Anti-DDX3X Monoclonal Antibody, Clone JNH22G22E21 (DCABH-3397) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-DDX3X monoclonal antibody, clone JNH22G22E21 (DCABH-3397) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Mouse monoclonal to DDX3

Antigen Description ATP-dependent RNA helicase. Acts as a cofactor for XPO1-mediated nuclear export of incompletely spliced HIV-1 Rev RNAs. Also involved in HIV-1 replication. Interacts specifically with hepatitis C virus core protein resulting in a change in intracellular location.

Immunogen Recombinant fragment corresponding to amino acids 24-203 of Human DDX3 (NP_001347).

Isotype IgG2b

Source/Host Mouse

Species Reactivity Human

Clone JNH22G22E21

Purity Protein G purified

Conjugate Unconjugated

Applications WB, Flow Cyt

Positive Control Recombinant protein (amino acids 24-203) and 293 lysate. MFC7 and HeLa cells.

Format Liquid

Size 100 μg

Buffer Preservative: 0.05% Sodium azide; Constituents: 99% PBS, 0.05% BSA

Preservative 0.05% Sodium Azide

Storage Store at 4°C. Aliquot and store at -20°C long-term.

GENE INFORMATION

Gene Name DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked [ Homo sapiens ]

Official Symbol DDX3X

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Synonyms DDX3X; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked; DDX3, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 3; ATP-dependent RNA helicase DDX3X; DBX; DDX14; HLP2; CAP- Rf; DEAD/H box-3; DEAD box, X isoform; helicase like protein 2; helicase-like protein

Entrez Gene ID 1654

Protein Refseq NP_001180345

UniProt ID O00571

Chromosome Location Xp11.3-p11.23

Pathway RIG-I-like receptor signaling pathway, organism-specific biosystem; RIG-I-like receptor signaling pathway, conserved biosystem; TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem;

Function ATP binding; ATP-dependent RNA helicase activity; DNA binding; RNA binding; helicase activity; hydrolase activity; nucleotide binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]