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Rabbit Anti-NHP2L1/FITC Conjugated antibody

SL19236R-FITC

Product Name: Anti-NHP2L1/FITC Chinese Name: FITC标记的NHP2核糖核蛋白样蛋白1抗体 [U4/U6.U5] tri snRNP; 15.5 kD RNA binding ; High mobility group like nuclear Alias: protein 2 homolog 1; hSNU13; NHP2 non histone protein 2 like 1 (S. cerevisiae); NHP2L 1; NHP2L1; NH2L1_HUMAN; NHPX; OTK27; SNU13. Organism Species: Rabbit Clonality: Polyclonal React Species: ,Mouse,Dog,Cow,Sheep, ICC=1:50-200IF=1:50-200 Applications: not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. Molecular weight: 14kDa Form: Lyophilized or Liquid Concentration: 1mg/ml immunogen: KLH conjugated synthetic peptide derived from human NHP2L1 Lsotype: IgG Purification: affinity purified by Protein A Storage Buffer: 0.01Mwww.sunlongbiotech.com TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year Storage: when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. background: Originally named because of its sequence similarity to the NHP2 (non-histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri-snRNP. It binds to the 5' stem-loop of Product Detail: U4 snRNA. Two transcript variants encoding the same protein have been found for this . [provided by RefSeq, Jul 2008]

Function: Originally named because of its sequence similarity to the Saccharomyces cerevisiae NHP2 (non histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri snRNP. It binds to the 5' stem loop of U4 snRNA. Two transcript variants encoding the same protein have been found for this gene.

Subunit: Component of the U4/U6-U5 tri-snRNP complex composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8, PRPF31, SNRNP200, TXNL4A, WDR57, SNRNP40, DDX23, CD2BP2, PPIH, NHP2L1, EFTUD2, SART1 and USP39. Interacts with RAD17 and PRPF31.

Subcellular Location: Nucleus ?nucleolus. Note: Concentrated in the dense fibrillar component of the nucleolus.

Tissue Specificity: Ubiquitous.

Similarity: Belongs to the ribosomal protein L7Ae family.

Database links:

Entrez Gene: 4809 Human

Entrez Gene: 321114 Zebrafish

Omim: 601304 Human

SwissProt: P55769 Human

Unigene: 182255 Human www.sunlongbiotech.com

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.