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United States Court of Appeals for the Federal Circuit ______ APPENDIX VOLUME VI (Pages A4530-A7340) No. 2010-1406 United States Court of Appeals for the Federal Circuit ________________ THE ASSOCIATION FOR MOLECULAR PATHOLOGY, THE AMERICAN COLLEGE OF MEDICAL GENETICS, THE AMERICAN SOCIETY FOR CLINICAL PATHOLOGY, THE COLLEGE OF AMERICAN PATHOLOGISTS, HAIG KAZAZIAN, MD, ARUPA GANGULY, PHD, WENDY CHUNG, MD, PHD, HARRY OSTRER, MD, DAVID LEDBETTER, PHD, STEPHEN WARREN, PHD, ELLEN MATLOFF, M.S., ELSA REICH, M.S., BREAST CANCER ACTION, BOSTON WOMEN’S HEALTH BOOK COLLECTIVE, LISBETH CERIANI, RUNI LIMARY, GENAE GIRARD, PATRICE FORTUNE, VICKY THOMASON, and KATHLEEN RAKER, Plaintiffs-Appellees, v. UNITED STATES PATENT AND TRADEMARK OFFICE, Defendant, and MYRIAD GENETICS, INC., Defendant-Appellant, (caption continued on inside cover) Appeal From The United States District Court For The Southern District of New York In Case No. 09-CV-4515, Senior Judge Robert W. Sweet APPENDIX VOLUME VI (Pages A4530-A7340) BRIAN M. POISSANT ISRAEL SASHA MAYERGOYZ GREGORY A. CASTANIAS LAURA A. CORUZZI JONES DAY JONES DAY EILEEN FALVEY 77 West Wacker Drive 51 Louisiana Avenue, N.W. JONES DAY Chicago, IL 60601 Washington, D.C. 20001 222 East 41st Street (312) 782-3939 (202) 879-3939 New York, NY 10017 (212) 326-3939 (additional counsel listed on inside cover) Attorneys for Defendants-Appellants Myriad Genetics, Lorris Betz, Roger Boyer, Jack Brittain, Arnold B. Combe, Raymond Gesteland, James U. Jensen, John Kendall Morris, Thomas Parks, David W. Pershing, and Michael K. Young and LORRIS BETZ, ROGER BOYER, JACK BRITTAIN, ARNOLD B. COMBE, RAYMOND GESTELAND, JAMES U. JENSEN, JOHN KENDALL MORRIS, THOMAS PARKS, DAVID W. PERSHING, and MICHAEL K. YOUNG, in their official capacity as Directors of the University of Utah Research Foundation, Defendants-Appellants. Of counsel for Defendant-Appellant Myriad Genetics, Inc.: JAY Z. ZHANG BENJAMIN G. JACKSON MYRIAD GENETICS, INC. 320 Wakara Way Salt Lake City, UT 84108 (801) 883-3328 TABLE OF CONTENTS VOLUME I JUDGMENTS AND ORDERS APPEALED FROM Opinion Denying Defendant’s Motion To Dismiss of November 1, 2009 ............A1 Amended Opinion Denying Defendant’s Motion for Summary Judgment and Order of April 2, 2010 .........................................................................A89 Judgment of April 19, 2010 ...............................................................................A248 PATENTS-IN-SUIT U.S. Patent No. 5,693,473...................................................................................A259 U.S. Patent No. 5,709,999...................................................................................A362 VOLUME II U.S. Patent No. 5,710,001...................................................................................A469 U.S. Patent No. 5,747,282...................................................................................A569 U.S. Patent No. 5,753,441...................................................................................A673 U.S. Patent No. 5,837,492...................................................................................A775 U.S. Patent No. 6,033,857...................................................................................A870 VOLUME III PACER DOCKET SHEET .............................................................................A968 PLEADINGS AND OTHER PAPERS Complaint filed May 12, 2009..........................................................................A1034 Defendant United States Patent and Trademark Office’s Memorandum of Law in Support of Motion to Dismiss and Notice ............................A1101 Defendants Myriad Genetics et al. Memorandum of Law in Support of Defendant’s Motion to Dismiss and Notice ..........................................A1120 Declaration of Barry R. Satine..........................................................................A1142 Exhibit 1 of Ravicher Declaration — Letter to B. Satine.................................A1256 Declaration of Madhuri Hegde, Ph.D. ..............................................................A1282 Declaration of Wendy Chung, MD, Ph.D.........................................................A1302 Declaration of Roger Hubbard, Ph.D................................................................A1342 Declaration of Jeffrey A. Kant, MD, Ph.D. ......................................................A1357 Cover page and first page of Exhibit 2 of Ganguly Declaration ......................A1436 Declaration of Harry Ostrer, M.D.....................................................................A1462 Declaration of David H. Ledbetter, Ph.D. ........................................................A1505 Declaration of Ellen T. Matloff, M.S................................................................A1550 Declaration of Lisbeth Ceriani..........................................................................A1593 Declaration of Runi Limary ..............................................................................A1597 Declaration of Genae Girard.............................................................................A1601 Declaration of Patrice Fortune..........................................................................A1605 Declaration of Vicky Thomason.......................................................................A1609 Declaration of Kathleen Raker..........................................................................A1613 Plaintiffs’ Notice and Memorandum of Law in Support of Motion for Summary Judgment; Plaintiffs’ Rule 56.1 Statement of Material Facts ................A1634 Declaration of Sir John E. Sulston, Ph.D..........................................................A2439 Declaration of Wayne W. Grody, M.D., Ph.D..................................................A2464 Declaration of Debra G.B. Leonard, M.D., Ph.D. ...........................................A2555 Declaration of Christopher E. Mason ...............................................................A2601 - 2 - Declaration of Myles W. Jackson .....................................................................A2614 Declaration of Elizabeth Swisher, M.D. ...........................................................A2642 Declaration of Mildred Cho, Ph.D....................................................................A2670 Declaration of Shobita Parthasarathy, Ph.D. ....................................................A2697 Declaration of Dr. Susan M. Love....................................................................A2725 Declaration of Mark Sobel................................................................................A2750 Declaration of Madhuri Hegde, Ph.D. ..............................................................A2752 Declaration of Michael S. Watson, Ph.D..........................................................A2769 Declaration of Wendy Chung, MD, Ph.D.........................................................A2772 Declaration of John R. Ball...............................................................................A2809 Declaration of Roger Hubbard, Ph.D................................................................A2812 Declaration of John Scott..................................................................................A2824 Declaration of Jeffrey A. Kant, MD, Ph.D. ......................................................A2827 Declaration of Haig H. Kazazian, Jr., M.D.......................................................A2848 Declaration of Arupa Ganguly, Ph.D................................................................A2887 Exhibit 1 of Ganguly Declaration — Letter from Myriad to Kazazian............A2907 Declaration of Harry Ostrer, M.D.....................................................................A2932 Exhibit 1 of Ostrer Declaration — Letter from Myriad to Kazazian ...............A2964 Declaration of David. H. Ledbetter, Ph.D. .......................................................A2975 Declaration of Ellen T. Matloff, M.S................................................................A3020 Declaration of Elsa W. Reich, M.S...................................................................A3034 Declaration of Barbara A. Brenner ...................................................................A3054 Declaration of Lisbeth Ceriani..........................................................................A3063 - 3 - Declaration of Runi Limary ..............................................................................A3067 Declaration of Genae Girard.............................................................................A3071 VOLUME IV Declaration of Patrice Fortune..........................................................................A3075 Declaration of Vicky Thomason.......................................................................A3079 Declaration of Kathleen Raker..........................................................................A3083 Brief for Amici Curiae, March of Dimes Foundation, et al..............................A3099 Brief for Amici Curiae, American Medical Association, et al. ........................A3141 Brief for Amici Curiae, National Women’s Health Network, et al..................A3188 Brief for Amici Curiae, The International Center for Technology Assessment, et al. ...............................................................A3240 Exhibit 1 of Satine Declaration — Response to Letter from D. Ravicher .......A3364 Myriad Defendants’ Notice and Memorandum of Law (1) In Support of Their Motion for Summary Judgment and (2) In Opposition to Plaintiffs' Motion for Summary Judgment;
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