CSNK1D Antibody Cat. No.: 62-884
CSNK1D Antibody
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. BC = breast carcinoma; HC = hepatocarcinoma.
Specifications
HOST SPECIES: Rabbit
SPECIES REACTIVITY: Human
HOMOLOGY: Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
This CSNK1D antibody is generated from rabbits immunized with a KLH conjugated IMMUNOGEN: synthetic peptide between 321-352 amino acids from the C-terminal region of human CSNK1D.
TESTED APPLICATIONS: IHC-P, WB
For WB starting dilution is: 1:1000 APPLICATIONS: For IHC-P starting dilution is: 1:50~100
September 28, 2021 1 https://www.prosci-inc.com/csnk1d-antibody-62-884.html PREDICTED MOLECULAR 47 kDa WEIGHT:
Properties
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by PURIFICATION: dialysis
CLONALITY: Polyclonal
ISOTYPE: Rabbit Ig
CONJUGATE: Unconjugated
PHYSICAL STATE: Liquid
BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
CONCENTRATION: batch dependent
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
OFFICIAL SYMBOL: CSNK1D
ALTERNATE NAMES: Casein kinase I isoform delta, CKI-delta, CKId, Tau-protein kinase CSNK1D, CSNK1D, HCKID
ACCESSION NO.: P48730
PROTEIN GI NO.: 27923980
GENE ID: 1453
USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background and References
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more BACKGROUND: than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The casein kinase 1 (CK1) group consists of 12 kinases including CK1, TTBK (tau tubulin kinase), and VRK (vaccinia-related kinase) families. The receptor guanylate cyclase (RGC) group consists of 5 kinases similar in domain sequence to TKs (ANP, CYG).
REFERENCES: 1) Sillibourne, J.E., et al., J. Mol. Biol. 322(4):785-797 (2002).
September 28, 2021 2 https://www.prosci-inc.com/csnk1d-antibody-62-884.html 2) Rivers, A., et al., J. Biol. Chem. 273(26):15980-15984 (1998).
3) Kusuda, J., et al., Genomics 32(1):140-143 (1996).
4) Fish, K.J., et al., J. Biol. Chem. 270(25):14875-14883 (1995).
ANTIBODIES FOR RESEARCH USE ONLY.
For additional information, visit ProSci's Terms & Conditions Page.
September 28, 2021 3 https://www.prosci-inc.com/csnk1d-antibody-62-884.html