Anti-LGI1 Monoclonal Antibody, Clone FQS0195 (DCABH-3306) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-LGI1 monoclonal antibody, clone FQS0195 (DCABH-3306) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Rabbit monoclonal to Lgi1

Antigen Description Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA- type glutamate receptors (By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.

Immunogen Synthetic peptide corresponding to residues in Human Lgi1 (UniProt ID: O95970)

Isotype IgG

Source/Host Rabbit

Species Reactivity Mouse, Rat, Human

Clone FQS0195

Purity Tissue culture supernatant

Conjugate Unconjugated

Applications IP, WB, IHC-P

Positive Control HeLa and U87-MG lysates; Human brain tissue.

Format Liquid

Size 100 μl

Buffer Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA

Preservative 0.01% Sodium Azide

Storage store at -20°C. Avoid freeze / thaw cycles.

Ship Shipped at 4°C.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Gene Name LGI1 leucine-rich, glioma inactivated 1 [ Homo sapiens ]

Official Symbol LGI1

Synonyms LGI1; leucine-rich, glioma inactivated 1; epilepsy, partial , EPT; leucine-rich glioma-inactivated protein 1; EPITEMPIN; ETL1; IB1099; epitempin-1; EPT; ADLTE; ADPAEF;

Entrez Gene ID 9211

Protein Refseq NP_005088

UniProt ID O95970

Chromosome Location 10q24

Function protein binding; receptor binding; NOT receptor binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]