Scientific Symposium Jaarbeurs, Utrecht

Program

Monday, Oct 29th, 2018, Chairman: Prof. Dr. Rob Pieters

09.00-09.45h Coffee and registration

09.45-10.00h Diana Monissen Welcome

10.00-11.00h Emmanuelle Charpentier CRISPR Cas9: a genome engineering technology that revolutionises life sciences and medicine

11.00-11.30h Coffee break

11.30-12.00h Charles Mullighan Genetic drivers of treatment failure in ALL

12.00-12.30h Gilles Vassal Accelerating therapeutic innovation for children and adolescents with cancer

12.30-13.30h Lunch

13.30-14.00h Lilian Sung Creating evidence-based clinical practice guidelines: prevention of fatigue and management of Clostridium difficile infection in pediatric cancer as examples

14.00-14.30h Ali Erturk Transparent mice reveal cancer metastasis and drug targeting at single-cell level

14.30-14.45h Villa Joep

14.45-15.30h Coffee break

15.30-16.00h Richard Gilbertson Mapping the origins of Paediatric and Adult Cancers

16.00-16.30h Angelika Eggert Systems Medicine Approaches in Neuroblastoma

16.30h Drinks

19.00-22.00h Dinner and tour in the Princess Máxima Center

www.princessmaximacenter.com

Page(s) 2 of 2

Tuesday, Oct 30th, 2018 Chairman: Prof. Dr. Hans Clevers

08.30-09.00h Coffee and registration

09.00-09.30h James Downing St. Jude as leading example of a comprehensive childhood cancer center

09.30-10.00h Cynthia Gerhardt New Directions for Psychosocial Research in Pediatric Oncology

10.00-10.30h Terry Fry Extending CAR T cell therapy beyond DC19 and B cell malignancies

10.30-11.00h Coffee break

11.00-11.30h Sjaak Neefjes The new biology of anthracycline drugs and how to improve these

11.30-12.00h Poul Sorensen Translational control of the cellular stress response in pediatric high-risk tumors

12.00-13.00h Lunch

13.00-13.20h Tom Voute Award / speaker 1

13.20-13.40h Tom Voute Award / speaker 2

13.40-14.00h Tom Voute Award / speaker 3

14.00-14.20h Tom Voute Award / speaker 4

14.20-15.00h Coffee break

15.00-15.30h Kathy Pritchard-Jones Measuring quality and outcomes in paediatric oncology – what can we learn?

15.30-16.00h Stephan Pfister The underappreciated role of hereditary predisposition in childhood (brain) tumors

16.00-17.00h Robert Weinberg How carcinoma cells acquire aggressive traits

17.00-17.10h Winner of the Tom Voute Award

17.10-17.15h Hans Clevers Closure

17.15-18.30h Drinks