Anti-PIR monoclonal , clone FQS22487 (DCABH-5789) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Rabbit monoclonal to Pirin

Antigen Description Possible transcriptional coregulator. May contribute to the regulation of cellular processes via its interaction with BCL3. May be required for efficient terminal myeloid maturation of hematopoietic cells. May play a role in the regulation of cell migration. May promote apoptosis when overexpressed. Has quercetin 2,3-dioxygenase activity (in vitro).

Immunogen Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human Pirin aa 200 to the C-terminus (Cysteine residue). The exact sequence is proprietary.Database link: O00625

Isotype IgG

Source/Host Rabbit

Species Reactivity Mouse, Rat, Human

Clone FQS22487

Purity Tissue culture supernatant

Conjugate Unconjugated

Applications WB

Positive Control MCF-7, HeLa and HepG2 cell lysates.

Format Liquid

Size 100 μl

Buffer pH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 49% PBS, 50% Glycerol, 0.05% BSA

Preservative 0.01% Sodium Azide

Storage 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved INFORMATION

Gene Name PIR pirin (iron-binding nuclear ) [ Homo sapiens ]

Official Symbol PIR

Synonyms PIR; pirin (iron-binding nuclear protein); pirin; probable quercetinase; probable quercetin 2,3- dioxygenase PIR;

Entrez Gene ID 8544

Protein Refseq NP_003653

UniProt ID A0A024RBX6

Chromosome Location Xp22.31

Function metal ion binding; oxidoreductase activity; protein binding; quercetin 2,3-dioxygenase activity; transcription cofactor activity;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved