DAAM1 Antibody Cat. No.: 14-704
DAAM1 Antibody
Specifications
HOST SPECIES: Rabbit
SPECIES REACTIVITY: Human, Mouse, Rat
Recombinant fusion protein containing a sequence corresponding to amino acids IMMUNOGEN: 769-1068 of human DAAM1 (NP_001257449.1).
TESTED APPLICATIONS: WB
APPLICATIONS: WB: ,1:500 - 1:2000
POSITIVE CONTROL: 1) U-87MG
2) HepG2
3) Mouse heart
4) Mouse brain
5) Mouse liver
6) Rat heart
PREDICTED MOLECULAR Observed: 123kDa WEIGHT:
Properties
September 26, 2021 1 https://www.prosci-inc.com/daam1-antibody-14-704.html PURIFICATION: Affinity purification
CLONALITY: Polyclonal
ISOTYPE: IgG
CONJUGATE: Unconjugated
PHYSICAL STATE: Liquid
BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.
Additional Info
OFFICIAL SYMBOL: DAAM1
ALTERNATE NAMES: DAAM1, FLJ41657, KIAA0666
GENE ID: 23002
USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background and References
Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during BACKGROUND: development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct proteins.
ANTIBODIES FOR RESEARCH USE ONLY.
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September 26, 2021 2 https://www.prosci-inc.com/daam1-antibody-14-704.html