DAAM1 Antibody Cat. No.: 14-704

DAAM1 Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse, Rat

Recombinant fusion containing a sequence corresponding to amino acids IMMUNOGEN: 769-1068 of human DAAM1 (NP_001257449.1).

TESTED APPLICATIONS: WB

APPLICATIONS: WB: ,1:500 - 1:2000

POSITIVE CONTROL: 1) U-87MG

2) HepG2

3) Mouse heart

4) Mouse brain

5) Mouse liver

6) Rat heart

PREDICTED MOLECULAR Observed: 123kDa WEIGHT:

Properties

September 26, 2021 1 https://www.prosci-inc.com/daam1-antibody-14-704.html PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: DAAM1

ALTERNATE NAMES: DAAM1, FLJ41657, KIAA0666

GENE ID: 23002

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

Cell motility, adhesion, cytokinesis, and other functions of the are mediated by reorganization of the and several formin homology (FH) have been associated with these processes. The protein encoded by this contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during BACKGROUND: development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct proteins.

ANTIBODIES FOR RESEARCH USE ONLY.

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September 26, 2021 2 https://www.prosci-inc.com/daam1-antibody-14-704.html