Gordana CV June 2018
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Neurogenic Decisions Require a Cell Cycle Independent Function of The
RESEARCH ARTICLE Neurogenic decisions require a cell cycle independent function of the CDC25B phosphatase Fre´ de´ ric Bonnet1†, Angie Molina1†, Me´ lanie Roussat1, Manon Azais2, Sophie Bel-Vialar1, Jacques Gautrais2, Fabienne Pituello1*, Eric Agius1* 1Centre de Biologie du De´veloppement, Centre de Biologie Inte´grative, Universite´ de Toulouse, CNRS, UPS, Toulouse, France; 2Centre de Recherches sur la Cognition Animale, Centre de Biologie Inte´grative., Universite´ de Toulouse, CNRS, UPS, Toulouse, France Abstract A fundamental issue in developmental biology and in organ homeostasis is understanding the molecular mechanisms governing the balance between stem cell maintenance and differentiation into a specific lineage. Accumulating data suggest that cell cycle dynamics play a major role in the regulation of this balance. Here we show that the G2/M cell cycle regulator CDC25B phosphatase is required in mammals to finely tune neuronal production in the neural tube. We show that in chick neural progenitors, CDC25B activity favors fast nuclei departure from the apical surface in early G1, stimulates neurogenic divisions and promotes neuronal differentiation. We design a mathematical model showing that within a limited period of time, cell cycle length modifications cannot account for changes in the ratio of the mode of division. Using a CDC25B point mutation that cannot interact with CDK, we show that part of CDC25B activity is independent *For correspondence: of its action on the cell cycle. [email protected] (FP); [email protected] (EA) †These authors contributed equally to this work Introduction In multicellular organisms, managing the development, homeostasis and regeneration of tissues Competing interests: The requires the tight control of self-renewal and differentiation of stem/progenitor cells. -
2013 Annual Meeting
2013 ANNU 2013 BMES ANNUAL New Mobile App MEETING TM GO TO EITHER THE APPLE OR ANDROID A BIOMEDICAL ENGINEERING SOCIETY STORE AND SEARCH FOR: L MEETING Advancing Human Health and Well BeingTM Conference 411 > Download the free app > Select BMES2013 from the list of available 2013 ANNUAL MEETING meetings • Browse the program September 25–28, 2013 by date or session type • Search keywords Washington State • Search author list Convention Center • Add presentations to a custom itinerary Seattle, Washington • Click a link to show where a presentation is on a map of the convention center BIOMEDICAL ENGINEERING SOCIETY Advancing Human Health and Well Being 8201 Corporate Drive. Suite 1125 Landover, MD 20785-2224 Phone: 301-459-1999 Fax: 301-459-2444 Web: www.bmes.org BMES 2013 BMES Officers BIOMEDICAL ENGINEERING SOCIETY Advancing Human Health and Well Being President Gilda Barabino, PhD 8201 Corporate Drive, Suite 1125 The City College of New York Landover, MD 20785-2224 Phone: 301-459-1999 Immediate Past President Fax: 301-459-2444 Web: www.bmes.org Richard E. Waugh, PhD University of Rochester BMES Staff Secretary Edward L. Schilling, III David A. Vorp, PhD Executive Director University of Pittsburgh Doug Beizer Treasurer Communications Director Jennifer West, PhD Jennifer Edwards Duke University Membership Director Valerie A. Kolmaister Publications Board Chair Operations and Finance Director Frank C. P. Yin, MD, PhD Michele Surricchio, MPH, CHES Washington University in St. Louis Education Director Finance Committee Chair Debra Tucker, CMP -
Resume of Kejin Hu
CURRIULUM VITAE Of Kejin Hu PERSONAL INFORMATION Name: Kejin HU Visa status: USA citizen Language(s): English, Chinese Home city: Vestavia Hills, AL, 35226 RANK/TITLE, Assistant Professor Department: Biochemistry and Molecular Genetics Division: UAB Stem Cell Institute Business Address: SHEL 705, 1825 University Boulevard, Birmingham, AL, 35294 Phone: 205-934-4700 (office); 205-876-8693 (home); 205-703-6688 (cell) Fax: 205-975-3335 MEMBERSHIP: ISSCR (international Society for Stem Cell Research), since 2011 Member of Genetics Society of America (GSA, since 2006) EDUCATIONS June, 1999 to May, 2003, PhD, in marine molecular biology at the Department of Zoology, The University of Hong Kong, Hong Kong, China. July, 1995-October, 1997, MPhil, in fungal biochemistry/microbiology in the Hong Kong Polytechnic University. September, 1981-July, 1985, BSc in botany/agronomy at The Central China (Huazhong) Agricultural University, Wuhan, China. TEACHING EXPERIENCE: Advanced Stem Cell/Regenerative medicine, GBSC 709, Since 2014 SCIENTIFIC ACTIVITIES Ad hoc reviewer for the following journals: 1) Stem Cells; 2) Stem Cells and Development; 3) Stem Cell International; 4) Human Immunology; 5) Molecular Biotechnology; 6) Comparative Biochemistry and Physiology; 7) Journal of Heredity; 8) Scientific Reports; 9) Cellular Reprogramming; 10) Cell and Tissue Research; 11) Science Bulletin; 12) Reproduction, Fertility and Development. 1 Grant Reviewer for 1) Medical Research Council (MRC) of the United Kingdom (remote review, 2015); 2) New York Stem Cell Science (panel meeting from 09/28-09/30, 2016); 3) UAB internal grants SCIENTIFIC/ACADEMIC EXPERIENCE 2011 to present, Assistant Professor, Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL September, 2007 to July, 2011, Research Associate in human iPSC reprogramming and human pluripotent stem cell biology, and their differentiation into blood lineage, Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI. -
Autophagy in the Endocrine Glands
A WECKMAN and others Autophagy in the endocrine 52:2 R151–R163 Review glands Autophagy in the endocrine glands Andrea Weckman, Antonio Di Ieva, Fabio Rotondo1, Luis V Syro2, Leon D Ortiz3, Kalman Kovacs1 and Michael D Cusimano Division of Neurosurgery, Department of Surgery, St Michael’s Hospital, University of Toronto, Toronto, Ontario, Canada Correspondence 1Division of Pathology, Department of Laboratory Medicine, St Michael’s Hospital, University of Toronto, Toronto, should be addressed Ontario, Canada to A Di Ieva 2Department of Neurosurgery, Hospital Pablo Tobon Uribe and Clinica Medellin, Medellin, Colombia Email 3Division of Neurooncology, Instituto de Cancerologia, Clinic Las Americas, Medellin, Colombia [email protected] Abstract Autophagy is an important cellular process involving the degradation of intracellular Key Words components. Its regulation is complex and while there are many methods available, there is " autophagy currently no single effective way of detecting and monitoring autophagy. It has several " endocrine glands cellular functions that are conserved throughout the body, as well as a variety of different " crinophagy physiological roles depending on the context of its occurrence in the body. Autophagy is also " endocrine diseases involved in the pathology of a wide range of diseases. Within the endocrine system, autophagy has both its traditional conserved functions and specific functions. In the endocrine glands, autophagy plays a critical role in controlling intracellular hormone levels. In peptide-secreting cells of glands such as the pituitary gland, crinophagy, a specific form of autophagy, targets the secretory granules to control the levels of stored hormone. In steroid-secreting cells of glands such as the testes and adrenal gland, autophagy targets the steroid-producing organelles. -
Celebration of Teaching Program
Celebration of Teaching April 16, 2021 · Zoom · 1:00-3:00pm Program WELCOME & INTRODUCTION OF DEAN RASHID BASHIR Jay Mann, Director of AE3 REMARKS Rashid Bashir, Dean KEYNOTE ADDRESS Dr. Gilda Barabino President, Olin College of Engineering COLLINS SCHOLAR REFLECTION AND RECOGNITION Chris Migotsky, Faculty Teaching Programs Coordinator & Jay Mann Eleftharia Kontou (2019-2020) & Brad Solomon (2020-2021) CELEBRATING EXCELLENCE IN ENGINEERING EDUCATION Jonathan Makela, Associate Dean & Jay Mann SIIP POSTER SESSION Rashid Bashir Dean, Grainger College of Engineering Rashid Bashir is Dean of The Grainger College of Engineering, the Grainger Distinguished Chair in Engineering and Professor of Bioengineering at the University of Illinois at Urbana-Champaign (UIUC). He received the NSF Faculty Early Career Award, the 2012 IEEE EMBS Technical Achievement Award, the Pritzker Distinguished Lectureship Award from BMES in 2018, and the 2021 American Institute for Medical and Biological Engineering Professional Impact Award. He has been involved in 3 startups that have licensed his technologies. He was part of the core founding team and co-chair of the curriculum committee for the Carle Illinois College of Medicine. His research group is interested in developing new technologies for precision and personalized medicine, and 3D bio-fabrication of cellular systems. Using bionanotechnology, BioMEMS, and lab on chip, he is working at the interface of biology and engineering from the molecular to the tissue scale, and aiming to make an impact on grand challenges in health and medicine. Dr. Gilda Barabino President, Olin College of Engineering Gilda A. Barabino is President of Olin College of Engineering, and Professor of Biomedical and Chemical Engineering. -
14Th Heinz Awards General Press Release
EMBARGOED FOR RELEASE Contacts: Jon Newman SEPTEMBER 9, 2008 (804) 788-1414 Russ Martz (412) 497-5775 Heinz Awards Honor Five Eminent Americans with 14th Annual Human Achievement Prize Trailblazers in five categories to share $1.25 million awards PITTSBURGH, September 9, 2008 – Celebrating the unbridled human spirit to change the world around us in ways great and small, in the here and now, and for generations to come, the Heinz Family Foundation today announced the recipients of the 14th annual Heinz Awards, among the largest individual achievement prizes in the world. The $250,000 awards recognize significant accomplishments in five distinct categories – the arts and humanities; the environment; human condition; public policy; and technology, the economy and employment. Each area was of particular interest to John Heinz, the late U.S. Senator for whom the awards are named. The recipients, in their respective categories, are: • Arts and Humanities: Ann Hamilton, 52, visual artist and educator, from Columbus, Ohio • Environment: Thomas FitzGerald, 53, founder and director of the Kentucky Resources Council, from Louisville, Ky. • Human Condition: Brenda Krause Eheart, Ph.D., 64, founder of Generations of Hope and Hope Meadows, from Champaign, Ill. - more - • Public Policy: Robert Greenstein, 62, founder and executive director of the Center on Budget and Policy Priorities, from Washington, D.C. • Technology, the Economy and Employment: Joseph DeRisi, Ph.D., 38, molecular biologist, researcher and inventor, from San Francisco, Calif. “If history teaches us anything,” said Teresa Heinz, chairman of the Heinz Family Foundation, “it is that civilizations advance on the backs of singular individuals whose inspiration, foresight and determination know no bounds. -
Mentoring and Advising of Black Students in Science, Engineering, and Medicine: a Workshop
Mentoring and Advising of Black Students in Science, Engineering, and Medicine: A Workshop December 7-8, 2020 Mentoring and Advising of Black Students in Science, Engineering, and Medicine: A Workshop December 7-8, 2020 https://nasem.zoom.us/j/92451902299?pwd=Um9ORmNmaS9UNmlmKzB0ZWwvbk11UT09 Day One - December 7, 2020 9:30 AM EDT Opening Remarks John L. Anderson, PhD President, National Academy of Engineering and Vice Chairman, National Research Council Cato T. Laurencin, MD, PhD Chair of the Roundtable; Albert and Wilda Van Dusen Distinguished Professor of Orthopaedic Surgery; Professor of Chemical and Biomolecular Engineering Professor of Materials Science and Engineering, University of Connecticut Randall C. Morgan, Jr., MD, MBA Co-Chair of the Mentoring and Advising Action Group; President and CEO, Cobb/NMA Health Institute; Clinical Associate Professor of Orthopedic Surgery at Florida State School of Medicine and Clinical Associate Professor in the Department of Community Medicine at the University of Connecticut Joan Y. Reede, MD, MPH, MS, MBA Co-Chair of the Mentoring and Advising Action Group; Professor of Medicine; Dean for Diversity and Community Partnership, Harvard Medical School: Professor in the Department of Social and Behavioral Sciences, Harvard TH Chan School of Public Health SESSION I : UNDERSTANDING THE CURRENT STATUS OF BLACK PROFESSIONALS IN ACADEMIA AND INDUSTRY 10:00 AM MODERATOR: L. D. Britt, MD, MPH, DSc(Hon), FACS, FCCM Chairman, Surgery Department, Eastern Virginia Medical School 1 SPEAKERS: Norma Poll-Hunter, -
Targeting Macrophages As a Candidate for Tissue Regeneration
Macrophages and Tissue Regeneration Zhang et al. Curr. Issues Mol. Biol. (2018) 29: 37-48. caister.com/cimb Snapshot: Targeting Macrophages as a Candidate for Tissue Regeneration Jing Zhang1,2,3, Yang Yang4, Zhi Yang4,5, Tian Li4,5 and Fulin Chen1,2,3* Introduction Macrophages, also known as "big eaters" due to 1Lab of Tissue Engineering, College of Life their phagocytic capacity, were first annotated by Sciences, Northwest University, 229 Taibai North Mechnikov in the late 18th century (Fraga et al., Road, Xi'an, 710069, P. R. China 2017; Tauber, 2003; Wan et al., 2017). They are a 2Provincial Key Laboratory of Biotechnology of specific mononuclear cell group abundant in almost Shaanxi, 229 Taibai North Road, Xi'an, 710069, P. every organ of higher animals. In mammals, R. China macrophages can derive from the yolk sac, fetal 3Key Laboratory of Resource Biology and liver, and bone marrow (Geissmann et al., 2010; Biotechnology in Western China Ministry of Wynn et al., 2013). Their differentiation is Education, 229 Taibai North Road, Xi'an, 710069, P. orchestrated by multiple growth factors (GFs) R. China. (Gordon, 2003; Sica et al., 2012). Tissue-resident 4College of Life Sciences, Northwest University, 229 macrophages, usually originating from the bone Taibai North Road, Xi'an, 710069, P. R. China marrow hematopoietic progenitors, has the ability of 5Department of Biomedical Engineering, The Fourth self-renewing (Geissmann et al., 2010; Jenkins et Military Medical University, 169 Changle West Road, al., 2011; Schulz et al., 2012; Davies et al., 2013). Xi'an 710032, China Generally, they are divided into two phenotypes, classically activated M1 macrophages and * Correspondence: [email protected] alternatively activated M2 macrophages, which refer to the state activated by Th1 and Th2 lymphocytes DOI: https://dx.doi.org/10.21775/cimb.029.037 or with interferon-gamma (INF-γ) and interleukin 4 (IL-4), respectively (Goerdt et al., 1999; Gordon, Abstract 2003; Sica et al., 2012). -
Improving Critical Thinking in Underserved Minority Students
THE DECADE AHEAD Lord Baltimore Hotel 20 West Baltimore Street Baltimore, Maryland 21201 10TH CONFERENCE ON UNDERSTANDING INTERVENTIONS That Broaden Participation in Science Careers THE DECADE AHEAD March 2-4, 2018 The Lord Baltimore Hotel Baltimore, Maryland Daryl E. Chubin & Anthony L. DePass, Co-chairs www.understanding-interventions.org FU N D I N G A N D S U PP O R T Understanding Interventions that Broaden Participation in Science Careers has benefited from generous support from the National Institutes of Health, the National Science Foundation, the Alfred P. Sloan Foundation, Howard Hughes Medical Institute, and Educational Testing Service, along with productive collaborations with the National Academies of Sciences, Engineering and Medicine, the American Society for Cell Biology, the American Society of Plant Biologists, American Association for the Advancement of Science, and Long Island University. In September 2013, an NIGMS T36 MARC grant from the National Institutes of Health (Grant No.1 T36 GM 102000) was awarded to Long Island University and it currently provides long- term support for the following: Organization of conferences that will provide: a) venues for dissemination of interventions research and related training; b) opportunities for researchers/practitioners to interact and collaborate; and c) a mechanism for discourse on research-based interventions’ implementation across modalities, stages, and venues. An enhanced and interactive Understanding Interventions website that will: a) facilitate linkages among members of the Understanding Interventions (UI) community; and b) feature an accessible and searchable internet-based annotated database of Interventions articles and other resources. This will expand the dissemination of broadening participation research. An online/email-based publication that distills and disseminates research findings, development opportunities, and general announcements to provide an additional platform for growth of the Understanding Interventions community. -
Activation of Stem Cells in Hepatic Diseases
Edinburgh Research Explorer Activation of stem cells in hepatic diseases Citation for published version: Bird, TG, Lorenzini, S & Forbes, SJ 2008, 'Activation of stem cells in hepatic diseases', Cell and tissue research, vol. 331, no. 1, pp. 283-300. https://doi.org/10.1007/s00441-007-0542-z Digital Object Identifier (DOI): 10.1007/s00441-007-0542-z Link: Link to publication record in Edinburgh Research Explorer Document Version: Peer reviewed version Published In: Cell and tissue research General rights Copyright for the publications made accessible via the Edinburgh Research Explorer is retained by the author(s) and / or other copyright owners and it is a condition of accessing these publications that users recognise and abide by the legal requirements associated with these rights. Take down policy The University of Edinburgh has made every reasonable effort to ensure that Edinburgh Research Explorer content complies with UK legislation. If you believe that the public display of this file breaches copyright please contact [email protected] providing details, and we will remove access to the work immediately and investigate your claim. Download date: 06. Oct. 2021 Europe PMC Funders Group Author Manuscript Cell Tissue Res. Author manuscript; available in PMC 2011 February 06. Published in final edited form as: Cell Tissue Res. 2008 January ; 331(1): 283–300. doi:10.1007/s00441-007-0542-z. Europe PMC Funders Author Manuscripts Activation of stem cells in hepatic diseases T. G. Bird, S. Lorenzini, and S. J. Forbes MRC/University of Edinburgh Centre for Inflammation Research, The Queen’s Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK Abstract The liver has enormous regenerative capacity. -
Efactor October 2009
October 2009 NIEHS Spotlight Science Notebook Council Meeting Highlights NIEHS Director Gives Mission Accomplishments Distinguished Lecture Throughout the September 15–16 NIEHS and National Toxicology meeting of the National Advisory Program (NTP) Director Linda Environmental Health Sciences Birnbaum, Ph.D., D.A.B.T., A.T.S., Council (NAEHSC) at NIEHS, the presented the first seminar of the discussions were upbeat. ...read more 2009 – 2010 NIEHS Distinguished Lecture Series on September 8 titled “Halogenated Flame Retardants: Does the Benefit Justify the Risk?” ...read more Fellows Recognized at Regional Showcase in Cincinnati NIEHS Microarray Group The University of Cincinnati (UC) Hosts Genomics Day Center for Environmental Genetics (CEG) joined with other NIEHS- NIEHS Genomics Day, held on supported training programs, Centers September 1, offered scientists at and Superfund Research Programs to celebrate the first NIEHS and visitors an afternoon of Environmental Health Sciences Regional Showcase of talks by investigators and trainees, Fellows on September 18 at UC. ...read more a poster session, and an opportunity to learn more about the NIEHS Microarray Laboratory. ...read more 2009 ONES Awardees Named Genome-Wide Association NIEHS announced the selection of six early-stage tenure-track Study Focuses on Asthma investigators as 2009 Outstanding in Children New Environmental Scientist (ONES) A new genome-wide association awardees. ....read more study (GWAS) published August 28 in PLoS Genetics identified the chromosome 9q21.31 region -
Bethany Catalogue 2008-2009
Bethany Catalogue 2008-2009 Table of Contents College Calendar . 2 Bethany Profile . 3 Admission to the College . 4 Expenses, Aid . 6 Academic Programs . 9 Academic Procedures . 9 Scholarships, Recognition Awards . 22 Student Life . 29 College Facilities . 32 Academic Programs . 34 Biology . 34 Communication . 37 Economics & Business . 4 Education . 45 Fine and Performing Arts . 5 First Year Experience . 59 Fundamental Studies . 62 General Science . 62 History and Political Science . 64 Interdisciplinary Studies . 69 Literature and Language . 72 Mathematics and Computer Science . 82 Physical Education and Sports Studies . 88 Physical Science . 92 Psychology . 97 Religious Studies and Philosophy . 00 Social Science . 06 Social Work . 07 Directories . 111 Index . 22 Bethany e-mail address: [email protected] Bethany on the World Wide Web: www.bethanywv.edu Bethany College Bethany, West Virginia 26032 304-829-7000 1-800-922-7611 College Calendar2008-2009 The Bethany calendar includes two 5-week semesters and a three-week January Term . The fall semester begins in late August and ends before Christmas . The spring semester begins in late-January and ends in mid-May . Summer independent study options are offered . FALL SEMESTER 2008 SPRING SEMESTER 2009 August January 22-24 Friday-Sunday Orientation and evaluation for new students 25 Sunday Final Registration for all students 22 Friday Freshman Convocation 26 Monday First day of classes for all students 24 Sunday Final Registration 30 Friday Last day for adjustment of schedules 25 Monday