent’s Magazine Parent’s Texas Monthly Texas Best Pediatricians in Dallas, Best Pediatricians in Dallas, Best Pediatricians Strong Star Super Doctors, Doctors, Super Best Doctors in America in Dallas, Best Pediatricians Gastroentero Pediatric Pediatricians, Top America’s Best Doctors in America in Dallas, Best Pediatricians Associate Director, Pediatric Fellowship Program, Gastroenterology and Nutrition, Children’s Medical Center Medical Children’s Nutrition, and Gastroenterology Program, Fellowship Pediatric Director, Associate Board Advisory Medical Alliance Alagille Syndrome Member, Check-In Staff Medical Colitis and Oasis, Crohns Camp Member, Committee Development Center Disorders Feeding Chairman, Director, Pediatric Gastroenterology Motility Lab, Children’s Lab, Motility Gastroenterology Pediatric Director, Children’s Center, Aerodigestive Pediatric Co-director, Clinic, Children’s Pain Abdominal Chronic Co-director, Clinics, Children’s Southlake Clinical Liaison, (NASPGHAN), Nutrition and Hepatology Gastroenterology, Society Pediatric American for North Chair, India in Mumbai, Mission Medical Activities, Civic Member, Best Doctors in America Member, Core Interviewer – Pediatric Residency Program – UT Southwestern Residency Program – Pediatric Interviewer Core Member, Southwestern UT Rotation, Gastroenterology Clerkship Pediatric Student Coordinator, UT Southwestern – Students Medical – Minority Advisor UT Southwestern in Pediatrics, Interested Students Medical Mentor, Legacy at Children’s Gastroenterology, Pediatric Director, group) support esophagitis eosinophilic (an Hope of Hands Medical Dallas Metroplex Liaison, Eosinophi Hope”: of Liaison,“Hands Lead Physician Professional Consultant, Consultant, Professional t Norberto Rodriguez-Baez,Norberto M.D. t M.D. Michael A. Russo, Koorosh Kooros, M.D. Kooros, Koorosh t Andrew P. Feranchak, M.D. Feranchak, P. Andrew t Bradley A. Barth, M.D. t t John M. Andersen, M.D. John t Awards and HonorsAwards t t M. Gaith S. Semrin, M.D. t Meghana N. Sathe, M.D. N. Sathe, Meghana t t t Rinarani M. Sanghavi, M.D. t t t t t t t t t t M.D. MichaelRusso, A. t t t t t Gastroenterology 82 General Pediatrics , 83 Patient , Academic Pediatrics , Glenn Flores, M.D. Glenn Flores, Director, General Pediatrics Director, , recognition in the Guide . Our two Academic General Pediatrics Contemporary Pediatrics , , recognitionPediatric as The Best D Magazine MD Advisor MD , Texas Monthly Texas on hason recognized national in leadership research, health General Pediatrics General Journal of Developmental and Behavioral Pediatrics of DevelopmentalJournal Behavioral and and and Journal of Allergy and Clinical Immunology , Education and Counseling Glenn Flores, M.D., F.A.A.P., Professor of Pediatrics, of Clinical Professor Sciences, and Public F.A.A.P., Glenn M.D., Flores, Health, and the Judith and Charles Ginsburg Chair in Pediatrics, is the Director theof General Division of Pediatrics and the the Director of Academic General Pediatrics Fellowship Program. Flores Dr. graduated with high honors from Cambridge,Harvard Massachusetts, University, in his and 1984, medical received California,degree of from the University After residency a San in Francisco, 1989. Hospital/ Cornell he 1992, to Medicalin from pediatrics 1989 Center York New at is a member He 1995. to was an Clinical from 1993 RWJ University Yale Scholar at theof editorial the board of Journal Health of and Underserved, the Care Poor for and previously served the on editorial Academic Pediatrics. board of is Chair He of the Research Committee the of Pediatric Academic of Association, and a member the United States Preventive Services Force, Task National Advisory Committee of Amos Program, Medical Johnson the Faculty National Robert Wood Development Advisory Committee of the Robert Johnson Wood Foundation Aligning Forces Qualityfor Program, Advisory National Committee subcommittee Children’s on Faculty Since theSince last annual report, articles, division faculty 11 including articles published in Barrios Unidos Community Clinic is a Federally Qualified Health Center (FQHC) that is accredited by The Joint Joint The by accredited is that (FQHC) Center Health Qualified Federally a is Clinic A partnership was established with Los Barrios Community Pediatric newest Unidos Clinic as UT Southwestern’s Community Continuity Clinic and an site additional clinical setting our bilingual where faculty Unidos care children. provide to Los Barrios healthCommission. clinic The toworks qualityimprove and providingof by life medical a for individuals home and predominantlyfamilies. Spanish primary serves It a low-income, language in population Dallas. and residents Four two care attending Los at provided Barrios physicians in 2010. health and well-being of vulnerable individuals, children, and families by integrating legal services into the medical medical the into Division The established Medical-Legal services the which Medicalthe aims legal Partnershipto improve Center, at Children’s integrating by families and children, individuals, vulnerable of well-being and health setting. In 2010, Division faculty supervisedIn 2010, the pediatric 9,800 in seen by patients care the over residents of Resident Continuity Clinic. Over 6,000 seen in additional our specialized were patients clinics, and our attending physicians 2,000cared over for hospitalized children the teaching on inpatient services, while providing outstanding teaching to pediatric and UT residents Southwestern medical students. Division faculty States Preventive and the awards, to including United honors appointment garnered numerous grant from an theInstitutes National Services R01 Health Force, of (NIH) Eunice Shriver Task National Kennedy Social Award Justice Rodríguez-Trías Helen the 2010 Institute Child (NICHD), of Health and Human Development thefrom Advocacy American the from award Public Health Children’s Association, the the Child of Year Advocate by Doctor Collin Super of Center recognition as a Texas County, policy and advocacy regarding racial and ethnic disparities in child health andhealthcare, and in improving access andto quality underserved care children. of for of populations Pediatric Academic abstracts SocietiesPediatrics meetings, presented the fellows at 2010 including a platform and threepresentation presentations. poster The mission of of of Pediatrics DivisionGeneral The healththe mission the to is well-being improve of children and through excellence in clinical care, teaching, Divisi The research, and advocacy. Specialists in Dallas 2010 (for threeSpecialists faculty) and Best in Doctors in (for Dallas Dallas by 2010 Pediatricians Consumer by Research in America, Top thenomination a to America’s to Gamma Alpha of Chapter from the Classes 2012 Award of MedicalUT a Outstanding Southwestern Society, Alpha Honor Omega Teacher a UT Pre-Clinical Southwestern inand Clinical 2013, Teaching selection from the Class2012, Medicine of Award as a finalist in Award, Healththe UT in Southwestern Innovation educationalan Education Science grant from Small Health Grants Program, Sciences Foundation’s Texas the of University a UT Southwestern Faculty Teaching a UT from the Class Award a UT 2010, in of Southwestern Clerkship Pediatric Core Teaching Award Residency, ClinicalSouthwestern a grant Researchand of Evaluation Scholars from the Award, Program the Development for Community Model Initiatives election the to in American Dallas Society (PDEMCHID), Clinical of and Nutrition, a grantCommunity from the Child American to Access Health Pediatrics. of Academy (CATCH) Journal of Immunology General Pediatrics 84 papers that address uninsured children and racial/ethnic and linguistic disparities in children’s health and healthcare. children’s and in health disparities linguistic and racial/ethnic and children uninsured address papers that of topics in such journals as as journals such in topics of book chapters and He Association. published on has 123 avariety Public Health Award articles American from the Brock 2010 Award and ContributionsRichard to Pediatrics, for Helen Distinguished Rodríguez-Trías Justice Social and Achievement Millie Advocacy, Award Application of the 2008 Health Epidemiologic in to Child Information Workshop. Street Academy Sesame Outstanding of the Pediatrics and Association, American He received 2006 the Medical Centers National Association, Hispanic for Control Prevention, and Disease Medical NICHD, American member U.S. for Surgeon the committee General, the advisory or aconsultant national as He served Commission. has Pelosi. Houseof for Nancy the Services Texas Human He the and Committee isamember Frew of Health the Advisory on America’s Summit National convened at the Children speaker by invited Speaker Dr. an previously Floresalso was for U.S. House the of Representatives’ disparities Ways on testimony Committee. health Means and written invited Improvement Health andHispanic the has provided and Act, the in Senatehealth United Latino States on testified has Briefing, Implementation Research provided has aCongressional Guide, Services Language Care Health Services Human and of Health for Panel Department the amember Expert as of the served He also has Measures. Quality Care Health and Health on Pediatric Committee of Medicine Institute the and Academy of Pediatrics, American California in Healthcare of the on Research (NICHQ), Pediatric Children’s Committee for National Initiative Children’sof Quality the Healthcare Improving for Programs Innovative Identifying on Committee Advisory National Quality, and Research Agency of for the Healthcare Programs for CHIP Measures and Medicaid Quality Healthcare 1994; Fellow, 1994-1997 Emergency Medicine, Pediatric Post-doctoral training: University,Reserve OH, M.D., Cleveland, 1991 1985;M.S., School Mount New of York, Medicine, Sinai NY, Ph.D., 1987; Western Case Education: expertise: Clinical Professor Assistant Clinical Susan Dibs, M.D. 2008-2010 Fellow,Southwestern, Pediatrics, General Academic Post-doctoral training: Education: prevention expertise: Clinical/research Professor Assistant M.D. Dakil, Suzanne Fellow, 2002-2004 Neglect, and Abuse Child 1998–2001;Pediatrics, Resident, 2001-2002; Chief Children’s PA, of Hospital Philadelphia, Post-doctoral training: M.D., 1998 Education: pediatrics expertise Clinical/research REACH of Director Clinical and Professor Associate Matthew J. Cox, M.D. 2000-2003 City, Resident, Pediatrics, Oklahoma Oklahoma, Post-doctoral training: City, M.D., Oklahoma ofCollege Medicine, 2000 Education: expertise: Clinical Professor Assistant Amy M.D. Barton, JAMA Emory University, Atlanta, GA, B.S., 2001; University of Louisville, KY, University, 2001; Emory M.D., GA,B.S., 2005 University Atlanta, of Louisville, 1996; University B.A., of Oklahoma Falls, Iowa, University of Cedar Northern University of California, Los Angeles, B.S., 1981; B.S., Angeles, Los University PA, of University California, of Pittsburgh, Texas University, A&M School at 1993; Houston, Station, College B.S., Medical UT , the , the New England Journal ofMedicine Journal New England International adoption medicine adoption International pediatrics General University of Oklahoma Health Sciences Center/Children’s Sciences Health University of Oklahoma of Hospital Children’s Hospital of Philadelphia, PA,Children’s of 1992- Hospital Philadelphia, Resident, Pediatrics, UT 2005-2008; Southwestern/Children’s,UT Resident, Pediatrics, Resident,Vanderbilt TN, Center, University Medical Nashville, : Physical abuse, sexual child abuse, neglect, inpatient general neglect, abuse, child sexual : Physical abuse, General pediatrics, risk factors for child abuse and child abuse abuse child and factors abuse for risk child pediatrics, General , Pediatrics , and the the , and Lancet , including many many , including General Pediatrics 85 General pediatrics, health care and access health to care of general and sexual Adolescent health issues, racial/ethnic health General pediatrics, guidance, anticipatory injury and poison Louisiana Orleans, New Resident, Health State Center, Science Baylor Albany Medical Intern 1998-2001; and Resident, College, NY, Rush University Medical Center, Chicago, IL, Medical Rush University Pediatrics, Resident, Center, Arkansas of University Medical for Sciences, Little Resident, Rock, Ramathibodi Hospital, Rotating Intern, Pediatrics, 1973-1974; Ramathibodi Rotating Hospital, Intern, Pediatrics, 1973-1974; Pediatrics, Resident, 2004-2007; Chief UT Southwestern/Children’s, General pediatrics, dermatology, asthma General pediatrics General pediatrics Louisiana State University, Baton Rouge, B.S., 2000; Rouge, Baton UT Louisiana Medical University, State Branch at Albany B.A., 1992; Medical M.D., NY, College, NY, York, New Cornell University, Texas A&M University, College Station, B.S., 1983, UT Medical B.S., College Station, 1983, Branch at A&M University, Texas Creighton University, Omaha, NE, University, Rush University, B.A., Creighton cum 2001; laude, Texas A&M University, College Station, B.S., College Station, 2000; A&M University, UT Health at Center Texas Science Mahidol University, Bangkok, Thailand, B.S., 1971; Mahidol University, Bangkok,University, Thailand, Mahidol Mahidol University, 1971; B.S., May Lau, M.D., M.P.H. M.D., Lau, May Assistant Professor Clinical/research expertise: underserved children Education: 2005 M.D., Galveston, training:Post-doctoral Pediatrics, 2005-2008; Pediatrics, Chief Resident, 2008-2009 disparities Education: 2004 M.P.H., UT Health1998; Houston, at Center Science training:Post-doctoral Medicine, 2001- Adolescent Fellow, Houston, Hospital, Children’s Medicine/Texas College of 2004; Maternal and Child Health Health Bureau, and Resources Services Administration, Health, Leadership Education in 2001-2004 Adolescent Fellow, Karen Y. Latour, M.D. Latour, Y. Karen Assistant Professor Clinical/research expertise: 2006-2008; 2008-2009 ChiefResident, prevention, resident education in continuity clinic Education: 1994 M.P.H., UT Health Houston, at Center Science 1987; Galveston, M.D., training:Post-doctoral Medicine, College of Baylor Pediatrics, Chief Resident, 1990-1991; Pediatrics, 1987-1990; Academic General TX, Pediatrics, Fellow, Houston, 1991-1994 Nancy R. Kelly, M.D., M.P.H. Nancy R. Kelly, Professor Associate Clinical/research expertise: Education: Chicago, IL, 2005 M.D., training:Post-doctoral Assistant Professor Clinical expertise: Shelby Joseph, M.D. Shelby Assistant Professor Clinicalexpertise: Education: 2004 M.D., Houston, training:Post-doctoral Lauren Gore,Lauren M.D. UT Southwestern/Children’s, Resident, 1974-1977; UT Southwestern, Fellow, Ambulatory UT Southwestern, Fellow, 1974-1977; Resident, UT Southwestern/Children’s, Pediatrics, 1977-1979 Pediatrics,Resident, 2007-2008 Vanthaya N. Gan, M.D. N. Gan, Vanthaya Professor Clinical expertise: Education: Ramathibodi Bangkok, Hospital, Thailand,1973 M.D., training:Post-doctoral General Pediatrics 86 Post-doctoral training: Education: expertise: Clinical Associate Professor Lee,M.D. Michael Southwestern, HIV Clinical Fellow, Vaalwater, June-September Clinical 2010Southwestern, HIV Africa, South Post-doctoral training: Antonio,Center at M.D., San 2007 Education: preventative exposure/infection medicine, HIV expertise: Clinical/research Instructor Scheideman,M.D. Erin E. 1978-1981; Fellow, Adolescent 1981-1982 Medicine, Post-doctoral training: School, M.D., Boston, MA, 1978 Education: education and delivery Research interests: Professor Assistant Carol P. Podolsky, M.D. Development, Faculty 1998-2000 HRSA 1995-1997;Pediatrics, 1997-1998; Resident, Chief Pediatrics, Center, Medical Maricopa Fellow, Post-doctoral training: 2001 Tucson, Health, Public in School M.D., of Graduate M.P.H., Program Medicine, 1995; Arizona Education: expertise: Clinical/research Professor Assistant Anu Partap, N. M.P.H. M.D., 2003-2005 Resident, Pediatrics, Scheme, 2001-2002; School, Hasbro Children’s Brown Medical Hospital, Providence, RI, Training Pediatric International London, England, ChildHealth, and ofCollege Pediatrics School, University of Fellow, Sydney,Clinical Neonatology, Australia, Royal 1998-2000; Post-doctoral training: M.D.,India, 1994 Education: expertise: Clinical/research Professor Assistant M.D. Vineeta Mittal, 2006-2009 APA Program, Scholars Educational Post-doctoral training: Education: expertise: Clinical/research of Student ProfessorAssociate Affairs Dean Associate and P.Angela M.D. Mihalic, Vanderbilt University, Nashville, TN, B.A., cum laude, 2003; UT Health Science Vanderbilt Health UT laude, 2003; University, cum B.A., TN, Nashville, City, 1992; B.A., University Kansas of University Missouri-Kansas of Missouri, Xavier’s St. Bombay College, University, 1988; H.S.C., Bombay India, University, Southwestern, of M.D., College UT Pharmacy, 1990; Austin B.S., 1995 UT Cornell University,Cornell New York, honors, NY, 1974; with Medical B.A., Harvard Baylor University, Waco, 1987-1991, TX, Southwestern, M.D., UT 1995 General pediatrics General Adolescent medicine, childhood immunization, school-based health care care school-based health Adolescent immunization, childhood medicine, UT Southwestern/Children’s, Resident, Pediatrics, 1995-1998 Southwestern/Children’s, UT Resident, Pediatrics, UT Southwestern/Children’s, Resident, Pediatrics, 2007-2010; Southwestern/Children’s, UT Resident, Pediatrics, UT Center/Phoenix Children’s Medical Hospital, Resident, Maricopa Southwestern/Children’s, 1995-1998; UT Resident, Pediatrics, PAS/ Children’s Center, Medical Hospital Resident, Boston, Pediatrics, MA, Bombay University, 1994-1997; Resident, Pediatrics, India, Canberra International medicine and global health, public health, general general public health, health, global and medicine International care family-centered pediatrics, General General pediatrics, child abuse and neglect abuse and child pediatrics, General resident student and education medical pediatrics, General General Pediatrics 87 Christina Sakai, M.D. Christina Sakai, Position: Current Pediatrics Behavioral Developmental Medical New England Tufts Fellowship, Center Research Interests: in transition healthcare care, foster Kinship youth care foster , 1998; UT Health, 1998; at Center Science cum laude cum Dietary and behavioral obesity interventions, health disparities in General pediatrics, Latino child health, violence youth University of North of University Carolina Hospitals, Hill, Chapel Resident, Intern UT and Pediatrics, Resident, Southwestern/Children’s, 2004- Duke Durham, MedicalUniversity Internal NC, Resident, Center, University of California, of University Los Angeles, Pediatrics, Resident, Parkland Memorial Dallas, Hospital, TX, Rotating 1959-1960; Intern, Adolescent andcare adult young Adolescent medicine, child maltreatment Adolescent General pediatric consultation Suzanne Roper Dakil, Roper M.D. Suzanne Position: Current General Pediatrics, Professor, Assistant UT Southwestern Research Interests: neglect, socio-demographic and Child abuse children of characteristics geographic and development head trauma, abusive with efforts guide risk and at families identify to tools of prevention Princeton University, NJ, A.B. NJ, University, Princeton Drew University, Madison, NJ, B.A., 2000; Medicine and of University, DentistryDrew University of Hendrix College, Conway, AR, B.A., 2000; Hendrix College, Conway, UT Houston, Health at Center Science Loyola Marymount University, Los Angeles, Hopkins Marymount CA, B.S., Johns Loyola 1999; University, Tulane University, New Orleans, LA, B.S., 1956; Tulane University School of of School University Orleans, New LA, Tulane B.S., 1956; University, Tulane Post-doctoral Fellows Fellows Post-doctoral 2010 Completed June Laura Wolovits, M.D. Wolovits, Laura Assistant Professor Clinical expertise: Education: Education: 2003 M.D., Houston, training:Post-doctoral Education: 2004 M.D., training:Post-doctoral Jennifer Walsh, M.D. Walsh, Jennifer Pediatrics and Internal MedicineAssistant Professor, Clinical expertise: Internal Medicine and Pediatrics, 2003-2007 Oakland, and Hospital 2006; Research Center, Pediatrics, Children’s CA, Resident, 2006-2007 Instructor, PediatricsInstructor, and Internal Medicine Clinical/research expertise: Christy Turer, M.D., M.H.S. Turer, Christy overweight andoverweight obese patients Education: Medical 2004; Durham, Baltimore, M.D., M.H.S., School, Duke MD, 2010 University, training:Post-doctoral Medicine and Pediatrics, 2004-2008 Joel B. Steinberg, M.D. Joel B. Steinberg, Professor College UT at Fashena Southwestern Master, Clinicalexpertise: Education: Medicine, Orleans, 1959 New LA, M.D., training:Post-doctoral prevention, Latino childprevention, health, racial/ethnic health disparities Education: California of 2003; University Medical Jersey Newark, M.D., – New School School, Jersey New Public Health,of Los Angeles, M.S.H.S., 2008 training:Post-doctoral Community Health & AdvocacyTraining Program, 2003-2006; California, of University Los Clinical Johnson Robert Wood Scholars Program, 2006-2009Angeles, Fellow, Medicine, of Charity School University Louisiana, Hospital of Tulane Pediatrics, Resident, Pediatrics, Chief Resident, 1962 1960-1962, Rashmi Shetgiri, M.D., Shetgiri, M.S.H.S.Rashmi Assistant Professor Clinical/research expertise: General Pediatrics 88 Adoption Medicine Program Medicine Adoption United One the of the afew only States, in dozen AYA to improve seeks adolescent Clinic health. the research, and education delivery, healthcare Through clinics. healthcare and physicians community from referrals for patients 11services to 21 welcomes old, and years Adult (AYA) Clinic in adolescent and sports medicine, the the adolescent medicine, in sports and by training interestStaffed andphysicians who have special Clinic. Unidos Barrios at Community and Los clinics specialized provide nine and consultation outpatient in and care service inpatientthe teaching both members staff faculty at outpatient Children’sand Center. care Medical Division The Division of General Pediatrics provides both inpatient Activities Clinical for care adolescents young adults. and transitional and students, medical of teenpregnancy, for of interventions poison use educational residents control care, and centers, family-centered prevention teendating, workforce prevention research, diversity,pediatric of qualitative youth bullying, violence and health, on child its impact and poverty obesity, competency, health, oral asthma, cultural healthcare, in issues language disparities, patient safety, of racial/ethnic care, quality policy, to healthcare, access health services, health pediatric including of domains, encompass variety Pediatrics awide of Division General the in activities Research Research Activities Bridon, Coordinator Senior Program Christina Walker,Candice Ph.D., Coordinator Study Research III Ph.D., Consultant Hua Lin, Biostatistical ResearchClinical Staff 1st Year The The needs. physical, developmental social-emotional follow-upand special and with screenings, for care children health before evaluations adoption, initial medical for including doctors who them, care community the and parents, their children, adopted internationally assist to advice and care systems, and the REACH Team to optimize each child’s health, healthcare, safety, and well-being. well-being. safety, and healthcare, health, child’s each Team REACH the and to optimize systems, Pat Glazier, Mary foster court work foster and CPS, parents, agencies, closely with Arthur PNPs Sandra and Sakai, out-of-home in to 19 old years living Christina and infancy Partap Anu Drs. placement neglect. and abuse due to child The The County. Dallas in foster care in for children services medical care primary and screenings, developmental and physical pre-adoption exams, placement provide they where Clinic, Care Foster the in care for children practitioners nurse SupportedREACH pediatric by physicians, the Program. through offered are services agencies social and of local state and avariety follow-up Medical with abuse. child networking and suspected of cases in consultations emergency inpatient department and as well prevention as treatment, and diagnosis, abuse Referral Evaluation of At Risk Children (REACH) Program Foster Care Clinic Care Foster sexual assaul sexual forensics exams foster care and kinship care; utility of children, including are who those in healthcare of abused and neglected education; improving health the and Childabuse prevention through Interests: Research M.D. Lang, Cathleen provides primary and specialty care care specialty and provides primary provides placement exams, medical homes, and pre-adoption homes, and from for physicals medical provides children placement exams, offerscomprehensive medical Adolescent Young Adolescent International International
otrCr 1,963 838 96 9,870 12 15,985 1,948 &Consultation Diagnostic Pediatric Medicine Adoption International Teaching Student Medical 1,258REACH Adolescent Young Adult (AYA) Care Foster Continuity Resident provides outpatient medical evaluations for child- for evaluations medical outpatient provides 1st Annual Senior Fellows Research Day Research Fellows Senior 1st Annual 2010 Patient Visits Clinic Dr. Suzanne Dakil Dr. Suzanne
Visits General Pediatrics 89 , providing comprehensive care , providing comprehensive s, Children’s Hospital of Oklahoma, Oklahoma City, City, Oklahoma Oklahoma, of Hospital s, Children’s Program Grand Rounds, Children’s Medical Center, Center, Medical Children’s Rounds, Grand Program Program at Children’s Medical Center,” Hands-On Hands-On Center,” Medical Children’s at Program Resident Continuity Clinic Continuity Resident Children’s Advocacy Center Crimes Against Children Children Crimes Against Center Advocacy Children’s e US,” Pediatric Academic Societies Annual Meeting, Societies Meeting, Annual Academic Pediatric e US,” cares patients for Annual Kenneth C. Haltalin Pediatrics for the Practitioner Seminar, Seminar, the Practitioner for Pediatrics C. Haltalin Kenneth Annual nd evaluates selected acute, evaluates acute nonemergency patients. Division physicians supervise pediatric Medical Student Teaching Clinic Teaching Student Medical Pediatric Diagnostic and Consultation Clinic Acute Care Clinic (First Care) (First Clinic Care Acute “Child Abuse and Neglect: The Medical Perspective,” Lecture for Law Students,Southern Methodist University, University, Methodist Students,Southern for Law Lecture Perspective,” Medical The Neglect: and Abuse “Child Dallas, TX, 2010 February Law, Dedman School of Does Much How Risk and at Who’s in US Children: Poisoning for G. “Hospitalizations NR, Lin H, Flores Kelly Societies’ Academic Pediatric Initiative,” Oral Health N. “Resident Kelly D, S, Troendle Cost?”it Troendle and Presentations) 2010 (Poster BC, May Vancouver, Meeting, Annual Injury of Knowledge Resident Pediatric of “Survey P. Hicks N, Okada P, R, S, Kelly Scott Devdas G, Weibe April 2010 April and Child Maltreatment” Risk for High at Communities Indentifying for Tool An Innovative “Geo-Mapping: in th in Child Neglect Disparities Ethnic “Racial and Dallas Abuse,” Child Physical of Evaluation “Medical Receiving Officers Peace for Lecture Children,” Protect to Know to Need You What Neglect: and Abuse “Child February 2010 TX, Desoto, PoliceDepartment, Desoto License, Officers Peace Intermediate “Failure to Thrive: The Bare Bones” and “What Would You Do: Genital Injuries in Children,” Dallas Children’s Dallas Children’s in Children,” Injuries You Do: Genital Would “What and Bones” Bare The Thrive: to “Failure 2010 Dallas, TX, Conference, August Children Crimes Against Center Advocacy Emergency Services Pediatric Network Children,” in Young Injuries Traumatic Do: Suspicious You Would “What Dallas, TX,Conference, December 2010 Societies Annual Academic Pediatric Reabuse,” for Risk Factors System: ”Recidivism in the US Child Welfare 2010 BC, May Vancouver, Meeting, November 2010 November 42 Role,” Pediatrician’s The Abuse: ”Child Trauma Cases,” in Child Abuse Controversies “Medical REACH Children: At-Risk of Evaluation and “Referral Presentations) (Poster 2010 BC, May Vancouver, 2010 Dallas, TX,Conference, August “Child Sexual Abuse Quandaries,” Pediatric Grand Round Grand Pediatric Quandaries,” Sexual Abuse “Child Medical Children’s Conference, Practitioner Advanced Children,” Protecting and Identifying Abuse: “Child 2010 February Center, Society Managers of the Case Worth Chapter Dallas-Fort Provider,” Medical of the The Role Children: “Battered 2010 TX, CMSA), Arlington, March America (DFW of “Disparities in Immigrant Latino Children’s Health and Healthcare: How We Can Level the Playing Field,” Field,” Level Can the Playing We How Healthcare: and Health Children’s Latino Immigrant in “Disparities Schools & Serving Professions the Hispanic Health by Sponsored Health, Immigrant Latino on Conference CA, 2010 Alto, Palo Excellence, of Center Hispanic Stanford Grand Care,” in Health Quality and Communication, Barriers, Interpreters, Language in Translation: “Lost 2010 Bethesda, MD, Health, of Institutes National Rounds, 2010 Dallas, July Address, Keynote Healthcare Richardson, TX, April 2010 TX, April Richardson, The residents and support educationalresidents objectives through care, patient informal lectures, and teaching conferences. The referred by primary-care physicians and specialists. Division faculty evaluations and diagnoses and patients make of comprehensive conduct treatment and referrals for recommendations primary-care back to and specialists.physicians Nancy R. Kelly, M.D., M.P.H. M.D., Nancy R. Kelly, Dakil,Suzanne M.D. Matthew J. Cox, M.D. Cox, J. Matthew Amy Barton, M.D. M.D. Barton, Amy Presentations/Teaching Activities Presentations/Teaching F.A.A.P M.D., Glenn Flores, Pediatric residents receive training receive Pediatric residents in primary care in the component of their pediatric clerkship. It is staffed both by division division by both staffed is It clerkship. pediatric their while patients providing outstandingnonemergency supervised learning of medicalexperiences for students rotating through the outpatient component faculty and clinical faculty pediatricians the from community. The under the supervision faculty Division of both to well and chronically ill children. clinic The alsois settingthe for many clinical studies. This state-of-the-art Clinic includes technologies that maximize care patients. and for improve residents the educational experience for General Pediatrics 90 Vineeta Mittal, M.D. M.D.Angela Mihalic, May M.D. Lau, UT Southwestern, November 2010 “Implementing Successful Family-Centered Rounds,” Pediatric Academic Meeting, Society Vancouver, May BC, 2010 “Impact of Family-Centered Rounds on Medical Education,” Facilitator for Family-centered the Care SIG, Pediatric Academic Meeting, Society Vancouver, May BC, 2010 “Navigating Ship the AFaculty Successfully: Development Program to Train Faculty to Conduct Efficient FCRs,” Presentation) Outcomes? AQualitative Study,” Pediatric Academic Meeting, Society Vancouver, May BC, 2010(Poster Family-Centered Rounds Enhance Resident’s Clinical Safety, Outcomes, and Trainee Education? AQualitative “Do Family-Centered Rounds Improve Parent Satisfaction, Communication, Coordination of Care, Patient Hospital Medicine Meeting, Minneapolis, July 2010 Safety, Outcomes, and Trainee Education? AQualitative St “Do Family-Centered Rounds Improve Parent Satisfaction, Communication, Coordination of Care, Patient Faculty Retreat, UTSouthwestern, November 2010 “Effectively Teachingthe Millennial-Bridgingthe Gap Seton Medical Center, November 2010 “Millennials in Medicine- Bridging Gap the inMedical Educ Celebration of Day of Children’s Americas, the Medical Center, 2010 October “Becoming Linguistically Competent and Interpreter Workshop,” First Annual Language Access Fair in Facilitation,” UTSouthwestern Resident asEffective Teacher Workshop, 2010 October “Resident as Effective Teacher Introduction/AdultLearning Theory,” and“Communication Styles and Effective Southwestern, August 2010 “Culture and Medicine,” Physician Awareness and Ethics, Department of Neurology Resident UT Lecture Series, Southwestern, April 2010 “Effectively Teachingthe Millennial- theBridging Gap in Education,”Medical Effective UT Series, Teacher University Health Center Paul Science Foster of School Medicine, Paso, El February 2010 TX, “Millennials in Medicine- Bridging Gap the inMedical Educ of Texas Southwestern Medical Center. January, 2010. “How to Create aTeaching Portfolio,” New Faculty Orientation Division Series, of Pediatrics, General University Presentations) American PublicDisparities?” Health Association Annual Meeting, Denver, CO, November 2010(Poster Spoken at Home and Health and Healthcare Disparities inUSAdolescents: Has Tincture the of Time Reduced Has Anything Changed Years?“ the Over and Lau M,AvilaLanguage H,Flores Lin Primary R, G.“The Lau M,Avila H,Flores Lin R, G.“Racial/Ethnic Disparities Health inthe and Healthcare of USAdolescents: CO, November 2010 Vaccination and its Recommendation US,” inthe American H,FloresLau M,Lin G.“Adolescent Females and Human the Papillomavirus Vaccine –Factors Associated with AcademyHealthDisparities?” Annual Research Meeting, MA,June Boston, 2010(Poster Presentations) Spoken at Home and Health and Healthcare Disparities inUSAdolescents: Has Tincture the of Time Reduced Has Anything Changed Years?” the Over and Lau M,AvilaLanguage H,Flores Lin Primary R, G.“The Lau M,Avila H,Flores Lin R, G.“Racial/Ethnic Disparities Health inthe and Healthcare of USAdolescents: 2010 Vaccination and its Recommendation US,” inthe AcademyHealth Annual Research Meeting, MA,June Boston, H,FloresLau M,Lin G.“Adolescent Females and Human the Papillomavirus Vaccine –Factors Associated with PediatricDisparities?” AcademicVancouver, Societies, May BC, 2010(Poster Presentations) Spoken at Home and Health and Healthcare Disparities inUSAdolescents: Has Tincture the of Time Reduced Has Anything Changed Years?” the Over and Lau M,AvilaLanguage H,Flores Lin Primary R, G.“The Lau M,Avila H,Flores Lin R, G.“Racial/Ethnic Disparities Health inthe and Healthcare of USAdolescents: Vaccination and its Recommendation US” inthe Pediatric Academic Vancouver, Societies, May BC, 2010 H,FloresLau M,Lin G.“Adolescent Females and Human the Papillomavirus Vaccine –Factors Associated with Training Program Seminar, University of Texas of School Public April Health, TX, Dallas, 2010 “Immunization Concerns: Separating Fact from Fiction,” University of Texas Maternal and ChildHealth Presentation) Prevention,” American Academy of Pediatrics National Conference, San Francisco, 2010(Poster CA,October Pediatric Hematology Division Oncology Grand Rounds, and Educational and Experiences Improve Patient in Medical Education,” Department of Orthopedics Study of Parents of Hospitalized Children,” and “Do udy of Parents of Hospitalized Children,” Pediatric Public Health Association Annual Meeting, Denver, ation” Effective UT Series, LectureTeacher Austin, ation and Practice,” Grand Rounds, Texas Tech General Pediatrics 91 Member, Agency for Healthcare Research and Quality National Advisory Committee Subcommittee on on Subcommittee Committee Advisory National Quality and Research Healthcare for Agency Member, CHIP Programs and Medicaid for Measures Quality Healthcare Children’s Care Health and Health Pediatric on Council Committee Research Medicine/National of Institute Member, Measures Quality (AF4Q) Quality for Forces Aligning Foundation Johnson Robert Wood Committee, Advisory National Member, Program Initiative Research Nutrition and Child Health Network, Knowledge Nutrition and Expert, Child Health Member, National Advisory Committee, First Focus First Committee, Advisory National Member, Network Clinicians Migrant Council, Advisory Initiative Immunization Committee, Advisory National Member, on Research Multicultural for Network Foundation Johnson Robert Wood mentor, and Senior Investigator Health and Health Care Healthcare Children’s Improving for Programs Innovative Identifying on Committee Advisory National Member, (NICHQ) Quality Healthcare Children’s for Initiative National in California, Association Pediatric Academic Committee, Research Elected Chair, Member, Program Advisory Committee, University of Puerto Rico-Cambridge Health Alliance-Harvard Alliance-Harvard Health Puerto Rico-Cambridge of University Committee, Advisory Program Member, Center EXPORT University Pediatrics of Academy American Research, Pediatric on Committee Member, under- (for Program Century Scholars New Association Pediatric Academic Group, Advisory Member, pediatric residents) minority represented Committee Research (APA) Association Pediatric Academic Committee, Executive Member, Member, Board of Directors, Avance Dallas Avance Directors, Board of Member, Societies Meetings Academic Pediatric Reviewer, Abstract Program, National Foundation’s Johnson Robert Wood Committee, Steering and Network Scholars Member, Latinos for Communication Patient-Provider Improving Juntos: Hablamos Faculty Medical Amos (Minority) Harold Johnson Robert Wood Committee, Advisory National Member, Program Development Member, President’s Health Policy/Health Services Research Task Force Force Services Task Policy/Health Research Health President’s Member, Community Model of Evaluation and the Development for Program Committee, Advisory Project Member, in Dallas (DMCHID) Initiatives Health Committee Program Award Grant Pilot CTSI Texas Central North Section Member, Study Review Mortality Infant and Child Death Dallas County Member, Services Commission Human and Health Texas Committee, Advisory Frew Member, Appointed Hispanic the National by sponsored Summit, Leadership Hispanics and Disparities Health Member, Appointed Health ServicesMinority of Office Human and Health of Department the U.S. and Association Medical Services Commission) Human and Health the Texas by (nominated Founder and Director, Academic General Pediatrics Fellowship, UT Southwestern Fellowship, General Pediatrics Academic Director, and Founder Committee Advisory Clinical Research Children’s Section Member, Study Center Medical Children’s Committee, Service Steering Ambulatory Project Member, Center Medical Children’s Team, Project Management Demand Member, Clinical and UT Southwestern Committee, (CHRI) Steering Initiative Research Health Community Member, (CTSA) Sciences Award Translational Diversity Faculty for Force Task President’s Member, “Transition of Children with Complex Special Health Care Needs from the Pediatric to Adult Health Care Care Health Adult to Pediatric the from Needs Care Health Special Complex with Children of “Transition Center Medical Children’s Conference, Practice Advanced 4th Annual World” UT Southwestern General Pediatrics, of Division Director, “Adding Value: An Evidence + Value-Based Approach to Obesity,” Obesity,” to Approach + Value-Based An Evidence Value: “Adding MN, April Minneapolis, Medicine, Society General Internal for 2010 “How Parents Can End Bullying: Risk and Protective Factors Factors Protective Risk and End Bullying: Can Parents “How Pediatrics of Academy American in the US,” Child Bullying for CA, October Francisco, San Exhibition, and Conference National 2010 “Can Parents End Childhood Bullying? Risk and Protective Protective and Risk End Childhood Bullying? Parents “Can Randomized “A and in the US,” Child Bullying for Factors Substance and Violence Youth Reduce to Intervention Controlled BC,May Vancouver, Societies Meeting, Academic Pediatric Use,” 2010 Glenn Flores, M.D., F.A.A.P. M.D., Glenn Flores, Major Administrative or Leadership Responsibilities Major Administrative Jennifer Walsh, M.D. Walsh, Jennifer Christy Turer, M.D., M.H.S. M.D., Christy Turer, Rashmi Shetgiri, M.D., M.S.H.S. RashmiShetgiri, M.D., General Pediatrics 92 M.D., Shetgiri, Rashmi M.S.H.S. Vineeta Mittal, M.D. M.D.Angela Mihalic, M.D. Lee, Michael May M.D. Lau, Karen Latour, M.D. Kelly, R. Nancy M.D., M.P.H. Shelby Joseph, M.D. Gore,Lauren M.D. Vanthaya M.D. N.Gan, Matthew Cox, M.D. Abstract Reviewer, Pediatric Academic National Societies Meeting ofCo-Chair Culture, Ethnicity and Healthcare Special Interest Group, Academic Pediatric Association Center Leader, Bronchiolitis Task Force, tasked with developing care evidence-based guidelines,Children’s Medical Morbidity and Mortality Conference, University of Texas Southwestern and Children’s Medical Center Dallas Co-facilitator and co-organizer, Division of General Physician Team Inpatient Lead, Teaching Children’s Service, Medical Center Liaison, Inpatient General Pediatric University Consult Service, of Texas Southwestern Medical School Co-founder/Co-Chair, Family-Centered Care Special Interest Group, Academic Pediatric Association Associate ClinicalDirector of Inpatient for Division the Services of Pediatrics General Course Director, International Learning Preclinical Non-Credit Service Elective Director,Co-Course Public Policy and Healthcare Financing Director,Course Resident asEffective Teacher Workshop Paris Descartes Program Director, International Medical Exchange Program, Student Exchange Program with theUniversity of Pediatric of Greater Society treasurer Dallas- Nominating Committee, COMSEP on (Council Medical Student Education inPediatrics) Faculty Advisor, Academic Pediatrics Association- Educational Scholars Program Associate for Dean Student Affairs, University of SouthwesternTexas School Medical Member, Committee, Infectious Disease Texas Pediatric Society Billing and Compliance Officer, GeneralPediatrics Division,Southwestern UT Director,Course First Care ClinicalRotation, Children’s Medical Center Chairman, Pediatric Peer Committee, Review Children’s Medical Center Director, First Care Clinic,Children’s Medical Center Co-Chair, Texas Pediatric Committee Society on Adolescence and Sports Medicine Member, American Academy of Pediatrics Special Interest Group on Adoption &Foster Care Medicine Manuscript Reviewer, Pediatrics, Academic Pediatrics, and ClinicalPediatrics Abstract Reviewer, Pediatric Academic Societies Academic Pediatric Association Region VIICo-Chair Advocacy Program Co-Director, Pediatric UTSW Program Residency Medical Director, Charity Continuity Ball Crystal of Care Clinic Director, Continuity ClinicProgram for CMC/UTSW Pediatric Residents Medical Director, Medical-Legal Partnership for Children, Dallas Associate Program Director, Pediatric Program, Residency UTSouthwestern Member: Editorial Board Greater Pediatric Dallas Society Member: TheGlobalChild Health Educational Modules ProjectCommittee (GCHEMP) Manuscript Reviewer, Academic Pediatrics, Member, IDCommittee, Texas Pediatrics Member, TherapeuticsCommittee, Pharmacy Children’s Member, Advisory Committee, Texas Pediatric Precept Program Mentor, Medical Student College Faculty Preceptor, Pediatric Resident Continuity Clinic,Children’s Faculty Advisor/Sponsor, Pediatric Interest Group Program Co-Director, Subspecialty Ambulatory Rotation: Senior ClinicalResident Director,Course Pediatric Preceptorship: ClinicalStudent Director,Course Pediatric Preceptorship: Pre-clinical Student Associate Director, Pediatric Clerkship Director, Medical Student Clinic Member, Texas Department of Health Advisory and Panel, Human MEDCARES Austin, Services TX Medical Director, Assault Sexual Forensic Examination Team, CMC Dallas Medical Director, REACH Program, Children’s Medical Center Dallas. Pediatrics and Hospitalists Medicine Group Faculty General Pediatrics 93 ersity of Texas Health Science Education Award Science Education Health Texas of ersity l, elected by graduating class of 2010. of class graduating elected by l, D Magazine D Magazine D Magazine Teacher Award, MS1 Class, 2009-2010 Award, Teacher MS2 Class, 2009-2010 Award, Teacher D Magazine Texas Monthly Texas Elected to the American Society the American Elected Clinical Nutrition to of Funds Planning (CATCH) Child Health to Access Community (AAP) Pediatrics of Academy American Needs.” Healthcare Special with Youth of “Transition title: grantStudy Awarded UT Southwestern Clinical Research Scholars Award Scholars Clinical Research UT Southwestern Awarded UT Southwestern Pediatrics, of Professor Assistant to Promoted in Dallas (PDEMCHID) Initiatives Community Model of Evaluation and the Development for Program Grant, Best in Dallas, Doctors Doctors, Super Texas UT Southwestern Preclinical Teaching Award, Clinical Medicine, Class of 2012 Class of Medicine, Clinical Award, Teaching Preclinical UT Southwestern Univ Science Education, in Health Finalist, Innovation Program Grants Small Sciences Education, Health Texas of University Grant, Educational UT Southwestern Residency, Pediatric Award, Teaching Faculty 2010, UT Southwestern Class of Award, Teaching Clerkship Core The Best Pediatrics Specialists in Dallas 2010, Pediatrics The Best Marsha Faculty Commencement UT Southwestern Outstanding UT Southwestern Outstanding UT Southwestern conference invitational A Second Century Achievement of Education: in Medical Horizons New AAMC/AMA attendee The Best Pediatrics Specialists in Dallas 2010, Pediatrics The Best Chapter Gamma Society, Medical Honor Omega Alpha in the Alpha membership for Nominated of “Initiation title: Study Medicine. of College Baylor at grant a research for received funding and Co-Investigator Department” Emergency in the Pediatric Regimens Care Asthma Chronic Specialists in Dallas 2010, Pediatrics The Best UT Southwestern Pediatrics, of Professor Associate to Promoted 2010 Helen Rodríguez-Trías Social Justice Award from the American Public Health Association Health Public the American from Award Social Justice Rodríguez-Trías 2010 Helen December 2010 the Year, of Child Advocate CollinCounty, of Center Advocacy Children’s UT Southwestern Pediatrics, of Professor Associate to Promoted Monthly Texas Doctors, Super Texas America of Research Consumer Pediatricians, Top America’s to Guide National Institutes of Health (NIH) R01 grant, “A Randomized Trial of Effects of Parent Mentors on Insuring Insuring on Mentors Parent of Effects of Trial Randomized “A R01 grant, (NIH) Health of Institutes National Development Human and Child Health of Institute National Shriver Kennedy Eunice Children,” Minority (NICHD) Innovations Care Health in AHRQ asthma featured with children minority for intervention Parent-mentor Exchange Force Services Task Preventive States United to Appointed Director, Pediatric Diagnostic and Consultation Service, Children’s Medical Center Medical Service, Children’s Consultation Diagnostic and Pediatric Director, Committee Clinical Faculty Chair, Master, Gladys Fashena College, UT Southwestern Medical School Medical UT Southwestern College, Fashena Gladys Master, Jennifer Walsh, M.D. M.D. Walsh, Jennifer M.H.S. M.D., Christy Turer, M.D. Steinberg, Joel M.S.H.S. Rashmi Shetgiri, M.D., Vineeta Mittal, M.D. Mittal, Vineeta Mihalic,Angelia M.D. Michael Lee, M.D. N. Gan, M.D. Vanthaya M.D. Cox, Matthew Glenn Flores, M.D., F.A.A.P. M.D., Glenn Flores, Honors and Awards Joel Steinberg, M.D. M.D. Steinberg, Joel General Pediatrics 94 Genetics / Metabolism 95 Genetics/Metabolism Perrin White, M.D. White, Perrin Interim Director, Pediatric Director, Interim in North Texas North in Genetics / Metabolism / Genetics , from Harvard, from College, Cambridge, Massachusetts, in Inborn Metabolism of Errors The largest clinic specializing in the diagnosis and treatment of children children of clinic withspecializing largest The in treatment and diagnosis the magna cum laude 1972, and from Harvard his1972, M.D. Medical Massachusetts, Boston, School, in in pediatrics residencies Hopkins Baltimore, Johns Hospital, held at He 1976. and 1981, to 1980 from Hospital York New and at 1978 to Maryland, 1976 from he held a research fellowship in developmental molecular biology at Rockefeller awards number a of has received He 1980. to from 1978 York, New University, including the of the Endocrineand Ernst Society honors, Oppenheimer Award Health of the of Society Pediatric has Institutes Research. He for Award and the Mead-Johnson National the for committees advisory numerous on served severaland on editorial boards. Faculty NewmanAudre was the hold firstthe to Perrin C. Professor, White, M.D., Rapoport Distinguished was Chair recruited He to in Pediatric Endocrinology. UT Southwestern as Director the of Pediatric Endocrinology program in 1994 was he Professor where from Cornell Medical University College in York, New assumed he Interim of Pediatrics. the the Directorof of role Pediatric In 2010, Genetics White & Metabolism several program. research on has conducted Dr. the including and metabolism biosynthesis hormone diseases steroid of genetic congenital of forms adrenal common most hyperplasia. White his received Dr. A.B.,
Dr. Ralph DeBerardinis research effortsDr. expand to in continues theareas cellular division’s that include regulation metabolismof in normal cells and in cancer and in the diagnosis pediatric and of treatment metabolic diseases. UT laboratory at coordinates the Southwestern, science a basic operates newborn screeningHe referral service at Pediatric andGenetics the attends and on in-patient Metabolism service.Children’s, The The division is a programsvital for parttraining of UT Southwestern’s medical fellows students, residents, and allied health teaching in Faculty a major the professionals. role first play year of medical the program school and train third-year medical students as part their of pediatric They rotation. play also an important part Pediatricsin the and Medical Genetics programs. residency The Division of Pediatric Genetics and Metabolism is a major resource for clinicalfor PediatricTexas, resource of MetabolismGenetics Division genetics North The with is a major in and thatare unique inclinics the The wasdivision region. Children’s at referrals Texasthe to accept first clinicNorth in Department Health’s newborn of screeningfrom the Texas program biochemical disorders, and is the for largest clinic specializing in the diagnosis children and of treatment with metabolism inborn of in errors North Texas. Referrals from all are hospitals received in the the of Dallas/Fort other children’s as well as Metroplex from Worth distantmore areas. Faculty and staff operate multispecialtyonly the clinic patients for with Down syndrome in the special and have region interests in the diagnosis a variety as such of and conditions management other genetic of Marfan syndrome, imperfecta The osteogeneisis division skeletaland provides of also otherdisorders development. clinical services for the major clinical laboratories at UT Southwestern that deal with genetic conditionsmolecular diagnosis, including cytogenetics and disease metabolic laboratories. the Genetics / Metabolism 96 Kartik Rajagopalan, Graduate Student Graduate Rajagopalan, Kartik Student Graduate Mullen, Andrew Christopher Research Assistant II Chambers, Ph.D., Cheng, Tzuling Post-doctoral Researcher Chendong Yang, M.D., Ph.D., Scientist Research II Assistant Research Jessica Sudderth, Nurse Advanced Practice RN, M.S.N., Spahis, Joanna CCC-SLP, M.S., Quinn, Speech Therapy Christine Counselor Genetic CGC, Michel, M.S., Donnice Gotway, M.D.,Garrett Resident Ph.D., Genetics Medical ResidentPavel Genetics M.D., Pichurin, Medical LD, RD, Nutritionist Green, M.S., Katie LMSW-ACP,Debbie Clark, Worker, Social Syndrome Clinic Down Senior Counselor Genetic CGC, M.S., Brookshire, Gail LMSW, Worker, Barton, Social Martha Metabolic Clinic andResearchClinical Staff Development in Clinical Genetics, 1974-1977 Genetics, Development Clinical in Center Development, for Child School Fellow, ofMailman Medicine, of Miami Child Resident,FL, Neurology, Hospital, 1972;1972-1973; Affiliated University of Miami University Post-doctoral training: M.D.,School of FL, 1970 Medicine, Education: Clinical expertise: expertise: Clinical Associate ProfessorClinical EstherCarlin,Mary M.D. 1980; Fellow, 1980-1982 Genetics, Post-doctoral training: University OH, School Cleveland, ofM.D. Ph.D., Medicine, and 1977 Education: genetic disorders in of metabolism fatty-acid studies Research expertise: screening newborn expertise: Clinical TeachingDistinguished Professor, Southwestern UT Professor,Associate Eugene Development the Center and McDermott and for Pediatrics Growth Lewis J. Waber, Ph.D. M.D., Fellow, 2006-2007 Genetics, 2000-2005; Biochemical combined program, Genetics Medical Post-doctoral training: Ph.D.,Philadelphia, 1998; M.D., 2000 Education: growth cell tumor and metabolism errors of metabolism, Research expertise: Development and Eugene Center McDermott for Growth Human Research Medical in Scholar Sowell Family ProfessorAssistant Genetics of and Pediatrics Ralph DeBerardinis, Ph.D. M.D., Barry (College) Barry 1966; University, University B.S., of Shores, Miami FL, Miami Franklin and Marshall College, Lancaster, PA, College, 1970; A.B., Western Marshall and Case Reserve Franklin Joseph’s St. 1992; University, University of B.S., Pennsylvania, Philadelphia, Pediatric genetics, biochemical genetics, inherited metabolism disease and and disease metabolism inherited genetics, biochemical genetics, Pediatric Pediatric genetics, development, dysmorphology, Down syndrome Down dysmorphology, development, genetics, Pediatric Management of pediatric patients with inborn errors of metabolism and Growth factor-stimulated signal transduction pathways, pediatric inborn inborn pathways, pediatric transduction signal factor-stimulated Growth UT Southwestern/Children’s, Intern and Resident, Pediatrics 1970- Southwestern/Children’s, Resident, Pediatrics and UT Intern Johns Hopkins Hospital, Baltimore, MD, 1977- Resident, Hospital, Baltimore, Johns Pediatrics, Hopkins The Children’sThe and of Hospital Philadelphia, Resident,PA, Pediatrics Genetics / Metabolism 97 The DeBerardinis laboratory is interested in understanding the the understanding in interested is laboratory DeBerardinis The metabolic activities that support cell growthin and proliferation normal daughter cells, cells produce and to which in In order cancer. occur with the their of cell each round cells cycle, double to need This is a tremendous acids). and lipids nucleic (proteins, biomass into challenge requiring building energy, blocks and the coordination them allocate DeBerardinis Dr. is metabolic pathways. a large of number of and nutrients exploring the that idea these activities metabolic are orchestrated which pathways, abundant transduction signal up factor-stimulated growth take by to cells direct wants signal understand to He metabolic pathways. how the proper transduction impacts of states metabolic fluxesduring physiologic cell proliferation (e.g., embryogenesis, wound healing, activation of the immune system) and during pathological states (e.g., cancer). To do this,do the DeBerardinisthe To andimmune during lab uses system) cancer). a combination pathological states (e.g., with metabolic flux cell coupled techniques and in biology of biochemistry, molecularanalysis biology, using mass spectrometry and magnetic nuclear and resonance, animal metabolism projects Current of and models cancer. imaging developing identifyinclude to probes abnormal metabolic activities in tumor and in children with metabolic diseases. Division faculty inmedical the are involved training first-year students, specifically UT of Southwestern’s inthe is the director the of embryology course and and Waber genetics co-director embryology courses.biochemistry, Dr. theof genetics course. As part their of pediatric third-year medical rotation, through students rotate the outpatient clinics and with are provided The a casedivision managesMedical conference. a Geneticsresidency trainingprogram and is an important part the of Pediatrics program. residency Presentations/Teaching Activities Presentations/Teaching The Metabolic Disease The ServiceTexasNewborn Screening Program.also for referral the functions center a major as programThis state-wide seeksidentify to newborn babies 29 with of treatable different diseases, any of whichare many in nature. A largegenetic/metabolic fraction the each year of 405,000 are evaluated Children’s. born in at babies Texas a metabolic abnormality have the to on newborn the screen, is found familyWhen in a baby North to Texas is referred our team definitive for diagnosis, caretreatment, long-term necessary.and if Texas Newborn Through Screeningthe Program, than children more 75 with metabolic diseases and are coordinated year, of identified the care each these children the by Disease Metabolic significantly Service Children’s at their survival improves development. and The Metabolic Disease The Service provides evaluation testing childrenand for with suspectedor of known errors inborn metabolism specificmetabolism. of as about Blood, well errors asinborn urine, education enzyme DNA analyses and diagnosisare performed for and treatment, and nutritional evaluation and counseling and psychosocial assessment are provided. clinic have more than fifty collective years of experience in caring for children with Down syndrome and provide provide and syndrome Down with children for caring in Clinical Activities experience of years collective fifty clinicalfocused activities are Division’s The in Children’s at three than Facultyareas. staffand Downin the syndrome more have clinic children treatment for and their familiescomprehensive including medical counseling, genetic management, physical, evaluation and psychosocial recommendations, support, screening development and referralspeech and motor for behavioral and and psychiatric referral or problems community to educational therapies. intervention for agencies or disorders metabolic retardation, mental or delay developmental defects, birth involving conditions with Children known evaluation suspected and receive or disorders testing genetic in the Genetics Clinic. Chromosomal metabolic analysis disease diagnosis genetic and as DNA for of well as is provided, psychosocial nutritional assessment, evaluation case with management and referral counseling medical to and comprehensive specialists, community and resources Family groups. support history analysis counseling and genetic discuss also to options are reproductive available. Research Activities Research Genetics / Metabolism 98 Kartik Rajagopalan Kartik Mullen Andrew Tzuling Ph.D. Cheng, Lewis J. Waber, M.D., Ph.D. DeBerardinis,Ralph M.D., Ph.D. Awards and Honors Lewis J. Waber, M.D., Ph.D. J. DeBerardinis,Ralph M.D., Ph.D. Major Administrative Responsibilities orLeadership t t t Lewis J. Waber, M.D., Ph.D. t t t t t t t t t t t DeBerardinis,Ralph M.D., Ph.D. Cancer Biology Training Biology Cancer Grant UT Southwestern T32Grant Genetics Training Biology CPRIT Cancer Grant Member, Texas Academy of Health Education Science Excellence inEducation Teaching Award, Pre-Clinical, Classof 2012for MS1 Co-investigator on CPRITGrant, “Novel MRIand for MRSmethods imaging cancer cellmetabolism.” Probes: Novel Reagents for Monitoring Metabolism” Cell Cancer Principal Investigator of Welch Foundation Award, “Dynamic Nuclear Polarization of Small Molecule Metabolic funding programthis theMetabolism?” highest-scoring Thiswas proposal among approximately 900 applicationsthe firstyear in of Prinicipal Investigator of CPRITGrant, “Can Glioblastoma Consultant, Newborn Screening Program, Texas Department of Health Director, Program Residency Genetics UT Southwestern High Impact/High RiskGrants Program MacArthur Foundation Fellowship Program American Association for Research Cancer Program Committee (Cellular and Molecular Metabolism Section, Biology and Cancer Subcommittee), Lecturer, (first-year Medical medicalstudents) Biochemistry DirectorCo-course and Lecturer, Medical (first-year Genetics medicalstudents) DirectorCourse and Lecturer, Medical (first-year Embryology medicalstudents) Lecturer, inMedical Cases (third-year Genetics medicalstudents) Lecturer, (first-year Biology Cancer graduate students) Lecturer, Medical (first-year Genetics medicalstudents) Conference, Austin, November TX, 2010 “Multidisciplinary Studies inTumor Metabolism: Meta Future Conference, Edinburgh, Scotland, September 2010 “Mitochondrial Metabolism inTumor Forgotten, Cells: But Not Gone,” and Cancer Metabolism: Pathways to the River, NY, July 2010 “The Warburg Effect, The Truncated TCA Cycle, Other and Metabolic Targets in Tumor Cells,” Pfizer, Pearl Training XVIII: Intermediary Metabolism and Cancer, 2010 TX Dallas, “Cancer Therapy Based on Integrated Understanding Cancer Genetics andof Metabolism,” Symposium and Teleconference, April 2010 Diverse “The Functions Glutamineof in Cancer,”Celland Biology Metabolism, Johnson and Johnson, Canada, March 2010 Proliferation and Tumorigenesis,” Metabolism and “Alternative Metabolic Strategies for Growth inGlio of British Columbia, Vancouver, March Canada, 2010 “Understanding Mitochondrial Metabolism inTumor Growth,” Symposium on Metabolism, Cancer University Research on Malignant Gliomas, Naples, Italy, February 2010 “Molecular for Basis Reprogramming the of Cancer Cell Cancer Progression,Cancer Keystone Symposium, Vancouver, blastoma: Glucose vs.Glutamine for Support of cell bolic Targetsbolic inGlioblastoma,” CPRITInnovations Metabolism,” International Workshop for Translational Growth Suppressed be by Targeting Glutamine Hematology-Oncology 99 Hematology-Oncology Hematology-oncology patient activities patient LegacyHematology-oncology at the at campus Children’s beganin 2008 May in Legacy’s Ambulatory Pavilion, and in early 2009 an service inpatient was initiated selected children for with cancer and hematologic the support growth continued this of program, To full-timeconditions. four faculty in physicians the now CCBD devote much of their time to clinical activities on the Legacy staffsupport aswill well assure success of of continued the the itsone of the Legacy asfirst project, to States kindUnited Dallasin the campuses. These additional faculty and An additional development during 2010 was the growth duringAn 2010 the additional of clinical development and translational research program connections with Amy excellent Pass, has who developed the spearheaded Dr. in national by neuroblastoma the for of Center one Kids’ Out Cancer, Wipe is being by supported work Her research community. neuroblastoma outstandingCancer and Disorders’ local Blood fundraising organizations. A major area of growth during 2010 was the Hematopoietic Stem Cell (Bone Marrow) Transplantation Program Transplantation Cell Marrow) Stem area growth of was (Bone theA major Hematopoietic during 2010 the joined UT Andrew who under Southwestern Koh, the faculty Dr. leadership in July 2009 following his recruitment from the Dana Farber Cancer Institute and Harvard Medical in His School Boston. arrival successful has fostered transplantfundraising, D6 Hematology-Oncology the 12-bed unit of new within completion the 24-bed Tower facultyUnit, children of coverage receiving recruitment inpatient and for model transplantation a new a cadre by of has successfully Koh Dr. providers. engineeredexperienced managed mid-level new care contracts and collaborative arrangements with other pediatric in the centers oncology as South a major establish and to Southwest Children’s transplantation. in patients of need referral for Plans are recruit center to additional clinical and transplant laboratory specialists and early 2012. during 2011 Continued progressContinued was made in the expansion clinical of the program’s facilities In 2007, December the CCBD. for activitiesoutpatient temporarily the to third moved of Bright Building, floor the across streetthe mainfrom the during sizemore than space the of previousdoubled clinic. the development renovated facility.hospital The A major the on facility sixth2009 Hematology-Oncology 24-bed a new to inpatient was of Children’s the at move floor the With substantial D. advice from a Family Council Tower new parents, patients’ the of unit was designed optimize to and patients families.comfort for beds specifically 12 includes It stem cellfor designed transplantation. CCBD The C. Construction unit analso will of outpatient entirely new additional was provided beds Tower in the adjacent 18 next the during followed with the aimbegin the At completing facility, first of in phase of by that year. early time end 2011, the the hematology new the the to location Building Bright its from willmove CCBD the of component bringing the of project, clinic, the outpatient satellite oncology completion pharmacy, by laboratory 24 months to The operation. finalhospital into and“master infusion plan” stepin construction room/day the CCBD willinvolve administrativeof B6 and space on ten additionalFamily C6. beds on inpatient CCBD The Counsilto be continue instrumental in providing practical guidance this regarding how space will new best serve and our patients families. however, remain actively engaged in teaching, mentoring, consultative care and clinical research. The Department Department The research. clinical and care consultative Buchanan, ThisGeorge Division leadershipyear change. Dr. Early a major plansbrought in year, for withit also the mentoring, teaching, in Buchanan engaged will, Dr. announced since 1980. hishas he held plans from the step down Director, to position leadership actively remain however, a search assembled committee local of Lister, George academic and Dr. administrativeChair, a and leaders conducted ended, a finalisthopefully waswho identified As 2010 Director. a new national searchrigorous for will takehelm the the the by of summer CCBD 2011. of In 2010 Children’s Medical Center’s Oncology Program was ranked No.16 in the United States by U.S. News and News U.S. by States in the Program Oncology United was Medical ranked Center’s Children’s No.16 In 2010 Report, again the highestWorld ranking any medical of than subspecialty More million $20 program Children’s. at in community philanthropic support has been garnered during the past three years in recognition the of program’s than In addition, more millionreputation. $3 in research grants from NIH funding and other peer-reviewed agencies faculty of A number investigators. awards and Hematology-Oncology was to other received forms awarded members national theirof recognition Areas growth for continued outstanding of during in work 2010. the near future include sickle The celldivision’s disease, in cell research cancer. andstem transplantation, neuroblastoma, basic thrombosis blood 10 and programscancer ultimate to the five among in world. goal top become is to the During 2010 there were 30 faculty there were During in members dedicated the fulfilling to Hematology-Oncology Division of 2010 the in care, leadership of missions patient research and education, advocacy involvingprogram’s and disorders blood childhood malignancies. The is nationallydivision distinguished its of design investigator-initiated for conduct and and clinical NIH-funded multi-center trials involving childhood sickle cell cancer, disease disorders. and hemorrhagic program largestAs the kind its in the States, of major of the the 10 and division one United in North provides Texas to hundreds patients with of Children’s at care in uncommon Cancer the for Center and Blood (CCBD) Disorders disorders, and alsoprimary andoutreach educationalfor complex offers resources that consultative includes and and referring inby expanding physicians program the numbers The region. considerably to its continues patient grow and competitive manageddespite care pressures. 100 Hematology-Oncology the Arnold Gold Award Arnold Gold the for Humanism inMedicine from American the Association of Medical Colleges. recipientthe of Mentor the Award inClinicalResearch of from Hematology American the Society and in2010received received Distinguished the Career Award from Americ the Pediatric Hematology-Oncology and on Executive the Committee of of Hematology. American the Society In 2007he repeatedly recognized asone of Doctors inAmeric “Best the Faculty of Texas (CPRIT). Prevention Institute Cancer Research and the 2010, from members in to Dr.faculty Amatruda grants James including awards received noteworthy by grant research are Equally Colleges. of Association Medical American from the included Dr. George Buchanan’s receipt November in 2010 Gold Arnold Award of the Medicine in for Humanism 2010. toselected become for during newResearch members honorsyear Pediatric Society of the Other the during members faculty of Pediatric were four Department the among Neunert, Cindy and Koh, Crary Shelley Andrew continuesatThe many CCBD levelsto be faculty recognized for excellence.its For three of example, faculty, its Drs. Oncology faculty. conducted research Hematology- by the of translational basic and continued growth the to assure modernized and beenappreciably Southwestern laboratory spaceat has UT expanded facilities, clinical of the growth to addition the In 2010. visits patientsby during 3,500 ship.” had than more Legacy at The outpatient CCBD facility to aworld-class “mother academic linked tightly facility provide asuburban complex in care hematologic cancer and Director, Pediatric Hematology-Oncology George R.Buchanan,M.D. Oncology, 1998-2001 Denver, Resident, Pediatrics, 1994-1997; UTSouthwestern, Fellow, Pediatric Hematology- Post-doctoral training: Education: expertise Clinical/research Assistant Professor Kristine W. Appel, M.D. M.D., 1999-2004 Oncology, 1997-1999;Children’s Hospital MA,Fellow, Boston, Laboratory of Leonard Zon, Medicine, 1994-1996;Dana-Farber/Partners Care, Cancer MA,Fellow, Boston, Hematology- Post-doctoral training: MO, M.D., 1993; Washington University, Ph.D., and Biology Physiology, Cell 1993 Education: ofgenetic models cancer expertise: Clinical/research Assistant Professor, Pediatrics, Molecular and Biology Internal Medicine James F. Amatruda, M.D., Ph.D. Harvard University, Cambridge, MA, A.B., 1986;Washington University, St. Louis, UT Austin, B.A., 1990;UTSouthwestern, M.D., 1994 students, residents, and fellows at UTSouthwestern. Dr. Buchanan hasbeen He received Teaching Excellence Awards on numerous occasions from and at oncology inpediatric Dana-Farber Institute Cancer inBoston. 1970 to 1973 and afellow wasthen inhematology at Children’s Hospital at inpediatrics residency Children’s Memorial Hospital inChicago from medical degree at University the honors from Drake University, Moines, Des Iowa, in 1966and earned his hematology-oncology.in academicpediatric Dr. Buchanan graduated with students, residents, fellows and junior faculty engaged inor planning careers and iron as deficiencies. researchserves advisor He and mentor medical to immune spherocytosis hereditary thrombocytopenia, celldisease, sickle hemorrhagic disorders and general hematology. Research interests include and isnationally known hemoglobinopathies, insickle for hisexpertise FundCancer Distinguished Chair inPediatric and Hematology Oncology Comprehensive Center. Sickle Cell Dr. Buchanan holds Children’s the Pediatric at Oncology UTSouthwestern and Director of Southwestern the Medical Director for CCBD, the Director of Barrett the Family Center for George Buchanan, R. M.D., Professor and Division Director, isthe University of of Colorado School Medicine/The Children’s Hospital, Brigham and Women’s Hospital, MA,Resident, Boston, Internal : General pediatric hematology pediatric and: General oncology Germ celltumors, Germ molecular basisof Ewing’s sarcoma, zebrafish an Society of Pediatrican Society Hematology-Oncology, in2008was a.” asPresident He served of of American the Society of Chicago in1970.He his performed Hematology-Oncology 101 Palliative care, end-of-life care, including hospice and bereavement and hospice including care, end-of-life care, Palliative General pediatric hematology and oncology, sickle cell disease oncology, General pediatric and hematology Genetic control of cell lineages, programmed cell death programmed cell lineages, of Genetic control Brain tumors, long-term follow-up of childhood survivors of cancer follow-up long-term tumors, Brain General pediatric hematology-oncology General oncology, stem cell transplantation, Phase I therapies, and and Phase I therapies, cell transplantation, stem General oncology, Indiana University, Bloomington, Resident, Pediatrics, 1999-2003; Pediatrics, Resident, Bloomington, University, Indiana Children’s Hospital Boston, MA, Resident, Pediatrics, 1992-1994; Pediatrics, Boston, MA, Resident, Hospital Children’s James Whitcomb Riley Hospital for Children, Indianapolis, IN, Indianapolis, Children, for Riley Hospital Whitcomb James 1993-1996; Johns Pediatrics, Resident, UT Southwestern/Children’s, SUNY Health Science Center at Syracuse, Resident, Pediatrics, 1989- Pediatrics, Resident, Syracuse, Science at Center Health SUNY Texas Tech Health Science Center, Amarillo, Resident, Pediatrics, 2003- Pediatrics, Resident, Amarillo, Science Center, Health Tech Texas Valparaiso University, IN, B.S., 1995; Indiana University, Bloomington, M.D., 1999 M.D., Bloomington, University, 1995; Indiana IN, B.S., University, Valparaiso Texas A&M University, College Station, B.S., 1989; UT Southwestern, M.D., 1993 M.D., 1989; UT Southwestern, B.S., Station, College A&M University, Texas Universidad del Norte, Barranquilla, Colombia, M.D., 1999 M.D., Colombia, Barranquilla, Norte, del Universidad Johns Hopkins University, Baltimore, MD, B.A., 1983; SUNY at Stony Brook, Ph.D., Ph.D., Brook, Stony at 1983; SUNY B.A., MD, Baltimore, University, Hopkins Johns Indiana University, Bloomington, B.S., 1982; M.D., 1986 1982; M.D., B.S., Bloomington, University, Indiana CUNY Medical School at City College, New York, B.S., 1987; SUNY Health Science Health 1987; SUNY B.S., York, New College, City School at CUNY Medical MaryEllen Cavalier, M.D. MaryEllen Cavalier, Professor Assistant Clinical/research expertise: Education: training: Post-doctoral 2003-2005 Hematology-Oncology, Pediatric Fellow, J. Scott Cameron, M.D., Ph.D. M.D., Cameron, Scott J. Biology Molecular and Pediatrics Professor, Assistant Clinical/research expertise: Education: 1992 Boston, MA, M.D., University, 1988; Harvard training: Post-doctoral 1995-1998; Pediatrics, Boston, MA, Fellow, Hospital Cancer Institute/Children’s Dana-Farber MA, Cambridge, Technology, of Institute Massachusetts Institute, Medical Hughes Howard 1996-2001 Biology, Fellow, Daniel C. Bowers, M.D. Daniel C. Bowers, Professor Associate Experience After the Cancer and Neuro-oncology Director, Clinical/research expertise: Resident, Pediatrics, 1986-1989; UT Southwestern, Fellow, Pediatric Hematology-Oncology, Hematology-Oncology, Pediatric Fellow, UT Southwestern, 1986-1989; Pediatrics, Resident, 1992-1993. Hematology-Oncology, Pediatric Fellow, 1989-1992; Research Education: training: Post-doctoral 1996- Oncology, Pediatric Fellow, MD, Baltimore, Medicine, School of University Hopkins 1998 Epidemiology, Fellow, University, Hopkins 1999; Johns Robert O. Bash, M.D. Robert O. Professor Associate Care Palliative Director, Clinical/research expertise: Education: training: Post-doctoral Assistant Professor Assistant Clinical/research expertise: Carmen Ballestas, M.D. Ballestas, Carmen Education: training: Post-doctoral 2006; University of Alabama at Birmingham, Fellow, Pediatric Hematology-Oncology, 2006- Hematology-Oncology, Pediatric Fellow, Birmingham, at Alabama of 2006; University 2009 Victor M. Aquino, M.D. M. Aquino, Victor Professor Associate Clinical/research expertise: febrile neutropenia in pediatric cancer patients pediatric in cancer neutropenia febrile Education: 1989 M.D., Syracuse, at Center training: Post-doctoral Bone 1992-1995; Fellow, Hematology-Oncology, Pediatric Fellow, Southwestern, 1992; UT Bone Fellow, WA, Seattle, at Cancer Center Hutchinson 1994-1995; Fred Transplant, Marrow 1996 Transplant, Marrow 102 Hematology-Oncology University of Minnesota, Minneapolis, Fellow, and Marrow Blood Transplant, 2005 Pediatrics, 1997-2001;UTSouthwestern, Fellow, Pediatric Hematology-Oncology, 2001-2005; Post-doctoral training: of Medicine, Jackson, M.D., 1997 Education: transplantation for non-oncologic diseases Clinical/research expertise: Clinical/research Director, Medical Student and Resident Education Assistant Professor Jennifer A.Cox, M.D. Pediatrics, 1996-1999; UTSouthwestern, Fellow, Pediatric Hematology-Oncology, 1999-2002 Post-doctoral training: Center, Tulsa, M.D., 1996;UTSouthwestern, M.S.C.S., 2008 Education: disorders during catheter-related childhood, thrombosis expertise: Clinical/research Director, Hemophilia and Thrombosis Program Associate Professor Janna M.Journeycake, M.D., M.S.C.S. Health and Human Development, Fellow, Pediatric Scientist Development Program, 2007-2010 Southwestern, Fellow, Pediatric Hematology-Oncology, 2006-2010;National Institute of Child Post-doctoral training: Southwestern, M.D. and Ph.D., 2004 Education: sarcoma, microRNA-based cancer therapeutics expertise: Research Instructor Mark E. Hatley, M.D., Ph.D. 2007 Fellow, Pediatric Hematology-Oncology, Pediatric and Blood Marrow Transplantation, 2004- Post-doctoral training: and Foundation, Rochester, MN,Ph.D., M.D., 2001 Education: agentsnew lymphoma and pediatric Iclinical trials, Phase expertise: Clinical/research Assistant Professor Paul Harker-Murray, M.D., Ph.D. NY, Fellow, Pediatric 2005-2009 Hematology-Oncology; 2005; Weill Medical Cornell College/Memorial Sloan-Kettering Cancer Center, New York City, Post-doctoral training: Providence, RI,M.D., 2002 Education: expertise: Clinical/research Assistant Professor Alexander Gozman, M.D. Pediatrics, 2000-2003;UTSouthwestern, Fellow, Pediatric Hematology-Oncology, 2003-2006 Post-doctoral training: M.D.,LA, 2000;UTSouthwestern, M.S.C.S.,2009 Education: splenectomy, and spherocytosis other non-malignant hereditary hematologic disorders expertise: Clinical/research Assistant Professor Shelley E. Crary, M.D., M.S.C.S. Mississippi State University, Starkville, B.S., 1993;University of Mississippi School Brown University, Providence, RI,B.S. and B.A., 1998;Brown Medical School, Rhodes College, Memphis,Rhodes TN,B.S., 1991;University of Oklahoma Health Sciences University of Oklahoma, Central Edmond, B.S., laude, summacum 1995; UT University of Michigan, Ann Arbor, B.S., 1993;Mayo Medical Mayo School, Clinic Washington University, St. Louis, MO, B.A., 1996;Tulane University, New Orleans, Development of mouse sarcoma of dissection microRNA’s models, role in University of Mississippi of Medicine, School Jackson, Resident, UTSouthwestern/Children’s, Resident, Pediatrics, 2004-2006; UT Children’s Hospital of Philadelphia, PA, Resident, Pediatrics, 2002- University of Oklahoma of College Medicine, Tulsa, Resident, University of Minnesota, Minneapolis, Resident, Pediatrics, 2001-2004; Vanderbilt University, Nashville, TN,Resident, Immunodeficiency, clinical stem celltransplantation and Hemophilia and thrombosis, thrombotic and hemorrhagic oncology, pediatric General hematopoietic celltransplantation, Hemophilia and thrombosis, complications vascular of General pediatric hematology-oncology pediatric General Hematology-Oncology 103 .S., magna cum laude, 1998; UT Southwestern, 1998; UT Southwestern, .S., magna cum laude, Pediatrics, 1989-1990; Princess Margaret Hospital Hospital Margaret 1989-1990; Princess Pediatrics, ns pathogenesis, Pseudomonas aeruginosa Pseudomonas pathogenesis, ns esident, Pediatrics, 1990-1992; University of Colorado Colorado of 1990-1992; University Pediatrics, esident, Neurofibromatosis, optic gliomas, tumorgenesis, general pediatric tumorgenesis, optic gliomas, Neurofibromatosis, Hemophilia and thrombosis, immune thrombocytopenia and and thrombocytopenia immune thrombosis, and Hemophilia of development neuroblastoma, for Clinical trial development Sickle cell disease, pediatric hematology-oncology, health services, cell disease, Sickle pediatric hematology-oncology, Bone and soft tissue tumors, fellowship training fellowship tumors, tissue soft Bone and Stem cell transplantation, infectious diseases infectious in the cell transplantation, Stem Eastern Virginia Medical School, Norfolk, Resident, Pediatrics, 2001- Pediatrics, Resident, School, Norfolk, Medical Eastern Virginia Resident, OH, Center, Medical Hospital Children’s Cincinnati UT Southwestern, Post-doctoral Research Fellow, 2001-2002; 2001-2002; Fellow, Research Post-doctoral UT Southwestern, UT Southwestern/Children’s, Resident, Pediatrics, 2002-2005; Chief Pediatrics, Resident, UT Southwestern/Children’s, St. Lawrence’s Hospital, Dublin, Intern, Adult Medicine and Surgery, Surgery, and Medicine Adult Intern, Dublin, Hospital, Lawrence’s St. Children’s Hospital, Boston, MA, Resident, Pediatrics, 1996-1999; 1996-1999; Pediatrics, Boston, MA, Resident, Hospital, Children’s College of William and Mary, Williamsburg, VA, B.S., 1997; Eastern Virginia 1997; Eastern Virginia B.S., VA, Williamsburg, Mary, and William of College cum Arts B.A., & Sciences, of College Philadelphia, Pennsylvania, of University The Royal College of Surgeons, Dublin, Ireland, M.D., 1986 M.D., Ireland, Dublin, Surgeons, of College The Royal Texas Tech University, Lubbock, B Lubbock, University, Tech Texas Harvard College, Cambridge, MA, A.B., 1988; Oxford University, Pembroke Pembroke University, 1988; Oxford MA, A.B., Cambridge, College, Harvard University of Notre Dame, IN, B.S., 1992; UT Southwestern, M.D., Ph.D., 2001 Ph.D., M.D., UT Southwestern, 1992; IN, B.S., Dame, Notre of University Amy Kun Pass, M.D. Pass, Kun Amy Professor Assistant Clinical/research expertise: M.D., 2002; UT Southwestern, Clinical Research Scholar, Clinical Sciences, 2009-2012 Scholar, Clinical Research 2002; UT Southwestern, M.D., training: Post-doctoral Hematology-Oncology, Pediatric Fellow, 2005-2006; UT Southwestern, Pediatrics, Resident, 2006-2009 disorders platelet other Education: Clinical Scholar, Clinical Research 2001; UT Southwestern, M.D., School, Norfolk, Medical Sciences, 2007-2010 training: Post-doctoral 2004-2007 Hematology-Oncology, Pediatric Fellow, 2004; UT Southwestern, pediatric other cancers and neuroblastoma relapsed for therapies novel Education: 2002 M.D., Memphis, Medicine, College of Tennessee, of 1996; University laude, training: Post-doctoral Fellow, Houston, Hospital, Children’s Medicine/Texas of College Baylor 2002-2005; Pediatrics, Cindy E. Neunert,Cindy E. M.D. Professor Assistant Clinical/research expertise: for Children, Perth, Western Australia, R Australia, Western Perth, Children, for 1992-1996; Bonfils Hematology-Oncology, Pediatric Fellow, Denver, Science Center, Health 1995-1996; The Children’s Hematology-Oncology, Pediatric Fellow, CO, Denver, Blood Center, 1996-1998 Pediatrics, Resident, CO, Denver, Hospital, Professor Assistant Clinical/research expertise: in sickle cell disease research outcomes Education: Timothy McCavit, M.D. McCavit, Timothy Associate Professor Associate Blood Disorders and Cancer for Center Clinical Director, Program Fellowship Hematology-Oncology Pediatric Director, Clinical/research expertise: Education: training: Post-doctoral 1987-1989; Our Lady’s Medicine, Internal Resident, Dublin, Hospital, Vincent’s 1986-1987; St. Resident, Dublin, Children, Sick for Hospital Patrick J. Leavey, M.D. Leavey, J. Patrick UT Southwestern/Children’s, Resident, Pediatrics, 2002-2005; UT Southwestern, Fellow, Fellow, UT Southwestern, 2002-2005; Pediatrics, Resident, UT Southwestern/Children’s, 2005-2008 Hematology-Oncology, M.D. Koh, Andrew Cancer Center the Simmons and Microbiology Pediatrics, Professor, Assistant Program Cell Transplantation Stem Hematopoietic Pediatric Director, Clinical/research expertise: host, Candida albica immunocompromised interactions host pathogen pathogenesis, Education: 1996 School, Boston, MA, M.D., Medical Harvard 1990; B.A., England, College, training: Post-doctoral Hospital Disease; Infectious Children’s Pediatric 1999-2000; Fellow, Pediatrics, Chief Resident, 2001-2004 Hematology-Oncology, Boston, Fellow, MA, Cancer Institute, Farber Dana and oncology Education: training: Post-doctoral Laura Klesse, M.D., Ph.D. M.D., Klesse, Laura Professor Assistant Program Neurofibromatosis Director, Clinical/research expertise: 104 Hematology-Oncology Pediatric Hematology-Oncology, 2005-2008 Clinical/research expertise Clinical/research Assistant Professor, Pediatrics and Biochemistry Matthew H.Porteus, M.D. Ph.D. Southwestern, Fellow, Pediatric Hematology-Oncology, 2006-2009 Post-doctoral training: Education: prevention of invasive fungal infections inchildren being treated for cancer expertise: Clinical/research Assistant Professor Stegner,Martha M.D. Chief Fellow, Pediatric Hematology-Oncology, 2007-2008 Pediatrics, 2001-2004;UTSouthwestern, Fellow, Pediatric Hematology-Oncology, 2004-2007; Post-doctoral training: 2010 Medicine, M.D., 2001; UTSouthwestern, ClinicalResearch Scholar, 2007- ClinicalSciences, Education: lymphoblastic leukemia expertise: Clinical/research Assistant Professor Tamra L.Slone, M.D. Pediatrics, 2004-2007;Fellow, Pediatric Hematology-Oncology, 2007-2010 Post-doctoral training: of Center Medicine, School Science Lubbock, M.D., 2004 Education: Texas Christian University, Fort Worth, B.A., 2000;Texas Tech University Health expertise: Research diseases expertise: Clinical Assistant Professor Tiffany Simms-Waldrip, M.D. UT Southwestern, Fellow, Pediatric Hematology-Oncology, 1987-1990 Resident, Pediatrics, 1983-1986;Research Fellow, Pediatric Hematology-Oncology, 1986-1987; Post-doctoral training: San Diego, M.D., 1983 Education: cell transplantation of use ameliorativedisease, therapies -hydroxyurea, celldisease insickle transfusion, and stem expertise: Clinical/research Director, Marrow Bone Failure and Hematology General Program Professor Zora R.Rogers, M.D. 1998-2001 Resident, Pediatrics, 1997-1998;UTSouthwestern, Fellow, Pediatric Hematology-Oncology, Post-doctoral training: UT Southwestern, M.S.C.S.,2008 Education: cell pain mortality and long-term outcome and novel thalassemia, of celldisease sickle causes of sickle expertise: Clinical/research Director, and Thalassemia Program Disease Sickle Cell Associate Professor Charles T. Quinn,M.D., M.S.C.S. Oncology, 1996-1999;California Institute of Technology, Pasadena, Fellow, 1999-2003 Dana-Farber Institute/Children’s Cancer Hospital MA,Fellow, Boston, Pediatric Hematology- Post-doctoral training: M.D., 1994 Program, Stanford, CA,Ph.D., 1994;Stanford University of School Medicine, Stanford, CA, Education: invitrodiseases, manipulation of hematopoietic stem cells,regulation of DNA damage repair RiceUniversity, Houston, B.A., laude, cum TX, 1999;UTSouthwestern, M.D., 2003 University of California,Berkeley, B.A. with honors, 1978;University of California, Texas Christian University, Fort Worth, B.S., 1990;UTSouthwestern, M.D., 1994; Harvard University, Cambridge, MA,A.B., 1986;Stanford University Neurosciences Auburn University, AL,B.S., 1997;University of Alabama at Birmingham of School Hematopoietic stem celltransplantatio Hematopoiesis, graft-versus-host disease University of Alabama Birmingham of School Medicine, Resident, UTSouthwestern/Children’s, Resident, Pediatrics, 1994-1997;Chief Children’s Hospital MA,Resident, Boston, Pediatrics, 1994-1996; UT Southwestern/Children’s, Resident, Pediatrics, 2003-2006;UT University of Angeles California Los Medical Center, Resident, University of California Southern Medical Center, Angeles Los County, : Novel approaches to gene therapy for children with genetic Clinicaloncology, adolescents and young adults with cancer, leukemia, complications Childhood of treatment of acute marrow Bone failure, general hematology, pediatric cell sickle hematology, pediatric General hemoglobinopathies, morbidity, n for malignant an d non-malignant Hematology-Oncology 105 Hanumantha Pokala, M.D. Pokala, Hanumantha Position: Current of University Professor, Assistant Science Center Health Oklahoma Research Interests: of pathophysiology and Epidemiology with in children infection fungal invasive cancer Best Oral Presentation at the Presentation at Best Oral Dr. Mark HatleyDr. won for the award (Pictured with Drs. Charles Rosenfeld and George Lister) 1st Annual1st Senior Fellows Research 2010 Dayin May General pediatric hematology and oncology General and pediatric hematology Leukemia, clinical trials in childhood acute lymphoblastic trials lymphoblastic in childhood clinical Leukemia, acute Benign hematology, bone marrow failure syndromes, thrombosis thrombosis syndromes, failure marrow bone Benign hematology, University of Virginia, Charlottesville, Resident, Pediatrics, 1999-2002, 1999-2002, Pediatrics, Resident, Charlottesville, Virginia, of University 1978-1981; Pediatrics, Resident, NY, York, New Hospital, Babies Yale-New Haven Hospital, CT, Resident, Pediatrics, 2003-2006; UT 2003-2006; Pediatrics, Resident, CT, Hospital, Haven Yale-New Position: Current of University Professor, Assistant Medicine College of Arizona Research Interests: in angiogenesis alterations Molecular Ph.D. M.D., E. Hatley, Mark Position: Current Hematology- Pediatric Instructor, UT Southwestern Oncology, Research Interests: cells in cancer Signaling Amanda B. Blair, M.D. Blair, B. Amanda Position: Current Science UT Health Professor, Assistant Antonio San Center, Research Interests: angiogenesis in alterations Transfusional M.D. Gupta, Puja Southern Methodist University, Dallas, TX, B.A., B.B.A., 1995; Texas Tech Tech 1995; Texas Dallas, TX, B.B.A., B.A., University, Southern Methodist Indiana University, Bloomington, B.A., 1974; Northwestern University, Chicago, IL, Chicago, University, 1974; Northwestern B.A., Bloomington, University, Indiana UT El Paso, B.A., 1996; Stanford University School of Medicine, CA, M.D., 2003 CA, M.D., Medicine, School of University Stanford 1996; B.A., UT El Paso, Completed June 2010 Completed June Post-doctoral Fellows Fellows Post-doctoral Chief Resident, 2002-2003; UT Southwestern, Fellow, Pediatric Hematology-Oncology, 2003- Hematology-Oncology, Pediatric Fellow, UT Southwestern, 2002-2003; Chief Resident, 2006 leukemia Education: 1978 M.D., training: Post-doctoral Hematology-Oncology, Pediatric Fellow, NY, York, New Hospital, Sloan-Kettering Memorial 1983-1984 Hematology-Oncology, Pediatric Fellow, 1981-1983; UT Southwestern, Naomi J. Winick, M.D. Winick, Naomi J. Professor Neuro-Oncology in Pediatric Professorship Foundation Lowe Investigator Principal Oncology Group Children’s Clinical/research expertise: Education: Education: 1999. M.D., Lubbock, University, training: Post-doctoral Jonathan E. Wickiser, M.D. Wickiser, E. Jonathan Professor Assistant Clinical Director Outpatient Clinical/research expertise: Cristina Tarango, M.D. Tarango, Cristina Instructor Clinical/research expertise: and hemastasis, vascular biology, the antiphospholipid antibody syndrome antibody the antiphospholipid hemastasis, vascular biology, and Education: training: Post-doctoral 2006-2009 Hematology-Oncology, Pediatric Fellow, Southwestern, 106 Hematology-Oncology are Contracts Specialist AnnMarie Fillmore, Administrative Associates Laura Clarke and Patricia Ellisor and Senior and Ellisor Patricia and Clarke Laura Associates Administrative Fillmore, AnnMarie Specialist Contracts are infrastructure the Southwestern who UT Hematology-Oncology research support members at team The Pediatrics program’s the in missions. education research participate and and hematologic and cancer disease Children’s with to children employees care provision the who assure of high-quality the and staff and Southwestern faculty UT the 150, between relationship aclosemore working and exists than The staff at UT Southwestern and Children’s who support Hematology-Oncology clinical care and researchnumber Clinical, Research andAdministrative Staff 2nd Year 3rd Year 1st Year 1st cancer of viralinfections infebrile children with Molecular diagnosticcharacterization Interests: Research M.D. Cost, Carrye using zebrafish models Molecular of biology germ celltumors Interests: Research Nicholas Fustino, M.D. leukemia central injury inchildren nervous with Late neurocognitive affects of acute Interests: Research Laborde, M.D.Carrie brain childhood tumor survivors Late complications metabolic of Interests: Research Cooksey,Raven M.D. oncology Quality improvement inhematology- Interests: Research Wilson M.D. File, cancer of asamodel childhood Clinicalhematology-oncology, zebrafish Interests: Research Kenneth M.D. Chen, Molecular immunology Interests: Research Scott Furlan, M.D. children with leukemia Thiopurine metabolism and toxicity in Interests: Research Amy Fowler, M.D. Intravenous iron therapy Interests: Research Plummer,Ellen M.D. biomarkers of cardiac injury inchildren Clinicalhematology-oncology Interests: Research Leger,Kasey M.D. hematology-oncology, palliative care Clinicalhematology- oncology clinical Interests: Research Chesley,Rachel M.D. Hematology-Oncology 107 Laboratory research in the division during 2010 was conducted conducted was 2010 during division the in research Research Laboratory Laboratory several – Drs.by Scott outstanding Cameron, physician-scientists Matthew Porteus, Andrew Mark Hatley Koh, and James Amatruda. AmatrudaDr. trained in zebrafish genetics with the world’s expert at Harvard and has established investigative a robust program in this area UTat these Each Southwestern. of local scientists has received or awards grants from theis principal R01 NIH recognition on of investigator for their outstanding and future accomplishments potential.presence The faculty these theof scientists on Hematology-Oncology bench has greatly visibility enhanced the division’s both locally and nationally. Effortsrecruit to to additional way are under the physician-scientists divisional new by brightened a prospect leadership faculty during 2011, and additional resources. Numerous clinicalNumerous cell studies disease, (sickle involving patients hematology hereditary spherocytosis, thrombosis, alsoimmune thrombocytopenia are being carried faculty by (ITP)) out trials many are and multi-center fellows; sickle to cell the by supported centers NIH.program The was comprehensive 10 by funded of the NHLBIone as participate in a clinical hospitals trials children’s of a select is currently group of consortium, one and Children’s nationally in a Sickle Cell involved Disease and Research Basic Translational Program initiated in April 2008. The division also the of Clinical Medicine-Hemostasis NHLBI-supported is a member Transfusion Trials Network. In addition to these multi-center studies, more than a dozen local investigator-initiated in progress. currently are or research 2010 during projects in completed hematologywere Hematology Oncology Each Hematology-Oncology faculty physician participates in joint clinical All Principal research faculty Investigator. Winick is the Naomi center’s for in projects, which Dr. particularly (COG), studies Group Oncology the Children’s involving therapeutic in-house of number a conducts in themembers COG, an division of are NIH-funded members division multi-institutional consortium cancer of research the COG, in research clinical to addition In centers. children with including innovative research cancer, programs in and lymphoblastic Phase acute I leukemia (ALL) and II trials with patients for advanced malignancies various of types. Other institutional research studies focus on alterations,genetic effects late in survivors, anxiety supportive and caredepression, and in cancer patients. Research Activities Research Other Children’s support staff support clinicnurses, Other registrationinclude medical Children’s and inpatient personnel, assistants, social pharmacists,workers, nutritionists, child life a childassociates, life an assistant, interpreter, a cancer registrar, a the in leadership an manager in outreach and personnel collaborating departments coordinator, administrative receptionist, a new-patient telephone provides Director, Senior Schmidt, Kaye therapy. physical and care pastoral as such working Wickiser with assure closely to and Jon effective the Buchanan, Drs.CCBD, George efficient, Patrick Leavey, and all safe of operation clinical activities. Barbara and Obert, Kathy Carlisle, Operations Director, Nursing Director, are also the team. leadership on CCBD Advanced practice nurses and nurse clinicians play a major role in the practiceAdvanced clinical nurses and role clinicians nurse a major play and research programs.programs These advanced-practice nurses in four sickleinclude cell disease transfusion two and in blood chronic stem cell therapy, twotransplantation, in survivorship, effects/cancer in late neuro-oncology, hemophilia/thrombosisone one in and nurses Three in four research,function generalin oncology. enrolling exclusively monitoring patients and with cancer diseaseand in hematologic investigative diverse protocols. The division’s clinicalresearch infrastructure The division’s primarilyThirteenbased is clinical Children’s. at research and associates three research nurses, managed Leah by Adix and Jenniferformatting, Evans, Southwestern’s handle data UT research analysis, protocol with and Children’s at Department design, IRB form data regulatory collection acquisition, and sample analysis.consent and HIPAA oversight, This Research Clinical the in counterparts with closely works team Cancer and Center Institutional Review Board. Administrative Assistants Leann Bryan,Stewart Kay research Drs.of and laboratory Michael Winemiller.The Matthew Porteus, Scott Cameron, MarkHatley and James Amatruda has 28 students,been supported by trainees and staff. research 108 Hematology-Oncology inpatient services (hematology, stem cell transplantation or oncology) during their rotations, which are two weeks in length length in weeks two are which rotations, or their oncology) (hematology, during transplantation stemcell inpatient services one of three members Various supervise consultations. providing and faculty patient care to coordinating addition in andresidents students medical teaching in participate attending physicians theThe throughouthospital. on floors other Tower in unit 24-bed adedicated in care Dand direct under hematologic and usually cancer disorders are inpatients with Children’s.at programs subspecialty largest of The CCBD theTwenty-fiveonePediatrics’ has Department of to forty Activities Clinical biology.vascular oncology, biology, immunology, stemcell molecular cancer and of hematopoietic transplantation, areas stemcell the whose major in lie interests faculty additional several on attention recruiting isfocused level, special divisional At the interact. fellows will and collaborations and further growth of the critical for enhanced allow will basic oncology research and mass clinical of in programs investigative and investigators Center’sCancer clinical on the campus with whom pediatric Texas. of the North faculty in Expansion NCI-approved only program the CCBD being the cancer in Center pediatric results program’s recent excellence, the receipt of Southwestern’s NCI by designation UT Comprehensive Simmons Cancer to explore laboratory To and research and the advance new areas. and investigative clinical maintain existing to strengthen faculty additional to recruit plans division the Second, program. Legacy ofdevelopment the growth and successful including strategies, diverse patient by outreach and creative base its large marketing and maintain must To first division world the unchanged. the goal, in — remains Hematology-Oncology programs this achieve and Children’s Southwestern UT at division’s pediatric finest establish — Thethe to objective one of program overall Long-range Research Goal Program members. faculty held by divisional NIH the from contracts and numerous to grants addition the other in are These (NCTCTRI). Initiative Research Translational and Clinical Texas Central Southwestern’s and of UT North part NIH-supported as award KL2 institutional by an were part supported in three and grants Investigators members 2010,were of R01 Principal during faculty three Foundation. note Of Armstrong Lance Foundation the and Carter G. Oncology, Amon the of Clinical Society Cancer, American Kids’ the Control Prevention, and Disease Children’s the Wipe Fund, Out Cancer Centers for the Administration, Services Resources and Health of the Bureau Health Child and Maternal includes the organizations other from funding agencies, NIH-supported to the addition In NHLBI. (NCI) Institute or Cancer National from grants primarily million, 2010 $3.4 during Hematology-Oncology to more in amounts than members Total support. for support faculty Southwestern research UT programs research peer-reviewed biochemistry, biology and grant receiving laboratory molecular in active have faculty division’s the of Three Research Funding Research (CRTI). Institute Training Clinical prestigious Hematology’s of Society American the attend to selected were faculty junior or fellows mentor. Dr. their as with George Buchanan disease For cell sickle seven on research consecutive pediatric years, their have appointed divisions other focused in formally Scholars Clinical other two Southwestern, at while Scholars UT Research or grant-supported Clinical CTSA KL2 members to have 25NIH 20 beenamong the oncology faculty Further evidence of the robust clinical research environment within the program is the fact that six hematology- support staff. research Hematology-Oncology clinical faculty, fellows and attracting successful, highly are results and hypotheses research present their fellows informally and at faculty which meetings research hemostasis-thrombosis. and Regular cancer, disease cell childhood sickle patient-oriented supporting in investigation grants peer-reviewed NIH through funded are many and Dallas, in positionsthese are at Children’s based of All members. staff research consistshematology of 19 –currently clinical oncology and components separate serving –with division the within infrastructure research clinical outstanding The decade. the past during grown substantially in Hematology-Oncology has program research The clinical Research Clinical Hematology-Oncology
109 on Outreach Buchanan activities George and Cristy spearheaded been Dr. by have Ecton, the Outreach Program Ms. Manager. efforts. marketing, relations, She also public serves and physician-relations a as liais the division’s for Ecton is responsible Outreach On September 25, 2010, we held for the year 12th consecutive for our highly held we successful 2010, 25, On September Continuing Medical course Education for primary care physicians, directed by Zora Dr. Rogers. More than 50 attendees benefitted from the five-hour-long Saturday morning and referring earlyamong afternoon reputation program.haveexcellent an continues to The CCBD consultative services. prompt its full-time A for physicians referral – new patient coordinator the staff Children’s at member – handles incoming calls and working schedules with appointments, closely a full-time the “referral doc,” faculty CCBD is available who immediatelyphysician handle as requests to well advice. as urgent answer and to questions provide A key component of the hematology-oncology program stem cell the of hematology-oncology is the transplantation hematopoietic A key program. component Twelve constitute marrow floor the thetransplant Hematology-Oncology of the 24 beds on D6 inpatient unit. These rooms contain high-efficiency particulate airfilters andunidirectional reduce to infection flow More air autologous risk. than 250 stem cell peripheral umbilical blood or and transplants marrow, allogeneic blood been performed since the cord have stem cell A national a new search transplant in for inception including 1992, during 27 program 2010. program’s director was successfully establishing is rapidly during He Andrew2009 Koh. the completed program Dr. with of the appointment excellence. as of a regional center fundraisingto with relationships referring and Formal and physicians. clinics monitors groups support outreach conducted three times four to Texas, a year. sickle cell included clinics division have by members in Tyler, Hematopoietic Stem Cell Transplantation Program Cell Transplantation Stem Hematopoietic The clinicalThe service is structuredarena in outpatient the nurses, teamsphysicians, around of research social workers and staff serving patients tumors, stem bone withhemophilia and sickleoncology, thrombosis, cell disease,generalhematology, brain and (After ACE) the Cancer cell tumors. cancer transplantation,Experience,or team Each follow-up meets long-term weekly to discuss care patient issues, protocols, research and administrative activities. Patients are also discussed weekly at multidisciplinary departmentalproblems all allow patient to for aware major of conferences staff relevant be to members cases are discussed team leukemia,to New follow-up a weeklyand decisions. contribute at tumor to solid and complex Board meeting. Cases Board meeting. involving brainTumor tumors are discussed Tumor a Neuro-oncology at each week or blood products as part of their regular outpatient management. During 2010 there were more than 20,000 outpatient outpatient 20,000 than more were there 2010 During management. Sixty patients seen are daily clinic, outpatient seventy-five to in staffedfourby or three full-time facultymembers and outpatient regular their of several these Many of fellows. marrow children aspiration, lumbar bone puncture, receive drug part and intravenous treatments as products blood or facilities outpatient visits in Children’s hematology-oncology Dallas to years has Hematology-Oncology and for Legacy. at are statistics Outpatient numbers. patient to with regards program outpatient medical subspecialty largest Children’s been Appendix. the in included Hematology-Oncology carries 1,000approximately formal out inpatient providing diagnostic each consultations year, evaluationsand of outpatient children with anemia, disorders. bleeding disorders, and other hematologic new patients 322 program with hasThe and record a cancer saw in 2010, time. given a at treatment active receiving patients cancer 400 than more 1,000Approximately additional their completed treatment patients have in thethe and nationally-acclaimed monitored and are followed “After Cancer Experience”program. 40 Unfortunately, young cancer patients reflecting theirlost during fight the fact 2010, that remains cancer most the cause illness death to of common due during childhood. statistic patient summary A ten-year as an is provided Appendix. campuses and, in particular, the number of new diagnoses. The CCBD CCBD The diagnoses. new of number the thethroughout clinical During the year. 2010 program grow to continued particular, in in total visits, outpatient both days at inpatient the Dallasand Legacy and, campuses be the to continues largest all – in numbers – of terms patient of medical Children’s. at programs subspecialty 110 Hematology-Oncology t James Amatruda, M.D., Ph.D. t t t t t t t t t t Buchanan, M.D.George positive reviews. provide and uniformly regularly 70 50and participate attendees Between physicians. care primary at aimed Southwestern UT at October each course Education Medical Continuing annual an offered has division the years twelve For recipientspast members awards. are the of teaching faculty Oncology Numerous division. Hematology- the within sub-programs of disease-oriented of each meetings the Club team and Tumor Oncology Rounds, Grand Tumor Neuro-oncology Board, Conference, Hematology Journal Case Board, Teaching week each to monthly, Hematology-Oncology conferences times Pediatric held including are several from accomplishments. and goals program and areas research patient populations, faculty resources, facilities, venue for describes that others, prospective as applicants well as developed has aWebfellowship program informative site, an The grant. training T32 institutional NIH an and Amgen Oncology, of Clinical Society Foundation, American the Children’s Wipe Cancer, Fund, Out Kids’ Baldrick’s Cancer St. Children’s,by (ACGME)the financially beensupported has and Education for Graduate Medical Accreditation Council by the isaccredited program training The forpriority division. the hematology-oncology, pediatric leaders in national isahigh development of this program, with the aim of training future initiated in 1984, with eleven enrolled in 2010. Continued completed Hematology-Oncology Fellowship the Program, foractivities the fellows. Fifty-eightindividuals have successfully of educational oversees array entire the Fellowship Program, Dr. Leavey, Patrick Hematology-Oncology of Director the the and residents. Coordinator, students Dr. Cox, for isresponsible Jennifer medical programs for developing monitoring teaching and division’s The of settings. Education avariety in lectures formal and groups, seminars one-on-one small through done interactions, is Teaching professionals. healthcare other and physicians, referring and care primary fellows, residents, students, the Division of haveHematology-Oncology in medical madeamajor commitment teaching to The faculty Presentations/Teaching Activities Therapeutics, Plenary Session, Therapeutics, Plenary BC, MarchVictoria, 2010 role “The BMPsignalingof in cell germ tumorigenesi November 2010 Management“Sickle Disease Cell Guidelines,” Washington, November DC, 2010 “Making aDifference,” American Association of Colleges OrganizationMedical of Student Representatives, Tumor Programs, Orlando, November 2010 “Management New Advances of Disease: Sickle Cell and New Controversies,” Florida Association of Pediatric and Exhibition, San Francisco, 2010 CA,October “Evaluation of aChildwith aPossible Bleeding Disorder,” American Academy of Pediatrics National Conference Meeting, Minneapolis, 2010 MN,October “Sickle Anemia:Understanding Cell and its Disease the Treatment,” National Marrow Donor Program Council Continuing Medical Education September 2010 TX, Course, Dallas, Bleeding Child:Clinical “The LaboratoryHistory and 2010 “Being Keen on Spleen,” the Visiting professor, University of Colorado, Aspen Research Conference, September “Iron-Too Little, Too Much and Why,” Pediatric Academic Meeting, Societies Vancouver, Canada, May 2010 “Diagnosis and Management of Iron Deficiency,” aspart Pediatric Hematology-Oncology, Montreal, Canada, April 2010 “Career Development Pathways inHematology-Oncology Research,” 23rd Annual Meeting, of American Society Orlando, FL,February 2010 “Pathophysiology Related Organ of Disease Sickle Cell Damage,” Marrow Bone Transplant Tandem Meeting, NHLBI-sponsored Herrick Symposium, MD, Bethesda, s,” Keystone Meeting on New Paradigms inCancer Values –When to Refer to aHematologist,” Annual of asymposium directed by Dr. Buchanan entitled Graduating fellow,Graduating Dr. discusses Gupta, Puja 1st Annual Senior Fellows Research Day 1st Fellows Research Annual Senior her research project atthe project research her May 2010 Hematology-Oncology 111 genesis Through Relieving Inhibition of the Ras Inhibition Relieving Through genesis and Quality of Life in a Pediatric Cancer Population,” Population,” Cancer in a Pediatric Life of Quality and VI North and South Hemophilia Meeting, Oklahoma Oklahoma Meeting, Hemophilia South and VI North 7th International Meeting on Carcinoma in Situ and and in Situ Carcinoma on Meeting 7th International lation Conditions and Anticoagulation,” One-Day One-Day Anticoagulation,” and Conditions lation es Luncheon, 52nd American Society of Hematology Society 52nd American Hematology of es Luncheon, ombosis in Cancer Patients, 23rd Annual Meeting, Meeting, Annual 23rd Patients, in Cancer ombosis “Bone Sarcoma - Role of the Interdisciplinary Team,” Grand Rounds, School of Health Professions, UT Professions, Health School of Rounds, Grand Team,” the Interdisciplinary of - Role Sarcoma “Bone 2010 January Southwestern, Adjustment Psychological in Promoting Potential “Hope’s Presentation) Oncology Society Psychosocial American 2011 (Poster (APOS), Anaheim, CA, February Canada, Vancouver, Directors, Program Fellowship for Forum PAS/APPD Annual Recruitment,” “Successful 2010 May and Topotecan Vincristine, Bevacizumab with of Combined (NSC 704865, BB-IND# 7921) “Feasibility Oncology Group Children’s (EWS)-A Sarcoma, Ewing Recurrent First with in Patients Cyclophosphamide “Role of Keratinocyte Growth Factor on the Virulence of Candida Albicans,” 10th Society American for Candida Albicans,” of the Virulence on Factor Growth Keratinocyte of “Role 2010 FL, March Candidiasis, Miami, Candida and on Conference Microbiology American Society of Pediatric Hematology-Oncology, Montreal, Canada, April 2010 Canada, April Montreal, Hematology-Oncology, SocietyAmerican Pediatric of Pediatric Practical Screening,” Thrombophilia of Benefits and Limitations It? Is or Power Is Itself “Knowledge 2010 September Children’s, CME Course, Hematology NewLA, Orleans, Meeting, Annual Foundation Hemophilia National YES,” Screening: “Thrombophilia 2010 November Traine Hematology-Oncology,” in Pediatric Career “A Education Annual Foundation States Genetics Mountain 1,” The Type Neurofibromatosis for Therapies “Current 2010 July CO, Denver, Conference, August Houston, Day, Education Neurofibromatosis Texas Neurofibromatosis,” for Therapies and Trials “New 2010 “Challenges for the Primary Care Provider: Hypercoagu the Primary Provider: Care for “Challenges 2010 April OK, City, Thr Catheter-related Diagnosis of and “Epidemiology FL, December 2010 Orlando, Meeting, Annual Cancer of the Testis, Copenhagen, October Denmark, 2010 the Testis, Cancer of Society Pediatric of SIOP/International childhood cell tumors,” germ of analysis genomic “High-throughput Boston, October MA, 2010 Childhood Session on Germ Cell Tumors, Satellite Oncology, Primary Seminar, Research Hematology-Oncology Pediatric Homeostasis,” in Vascular the Spleen of “Role October 2010 UT, Lake City, Salt Hospital, Children’s Development Scientist in Science, Pediatric Frontiers Cancer,” Cell Lung Non-small of Driver “MicroRNA-21: 2010 FL, March Tampa, Meeting, National Program Health School of UT Southwestern Convergence, Cancer,” Cell Lung Non-small of Driver “MicroRNA-21: 2010 April Rounds, Grand Professions Rounds, Grand Hematology/Oncology Pediatrics MicroRNA-21,” by Tumorgenesis K-ras-driven of “Modulation 2010 May Cancer Tumori Cell Lung Non-small Drives “MicroRNA-21 Selected Day, Research Senior Fellows’ 1st Annual Pediatrics, of Department Apoptosis,” Inhibiting and Pathway 2010 May Speaker, Ft. Center, Treatment Hemophilia Miami of University Events,” Thromboembolic “Venus Symposium, 2010 FL, March Lauderdale, Region Annual in Children,” Screening “Thrombophilia “Long-Term Side Effects of Childhood Brain Tumor Survivors,” Vanderbilt Ingram Cancer Center, Monroe Monroe Cancer Center, Ingram Vanderbilt Survivors,” Tumor Childhoodof Brain Effects Side “Long-Term 2010 TN, August Nashville, Lecture, Professor Visiting Vanderbilt, at Hospital Children’s Jr. Carell Francisco, San Meeting, Life Society of Quality (NTBS) Tumor Brain National Participant, and Attendee Invited 2010 CA, September TX, Worth, CME Course, Fort Symposium, Tumor Brain 2010 Pediatric Lecture, Invited Gliomas,” Grade “Low 2010 November “Genetic Models of Ewing’s Sarcoma,” Invited Speaker, Zebrafish Disease Modelling III: Cancer and Immunity Immunity and Modelling III: DiseaseCancer Zebrafish Speaker, Invited Sarcoma,” Ewing’s of Models “Genetic 2010 Boston, June MA, Models. tumorigenesis,” germ cell in of BMP signaling “The role Conference, Allergy Immunology and Pediatric Transplantation,” Marrow Post-Bone Reconstitution “Immune 2010 Dallas, TX, January t t t t Andrew Koh, M.D. Andrew Koh, t M.D. Leavey, Patrick t t t Laura Ph.D. Klesse, M.D., t t Janna Journeycake, M.D., M.S.C.S. M.D., Journeycake, Janna t t Mark E. Hatley, M.D., Ph.D. M.D., E. Hatley, Mark t t M.S.C.S. Shelley M.D., Crary, t t t t t t t t Victor M. Aquino, M.D. M. Aquino, Victor t Daniel C. Bowers, M.D. t t 112 Hematology-Oncology t t Buchanan, M.D.George Major Administrative Responsibilities orLeadership t t t Naomi J. Winick, M.D. t t Tamra L.Slone, M.D. t t t t Rogers, M.D.Zora t t M.D. Neunert, Cindy Member, Working Disease Sickle Cell Group, of Hematology American Society Associate Editor, Pediatric and Blood Cancer Former Chair and Executive Committee Member, Nominating Committee, of Hematology American Society Member, Planning Committee, Legacy Children’s Member, Clinical Program Development Committee, UTSouthwestern Member, ClinicalScholar K12/CTSA Program Committee, Selection UTSouthwestern Co-chair, Education Junior Session: Faculty Development, of Pediatric American Society Hematology/Oncology Director, Course Review of Pediatric American Society Hematology/Oncology Member, Editorial Board, Pediatrics inReview, American Academy of Pediatrics Member, Cancer Center ClinicalExecutive Committee Member, Dean’s Advisory Committee on ClinicalResearch Chair, Institutional #2 Board Review Program Performance Measures Project Member, External Advisory Committee, Texas Department of State Texas Health Services, Newborn Screening Co-chair, Guidelines Panel, Disease Cell Sickle NHLBI Member, Executive Committee, Research Disease Network GlobalSickle Cell Member, ScientificCommittee, Advisory Baldrick’sSt. Foundation Member, Medical Advisory Board, ITPFoundation, CT Darien, Chair, Protocol Committee, ClinicalResearch Review Network, Disease Sickle Cell NHLBI Director, Southwestern Comprehensive Center Sickle Cell Medical Director, Center for Cancer and Disorders Blood Director, Division of Pediatric Hematology-Oncology Orlando, 2010 FL,Dec “Successful Recruitment,” Annual Meeting of Americ the Presentation) for Developmental and Behavioral Pediatrics (SDBP) Annual Meeting. MA,September, Boston, 2010(Poster Role “The of Hope with Psychological Adjustment and Quality Lifeof ina CancerPediatric Population,” Society Presentation) Study,”(COG) of ClinicalOncolog American Society TX, NovemberTX, 2010 “New Leukemia Trials,” Pediatric Hematology-Oncology Grand Children’s Rounds, Cooks Hospital, Ft Worth, Rounds, Vanderbilt University, Nashville, TN,November 2010 of Children’s“Overview Group Oncology Protocols for Acute Lymphoblastic Leukemia,” Pediatric Oncology 2010 “Childhood Acute Lymphoblastic Leuk Conference, UTSouthwestern, February 2010 “Evaluation of Early Markers of Late Cardiotoxicity CancerSurvivors,” inChildhood Faculty Research Leukemia and Lymphoma Lone Star February Conference, 2010 Blood Society TX, Dallas, “Complications of Treatment the of Pediatric Acute Oncology, Director CMECourse and Speaker, September 2010 TX, Dallas, “Sickle Trait Cell 2010:What to Tell aFamily” and “Cases and Questions,” Practical Pediatric Hematology- York Methodist Hospital Symposium, Annual Disease Sickle Cell Brooklyn, NY, May 2010 “Organ Brain, Lung, Disease: inSickle Cell Kidney, Dysfunction Spleen and inBetween,” Everything Else New Ontario, Canada,April 2010 Symposium, of Pediatric American Society Hematology (ASPHO) Oncology 23rd Annual Meeting, Toronto, “Clinical Care and Patient Education,” Invited Speaker, Practical Care of Patient the with Fanconi Anemia Research 21stCentury, inthe Disease Sickle Cell Toronto, Ontario, April Canada, 2010 Moderator and Speaker, of Pediatric, American Society Hematology (ASPHO), Oncology 23rdAnnual Meeting: Modifying“Sickle Therapies: Disease Cell Hydroxyurea and Chronic Transfusion,” Seminar Organizer,In-depth ofCollege Georgia, Augusta, August 2010 “Immune Thrombocytopenic Purpura: Clinical and Aspects Management,” Pediatric Grand Rounds, Medical Thrombosis: Hemostasis and ThrombosisSociety Annual Research Meeting, Chicago, IL, 2010 April “Immune Thrombocytopenic Purpura: Clinical and Aspects Management,” Advances in Hemostasis and emia-Getting Closer,” Grand Rounds, Children’s Medical Center, January Lymphoblastic and Leukemia Lymphoblastic Lymphoma,” y Annual Meeting, Chicago, IL,June 2010(Poster an Society ofan Pediatric Society Hematology Program Directors, Hematology-Oncology 113 . Abstract Reviewer, American Society of Pediatric Hematology-Oncology, Program Committee Program Hematology-Oncology, Society American Pediatric of Reviewer, Abstract (SOHO) Section Hematology/Oncology on Pediatrics, of Academy American Committee, Executive Member, Safety Data Transplant Cell Sickle Bone Marrow Health,NIH-NHLBI of Institutes National Member, Ad-hoc Board (DSMB) Monitoring Consultant Services. Hemoglobinopathy Health Division Screening Newborn State of Department Texas Member, Program Committee, Abstract Reviewer, American Society of Pediatric Hematology-Oncology Society American Pediatric of Reviewer, Abstract Committee, Program Member, Children’s Committee, Credentials Chair, Children’s Committee, Advisory Medical Chair, Children’s Committee, Executive Medical Member, Children’s Committee, Physician Disruptive Member, Committee Grant Pathway Training Alternative Society American Hematology, of Member, on Conference 1st National CDC’s for Committee Planning to Representative SocietyAmerican Hematology, of Health in Public Blood Disorders Planning Committee Member, Harvesters Reaching the Nations Women and Children’s Health Care Center, Yei, Yei, Center, Care Health Children’s and Women the Nations Reaching Harvesters Member, Committee Planning Sudan South Society American Hematology of Communication, on Committee Member, Liaison Section Hematology-Oncology Pediatrics, of Academy American Committee, Nominating Member, Hematology-Oncology Society American Pediatric of Committee, Nominating Member, Clinical Director, Center for Cancer and Blood Disorders, Children’s Blood Disorders, and Cancer for Center Clinical Director, Program Fellowship Hematology-Oncology Pediatric Director, Hematology/Oncology Society American Pediatric, of Committee, Directors Program Fellowship Chair, Children’s Recruitment, Intern Pediatric Director, Orthopedic Oncology Clinic, Children’s Comprehensive Director, Committee Nominating ASPHO Member, Co-chair, Anticoagulation Task Force to Implement Joint Commissions New Patient Safety Guidelines-3E, Guidelines-3E, Safety Patient New Commissions Joint Implement to Force Task Anticoagulation Co-chair, CCBD Children’s Staff, Medical of Secretary/Treasurer Subgroup the Platelet/ITP of Chair Committee; Steering Five of Alliance Member, Children’s Committee, Executive Medical Member, Survivors) Tumor (Brain Feliz Camp Director, Medical Director, Hemophilia and Thrombosis Program, CCBD Program, Thrombosis and Hemophilia Director, Council Leadership Physician Baxter Healthcare Board, Advisory Member, and of Thrombosis Society International Hemostasis, Perinatal on Subcommittee Scientific Co-chair, Haemostasis Hematology Hemostasis, American of Societyon Subcommittee Scientific Member, Course Co-Director, Clinical Research Ethics Seminar, Center for Biostatistics and Clinical Science, UT and Biostatistics for Center Seminar, Ethics Clinical Research Course Co-Director, Southwestern Children’s Experience the After Cancer (ACE), Director, Medical Force Task Implementation CCBD EPIC Chairman, Division/CCBD Hematology-Oncology Pediatric of Division Coordinator, Education Member, Protocol Development Subcommittee of the Developmental Therapeutics Subcommittee, Children’s Children’s Subcommittee, Therapeutics the Developmental of Subcommittee Development Protocol Member, Oncology Group Group Oncology Children’s Committee, Scientific Therapeutics Developmental Member, Children’s Program, Care Palliative Pediatric Director, Medical Consortium Care Palliative Pediatric Texas Member, Founding Consortium Care Palliative Pediatric Texas Subcommittee, Research Chair, Member, Advisory Committee, Texas Cord Blood Bank Cord Texas Committee, Advisory Member, Blood and Pediatric Committee, Care Supportive Consortium Transplant Marrow Blood and Pediatric Member, Consortium Transplant Marrow National Infections, Blood Stream Catheter-Associated Nosocomial Eradicating for Committee Member, (NACHRI) Institutions Related and Hospitals Children’s of Association Chair, Germ Cell Tumor Biology Sub-Committee, Children’s Oncology Group Children’s Biology Sub-Committee, Germ Cell Tumor Chair, Zora M.D. Rogers, Cindy E. Neunert, M.D. Patrick Leavey, M.D. Leavey, Patrick Laura Ph.D. Klesse, M.D., M.S.C.S. M.D., Journeycake, Janna Daniel Bowers, M.D M.D. Cox, Jennifer Robert Bash, M.D. James F. Amatruda, M.D., Ph.D. M.D., Amatruda, F. James M.D. Aquino, Victor 114 Hematology-Oncology Tamra Slone, M.D. M.D. Neunert, Cindy Timothy McCavit, M.D. Koh,Andrew M.D. M.D., Klesse, Ph.D.Laura Mark E.Hatley, M.D., Ph.D. Paul Harker-Murray, M.D., Ph.D. Crary, M.D.Shelley James Amatruda, M.D., Ph.D. Buchanan, M.D.George /AwardsHonors Naomi Winick, M.D. Jonathan Wickiser, M.D. Tamra Slone, M.D. Clinical Research Scholar, Department UTSouthwestern, of ClinicalSciences, 2007-2010 Member, for Society Pediatric Research Clinical Research Scholar, Department UTSouthwestern, of ClinicalSciences, 2007-2010 Clinical Research Scholar, Department UTSouthwestern, of ClinicalSciences, 2009-2012 Member, for Society Pediatric Research Affiliate Neurofibromatosis Clinic–Children’s ScholarDedman inClinicalCare Outstanding OralPresentation Award, 1stAnnual Pe “Excellence inEducation,” ClinicalTeaching Award, UTSouthwestern Member, for Society Pediatric Research Outstanding Pre-clinical Teacher, 1st-yea America’s Top Edition Doctors, 9th FoundationArnold Gold Award for Humanism inMedicine, American Association of Medical Colleges Member, Constitutional Committee, Review Children’s Group Oncology Chair, Outcomes Subcommittee for Acute Lymphoblastic Leukemia, Children’s Group Oncology Member, Children’s Group Oncology ALLExecutive Committee Vice Chair, and Member Program of Services, of Board the Directors, Make-A-Wish Foundation of North Texas Outpatient ClinicalDirector, Center for Cancer and Disorders, Blood Children’s Member, of Hematology American Society Lymphoid Neoplasms Committee Medical Director, Camp camp), Esperanza (oncology Children’s r Medical Class,UTSouthwestern School Tumor Foundation Patient Education Grant diatrics Fellows Senior Research Day, UTSouthwestern Hematology-Oncology 115 1 6 9 3 8 3 7 5 8 7 9 7 0 2 0 7 3 11 54 13 17 15 92 13 82 47 13 69 10 15 94 123 471 182 290 2010 1,167 5 0 4 1 4 8 4 5 8 9 3 6 3 7 6 7 9 6 5 11 34 30 73 15 14 60 94 48 99 12 12 38 443 200 268 2009 1,116 4 2 6 4 4 4 7 6 7 4 1 1 2 5 5 11 58 13 13 15 84 12 12 10 48 48 17 71 17 55 84 278 476 259 2008 1,216 4 5 6 4 5 6 3 3 4 7 8 6 1 1 3 6 0 6 5 11 11 53 10 70 14 49 47 30 82 75 92 236 362 177 998 2007 9 9 6 8 4 8 7 2 4 9 3 7 3 9 2 1 3 3 6 3 38 16 74 13 20 38 18 62 12 46 70 229 277 184 842 2006 8 2 6 2 7 3 0 2 3 3 1 9 8 9 4 8 2 4 4 2 16 25 35 19 64 13 10 47 75 49 70 10 217 256 189 826 2005 4 7 9 2 4 1 9 5 5 8 5 8 5 4 5 7 0 1 8 11 36 15 73 31 12 61 16 12 21 39 13 61 217 157 738 209 2004 8 4 8 4 3 7 3 7 4 4 9 5 8 0 2 2 4 6 45 10 13 61 14 12 23 45 17 72 15 37 64 221 218 149 747 2003 8 2 4 6 2 1 0 2 2 6 9 2 8 6 6 0 3 3 11 11 34 57 12 18 30 14 53 14 23 51 172 259 136 689 2002 9 1 5 0 8 8 4 7 1 4 3 9 3 9 6 5 9 1 7 11 11 33 12 60 12 13 33 54 37 258 129 669 189 2001 HEMATOLOGY-ONCOLOGY PATIENT STATISTICS PATIENT HEMATOLOGY-ONCOLOGY *Neutropenia, idiopathic thrombocytopenic purpura, miscellaneous anemias, etc. Leukemia ALL AML Other Lymphoma Hodgkin’s Non-Hodgkin’s Solid Tumor System Central Nervous Wilms/Other Kidney liver Hepatoblastoma/other Osteosarcoma Ewing's sarcoma Rhabdomyosarcoma Other soft tissue tumors Neuroblastoma Retinoblastoma Other malignant tumors Germ cell tumors Histiocytosis Miscellaneous (borderline) Myeloproliferative disorders Total Neurofibromatosis Sickle Cell Disease Sickle cell anemia Sickle C disease Sickle beta plus thalassemia Sickle beta zero thalassemia Other hemoglobinopathies Total Coagulation Disorders A Hemophilia Hemophilia B Willebrand Disease Von Thrombosis Other Disorders Total Other Hematologic Disorders* Misc. Patient Evaluations New Patients Total New Patients 116 Hematology-Oncology Total Hematology Patients Oncology Patients Total HospitalDays- Total HematologyPatients OncologyPatients Hospitalizations -Legacy Total Hematology coagulopathies Hemophilia&relatedinherited Sicklecelldisease ACE -Young Adult BMT Neuro-oncology Oncology Outpatient UnitVisits - Total HematologyPatients OncologyPatients Total HospitalDays-Dallas Total HematologyPatients OncologyPatients Hospitalizations -Dallas Total Otherhematology coagulopathies Hemophilia&related Sicklecelldisease ACE -Young Adult BMT Neuro-oncology Oncology Outpatient UnitVisits -Dallas Total Allogeneic Autologous Stem CellTransplants Chronicapheresis transfusions Chronicerythrocyte Misc.hematologicdisorders coagulopathies Hemophilia&relatedinherited Sicklecelldisease ACE -Young Adult ACE -Peds Active Patients Legacy HEMATOLOGY-ONCOLOGY PATIENT STATISTICS Legacy 11,385 6,807 1,141 5,666 1,459 1,096 1,741 1,053 7,351 2001 168 589 363 445 299 496 17 13 4 11,433 6,441 1,453 4,988 1,475 1,036 1,791 1,143 7,116 2002 439 493 309 581 226 597 19 12 10 33 7 11,927 6,637 1,485 5,152 1,550 1,931 1,236 7,497 1,118 2003 432 486 293 484 157 613 56 9 5 4 12,300 1,305 5,808 1,689 1,239 1,794 1,459 7,571 7,113 2004 269 450 583 300 623 158 632 171 17 10 10 50 7 12,251 7,383 1,141 6,242 1,520 1,133 1,813 1,301 7,681 2005 155 626 101 289 387 553 337 566 16 10 49 6 12,111 @ 8,657 1,165 7,492 1,391 1,045 1,994 1,167 7,619 2006 346 475 337 519 500 157 669 131 303 17 54 11 6 6 12,931 8,540 1,795 6,745 1,431 1,010 2,219 1,243 1,232 6,533 2007 421 471 337 867 569 235 639 150 377 25 16 70 9 9 14,837 9,934 2,031 7,903 1,562 1,120 2,966 1,354 1,942 6,905 2008 863 255 659 155 359 184 202 442 452 342 876 27 18 10 72 24 14 58 9 9 14,719 1,207 9,837 1,741 8,096 1,812 1,247 2,783 1,802 1,902 6,493 2009 250 237 565 560 391 788 840 263 682 156 386 401 107 543 13 42 31 22 18 83 50 67 29 10 11 4 5 17,151 2,905 2,447 2,256 7,855 1,170 1,476 2010 400 400 888 260 678 184 454 439 793 53 81 44 66 26 22 97 0 4 5 Hospitalist Medicine 117 Hospitalist Medicine Hospitalist of Pediatrics at the University of Washington School of Medicine in Seattle, WA. Dr Dr WA. Seattle, the is UT Southwestern at Pediatrics of in Professor Associate Kalidindi, M.D., Vijay Medicine of earned He his medicalProgram Children’s. Medicine Hospital at degree Director for School his completed He from Osmania Medical University in College, 1981. Hyderabad Washington Detroit, in of residency Medicine in of pediatrics School in 1992 and pediatric University State cardiology fellowship Michigan/Wayne of in 1995, both Hospital at Children’s University the at arrivalMI. to Prior UT Dr Kalidindi at Southwestern was Clinical Associate Professor Pediatrics of Kalidindi has a distinguished as a clinician record towards and has made contributions evidencequalitybased practice and medical was improvement, recipient He education. theof recognition in physician award Michigan the and of teacher was of twice recipient graduate a is Dr Kalidindi programs. affiliated Washington of University at award year Medical Children’s of Leadership Center and Academy UT Southwestern Clinical Safety and Effectiveness Program. Dr Kalidindi of Pediatrics fellow the is a American of Academy theDallas Directors of Board at of is one Services He 1994. since Physician Children for Medical Center several committees the including Children’s of and is an active member Quality Committee. Dr Kalidindi medical program about development, is passionate and service. customer education Vijay Kalidindi, M.D. Vijay Director, Hospitalist Medicine Director, Faculty The group focuses four particular on The group areas:care, patient medical clinical education, research, advocacy. and The PediatricMedical Hospital MedicineThe program hassimilar shown at Children’s Center growth. Originating in 2002as a single service line with five UT pediatricSouthwestern facultymembers, program the has to grown twenty- six faculty eight service to covering members, up MedicalDallas lines Center Children’s Medical at and Children’s the is among largest It Legacy. and at clinicallyCenter in busiest the nation. Nationally the field of hospital medicine is relatively and Goldman in Englandyoung, a New Wachter Journal Medicine article. of Over the past decade, the hospitalists,with of number the introduction of the term “hospitalist”and hospitals using hospitalists, has grown making rapidly in the1996 of fastest one growing it specialties by in pediatrics. 118 Hospitalist Medicine Pediatrics, 2007-2010 Post-doctoral training: Education: expertise: Clinical Instructor Ayesha Ahmad M.D. Post-doctoral training: Science Center at Houston, Health M.D., UT 2003; B.A., 2007 and Education: expertise: Clinical Instructor Melissa Harlan, M.D. Post-doctoral training: 2007 Education: expertise: Clinical Instructor M.D. Durham, Megan Post-doctoral training: 2006 Education: expertise: Clinical Instructor Kenneth Chen, M.D. 2006 Post-doctoral training: Education: expertise: Clinical Professor Assistant Clifford N. M.D. Chen, Post-doctoral training: M.D., 2003 AL, Birmingham, Medicine, Education: expertise: Clinical Professor Assistant Bourland,M.D. Christina C. Post-doctoral training: Houston, M.D., 2007 Education: expertise: Clinical Instructor Ban, M.D. E. Kathryn UT Austin, B.S., 2002; UT Health Science Center Antonio, at Health San M.D., UT 2007 2002; B.S., Austin, UT The University of Cadiz, Spain, Study Abroad Certificate, 2002; UT Austin, B.S.E. B.S.E. UT Austin, 2002; AbroadCertificate, Study Spain, The Cadiz, of University M.D., at Branch Galveston, Medical UT 2003; B.S. TX, Sherman, College, Austin Southwestern, M.D., UT University, John 2002; Hopkins MD, B.S.E., Baltimore, Baylor University, Waco, 1998; Southwestern, M.D., B.A., UT TX, 2003 School 1999; of B.A., University TN, of University Alabama Sewanee, South, of the Science Center at University, Health Rice UT laude, 2003; cum Houston, B.A., TX, In-patient medicine In-patient In-patient medicine In-patient medicine In-patient medicine In-patient medicine In-patient medicine In-patient medicine In-patient Children’s Center, Medical National Resident, Washington, DC, UT Southwestern/Children’s, Resident, Pediatrics, 2007-2010 Southwestern/Children’s, Resident, UT Pediatrics, 2007-2010 Southwestern/Children’s, Resident, UT Pediatrics, 2006-2009 Southwestern/Children’s, UT Resident, Pediatrics, 2007-2010 Southwestern/Children’s, Resident, UT Pediatrics, UT Health Science Center at Houston, TX, Resident, Pediatrics, 2003- ScienceCenter at Houston, Resident, Pediatrics, Health TX, UT Southwestern/Children’s,UT Resident, 2003-2006 Hospitalist Medicine 119 University of Florida Health Science Center, Jacksonville, Florida Health of University Resident, Center, Science Johns Hopkins University, Baltimore, Pediatrics, Resident, MD, 2007- Hopkins Johns University, Pediatrics, Resident, UT Southwestern/Children’s, 2001-2004 Pediatrics, Resident, UT Southwestern/Children’s, 2000-2003 UT Southwestern/Children’s, Resident, Pediatrics, Resident, UT Southwestern/Children’s, 2002-2005 Pediatrics, UT Resident, Southwestern/Children’s, 2007-2010 Louisiana Shreveport, Health University Resident, State Sciences Center, In-patient medicine In-patient medicine In-patient medicine In-patient medicine In-patient medicine In-patient medicine In-patient medicine, pediatric critical care University of Florida, of Gainesville, University B.S., 2002; Medical Georgia, College of Augusta, University of Florida, of Gainesville, University Miami of University B.S., of School 1994; Texas A&M University, College B.S., Station, summa cum A&M University, 2003; laude, UT Health Texas of School University Temple Baltimore, B.S., MD, 1997; Hopkins Johns University, UT Austin, B.A. and B.S., 2007 2003; UT M.D., Southwestern, UT Program, Austin, 2002 B.A., UT Plan M.D., 1996; II Southwestern, Honors Louisiana State University, Shreveport, B.S., magna cum laude, 1981; Louisiana Shreveport, State B.S., Louisiana magna cum University, State 1981; laude, Pediatrics, 2006-2009 Pediatrics, Adrienne McMillan, M.D. McMillan, Adrienne Instructor Clinical expertise: Education: Health Medicine,University of Shreveport, School 1985 Sciences Center M.D., training:Post-doctoral Education: 2006 M.D., training:Post-doctoral Assistant Professor Clinical expertise: Jessica Lynn Lloyd, M.D. Lloyd, Lynn Jessica Jacksonville, Florida Health of and University Louisiana Center, Sciences State Pediatrics, 1985-1988; Pediatric Critical Shreveport, Health Fellow, CareUniversity Sciences Medicine, Center, 1988-1991 Eron S. Linver, M.D. Eron S. Linver, Assistant Professor Clinical expertise: Education: Medicine, 2000 FL, M.D., training:Post-doctoral 2010 Benjamin C.Benjamin Lee, M.D. Assistant Professor Clinical expertise: Education: 2007 M.D., Houston, at Science Center training:Post-doctoral Education: 2001 M.D., Medicine, Philadelphia, PA, training:Post-doctoral Jennifer Johnston, M.D.Jennifer Johnston, Instructor Clinical expertise: Instructor Clinicalexpertise: Education: training:Post-doctoral Allison Hsu, M.D. Hsu, Allison Laura Davidson Harn, M.D. Harn, Davidson Laura Assistant Professor Clinical expertise: Education: training:Post-doctoral 120 Hospitalist Medicine Pediatrics, 2005-2008 Post-doctoral training: City, M.D. Oklahoma 2005 of Medicine, Education: expertise: Clinical Instructor Amit Mehta, M.D. 2008 Post-doctoral training: 2005 M.S., DC, Education: expertise: Clinical Instructor Yolande Pengetnze, M.D. Post-doctoral training: Center,Sciences Texas Worth, Fort Medicine, of D.O., College Osteopathic 2003 Education: expertise: Clinical Professor Assistant Patel, D.O. M. Reina 2004-2005 Resident, Pediatrics, Charlottesville, University of Virginia, 2002-2004; Post-doctoral training: PA, Philadelphia, Medicine, M.D., 2002 Education: expertise: Clinical Professor Assistant Anna Seong-Hee Pak, M.D., F.A.A.P. Post-doctoral training: Center, Sciences M.D.,University LA, 2006 Health Shreveport, Education: expertise: Clinical Instructor Phuong T. Nguyen, M.D. Post-doctoral training: Galveston, M.D., 2006 Education: expertise: Clinical Instructor M.D. Roxana Narat, 2007 Post-doctoral training: 2004 1998; George’s St. M.S., TX, West University Grenada, Lake, School of M.D., Medicine, Indies, Education: expertise: Clinical Professor Assistant Kimberly D. Mulson,M.D. University of Yaoundé M.D., I, Cameroon, 1998; University, Georgetown Washington, Vanderbilt 2001; University, B.S., TN, College University of Nashville, Oklahoma Houston University, Baptist 1999; University B.S., Texas of TX, North Health School of 1996; MCP B.A., Hahnemann Charlottesville, University of Virginia, Tulane University/Newcomb 2001; B.S., State LA, New College, Louisiana Orleans, at Branch University, Medical UT Rice laude, 2002; cum Houston, B.A., TX, Old University, Dominion Norfolk, VA, 1992; B.S., University of Houston-Clear In-patient medicine In-patient In-patient medicine In-patient In-patient medicine In-patient In-patient medicine, asthma, family-centered rounds family-centered asthma, In-patient medicine, medicine In-patient medicine In-patient medicine In-patient Maimonides Medical Center, NY, 2005- Medical Brooklyn, Resident, Maimonides Pediatrics, University of South Florida, Tampa, University Residency, Florida, of 2004- South FL, Pediatrics, University of Tennessee Science Center, Health Memphis, Resident, UT Health Science Center Science 2003-2006 at Houston, Health Resident, Pediatrics, UT NY, Shore Resident, North University Pediatrics, Hospital, Manhasset, 2006-2009 Southwestern/Children’s, UT Resident, Pediatrics, UT Southwestern/Children’s, Resident, Pediatrics, 2006-2009 Southwestern/Children’s,UT Resident, Pediatrics, Hospitalist Medicine 121 In-patient medicine, orthopedic infections Goryeb Children’s Hospital/Atlantic Health, Morristown, Hospital/Atlantic NJ, Goryeb Children’s South of Florida St. FL, Petersburg, University Pediatrics, Resident, Rainbow & Babies Children’s Hospital, Cleveland, OH, Resident, Resident, Cleveland, Hospital, OH, Rainbow Children’s & Babies Vanderbilt University Medical Center, Nashville, Medical University Center, TN, Vanderbilt Resident, Pediatrics, UT Resident, Southwestern/Children’s, 2007-2010 Los Chaguaramos, Central Universidad de Venezuela, Caracas, Medical South of Carolina, University 2005-2007; Resident, Charleston, In-patient medicine In-patient medicine In-patient medicine In-patient medicine In-patient medicine In-patient medicine University of Ghana, of Ghana University of B.Sc., Legon, Medical University 1999; School, Grenada, West University, TX, B.S. St. George’s 1998; Waco, University, Baylor Massachusetts Institute of Technology, Cambridge, MA, B.S. UT 1999; Massachusetts Technology, Institute of Tulane University, New Orleans, New LA, Arkansas B.S., of 2003; University the University, for Tulane Los Chaguaramos, Central Universidad de Venezuela, Caracas, 1989 M.D., Semester at Sea, Semester at Program, Institute Shipboard Education, Study Abroad for 2002, Texas A&M University, College Station, B.S., College Station, magna cum 2000; A&M laude, University, Texas UT Health Resident, Pediatrics,Resident, 2006-2009 2004-2007 Bharath M.D. Thankavel, Instructor Clinical expertise: Education: Health, Public of Baltimore, School Hopkins 2003; Johns Bloomberg Ch.B., M.B., Korle-Bu, 2005 M.P.H., MD, training:Post-doctoral Education: 2004 M.D., Indies, training:Post-doctoral Instructor Clinical expertise: Education: 2003 M.D., Southwestern, training:Post-doctoral 2003-2006 Pediatrics, M.D., M.P.H. Tetteh, Shirley Karthik Srinivasan, M.D. Karthik Srinivasan, Assistant Professor Clinical/research expertise: Leticia Shanley, M.D. Leticia Shanley, Instructor Clinical expertise: Education: 2005 M.D., San at Center Antonio, Science training:Post-doctoral DC, Pediatrics, Washington, National Senior Resident, Medical 2007-2008 Children’s Center, Luis Seguias,Luis M.D. Assistant Professor Clinical expertise: Instructor Clinicalexpertise: Education: Medical Sciences, Little 2007 M.D., Rock, training:Post-doctoral Education: training:Post-doctoral Catherine Robben, M.D. Robben, Catherine Pediatrics, 2007-2010 Pediatrics, Fellow, de Ninos, Hospital San Berardino, Pediatrics,Resident, Venezuela, 1990-1993; Fellow, NY, Albert 1994; Einstein York, Medicine,Pediatric College New of Nephrology, Miami- of University Pediatrics, Resident, 1996-1997; 1994-1996; Pediatric Nephrology, 1997-1998 Pediatric Nephrology, FL, Memorial Hospital, Jackson Fellow, Jennifer Rammage, M.D. Rammage, Jennifer Instructor Clinical expertise: Education: TX, B.A., Houston, 2003; 2007 UT M.D., Southwestern, Rice University, training:Post-doctoral 122 Hospitalist Medicine have engaged in a number of research endeavors, some collaborative with other disciplines. Faculty members have Faculty have anumber of disciplines. endeavors, other engaged research in some with collaborative and interests members develop clinical related one faculty Medicine to their Hospitalist or more of expertise areas Research Activities nurse practitioners. including physician extenders, and to faculty, residents lectures ,students, several and meetings hadposterpresentations national in faculty Division programs. advocacy include resident and reports morning activities other and recruitment intern the in participate hospitalists Several physicians. resident for isavailable elective our Ahospitalist education well. as nursing in participate rotations. faculty elective Hospitalist outside doing from programs trainees School and Medical Southwestern UT from students medical year third and Baylor Charlton UTSW), Smith, and Methodist Garland, Peter (John programs local from interns practice family Southwestern’s program, residency UT from categorical residents teach for residents. and to createstudents Faculty our novel expected opportunities are School educational and appointments Medical Southwestern at hold UT faculty hospitalists Children’s. Southwesternand of UT All programs educational the in participate members actively faculty Medicine Hospitalist duties, clinical to their addition In EducationMedical suburb Children’s the opened resident in 2008, at pediatric In physicians. Legacy and students medical including learners, of levels several with service teaching a prototypical resembles second The coverage. attending on-site reliesfirst 24-hour, on The campus. 7days week, thea Dallas theat year during staffed of services types two are floor. pediatrics There general to the who admitted are Louisiana Northern and Texas, East Oklahoma and Southern Texas, North center patients Children’s in for North patients pediatric from medical draws tertiary largest the As Patient Care Pediatrics, 2006-2009 Post-doctoral training: Southwestern, M.D., 2006 Education: Clinical expertise: expertise: Clinical Instructor Kathleen Vandiver, M.D. Texas UT University, A&M 2000; Station, College B.S., In-patient medicine In-patient the attending physician. attending the hospitalist and consultant isthe where subspecialist the service hospitalist include implemented creationwas plans of 2009, and asubspecialty in unit care asthma An care. family-centered and practice evidence-based for of patients care through quality highest provide and complexity the varying conditions with of encounter medical range awide Faculty service. one teaching and twoLegacy) and at (five Dallas at services up toare seven hospitalist representsmonths, which coverage of over 100 patient aday, beds there winter peak the During months. summer the during service teaching andtwo Legacy) and oneat at Dallas (three services fiveare hospitalist There hospitalists. by exclusively 24/7 staffed unit stay short a of creation year. the New developments include throughout change program our in Since patient seasonally, census number varies the of hospitalist services there. of Plano, Texas, on-site 24/7 model isutilized the and attending UT Southwestern/Children’s, UT Resident, Hospitalist Medicine 123 Hospitalist Legacy Liaison for Program Hospitalist Legacy Liaison for Program Liaison, Unit Physician Short Stay Floor Physician Liaison Physician Floor conferences M&M Coordinator, Liaison, Pediatric Clerkship Program AAP Society Hospital and Medicine Author, of and Module Member Academic Pediatric Group Working Program Curriculum Float Directors’ National Night and Journal Liaison, Club UT Hospitalist Southwestern Division Hospitalist Representative, Antibiotic Stewardship Committee Antibiotic Hospitalist Representative, Liaison Physician Floor conferences M&M Coordinator, Hospitalist Liaison for CommunityHospitalist Liaison for Relations Electronic Medical Record EPIC Liaison for Hospitalist Legacy Liaison for Program Liaison, Unit Physician Short Stay Medical Association Health, Committee Texas ChildChair, on and Adolescent Hospitalist liaison, Pediatric Residency Program Interns and for Faculty Medical Mentor Students Liaison for GlobalLiaison Health for Core clerkship teaching award teaching clerkship Core Awards and HonorsAwards Christina Bourland Katie Vandiver Katie t t Bharath Thankavel t t Karthik Srinivasan t Robben Catherine t Shanley Leticia Kim Mulson t t Amit Mehta t t t LeeBenjamin t Adrienne McMillan Melissa Harlan t Jennifer Johnston Megan Durham t Chen Clifford t t Christina Bourland t Ayesha Ahmad Ayesha t BanKatie Major Administrative or Leadership Responsibilities Major Administrative Many hospitalists administrative play our program towards which development: contribute and roles leadership Hospitalists participate in a number of hospital committees in order to improve both the efficiencythe care patients. Hospitalist of faculty in regional a presence and have nationaloforganizations Medical the as such hospital Texas and American PediatricPediatrics Society, of and Society Academy they Hospitalist Texas Association, Medicine of where the health for advocate our children. of Advocacy partnered with colleagues in Orthopedics to standardize the approach to management of bone and joint infections, infections, joint and bone of management to approach the standardize to Orthopedics in colleagues with partnered with the purpose service and morbidity reducing length stays. Hospitalist of in-patient in-patient also of serves asa site family-centered of rounds, that an implementation prospectively innovative andfor approach directly incorporates the andparents into patients discussion their of medical issues plans. and management theHospitalists of formulation participate in several quality initiatives pertaining care inpatient to including discharges, patient and are in process the of faulty research sets Some and pathways. members’ order several evidence-based, developing of computer-based interests include quality initiatives, bone infections, electronic medical record, national at meetings. information and presentations publications based practice. include Hospitalist accomplishments technology and evidence 124 Hospitalist Medicine Infectious Disease 125 for more than 40 years. than 40 more for Jeffrey Kahn, M.D., Ph.D., Professor of Pediatrics and Microbiology, is DirectorPediatrics of Professor and Microbiology, Jeffrey Ph.D., Kahn, M.D., theof Pediatric Infectious Disease program the and Sarah holds M. and Charles E. Chair Seay in Infectious Pediatric Diseases. was recruited He Yale from in 2009 studied human May he University discovered viruses. where newly Dr. report to was States clinical laboratory the the United first in Kahn’s group the features, and epidemiology features human genetic of metapneumovirus, human coronavirus and HKU1 NL63, and human bocavirus.new These viruses are respiratory tract associated with and disease lower upper in infants and Kahn children.young Dr. earned PQ, Montreal, his B.S.McGill at University, New Canada, of degrees University from State and and his Ph.D. in M.D. 1982 in Microbiology His Ph.D. Health Brooklyn at Center Science in 1991. York, thefocused on molecular vaccinia of biology virus, the virus used in the smallpox performed vaccine. his He internship and in residency Pediatrics at and served 1994 to as Chief in Hospital Connecticut 1991 from Haven Yale-New Resident of Pediatrics at the newly opened Children’s Hospital at Yale-New Kahn his Pediatric Infectious Dr. Yale completed at DiseaseHaven. Fellowship afterYale. joined he which faculty histhe Among at from 1995-1998, University InfectiousDisease Jeffrey Kahn, M.D., Ph.D. Jeffrey Kahn, M.D., Director, Pediatric Infectious Disease Pediatric Director, The division has provided an active infectious disease consultation service an active provided diseaseinfectious consultation has The division Faculty As a consultative service, faculty in and Pediatric fellows Infectious Disease interact with all divisions in the department and assist in children the of management with a variety underlying of medical problems. internationally. The faculty is recognized worldwide as leaders in many areas of infectious diseases and as principal principal as and Faculty in Pediatric Infectious Disease alsodiseases has been actively in engaged clinically than more research for applied infectious of areas many in leaders as 40 years. Results their of clinical-worldwide many forums at nationally research and are laboratory-based presented and recognized is faculty The internationally. andresearch international domestic efforts The of of collaborative research projects. investigators the division are a wide by varietysupported including sources the Institute of Allergy National of and Infectious Disease (NIAID), the Health and Resources the Services Institute Child (NICHD), National of Health and Human Development Administration and several as well as (HRSA) foundations, through grants and contracts the from pharmaceutical industry. The Division of Pediatric than more 40 for years,service with Children’s than and consultation for care more to 700 infants and children Infectious Disease Division facultyeach year. direct and manage the infection an program Children’s active at control ambulatoryat UT Southwestern hasservice children for withinfectious diseases, childrenprovided and HIV-exposed including and a large clinic HIV-infected for an active In theseadolescents. clinics, and medicalinfectious residents fellows, students are trained in complicated the of management and conferences rounds, diseaseconsultations, of form in the is clinical training This pediatrics. in diseases infectious consultation infectiousoutpatient disease and HIV completed from 23 different countries 96 physicians clinics. have 1965, Since training training fellowship inthe division’s these of program individuals percent and 75 approximately have Many graduates hospitals the universities worldwide. academic at of program appointments and children’s are chairs directorsor academic of programs. accomplishments, Dr. Kahn distinguished Dr. received accomplishments, research, clinical and has and received teaching Yale at awards research funding from the Institutes National Health, of the American Lung Association, and the American Heart others. among Association, 126 Infectious Disease Pediatric 2004-2008 Infectious Disease, 1997-2000; ChiefResident, Pediatrics and Medicine, 2000-2001;UTSouthwestern, Fellow, Post-doctoral training: 2010 Medicine, PA, D.O., 1997,UTSouthwestern, ClinicalResearch Scholar, 2007- ClinicalSciences, Education: Research expertise: Research expertise: Clinical Assistant Professor Monica Ardura, D.O. Investigator, National Institutes of Health, 1966-1968 Pediatrics, 1962-1965;UT Southwestern/Chi Post-doctoral training: College, New York, NY, M.D., 1962 Education: expertise: Research expertise: Clinical GlaxoSmithKline Distinguished Professorship of Pediatric Infectious Diseases Professor George H.McCracken, Jr., M.D. Public Health Research Institute (PHRI),Newark, NJ, Fellow, Biomedical Studies, 1990-1995 Post-doctoral training: Israel, Ph.D., Biochemistry, 1986 Education: expertise: Research Instructor Ruth Levitz, Ph.D. Fellow, Pediatric Infectious 1999-2003 Disease, Resident, Pediatrics, 1995-1998; ChiefResident, Pediatrics, 1998-1999;UTSouthwestern, Post-doctoral training: State University Medical Center, Shreveport, Ph.D., 1993;M.D., 1995 Education: processesof clinical disease expertise: Research expertise: Clinical Immunology graduate program faculty Assistant Professor, Pediatrics and Internal Medicine A.Gill,Michelle M.D., Ph.D. Pediatric 2007-2010 Infectious Disease, Children’s Hospital, Christi, Corpus Resident, Pediatrics, 2005-2007;UTSouthwestern, Fellow, Resident, Pediatrics, 2001-2003; ChiefResident, 2003-2004;Texas A&MUniversity/Driscoll Post-doctoral training: Education: expertise: Research international adoption medicine expertise: Clinical Assistant Professor Carla M.D. Garcia, Southwestern, Fellow, Pediatric 2000-2003 Infectious Disease, Post-doctoral training: Education: expertise: Research expertise: Clinical Interim Director, UTSouthwestern ClinicalHIVFellowship inSouth Africa Director, ARMS(AIDS-Related Clinic Medical Services) Assistant Professor Theresa M.D. Barton, Ursinus College, PA, Collegeville, B.S., 1994;Philadelphia College of Osteopathic Facultad Medicina Universidad deVenezuela, Central M.D., 2000 Smith College, Northampton, MA,A.B, 1993; UTSouthwestern, M.D., 1997 Williams College, Williamstown, MA,B.A., University 1958; Cornell Medical Hebrew University, Jerusalem, Israel, 1974;Tel B.Sc., 1972;M.Sc., Aviv University, Louisiana State University, Shreveport, B.S., laude, summacum 1988;Louisiana Pediatric infections infectious diseases, inimmunocompromised hosts Pediatric immunology infectious diseases, Pediatric infectious virallower disease, respiratory infections, tract Pediatric HIVinfection, infectious health pediatrics global diseases, Pediatric meningitis, infectious respiratory diseases, infectious diseases Immunobiology of human ce dendritic Infections inimmunocompromised hostsand related clinical trials The epidemiology Theepidemiology invasiveof Dallas in disease pneumococcal Biotechnology, discovery, drug respiratory signaltransduction viruses, Viral lower respiratory infections, tract particularly rhinoviruses Long-term outcomes of HIVinfection pediatric Penn State Geisinger Health System, Danville, PA, Resident, Pediatrics, Tel Aviv University, Israel, Fellow, Biological Chemistry, 1986-1989; University of Arkansas for Medical Little Intern Rock, Sciences, and Cornell UniversityCornell Medical College, New York, NY, Resident, Universidad deVenezuela/Hospital Central Universitario deCaracas, UT Southwestern/Children’s, Resident, Pediatrics, 1997-2000;UT ldren’s, Chief Resident, Pediatrics, 1965-1966; lls and role their pathogenesis inthe Infectious Disease 127 Completed June 2010) June Completed ( Kenneth Chen, M.D. Chen, M.D. Kenneth Position: Current Hematology-Oncology Pediatric UT Southwestern Fellowship, Research Interests: nutrition and growth child HIV, Pediatric Completed Sept. 2010) Completed ( Completed April 2010) April Completed Children’s Hospital of Pittsburgh, PA, Resident, Pediatrics, 1974-1977; Pediatrics, Resident, PA, Pittsburgh, of Hospital Children’s University of Minnesota Medical School, Minneapolis, Resident, Resident, School, Minneapolis, Medical Minnesota of University 1981-1984; Pediatrics, Resident, PA, Pittsburgh, of Hospital Children’s Yale University/Yale-New Haven Children’s Hospital, New Haven, CT, CT, Haven, New Hospital, Children’s Haven University/Yale-New Yale Congenital, perinatal and neonatal infections with focus on congenital congenital focus on with infections neonatal perinatal and Congenital, Community-acquired MRSA infections, healthcare associated infections associated healthcare MRSA infections, Community-acquired Management of osteomyelitis, mechanisms of antibacterial resistance, resistance, antibacterial of mechanisms osteomyelitis, of Management Gram negative infections; medical education infections; negative Gram Neonatal and congenital infections congenital and Neonatal Pediatric infectious diseases infectious Pediatric Pediatric infectious diseases, control infectious infection Pediatric Pediatric infectious diseases, infectious zoonoses Pediatric Erin Scheideman, M.D. Erin Scheideman, M.D. Position: Current Southwestern UT General Pediatrics, Instructor, Research Interests: development staff education, Medical Lana ( Lee, M.D. Position: Current Hopkins Fellowship, Medicine Adolescent Johns Research Interests: hepatitis viral world, HIV/AIDS in the developing University of Pennsylvania, Philadelphia, B.A., 1970; Boston University School of School of 1970; Boston University B.A., Philadelphia, Pennsylvania, of University Seton Hall University, South Orange, NJ, B.S., 1977; University of Pittsburgh School Pittsburgh of 1977; University B.S., NJ, Orange, South University, Hall Seton University of Minnesota Medical School, Minneapolis, B.S., 1952; M.D., 1954 1952; M.D., B.S., School, Minneapolis, Medical Minnesota of University University of Iowa, Iowa City, B.S., 1986; (Oxon) Rhodes Scholar, Oxford Oxford Rhodes Scholar, (Oxon) 1986; B.S., City, Iowa Iowa, of University Clinical Fellowship in South Africa in South Clinical Fellowship Post-doctoral Fellows Fellows Post-doctoral Professor Clinical expertise: Jane Siegel, M.D. Jane Siegel, Research expertise: Research expertise: Education: 1974 MA, M.D., Medicine, training: Post-doctoral Disease, Infectious 1977-1979 Pediatric Fellow, UT Southwestern, Pablo J. Sanchez, J. M.D. Pablo Professor Clinical expertise: syphilis and congenital CMV infections, gentamicin nomogram and validation and nomogram gentamicin CMV infections, congenital and syphilis Education: 1981 M.D., PA, Medicine, of training: Post-doctoral John D. Nelson, M.D. Nelson, John D. Emeritus Professor Clinical expertise: Research expertise: in children pneumonia community-acquired children, in arthritis reactive and suppurative Education: training: Post-doctoral 1957-1959; Pediatrics, Resident, 1954-1955; UT Southwestern/Children’s, Medicine, Internal Disease, Infectious 1959-1960 Pediatric Fellow, UT Southwestern, 1984-1986; UT Neonatology, Fellow, NY, York, New Center, Medical Columbia-Presbyterian Disease, Infectious 1986-1988 Pediatric Fellow, Southwestern, Research expertise: Jeffrey McKinney, M.D., Ph.D. M.D., McKinney, Jeffrey Professor Associate Director Education Resident Clinical expertise: Education: City, Iowa Medicine, of College Iowa of 1988; University B.A., Kingdom, United University, 1995 Ph.D., and M.D. training: Post-doctoral Pediatrics Fellow, CT, Haven, New University, Yale 1995-1998; Pediatrics, Resident, and Intern 1998-2001 Biology, Developmental and Cellular Molecular, and 128 Infectious Disease populations and neonatal infections. populations infections. neonatal and different in infections theMRSA epidemiology and of viruses human emerging newly infections, influenza and responses to RSV cell dendritic HIV/AIDS, of immunobiology the infections, asthma, nosocomial and infection pulmonary between link (RSV), the infections respiratory and pathogenesis agents, of meningeal of antimicrobial safety and pharmacology, efficacy clinical meningitis, bacterial diarrhea, as involves division suchareas the in Research Research Activities Data Specialist Techasaensiri,Benyachalee Clinical Post-doctoral Trainee Clinician Soriano-Fallas, Alejandra Data Specialist Clinical Sanchez, Adriana Bajwa, ResearchGagan Associate Banchereau, Assistant Romain Research ResearchClinical Staff 1st Year 2nd Year 3rd Year JuneCompleted 2010 and congenital syphilis HSV -Utility of HSVPCRinneonatal blood -Reverse-syphilis maternal screening disease infections Diagnosisand treatment of congenital Interests: Research Joseph Cantey, M.D. inenteric bacteria Molecular mechanisms of pathogenesis Interests: Research Thomas Fox, M.D. acute otitis mediainchildren on Moraxella catarrhalis; pathogenesis of infection of respiratory epithelial cells Effects of Respiratory virus syncyctial Interests: Research Amanda Evans, M.D. RSV Role of gamma interferon inmurine infection Interests: Research Tulsa, OK (private practice) TheChildren’s Hospital at Saint Francis, Current Position: Michael Chang, M.D. hnvrsifcin soitdwt bronchiolitis infections Rhinovirus associated with Interests: Research UTSouthwestern Disease, Assistant Professor, Pediatric Infectious Current Position: GarciaCarla M.D. Eduardo Lopez Medina, M.D.Eduardo Lopez interactions inchildren; immune bacterial-viral-host Epidemiology of diseases pneumococcal Interests: Research Alejandro Jordan-Villegas M.D. lncladimnlgc etrso Rhinovirus Clinicaland immunologic- features of infection Interests: Research Margaret Trost, M.D. gastrointestinal interactions aeruginosa inthe tract albicans Candida and pseudomonas Interests: Research Infectious Disease 129 Division Director. Division to Dr. William Scott,to Dr. Pediatric Cardiology 1st Annual SeniorAnnual Research Fellows 1st Day Graduating fellow Michael Chang explains his research At a weekly Wednesday morning a weekly InfectiousAt Wednesday Disease lectures Conference, and discussions in open are which held reports least twice at each infectious and their discussed. disease are presented work-in-progress present topics Fellows casesyear Journal where the at on clinical Club, service are thoroughly discussed. In the addition, faculty members participate actively in the teaching and students, through of fellows residents lectures in the annual Department course; Microbiology formalof and informal discussions with and during visitors students, fellows residents, daily including the each year, monthly Children’s at rounds; lectures conferences many noon at students to and residents lecture; and consultation ambulatory Us” inpatient Among “Bugs clinic service in and talks ARCH; the at annual Haltalin Seminar. Children’s-sponsored service, or the HIV/AIDS clinic During this rotation, trainees trainees rotation, this During clinic Third- fourth-year medicaland students pediatric and residents HIV/AIDS can in the work elect general to Infectious Disease the inpatient or service, in infections of management and diagnosis with experience gain infantsneonates, and children, familiarity with the rationale for antimicrobialselection of agents, and to insight issues into related practicesinfection-control in hospitalized rotation The patients. in the HIV clinic offers experienceof children in management withand adolescents HIV infection, as well as prophylaxis and testing infants of HIV to born mothers. positive trainees are provided a background in laboratory techniques techniques laboratory in background Activities Presentations/Teaching a provided are While in thePediatric Infectious Disease program, fellowship trainees of classical microbiology, immunology and molecular biology; experience in application of the scientific method to clinical and laboratory research; and an opportunity to develop competence in diagnosis infectious of and management diseases. Dr. CarlaDr. Garcia joined the International Adoption Medicine Clinic to open at the Children’s Medical Center at campus. Legacy The division is responsible for an active infectious disease ambulatory clinic at Children’s, where follow-up carefor is activean infectious responsible follow-up The is division disease where ambulatory clinic Children’s, at 120 approximately children to initiallymanages withprovided infections were who complicated also managed and those have to who as in-patients division The community. the in physicians practicing by clinic the to referred been children asHIV-infected well and as adolescents an additional infants of group and children young with perinatal HIV exposure. Clinical Activities Consultations in the pediatric care and neonatal units intensive Parkland at (both Dallas and Children’s and Legacy patients with involve campuses) inherited acquired or immunodeficiency, includingreceiving patients organtransplantation, cancer, therapy marrow for immunosuppressive and bone stem cell transplantation; inflammatory diseaseand infantsdisorders; bowel rheumatologic and childrenand with a varietywide classic of as well as unusual infectious disease problems. Dr. Garcia with works Dr. viral respiratory tract infections in children, young particularly RSV and rhinoviruses. She studies the clinical has work characteristics, Garcia’s disease and Dr. differences host severity, in immune-response. research in respiratory for viruses. the by been supported MedImmune Grant Award Fellowship Until December 31, 2010, Dr. McCracken was McCracken the principal the Dr. of NICHD investigator Pediatric Pharmacology 2010, 31, December Until and UT All Southwestern. bothparticipate at Children’s located Research fellows Network with in research projects faculty. the 130 Infectious Disease Theresa Barton, M.D. Jeffrey S. M.D.,Kahn, Ph.D. Major Administrative Responsibilities orLeadership H.McCracken Jr.,George M.D. M.D, Gill, Michelle Ph.D. Garcia,Carla M.D. Theresa Barton, M.D. Jeffrey S. M.D.,Kahn, Ph.D. provinceLimpopo of Africa. South for Waterberg people the in services education support involved and providing region of in the fellows directly are for HIV/AIDS program adults, and services children medical to providing addition In forexperience participants. TheUT Southwestern Fellowship Clinical in South Africa provides an educational and enlightening medical Co-chair, ARV Therapy Working Group, LEGACY CDC Project Interim Director, UTSouthwestern ClinicalFellowship inSouth Africa Clinical Director, Ryan White Title IVPrograms (DFAN and Youth Angle) Member, of Board Directors, HIVMedical Association Co-director, Fellowship Training Program, Pediatric Infectious Disease Co-Director, Antimicrobial Stewardship Committee, Children’s Medical Center, Dallas Director, Fellowship Training Program, Pediatric Infectious Disease Director, Division of Pediatric Infectious Disease Seminar, Richardson, April TX, 2010 “Use of Antibiotics inInfants and Children,” 42nd Annual Kenneth C.Haltalin Pediatrics for Practitioner the NIAID Inner City Asthma Consortium Steering Committee Meeting, Chicago, IL,September 2010 “Allergen Interference with Viral-induced Plasmacytoid De Academy Asthma of &Immunology Allergy Meeting, New Orleans, Month LA, 2010(Poster Presentation) “IgE Crosslinking on Human Ce Plasmacytoid Dendritic PediatricDallas, Academic Societies’ Annual Meeting, Vancouver, Canada, May 2010(Poster presentation) Associated of“Rhinovirus, Spectrum Disease with Diag the Vancouver, 2010(Poster October Canada, presentation) in Children Hospitalized with Bronchiolitis,” Annual 48th “Respiratory Virus Syncytial Variability (RSV) Genetic an A Mejias, CYang, CGarcia, SKhokhar, SChavez-Bueno, CSomers, JTorres, HJafri, KWang, and ORamilo. 2010(PosterOctober presentation) Atopicthe Background,” Annual 48th Meeting of Vancouver, America, of Society Infectious the Disease Canada, Tracttory Infections (LRTI)Caused asThose asSevere Respiratoryby Syncytial (RSV) Virus Independently of C Garcia, ASoriano, SKhokhar, PRevell, ORamilo, and AMejias. (RV) “Rhinoviruses Cause Lower Respira- May 2010(Poster presentation) dren at Children’s Medical Center of Dallas,” Pediat M Trost, CGarcia, and WLee, MGill. “Spectrum of Dise Pediatric Academic Annual Meeting, Societies Vancouver, Canada, May 2010(Poster presentation) Extracorporeal Membrane Oxygenation (ECMO) and Continuous Venous-Venous Hemofiltration (CVVHD),” C Garcia, CTucker, PJSanchez, RLeff, and MIArdura. “P “Pediatric HIVInfection,” UTArlington of School Nursing, September 2010 (WHICC), Houston, Month TX 2010 “Maternal-to-Child HIVTransmission,” Panel Discussio “Health Literacy,” Women &HIVInternational ClinicalConference (WHICC), Houston, Month TX, 2010 vention &Scientific Assembly, Orlando, FL, Month 2010 Perinatal Transmission inMinority Women,” Satellite Symposium, National Medical Association Annual Con- “Recent Guidelines and Evidence for Prenatal Care Re ter, Month 2010 “Growing Up Positive: The Evolution of Pediatric HIV/AIDS,” Pediatric Grand Rounds, Children’s Cen- Medical “Swine Flu: One Year and Still Counting Grand Rounds, Children’s Medical Center, February, 2010 Long Deadly and“The History of Influenza the Emergenceand theof Novel 2009H1N1Swine Flu,”Pediatric “Influenza,”Dallas (DSD),IndependentSchool District SeptemberScience TX, 2010 NASA Symposium,Dallas, Richardson, Texas, April 2010 “Influenza: OldChallenges, Challenges,”New 42nd Annual K in Epidemiology of State Infectious Diseases, College, Pennsylvania, March, 2010 “Emerging Human Parvoviruses,” Center Penn for Dynamics, Infectious State Disease University, series Seminar ,” Op-Ed, Dallas ric Academic Annualric Meeting, Societies Vancouver, Canada, commendations inHIV-Infected Mothers, Reducing HIV n, Women &HIVInternational ClinicalConference Morning News, April 2010 lls Interferes with CD4Alloproliferation,” American ase Associatedase with inChil- Diagnosisof Rhinoviruses d Viral Not Do Loads Correlate Severity with Disease harmacokinetics (PK)of Peramivir inaChildDuring Meeting of America, of Society Infectious the Disease ndritic Cell Function;ndritic Cell Mechanisms of Disease,” NIH/ nosis of at Rhinovirus Children’s Medical Center of enneth C.Haltalinenneth Pediatrics for Practitioner, the Infectious Disease 131 re Fall Exacerbations) Clinical Trial Protocol Team, Team, Protocol Clinical Trial Exacerbations) Fall re She participates in HIV community programs participates She only dedicated pediatric hiv pediatric dedicated only
DSA and PIDS Fellows Travel Grant Award, 46th Annual Meeting of the Infectious Disease the Infectious Society of America. of Meeting 46th Annual Award, Grant Travel PIDS Fellows DSA and Vancouver, Canada 2007-2010 Clinical Sciences, of UT Southwestern, Department Scholar, Clinical Research Co-coordinator, Pediatric Intern Retreat, Children’s Retreat, Intern Pediatric Co-coordinator, 2007-2010 Clinical Sciences, of UT Southwestern, Department Scholar, Clinical Research Medical Director, Infection Control, Children’s Control, Infection Director, Medical Children’s Committee, Control Infection Chair, Reporting Public Infection Care-Associated Health for Panel Advisory State Texas Member, Council Hospital Worth Dallas Fort Committee, Safety Patient Member, Society Pediatric Texas Diseases Immunizations, Infectious and of Committee Member, patients CMC of contacts to vaccine influenza provide to program of oversight and Initiation Chair, Committee of Infectious Diseases and Immunizations, Texas Pediatric Society Pediatric Texas Diseases Immunizations, Infectious and of Committee Chair, Diseases Infectious in Children Board, Advisory Editorial Member, Drug and Food (VRBPAC), Committee Advisory Products Biological Related and Vaccines Member, (FDA) Administration Review Panel (CHHD-A) Subcommittee Pediatrics NICHD Member, Research Society Pediatric for Committee, Nominating Member, Director, Pediatric Residency Training Program Residency Training Pediatric Director, Conference Morbidity and Residency Mortality Course Director, Center Medical Children’s at Education Medical Director, Committee Directors Program Training Center Medical Children’s Chair, DiseaseJournal Infectious Pediatric The Chief Editor, NIH/NIAID Inner City Asthma Consortium Consortium Asthma City Inner NIH/NIAID 2010 Committee, Presentations and Publications Consortium Asthma City Inner NIH/NIAID Member, Committee, Development Studies Mechanistic PROSE Consortium Asthma City Inner NIH/NIAID Member, 2010 DiseaseJournal Infectious Pediatric The Chief Editor, Disease Infectious Foundation Pediatric National Treasurer, and President Reviewer for SPR research abstract submissions in the area of infectious diseases for the 2010 Pediatric Society diseases the Pediatric 2010 infectious for of in the area submissions abstract research SPR Reviewer for Meetings for Seve Therapy Omalizumab (Preventative PROSE Member, Started and lead the Infectious Disease Service in-patient and out-patient consultations at Children’s Medical Medical Children’s at consultations Disease out-patient lead Service the Infectious and and Started in-patient Legacy at Center clinic in North Texas. in North clinic once a year. once and national HIV organizations, as well as does medical volunteer work in Haiti at least least in Haiti at work medical as as HIV well does and volunteer national organizations, Dr. Theresa Barton Theresa runs the Dr. Asuncion Maria Mejias, M.D. Mejias, Maria Asuncion Monica Ardura, D.O. Ardura, Monica M.D. Carla Garcia, Awards and HonorsAwards M.D. D Siegel, Jane Pablo Sanchez, M.D. Pablo M.D. Nelson, D. John M.D. McKinney, Jeffrey George H. McCracken, Jr., M.D. George Jr., H. McCracken, Michelle Gill, M.D, Ph.D. Michelle Gill, M.D, Carla Garcia, M.D. Carla Garcia, 132 Infectious Disease Neonatal-Perinatal Medicine 133 Director, Neonatal-Perinatal Medicine Neonatal-Perinatal Director, Rashmin Savani, M.B.,Ch.B. Rashmin Savani, in vitro and in vivo approaches to examine macrophage and and macrophage examine to approaches in vivo and in vitro ics and gynecology ics and 1984. He 1982 to from Neonatal-Perinatal Medicine Neonatal-Perinatal Faculty Neonatal-Perinatal of is Director Professor, M.B.,Ch.B., Rashmin Savani, in Chair Buchanan the William holds and UT Southwestern at Medicine Biology Vascular Pulmonary and of Director is also the Associate He Pediatrics. the from his medical degree obtained Savani Dr. Pediatrics. of in the Department internal in internships and undertook in 1982 England, Sheffield, of University obstetr and surgery, general medicine, N.C., from Durham, Center, Medical University Duke at was a pediatric resident in Center Medical Children’s Cincinnati at held fellowships 1987 and 1984 to 1991. 1989 to in Pulmonary Biology 1989 and from 1987 to from Neonatology in the Section Neonatology of Pediatrics of Professor Assistant was an Savani Dr. from Canada, Winnipeg, Hospital, Children’s and Manitoba of the University at in he undertook training this 1996. During time, further1991 to postgraduate 1991 Cell Biology of from Institute the Manitoba Biology at Molecular Cell and to he was recruited until the Institute at lab independent 1994; then had an to in 1996. Philadelphia of Hospital Children’s and Pennsylvania of the University in 2002, a position Tenure with Professor Associate of rank to rosethe he There Savani’s Dr. UT Southwestern. to 2006 when he was recruited he held until and surfactant dysplasia, expertise bronchopulmonary clinical of is in the areas including development, injury and focus has been the newborn, lung of on his research and pulmonary hypertension in a variety receptors its and acid (HA) hyaluronic of role the is studying laboratory His angiogenesis. and inflammation and transgenic include in the laboratory Projects injury. lung to in particular the response tissue injury, models of of as as well pathways, signaling intracellular mice, knockout injury. lung to response and the alveolarization angiogenesis, and inflammation to cell biology as theyendothelial relate In 2010, the division has grown withIn 2010, Davis, the Drs. Arlene addition of Julie Mirpuri, and Muraleedharan Emily Osier, sorry Drs. Donald McCurnin lose were to andSivarajan Rodica Catrinel the to We faculty. Marinescu to moved who familyother cities for reasons. Neonatal-Perinatal Medicine includes basic science projects and neonatal translational and clinicalas large collaborative clinical the the by Neonatal Research Maternal-Fetal Network, conducted projects, Medicine projects as well cytomegalovirus and of the Network, role infection (CMV) in hearing disability, and all loss developmental sponsored the NIH.by The wealth The of patients under the careof the division a of high affords academic level and scholarly activity. Medical student, resident and fellow education programs provide teaching of clinicalor clinical skills, research. as well as experience in basic and/ Working closely with closely Maternal-FetalWorking Medicine and other pediatric subspecialties, the division coordinates the Fetal Program Alliance multidisciplinary that provides andEvaluation Treatment (FETAL) antenatal advanced consultation, imaging, fetal intervention anddelivery Team planning referrals and Resuscitation for The beyond. from North Texas in Labor and Delivery an is internationally acclaimed program providing state-of-the-art assistance newborn to infants as they transition extra-uterine to life. Clinic infants In the addition, Birth Low follows severely born Weight growth up andprematurely those neonatal had chronic ensure that to appropriate disorders and have development three. age to The division coordinates integrated neonatal care across the UT Southwestern, Parkland and Children’s campuses, thanincluding more 15,000 deliveries annually Parkland at Health which 1,300 of are System, & Hospital admitted to takeof to infants geared care with complex is Children’s at Parkland.referral 36-bed at NICU the 90-bed The NICU medical and surgical and those with problems, special metabolic, cardiac, surgical or are transferred who conditions care. a higherfrom of other hospitals level for The Division of Neonatal-Perinatalof DivisionThe Medicine maintains a highprofile within the Department Pediatrics, of well as Parklandas at providing the clinical highest of and level Children’s, The is caredivision each site. at responsible also high-qualityfor academic programs substantial that enjoy extramural funding as well record, and as publication inexcellence teaching the at divisional, departmental and university Neonatal-Perinatal levels. faculty be to continue invited nationally and internationally and serve committees present on to advance to neonatal care. 134 Neonatal-Perinatal Medicine Education: expertise: Clinical/research Associate Professor Mahmood Alasmi, M.D., M.S. 2010 Pediatrics, 2004-2007;Baylor College of Medicine, Fellow, Neonatal-Perinatal Medicine, 2007- Post-doctoral training: PA, M.D., 2004 Education: expertise: Clinical/research Assistant Professor Arlene Davis, M.D. Resident, Pediatrics, 2001-2003 Southwestern, Fellow, Neonatal-Perinatal Medicine, 1998-2001;UTSouthwestern/Children’s, Post-doctoral training: 2008-2011 Medical M.D., School, 1995;UTSouthwestern, ClinicalResearch Scholar, ClinicalSciences, Education: neurologicbedside monitoring expertise: Clinical/research Assistant Professor Lina Chalak,M.D. Neonatology, 1983-1985 Fellow, Neonatology, Einstein of College 1982-1983;Albert Medicine, New York, NY, Fellow, Fellow, Neonatology, 1982;Cliniques Universitaires, Hôpital Erasme, Bruxelles, Belgium, 1981; University of Toronto, Canada, Fellow, Neonatology, 1981-1982;Institut Edith Cavell, Pediatrics, 1976-1979;Institut Edith Cavell, Post-doctoral training: in Pediatrics, 1981 1972; M.D., 1976;Université Libre deBruxelles, Bruxelles, Special Belgium, Bachelors Degree Education: Neonatal Research Network and other multicenter clinical trials expertise: Clinical/research Professor Luc P. Brion,M.D. Bioinformatics, 2010. Southwestern, Fellow, Neonatal-Perinatal Medicine, 1991-1994;Master of Medical Science, Post-doctoral training: Education: bioinformatics expertise: Clinical/research Assistant Professor Timothy Brannon, M.D. Post-doctoral training: Center,Science Fort Worth, D.O., 2004 Education: expertise: Clinical/research Assistant Professor Sue Bacsik,D.O. Candidate, 1995-1997 Center, OH, Pediatric ClinicalResearch Fellow and Biostatistics and Epidemiology Master Center, OH, Fellow, Neonatal-Perinatal Medicine, 1993-1996;University of Cincinnati Medical Pediatrics, 1990-1993;University of Cincinnati Medical Center/Children’s Hospital Medical Post-doctoral training: Yale University, New Haven, CT, B.S., 1999;Jefferson College, Medical Philadelphia, American University Lebanon, of B.S., Beirut, 1991;American University of Beirut Université Libre deBruxelles, Bruxelles, Bachelor Belgium, of Medical Sciences, Baylor University, Waco, B.S., 1984;UTSouthwestern, TX, M.D., 1988 Texas Tech University, Lubbock, B.S., 1998;University of North Texas Health AinShams University, of School Medicine, Cairo, M.B., Egypt, B.Ch., 1984 Emory University Emory College of Medicine, Atlanta, GA,Resident, Hospital Universitaire Saint Pierre, Bruxelles, Resident, Belgium, UTSouthwestern/Children’s, Resident, Pediatrics, 1988-1991;UT UTSouthwestern/Children’s, Resident, Pediatrics, 2004-2007 Hahnemann University Hospital, Philadelphia, PA, Resident, American University Resident, of Beirut, Pediatrics, 1995-1998;UT Neonatal-perinatal medicine, neonatal nutrition, health global Hypoxic-ischemic encephalopathy, brain newborn, inthe injury Neonatal care, and newborn electronic medicalrecords, Neonatal care, and newborn nutrition Fellowship medicine, training, renal evidence-based disorders, Neonatal care, and newborn breastfeeding Bruxelles, Resident, Belgium, Pediatrics, 1979- Neonatal-Perinatal Medicine 135 Mechanical ventilation, neonatal nutrition, neonatal resuscitation, resuscitation, neonatal nutrition, neonatal ventilation, Mechanical Neonatal & newborn care, community advocacy, fellow education education fellow advocacy, community & newborn care, Neonatal Developmental follow-up of complex high-risk infants and very and high-risk infants complex of follow-up Developmental preterm late infection, neonatal hyperbilirubinemia, Neonatal Ethics and palliative care, neonatal outreach, resident education resident outreach, neonatal care, palliative and Ethics Bilirubin metabolism and neonatal hyperbilirubinemia, blood hyperbilirubinemia, neonatal metabolism and Bilirubin Seth G.S. Medical College and King Edward Memorial Hospital, Hospital, Memorial Edward King and College Seth G.S. Medical University of Michigan Medical Center, Mott Children’s Hospital, Hospital, Children’s Mott Center, Medical Michigan of University UT Health Science Center at San Antonio, Resident, Pediatrics, 1989- Pediatrics, Resident, Antonio, San Science at Center UT Health St. Joseph Hospital, Denver, CO, Rotating Intern, 1974-1975; UT Intern, Rotating CO, Denver, Hospital, Joseph St. 1972- Pediatrics, GA, Resident, Atlanta, Hospitals, Emory Affiliated UT Southwestern/Children’s, Resident, Pediatrics, 2000-2003; UT 2000-2003; Pediatrics, Resident, UT Southwestern/Children’s, Bangalore Medical College, Bangalore University, India, M.B.B.S., 1994 M.B.B.S., India, University, Bangalore College, Medical Bangalore UT Austin, B.B.A., 1985; Ohio State University College of Medicine, Columbus, Columbus, Medicine, College of University Ohio State 1985; B.B.A., UT Austin, Pomona College, Claremont, CA, B.A., 1970; University of Colorado School of School Colorado of of University 1970; CA, B.A., Claremont, College, Pomona of College 1968; Baylor B.A., Southern Los California, Angeles, of University Emory University, Atlanta, GA, B.S.N., 1992; UT Southwestern, M.D., 2000 M.D., 1992; UT Southwestern, GA, B.S.N., Atlanta, Emory University, Dartmouth College, Hanover, NH, B.A., 1970; Tufts University School of Medicine, of School University 1970; Tufts NH, B.A., Hanover, College, Dartmouth Assistant Professor Assistant Clinical/research expertise: Education: 1989 M.D., training: Post-doctoral 1992-1995 Medicine, Neonatal-Perinatal Fellow, RI, Providence, University, 1992; Brown Sunjun Kang, M.D. Sunjun Kang, electronic medical records electronic Education: training: Post-doctoral Mambarath Jaleel, M.D. Jaleel, Mambarath Professor Assistant Clinical/research expertise: of 1995-1998; Canberra Clinical School, University Pediatrics, Resident, India, Mumbai, Brown Hospital, Infants and 1998-2000; Women Neonatology, Fellow, Australia, Sydney, 2001-2004; Children’s Medicine, Neonatal-Perinatal RI, Fellow, School, Providence, Medical 2005-2006 Pediatrics, Resident, NJ, Monmouth, Center, Medical Monmouth at Hospital Professor Clinical/research expertise: Gregory Jackson, M.D., M.B.A. Gregory Jackson, M.D., low birth weight, community advocacy community birth weight, low Education: 1974 M.D., Denver, Medicine, training: Post-doctoral 1975-1978 Pediatrics, Resident, Southwestern/Children’s, infants Education: 1992 M.B.A., Denton, Texas, North of 1972, University TX, M.D., Houston, Medicine, training: Post-doctoral 1973-1975 Pediatrics, Houston, TX, Resident, Hospitals, Affiliated 1973; Baylor Professor Clinical/research expertise: Roy J. Heyne, M.D. Heyne, J. Roy Becky Ennis, M.D. BeckyEnnis, Professor Assistant Clinical/research expertise: Education: training: Post-doctoral 2003-2006 Medicine, Neonatal-Perinatal Fellow, Southwestern, William D. Engle, M.D. Engle, D. William Professor Clinical/research expertise: pressure, late preterm infants preterm late pressure, Education: 1974 Boston, M.D., MA, training: Post-doctoral Medicine, School of Pennsylvania of University 1974-1978; Pediatrics, Resident, Ann Arbor, 1978-1980 Neonatology, Fellow, Philadelphia, 136 Neonatal-Perinatal Medicine Neonatology, 2005-2006;UTSouthwestern, Fellow, Neonatology, 2006-2008 Philadelphia, PA, Resident, Pediatrics, 2003-2005;Childr Pediatrics, 2002-2003;Drexel Collegeof Medicine/St. Christopher’s Hospital for Children, Human Einstein Medical 2001-2002;Albert Genetics, Center, Philadelphia, PA, Resident, Post-doctoral training: Education: Clinical/research expertise: Clinical/research Assistant Professor Rodica Catrinel Marinescu, M.D. Post-doctoral training: Education: expertise: Clinical/research Assistant Professor Susan Raff, M.D. Post-doctoral training: ofSchool Medicine, Atlanta, GA, M.D., 2007 Education: expertise: Clinical/research Assistant Professor Emily Osier, M.D. University,2007; Emory Atlanta, GA,Fellow, Neonatal-Perinatal Medicine, 2007-2010 and Surgery, Children’s 2000-2001;Goryeb Hospital, Morristown, NJ, Resident, Pediatrics, 2004- Post-doctoral training: of Hong Kong, M.B.B.S., 2000 Education: interactions expertise: Clinical/research Instructor Julie Mirpuri-Hathiramani, M.D. Fellow, Neonatology, 1990-1993 Fellow, Pediatric Cardiology, 1983-1985; Wilford Hall, USAFMedical Center, San Antonio, TX, Pediatrics, 1980-1983, Baylor College of Medicine/Texas Children’s Hospital, Houston, TX, Post-doctoral training: Education: hypertension, severe BPD expertise: Clinical/research Medical Director, NICU, Children’s Medical Center of Dallas Professor, Pediatrics and Cardiology Donald McCurnin, M.D. Post-doctoral training: at Galveston, M.D., 2006 Education: education expertise: Clinical/research Assistant Professor Laura McClendon,M.D. St. Mary’s Canossian College, Hong Kong, Advanced 1995;University Sciences, Level Universitatea Medicina-Farmacia, De Bucharest, Romania, M.D., 1994. Indiana University, Bloomington, University B.A., distinction,2002;Emory high UTAustin, B.A., 1972;UTHealth Center, Science San Antonio, M.D., 1980 Texas A&MUniversity, College Station, B.A., laude, cum 1999;UTMedical Branch UT Austin, B.A., 2000;UTMedical Branch at Galveston, M.D., 2004 Hospital Authority of Hong Kong, Floating Resident, Pediatrics, Medicine UTSouthwestern/Children’s, Resident, Pediatrics, 2004-2007 UTSouthwestern/Children’s, Resident, Pediatrics, 2007-2010 Wilford Hall, USAFMedical Center, San Antonio, Resident, TX, UTSouthwestern/Children’s, Resident, Pediatrics, 2006-2009 Thomas Jefferson University, Philadelphia, PA,Research Fellow, Necrotizing enterocolitis, gut immunology, host-gut microbiota Pulmonary hypertension, Pulmonary neonatal cardiac ECMO disease, Neonatal care, and newborn electronic medicalrecords ECMO, transport, pulmonary congenital diseases, heart Neonatal care, and newborn resident and medicalstudent Neonatal care, and newborn resident education en’s Hospital, Philadelphia, PA, Fellow, Neonatal-Perinatal Medicine 137 erbilirubinemia, newborn nutrition, newbornerbilirubinemia, nutrition, ition, neonatal origins of metabolic syndrome, metabolic syndrome, of origins neonatal ition, Endothelial cell biology, nitric oxide, caveolae-lipid rafts, estrogen, estrogen, rafts, caveolae-lipid oxide, nitric cell biology, Endothelial Neonatal and newborn care, clinical bioinformatics, electronic electronic bioinformatics, clinical newborn and care, Neonatal hyp neonatal Breastfeeding, Neonatal and congenital infections, Neonatal Research Network Network Research Neonatal infections, congenital and Neonatal Uteroplacental blood flow, development of the rennin-angiotensin rennin-angiotensin of the development blood flow, Uteroplacental Neonatal neurology, hypoxic-ischemic encephalopathy, amplitude- encephalopathy, hypoxic-ischemic neurology, Neonatal University of Alabama at Birmingham, Fellow, Neonatology, Neonatology, Fellow, Birmingham, at Alabama of University Children’s Medical Center of Cincinnati, University of Cincinnati, Cincinnati, of University Cincinnati, of Center Medical Children’s Baylor College of Medicine, Houston, TX, Resident, Pediatrics, 1995- TX, Pediatrics, Resident, Houston, Medicine, College of Baylor 1982-1985 Pediatrics, Resident, UT Southwestern/Children’s, Children’s Hospital of Pittsburgh, PA, Resident, Pediatrics, 1981-1984; Pediatrics, Resident, PA, Pittsburgh, of Hospital Children’s Yale-New Haven Medical Center, CT, Resident, Pediatrics, 1966-1967; Pediatrics, Resident, CT, Center, Medical Haven Yale-New Istanbul University, Istanbul Faculty of Medicine, Turkey, M.D., 1993 M.D., Turkey, Medicine, of Faculty Istanbul University, Istanbul Dartmouth College, Hanover, NH, B.A., 1977; University of Cincinnati, OH, M.D., M.D., OH, Cincinnati, of 1977; University NH, B.A., Hanover, College, Dartmouth St. Joseph’s College, Philadelphia, PA, B.S., 1974; Columbia University, New York, York, New University, 1974; Columbia B.S., PA, Philadelphia, College, Joseph’s St. Medical Jersey 1978; New B.S., NJ, Piscataway, Engineering, of College Rutgers Seton Hall University, South Orange, NJ, B.S., 1977; University of Pittsburgh School Pittsburgh of 1977; University B.S., NJ, Orange, South University, Hall Seton Emory University, Atlanta, GA, M.D., 1966 GA, M.D., Atlanta, Emory University, Assistant Professor Assistant Clinical/research expertise: Julide Sisman, M.D. EED integrated Education: training: Post-doctoral Fellow, NY, Medical Center, Medicine/Montefiore 2000-2001; Albert of College Einstein Chief 2003-2005; Pediatrics, Resident, NY, Center, Medical 2001-2003; Albany Neonatology, 2005-2006 Pediatrics, Resident, Philip W. Shaul, M.D. Shaul, W. Philip Professor Biology Vascular Pulmonary and of Division Director, Research Care Critical in Pediatric Professorship Foundation Lowe Clinical/research expertise: HDL and CRP signaling CRP signaling and HDL Education: 1981 training: Post-doctoral Brown Rhode of Island, Hospital Infants and Women Pediatrics,1981-1984, Resident, OH, 1984-1986 Medicine, Neonatal-Perinatal Fellow, Providence, University, Dorothy Sendelbach, M.D. Dorothy Professor Associate Clinical/research expertise: medical records Education: 1995 GA, M.D., Atlanta, Medicine, School of 1977; Emory M.B.A., University NY, training: Post-doctoral MA, Fellow, Hole, Woods Laboratory, Biological Marine Medicine, Library of 1998; National 2005 Informatics, Medical infants preterm late Education: 1982 M.D., School, Newark, training: Post-doctoral Joseph Schneider, M.D., M.B.A. M.D., Joseph Schneider, Professor Clinical Assistant Clinical/research expertise: Pablo J. Sánchez, J. M.D. Pablo Professor Clinical/research expertise: trials multicenter other and Education: 1981 M.D., PA, Medicine, of training: Post-doctoral UT 1984-1986; Neonatology, Fellow, NY, York, New Center, Medical Columbia-Presbyterian Disease, Infectious 1986-1988 Pediatric Fellow, Southwestern, Charles R. Rosenfeld, M.D. R. Rosenfeld, Charles Gynecology Obstetrics and and Management, Anesthesiology Pain and Pediatrics, Professor, in Pediatrics Professorship MacGregor L. George Clinical/research expertise: system, fetal growth restriction, neonatal nutr neonatal restriction, growth fetal system, PDA and blood pressure regulation blood pressure and PDA Education: training: Post-doctoral NY, York, New Medicine, Albert College of and Einstein Center Hospital Municipal Bronx 1970-1971; University Pulmonary Medicine, Pediatric Fellow, 1967-1970; Pediatrics, Resident, 1971-1973 Medicine, Neonatal-Perinatal Fellow, Denver, Center, Medical Colorado of Neonatal-Perinatal Medicine 138 4th Year JuneCompleted 2010 Post-doctoral Fellows induced Fc gamma receptor Isignaling inCRP hypertension Interests: Research Nathan C.Sundgren, M.D., Ph.D. development Ephrin B2and Eph B4receptors inlung Interests: Research Women’s Hospital, Albuquerque, NM Sheridan’s Healthcare Corp., Lovelace Current Position: Katherine M.D. Bennett, Post-doctoral training: Education: infection Southwestern, Fellow, Neonatal-Perinatal Medicine, 1997-2000 Post-doctoral training: Education: monitoring 2005; Fellow, Neonatal-Perinatal Medicine, 2005-2008 Post-doctoral training: D.O., 2002;University of Arkansas for Medical Little M.P.H., Rock, Sciences, 2008 Education: resident education Resident, Pediatrics, 2001-2004 Post-doctoral training: M.R.C.P.I., 1995 Medical College, Kanpur, India, D.C. H.,1990;Roya Education: expertise: Clinical/research Assistant Professor Muraleedharan Sivarajan, M.D. Clinical/research expertise: Clinical/research Associate Professor Myra H. Wyckoff, M.D. expertise: Clinical/research Assistant Professor Audra D.O., Stewart, M.P.H. expertise: Clinical/research Associate Professor Elizabeth Stehel, M.D. Trinity University, San Antonio, B.S., 1990;UTSouthwestern, TX, M.D., 1994 Trivandrum Medical College, University of Kerela, India, M.B.B.S., 1989;GSVM University of California-San Diego, B.S., 1993;UTSouthwestern, M.D., 1997 University of Oklahoma, Norman, B.S., 1996;Oklahoma State University, Tulsa, UTSouthwestern/Children’s, Resident, Pediatrics, 1997-2000 UTSouthwestern/Children’s, Resident, Pediatrics, 1994-1997;UT Arkansas Children’s Hospital, Little Resident, Rock, Pediatrics, 2002- Lincoln Medical and Mental Health Center, Bronx, NY, Intern and Newborn resuscitation, resident education, non-invasive Neonatal care, and newborn congenital hearing loss,advocacy, Breastfeeding, resident and medic Neonatal care, and newborn resident education l College ofl College Physicians of Ireland, Dublin, o yohri rvnini premature for hypothermia prevention in newborns Effectiveness coveringof head plastic Interests: Research Pediatrix, San Antonio, TX Current Position: TengLilian St.John, M.D. al student education, neonatal Neonatal-Perinatal Medicine 139 Jacklyn LeVan, M.D. LeVan, Jacklyn Research Interests: clinical on clinical trials of Influence patients in non-enrolled practice Michel Mikhael, M.D. Research Interests: HPI axis in infants of Studies surgery cardiac undergoing M.D. Stumpf, Katherine Research Interests: in the pre- tract infection Urinary observational an study; term population: in very low immunization rotavirus infant birth weight Vishal Kapadia, M.D. Kapadia, Vishal Research Interests: infants in preterm stress Oxidative 100% 21% or either with resuscitated oxygen M.D. Sparks, John ResearchInterests: breaths to compression chest Optimum a piglet using resuscitation in neonatal model Research Interests: development in lung B2 Ephrin M.D. DuPont, Tara ResearchInterests: encephalopathy hypoxic body and cooling Total ischemic Maria Afanador, M.D. Afanador, Maria Research Interests: prevent to therapies Mechanism-based syndrome the antiphospholipid Ja’near Anderson, M.D. Anderson, Ja’near Research Interests: ephedrine the use of being and well Fetal delivery hypotension maternal of in the treatment during M.B.B.S. Osunbunmi, Olutoye Jenita Jeyarai, M.D. Jeyarai, Jenita Research Interests: alveolarization and RHAMM Hyperoxia, Joshua Frankfurt, M.D. Joshua Research Interests: blood pressure aberrant of Biomarkers in VLBWs regulation Natalie Frost, M.D. Frost, Natalie Research Interests: neonatal ß and receptor Estrogen alveolarization Year 1st 2nd Year 3rd Year 3rd 140 Neonatal-Perinatal Medicine division has been a participating member of this network its since member of this beenaparticipating has division Development Human and Health of (NICHD). Child Institute The consisting of 18 institutions in North America, sponsored by National projectscollaborative conducted Network Research Neonatal by the the projects conducted research include through studies Clinical resuscitation. neonatal and deficiency, surfactant genetic dysplasia, of models bronchopulmonary Translational projects include animal proliferation. and migration cell of regulation matrix and extracellular models, animal in injury and lung inflammation pathogenesis of blood pressure beforebirth, after and regulating uteroplacental blood flow in pregnancy, regulating mechanisms development pulmonary and mechanisms disease, and cardiovascular to respect biology with cell endothelial vasodilators, other oxide and nitric of regulation molecular and cellular on I Assistant Research focused Sosa, David Sergio are projects projects. Basic science clinical and translational basic, including activity, of research in a division isengagedbroad The spectrum Vasil, Diana RN Data Specialist Sontoyo, Erica Clinical Sontoyo, Rebeca Technical Lab Assistant Jessica Sontoyo, Technical Lab Assistant I Rosado, Assistant Research Oscar Research Activities Timothy Roy, Torres, II Assistant Research Lizette RN RN Guzman, Alicia RN Miller, Nancy Technician Research I B.S., Mija, Dan Technician Jason Research Mitchell, I Technician Research Christopher Longoria, I Xiao-Tie Ph.D., Liu, Sr. Associate Research Jie Liao, Ph.D., Sr. Associate Research Technician Research II Garcia, Damien I Assistant Research DeSpain, Kevin Cheong,Naeun Ph.D., Sr. Scientist Research Research Staff RN Christie, Lucy Lijun Chen, PhD, RN RN Burchfield, Jeannette RN Boatman, Cathy Research Nurses StaffClinical/Research Sundgren,Nathan C. M.D., Ph.D. TengLilian St.John, M.D. M.D. Sparks, Eric John M.D. Kapadia, Vishal Natalie Frost, M.D. Katherine Bennett, M.D. 2009-2010. during funding extra-mural and intra- obtaining in fellows have current six beensuccessful The success ofthe research endeavors ofthe Neonatal-Perinatal Medicine fellowship are highlighted bythe factthat Physician Scientist Training Program, UT Southwestern, 2008-2011 UT Program, Physician Training Scientist Premature Newborns,” in $10,000Hypothermia (2008-2010) Young and Grant Research Investigatorthe Award, NRP Hats Prevention of for Plastic-Lined “Effectiveness of YoungNRP 2010 Investigator Grant, neonatal CPR”, during 2010 ventilation and compressions cardiac “Simultaneous Grant, Foundation Hospital Children’s of preterm resuscitation infants”, 2010 neonatal during oxygen of “Use Grant, Initiative Science Translational & Texas Clinical North $10,000 (2009-2010) Receptor Estrogen “Estrogen Modulation and of BPD,” Program, Grant Medicine Newborn Advancing Ikaria: in Morphogenesis,”Lung Role2009, “The ReverseB2 $5,000 Signaling (2009-2010) Ephrin of 2008- Pediatrics, on Perinatal Section Academy of Pediatrics, Award American Research the from Perinatal Klaus Neonatal-Perinatal Medicine 141 across the UT Southwestern, Children’s and Parkland campuses. Children’s the UTacross Southwestern, Integrated Fetal and Neonatal Care and Neonatal Fetal Integrated Division facultyDivision coordinate Children’s Medical Center Children’s seen have we Children’s, at D Tower Afteropening 36-bedthe in NICU growthcontinued in admissions this to unit.quality The of program the was recognized Optum by awarding Health Healthcare), (part United of in NICUs the unit only Excellence” 61 of of designation, the one “Center the given this US designation, and the in only Dallas. one This unit has the bolstered strengths the of campus program in Neonatal-Perinatal Medicine, and has seen referrals from within the Dallas/Fort Worth The and unit beyond. cares andfor throughout North Metroplex Texas infants medical with and complex surgical and those with problems, special metabolic, cardiac surgical or conditions transferred care. a higher from other of hospitalsmortality level for The for these extremely sick infantsless is than 6 Continued growthpercent. is anticipated, and neonatal neonatologists, nursing and APN recruitment An is ongoing. electronic databasewith has its already The division continues involvement been established the Children’s. at NICU for Hospitals Neonatal Database. the Children’s Neonatal-Perinatal Medicine faculty participated in the care of more than 1,300 neonates admitted to theas an admitted NICU, additional as neonates the 14,000 Parkland. to at NBN well with collaboration close Continued the faculty and infellows the Maternal-Fetal Medicine Division in the Department Obstetrics of and Gynecology ensures optimal delivery this pregnancies. Despite high-risk delivery at-risk plans for service, neonatal mortality adjusted remains less than four fellows, benchmarkper 1,000 to births live institutions Faculty, extremely nationwide. compare favorably and outcomes advanced practice nurses (APN) and residents provide integrated neonatal care at three levels of acuity in a 90-bedThe Resuscitation Program, NICU.provides Myra a Wyckoff, directed by Dr. coordinated multidisciplinary team attendance high-risk at deliveries. Comprehensive electronic databases have been actively in use for more than fifteen years the over 25 years and NICU for for inthe Resuscitation Program. Clinical Activities Parkland Memorial Hospital Research funding exceeded $1.75 million themore fiscal than Research for are There funding eightyear. NIH-supported grants $1.75 within exceeded than funded more the 30 years. which has for been continuously division, Other funding one of sources an include chair UT by awarded as Southwestern, and wellendowed two as smaller professorships and pharmaceutical foundation grants. research company of the division’s activities including resuscitation, NBN, both NICUs as well as the Follow Up Clinic. In addition, addition, In Clinic. Up Follow the as well as NICUs both NBN, resuscitation, including activities Clinical databases in the projects that division are are maintained facilitated the by comprehensive in each area division’s the of Hospitals’ andthe the Network Oxford division Children’s and partner its the hospitals of are Vermont members Neonatal Database collaboratives. General the neonatal include natural projects history and ductus diagnosis arteriosus, patent of optimization of resuscitation and stabilization the of newborn in the delivery including room temperature stabilization, oxygen use thehypocalcaemiagentamicinand effect of cardiac on compressions, of glucocorticoids in newborn,and role the and treatment to in thevasopressors in birth pressure regulation very approaches blood low neonates, of weight infection of in theprevention newborn, thebirthregulationpressure effectsvery of 3 to blood low 1 at on weight infants, preterm late years, of complications and studies hyperbilirubinemia the of of recognition and prevention in neonates. inception in 1986 and Other successfully ininception national 1986 collaborative the studies next for in cycle include 2010. competed CMV of the infection role in hearingdisability. this and loss strategies long-term prevent to 142 Neonatal-Perinatal Medicine of the fellows successfully competed 2010. awards in for grant fellowsof the successfully six above, noted As examination. sub-board Neonatal-Perinatal of Pediatrics’ Board a 95 percent American rate on the success fellowship, fellows and have this workresearch enjoyed during have graduates published one at their from least manuscript United the abroad. To States and in both 95 date, percent of practice, clinical in are half neonatology and academic in career 1980 since chose graduates a 49program of the Half research. clinical basic and in experience develop butteachers, their also and clinicians as not improve only skills program their this Director,in continued Program has to flourish. Trainees of Dr. now direction Luc Brion, the Medicine, under Perinatal Neonatal- in program (ACGME), training three-year the Education for Graduate Medical Accreditation Council by the 2013 accredited through Fully Directors. Program Training Neonatal-Perinatal of Organization the (ABP), and Pediatrics of Board American the Academy of Pediatrics, American the developed ofwas by Dr. Rosenfeld guidelines Charles using Medicine in Neonatal-Perinatal program training The fellowship facility. care tertiary sick preterm of neonate and the to a care prior to transfer how and to provide initial outside the areas, major urban pediatrician general the of requirement common a neonate, sick the of recognition newborn, the of stabilization and in resuscitation skills are to acquire to NICU.provide experiences these theresidents of opportunity The goals Parkland the in infants care and term of preterm daily first- Thethe involvedand second-year in directly residents are premature of neonates. sick and care term initial and triage the in assist and newborns, of term care the in participate Program, the Resuscitation Neonatal in TeamResuscitation Delivery, recertified and Labor are where in they resuscit in expertise with Under of faculty supervision the of Pathology. for Department Series” residents the in Lecture Pathology “Clinical the and Graduate Program, Biology Integrative the in on course Disease” Biologya sophomore “Human and introductory the student course, Medicine,” medical Clinical to “Introduction includes School Medical Southwestern UT at programs multiple within Teaching Medicine. Neonatal-Perinatal and Medicine Maternal-Fetal Gynecology, and Obstetrics Pediatrics, General in for careers to prepare and pregnancies trainees high-risk and normal with the problemsof associated understanding the are to facilitate Gynecology.these and programs of The Obstetrics goals of Department the in Medicine Maternal-Fetal and Medicine, of Division Neonatal-Perinatal the of Pediatrics, Department the School of the Medicine, within play activities prominent educational roles faculty the Division in Presentations/Teaching Activities Network. Neonatal NICHD to the integral is program for 10 existence this more and beenin patients has years of than these database electronic babies. An vulnerable potentially for developmental these and testing intensive services, intervention, education, social through treatment professionals provideDr. healthcare other comprehensive and practitioners, Roy advanced psychosocial Heyne, and medical neurodevelopment. and ofstages chronic diseases theea year,each through 170 life, of three years one new patients. Each being of isfollowed for those first the clinic by the average Weight an of sees patients which 550 to 600 Low Birth of Director Clinic, the Medical He the as nowbasis. serves PA-C, Heyne, 1979 in Dr. by and Elizabeth started Roy to was provide agreed Heyne clinic physician backup on avolunteer The clinic. this be followedthrough can intestines, or disordersorlungs, the chronic who hadspecific neonatal brain, of Babies who were severely Ball. premature (<1500 Charity weight),Center, Crystal birth the gm generously through funded ARCHthe located Lowat Children’s,theof Children) Risk Clinic Weight Birth (Atin apart participates also division The WeightLow Birth Follow-up and Clinic Program ation, third-year pediatric residents are assigned to the the to assigned are residents pediatric third-year ation, Graduating fellow, Dr. Lilian Teng St.John, 1st Day Fellows Research Annual Senior disuccses her researcbh project at the May 2010May rly rly Neonatal-Perinatal Medicine 143 nchez PJ, et al. “Relationship between Dried between Blood “Relationship et al. PJ, nchez hez PJ. “2009 H1N1 Influenza in Hospitalized Infants < 6 Infants Hospitalized in “2009 H1N1 Influenza hez PJ. for Gynecologic Investigation, 2010 Annual Meeting. Meeting. 2010 Annual Investigation, Gynecologic for Orlando, FL, March 2010 (Poster presentation) 2010 (Poster March FL, Orlando, the Ductus of Closure Spontaneous of Prediction CR, Rosenfeld C. “Echocardiographic Ramaciotti P, Punjwani Perinatal Pediatrics, on Section of Academy American of WeeksGestation,” Less 30 Than Arteriosus in Neonates CA, October 2010 Francisco, San Exhibition, and Conference 2010 National Pediatrics, 14th International Mortality,” Infection-Related Reduce and in the Neonate Infections Limit to “Strategies 2010 Diseases, FL, March Infectious Miami, on Congress Network. Research Neonatal NICHD for Subcommittee GDB and BJ, NI, Stoll Hansen PJ, AL, Sánchez Shane (MRSA) aureus (MSSA) Staphylococcus Sensitive and (MRSA) Resistant Methicillin of “Epidemiology Pediatric Network,” Research Neonatal in the NICHD Neonates Birth Weight Low Very Among Infections 2010 BC, May Vancouver, Societies Meeting, Academic Sánc JD, E, Siegel MI, Brock E, Ardura Lopez-Medina 2010 BC, May Vancouver, Societies Meeting, Academic Pediatric Age, of Months Screening PCR for Saliva “Dried et al. PJ, M, Sánchez Z, Michaels N, Novak S, Ross S, Chowdhury Boppana 2010 BC, May Vancouver, Societies Meeting, Academic Pediatric CMV Infection,” Congenital for Newborns M, Sá N, Michaels Z, Chowdhury K, Novak Ross S, Fowler Infection,” Cytomegalovirus Congenital with Infants of Saliva and Load in the Urine Viral and Positivity Spot 2010 BC, May Vancouver, Societies Meeting, Academic Pediatric during in a Child Peramivir of (PK) “Pharmacokinetics MI. Ardura C, Leff PJ, R, Sánchez C, Tucker Garcia (CVVHD),” Hemofiltration Venous-Venous Continuous and (ECMO) Oxygenation Membrane Extracorporeal 2010 BC, May Vancouver, Societies Meeting, Academic Pediatric the NICHD et al for PJ, M, Sánchez Walsh BJ, Stoll I, Bann CM, Goldberg R, D, Benjamin Adams-Chapman Infection,” Candida with Infants ELBW of Outcome “Neurodevelopmental Network. Research Neonatal presentation) 2010 (Poster BC, May Vancouver, Societies Meeting, Academic Pediatric How Therapy: Hypothermia for Infants of “Evaluation PJ. Sánchez MC, R, Morriss Heyne Chalak LF, T, DuPont (HIE)?” Pediatric Encephalopathy Hypoxic-Ischemic Detection of for Examination Good the Neurological Is presentation) 2010 (Poster BC, May Vancouver, Societies Meeting, Academic Mirpuri J, Lin PW, Louis NA. “IL-10 Signaling is Developmentally Regulated and Sensitive to Lactobacillus to Sensitive and Regulated is Developmentally Signaling “IL-10 NA. Louis Lin PW, J, Mirpuri BC, April Vancouver, Societies Academic Meeting, Pediatric Colon.” Murine Developing in (LGG) rhamnosis 2010) Basic Science Award, Fellows 2010 (SPR in the Uteroplacental II Sensitivity Angiotensin Modulating K. “Mechanisms CR, X, DeSpain Rosenfeld, Liu Society Ovine Bed Pregnancy,” throughout Vascular Brion LP. “Duty hours,” Organization of Neonatal-Perinatal Medicine Training Program Directors (ONTPD), (ONTPD), Directors Program Training Medicine Neonatal-Perinatal of Organization hours,” “Duty LP. Brion CA, October 2010 Francisco, San Biochemical States United “Texas, PJ. ChristieJ, L, Sanchez Burchfield MC, Morris LP, Brion Chalak LF, to the Late Apply Do They How Encephalopathy: Ischemic Hypoxic of Assessment for Criteria Screening Hypoxic-Ischemic for Hypothermia of Implementation Societies Meeting: Academic Pediatric Infant?” Preterm presentation) 2010 (Poster BC, April (HIE), Vancouver, Encephalopathy Therapy: Hypothermia for Infants of “Evaluation PJ. Sanchez MC, R, Morriss Heyne TL, Chalak LF, DuPont (HIE)?” Encephalopathy Hypoxic-ischemic Detection of for Examination Good is the Neurological How Encephalopathy Hypoxic-Ischemic for Hypothermia of Implementation Societies Meeting: Academic Pediatric presentation) 2010 (Poster BC April (HIE), Vancouver, of Life Hour 1st the Within “Hyperoxemia M. L, Christie L, Wyckoff Brion T, Dupont Chalak LF, V, Kapadia Academic Pediatric HIE,” Moderate-severe of development Subsequent and Asphyxia Perinatal Following (HIE) Vancouver, Encephalopathy Hypoxic-Ischemic for Hypothermia of Implementation Societies Meeting: 2010 BC, April Epic and Neonatology: A Bright Beginning. Co-presented with Renae Muhammad, RN, Epic User Group Group User RN, Epic Renae Muhammad, with Beginning. Co-presented A Bright Neonatology: and Epic 2010 September WI, Verona, Meeting, “Insights into BPD: The Inflammation Superhighway: Tolls, Signals and Pathways,” Jerry Memorial Elliot Pathways,” and Signals Tolls, Superhighway: Inflammation The BPD: into “Insights 2010 FL, March West, Key Lecturer, of the Regulation into Insights Novel Immunity: Innate & Matrix Extracellular Surfactant, “Pulmonary 2010 March TN, Nashville, Conference, Research Pediatric Vanderbilt Inflammation,” Lung Development,” of an Arrest and Inflammation into Insights Dysplasia: New “Bronchopulmonary 2010 March TN, Nashville, Rounds, Grand Pediatric Vanderbilt and Inflammation 2010 HA Injury,” Lung Bleomycin-induced after Protected are Mice Knockout “RHAMM 2010 June Japan, Session, Kyoto, Immunity t t t t t t t t t Pablo J. Sánchez, M.D. J. Pablo Charles R. M.D. Rosenfeld, t Julie Mirpuri-Hathiramani, M.D. Mirpuri-Hathiramani, Julie t t t t Lina Chalak, M.D. t t M.D. Brion, P. Luc Timothy Brannon, M.D. Brannon, Timothy t t t Rashmin M.B.,Ch.B. Savani, C. t 144 Neonatal-Perinatal Medicine t Myra Wyckoff, M.D. t t t t t t t t t t t t t t t t t t t UT Southwestern faculty are consistently highly ranked for Southwestern consistentlyUT are ranked faculty highly and Treatment Recommendations Conf Outcomes International (O)?” Consensus on Cardiopulmonary and Cardiovascular Emergency Care Science “In Neonates Receiving ChestCompressions Ratios (5:1,15:2)(I)versus Other (P),Do 3:1(C)Improve Perinatology, RiodeJaneiro, Brazil, November 2010 “Congenital CMV: State of Art,” the “Congenital Syphilis: ABig Challenge,” Brazilian Congress XX of Neonatology Annual 2010,34th International Conference, FL,November Miami Beach, 2010 “Congenital CMVand Herpes Infections: AnUpdate,” “Strategies inPreventing Neonatal Infections,” Miami Pediátrica yVacunas, Buenos Aires, Argentina, 2010 October “SífilisCongénita, un Problema PersistenteLatina,” enAmérica Congreso II Internacional de Infectología of Vancouver, America, Society Disease 2010 October BC, and Skin Recurrences Following Neonatal Herpes Simplex Virus Disease,” Annual 48th Meeting, Infectious Collaborative Antiviral Study Group, “Impact of OralAcyclovir Suppression on Neurodevelopmental Outcomes Kimberlin DW, Whitley RJ, Wan W, Powell DA, Storch G,AhmedA,Palmer A,Sánchez PJ, etalfor NIAID the Medical Center, Albany, NY, September 2010 (HSV) Infection: Another TORCH?” Capital Pedi District “Congenital Cytomegalovirus Infection,” Grand Rounds, “Congenital Syphilis,” “Neonatal Herpes Simplex Virus Congénitas,” Curso Internacional XXII dePediatría, Viña delMar, Chile, September 2010 “Sospecha ClinicayDiag Time to Treat” Grand Rounds, Oregon Health University &Science (OHSU), Portland, Oregon, June 2010 “Neonatal Infections: Improvement Needed!” Oregon Neonatal and “Congenital Series Seminar CMVInfection: Pediatric Academic Meeting, Societies Vancouver, May BC, 2010(Poster presentation) Assessment of Hypoxic-Ischemic Encephalopathy (HIE):How They Do ApplyLatethe to Preterm Infant?” Chalak LF, Brion LP, Morriss MC, Burchfield L,SánchezJ, Christie PJ. Screening“Biochemical Criteria for Central ConferenceCentral on Perinatal Research, San Francisco, 2010 CA,October Program (NRP)Recommendations for Epinephrine Usage Room,” inDelivery Mead Johnson Nutritionals South Sparks JE,Jaleel L,Brion MA,Christie LP, Wyckoff, MH. “Impact of Changesthe 2006 in Neonatal Resuscitation 2010 October Room Management“Delivery and Initial Stabilization of ELBW the Infant,” 2010 NCE AAP, San Francisco, CA, Seminar, 2010NCE AA,San Francisco, 2010 CA,October Workshop-basic Simulation and Set-up Facilitation, Neonatal Resuscitation Program (NRP)Current Issues Perinatal Research, Austin, 2010 October TX, “Prevention of Hypothermia for Preterm the Infant Room,” Delivery inthe 2010South Conference Central on Excellence inNewborn Medicine of Australia, Vancouver, May BC, 2010 Workshop, Sponsored by National the Health and Medical Research Centers Council of ClinicalResearch “Impact Room of CPRon Delivery Outcome the of Preterm Infants,” Neonatal Resuscitation Research Academic Meeting, Societies Vancouver, May BC, 2010(Poster presentation) Compression:ventilation Ratio 15:2versus 3:1inNewborn P I,Wyckoff AL,Dannevig Solevag MH,Saugstad OD, Nakstad ”Return B. of Spontaneous Circulation with Vancouver, May BC, 2010 Hyaluronan and PlasmaTumor Necrosis Factor Alpha Expression,” Pediatric Academic Meeting, Societies Resuscitation with 100%Oxygen isAssociated with Increased Lung 2-nitrotyrosine, Low Molecular Weight Osterholt HCD, I,Wyckoff Dannevig Liao MH, J, Nakstad SaugstadB, OD, Savani RC. “Newborn Piglet Preterm Neonates,” Pediatric Academic Meeting, Societies Vancouver, May BC, 2010(Poster presentation) St. John LT, LH,Wyckoff Christie Room Risk MH. “Delivery Factors forDevelopmentthe of in Hypothermia DR Questioned,” Pediatric Academic Meeting, Societies Vancouver, May BC, 2010 Perinatal Asphyxia and Development of Moderate to HIE:Use Severe of 100%Oxygen during Resuscitation in Kapadia V, Dupont T, ChalakL,Brion L,Chirstie L, Conference, CA,February 2010 Newport Beach, “Neonatal Resuscitation: Airway/Breathing” and “Neonatal Resuscitation: Compressions/Drugs,” NeoPREP 2010 CardiovascularEmergency and Care Treatment Science to aTwo Finger Technique (C)Improve Outcome International (O)?” Consensus on Cardiopulmonary and “For Newborns Receiving ChestCompressions Use the (P)Does of aTwo Thumb Technique (I)asOpposed nóstico Diferencial deTORCHS,” “Tópicos enelTratamiento deInfecciones Teaching Excellence erence, Dallas, TX, February 2010 erence, TX, Dallas, Wyckoff MH. “Hyperoxemia within First Hour Lifeof in Recommendations February Conference, TX, Dallas, atrics Conference, Pfizer Visiting Professor, Albany by medical students,by medical residents fellows. and igs with Cardiac Arrest Dueto Asphyxia,” Pediatric Neonatal-Perinatal Medicine 145 emistry, American Journal of Physiology-Lung Cell and Cell and Physiology-Lung of Journal American emistry, esidency Program, UT Southwestern/Children’s esidency Program, . Member, Nominating Committee, Society for Pediatric Research Society Pediatric for Committee, Nominating Member, of Diseases, Academy Infectious American on 2009 Red Book: the Committee Report (Syphilis), of Collaborator, Pediatrics Parkland Nursery, Newborn Co-Director, R Pediatric Director, Program Associate Associate Editor, Early Human Development Human Early Editor, Associate Society Pediatric Texas Diseases Immunizations, Infectious and of Committee Chair, Diseases Infectious in Children Board, Advisory Editorial Member, Drug and Food (VRBPAC), Committee Advisory Products Biological Related and Vaccines Member, (FDA) Administration Review Panel (CHHD-A) Subcommittee Pediatrics NICHD Member, Medical Director, Campus-wide Epic Systems Applications (Electronic Medical Records) Implementation for for Implementation Records) Medical (Electronic Applications Systems Epic Campus-wide Director, Medical Medicine Neonatal-Perinatal of Division Course Physiology Fellows’ Neonatal Director, Pediatrics Fellows, Subspecialty for Curriculum Core Department Director, Sciences Reproductive Editor, Associate Co-director, Newborn Nursery, Parkland Nursery, Newborn Co-director, NNICU Parkland Director, Medical Committee Practice Joint ICU Neonatal Parkland Chairman, Committee Improvement Quality (NPIC) Center Information Perinatal National Member, Program Practitioner Nurse Neonatal Director, Medical Medical Director, Low Birth Weight Clinic Birth Weight Low Director, Medical Children’s Management, Resource Quality Director, Medical Center Development Birth Weight Low Directors, Board of President, Vice Center Development Birth Weight Low Committee, Finance Chair, Children’s Safety, Patient Quality Chair, Children’s Review, Quality Chair, Children’s Management, Clinical Resource Chair, Director, Fellows Mortality and Morbidity Conference, UT Southwestern Conference, Morbidity and Mortality Fellows Director, UT Southwestern Course, Medicine Evidence-Based Neonatal-Perinatal Co-director, UT Southwestern Conference, Resuscitation Neonatal-Perinatal Co-director, UT Southwestern Medicine, Neonatal-Perinatal Officer, Compliance Billing Member, Editorial Board, Journal of Perinatology of Journal Board, Editorial Member, Cochrane Collaboration Member, Oncology; in Radiation Programs Review Training of Internal Sub-Committee: Education Medical Graduate PulmonaryNephrology; Disease, and UT Southwestern Center Medical Children’s Committee, Directors Program UT Southwestern Course, Medicine Evidence-Based Neonatal-Perinatal Co-director, Molecular Physiology, and Journal of Angiogenesis Research Angiogenesis of Journal and Physiology, Molecular Clinical Investigation of Journal Board, Editorial Consulting Member, District Medical Southwestern Team, Development EMR EPIC Neonatal Lead, Campus Medicine in Neonatal-Perinatal Program Training Fellowship Director, Directors Program Medicine Neonatal-Perinatal of Organization Council Member, Director, Division of Neonatal-Perinatal Medicine, UT Southwestern Medicine, Neonatal-Perinatal of Division Director, UT Southwestern Biology, Vascular Pulmonary and of Division Director, Associate Parkland Medicine, Neonatal-Perinatal Service, and Chief of Pediatrics Center Medical Children’s Medicine, Service,Chief of Neonatal-Perinatal Ch Biological of Journal Board, Editorial Member, Dorothy Sendelbach, M.D Dorothy Sánchez, M.D. J. Pablo Charles R. Rosenfeld, M.D. Charles R. M.D. Rosenfeld, Mambarath Jaleel, M.D. M.B.A M.D., Gregory L. Jackson, Roy J. Heyne, M.D. J. Roy M.D. Engle, D. William LinaChalak, M.D. Timothy Brannon, M.D. Brannon, Timothy M.D. Brion, P. Luc Major Administrative or Leadership Responsibilities Administrative Major Rashmin M.B.,Ch.B. C. Savani, 146 Neonatal-Perinatal Medicine D.O.,Audra Stewart, M.P.H. Pablo J. M.D. Sánchez, Julie Mirpuri-Hathiramani, M.D. William D. Engle, M.D. M.D. Chalak, Lina Luc P. Brion, M.D. C.Savani, M.B.,Ch.B. Rashmin /AwardsHonors Myra Wyckoff, M.D. W.Philip Shaul, M.D. Certificate of AppreciationTX forthe Health Steps Provider Education DSHS)Program (TX Member, Texas &Hard Deaf of Hearing Leadership Council AAP Chapter Champion (Texas), Early Hearing and Detection Intervention (EHDI) PediatriciansBest Pediatric inDallas, Infectious Diseases, Young Science Basic Investigator Award, for Pediatric Society Southern Research Fellow’s Research Science Award, Basic for Pediatric Society Research Member, &Reimbursement Coding Committee, AAPPerinatal VII) (District Section VIIRepresentative,District AAPPerinatal Executive Section Committee NIH Young Investigator Travel Award, Perinatal Research Society Clinical Research Scholar, Department UTSouthwestern, of ClinicalSciences, 2008-2011 inAmerica Doctors Best Member, Organization of Neonatal-Perinatal Training Program Directors (ONTPD) Elliott Memorial Lecturer,Gerry Perinatal Southeastern Research Conference 2010 March of DimesPhysician Excellence Award (Texas) Co-director, Neonatal-Perinatal Evidence-Based Medicine Course, UTSouthwestern Academic Mentor, Pediatric Program Residency Member, International Liaison Committee on Resuscitation, Neonatal Working Group, American Heart Association Member, Neonatal Resuscitation Program Steering Committee, American Academy of Pediatrics Director, Neonatal-Perinatal Resuscitation Conference Director, Parkland Newborn Resuscitation Services, Member, Newborn Screening Advisory Committee, Texas 81stLegislature Chair, International of Board Consultant Lactating Examiners, 2012Exam Development Committee Stehel, M.D.Elizabeth Member, Ph.D.Committees Thesis Member, Exam IBQualifying Committees Member, Steering Committee, University UTSouthwestern Lecture Series, Graduate of School Biomedical Sciences Member, Steering Committee, Medical Scientist Training Program, Southwestern Medical Southwestern School, Director, Division of and Pulmonary Vascular Biology, UTSouthwestern D Magazine Nephrology 147 Michel G. Baum, M.D. Director, Pediatric Nephrology Pediatric Director, Pediatric Nephrology divisions in divisions the nation Nephrology Pediatric Nephrology one of the top 20 top the of one Recognized as Faculty the and of Pediatric Director Nephrology is Professor G. M.D. Baum, Michel the Sarah holds Division. He M. and Charles E. Chair Seay in Pediatric Research. clinical expertise Baum’s kidney is in chronic disease,Dr. dialysis, nephrotic syndrome, renal transplantation, tubular and disorders renal tubular acidosis. epithelialHis on research transport, interests are centered renal development, and tubular areas maturation the study of disorders. Recent Na+/ of involve in exchanger the proximalits role H+ tubule,and growth fibroblast factor-23 in wasting UCLA in diseases, phosphate hyposphatemia and X-linked the prenatal from degree medical his programming Baum graduated hypertension. adult summa of Dr. cum laude received He 1974. California in from of the University Los at Angeles with Science the of a Bachelor biochemistry in degree Nephrology, from Hospital Haven and performed his pediatric1978 Yale-New at residency University Renal Pediatric the Center, performed at Children’s fellowships He 1981. to 1978 of and Editor 1982, to Californiaof San 1981 in from at Francisco, Pediatric Nephrology is He California of the in San Cardiovascular at at Francisco, University Institute, Section. has been listed He 1984. to of asNephrology and one Renal from 1982 Physiology Study NIH an the Best Doctors in America from 2002 and the serves to present as a permanent of member journal has the Beta Phi been elected He of to International Kappa, Alpha Society Omega Pediatric Nephrology. of Alpha, the American Society Clinicalfor the Investigation, American Association of the Physicians, Society for Pediatric Research, and the American Pediatric Society. Dr. Michel Baum is the Editor of Pediatric Nephrology, the journal Baum the is the Michel Pediatric of International Nephrology, of Editor SocietyDr. PediatricNephrology. of the of divisionMembers editorial are the on and American the boards Pediatric of Nephrology, Journal Physiology, of Journal the of American Society Nephrology. of The research productivity of the Nephrology division is outstanding. Members of the division publish both clinical clinical both publish division the of Members outstanding. is division Nephrology the of productivity research The and research basic manuscripts in the journals. prestigious Nephrology most Division faculty been continuously have funded than the by more NIH 20 years. for There are usually six Nephrology fellows in training at a time, each being mentored in both clinical nephrology and and nephrology clinical both in mentored being each a time, at training in fellows Nephrology six usually are There clinical either or basic the given by American the Research research. Several been presented Award the have of fellows are trainees and some Society an Pediatric of Nephrology, NIH-funded of training grant, the of very in few the one Program was a Pediatric awarded Scientist Development M.D., Matthias fellow Wolf, 2nd-year In 2010, country. grant, pediatricians grant a competitive only to 5-7 awarded manuscript annually. in All a first-author have fellows a leading their journal and graduating of most fellowship, the by completion trainees careers productive continue in academic medicine. Specializing in all diseases, areas renal-related including of inherited renal kidney disorders, chronic disease, urinary tract infections, hypertension, tubular abnormalities, renal tubular disease, and metabolic bone acidosis Nephrology outstandingoffers services enables state-of-the-art provide that the physiciansto division equipment care.and The care with patients to provide stage renalend disease, the of largest pediatric is one and it hemodialysis, peritoneal dialysis and transplant programs States. in the United The Division of PediatricNephrology of is Division clinicalof mainThe the provider services childrenfor withrenal disease and hypertension at Children’s. TheNephrology inpatient and outpatient services, comprised of physicians,nurses and staff, dedicated to childrenof are the treatment with these diseases. 148 Nephrology University of Washington, Seattle Children’s Hospital, Fellow, Pediatric Nephrology, 1998-2001 Pediatrics, 1984-1988;New York University Medical Center, Resident, Pediatrics, 1995-1998; Post-doctoral training: Valhalla, Ph.D., 1995 Clinical expertise: Clinical Assistant Professor Amy Becker, M.D., M.S.C.S. 2007; UTSouthwestern, Fellow, Pediatric Nephrology, 2007-2010 Post-doctoral training: Charleston, M.D., 2004 Education: expertise: Research expertise: Clinical Assistant Professor Katherine Twombley,M.D. Resident, Pediatrics, 1986-1987;Fellow, Pediatric Nephrology, 1984-1986 Resident, Pediatrics, 1983-1984;Georgetown University Medical Center, Washington, DC, Post-doctoral training: Education: X-linked hypophosphatemiadisease, and focal segmental glomerulosclerosis (FSGS) expertise: Research inchildren, hypertension, pediatric disease renal pediatric transplant expertise: Clinical Professor Mouin G.Seikaly, M.D. Southwestern, Fellow, Pediatric Nephrology, 1988-1991 Post-doctoral training: Medicine, Birmingham, M.D., 1985 Education: metabolites inrenal function expertise: Research transplantation, tubular disorders, renal tubular acidosis expertise: Clinical Professor Raymond P. Quigley, M.D. Education: expertise: Research expertise: Clinical Associate Professor Fangming Lin,M.D., Ph.D. Pediatrics, 2003-2005;UTSouthwestern, Fellow, Pediatric Nephrology, 2005-2009 Post-doctoral training: 1994 Education: expertise: Research expertise: Clinical Assistant Professor Jyothsna Gattineni, M.D. 2000-2003; UTSouthwestern, Fellow, Nephrology, 2003-2006 Post-doctoral training: Southwestern, M.D., 2000;M.S.C.S.,2009 Education: expertise: Research inchildren with disease inbornkidney errors of metabolism College of Charleston, SC,B.A., 1996; Medical University of South Carolina, American University Lebanon, of B.S.c., Beirut, 1976;M.S.c, 1981 Auburn University, Auburn, AL,B.S., 1979;University of Alabama of School Fujian Medical College, Fuzhou, C Stanley Medical College, MGR University, Chennai, Tamilnadu, India, M.B.B.S., Methodist Southern University, B.S., laude, summacum TX, Dallas, 1995;UT Chronic nephrotic disease, kidney Chronic dialysis, renal disease, transplantation, kidney metabolicbone dialysis, endstage renal Chronic disease, disease, kidney Hematuria, proteinuria, renal ge Chronic dialysis, hypertension, disease, kidney renal transplantation Transplant, dialysis, chronic endstage renal disease disease, kidney RenalStone Disease Metabolic and growth bone disease inchildren with chronic kidney Development of renal water transport, effects of arachadonic acid Stem celltherapy for acute injury kidney Tubular transport, FGF23and its receptors Sickle cellnephropathy Miami Children’s Hospital, FL,Intern and Resident, Pediatrics, 2004- American University Resident, of Beirut, Pediatrics, 1980-1983; Chief Driscoll’s Children’s Hospital, Intern CorpusChristi, TX, and Resident, Cincinnati Children’s Hospital Medical Center, Resident, Pediatrics, Fujian Medical College Union Hospital, Fuzhou, China,Resident, UT Southwestern/Children’s, Resident, Pediatrics, 1985-1988;UT hina, M.D., 1984;New York Medical College, netics, polycystic kidney disease kidney netics, polycystic syndrome, renal endstage disease, Nephrology 149 May 25, 2010 May Annelise Ribeiro, M.D. Annelise Ribeiro, Research Interests: kidney injury acute of Outcomes Catherine J. Kottukapally, M.D. Kottukapally, J. Catherine Research Interests: acidification Renal M.D. Khurrum Siddique, Research Interests: of programming Prenatal hypertension Katherine Twombley, M.D. Twombley, Katherine UT Southwestern Professor, Assistant Research Interests: tubule proximal of Maturation acidification 1st Annual Senior Fellows Research1st Day Graduating fellow with Katherine Twombley Dr. Jeffrey ResidencyMcKinney, Dr. Program Director Modini Vinai, M.D. Vinai, Modini UT Southwestern Instructor, Research Interests replacement renal of Outcomes therapy Sabeen Habib, M.D. Sabeen Habib, State Louisiana Professor, Assistant Science Center Health University Research Interests: of programming Prenatal hypertension Pamela Winterberg, M.D. Winterberg, Pamela Research Interests: immunology Transplant Diana Zepeda-Orozco,Diana M.D. Research Interests: obstructive of uropathy Pathogenesis Matthias Wolf, M.D. Wolf, Matthias Research Interests: of forms inherited of Pathogenesis hypertension In 2010, Dr. Matthias was a grant awarded Dr. Wolf In 2010, from the Pediatric Scientist Development Program from the Pediatric Development Scientist This provides granthis salary$20,000 (PSDP). plus per year through 2012. June awarded grantThis is PSDP annually competitive to pediatriciansonly 5-7 in the nation. 2nd Year 2nd Year Year 1st 3rd Year 3rd Post-doctoral Fellows Fellows Post-doctoral 2010 Completed June 150 Nephrology procedures per month year. last 41 and continuous treatments venovenous 52 dialysis treatments, acute peritoneal acute hemodialysis hemofiltration average at Children’s, an of performed 16 division the for services intensive sole consultants the care the renal As and hypertension. treatmentdisease thefloorand are of physiciansto whoby dedicated renal nurses same thetreated patients on all of census with a mean has patients, 11 Service inpatient The Nephrology Pediatric country. the in theprograms one largest ours of making per performed year There transplants annually. were 27 renal dialysis homewith treated peritoneal and34 patients an There patientsaverage is of 30 hemodialysis dialysis. peritoneal program dialysis is The peritoneal dialyzed. provides being environment laptop are that they computersfriendly while to children staffed Texas.bydays North a unit, at which in isachild- week, outpatient isperformed six The hemodialysis hemodialysis devoted disease end renal stage provider with for children healthcare primary the and disease, end renal stage with children physiciansthe treatment in theUnited States for of Southwesterntheprograms is UT largest onedivision at The Nephrology and nurses dedicated Activities Clinical to the families treating Children’s.and children Association Heart for American the isprovided research Funding bone NIH, by the disease. patients with in studies with outpatient bone debilitating Investigators and disease. disease kidney Finally, isaconnection between there be successful. will transplant akidney that improve and likelihood the dialysis howimprove to on livesthe of children examining studies conductsdivision clinical The dialysis. suchas therapy to severe disease. mild renal in result that kidney of the diseases of inherited utero happen that in or because of kidney. because each insults in However, occur that kidney of the diseases are there nephrons called units of nephrons kidney one isachieved at million 35 isborn with gestation. child weeks Ahealthy complement developingfull theat and starts kidney gestation, 10 weeks The children. in disease treatment of kidney pathogenesis and the at understanding aimed are Nephrology of Division Pediatric of the activities Research Research Activities Associate Research Zhang, Qiuyu Waber, G. Pamela Coordinator Study Research M.S., [Ling]Linda M.D., Li, Ph.D., Fellow Research Postdoctoral Associate Research M.S., Vangipuram N. Dwarakanath, Bradshaw,Sam Tech Research B.S., II Tech Research Black,B.S., Rachel II ResearchClinical Staff disease causesdisease permanent loss of and function requires kidney extensive renal Sometimes bone stem cells. using marrow injury of acute kidney noveltreatmentsimprove to theare examining outcome They disease. causeand bone D levels vitamin homeostasis, electrolyte renal affect how hormones FGF-23 suchas Investigators Klotho examining are and isamajor disease. of injury cause chronic kidney acute kidney and two decades the past over not has improved injury significantly kidney injury. The prognosis to kidney acute for leads acute that kidney to the blood supply the in interruption orbe injured by an nephrotoxic drugs develops normally, kidney Even it can the if disease. kidney polycystic developmentkidney affect as such that autosomal recessive diseases inherited examine also They later life. in hypertension and disease kidney in result insults prenatal how determine to works faculty The have taken basic discoveries made at the bench to clinical basic bench discoveries madeathave to the clinical taken Nephrology 151 ” 42nd Kenneth C. Haltalin Pediatrics for the Practi- for Pediatrics C. Haltalin ” 42nd Kenneth “Prenatal Programming of Hypertension,” University of California, San Diego, February 2010 February Diego, San California, of University Hypertension,” of Programming “Prenatal 2010 May Society Nephrology, “Chinese of Hypertension, of Programming “Prenatal 2010 China, May Guangzhou, University, Yat-Sen Sun Receptors,” its and “FGR23 American 43rd Kidney Injury,” Acute Cells Treat to Progenitor and Stem Hematopoietic of “Reprogramming presentation) 2010 (Poster November CO, Denver, Meeting, Annual Society Nephrology of Tyler, Science at Center UT Health Rounds, Grand Pediatric the Primary Pediatrician,” Care for “Hypertension 2010 April Meetings, (IPNA) Association Nephrology Pediatric International 15th Annual Acid-Base,” of “Fundamentals 2010 September NY, York, New 2010 Dallas TX, Children, June for Hospital Rite Scottish Texas Bone Disease in Children,” “Metabolic anOld Disease, D Deficiency: For New Concepts “Vitamin tioner Annual Seminar, UT Southwestern, April 2010 April UT Southwestern, Seminar, Annual tioner 2010 Beirut, April of Lebanon, University American Bench Bedside,” to From in Children: “XLH Diego San Sunrise Symposium, Congress, Transplant American Renal Transplant,” FSGS Post of “Management 2010 CA, May 2010 September Center, Medical in Dallas, Children’s Renal Transplant Pediatric of “History LA, December 2010 Shreveport University, State Louisiana An Update,” Renal Transplant. “Pediatric NY, City, York New Medical Weil College, Cornell an Old Disease,” D Deficiency:For New Concepts “Vitamin December 2010 Dallas, TX, DFW, of Network Dietitian Pediatrics Old Disease,” an D Deficiency:For New Concepts “Vitamin December 2010 t t Lin, M.D. Fangming t M.D. Quigley, Raymond t t M.D. Seikaly, Mouin t t Michel Baum, M.D. Michel Baum, t teaching with every patient and a formal discussion of a topic. We also participate in teaching of internal medicine The medicine division internal of of nephrology teaching in provides participate teaching also We to and the at Medicalmedical are rounds Nephrology accompanieddiscussions by School. Children’s in at topic. formal conferences a of students, discussion interns, formal a and residents patient every and with fellows.teaching We provide didactic and pediatric UT at Southwestern. nephrology fellows Presentations/Teaching Activities Presentations/Teaching t t t t t t During 2009 - 2010 there was a monthly average of about 450 outpatients. Over plans expanding the 450 outpatients. include next about During year, of there was a monthly average 2009 - 2010 servicesoutpatient and in patients the accommodate physicians to Dallas. private The PediatricThe Nephrology Clinic at Children’s Dallas is now inoperation at and clinics been initiated through Children’s at have Friday, Monday In the additionLegacy. to clinical doctors Children’s, responsibilities at Scottish Children, Rite Dr. Texas for Hospital at see patients where Seikaly Clinic. is the the Bone Director of Metabolic Dr. Baum, along with Mouin Seikaly,Dr. Drs. Quigley, Amy Raymond Becker, Jyothsna Gattineni,Fangming Lin, provided and Katherine Twombley the attending inpatient responsibility thePediatric for Nephrology service In responsibility months. addition to the for 12 previous over and Parklandproviding Children’s consults with Memorial at Hospital, consults the attending month, per inpatient 21 an of provides average the majority teaching of students, and during residents, for fellows the they service.month are on 152 Nephrology Mouin Seikaly, M.D. Mouin Seikaly, M.D. Raymond Quigley, M.D. Fangming M.D. Lin, Amy Becker, M.D., M.S.C.S. Michel Baum, M.D. Awards andHonors Michel Baum, M.D. Major Administrative Responsibilities orLeadership Lead GuestLead Editor, International Journal of Pediatrics. Hindawi Publishing Cooperation Associate Editor, Dialysis and Transplantation, Wiley Periodicals Inc Editorial Board, World Journal of Transplantation Baishideng Publishing Group Co., Limited Editorial Board, Pediatric Nephrology, Springer Verlag ,Heidelberg Germany Presidential Who isWho Marquis Who isWho inAmerica Guide to America’s Pediatrician Best Texas Super doctors inAmerica Doctors Best PediatriciansBest inDallas, Editor-in-Chief Pediatric elect Nephrology Texas Superdoc inAmerica Doctors Best Member, Abstract Committee, Review American Transplant Congress Member, Pediatric Accreditation Committee, of Transplant American Society Member, Participating Centers Committee, North American Pediatric RenalTransplant Cooperative Study Co-director, Dialysis Program, Children’s Medical Center Director, Clinic,Texas Metabolic Disease Bone Scottish Rite Hospital for Children Medical Director, Pediatric RenalTransplant, Children’s Medical Center Director, RenalTesting Children’s Services, Medical Center asMentorServed for eight house staff officers Medical Director, Camp 2005-present Reynal, (Camp for RenalPatients Sponsored by NKFof the North Texas) Medical Director, Dialysis Unit, Children’s Medical Center, 2006-present Associate Editor, Pediatric Nephrology Director, AnimalModels Core of O’Brien UTSW the Center Kidney of Nephrology and Membership Committee, Society American TheChinese Member, of Board Directors, and Chair of Communication of NephrologySociety Annual Meeting Proliferation, Apoptosis, and Neoplasia”, American the Abstract Category Chair in“Cell Signaling: Growth, Cell Director, Pediatric Nephrology Fellowship Program Nephrology Editor,Section Urinary Tract Disorders, Pediatric Southwestern Member, Promotion and Tenure Committee, UT Journal of Physiology Member, RenalPhysiology Editorial Board, American Councillor ExOfficio, InternationalSociety of Nephrology of Pediatric Nephrology Member, Program Directors Committee, American Society forReviewer Repayment NIHLoan Awards Hematologic DStudy 2009 Diseases Section Member, NIHStudy NIDDK, Kidney, Urologic and Renal Editor, Current Opinions inPediatrics Editor, Pediatric Nephrology Director, Pediatric Nephrology D Magazine 1st Annual Senior Fellows Research Day Research Fellows 1st Senior Annual Graduating fellow Sabeen Habib with Sabeen fellow Graduating Dr. department’s atthe Michel Baum May 25,2010 Neurology 153 Director, Pediatric Rheumatology Pediatric Director, Susan T. Iannaccone, M.D. Iannaccone, SusanT. Neurology Faculty is the Jimmy Elizabeth Professor, Westcott Iannaccone, M.D., Susan T. Distinguished Chair in Pediatric Neurology and the Director of Pediatric clinicalNeurology program Iannaccone’s UT at interests Southwestern. Dr. are focused on neuromuscular spinal and medicine (DMD) and neurorehabilitation. dystrophy muscular Her research Duchenne in trials clinical includes muscular She atrophy. was Principal Investigator for American Spinal Muscular Atrophy Randomized Trials (AmSMART), 2000 to 2008, with funding from the II a Phase Institutes National include Health of projects Current (NIH). inclinical and DMD a registry establishment of trial for (ataluren) PTC124 of heredity neuropathy. Iannaccone Dr. received her medical degree from State performed Syracuse, She Health Science Center, in 1969. York New of University Upstate training residency her in York pediatrics New of the University at State and St. Louis at Medical Syracuse, 1971 to Hospital, University from 1969 was She a 1972. to from 1971 University, Washington Hospital, Children’s in theresident neurology department Memorial Strong of Hospital, University 1975. to from 1972 York, New Rochester, of efficiently. Thus, referrals to the PN Clinic are reviewed weekly to determine the appropriateness of the referral and referral the of appropriateness the determine to weekly reviewed are The providingcommitted is division to high-quality timeframecare in utilizingappropriate to an Clinic and PN resources the to referrals Thus, efficiently. to ensure that the neurologistreceives supporting records and documentation. Attending neurologists are available answer24/7 to any regarding questions referrals guidance and provide to general to practitioners and pediatricians. Each year, the and the division, inEach Muscular with year, collaboration Children’s Dystrophy the Department Neurology, of the Carrell-KrusenAssociation, presents Iannaccone is the Neuromuscular Program Dr. Symposium. Director for this meeting from and the fellows division and residents most and from the Department Neurology of participate by presenting the at symposium. An integrated six-year program is available for training in Pediatric Neurodevelopment (PND). One candidate One is programAn training is available integrated six-year for (PND). in Pediatric Neurodevelopment everyaccepted this other year for program. training Fellowship sub-specialties PN for is available in the division for epilepsy and neuromuscular medicine. This but training of residency PN yearthe one available completion is for after a research completes a year research. cases two Eachin of include resident years to be extended some for in may order national meetings more or during one at their and presents project 3 year training. The national shortage of pediatricand this the Child For a high the reason, Neurology Society. divisionpriority maintain for is to Pediatric a competitive neurologists has been deemed TrainingNeurology (PN) Program that will high-quality supply help a faculty many residents crisis years PN for come. to by both the American two years entering pediatric the of complete program. before residency PN The training is yearsthree duration in Academy of Neurology fulland one includes Beginning Neurology. year Adult of in 2009, the Department Pediatrics of medical offered students an opportunityyears of five training for so that both they canPediatric complete their PN trainingand at UT Southwestern. There residents, are PNnine threeyear. seesEach per ownhis/her patients in weeklytheir PN there areContinuity two CCs each staffed Clinic per week, by faculty. TrainingIn (CC); two 2009 PN the Program, under the Rana direction Said, Dr. of achieved fullyears, five a the from rare accreditation for ABPN excellent and alltribute of the to in hard work the involved program. Dr. Susan became Iannaccone ChiefDr. in Division 2004, and the the division Department joined Pediatrics in of 2006. facultyThe a mixrepresents young of mature and individuals,brings special whom of each talents experienceand further to contribute to that promise the of division. growth Additional faculty and development are being recruited join theto team. The Division of Pediatricof DivisionNeurologyThe represents an academicpractice with to commitment patient care, teaching and inresearch. Formed the as 1980s part the the of division Department maintained Neurology, of a successful academic and training program through the 1990s. 154 Neurology 1994-1995 and 1998-2000 Foundation, OH, 1993-1994; Resident, Clinic Cleveland Pediatrics, Fellow, Neurology, Child Nutrición, City, Mexico Fellow, 1986-1988; Texas Tech University, Paso, Resident, El 1991-1993; Post-doctoral training: Education: expertise: Clinical Professor,Assistant Neurology and Pediatrics Jose Luis Aceves, M.D. Neurology, 2006-2008; Fellow,Neurology, 2007-2010 Neurodevelopmental 2006-2008; Disabilities, Southwestern, UT FellowNY, Pediatric 2003-2004; University of Buffalo, Resident, Pediatrics, Post-doctoral training: Education: disabilities learning autism and young girls, in dystrophinopathy episodes, Research expertise: delay expertise: Clinical Professor,Assistant Neurology and Pediatrics Sailaja Golla, M.D. Development,Cognitive 1995-1996 1992-1995; MD, Baltimore, School Institute, Johns Hopkins ofKennedy Krieger Medicine, 1983-1986;Residency, Neurology, Pediatrics, Resident, Pediatric Southwestern, Adult and UT Post-doctoral training: Center, Lubbock, M.D., 1983 Education: Research expertise: expertise: Clinical Professor,Associate Neurology and Pediatrics M.D. Evans, Patricia Southwestern/Children’s, Neurology, Resident, Pediatric 1997-2000 Post-doctoral training: M.D., 1995; Southwestern, UT M.S.C.S., 2009 NY, Ph.D., 1994; Columbia University of College Physicians Surgeons, New and York, NY, Education: stroke, Sturge-Weber pediatric disease, cell sickle stroke in syndrome Research expertise: complications disease of cell sickle expertise: Clinical Professor,Assistant Neurology and Pediatrics F.A.H.A. Dowling,Michael Ph.D., M. M.D., M.S.C.S., 1994-1996 Epilepsy/Neurophysiology, Pediatric Neurology, 1992-1994; MO, Washington University Fellow, Louis, St. School of Medicine, 1991; Resident, Neurology, 1991-1992; Children’s Louis St. Hospital, MO, Resident, Pediatric Post-doctoral training: NewCollege, York, NY, M.D., 1988 Education: Research expertise: expertise: Clinical Professor,Associate Neurology and Pediatrics Susan T. Arnold, M.D. University Nacional Autonoma deMexico, Mexico, M.D., 1985 Vijayanagar Institute of Medical Sciences, Bellary, India, M.B.B.S., 2000 M.B.B.S., India, Bellary, Sciences, of Medical Institute Vijayanagar University, 1985; A.B., MA, Columbia University, Harvard Cambridge, New York, Wesleyan University, CT, Middletown, University Medical 1984; Cornell B.A., Texas Tech University, 1978; Lubbock, B.A., Texas Tech Sciences University Health Gnrlnuooy neurology General Autism, traumatic brain injury, delay, ADHD, brain cognitive Autism, traumatic developmental disorders neurodevelopmental neurobehavior, ethics, Medical epilepsy of management surgical epilepsy, EEG/neurophysiology, Stroke in children, cerebrovascular disease in children, neurologic children, in disease cerebrovascular children, Stroke in Mitochondrial encephalomyopathy, Mitochondrial acidosis stroke-like and lactic for etiologies alternative acute anemia, with children in Neurologic injury syndrome Landau-Kleffner children, dug in treatment Antiepileptic Neurodevelopmental disorders Neurodevelopmental Hospital General de Mexico, Mexico City, deMexico, Mexico General Hospital 1985; Intern, dela Hospital Brooklyn Hospital Center, Hospital Brooklyn 2002-2003; NY, Pediatrics, Intern, Lubbock General Hospital, TexasLubbock General Tech University School of Medicine, Yale-New Haven Hospital, New Haven, CT, 1988- Resident, Pediatrics, UT Southwestern/Children’s, Resident, Pediatrics, 1995-1997; Southwestern/Children’s,UT Resident, Pediatrics, UT Neurology 155 Washington University School of Medicine, St. Louis Children’s Medicine, of School St. Louis University Washington Children’s Specialty The Hospital, Amman,Rotating1995-1996; Jordan, Intern,
UT Southwestern/Children’s, Resident, Child Neurology, 2000-2002; Child Resident, Neurology, UT Southwestern/Children’s, Syria, Hospital, Damascus Pediatrics, Resident, Children’s University State University of New York Upstate Medical Center, Syracuse, Medical Upstate Center, York New of University State Brain metabolism, functional-brain imaging, neural excitability: synaptic diet and medical ketogenic refractory of education epilepsy, Treatment Antiepileptic drug treatment in children Drug clinical research Epilepsy-intractable Epilepsy-intractable, ketogenic diet ketogenic Epilepsy-intractable, Rare and complex diseases, Rare and complex mitochondrial diseases, neurogenetic Headaches, epilepsy, neurodegenerative disease neurodegenerative Headaches, epilepsy, EEG/neurophysiology, epilepsy-intractable, genetic epilepsy syndromes EEG/neurophysiology, epilepsy-intractable, genetic epilepsysyndromes University de Granada, University Granada, College Medicine, of Spain, 1990; Baylor M.D., Amman, Jordan, of University 1995 M.D., Sind Medical Sind Karachi, of College, University Karachi, Pakistan, 1994 M.D., Medicine, of Syria, 1988 School Damascus M.D., University, Aga Khan Medical University College, Karachi, Pakistan, 1997 M.D., Hospital, Resident, Pediatrics, 1998-1999; Columbia University Medical Center, The The Medical University Columbia Center, Pediatrics,Hospital, Resident, 1998-1999; 1999-2000; Pediatric Resident, Neurology, Resident, NY, Neurological Institute York, New of 2000-2002; and for Physicians Surgeons, Center College of Neurology, University Columbia Postdoctoral Research, 1995-1998 Fellow, NY, Molecular Recognition, York, New expertise:Research Child Resident, MA, England Pediatrics,New Boston, Resident, Medical 1996-1999; Center, 2002-2004 Epilepsy, MA, Hospital Boston, Fellow, Children’s 1999-2002; Neurology, Rana R.Rana M.D. Said, Pediatrics and Neurology Assistant Professor, Clinical expertise: transmission Education: 1995 TX, Ph.D., Houston, training:Post-doctoral Education: training:Post-doctoral disorders, neurometabolic diseases neurometabolic disorders, expertise:Research Assistant Professor, Neurology, Physiology and Pediatrics Physiology Neurology, Assistant Professor, Clinical expertise: Juan M. Pascual, M.D.,Juan M. Ph.D. Pascual, Research expertise:Research Fares Kokash, M.D. Kokash, Fares Pediatrics and Neurology Assistant Professor, Clinical expertise: Education: training:Post-doctoral Medicine, of School Knoxville,Tennessee of Pediatrics,University Resident, 2002-2004; UT 2004-2005; Child Resident, Neurology, UTSouthwestern/Children’s, Southwestern, Fellow, Clinical Neurophysiology, 2005-2006 Education: training:Post-doctoral El University, Tech 1999-2000; Texas Child Neurology, UT Fellow, Southwestern, 1988-1991; Pediatrics, Resident, Paso, 2000-2002; 2002-2003 Child Neurology, UT Fellow, Southwestern, 2007 and Saadat A. M.D. Saadat Khan, Pediatrics and Neurology Assistant Professor, Clinicalexpertise: expertise:Research Muna Q. Khan, M.D. Khan, Q. Muna Pediatrics and Neurology Assistant Professor, Clinical expertise: Research expertise:Research Education: training:Post-doctoral Intern, Pediatrics, 2002-2003; UT 2003-2005; Child Southwestern, UT Resident, Neurology, Pediatrics,Resident, UT 2005-2007; Southwestern/Children’s, Child Southwestern, Resident, Clinical 2008-2009 Fellow, 2007-2008; Neurophysiology, Neurology, 156 Neurology Adrian Lacy, M.D.,ClinicalNeurophysiology 1st Year Naseeruddin Khan,M.D., ClinicalNeurophysiology Sailaja Golla,M.D.,Neurodevelopmental Disabilities Cristian Ionita,M.D.,Neuromuscular Medicine Completed 2010 Fellows Jorge Munoz,M.D. M.D. Asra Akbar, 1st Year Lina Shah,M.D. Saima Kayani,M.D. Allen DeSena,M.D. 2nd Year Cherie Herren,M.D.(ChiefResident) Diana Castro,M.D. M.D. Mazen Almidani, 3rd Year Residents Residents, Fellows, Volunteer Faculty andClinical/ResearchStaff 2010 ScholarshipRecipient, American EpilepsySociety Annual Meeting,San Antonio, TX, December2010 Bronx, NY, Fellow, Clinical Neurophysiology, 2007-2008 Neurophysiology, NY, Clinical Fellow, Bronx, of College Medicine/MontefioreCenter, Einstein Neurology, 2004-2007;Albert Medical University/New Cornell York 2002-2004; Hospital, NY,Pediatrics, Fellow, Presbyterian Child Children’s Center,1999-2000; Medical of Hospital Israel New Resident, Jersey at Beth Newark Intern, 1997-1998;Rotating Vellore, College, Medical Registrar, Pediatric India, Christian Post-doctoral training: Education: Research expertise: expertise: Clinical Professor,Assistant Neurology and Pediatrics Deepa Sirsi, M.D. Neurology, 1985-1988 Neurology, Residency,College, 1982-1985; Pediatrics, Baylor Houston, of College Fellow, Medicine, TX, Internship, 1980-1981; University Tulsa Oklahoma Medical Mexico, Senior Rotating UniversidadSocial), Guadalajara, Autonoma deGuadalajara, Internship, 1979-1980; Mexico, Junior Rotating (Servicio Leano Angel Guadalajara, Hospital Post-doctoral training: Mexico, M.D., 1979 de Guadalajara, Education: Research: cerebral palsy expertise: Clinical Professor,Associate Neurology and Pediatrics Zinser,William E. M.D. Regional and general anesthesia study anesthesia general and Regional Bangalore Medical College, India, M.D., India, 1998 College, Medical Bangalore Instituto de Ciencias, A.C., Guadalajara, Mexico, B.S., 1975; Mexico, B.S., University Autonoma Guadalajara, A.C., deCiencias, Instituto
Medical ethics, neonatal neurology, neonatal spasticity, neurodevelopment, ethics, Medical and EEG, epilepsy Antiepileptic drug treatment in children in treatment drug Antiepileptic Hospital Sta. Maria Chapalita, Universidad Autonoma Chapalita, Maria deGuadalajara, Sta. Hospital Victoria & Bowring Lady Curzon Hospitals, Bangalore, India, India, Bangalore, Hospitals, Curzon Lady Victoria &Bowring Neurology 157 Administrator MPH, Program Elizabeth Chapman, RRT, - Epilepsy Eric Dominguez, Practice Manager Case Manager Elia Esquivel, RN, B.S.N., Neuromuscular LD, Dietitian Mary Susan Spears, RD, CSP, (Neuromuscular & Ketogenic Diets) (Epilepsy) Worker Stacy Roush, Social Access Representative Crystal DeLuna, Patient Access Representative Patient Patty Gonzales, Sr. Christina Gonzalez, Scheduler Assistant Administrative Jacquie Haney, Access Services Linda Hernandez, Language Assistant Hopkins, Medical Temika Access Representative Patient Karen Horn, Sr. - Epilepsy Assistant Administrative Liza Lopez, Assistant Sandra Lopez, Medical Assistant Sandra Lovo, Medical Access Representative Patient Michell Pernell, Sr. Amelia Robledo, New Patient Scheduler Assistant Medical Kari Wood, Access Representative Patient Yanez, Ammy Clinical and Support Staff Academic Support Associate Administrative Sandy Pacholick, Assistant Administrative Sr. Lisa Berry, Assistant Administrative Alicia Ponce, Sr. Assistant Education C-TAGME, Kellie Shaw,
Research Coordinators Andersen, M.A., CCRP Mariam Medrith Greene, RN, B.S.N. Coordinator Psychometrician Coordinator Ann Morris, Ph.D. Mary
Pediatric Nurse Practitioners/Physician Assistants Practitioners/Physician Nurse Pediatric RN, CPNP-PC Juanita Dale, Ph.D., PA-C M.P.A.S., Heather Gilbreath, Melanie Gleich, FNP APN, PNP-BC Hildebrandt, RN, M.S., Evelyn Mendoza, PA Diana Sue Polachek, RN, PNP Clinical Nurses Clinical Brill, RN Amanda RN Crystal Carpio, RN Keely Dagley, &KULVWLQH*ULIÀWK51 Jennifer Hogg, RN RN Chloe Miller, McAfee, RN Jackie -HQQLIHU0XUGRFN51 Stephanie Montalvo, RN Rivera, RN Jessica Clinical Staff and Research 158 Neurology t t t t studies: research funded nine in participated Dr. Pascual M. Juan disorders. of seizure avariety population with apediatric in Levetiracetam dose high of safety and efficacy of Investigator the study of aretrospective Principal as serves Dr. Said Rana Dr. Arnold. with along studies Co-Investigators two as on the serve Said Rana and Lennox-Gastaut Khan Saadat Syndrome. Drs. patients with in PI of Clobazam as for study the serving as well as seizures partial refractory patientswith in therapy adjunctive as early in patients givenenrolling of safety Perampanel and efficacy the Investigator to of evaluate astudy Principal as Dr. serves Arnold began Susan study This reliability. and validity its test as multicenter study.well international this as in enrollment in leads Southwestern UT and 2006, deficit neurologic acute of severity the and quantify describe will that NIHSS the of modification apediatric gaps by evaluating these address will study neurological final and initial United of the ameasure the as States in study acute stroke is employed current every nearly in deficit. for outcome. stroke proven Consequently, validity has predictive reliability, has interrater and and NIHSS intra- the However, of stroke-relatedmeasure (NIHSS) isa quantitative Scale that Stroke neurologicNIH deficit The for children. scale children stroke clinical outcomethehinderedthat lack been determine of avalidated by has factors defining in Progress were expressly excluded outcome. determine factors that the regarding cohort studies existing from available fromwith prior stroke of treatment children regarding validation Uncertainty anemia. cell sickle with for children blood transfusion than other stroke, derives studies from no are proven there stroke, for acute accepted management orchildhood strategies widely or prevention of childhood the lackof of impact public of health the Despite magnitude lives. adult the the their throughout and childhood of duration their the of NIHSS. clinical when consid magnified is problems these of This significance health trials stroke. The public childhood of percent60 40 to of survivors of affect attainment academic and life of daily strokeactivities interventions with interferethat Long-term deficits motor cognitive and childhood. top in 10 the among of death causes ranks and America, and in Europe North ageunder year every 18 children approximately per 3.3 Stroke affects 100,000 in children, Children.” in “Validation Stroke Scale Site as NIH Dr. Co-investigator of for the called serves astudy Dowling Michael as well as the limited neuropathies). progressive peripheral (CMT) for Charcot-Marie (hereditary Center the of grant Disease Excellence data There is cure and failure. nofor cardiac DMD/ BMD. Dr.the thedirector site Charcot-Marie respiratory for is Iannaccone eventual Tooth and dependency, wheelchair ambulation, of deterioration to leads that weakness muscle proximal progressive develop DMD/BMD with Boys disease. muscle dystrophic the of form milder phenotypically a dystrophy (BMD) Becker young boys. muscular X-linked is genetic disorder affecting life-threatening and disabling dystrophy. a DMD is muscular nonsense-mutation-mediated Becker and Duchenne with of PTC124 subjects in 2010. in Study journals reviewed Safety Dr. Investigatorand Site for isthe Iannaccone Principal Efficacy aPhase II peer- in published 13 and articles meetings work international present and of at their national many results Faculty 2010. in exceeded $400,000 NIH, of the sources, including from avariety funding Research autism spectrum. the in studies clinical and stroke pediatric in trials clinical trials, drug anti-epileptic trials, clinical disease disorderssystem, neuromuscular the areas: metabolic nervous fiveof in focused are Current studies trials. clinical including studies, clinical of and research neurologic bench/basic conduct avariety Division faculty Research Activities Principal Investigator). This 11-institution infrastructural grant constitutes the first initiative worldwidefirst the to constitutes grant Investigator).Principal This 11-institutioninfrastructural (NAMDC)” consortium (as diseases Co-Investigator Site and mitochondrial “Developing American aNorth titled of Health Institutes National the from grant Act Recovery Reinvestment and A second American targets. therapeutic identify help become and predictors severity can that of to for disease search cancer brain in metabolic alterations human development of for the study additional methods the the and of of MRI methodology novelexpansion MRI glioblastoma” (as in the representsgrant Co-Investigator). phenotype metabolic and challenge This “Genotype titled Act Recovery Reinvestment and sponsored of American by Health the Institutes National the from A grant developmental and epilepsy delay.causes solegroup genetic the provider for as disorder that care of this and comprehensive genetic and diagnosis clinical Center” (as Investigator). Medical positioned Principal has Childrens Center and our program This Medical Southwestern UT at program (CETT) translation test and education (GD)collaboration, syndrome deficiency type 1 Rare Disorders Office ofof titledtransporter “Glucose National Health, Institutes from the A contract to epilepsy. treat used of action somethe drugs mediates and properties vasodilatory has acomponent CO2, that under changes air of(EEG) breathing activity (as consumptionby electrical oxygen control and cerebral air” Co-Investigator) inspired human of the studying “Modulation titled activity A major of of brain Health National Institutes investigator-initiated from the grant ering that children live with the sequelae of stroke for Neurology 159 The NDD team continues to work team The work diligentlyNDD to continues to serve the community large. team The at Northattends Texas special the needs at children Dallas-based site on Treatment Autistic a quarterly on Center basis, with and Carolyn closely works Dr. Garver outstanding and her team specialists. of Drs. Evans speakand to Morris both continue throughout the metroplex in various educational settings, including the Dallas the ISD, Dallas Theological Seminary, other specialtyand programs regarding children with special needs. recruit and characterize range mitochondrial of a broad disease facilitate to patients clinical trialsacross the U.S. and Canada aimed still treat these to but frequent incurable disorders. InstitutesA National Health of / UT Medical Southwestern grant pilot Center titled “Diagnosticsignatures of PI and Co-Investigator Award Recipient metabolic diseasesof (as NMR Pilot high-field spectroscopy” by non-invasive skeletal a muscle MRI develop (leg) spectroscopy, helped Thistheproject institutional award). methodologyinstitutions that most that available is at perform MRIs. studies These will us help understand mechanisms energy of failure the and diagnosis in brainmuscle several of disorders, improve disorders metabolic clinical for and identify trials. indicators) (disease potential biomarkers A National Institutes Health of traininggrant titled in “Epilepsy primary cerebral to energy Sponsor failure” (as researchplan goal to is of proposed The understand, the postdoctoral trainee). quantitatively as fellow a Ph.D. brain of as the possible, excitability dependence brain on energy metabolism studying by both the normal and a prototypic disease state. grant study to Foundation “Childhood devoted A Billingsley brain metabolism: function Fund/ Dallas Women’s This gift on Principal support wasresearch establishedchildhoodto epilepsies Investigator). (as relationships” that arise use deficits. from cerebral glucose (fuel) An titled International Postdoctoral Fellowship European “Studies Union Brain of Metabolism in Epilepsy” (as awarded was on based Thisfellowship of merits the competitive Recipient). Postdoctoral Fellowship to Mentor salary, support proposal to and research project fringethe applicant, mentor and small expenses a current of willpostdoctoral who fellow two spend years with us in the U.S. with Institutes MRI”A National Health of grant titled Volume Spinal Blood of “Quantitative Cord Assessment in the which will supply study spinal to blood cord. approach a new Co-Investigator) develop (as From an standpoint, in education theFrom accredited, year the was and program since it created NDD ACGME has trained Sailaja Dr. Golla.Golla Dr. her finished child firstneurologyits fellow, trainingshe at where Southwestern, also UT served and as in recently published chief Journal resident, Clinical of Neuromuscular Disease. brings She a wealth of experience as well as research and solid clinical skills, and, started neurology and of pediatrics as assistant professor in July 2010. DisabilitiesAs third its the Neurodevelopmental concludes Program year UT at the Southwestern, (NDD) program continues to experience significant growth specificallywith regard to clinical opportunities,community clinics NDD outreach. research, are multi-disciplinaryeducation, in structure and areand specifically serveto childrencreated traumatic brainwith injuries delay, and autism, developmental ADHD/LDissues. program The will expand provide to full-time services NDD both to the Dallas and Legacy campuses beginning underway Plans are to now in July 2010. build an NDD-dedicatedthe space at Legacy campus in open to 2011. Neurodevelopmental Disabilities Program Program Disabilities Neurodevelopmental The expertiseThe of faculty the including epilepsymanagement focused severalon is sub-specialties: comprehensive seizure surgery; neuromuscular medicine clinics including myasthenia gravis, Marie Charcot muscular dystrophy, Zero- cardiovascular care muscle; follow-up; disease; intensive neonatal and transitional adolescent care for Tooth neurodevelopment2-3 clinic; rare disorders clinic; and neurodevelopmental disabilities clinicshyperactivity including attention-deficit neurocognitive delay, autism, disorder/learning disabilitiesand traumaticbrain(ADHD/LD) injury. Clinical Activities t t t t t 160 Neurology Neurology rotation residentsNeurology plus Adult rotating from Neurology, or specialties. other Psychiatry C7/Consultthe required Team on students their includes one at least medical PN third-year resident several and procedures; C10/Consult 500 the support staff; than and attending Team include an teams provides Both eight beds. andmore performed beds unit provides six The Epilepsy Monitoring emergency department. the and (NICU) unit (PICU), unit intensive intensive care neonatal pediatric provide care the coverage the 24/7 in for and patient units the C7/Consult the and Epilepsy Monitoring Unit twoincludes teams: Both inpatient service The Team. Neurology oa iis 9,630 1,898 DeepaSirsi, M.D. M.D. Khan, Saadat 7.732 Total Visits M.D. Arnold, Susan PAs /PNPs Providers Attending Patricia Evans, M.D. M.D. Evans, Patricia M.D. Evans, Patricia M.D. Said, Rana M.D., Ph.D. Pascual, Juan M.D. Iannaccone, M.D., Mchael Dowling, Ph.D., Susan M.S.C.S. Zinser William M.D. Aceves, Jose M.D. Iannaccone, Susan M.D. Said, Rana M.D. Cheng, Jonathan Epilepsy M.D. Arnold, Susasn M.D.Autistic Said, Rana Spectrum Disorder M.D. Arnold, Disorder Susan Attention Learning and Legacy Campus: Clinic Neurodevelopment Zero-2-3 Traumatic Injury Brain Clinic Neurology M.D. Arnold, Cell Sickle Susan M.D. Evans, Patricia Zinser, M.D. William Syndrome/Angelman SyndromeRett Clinic M.D., Dowling, Michael P.D., M.S.C.S. DisordersRare Clinic M.D. Iannaccone, Susan Clinic Continuity Neurology Pediatric Clinic Gravis Myasthenia Patricia Evans, M.D. Clinic Muscle Ketogenic Diet Clinic M.D. Evans, Patricia Clinic Headache M.D. Iannaccone, Susan Clinic Surgery Epilepsy Comprehensive Stroke Clinic Pediatric Comprehensive Clinics Epilepsy Development Cognitive Clinic Charcot-Marie Tooth (Center Clinic of Excellence) Plexus Clinic Brachial Autistic Spectrum Disorders Disorders Attention Learning and Adolescent Clinic Dallas Campus: Patient Visits Clinic Directors Neurology 161 ncy Syndrome,” 2nd Symposium on Glucose Transporter Transporter Glucose on Symposium 2nd ncy Syndrome,” Safety Officer, NIH NINDS Ad hoc review, Data and Safety Monitoring Board for 5-U54-AR-050733, Phase I DataSafety and NIH5-U54-AR-050733, for Monitoring review, hoc Safety Ad Officer, Board NINDS transfergene clinical trial using alpha-SG-deficient limb for muscularAAV1 girdle 2D) (Type dystrophy Director theof Carrell-Krusen Symposium Birth on National Center DMD, Defects care and for Expert comprehensive develop Panel to Member, Disease Disabilities, Control for Centers Developmental Medical Advisory reviewer, hoc Committee,Ad Muscular America Association of Dystrophy Executive Council,Member, American Neurologic Association Annual SummerPhysician-in-charge, Camp, Camp Marc, MDA John Cleburne, TX Editorial Board,Member, Journal Pediatric of Rehabilitation Medicine, Journal Clinical of Neuromuscular Disease, Neuromuscular Disorders Director, Epilepsy Program and Neurophysiology Lab, Children’s Advisory Texas of the Professional Board Epilepsy Foundation Chair, for American Epilepsy SocietyMember, Safety Committee Unit Epilepsy Monitoring for Pediatric Program, Stroke Children’s Co-Director, Pediatric Clinic,Medical Stroke Director, Children’s SickleMedical Cell Neurology Director, Clinic, Children’s Ethics, Chair, Pain and PalliativeTopic American Care for Neurology Annual of Academy Meeting American Neurology Group, of Academy Work Child Neurology Topic International Pediatric Conference, Stroke Section Stroke ANA/ASA Moderator/Reviewer, small instructionImplemented group with and MS3 MS4 medical students in the Pediatric Neurology rotation reviewto the social and emotional impact a neurologically-impaired of child in the family. All students the read and submitted Nichols, an Egg, Joe Peter essay describing by 250 medical their Approximately response. play, date, UT to Southwestern 2007-present been involved students have “Discussion of Outcome Measures in Children and Establishing their Reliability/validity,” Teleconference for for Teleconference in Measures Children and Establishing their Outcome Reliability/validity,” of “Discussion MI, Detroit, February 2010 University, State Disease Wayne Network, North American Charcot-Marie-Tooth UT Southwestern, Pediatric Grand (Ethics), Rounds Building“Consensus Robert (with Rare Bash),” for Disorders 2010 September Westin Symposium, Rare“Myasthenia Disorders Gravis: Neuroimmunologic Immunology and Pathology,” Galleria, Dallas, TX, September 2010 Meeting, Coordinator Stroke DFW Dallas, in“Stroke Children”, TX, 2010 September Pediatric advances Neurosurgery“Current in Diagnosis Grand Autism,” and of Rounds, Management UT 2010 September Southwestern, “TheBrain Within Lecture,Honor de Málaga,Universidad Reasonsof the Limit Málaga, Alone,” Spain, June 2010 “Clinical I Deficie Type Transporter Studies Glucose of Deficiency, Louisville,Deficiency, JulyKentucky 2010 Pediatric IdiopathicNeurology “TheSymposium, Childhood Speaker, Invited Children’s Cook Epilepsies,” TX, August Fort Worth, Hospital, 2010 Susan T. Iannaccone, M.D. Susan T. t t t t t t t Arnold, M.D. Susan T. t t t Michael M.S.C.S. M. Dowling, Ph.D., M.D., t t t t t t t Major Administrative or Leadership or Responsibilities Major Administrative Susan T. Iannaccone, M.D. SusanT. t Faculty participate in eight neurology to up teaching as per week well as conferences a series pediatric of teaching conferences neurologic on topics. t t Michael M.S.C.S. M. Dowling, Ph.D., M.D., t M.D. Golla, Sailaja t Juan M. Pascual, Ph.D. M.D., t t Presentations/Teaching Activities Presentations/Teaching Rana Said,Dr. Program withand the residency clerkship, PN Director for the assistance Program of Coordinator leads the teachingKellie Shaw, program and that medical residents educates and inpatient outpatient studentsfor weeks 10 for fellows blocks, Children’s seven for four-week threeneurology There are adult residents rotations. two each in clinic, the three outpatient to UT seven each, two one Internal Southwestern months for Medicine residents three to and year one fellows neuromuscular one medicine for andadult pediatric fellows neurophysiology/epilepsy thaneach. More 200 intervalsneurology two-week clerkship for students rotate outpatient or either inpatient on each year. rotations Rana R. Said, M.D. t 162 Neurology Michael M.Dowling, M.D., Ph.D., M.S.C.S. Jose Aceves, M.D. Susan T. Iannaccone, M.D. Awards and Honors t t t t t t t t t M.D. Said, R. Rana t t t t M.D., Ph.D. Pascual, M. Juan t t t t t t t t Patricia Evans, M.D. Class of 2010for MS3 Excellence inEducation Teaching Award, Core Clerkship, Doris Duke Innovations inClinicalResearch Award UT Southwestern, 2006-2009 Clinical Research Scholar, Department of ClinicalSciences, Teaching Award, Pediatric Neurology Residents Class of 2010for MS3 Excellence inEducation Teaching Award, Core Clerkship, for mentoring Special Award from graduating Pediatric Neurology residents Academy of Neurology of Academy Workgroup, American Examination Skills Member, Clinical (AES)Society Epilepsy Member, American Content Pediatric Committee, Committee Education Member, University of Citation Texas Center Subcommittee, Graduate Medical Medical Southwestern Member, Committee Education University of Center Texas Graduate Medical Medical Southwestern Academy of Neurology Member, American Subcommittee, Graduate Education Director,Associate Children’s Center Medical Director, Ketogenic Diet Program Student Clerkship Medical Neurology Site Director, Pediatric Southwestern UT Director, Program Residency Neurology Child Foundation, Italy, Calipio reviewer: proposal 2010Grant for Control Prevention Disease and Reviewer, Centers Home Developmental Genetics and Reference Defects Disabilities, Center National on Birth Editor,Associate Neuroscience Letters Alzheimer’stheMember,Association Board of Review Scientific Director,Medical Phelan-McDermid /22q13 Deletion Syndrome Clinic Director, XSyndrome Clinic Medical Fragile Director, Delay DisordersMedical Cognitive Clinic Disorders Director, Clinic Medical Autism spectrum Director, Clinic Medical Traumatic Injury Brain Residency Disabilities Neurodevelopmental Director, Academy of Neurology American on Ethics, Chair, Section Member, Neurodevelopmental Task Disabilities Force, Society Neurology Child Pulmonary & Vascular Biology 163 Biology Philip Shaul, M.D. Philip Shaul, Director, Pediatric Pulmonary Vascular & Pediatric Director, of pediatric research divisions nationwide. divisions pediatric research of Pulmonary Biology Vascular & one of but a handful but of one Philip W. Shaul, M.D., Professor, is Director of Pulmonary is Director of and Vascular Professor, Shaul, M.D., Philip W. Biology and holds the LoweFoundation Professorship in Pediatric Critical Care Research at UT Southwestern. He specializes in neonatal-perinatal medicine, and his research interests are focused signaling on molecules in endothelial raftscell caveolae/lipid that influence vascular healthDr. Shauland disease. his B.A.received Hampshire, from Dartmouth New in 1977 College, Hanover, and his medical He degree Cincinnati, from the of University in Ohio, 1981. received residency training in pediatrics at the Children’s Medical Center of Cincinnati, and 1984, to in was Cincinnati, a fellow of University from 1981 andneonatal-perinatal Infants Rhode of Hospital medicine the at Women thejoined He RI 1986. to Providence, 1984 from Island, University, Brown faculty Shaul was the elected to UT Dr. American of in Southwestern 1986. theSociety of Society Clinical for and was he President in Investigation 1999, Pediatric Researchfor in 2005-2006. Faculty
The facultyThe members in PulmonaryVascularPediatric from of the physician-scientists Biology divisions are and Neonatal-Perinatal Medicine Rashmin (Drs. Savani Pediatric and Phil Critical Shaul), Care Medicine Margaret (Drs. Pediatric Infectious Michelle Gill), Pediatric Respiratory Disease MedicineSchwarz (Dr. Fontán), and Julio Pérez Carolyn(Drs. Cannon Williams) and Olatunji and Pediatric Ellen Endocrinology and Grishman); Drs. Chieko (Dr. Mineo and Michi are scientists working basic Umetani, who in partnership with the physician-scientists. The division’s mission is to expandto is our mission basic understandinglung of vascular and The division’s diseases, striving gainto new thatknowledge will ultimately diagnostic, new to lead and therapeutic prophylactic strategies. Within the of context andlung vascular diseases, inflammation to the and responses division and lung focuses vascular on development and injury. The Division of of Pulmonary Division VascularThe pediatricprogrammaticfor a provides faculty Biology researchhome and and trainees pursuing basic research in Pulmonary Biology and Vascular Biology. is It an exclusively research- driven division in the Department that amplifies Pediatrics, concept of representing thereby a novel effortsthe and effectiveness pediatricof faculty and trainees alike. addition, In PulmonaryVascular a provided Biology has and valuable resource for campus-wide investigative endeavors. This isrepresented by active collaborations between Pulmonary and faculty Biology Vascular and other UT faculty Southwestern in the Departments Internal of Medicine, Cell Biology, Physiology, Pharmacology and Biophysics, and by the participation of Pulmonary and Vascular Biology faculty training in numerous grants and center across the campus. Recently a shared effortby Pulmonary and support to Health of Institutes andVascular Biology the Pulmonary Division of National the and Critical from Care in Medicine the (PCCM) Department grant Internal of training T32 coveted a of procurement in resulted Medicine postdoctoral research trainingat UT Southwestern in Lung Biology and Disease. Pulmonary a handful but of andone research divisions of in Vascular Pediatric departments nationwide. Biology is 164 Pulmonary & Vascular Biology Pulmonary Biology, 1989-1991 Biology, Pulmonary 1984-1987; Children’s Center, Medical Cincinnati OH, Fellow, Neonatology, 1987-1989; Fellow, Post-doctoral training: School, M.B.Ch.B., Sheffield U.K., England, Medical 1982 Education: injury tissue in role of injury,hyaluronan lung surfactant, inflammation, chronic disease, lung expertise: Clinical/research Pediatrics in Chair Buchanan William Vascular and Biology Director,Associate Pulmonary Medicine Neonatal-Perinatal of Division Director, and Professor Savani, M.B.Ch.B. C. Rashmin 1999 Post-doctoral training: Education: Research expertise: Professor Assistant Chieko Mineo, Ph.D. Endocrinology, 2003-2006 Fellow, Southwestern, UT Pediatric 2000-2003; Hospital, OH, Resident, Pediatrics, Post-doctoral training: Sciences, 2008-2011 Scholar, Research Clinical Southwestern, Clinical UT M.D., 2000; NE, Omaha, of Medicine, Education: Research expertise: expertise: Clinical Professor Assistant Grishman,Ellen K. M.D. Fellow, 1999-2003 Diseases, Infectious Pediatric 1995-1998;Resident, Pediatrics, 1998-1999; Resident, Chief Pediatrics, Southwestern, UT Post-doctoral training: Center, M.D., 1995 Center,State University Ph.D., Medical Shreveport, State University 1993; Medical Louisiana Education: expertise: Clinical/research Professor,Assistant Disease Pediatric Infectious Gill, Ph.D.,Michelle A. M.D. &Women’sBrigham Fellow, Research Hospital, Boston, MA, 1998-1999 1993-1996; Fellow, School/ Medical Pulmonology, 1996-1999; Laboratory, Harvard Channing Post-doctoral training: Houston, Sciences, School of Ph.D., Biomedical 1993 Worcester, Institute, Polytechnic 1985; Houston, M.S., UT M.D., MA, 1993; Graduate UT Education: developmentthe of infections novel these to treat therapies CFand of lungs patients with the in infection Pathogenesis of pulmonary expertise: Research expertise: Clinical Professor,Assistant Medicine Respiratory Pediatric Cannon, Ph.D.Carolyn M.D., L. King Edward VII School,U.K., Sheffield, England, VII Edward 1977; A-Levels, King Universityof University of Tokyo, 1982; 1984; Ph.D., B.S., Japan, M.S., 1992 Washington University, MO, 1996; Creighton B.A., Louis, St. University School State University, Louisiana laude, 1988; cum Baton Louisiana Rouge, summa B.S., Texas University, A&M laude, 1982; cum Station, Worcester B.S., College Pediatric endocrinology Pediatric pulmonology pediatric Fibrosis, Cystic asthma, Vascular atherosclerosis biology and Type in Type 1and Gene expression leukocytes 2diabetes in Duke University Medical Center, Durham, NC, Resident, Pediatrics, Center, Resident, NC, Pediatrics, University Medical Durham, Duke UT Southwestern, Post-doctoral UT Fellow, Research Biology, Cell 1994- Babies Children’s and University of Hospitals Cleveland/Rainbow Rock, and Intern Little Sciences, for Medical University of Arkansas Children’s Hospital, Boston, MA, Intern and Resident, Pediatrics, Children’s Resident, and Pediatrics, Intern Hospital, Boston, MA, Neonatal-perinatal medicine, bronchopulmonary dysplasia, dysplasia, bronchopulmonary medicine, Neonatal-perinatal General infectious diseases, immunity, RSV diseases, infectious General Pulmonary & Vascular Biology 165 Children’s Hospital, Columbus, OH, Intern Columbus, Hospital, Pediatrics, and OH, Resident, Children’s Oklahoma University Medical Center, The Children’s Hospital, Oklahoma Children’s The Medical University Center, University of Tokyo, Japan, Postdoctoral Research Fellow, 2001-2002; 2001-2002; Japan, Postdoctoral Research Fellow, Tokyo, of University Universidad Autonoma de Barcelona, Resident, Pediatrics, 1978-1981; Pediatrics, de Barcelona, Resident, 1978-1981; Autonoma Universidad Lung development, lung injury Lung development, Oxysterols, nuclear receptor biology, vascular disease biology, Oxysterols, receptor nuclear Pulmonary and vascularization, morphogenesis endothelial-monocyte Airway smooth muscle, autonomic nervous Airway system, neurogenic autonomic smooth muscle, Respiratory diseases, pulmonary hypertension, lung mechanics Pediatric critical care Pediatric cardiac critical care University of Missouri, of Missouri of University Kansas University B.A., Six-year 1986; City, Colegio Marista De Santiago Santa De University Maria, Spain, B.S., 1971; UNT, B.A., 1994; UT B.A., Medical 1994; 1999 UNT, Galveston, Branch at M.D., University of Tokyo, Japan, B.S., 1991; M.S., 1993; Ph.D., 2000 Ph.D., M.S., 1993; Japan, B.S., 1991; Tokyo, of University Ashfar (PICU) Resheidat, M.D. Cristina (Hematology-Oncology) M.D. Tarango, Rodica Catrinel Marinescu, (Neonatal-Perinatal Medicine) M.D. Katherine Bennett, (Neonatal-Perinatal Medicine) M.D. (PICU) James Reid, M.D. Sarah Oltmann, Resident) (Surgery M.D. (PICU) M.D. Todd, Christopher Fellows 2010 Completed Postdoctoral Fellows, Other Research Trainees and Research Staff and Research Trainees Other Research Fellows, Postdoctoral Education: training:Post-doctoral Pediatrics,Norman, Pediatrics, Resident, Chief Resident, 1999-2002; Baylor 2002-2003; Pediatric Pulmonology, Fellow, Houston, Hospital, Children’s Medicine,College of Texas 2003-2006 Assistant Professor, Pediatric Respiratory Medicine Assistant Professor, Clinical expertise: expertise:Research Olatunji W. Williams, M.D. W. Olatunji Education: training:Post-doctoral Pharmacology 2002-2007 and Research Biochemistry, UT Fellow, Post-doctoral Southwestern, Assistant Professor, Pediatrics and Pharmacology Assistant Professor, expertise:Research 1987-1990; Children’s Hospital of Pittsburgh, Fellow, Pediatric Critical Pittsburgh, of Hospital Fellow, Care, 1990-1993 Children’s 1987-1990; Ph.D. Umetani, Michihisa activating polypeptide II, 5 1 integrin / FN / VEGFR interactions, pancreatic tumor growth Education: Medical 1987 Kansas School, M.D., City, training:Post-doctoral Margaret A. Schwarz, M.D. Associate Professor, Pediatric Critical Care Medicine Clinicalexpertise: Research expertise:Research Julio Pérez Fontán, M.D. Fontán, Pérez Julio Chairman, and Vice Professor Department Pediatrics of Respiratory Division of Interim Medicine Director, Chair B. Steinberg,Joel M.D., in Pediatrics Clinical expertise: Research expertise:Research inflammation Education: 1977 Compostela, Spain, M.D., training:Post-doctoral California of PediatricUniversity Critical San Care Fellow, Francisco, Medicine, 1981-1984; CaliforniaCardiovascular of Fellow, Research San University Institute, Research Francisco, 1982-1985 166 Pulmonary & Vascular Biology t t t Ph.D. Mineo, Chieko t M.D. Grishman, Ellen t t Ph.D, Gill, Michelle A. M.D. t t Cannon-McCullough, M.D., L. Ph.D.Carolyn t t t t t t M.D. W. Shaul, Philip Faculty Research Interests Umetani. Michihisa and laboratories Chieko Mineo Shaul, of Philip Drs. the in are primarily pursued biology of vascular The Pérez-Fontán, studies Julio Cannon. Gill, Michelle Caroline and Olatunji Williams, Schwarz, Margaret Savani, laboratories by the of Rashmin Drs. primarily pursued biology are approaches. prophylactic of therapeutic lung The of and studies end developing goal the new diagnostic, with diseases vascular and lung understand fully strivesdivision to the more efforts, injury.these and Through to inflammation development and vascular and are onlung andfocused Biology responses Pulmonary Vascular The of efforts research Research Activities Associate Senior Research M.S., Yuhanna, S. Ivan Ph.D., Xu, Associate Senior Research Haiming II Assistant Research B.S., Umetani, Junko Frost, M.D. Med.) Natalie (Neonatal-Perinatal Thornton,Janet Associate Senior Research B.S., TechnicianJason Research Mitchell, II Jie Liao, Ph.D., Associate Senior Research Ph.D., Associate Legan, Senior Research Susan Technician Research B.A., I Han, Kevin I Assistant Research B.S., Han, Daniel 2ndYear Dong, Ph.D., Associate Caroline Research Cheong,Naeun Ph.D., Scientist Senior Research Ph.D.,Ken Chambliss, Scientist Senior Research Associate Research Bajwa, M.S., Gagan Ph.D. Jose Barrera, Associate Senior Research M.S., Alsaadi, Rajiha Technician Research B.S., II Mohamed Ahmed, Associate Research M.S., Aditham, Anupama Research Staff 1st 3rd Year 5th Year Keiji Ph.D. Tanigaki, 6th Year Year Lane Lanier, M.D. (PICU) Lane Persad, M.D. (PICU) Elizabeth (Grad. Student) Ulrich Victoria M.D. (PICU) Mahan, Anne Ph.D. Shah, Parth M.D., Sundgren, Ph.D. Med.)Nathan (Neonatal-Perinatal Saddar, Ph.D.Sonika Afandor, M.D.Maria Med.) (Neonatal-Perinatal Wu,Qian Ph.D. The role of eNOS antagonism in the antiphospholipidtheThe role in antagonism of eNOSsyndrome function cell C-reactive which by protein endothelial Themodulates mechanisms function lipoproteins cell density high endothelial modulate by which The mechanisms Type immunology 1diabetes infection the pathogenesisRSV in of The role cells dendritic of infections viral immune Theresponse to host respiratory mucosal fibrosis cystic in infections Novel for therapies pulmonary fibrosis cystic in infections Pathogenesis of pulmonary antiphospholid of the basis syndrome Molecular developing of the lung diseases biology and developmental in pulmonary Role oxide synthases of nitric by CRP development, disease and health vascular and phenotype cell of endothelial Regulation by HDL development, disease and health vascular and phenotype cell of endothelial Regulation biology Role on of estrogen vascular of impact 27-hydroxycholesterol the modifying in by estrogen development, disease and health vascular and phenotype cell of endothelial Regulation Jenitha Jeyaraj, M.D. Med.) Jeyaraj, (Neonatal-Perinatal Jenitha (Graduate Pyle David Student) Wan-Ru Ph.D. Lee, Pulmonary & Vascular Biology 167 Structure-function characterization of SR-BI and PDZK1; Dr. PhilipStructure-function Shaul, Mentor Dr. and characterization PDZK1; SR-BI of Metabolic, toxicology and efficacy studiesof potentialthe medicinalDr. of uses therapeutics;silver-based Mentor Cannon, Carolyn gamma Fc of RIRole in and CRP Src actions in the vasculature; Drs. Philip Shaul and Mineo, Chieko Mentors Impact Philip CRP of angiogenesis; Shaul, on Dr. Mentor Role of α5ß1 integrin epithelial α5ß1 Margaret on of cell; Schwarz,Role Dr. Mentor RHAMM receptor Hyaluronan (HA) in and VEGF-stimulated role its endothelial cell migration and Rashmin Dr. Savani, Mentor angiogenesis; estrogen receptor action nongenomic of Role in breast Philip cancer Dr. Shaul, progression; Mentor Margaret integrin Schwarz,, Dr. α5ß1 Mentor in of lung fibrosis; Role Role of Ephs and Ephs Ephrins of Role in lung vascular Margaret Schwarz, Dr. and parenchymal Mentor development; Philip and dysplasia; Shaul, bronchopulmonary Mentor Dr. beta in estrogen of lung receptor development Role Role of Ephrin B2 on lung morphogenesis; Dr. Margaret Schwarz, Dr. Mentor Ephrin lung morphogenesis; of on B2 Role metabolicon and vascular health;27-hydroxycholesterol, Drs. SERM, Impact the of firstidentifiedendogenous Philip Shaul and Michihisa Umetani, Mentors Pulmonary vascular mechanics lung disease, development, lung TGF-beta mediated regulation of pulmonary vascular development Vascular contribution to BPD Vascular mediation of alveolar differentiation EMAPFloxed mice that can II EMAP KO selectively KO II in different cell types Identify the mechanism pulmonary EMAP induced of II’s fibrosis and region determine the factors thatMap promoter regulate transcription Determine the mechanism which Ephrin by pulmonary induces B2 fibrosis Identify the intracellular Ephrin of region that B2 regulates fibronectinleads deposition to fibrosis that Regulation metabolites function estrogen receptor of cholesterol by and diseases metabolic oxysterols in of atherosclerosis Role Neural contribution to lung injury lung the in neurokinins of Biology lungusing of to in transgenic response receptors its HA injury, role the and mice, The in and knockout particular CD44 and RHAMM the of Investigation molecular signals arising from oxidative and nitrative stresses after injury that initiate the inflammatory cascade, including effectsthe post-translationalof modification on inflammation and surfactant afterlung expression gene injuryprotein Examination the of cellular and molecular signals regulating angiogenesis and alveolar formation Studying endothelial cell in behavior vitro and animal decreased models of alveolar (hypoxia septation and determine to hormonal regulation the alveogensis) regulation of this of intricate process regulation signalingThe of mechanisms by mediated receptors itswithin HA and microdomains and lipid that regulatecaveolae endothelial macrophage, and vascular cell migration smooth-muscle t t Ph.D. M.D., Sundgren, Nathan Sonika Saddar, Ph.D. Sonika Saddar, t Parth Shah, Ph.D. James Reid, M.D. t t Elizabeth M.D. Persad, t t Sarah Oltmann, M.D. Anne Mahan, M.D. Mahan, Anne t M.D. Marinescu, Catrinel Rodica t M.D. Frost, Natalie t t M.D. Bennett, Katherine Maria Afanador, M.D. Maria Afanador, t Barrera, Ph.D. Jose Fellow Research Interests Research Fellow Olatunji W. Williams, M.D. W. Olatunji t t Michihisa Umetani, Ph.D. Michihisa Umetani, t t t t t t t t Margaret Schwarz, M.D. Schwarz, Margaret t t Rashmin C. Savani, M.B.Ch.B. t t t t t Julio Pérez-Fontán, M.D. Pérez-Fontán, Julio t 168 Pulmonary & Vascular Biology t Margaret Schwarz, M.D. t t t t C.Savani, M.B.,Ch.B. Rashmin t t t Ph.D., Gill, Michelle M.D. t L.Cannon, M.D.,Carolyn Ph.D. t t t t t t W.Philip Shaul, M.D. meetings. presentations international and make at national and settings various in teaching didactic perform also Vascular Biology and faculty biology Pulmonary research. vascular biology and research pulmonary Ph.D. and students fellows, graduate post-doctoral fellows in subspecialty pediatric residents, clinical train they the laboratory bench. at There occur and faculty Biology Vascular thePulmonary of activities teaching The primary Presentations/Teaching Activities t Wu,Qian Ph.D. t Christopher Todd, M.D. t Tarango, M.D. Cristina t Keiji Tanigaki, Ph.D. Vascular Conference,Canada, Disease Banff, March 2010 “Growth Factor inVascular Circuitry Morphogenesis,” 3rd Annual Neonatal Pulmonary and Childhood Immunity Kyoto, Session, Japan, Month 2010 “RHAMM Knockout Mice are Protected after Bleomycin-induced Lung Injury,” HA 2010 Inflammation and Vanderbilt Pediatric Grand Rounds, Nashville, TN,Month 2010 “Bronchopulmonary New Dysplasia: Insights into Inflammation and Arrestan of Development,”Lung Inflammation,” Vanderbilt Pediatric ResearchConference, Nashville, TN, Month 2010 “Pulmonary Surfactant, Extracellular Matrix &Innate Immunity: Novel Insights into Regulation the of Lecturer, Key West, FL,Month 2010 “Insights into BPD:The Inflammation Superhighway: Tolls,Signals and Pathways,”Elliot Memorial Jerry NIAID Inner City Asthma Consortium Steering Committee Meeting, Chicago, IL,September 2010 “Allergen Interference with Viral-induced Plasmacytoid De Academy Asthma of &Immunology Allergy Meeting, New Orleans, Month LA, 2010(Poster Presentation) “IgE Crosslinking on Human Ce Plasmacytoid Dendritic Annual Meeting, Vancouver, Canada, May 2010(Poster Presentation) Associated of Spectrum Disease “Rhinovirus, with “Common Resistant Drug Pathogens Cystic inthe Fibrosis Consensus Development Program, MD, 2010 Bethesda, October “Biology of Bronchopulmonary (BPD)and Dysplasia Rationale for Inhaled Nitric Oxide Therapy,” NIH September 2010 to Help and not HRT,” UTSouthwestern on Obesity Alliance Nutrition, Series Seminar Metabolism and Obesity, of“Basic Biology Hormone Replacement Therapy (HRT) with Annual Meeting, San Diego, CA,June 2010 “Extranuclear Actions of Estrogen inthe Vascul Symposium, Annual Biology Experimental Meeting, Anaheim,CA,April 2010. “Non-nuclear Estrogen Receptors and aNovel Estrogen Selective Receptor Modulator,” Featured Topic Vanderbilt Children’s Hospital, Nashville, TN,April 2010 “Vascular of Biology HDL the Receptor SR-BI and its Adaptor Protein PDZK1,” Department of Medicine, Act Locally,” The StraussLecture, Vanderbilt Children’s Hospital, Nashville, TN, April 2010 “Manipulating Molecular Events inEndothelial Cave Cell of Gßγ; protein-protein basis and Gα Molecular ERαand Dr. Mentor between Shaul, interactions Philip Mentor Dr. Schwarz, mechanisms; Margaret α5ß1/αVß3 adhesion through II) role mediating in (EMAP II polypeptide activating Endothelial-monocyte Chieko Mentors Mineo, and pathogenesis antiphospholipidRole of Shaul the members the of in Philip Drs. LDL receptor syndrome; family Mentors ChiekoMineo, and Shaul Philip Drs. signaling, of insulin antagonism of basis CRP Molecular Options,” Center for Silver Therapeutics Research, Akron, OH, July 2010 ature,” 92nd Symposium, Science Society Basic Endocrine the Diagnosisofthe Rhinovirus,” Pediatric Academic Societies lls Interferes with CD4Alloproliferation,” American olae to Prevent Cardiovascular Disease: Think Globally, ndritic Cell Function;ndritic Cell Mechanisms of Disease,” NIH/ Patient and Current Inhale Estrogen to Prevent Cardiovascular How Disease: d Antimicrobial Treatment Pulmonary & Vascular Biology 169 Vice Chairman, Department of Pediatrics, UT Southwestern Pediatrics, of Department Chairman, Vice Children’s Affairs, Medical for President Vice Executive Southwestern UT Services Development, Program Pediatric and Dean for Associate UT Southwestern Medicine, Respiratory Pediatric of Division Director, Interim Program Grant CTSA Pilot Chairman, Radiology of Chair Committee Search Co-Chair, Grant T32 Training Director, Associate Directors Board of Children for Anesthesiologist Chairman, Member, Pediatric Endocrinology Scholarship Oversight Committee Endocrinology Oversight Scholarship Pediatric Member, Course Director, Pediatric Infectious Diseases Series Curriculum Infectious Core Pediatric Course Director, Society Disease the 2010 Pediatric Infectious for of in the Area t Submissions Abstrac Research SPR Reviewer for Meetings for Severe Therapy Omalizumab (Preventative PROSE Consortium Asthma City Inner NIH/NIAID Member, Team Protocol Clinical Trial Exacerbations) Fall Committee Student Program Graduate Immunology Member, Committee Presentations and Publications Consortium Asthma City Inner NIH/NIAID Member, Committee Development Studies Mechanistic PROSE Consortium Asthma City Inner NIH/NIAID Member, Member, American Thoracic Society (ATS) Pediatric Assembly Assembly Pediatric Thoracic Society American (ATS) Member, Committee Program Program Screening Newborn Texas Stakeholder, Fibrosis Cystic Corp., Commercialization Research Akron Officer, Chief Scientific Inc. Nebusil, DBA Children’s Medicine, Respiratory of Division Director, Associate Dallas Center, Medical Center, Development Therapeutics Fibrosis Cystic Director, Dallas Center, Medical Children’s Children’s Program, Pulmonary Fellowship Pediatric Director, Dallas Center, Medical Medical Children’s Committee, Improvement Process Member, Dallas Center, Committee, Advisory Clinical Research Children’s Member, Dallas Center, Medical Children’s Dallas Center, Medical UT Southwestern Committee, Interview Core Member, Director, Division of Pulmonary and Vascular Biology, UT Southwestern Biology, Vascular Pulmonary and of Division Director, School, UT Medical UT Southwestern Program, Training Scientist Medical Committee, Steering Member, Sciences Biomedical School of Graduate Southwestern Series, Lecture UT University Committee, Steering Member, Southwestern Biology in Lung Program NIH T32 Training Director, Co-Program Diseaseand Medicine Institute Medical Hughes Howard Director, Co-Program Program Graduate into Development Career Research Child Health Director, Training (K12) Award “LXRbeta Promotes Vascular Reendothelialization Via a Novel Mechanism Involving Non-nuclear Signaling in Signaling Non-nuclear Involving Mechanism a Novel Via Reendothelialization Vascular Promotes “LXRbeta 2010 March CO, Keystone, Symposium, Keystone Endothelium,” Disease,” and Health SERM, in Cardiovascular Endogenous Identified the First 27-hydroxycholesterol, of “Role 2010 August CO, Snowmass, Conference, Research Summer FASEB LSBM Tokyo of Dysfunction, University Metabolic and in Cardiovascular 27-hydroxycholesterol of “Role December 2010 Japan, Seminar Series, Tokyo, t t t t t t t t Ellen M.D. Grishman, t M.D. Fontán, Pérez Julio t t t t t Michelle Gill, Ph.D., M.D. Michelle Gill, Ph.D., t Carolyn L. Cannon, M.D., Ph.D. Carolyn M.D., L. Cannon, t t t t t t t t t Philip W. Shaul, M.D. Shaul, Philip W. t t t t t t Major Administrative or Leadership Responsibilities Major Administrative t t Michihisa Umetani, Ph.D. Michihisa Umetani, t 170 Pulmonary & Vascular Biology t Ch.B. M.B., Savani, C. Rashmin t M.D., Cannon, Ph.D. L. Carolyn t M.D. W. Shaul, Philip Awards andHonors t t t t Olatunji W. Williams, M.D. t t Margaret Schwarz, M.D. t t t t t t t C.Savani, M.B.,Ch.B. Rashmin March of Dimes (Texas) ofMarch Dimes Physician Award Excellence Perinatal Officer, Scientific Chief NorTech InnovationAward WileyInc. CEO to Nebusil, PhD Youngs, of Honor, Center, Children’sHall of Medicine College Medical Hospital Cincinnati University of Cincinnati Member,Consortium The of Children’s CampsAsthma Counselor, Camp Broncho of North Texas Pediatric Site Consultant, Hereditary Telangiectasia Center Medical Director, Function Pulmonary Laboratory, Children’s Member, Integrative Graduate Biology Program Exam Qualifying Committee of Christopher Javadi Member, NHLBIRespiratory Integrative and Biology Translational Research Study Section Associate Editor, Vascular Cell Member, Consulting Editorial Board, Journal of ClinicalInvestigation Molecular Physiology Member, Editorial Board, Journal of Biological Chemi Neonatal-PerinatalChief of Service, Medicine, Children’s PediatricsChief of and Service, Neonatal-Perinatal Medicine, Parkland Associate Director, Division of and Pulmonary Vascular Biology, UTSouthwestern Director, Division of Neonatal-Perinatal Medicine, UTSouthwestern stry and American Journalstry of Physiology-Lung and Cell Respiratory Medicine 171 Vice President of Medical Affairs at Children’s. The neural contribution to lung lung to contribution neural The Chairman and Vice Professor Pediatrics, the of M.D., holds Fontán, Julio Pérez Children’s. Chair B. Steinberg,Joel M.D. in Pediatrics andat serves as the Interim Director Affairs Respiratoryof UT is also Medicine at He Southwestern. Associate Dean for Medical of Pediatric Services UT at and Southwestern and Executive Program Development President Vice injury neurokininsand of biology in Fontán’s the Pérez lung are the focus Dr. of his medical received Fontán degree Pérez summaresearch. cum Dr. from the laude performed his He residency de Santiago De Compostela, Spain,Universidad in 1977. and a 1981, to from 1978 de Barcelona in Autonoma Pediatrics the at Universidad California of the at University fellowship and the Cardiovascular Research Institute joining to Prior the 1984. to UT faculty, Southwestern in San Francisco 1981 from the of was faculty Fontán a member California Pérez of the at University Dr. in in St. Louis, University and Washington University Missouri.San Yale Francisco, He was honored as the Alumni Endowed Professor of Pediatrics at Washington Pediatrics Washington as of at the Alumni Professor washonored He Endowed Medicine of School inUniversity 2001. Respiratory Medicine Cystic fibrosis (CF), pediatric pulmonology, respiratory pediatricdiseasespulmonology, (CF), Cystic fibrosis Children’s Hospital, Boston, MA, Boston, Hospital, Intern Pediatrics, and Resident, Children’s Medicine Texas A&M University, College Station, B.S., cum laude, 1982; Worcester College B.S., Worcester Station, cum 1982; laude, A&M University, Texas Julio Pérez Fontán, M.D. Fontán, Julio Pérez Interim Director, Pediatric Respiratory Pediatric Director, Interim Carolyn L. Cannon, M.D., Ph.D. L. M.D.,Carolyn Ph.D. Cannon, Assistant Professor Clinical/research expertise: including asthma, interstitial pathogenesis lung disease, lung disease, chronic bronchoscopy, pulmonaryof infection in the with patients novel lungsof of CF and the development treattherapies to these infections including targeted nanoparticles delivery depot provide to of classa new antimicrobials silver-based of Education: UT Graduate 1993; MA, M.D., UT M.S., Houston, 1985; Polytechnic Institute, Worcester, 1993 Biomedical Ph.D., of School Sciences, Houston, training:Post-doctoral Channing Harvard Laboratory, 1996-1999; Pediatric Pulmonology, Medical Fellow, 1993-1996; 1998-1999 MA, Boston, Hospital, Research Fellow, School/Brigham & Women’s Faculty Additional faculty has allowed the existing enhancement of programs. example, the For respiratory inpatient service, serving the in patients the general pulmonary program and the various specialized programs including pulmonarysleep, vascular disease, asthma and cystic Respiratory hasthe expanded fibrosis, substantially. In 2010, Medicine Division began the providing of respiratory separate service coverage of the C-Tower on floor the seventh and the consultative service Children’s at throughout services the campuses, provided inpatient both as at Children’s well as the care neonatal intensive unit Parkland.at Respiratory Medicine continued to grow withPreeti Respiratory grow Sharma to Medicine continued us Dr. faculty the joined a new addition of member. as a board-certified pediatricpulmonologist pediatricher completing after pulmonaryat medicinefellowship the Hospital. Children’s Chicago, Comer of University The Division of Respiratory Medicine provides care for Respiratoryof Medicine provides for Division infantscare The throughwith adolescents a varietyrespiratory of disorders,including and acute lung parenchyma and chronic airway diseases, weakness,ventilatory muscle and the example, breathing. division of chronically For cares a large of cohort control for neurologic of disorders ventilated children, children with pulmonary artery hypertension, children in Created as 2006, well as children in Center. Respiratory Center, served Disorders the the Sleep by multi-bed and Teaching accredited Cystic Fibrosis Care a form associated and healthcare together, physicians numerous who eleven Medicineencompasses professionals truly multidisciplinary campuses. program the at two Children’s 172 Respiratory Medicine Pulmonology, 1992-1995Pulmonology, 1989-1992; Science Center, University of Colorado Health Denver, Fellow, Pediatric Post-doctoral training: 1989 M.D., Station, Education: lung transplant Johnson syndrome/TENs, Steven fibrosisairways, microbiology of cystic asthma, interventions, invasive pulmonary and bronchoscopy hypertension, muscle disorders,pulmonary chronicneonates lung disease, with expertise: Clinical/research Associate ProfessorClinical Steven Copenhaver, C. M.D. Children’s 1972-1973 Resident, Pediatrics, 1970; 1970-1972; Pendleton Camp U.S. Pediatrics, Japan, Sasebo, Navy and Southwestern/ UT Post-doctoral training: Education: expertise: Clinical/research Clinic Fibrosis Cystic Director, Professor Assistant Clinical M.D. Prestidge, B. Claude Pulmonology, 2001-2004; Fellow, Sleep 2004-2005 Medicine, Oncology, 1995-1996; Tulane Center, University Fellow, Medical LA, New Orleans, Pediatric 1992-1995; Center, Sciences Pediatrics, Fellow, Health Brooklyn, Hematology/ SUNY Pediatric Post-doctoral training: Education: pulmonology, pediatric diseases sleep respiratory apnea children, in expertise: Clinical/research Professor Assistant S. Kamal Naqvi, M.D. Fellow, Fellow, Research Pulmonology, 2000-2003; Pediatric 2003-2004 1997-2000; Resident, University, Pediatrics, Piedras, Indiana Rio Medicine, Indianapolis, Post-doctoral training: M.D., Piedras, 1997 Rio Medicine, Education: sleep and medicine function expertise: Clinical/research Professor Assistant Tanya M.D. Martinez-Fernandez, M. 1981-1984,Pulmonology, Physiology, Fellow, 1984-1987 Cellular Columbia University of College Physicians Surgeons, New and York, NY, Fellow, Pediatric Post-doctoral training: M.D., 1978 Lexington, Medicine, Education: medicine care critical and diseases neuromuscular expertise: Clinical/research Professor Peter Luckett, M.D. M. 1996 Center, Science University of Colorado Health Denver, Fellow, Pulmonology, 1993- Pediatric Post-doctoral training: Education: fibrosis cystic asthma, lung disease, expertise: Clinical/research Associate ProfessorClinical Andrew S.Gelfand, M.D. Sterling College, KS, B.S., 1984; Texas B.S., KS, Center, College, Sterling University A&M Medical College UT Southwestern, UT M.D., 1968 1989 M.B.B.S., Pakistan, University College, of Dow Karachi, Medical 1993; B.A., School Universityof University Rico of IL, of Chicago, Puerto B.G.S., 1975; University of Kentucky, University of College of Lexington, Kentucky UT Austin, B.A., 1986; B.A., Baylor Austin, UT of College Houston, Medicine, M.D., TX, 1990 Duke University Health Center, Durham, NC, Resident, Pediatrics, Center, Resident, NC, Pediatrics, University Health Durham, Duke UT Southwestern/Children’s Center, 1968- UT Medical Pediatrics, Intern, Center,NY, The Brookdale Medical University Resident,Brooklyn, School of Rico Hospital, University University of Pediatric Puerto 1978-1981; Resident, Pediatrics, University of Kentucky, Lexington, Baylor Houston, of College 1990-1993; Medicine, Resident, Pediatrics, Chronic mechanical ventilation, premature neonates with chronic chronic with neonates premature ventilation, mechanical Chronic Cystic fibrosis, chronic mechanical ventilation, premature fibrosis, Cystic chronic mechanical Cystic fibrosis Cystic Sleep non-invasive disorders, ventilation, narcolepsy, obstructive pulmonary pulmonology, Pediatric disease/infant lung infant with pulmonology, Pediatric associated disease respiratory Respiratory Medicine
173 Pamela Petersen, RN Clinical Nurse Jennifer RN, Powell, BSN, MHA CF Practice Manager Rachel Rosen, RN, MSN, CPNP Clinical Nurse Practitioner William Ruiz, AE-C RRT, Respiratory Care Practitioner Laura AE-C Smith, RPFT, RRT-NPS, Respiratory Care Practitioner Margaret Smith, RN, BSN CF Clinical Nurse Urbanczyk,Brenda RN, BSN, BBA Practice Administrator Kathleen Dunn-Richmond, RRT CF Respiratory Care Practitioner Christine RN, CPNP Wagner, Clinical Nurse Practitioner Andrew Hebert, RCP BSRC, RRT, CF Research Coordinator Izaguirre,Maria MA Medical Assistant LuAnn CPFT Jackson, RRT, Respiratory Care Practitioner Paul Klemm, RPFT RRT, Respiratory Care Practitioner William RCP Kreul, RRT, Respiratory Care Practitioner Elizabeth Lopez, MA Medical Assistant Robin Luffy, RN, CPNPMSN, Clinical Nurse Practitioner Vivian MA Ojeda, Medical Assistant Poonam RN, Patel, BSN CF Clinical Nurse Respiratory diseases, pulmonary hypertension, asthma acute Chronic respiratory failure, Chronic disease, lung chronic neuromuscular General pediatric asthma, Pulmonology, Cystic Fibrosis Pediatric pulmonology respiratory diseases including premature Oklahoma University Medical Center, The Children’s Hospital, Oklahoma Children’s The Medical University Center, Texas Children’s Hospital/Baylor College of Medicine, Houston, Medicine, College of Houston, Hospital/Baylor Children’s Texas Albert at Hospital Einstein Medicine, College Children’s of University Pediatric Hospital, University of Puerto of Pediatric Rico, University Hospital, Rio University Piedras, UNT, B.A., 1994; UT B.A., Medical 1994; 1999 UNT, Galveston, Branch at M.D., University of Pennsylvania, Philadelphia, B.A., 1986; Temple University School of of School University Pennsylvania, of University Philadelphia, B.A., Temple 1986; Chicago/Pritzker of Chicago, IL, of University University A.B., 1998; with honors, University of Puerto Rico, Humacao, B.S., 1994; Ponce School of Medicine, of Puerto School Puerto of Rico, University Ponce B.S., Humacao, 1994; Clinical/Research Staff Abraham,Suja RN Clinical Nurse Barbara Baum, LMSW CF Social Worker LD RD, CSP, Genelle Beerbower, CF Clinical Dietitian Linda Blane, RN Clinical Nurse RN, BSNAmy Boronow, CF Clinical Nurse Cindy Contreras, MA CF Medical Assistant Ashlee RRT Dillow, Respiratory Care Practitioner Katherine RN, Gapp, MSN, CPNP Clinical Nurse Practitioner Jamie Grollman, Ph.D. CF Clinical Psychologist Olatunji W. Williams, M.D. W. Olatunji Pediatric Respiratory Medicine Assistant Professor, Clinical/research expertise: therapy, lung mechanicstherapy, Education: training:Post-doctoral Pediatrics,Norman, Pediatrics, Resident, Chief Resident, 1999-2002; Baylor 2002-2003; Pediatric Pulmonology, Fellow, Houston, Hospital, Children’s Medicine,College of Texas 2003-2006 Assistant Professor Clinical/research expertise: Preeti Sharma, M.D. disorders, bronchoscopy, asthma, disease, lung restrictive aspiration, sickle chronic cell-related bronchoscopy, disorders, of diseaselung respiratory consequences ventilation, and wall chest non-invasive disorders, neuromuscular of as diseasescoliosis, early well as onset the respiratory complications Education: 1990 M.D., Medicine, Philadelphia, PA, training:Post-doctoral Hospital/Harvard Children’s Boston Medical MA, School, Pediatrics, Resident, 1990-1993; Pediatric 1993-1996 Pulmonology, Fellow, Education: Medicine, of School IL, 2002 M.D., training:Post-doctoral PediatricPediatrics, Resident, Pulmonary Fellow, 2002-2005;Bronx, NY, Montefiore, Pediatric IL, Hospital, Medicine, 2005-2006; Fellow, Children’s Chicago, Comer of University Clinical Chicago, Maclean of for Center University Pulmonary Medical Medicine, 2007-2010; Ethics, Clinical IL, Fellow, Bioethics, 2008-2009 Peter N. Schochet,Peter M.D. Clinical Assistant Professor Clinical/research expertise: neonates with disease, lung neonates chronic interstitial disease, lung asthma, bronchoscopy Education: 1998 Rico, M.D., training:Post-doctoral Harvard Hospital, Children’s Medical MA, Boston, School, Fellow, 1998–2001; Resident, Pediatric Pulmonary Medicine, 2001-2004 Yadira M. Rivera-Sanchez, M.D. M. Rivera-Sanchez, Yadira Assistant Professor Clinical/research expertise: 174 Respiratory Medicine in the last year. last the in BPD. in conferences work international beenpresented has growth Dr. three in Williams promote vascular and alveolar in order and to activation TGF-β thatsignaling regulate molecules and manipulating to defining isdedicated focus research Dr. Williams’ development. lung regulates that factor growth (TGF-β), a factor-beta growth transforming of elevated activation with lungdevelopment associated disrupt processes are oxygen) these also that and can (high (low oxygen) hypoxia suchas hyperoxia It and stresses to addition prematurity, in environmental that is now known treatment. and prevention disease to vital is that understanding an development, lung regulate that mechanisms part from the (BPD)Bronchopulmonary dysplasia in the andin 30 to 50percentresults United States infants of affects premature disruption of normalNeurology, complications respiratory disease. the to study of neuromuscular lung development. Pediatric in Chair Westcottcontinues to Dr. work T. Distinguished with Susan Elizabeth Jimmy the Iannaccone, Dr. Peter consequences respiratory Schochet the investigates of early-onset Dr. scoliosis. Additionally, Dr. Schochet Olatunji Williams acomputer-driven using children protocol. of ill development control glucose critically of in strict includes work trial Recent a clinical care. critical strives pediatric in trials clinical and disease, neuromuscular in outcomes to understandDr. Peter Luckett’s center interests research on acute lung the molecular abrogate pathways, developmentresistance. detoxification the of or, of bacterial toxicity inhibition silver through to may lead to methods studies these from Insights cells. lung and of on silver bacteria impact the studies Cannon group also the detoxification, and toxicity silver understand models.To infection in mouse efficacy have nanoparticles, aureus pathogens CFlung the to including date tested species bacterial all complexes N-heterocyclic silver carbene of of (SCCs), novelseries silver-based antimicrobials, growth the inhibit which including but not limited to obstructive sleep apnea, chronic bronchiectasis with an acute exacerbation, chronic lung an sleep apnea, chronic bronchiectasis with but toincluding obstructive not limited acute asthma exacerbations and status asthmaticus, complicated pneumonias, patients status post airway surgery for process, acute respiratory an hospitalized diseases neuromuscular ventilation patients and with on mechanical chronic failure with respiratory but to patients is limited not consists primarily The patient service populationthis on basis. worker, rounds on aregular in coordinator, nurse participate acare charge aregistered and therapist arespiratory resident. APharm-D, Anesthesia an asocial and anutritionist, interns resident,senior Pediatrics general Pediatrics two physician, Medicine one one are Pulmonary Pediatric Admissions Service Pulmonary to the times at all Assigned aConsult/Bronchoscopy and consists Service. Admissions and of Service now an it created2009 as exists was in Service development the in process of improvement several Dr. beeninstrumental has Inpatient The Rivera Pulmonary initiatives. duties. inpatient Medicine administrative Dr. Pulmonary oversee Pediatric Cannon Dr.the Yadira and Rivera Carolyn Inpatient Service Activities Clinical Pseudomonas aeruginosa of regulator clearance in conductance (CFTR) plays fibrosistransmembrane CF, cystic protein underlying and the gene defective laboratory explores role the the Cannon that the mouse of models and infection, vitro Using in both fibrosis cystic and(CF) of development lungs patients with the found in infections. these of therapiesnoveltreat to species related bacterial several Cannon’s with Dr. infection Carolyn pathogenesis on group the of focuses pulmonary response. inflammatory of the regulation the neuropeptides in of sensory participation the outflowsandtheoverlap bronchomotor between the Recent on been andnetworks. attention has focused breathing phrenic and relationships the vagal control between of breathing through bronchomotor part integral an as system have contributed studies present toof the the view neuroanatomical Physiological and airways. of the function and Dr. in Researchers Pérez Julio Fontán’sthe structure system theon nervous influence of laboratorythe investigate andasthma. fibrosis, development,diseases cystic consequenceslung includes in research of neuromuscular pulmonary member isdevelopinginterest areas of Each faculty for scholarship, have which efforts expanded. research program, an excellent clinical theestablishment of been has the Division Medicine of Respiratory of priority first the Although Research Activities (MRSA) and Bcc organisms. Nebulized SCCs, formulated both as a solution and after incorporationinto asolution formulated as both SCCs, after and Nebulized (MRSA) organisms. Bcc and and Burkholderia cepacia complex (Bcc) organisms. The group also studies the activity of a complexthe activity (Bcc) studies groupalso The organisms. injury, mechanical ventilation, near-fatal asthma, pulmonary pulmonary asthma, near-fatal ventilation, mechanical injury, P. aeruginosa , methicillin-resistant Staphylococcus Staphylococcus Respiratory Medicine 175 p of pulmonaryp of and general pediatrics textbooks has been jointly staff the High Risk Multidisciplinary Asthma Clinic that provides comprehensive evaluation of patients with with Drs. Martinez and Rivera-Sanchezpatients serve asof liaisons between the Respiratory Medicine and the Allergy evaluation Divisions that comprehensive provides that Clinic Asthma Multidisciplinary Risk High the staff jointly Asthma Outpatient Services Pulmonary Aerodigestive DisordersPulmonary Clinic (PAD) Aerodigestive PAD clinic, Rivera-Sanchez staffsmultidisciplinary a of Yadira pulmonary the the Dr. effort component between evaluationof GastroenterologyRespiratory and provides comprehensive Therapy Medicine, Speech that ENT, involvingchildren pulmonary airway, the upper problems with digestive and complex upper tract. Clinics occur on month. of each the firstMonday A pulmonary function laboratory is conveniently located adjacent to the outpatient pulmonary clinicWilliams area. serves as the Olatunji Dr. Medical the pulmonary for Director supervising function and the laboratory, execution respiratory studies. of interpretation has laboratory function The evaluation.the capacity performto comprehensive pulmonary infant diffusing lung volumes, testing spirometry, exhaled only simple Available includes capacity, the oxide,nitric ofevaluation has Dallas Children’s addition, In testing. exercise cardiopulmonary and reactivity airway Texas. North in laboratory function Specialized clinical outpatient activities include: The outpatient clinic staff includes nursing, respiratory therapy, social work and nutrition who are available to supply clinicnutrition whoavailablesupply outpatient are socialto staff workand The nursing, respiratoryincludes therapy, nursing needs. In the addition, and home staffqualified is equipment coordinate education andsupport provide help to use andin asthma respiratory equipment in the management clinic setting. Dr. Tanya Martinez and organization clinics Tanya the of outpatient leads the andDr. also development the Comprehensive oversees Asthma careoutpatient activities The Program Children’s. of at RespiratoryMedicinethe a Division encompass with center the capability evaluating of comprehensive a variety in respiratory disorders a multidisciplinary of approach. The outpatient clinical area is housed on the 5th floor of thein Pavilion Dallas Outpatient with a limitedBuilding number at Children’s of clinics Medical at the Center Children’s throughare provided effort physicians nursepractitioners. between the advanced combined and at Legacy Outpatient Center in Plano. Consultative services Outpatient Services Outpatient The inpatient pulmonary The inpatient serviceremains sub-divided(Admissions and Consults/ into the current components two a pediatric by which is headed each of pulmonary assists practitioner nurse An physician. inpatient Bronchoscopy), the consult pulmonary attending. respiratory A leader therapist participates in daily rounds along with the team of andpulmonary thephysicians charge The nurse. service began incorporating family-centered, a on rounds bedside twice team weekly initiative, communication. As basis a quality improve to the service improvement began tracking streamdays without blood infections. Further, the care afternoon team holds now identifyto “huddles’ patients the with courses that worrisome warrant overnight. monitoring closer incorporated into the inpatient pulmonary the into inpatient incorporated textbooks These rotation. in pulmonary stored are the and floor can be utilized general pediatrics by and anesthesia rotating through residents the pulmonary inpatient service. The Respiratory Medicine Inpatient Service faculty continue to provide a once or twice a week rotating lecture schedule schedule lecture rotating week a twice or once a provide to continue faculty Service Inpatient Medicine Respiratory The a pulmonary a rotating is also asthma by on schedule provided Teaching the practitioner, nurse educator, residents. for speech pathologist and grou respiratory therapist. A core The The Consult Serviceprovides service Dallasto both well entireMedicalas Children’s the as Parkland the Center, RespiratoryHealth One Medicine and physician an system pulmonary NICU. inpatient practitioner nurse are assigned theto Consult Service all are at performed either in the times. Main bronchoscopies Inpatient Operating (OR), Room are assisted the by Bronchoscopies (NICU). Care Unit Neonatal Intensive or (PICU) CarePediatric Unit Intensive Main Respiratory OR department. Therapy disease prematurity of with an respiratory acute illness, interstitial lung disease with anrespiratory acute illness for or pulmonary The pulses agents. other immunosuppressive steroid or service hasdesignated been pilot service the a for programnew named “Revitalizing other Among things Care the at Bedside.” this program will actively incorporate patients and family daily into members rounding activities.This program patient care, wellasto intends improve as satisfaction and patients of their families. 176 Respiratory Medicine t t t t t control-related disorders. of respiratory- sleep- and on avariety services provides which sleep clinical program, the directs Naqvi Dr. Kamal Sleep Disorders Center t t Hemorrhagic Telangiectasia Center here Southwestern. for Hereditary atconsultant UT the pulmonology pediatric the as serving and hypertension pulmonary for patients with caring including disease, vascular pulmonary of patients care with the closely improving involved remained has with Dr. Olatunji Williams Clinic Hypertension Pulmonary on adolescentfocused clinic patients is held Theonce a month.multidisciplinary disease. to neuromuscular involvement secondary pulmonary with management of and children provides evaluation and Department Neurology the with isa joint effort The clinic Diseases. Neuromuscular various of needs unique olderto the teenagers with devoted clinic the PeterAdolescent Drs. isa which Schochet Peter and staff multi-disciplinary Luckett Muscle clinic, neuromuscular disease. of needs for patients respiratory with the on per weekDr. caring focused clinic Peter holds Luckett one pulmonary Clinic Disorders Neuromuscular campus. Dallas on and Tuesday, campus Legacy andthe Thursday Friday at the at Monday on held are Clinics basis. weekly a on clinics in participates fibrosis cystic in interest an with gastroenterologist psychologist. Dr. apediatric Sathe, Meghana clinical and specialist life child nutrition therapist, respiratory specialist, worker, asocial as well as includes nurses, dedicated team Fibrosis accredited by Cystic the Foundation.is fully care The The center Gelfand. Steven Andrew Copenhaver and Cannon, fibrosisincludeMichael Carolyn Brown, Drs. cystic with the children for caring fibrosis in physicians Other North Texas. cystic population for of largest patients the with cares which Teaching and Care Center at Center Children’s Dallas, Medical FibrosisDr. Cystic of the director as Claude Prestidge serves Cystic Fibrosis Care andTeaching Center beenapprovedhas for 2011. expected and Ball Charity Crystal the through for clinic the funding Initial area. Clinic Allergy and Pulmonary shared the seen in at CMC Patients patients. to are provide Management Program ongoing education toasthma our Asthma the with educators asthma closely works includes certified that six The team asthma. threatening life and uncontrolled asthma Five half-day clinics aweek Five clinics half-day for equipmentavailable staff Sleep technology and education support positive airway pressure/non-invasive ventilation titrations equipment and polysomnography, to perform technologies available State art and actigraphy of the multiple sleep test, latency sleeptreat disordered breathing to provide non-invasive follow clinic monthly using Dedicated for up care children positive to pressure therapy Comprehensive center of children sleep for evaluation disorders in the once amonth occur Clinics hypertension of pulmonary suggestive symptoms Comprehensive or with presenting of patients diagnosed evaluation Respiratory Medicine 177 d Antimicrobial Treatment Treatment d Antimicrobial Patient and Current Inhale Current and Patient cialization Corp., DBA Nebusil, Inc. Nebusil, DBA Corp., cialization Medical Director, Pulmonary Function Laboratory, Children’s Laboratory, Pulmonary Function Director, Medical Texas North of Broncho Camp Counselor, Asthma Camps Children’s of The Consortium Member, Medical Director, Sleep Disorders Center, Children’s Center, Disorders Sleep Director, Medical Fellowship Medicine Sleep Director, Site Medicine Sleep of Academy American Fellow, Services Pulmonary Inpatient Director, Medical Plano Hospital, Presbyterian Health Texas Pediatrics, of Chairman Plano Hospital, Presbyterian Health Texas Review Committee, Peer Pediatric Chairman, Plano Hospital, Presbyterian Health Texas Board, Medical Member, Medical Director, Comprehensive Asthma Center, Children’s Center, Asthma Comprehensive Director, Medical Services Pulmonary Outpatient Director, Medical Member, American Thoracic Society (ATS) Pediatric Assembly Program Committee Program Assembly Pediatric Thoracic Society American (ATS) Member, Program Screening Newborn Texas Stakeholder, Fibrosis Cystic Commer Research Akron Officer, Chief Scientific Dallas, Texas Baylor, House, Our Children’s Director, Medical Children’s Department, Care Respiratory Director, Medical Committee Nominating Thoracic Society American (ATS) Member, Associate Director, Division of Respiratory Medicine, Children’s Medicine, Respiratory of Division Director, Associate Options,” Center for Silver Therapeutics Research, Akron, OH, July 2010 July OH, Akron, Research, Therapeutics Silver for Center Options,” Southwestern UT Pediatrics, of Department Chairman, Vice Children’s Affairs, Medical for President Vice Executive UT Southwestern Services Development, Program Pediatric and Dean for Associate UT Southwestern Medicine, Respiratory Pediatric of Division Director, Interim Program Grant CTSA Pilot Chairman, Radiology of Chair Committee Search Co-Chair, Grant T32 Training Director, Associate Directors Board of Children for Anesthesiologist Chairman, “Evaluating the Evidence for Management of RSV Bronchiolitis,” Annual Respiratory Care Week Regional Regional Week Care Respiratory Annual RSV Bronchiolitis,” of Management for the Evidence “Evaluating Dallas, TX, October 2010 Seminar, “Common Drug Resistant Pathogens in the Cystic Fibrosis Fibrosis the in Cystic Pathogens Drug Resistant “Common Olatunji W. Williams, M.D. Williams, W. Olatunji t t t Peter N. Schochet, M.D. Peter t t t M. Rivera-Sanchez, M.D. Yadira t t t S. Kamal Naqvi, M.D. Naqvi, S. Kamal t Tanya M. Martinez-Fernandez, M.D. Tanya t t Peter M. Luckett, M.D. M. Luckett, Peter t t t Andrew S. Gelfand, M.D. t t t Carolyn L. Cannon, M.D., Ph.D. Carolyn M.D., L. Cannon, t t t t t t t t t Major Administrative or Leadership Responsibilities Major Administrative M.D. Fontán, Pérez Julio t t M.D. M. Luckett, Peter Carolyn L. Cannon, M.D., Ph.D. Carolyn M.D., L. Cannon, Presentations/Teaching Activities Presentations/Teaching UT at residents and medical students in teaching engage actively division Medicine the Respiratory of Members Southwestern. 178 Respiratory Medicine t M.D. Naqvi, Kamal S. t M.D., Cannon, Ph.D. L. Carolyn Awards andHonors Achieved American Board of Pediatrics Certification, Sub-board in Sleep Sub-board Medicine Certification, of Board Pediatrics Achieved American Officer, Scientific Chief NorTech InnovationAward WileyInc. CEO to Nebusil, PhD Youngs, Rheumatology 179 Director, Pediatric Rheumatology Pediatric Director, Marilynn G. Punaro, M.D. Marilynn G. Punaro, Nature al therapist, an occupational therapist and a dietician. the highest ranked science journalthe ranked highest in the world. science article the of best pediatricians as one Rheumatology magazine in 2008 and 2010, In 2009. May was published in 2010 in in 2010 was published D Magazine Texas Monthly Texas Translational research by our division that impacts our patient care our patient impacts that division our by research Translational Dr. Punaro wasDr. in feathured a in Dallas. was She invited the by American Rheumatology College of serve to as an expert in the development of treatment guidelines for juvenile arthritis and also was selected as an international expert in serve to a pediatric on lupus committeemeasures. establishingoutcome definitionsfor Faculty Marilynn Pediatric is Director of Rheumatology G. Punaro, Professor, M.D., at UT Southwestern. Punaro’s Dr. clinical interests focus on juvenile arthritis, scleroderma, systemic arthritislupus, and vasculitis. Principal is the She Site several for NIHInvestigator trials treatment and systemic onset lupus for arthritis. Dr. Punaro in Pediatrics was She a resident Medicine, Orleans,of New Louisiana, in 1977. received her medicalat UT Southwestern/Children’s from 1977 to 1980 and held a fellowship degree in from TulanePediatric Punaro Rheumatology Dr. UT 1982. at to Southwestern from 1980 University Schoolis the the elected of leader pediatric rheumatology program directors andthe pediatric for the rheumatology to elected Council representative Pediatric of Subspecialties. was She elected Best to Doctors in America and was named a by Doctor Super Texas Individual disease-specificsheets, to flow the unique clinic, trackingallow of across care allaspects patient’s of a time. They also functioncarepreventive quality to as attention and careprompting maps, of care.Theseindicators include evaluation health, bone of assessment coronary of risk factors in patients, lupus assessment pneumococcal of immunization in immunosuppressed patients, radiographic surveillance for bone erosions in arthritis ophthalmologic exams for a schedule assess to uveitis, retinal patients, vasculitis the and drug Additionally, and possible toxicity. Rheumatology division is involved in both translational and clinical research, with 60 percent of patientsin a research study. participating The rheumatology clinics at Children’s Medical rheumatology clinicsTexasThe Dallas Center Scottish Children’s at Children for Hospital and (TSRHC) Rite thestrive highest provide to qualitycare of theirmultidisciplinary to The patients. teamincludes threenow TSRHCat two pediatric coordinators, nurse practitioners, nurse a physic physical exams consults ensure a standardized newfor history, patient Disease-specific and templates and thorough collection of information from each patient on each clinic visit. Patient-reported outcomes are monitored with visualanalog scales questionnaires. and The division was one of of The one wasthe division Dr. first pediatric rheumatology subspecialtiesby 1950s founded in in the country, the theChester Fink, of first one pediatricrheumatologists elected a Master as of the American of College Rheumatology. than trained has divisions head more continuously It 20 from all for now years, fellows the whom manyof world over theirof own. The Arthritis Clinic,Fink 1950s,also has established Dr. by in seen few patients late a grown the from the largest of country’s clinicsonly a half-day one to children each month for with rheumatic diseases. The Division of Pediatricof Division The PediatricRheumatologyat servesUT for Southwestern resource as Rheumatology major the clinics Its in are North unique inTexas. the and are region staffed by only board-certifiedthe pediatricrheumatologists Texas. North in 180 Rheumatology 3rd Year Post-doctoral Fellows ai cec fjvnl dermatomyositis of science juvenile Basic Research interests: Andrew Shulman, M.D. Vitamin in lupus Ddeficiency Research interests: Katie L. Stewart, M.D. Clinical Sciences, 2006-2007 Clinical Sciences, Southwestern, Fellow, Pediatric Rheumatology, 2005-2008;K-30Graduate Certificate Student, Post-doctoral training: 2009 Education: characteristics of children with oligoarthritis that predict response apoor to therapy Clinical/research expertise: Clinical/research Assistant Professor Alisa C.Gotte, M.D., M.S.C.S. 2002; Resident, Pediatrics, 2002-2004;Fellow, Pediatric Rheumatology, 2005-2008 Post-doctoral training: of Medicine, Philadelphia, M.S.,2006-present Hahnemann of Medicine, School Philadelphia, M.D., 2001;University of Pennsylvania School Education: pediatric systemic in lupusdeficiency erythematosus expertise: Clinical/research Assistant Professor Tracey B. Wright, M.D. Pediatrics, 2001-2004; Children’s Hospital MA,Fellow, Boston, Pediatric Rheumatology, 2004-2007 Post-doctoral training: 2008-2011 Sciences, University, Syracuse, M.D., Ph.D., 2001,UTSouthwestern, ClinicalResearch Scholar, Clinical Education: late-onset juvenile psoriatic arthritis expertise: Clinical/research Assistant Professor Matthew L.Stoll, M.D., Ph.D. Southwestern, Fellow, Pediatric Rheumatology, 2006-2009 Post-doctoral training: M.D., 2003 Education: symptomatology lupus inpediatric patients expertise: Clinical/research Instructor Lorien Nassi, M.D. UTAustin, B.A., 1998;UTSouthwestern, M.D., 2002;UTSouthwestern, M.S.C.S., Yale University, New Haven, CT, B.S., 1997;Medical College of Pennsylvania- Wesleyan University, Middletown, CT, B.A., 1994;SUNY Upstate Medical Stanford University, Palo Alto, CA,B.A., UTSouthwestern/Children’s, Resident, Pediatrics, 2002-2005;UT TheChildren’s Hospital of Philadelphia, PA, Intern, Pediatrics, 2001- Long Island Jewish Medical Center, New Hyde Park, NY, Resident, UTSouthwestern/Children’s, Resident, Pediatrics, 2003-2006;UT Juvenile idiopathic arthritis, clinical genetic and immunologic Health disparities obesity and inrheumatic Vitamin disease, D Subgroups within juvenile idiopathic arthritis, early-onset versus Pediatric rheumatology, psychological and cognitive We are accredited programs for fellowship training one one with honors with Antiphospholipid antibodies Research interests: Umer,Sarwat M.D. of only of in Pediatricin Rheumatology. , 1999;UTSouthwestern, 30 Rheumatology 181
lupus patients Why corticosteroids help UTResearchers at have Southwestern the biologicaluncovered large why rationale for corticosteroids of doses given repeatedly over several help weeks may lupus, with individuals inflammatorya chronic disease that affectsmore than 1 million in people U.S. the Ashley CooperAshley M.D. interests: Research disease rheumatic Genetics of (Children’s) (Children’s)
ilonacept R f O Pediatric Nurse Practitioner/Research Assistant (TSRHC) Assistant Practitioner/Research Nurse Pediatric Pediatric Nurse Practitioner/Research Assistant (TSRHC) Assistant Practitioner/Research Nurse Pediatric hase study P (Children’s) Nurse Coordinator (TSRHC) Coordinator Nurse (Children’s) lacebo Nurse Coordinator (TSRHC) Coordinator Nurse P Julie Fuller, M.D. Fuller, Julie interests: Research dermatomyositis Juvenile Patient Access Representative Access Patient reatment of systemic juvenile idiopathic T ndomized arthritis (RAPPORT) in the the in Development of autoimmunity of during pubertyDevelopment RA such as obesity modify may problems Nutrition-related potential in because of pediatric lupus outcomes the cardiovascular risk increased to of contribution disease. cross-sectional A pilot, study examine to the prevalence and determinants obesity of and insulin resistance in pediatric SLE is near completion. The assessment, using and body composition nutrition and has anthropometry, body DXA revealed whole greater adiposity in children with SLE compared analysis Future controls. to will clarify of the role useglucocorticoid and disease specific to factors the risk obesity of and in dyslipidemia pediatric SLE. The Rheumatology division also is participating in NIH-fundedtwo trials multi-site, in pediatric SLE: t The use of gene-expression analysis in children with systemic onset juvenile idiopathic arthritis(SOJIA) this of performedmembers division great has advances to led in the by understanding This this of the of disorder. pathophysiology antagonist anakinra receptor SOJIA, treatment of for (IL-1) theinsight of directed Interleukin-1 application the novel efficacy evidence the of long-term impressive and which provided safety ofanakinra in of thechildren treatment with Rilonacept, also has blocker, been studiedSOJIA. Another in IL-1 I trial. a Phase analysis Gene-expression hasbeen the to applied study children of with erythematosus systemic and, lupus again, (SLE) important has provided insight mechanisms identifying potential by into in pathophysiologic these production 1 interferon patients increased Type withthat correlated clinical disease activity. t The DivisionPediatric of Rheumatology is actively involved in both translational and clinical research understanding,endeavors in a varietydirected and improving outcomes pathophysiologic options treatment pediatric toward of disorders. rheumatologic Research Activities Research Heather M. Benham, ND, RN, CPNP, RN, CPNP, M. Benham,ND, Heather Clinical Research Staff Clinical Research RN, PNP, Shirley H. Henry, RN, Wesley, Jolene LVN, Alex Almanza, Terry Spencer, RN, Spencer, Terry Elizabet Pullman, RN, Salazar, Laura 2nd year 2nd year 1st 182 Rheumatology teaching for fellows. This elective has been very popular with residents.with popular been for has very elective fellows.teaching This didactic conferences offering Residents encouraged to clinical attend for are elective. the curriculum as Dr. Punaro been developed has by material, original including aboutfaculty. Anotebook rheumatic disease, of articles selected of thethe supervision one theunder members of rheumatology of residentsThe see in clinics pediatric outpatients t t t to: are elective this of The objectives students. medical fourth-year and residents for isavailable pediatric A rheumatologyelective services. of inpatient consultation conferencespart as and clinical departmental regular residents the in for pediatric the teaching directs and of rheumatology basics on the residents for pediatric the teaching provides didactic It assessment of also the and rheumatic diseases. system musculoskeletal of the evaluation residents the in to pediatric divisionthe The major provides instruction Presentations/Teaching Activities at Children’s.managed affecting multiple organ systems, diseases rheumatic Patients at with TSRHC. dermatomyositis managed are scleroderma, and juvenile arthritis, such as systemic lupus, and thosecomponent, as such musculoskeletal primary a with Those patients who diseases havewith defined clearly rheumatic benign causes of musculoskeletal pain are systemic lupus. with thosevisits per patient year,new and 500 than morewith patients, new evaluate primarily clinics These week. also operatedays per four at Children’s Outpatient clinics perweek. by faculty oneatrheumatology least staffed clinic members staff rheumatology faculty pediatric at all TSRHC and Services of Dr. isDirector Arthritis per week. Punaro clinics half-day six in new peryear, patient outpatient approximately approximately visits visits in 3,500 400 including seen major patients are about the site active as Currently 1,500 for served outpatient has TSRHC Historically, clinics. drugs. other or cyclophosphamide steroid, of pulses intravenous for time of period short a for or rehabilitation, for and intensive may or therapy physical beadmitted occupational Clinic Patients Rheumatology TSRHC at the problems.diagnostic or have moreare difficult ill acutely lupus patients They patients seenfor and with consultation who for have services. other primarily beenadmitted are given.Inpatientstherapy of Children’sat types the and illness the the acuteness of in significantly vary hospitals two there inpatient the admissionwere 430 at types of consultations/admissionsyear This at Children’s The and TSRHC. Activities Clinical project sponsored gene by expression collaborators our examines which patterns. atranslational in lupus of acohort of participating pediatric for characterization epidemiological used the being also induction therapy. of during glucocorticoids use data is The the characterizing and disease factors for cardiovascular risk traditional iselucidating followed SLE analysis atwith center data our 1994 the since have Currently beenenrolled. features and outcomes of subjects autoimmune with connective Since tissue disease. 2009, approximately subjects 200 the clinical isacomprehensivedisease Rheumatic designed to characterize database for Pediatric Registry The Dallas dermatomyositis, SLE scleroderma and categories: disease juvenilevascular arthritis, major collagen patients all from discuss and Examine of rheumatologic patients evaluation acomplete aphysical and jointLearn examination in childhood arthritis of diagnosis differential Develop aworking e ains 910 798 4,537 430 New patients Juvenile patients arthritis receiving treatment Inpatient consultations/admissions year per by staff handled Outpatient clinicvisits ceoem 59 95 117 588 1,653 Miscellaneous Rheumatic Diseases Other Scleroderma Dermatomyositis Systemic Lupus ueieAtrts 794 Arthritis Juvenile 2010 Active Rheumatology Patients Rheumatology 183 2010
Fibroblast-Like Synoviocytes,” American College of College of American Synoviocytes,” Fibroblast-Like 2010
Course Director, Pediatric RheumatologyCourse Director, Fourth-year Elective Students for Pediatric RheumatologyCourse Director, Pediatric Elective Residents for Pediatric Rheumatology 17th European Society Bedside,” to Bench Annual Lupus: “Pediatric Congress, Spain, September 2010 Valencia, and New Coming“What’s in Arthritis Juvenile Research” and “Milestones in Pediatric Rheumatology: Where Arthritis Are Going,” Are, Where We Been, Where Have We Arthritis Juvenile Foundation We Conference, TX, September Grapevine, Punaro L, Gotte C, Blankenship Stoll ML, DN, Allantaz “Clinical Z, Xu Pascual and Microarray F, V, Follow- treated SOJIA with Patients of up Anakinra: Pediatric Lessons 17th Learned Over the Past Seven Years,” Rheumatology Presentation) (Podium European Society Spain, Congress, 2010 September Valencia, Mieszkalski E,Schanberg Evans GW, LE, Ebehard KL, Barnhart CI, Sandborg Yow NT, Ilowite HX, Ardoin SP, E, Scheven Silverman E, Von Bowyer Kimura SL, Punaro LF, A, Imundo Y, L, McCurdy Sherry Singer NG, DD, L, Higgins Klein-GittelmanD, GC, Brunner CA, Silver R, M, Wallace HI, L, Jung Wagner-Weiner Soep JB, Carotid Atorvastatin C, of “Does Intimal Investigators, and Progression APPLE Reduce MedialReed A, Tegler (CIMT)Thickening Pediatric Childhoodin in Lupus Results SLE? Prevention Atherosclerosis from the American Randomized, College of Placebo-Controlled Study,” Multicenter, A Double-Blind Trial: (APPLE) Presentation) (Podium Rheumatology Annual 74th Meeting, Scientific Atlanta, 2010 November GA W, JP, PrahaladHinks MarionSudman M, A, SD, JF, M, Haas BohnsackS, Ramos PS,Thomson Thompson Langefeld C and Glass T, M, Howard M, Keddache M, Wagner C,Wise Ryan Punaro M, Tsoras CD, Rose MG, Arthritis Idiopathic Juvenile Association Study for 3q13 Region Chromosome Identifies Genome-Wide “A DN, Near the T Cell Co-Stimulatory American Receptor CD80,” Molecule Rheumatology College Annual of 74th Presentation) (Podium Meeting,Scientific Atlanta,2010 November GA, Mina B A, Giannini M, Eberhard R, Beresford EH, Levy Pilkington DM, C, Punaro RavelliAO, MG, A, Reiff Saad-Magalhaes LB, C, Klein-Gitelman Schanberg LE, Brunner Ying SL, MS, J, J, Tucker Nelson Eaton HI, “Preliminary Global Criteria Disease for Flares Erythematosus Lupus in Systemic Juvenile “American (jSLE), Presentation) (Poster Rheumatology Annual College of 74th Meeting, Scientific Atlanta, 2010 November GA, O’Neil KM, Kickingbird“Pre-PubertalT, LM, Zeft AS,BrunnerBL, Wright H, Myones PunaroLi SC MG, and Erythematosus Lupus Onset Systemic in Girls: Clinical Manifestations and Serologic Post-Pubertal Differ from AmericanOnset SLE,” Rheumatology Annual College of 74th Meeting, Scientific Atlanta,2010 November GA, Presentation) (Poster Mina Klein-Gitleman R, Brunner H, Eberhard A, Punaro MS, Hsu JJ, Moorthy Ardoin SP, MG, LN, Wagner- L, MuscalWeiner E, E and Radhakrishna Scheven Von Schanberg Palter J, SM, L, NT, CA, Ilowite Wallace Standardized of Treatment the Development CARRAthe for Disease-Specific“Towards Lupus Group, American Erythematous Proliferative Nephritis Lupus College of Systemic in for Juvenile Protocols (jSLE),” Presentation) Rheumatology(Poster Annual 74th Meeting, Scientific Atlanta, 2010 November GA, B, Flato D, M, Reuschel E, Shivers C, Punaro EM, Becker Behrens ML, Wise H, Lie BA, TH, Zhang Finkel Genes by Predisposition JIA of Replication and H, “Discovery Hakonarson and Ellis J, J, Munro O, Forre in Candidates of Validation and Association Genome-Wide Rheumatology 74th Annual Scientific Meeting, Atlanta, GA, November 2010 (Podium Presentation) 2010 (Podium November GA, Atlanta, Meeting, Scientific 74thRheumatology Annual Arthritis,”“Juvenile Pediatric TX, Grand Fort Hospital, Worth, December Rounds,Cooks Children’s “Juvenile Dermatomyositis,” Pediatric Physical Medicine and Rehabilitation Lecture Series, UT Southwestern, Series, Lecture UT Southwestern, Rehabilitation and Medicine Physical Pediatric Dermatomyositis,” “Juvenile October 2010 TSRHC, OTs, and School-based PTs for Conference X Medical Regional Diseases,” Tissue Connective “Pediatric 2010 January 2010 April UT Southwestern, Conference, Fellows Rheumatology in Pediatrics,” Research “Clinical August 2010 UT Southwestern, Noon Conference, Gastroenterology Arthritis,” and Inflammation “Gut Marilynn G. Punaro, M.D. Punaro, G. Marilynn t t t t Trainees in Trainees other departments also time spend in the rheumatology clinics. in Residents Physical Medicine and other their of specialties some training receive may through the training, division. In resident additionto the division training only programs 30 accredited fellowship of has for one Punaro in Pediatric Dr. is Program Rheumatology. theDirector Pediatric for Rheumatology program, fellowship and serves she as faculty the Internal for Medicine Rheumatology trainingprogram. t t t t t t t t Alisa C. Gotte, M.D., M.S.C.S. M.D., Alisa C. Gotte, t Ph.D. M.D., L. Stoll, Matthew t t t 184 Rheumatology t Matthew L.Stoll, M.D., Ph.D. t Alisa C.Gotte, M.D., M.S.C.S. t t Marilynn G.Punaro, M.D. Awards and Honors t t Marilynn G.Punaro, M.D. Major Administrative Responsibilities orLeadership t t Alisa C.Gotte, M.D., M.S.C.S. t t t t t Tracey B. Wright, M.D. t Clinical Research Scholar, Department UTSouthwestern, of ClinicalSciences, 2008-2011 Clinical Research Scholar, Department UTSouthwestern, of ClinicalSciences, 2007-2010 inAmerica Doctors Best Texas Super Doctor, Texas Monthly Rheumatology Representative (elected), Co Member, Committee on Education, American College of Rheumatology “Kids Spondyloarthritis, Get too!,” Rheumatolog Assistant Program Director, Pediatric Rheumatology Fellowship Training Program, UTSouthwestern Chief, Pediatric Rheumatology, Children’s Director, TSHRC Services, Arthritis Program Director, Pediatric Rheumatology Fellowship Training Program, UTSouthwestern Division Director, Pediatric Rheumatology, UTSouthwestern Southwestern Medical Student Research Forum, January 2010(Poster Presentations) Risk Factors for Premature Atherosclerosis Are Prevalent inPediatric Systemic Lupus Erythematosus,” UT Obesity inPediatric Systemic Lupus Erythematosus” and Carroll B, Punaro Mand Casanova V, Punaro Mand Alabama, Birmingham, 2010 December “Mucosal Immunity inand Outcome of Spondyloarthritis,” Rheumatology Grand Rounds, University of Wright T , “An Assessment of Demographic and Environmentl RiskFactors for uncil of Pediatric Subspecialties (CoPS) y Grand Rounds, UTSouthwestern, September 2010 Wright T , “Traditional Grants 185 TJO;FCSBĕTI *OKVSZ Grants JPDIFNJDBM$IBOHFTPGćFSNBM /*) 1(. 65)FBMUI4DJFODF$FOUFS)PVTUPO ))48BTIJOHUPO6OJWFSTJUZ ))4/$ o /*) 3(. o )34" $)' o /*) 5$" /*) 6)- o ",)(-6 ,%," o /*) 3%," o /*) 3%," o /*) 3$" %FQBSUNFOUPG4UBUF)FBMUI4FSWJDFT )34" ))" )34" ))" Matthew J. 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Quinn, M.D., M.S. Quinn, M.D., T. Charles t 4JMFOU$FSFCSBM*OGBSDU.VMUJDFOUFS$MJOJDBM5SJBM 86 Marilynn G. Punaro, M.D. Marilynn G. Punaro, t 4BGFUZBOE&ďDBDZPG- t 5SJBMPG&BSMZ"HHSFTTJWFćFSBQZJO+VWFOJMF*EJPQBUIJD"SUIS t 4JMFOU$FSFCSBM*OGBSDU.VMUJDFOUFS$MJOJDBM5SJBM 86 Matthew Porteus, M.D., Ph.D. M.D., Porteus, Matthew t /BOPNFEJDJOF$FOUFSGPS/VDMFPQSPUFJO.BDIJOFT Pamela J. Okada, M.D. Okada, J. Pamela t -PSB[FQBN&ďDBDZBOE4BGFUZ4UVEZ t 1FEJBUSJD5SBVNBUJD#SBJO*OKVSZ$POTPSUJVN)ZQPUIFSNJB t &.4$5BSHFUFE*TTVF(SBOU Lynn Mahony, M.D. Mahony, Lynn t 1FEJBUSJD)FBSU%JTFBTF$MJOJDBM3FTFBSDI/FUXPSL t 1SFWFOUJPOPG$PNQMJDBUJPOTPG#MFFEJOH%JTPSEFSćSPVHI)FNPQ t 3FHJPO*7$PNQSFIFOTJWF)FNPQIJMJB1SPHSBN M.D. Lister, George t 4UVEZPG"UUJUVEFTBOE'BDUPST"ČFDUJOH*OGBOU$BSF t $POUSBDU4FSWJDFTGPSUIF3&"$)$MJOJD t 'FMMPXTIJQGPS3PCFSU4JMHF Janna Journeycake, M.D., M.S. 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Winick, M.D. $ISPOJD3FOBM*OTVďDJFODZJO/BQSUDT t 0QUJNBM5SFBUNFOUPG'PDBM4FHNFOUBM(MPNFSVMPTDMFSPTJT 'THT t Mouin Seikaly, M.D. $POUSPMMFE5SJBMPG-JWF"UUFOVBUFE*OĘVFO[B7BDDJOFJO7FSZ t .VMUJQMF%PTF1IBSNBDPLJOFUJD4UVEZPG.FSPQFOFNJO:PVOH*OG t ćF/BUVSBM)JTUPSZPG$.7SFMBUFE)FBSJOH-PTTBOE'FBTJCJMJU t Pablo M.D. Sanchez, *OUFS1FEJBUSJD/FQISPMPHZ o "ENB#JPMPHJDT "%." 0QFO $BUIPMJD'PVOEBUJPO(1MBUU%8FJS 3PCFSU"8FMDI'PVOEBUJPO o "NFSJDBO$BODFS4PDJFUZ 1' $IBNQJPOTIJQ)FBSUT'PVOEBUJPO /BUJPOBM$IJMEIPPE$BODFS'PVOEBUJPO /BUJPOBM$IJMEIPP 0QFO /BUJPOBM$IJMEIPP /BUJPOBM$IJMEIPP $IJMESFOT.FSDZ)PTQJUBM 6%, 4VOZ4UPOZCSPPL/*) 6%, o 6OJWFSTJUZPG3PDIFTUFS /*)%VLF6OJWFSTJUZ "CEPNJOBM*OGFDUJPOT /*)6OJWFSTJUZPG"MBCBNB#JSNJOHIBN ))4/$ /FXCPSO E$BODFS'PVOEBUJPO 6$" E$BODFS'PVOEBUJPO 6$" E$BODFS'PVOEBUJPO 6$" 1SFNBUVSF*OGBOUT ZPG$.74DSFFOJOHBT"EKVODUUP)FBSJOH4DSFFOJOHJOUIF -PXFS5SBDU347*MMOFTT IJMEIPPE$BODFST BOUT %BZT XJUI4VTQFDUFEPS$PNQMJDBUFE*OUSB Grants 191 FUBCPMJTN EFBOE0SBM5PQPUFDBOGPS$IJMESFOXJUI3FDVSSFOU4PMJE FNBUPMPHZ FT/PWFM3FBHFOUTGPS.POJUPSJOH$BODFS$FMM BDUJWBUFE$IBOOFM5.&." 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Tannin, M.D. Tannin, M. Grace t ćF(FOFUJDTBOE/FVSPFOEPDSJOPMPHZPG4IPSU4UBUVSF*OUFSOBUJ 198 Grants Publications 199 Publications 1. 1. familial recessive Autosomal DH. in neurohypophyseal onset early diabetes infancy. Eur J insipidus: Libdeh Levy-Khademi A, Abu Abdulhadi-Atwan M, Bosin F, Endocrinol;162:221-6. E, M, White Korner PC, Zangen 2. infants in afterpneumoniae very low-birth-weight administration vaccine.pneumococcal heptavalent of conjugate Lua JL, Ang Asmar Shankaran JY, BI, Med;164:1173-5. Arch Pediatr Adolesc et al. S, Heyne RJ, Nasopharyngeal carriage Streptococcus of 3. in pediatric outcome predict heart levels BNP failure analysis post hoc patients: DT. the of Pediatric Carvedilol SR, Richmond ME, Shaddy RE, Auerbach LJ, Lamour L, Addonizio Mahony ED, Trial. Blume JM, Pahl E, Hsu Circ Heart Fail 2010;3(5):606-11. 4. in experimental pancreatic cancer. Cancer Biol Ther;10:99-107. Schwarz Awasthi N, MA, Schwarz RE. 5. effects bortezomibof Combination withgemcitabine and EMAP II optimistic in the current outcome era. Heart Rhythm 2010;7:781-5. RE, Tanel Zeltser AzizAtrioventricular The IJ. Congenital Syndrome QT PF, 2:1 Long and Block: 6. An of Definitionsphenotypic manifestations sicklethe of cell disease. Hematol;85:6-13. J Am Johnson BallasZR,Heeney Hoppe CS,Rogers C, et MM, al. CD, Lieff Dampier SK, S, LJ, Benjamin7. J Pediatr Gastroenterol Nutr;51:680-4. center. Barth Channabasappa BA, 8. Single-balloon in N. children: enteroscopy initial experience a pediatric at with angiotensin Regul II. Am Integr J Physiol Physiol;298:R954-8. Comp Baum M. Effect of medullary catecholamines on rat 9. thick ascending limb chloride transport: interaction 10. Baum M. Overview Oncol;32:525-6. kidney chronic of Hematol disease in children. Curr Opin Pediatr;22:158-60. Baum M. Renal syndrome Fanconi secondaryPediatr there is fire. there J is smoke deferasirox: where to 11. Physiol Renal Physiol;298:F235-47. the of kidney Baum M. Role in the prenatal and early postnatal programming hypertension. of Am J 12. inflammationof model mouse in a viral Respirbronchiolitis. Res;11:90. Beigelman Cannon Azithromycin MJ. A, Mikols CL, SL, attenuates airway CL, Brody Walter Gunsten SP, 13. micafungindose in infants. young Clin Pharmacol Ther;87:93-9. Arrieta Smith PB, A, Castro Benjamin et al. Jr., L, DK, Sanchez Safety PJ, and pharmacokinetics repeat- of 14. risk factors, and clinical Pediatrics;126:e865-73. judgment. et al. MC, Sanchez PJ, Neonatal Gantz candidiasis: Walsh, MG, Stoll BJ, epidemiology, Benjamin Jr., DK, 15. pharmacokinetic studies in children Pediatr phase with 1 consortium Oncology study. Group cancer: a Children’s Berg SL, Winick Ingle N, AM, Adamson PC, Blaney participation Reasons SM. for in optional Blood Cancer;55:119-22. 16. Pediatr;156:687. allergy and urticaria. Peanut hypotension with a patient saves Burks cold-induced JA, W. Bird J 17. pulmonary arterial hypertension. J Card Fail;16:121-7. BlalockSE, Matulevicius S, Mitchell LC, with et al. outcomes ambrisentan in Long-term monotherapy 18. signaling in model. Endocrinology;151:1990-7. the baboon preterm Blanco CL,of Lianginsulin H, Joya-Galeana RA, DeFronzo ontogeny J, The N. McCurnin Musi D, 19. theis helpful echocardiographic for detection anomalous coronary of left artery pulmonary from the artery. J Am Blanco VM, Blalock SE, Ramaciotti C, Lemler Ikemba L, C. M, Heistein J, Oxygen Moore supplementation Echocardiogr;23:1099-102. Soc 20. famciclovir in infants pharmacokinetic and population analysis in infants and children. Antimicrob Agents Rodriguez J, Blumer Kaiser Sallas G, Hamed A, Sanchez PJ, K. Single-dose W, pharmacokinetics of Chemother;54:2032-41. 21. et al. real-time spot Sanchez Dried PJ, polymerase blood chain congenital reaction assays newborns screen for to Palmer AL, Jr., Ahmed Novak Z, SA, Boppana Ross RW SB, A, Michaels Shimamura MG, M, Tolan JAMA;303:1375-82. infection. cytomegalovirus 22. Humans Natl Sci Acad Proc U S A 2010;107(10):2770-5. C, Bouche Lopez X, Fleischman A, et al. Insulin Enhances Glucose-Stimulated Insulin Secretion in Healthy Publications 200 Pediatr BloodPediatr Cancer;55:485-94. Trial Consortium. Comprehensive from areport the Centers disease: Clinical Cell cell Sickle sickle with children LeBeau S, Lieff Dampier C, S, Rhee K, Z, M, McMurray Smith-Whitley Rogers P, the W forWang (CTC).Comprehensive Trial Consortium Centers (CSCC) in of life Cell Sickle Health-related Clinical quality 42. urinary and serum on postnatal dexamethasone of J, Effect Habibprenatal M. Baum S, A,Gattineni Dagan JHypertens;23:420-4. levels. Am II angiotensin 41. in risk of Traditional cardiovascular GR. laboratory measures Troendle N, Buchanan SE, Ahmad S, Crary Blood Cancer;55:684-9. Pediatr spherocytosis. hereditary 40. Suppl 1):S29. al. I, Leibowitz Patel A,et S, Kim S, Grunow J, Duffy Denson L, RB, W, MD, Colletti Kappelman Crandall Improved improvement 2010;138 IBD outcomes Journal aquality Crohns disease. in for collaborative pediatric (5, 39. 2010;138(5):S29. I, Leibowitz Patel A,et S, Kim S, Grunow J, Duffy Denson L, RB, W, MD, Colletti Kappelman Crandall Gastroenterology Improvement Colitis. Improved for Ulcerative Pediatric Collaborative al. aQuality Outcomes in 38. of chest routine Cox JA,utility D, J, Demasi diagnostic Jackson Scothorn McCollom G, The S, Aquino VM. Blood hematopoietic Cancer. fever patients Pediatr undergoing in stemcell. initial of the evaluation the in radiography 37. needs: care health special with for US care Flores Family-centered children G. MA, Rodriguez TR, Coker who why? it gets and Pediatrics;125:1159-67. 36. Ed;96:F99-F101. Hemway C, RJ, Wyckoff method Christman two-finger is two-thumb the superior MH, JM. The to Perlman Neonatal Fetal model of resuscitation. DisChild Arch neonatal chest compressions amanikin in for administering 35. Post-transplant R. lymphoproliferative disorder Sanghavi S, Transplant. Chinnakotla L, Pediatr N, Klesse Fustino Cheng E, nephrectomy? or biopsy Renal dilemma: Diagnostic tumor. Wilms resembling 34. N, Johnson-Welch Channabasappa in a livertransplantation N. Denovo after cholangiocarcinoma Mittal S, Transplant;14:E110-4. patient. Pediatr pediatric 33. Invest;120:2319-30. JClin mice. in but not growth or uterine breast cancer PW. Shaul BS, Katzenellenbogen protection Non-nuclear promotes receptor cardiovascular estrogen signaling alpha ThomasC, M,Korach Umetani GD, KS, ES, Mineo Konaniah Yuhanna Wu S, Q,Oltmann KL, Chambliss SP, A,Dineen SH, Maggi Hui Madak-Erdogan DY, JA, Z, Roland CL, Kim IS, Katzenellenbogen RA, Brekken 32. Res;30:339-47.Cytokine multiple with chemokines Rohatgi A,Ayers of Associations four L, circulating etal. CR, Castillo study. JInterferon heart dallas the from population-based alarge sample: results in atherosclerosis phenotypes 31. JMed;362:1959-69. NEngl preterm infants. extremely in saturation WA, Carlo Walsh W, Finer NN, Rich MC, Yoder MG, Laptook AR, Gantz RG, A,Poole BA, Das Faix WK, AJ, 3rd, PJ, ID Target N, Sanchez Piazza Frantz of etal. oxygen ranges Ambalavanan NS, Schibler K,Newman 30. Pediatrics;125 ASDs. Suppl 1:S19-29. with problems children in oftreatment common gastrointestinal T, Buie Beaudet AL, Fuchs D, GJ, ML, GT, 3rd, Bauman J, Vandewater Furuta Atkins AH, Levy J, Whitaker Jirapinyo P, Gershon SL, EG, MD, Hyman Carr Jyonouchi Recommendations H,Kooros for and K,etal. evaluation 29. Pediatrics;125 ASDs: aconsensus report. Suppl with 1:S1-18. individuals disorders in oftreatment gastrointestinal Buie T, DB, Fuchs GJ, Campbell D, ML, GT, 3rd, J, Bauman Furuta Vandewater Atkins AH, Levy J, Whitaker Jirapinyo Gershon SL, P, EG, MD, Hyman Carr JyonouchiBeaudet and AL, Evaluation, H,Kooros diagnosis, K,etal. 28. (Hoboken);62:811-20. Res Care Arthritis DM, A, Singer Eberhard N, Olson Onel JC, Lapidus SK, Levy GC, Higgins MS, Klein-Gitelman HI, Brunner Toward Metal. systemic lupus in erythematosus. developmentK, Punaro juvenile the flares for of global criteria 27. (Hoboken);62:335-44. Res Care Arthritis of validation Prospective Wiers K,Lapidus M,etal. GC, SK, Olson Onel JC, K,Punaro Higgins HI, Brunner lupus systemic erythematosus. of childhood-onset response forin evaluation to therapy provisional criteria the the 26. (Hoboken);62:950-9. Res Care Arthritis Minimal M,etal. Lapidus MS, SK, Olson Onel JC, K,Punaro Klein-Gitelman GC, Higgins HI, Brunner systemic lupus erythematosus. in childhood-onset indices activity disease of differences important clinically 25. neurofibromasin neurofibromatosis LJ, LQ. predict paraspinal Le features Klesse Cutaneous Brown RM, 1. JInvest Dermatol;130:2167-9.type 24. ependymoma J. mTORC1 childhood in Brugarolas L, act Publications 201 fants weighing nucleotides, Chem;286:766-76. epithelium. J Biol 62. containing Chem;285:8138-47. in epithelium. liver J Biol vesicles Lewis Feranchak MA, AP, Kresge C, Sathe al. M, et purinergic Initiation of signaling exocytosis by ATP- of 63. Newman versus et al. 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