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The Dominant Anopheles Vectors of Human Malaria in the Asia-Pacific
Sinka et al. Parasites & Vectors 2011, 4:89 http://www.parasitesandvectors.com/content/4/1/89 RESEARCH Open Access The dominant Anopheles vectors of human malaria in the Asia-Pacific region: occurrence data, distribution maps and bionomic précis Marianne E Sinka1*, Michael J Bangs2, Sylvie Manguin3, Theeraphap Chareonviriyaphap4, Anand P Patil1, William H Temperley1, Peter W Gething1, Iqbal RF Elyazar5, Caroline W Kabaria6, Ralph E Harbach7 and Simon I Hay1,6* Abstract Background: The final article in a series of three publications examining the global distribution of 41 dominant vector species (DVS) of malaria is presented here. The first publication examined the DVS from the Americas, with the second covering those species present in Africa, Europe and the Middle East. Here we discuss the 19 DVS of the Asian-Pacific region. This region experiences a high diversity of vector species, many occurring sympatrically, which, combined with the occurrence of a high number of species complexes and suspected species complexes, and behavioural plasticity of many of these major vectors, adds a level of entomological complexity not comparable elsewhere globally. To try and untangle the intricacy of the vectors of this region and to increase the effectiveness of vector control interventions, an understanding of the contemporary distribution of each species, combined with a synthesis of the current knowledge of their behaviour and ecology is needed. Results: Expert opinion (EO) range maps, created with the most up-to-date expert knowledge of each DVS distribution, were combined with a contemporary database of occurrence data and a suite of open access, environmental and climatic variables. -
Production and Characterization of Monoclonal Antibodies to Anopheles Tessellatus Midgut
J. Natn. Sci. Coun. Sri Lanka 1995 23(1): 17-24 PRODUCTION AND CHARACTERIZATION OF MONOCLONAL ANTIBODIES TO ANOPHELES TESSELLATUS MIDGUT MANTHRI S. RAMASAMY1, R. KULASEKERA1, RA. SRIKRISHNARAJ1, JOAN HOOGENRAAD3, N.J. HOOGENRAAD3and R. RAMASAMY ' Molecular Entomology and 21mmunologyLaboratories, Division of Life Sciences, ' Institute of Fundamental Studies, Hantana Road, Kandy. School of Biochemistry, LaTrobe University, Bundoora, Victoria 3083, Australia. (Received :5 August 1994; accepted: 20 January 1995) Abstract: The production of monoclonal antibodies (Mabs) against antigen derived from the midgut ofAnopheles tessellatus is described. Three cloned Mabs examined were found to be directed against conformational epitopes on midgut antigens. Ingestion of these Mabs in a bloodmeal did not affect mosquito mortality or fecundity. The intake of the Mabs, when compared to normal mouse IgG, with a bloodmeal containingPlasmodium vivagametocytes did not reduce the suscept~bilityof the mosquito to parasite infection. Key words: Anopheles tessellatus, conformational epitopes, monoclonal anti- bodies, mosquito midgut. INTRODUCTION The midgut of the mosquito is composed of a single layer of epithelial cells and plays an important role in mosquito-pathogen interactions. The ingested bloodmeal is digested in the lumen ofthe midgut by proteolytic enzymes secreted by midgut epithelial cells.' The sexual stages and ookinetes of the malaria parasite Plasmodium can be damaged by mosquito tryp~in.~The formation of a peritrophic membrane by secretions from -
A Method to Sample Blood-Fed and Host-Seeking Exophilic Mosquitoes
Burkot et al. Malaria Journal 2013, 12:49 http://www.malariajournal.com/content/12/1/49 METHODOLOGY Open Access Barrier screens: a method to sample blood-fed and host-seeking exophilic mosquitoes Thomas R Burkot1,2*, Tanya L Russell1, Lisa J Reimer3,4, Hugo Bugoro5, Nigel W Beebe6,7, Robert D Cooper8, Supraman Sukawati9, Frank H Collins10 and Neil F Lobo10 Abstract Background: Determining the proportion of blood meals on humans by outdoor-feeding and resting mosquitoes is challenging. This is largely due to the difficulty of finding an adequate and unbiased sample of resting, engorged mosquitoes to enable the identification of host blood meal sources. This is particularly difficult in the south-west Pacific countries of Indonesia, the Solomon Islands and Papua New Guinea where thick vegetation constitutes the primary resting sites for the exophilic mosquitoes that are the primary malaria and filariasis vectors. Methods: Barrier screens of shade-cloth netting attached to bamboo poles were constructed between villages and likely areas where mosquitoes might seek blood meals or rest. Flying mosquitoes, obstructed by the barrier screens, would temporarily stop and could then be captured by aspiration at hourly intervals throughout the night. Results: In the three countries where this method was evaluated, blood-fed females of Anopheles farauti, Anopheles bancroftii, Anopheles longirostris, Anopheles sundaicus, Anopheles vagus, Anopheles kochi, Anopheles annularis, Anopheles tessellatus, Culex vishnui, Culex quinquefasciatus and Mansonia spp were collected while resting on the barrier screens. In addition, female Anopheles punctulatus and Armigeres spp as well as male An. farauti, Cx. vishnui, Cx. quinquefasciatus and Aedes species were similarly captured. -
Review of Insecticide Resistance and Behavioral Avoidance of Vectors Of
Chareonviriyaphap et al. Parasites & Vectors 2013, 6:280 http://www.parasitesandvectors.com/content/6/1/280 REVIEW Open Access Review of insecticide resistance and behavioral avoidance of vectors of human diseases in Thailand Theeraphap Chareonviriyaphap1*, Michael J Bangs2, Wannapa Suwonkerd3, Monthathip Kongmee4, Vincent Corbel1,5 and Ratchadawan Ngoen-Klan1 Abstract Physiological resistance and behavioral responses of mosquito vectors to insecticides are critical aspects of the chemical-based disease control equation. The complex interaction between lethal, sub-lethal and excitation/ repellent (‘excito-repellent’) properties of chemicals is typically overlooked in vector management and control programs. The development of “physiological” resistance, metabolic and/or target site modifications, to insecticides has been well documented in many insect groups and disease vectors around the world. In Thailand, resistance in many mosquito populations has developed to all three classes of insecticidal active ingredients currently used for vector control with a majority being synthetic-derived pyrethroids. Evidence of low-grade insecticide resistance requires immediate countermeasures to mitigate further intensification and spread of the genetic mechanisms responsible for resistance. This can take the form of rotation of a different class of chemical, addition of a synergist, mixtures of chemicals or concurrent mosaic application of different classes of chemicals. From the gathered evidence, the distribution and degree of physiological resistance has been restricted in specific areas of Thailand in spite of long-term use of chemicals to control insect pests and disease vectors throughout the country. Most surprisingly, there have been no reported cases of pyrethroid resistance in anopheline populations in the country from 2000 to 2011. The precise reasons for this are unclear but we assume that behavioral avoidance to insecticides may play a significant role in reducing the selection pressure and thus occurrence and spread of insecticide resistance. -
Malaria Journal Biomed Central
Malaria Journal BioMed Central Research Open Access The resting sites and blood-meal sources of Anopheles minimus in Taiwan Mei-Chun Chang1, Hwa-Jen Teng*1, Chen-Fu Chen1, Yung-Chen Chen1 and Chian-Ren Jeng2 Address: 1Research and Diagnostic Center, Centers for Disease Control, Taiwan and 2Department of Veterinary Medicine, National Taiwan University, Taipei, Taiwan Email: Mei-Chun Chang - [email protected]; Hwa-Jen Teng* - [email protected]; Chen-Fu Chen - [email protected]; Yung- Chen Chen - [email protected]; Chian-Ren Jeng - [email protected] * Corresponding author Published: 9 June 2008 Received: 27 February 2008 Accepted: 9 June 2008 Malaria Journal 2008, 7:105 doi:10.1186/1475-2875-7-105 This article is available from: http://www.malariajournal.com/content/7/1/105 © 2008 Chang et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: The WHO declared Taiwan free from malaria in 1965, but in 2003 the reporting of two introduced cases in a rural area suggested a possible local transmission of this disease. Therefore, understanding the resting sites and the blood sources of Anopheles minimus is crucial in order to provide information for implementing vector control strategies. Methods: During a two-year survey, mosquitoes were collected in houses and their surrounding areas and at the bank of larval habitats by backpack aspirators in 17 villages in rural areas of southern and eastern Taiwan for 1 hr. -
Potential Malaria Vector Anopheles Minimus
bioRxiv preprint doi: https://doi.org/10.1101/2020.09.01.277020; this version posted September 1, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-ND 4.0 International license. Potential malaria vector Anopheles minimus (species A) still persisting in North East India Varun Tyagi1, Diganta Goswami2, Sunil Dhiman3*, Dipanjan Dey4, Bipul Rabha2, P. Chattopadhyay1, Sanjai K Dwivedi 1 Division of Pharmaceutical Technology, Defence Research Laboratory, Tezpur-784001, Assam, India 2 Medical Entomology Division, Defence Research Laboratory, Tezpur-784001, Assam, India 3 Vector Management Division, Defence Research & Development Establishment, Gwalior- 474002, Madhya Pradesh 4 Cotton College State University, Panbazar, Guwahati-781001, Assam *Corresponding Author- [email protected] 1 bioRxiv preprint doi: https://doi.org/10.1101/2020.09.01.277020; this version posted September 1, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-ND 4.0 International license. ABSTRACT Background: Vector borne infectious diseases affect two third of the world’s human population and cause mortality in millions each year. Malaria remains one of the major killers in the Indian sub- continent and transmitted uninterruptedly by many efficient vectors and their sibling species. In North East India (NE), Anopheles minimus has been recognized as an important vector which shares majority of malaria cases. -
Anopheline Species Complexes in South and South-East Asia WHO Library Cataloguing-In-Publication Data World Health Organization, Regional Office for South-East Asia
SEARO Technical Publication No. 57 Vector-borne diseases are a major health problem in the South-East Asia Region and in other parts of the world. There are about 4 500 mosquito species in existence; species belonging to the Anopheles genus transmit malaria. Combating malaria is part of the Millenium Development Goals, and vector control is a key strategy both regionally and globally. Therefore, the review and dissemination of information on vector species is critically important. Most of the anophelines that are involved in the transmission of malaria in South and South-East Asia have been identified as species complexes. Members of a species complex are reproductively isolated evolutionary units with distinct gene pools and, hence, they differ in their biological characteristics. In 1998, WHO published Anopheline species complexes in South-East Asia. New identification tools have been developed since then, and therefore this updated edition is being published. It summarizes work that has been done on anopheline cryptic species and will be highly valuable to researchers, field entomologists and malaria- control programme managers. AAnnoopphheelliinnee SSppeecciieess CCoommpplleexxeess iinn SSoouutthh aanndd SSoouutthh--EEaasstt AAssiiaa ISBN 978-92-9022-294-1 9 7 8 9 2 9 0 2 2 2 9 4 1 SEARO Technical Publication No. 57 Anopheline Species Complexes in South and South-East Asia WHO Library Cataloguing-in-Publication data World Health Organization, Regional Office for South-East Asia. Anopheline Species Complexes in South and South-East Asia. 1. Anopheles 2. Species Specificity 3. Sibling Relations 4. Insect Vectors 5. South-East Asia 6. Asia, Western ISBN 978-92-9022-294-1 NLM Classification No. -
Laboratories of Analytical Biology Publications from 2020 Publications Listed in Alphabetical Order
Laboratories of Analytical Biology Publications from 2020 Publications listed in alphabetical order Ames, C.L., Klompen, A.M.L., Badhiwala, K. et al. A Collins… (2020) "Cassiosomes are stinging- cell structures in the mucus of the upside-down jellyfish Cassiopea xamachana." Commun Biol 3, 67 doi:10.1038/s42003-020-0777-8 Appelhans MS, Wen J. 2020. Phylogenetic placement of Ivodea and biogeographic affinities of Malagasy Rutaceae. Plant Systematics and Evolution 306 (1): Article 7. doi:10.1007/s00606-020- 01633-3 Atkinson, CL, van Ee, BC and Pfeiffer, JM. 2020. Evolutionary history drives aspects of stoichiometric niche variation and functional effects within a guild. Ecology, 101(9), p.e03100. DOI:10.1002/ecy.3100 Bakkegard, KJ, D Johnson, and DG Mulcahy. 2020. A New Locality, Naval Station Guantanamo Bay, for the Rare Lizard Leiocephalus onaneyi (Guantánamo Striped Curlytail) and Notes on its Natural History. Caribbean Naturalist 79: 1–22. Barnett, R., Westbury, M.V., Sandoval-Velasco, M., Vieira, F.G., Jeon, S., Zazula, G., Martin, M.D., Ho, Simon Y. W., Mather, N., Gopalakrishnan, S., Ramos-Madrigal, J., de Manuel, M., Zepeda-Mendoza, M. Lisandra, Antunes, Agostinho, Baez, Aldo Carmona, De Cahsan, Binia, Larson, Greger, O'Brien, Stephen J., Eizirik, Eduardo, Johnson, W.E., Koepfli, K.-P., Wilting, A., Fickel, J., Dalen, L., Lorenzen, E. D., et al. 2020. Genomic Adaptations and Evolutionary History of the Extinct Scimitar-Toothed Cat, Homotherium latidens. Current Biology. doi:10.1016/j.cub.2020.09.051 Barrett RL, Peterson PM, Romaschenko K. 2020. A molecular phylogeny of Eragrostis(Poaceae: Chloridoideae: Eragrostideae): making lovegrass monophyletic in Australia. -
Qt7rn2g80n.Pdf
UC Irvine UC Irvine Previously Published Works Title The second internal transcribed spacer of nuclear ribosomal DNA as a tool for Latin American anopheline taxonomy: a critical review Permalink https://escholarship.org/uc/item/7rn2g80n Journal Memórias do Instituto Oswaldo Cruz, 101(8) ISSN 0074-0276 Authors Marrelli, Mauro Toledo Sallum, Maria Anice Mureb Marinotti, Osvaldo Publication Date 2006-12-01 DOI 10.1590/S0074-02762006000800002 Peer reviewed eScholarship.org Powered by the California Digital Library University of California Mem Inst Oswaldo Cruz, Rio de Janeiro, Vol. 101(8): 817-832, December 2006 817 The second internal transcribed spacer of nuclear ribosomal DNA as a tool for Latin American anopheline taxonomy - A critical review Mauro Toledo Marrelli, Maria Anice Mureb Sallum, Osvaldo Marinotti*/+ Departamento de Epidemiologia, Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, SP, Brasil *Department of Molecular Biology and Biochemistry, University of California Irvine McGaugh Hall, Room 2315, 92697-3900, Irvine, CA, US Among the molecular markers commonly used for mosquito taxonomy, the internal transcribed spacer 2 (ITS2) of the ribosomal DNA is useful for distinguishing among closely-related species. Here we review 178 GenBank accession numbers matching ITS2 sequences of Latin American anophelines. Among those, we found 105 unique sequences corresponding to 35 species. Overall the ITS2 sequences distinguish anopheline species, however, information on intraspecific and geographic variations is scarce. Intraspecific variations ranged from 0.2% to 19% and our analysis indicates that misidentification and/or sequencing errors could be responsible for some of the high values of divergence. Research in Latin American malaria vector taxonomy profited from molecular data provided by single or few field capture mosquitoes. -
Anopheles Ecology, Genetics and Malaria Transmission in Northern Cambodia Amélie Vantaux 1,8*, Michelle M
www.nature.com/scientificreports OPEN Anopheles ecology, genetics and malaria transmission in northern Cambodia Amélie Vantaux 1,8*, Michelle M. Riehle 2,8, Eakpor Piv1, Elise J. Farley2, Sophy Chy1, Saorin Kim1, Anneli G. Corbett2, Rachel L. Fehrman 2, Anais Pepey 1, Karin Eiglmeier 3,4, Dysoley Lek5,6, Sovannaroth Siv5, Ivo Mueller7, Kenneth D. Vernick 3,4,9 & Benoit Witkowski1,9 In the Greater Mekong Subregion, malaria cases have signifcantly decreased but little is known about the vectors or mechanisms responsible for residual malaria transmission. We analysed a total of 3920 Anopheles mosquitoes collected during the rainy and dry seasons from four ecological settings in Cambodia (villages, forested areas near villages, rubber tree plantations and forest sites). Using odor- baited traps, 81% of the total samples across all sites were collected in cow baited traps, although 67% of the samples attracted by human baited traps were collected in forest sites. Overall, 20% of collected Anopheles were active during the day, with increased day biting during the dry season. 3131 samples were identifed morphologically as 14 diferent species, and a subset was also identifed by DNA amplicon sequencing allowing determination of 29 Anopheles species. The investigation of well characterized insecticide mutations (ace-1, kdr, and rdl genes) indicated that individuals carried mutations associated with response to all the diferent classes of insecticides. There also appeared to be a non-random association between mosquito species and insecticide resistance with Anopheles peditaeniatus exhibiting nearly fxed mutations. Molecular screening for Plasmodium sp. presence indicated that 3.6% of collected Anopheles were positive, most for P. -
Current Arboviral Threats and Their Potential Vectors in Thailand
pathogens Review Current Arboviral Threats and Their Potential Vectors in Thailand Chadchalerm Raksakoon 1 and Rutcharin Potiwat 2,* 1 Department of Chemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand; [email protected] 2 Department of Medical Entomology, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand * Correspondence: [email protected] Abstract: Arthropod-borne viral diseases (arboviruses) are a public-health concern in many regions of the world, including Thailand. This review describes the potential vectors and important human and/or veterinary arboviruses in Thailand. The medically important arboviruses affect humans, while veterinary arboviruses affect livestock and the economy. The main vectors described are mosquitoes, but other arthropods have been reported. Important mosquito-borne arboviruses are transmitted mainly by members of the genus Aedes (e.g., dengue, chikungunya, and Zika virus) and Culex (e.g., Japanese encephalitis, Tembusu and West Nile virus). While mosquitoes are important vectors, arboviruses are transmitted via other vectors, such as sand flies, ticks, cimicids (Family Cimi- cidae) and Culicoides. Veterinary arboviruses are reported in this review, e.g., duck Tembusu virus (DTMUV), Kaeng Khoi virus (KKV), and African horse sickness virus (AHSV). During arbovirus outbreaks, to target control interventions appropriately, it is critical to identify the vector(s) involved and their ecology. Knowledge of the prevalence of these viruses, and the potential for viral infections to co-circulate in mosquitoes, is also important for outbreak prediction. Keywords: emerging infectious diseases; arboviruses; vector; Aedes spp.; veterinary Citation: Raksakoon, C.; Potiwat, R. 1. Introduction Current Arboviral Threats and Their Arboviral diseases impact human and/or veterinary health in Thailand. -
7 Stituted Are”Discussed Later in This
Voi.II No. 7 Chief lialariologist, Hq AFPAC, APO 500 23 June 19U5 Observations of Preventive Medicine Situation on Okinawa ■ from L day to' L*60 Filariasis is the most serious hazard to troop health. About 2~> per cent of native Okinawans are carrying micro-filaria of a nocturnal variety in their blood streams. The mosquito vector of this disease, Culex quinquefasciatus, is present in large numbers. Five per cent of 6p0 of these mosquitoes were found to harbor filarial worms. The population of this infected mosquito is increas- ing in abandoned native villages and will probably be greater as combat areas and towns in the southern end of the island are occupied. It is to be emphasized that the manifestations of filariasis do not develop until 3 to 9 months after exposure. A false sense of security may thus lead to laxity of control measures and result in serious impairment of troop efficiency in the future. Schistosomiasis is probably of no importance. None of the native Okinawans and only one Japanese have been found to carry eggs of Schistosoma japonicum in about 300 stool examinations. No snails which are known to be hosts of this ’ blood fluke have been found. Examination of more than 1,000 snails from all parts of the island, both by dissection and by the hatching uechnique, have failed to show any cecariae which are pathogenic for man. Venereal Disease. The status of venereal infection in the population is still uncertain, as a result of two widely divergent surveys. These surveys revealed $ per cent positive Kahns in one grouf of 100 persons and 30 per cent positive Kahns in s second group of similar size.