CSNK1D Antibody Cat. No.: 62-884

CSNK1D Antibody

Formalin-fixed and paraffin-embedded human tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. BC = breast carcinoma; HC = hepatocarcinoma.

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

HOMOLOGY: Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

This CSNK1D antibody is generated from rabbits immunized with a KLH conjugated IMMUNOGEN: synthetic peptide between 321-352 amino acids from the C-terminal region of human CSNK1D.

TESTED APPLICATIONS: IHC-P, WB

For WB starting dilution is: 1:1000 APPLICATIONS: For IHC-P starting dilution is: 1:50~100

September 28, 2021 1 https://www.prosci-inc.com/csnk1d-antibody-62-884.html PREDICTED MOLECULAR 47 kDa WEIGHT:

Properties

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by PURIFICATION: dialysis

CLONALITY: Polyclonal

ISOTYPE: Rabbit Ig

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.

CONCENTRATION: batch dependent

Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Info

OFFICIAL SYMBOL: CSNK1D

ALTERNATE NAMES: Casein I isoform delta, CKI-delta, CKId, Tau- kinase CSNK1D, CSNK1D, HCKID

ACCESSION NO.: P48730

PROTEIN GI NO.: 27923980

GENE ID: 1453

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

Protein are that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more BACKGROUND: than 500 products, the protein kinase family is one of the largest families of in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The (CK1) group consists of 12 kinases including CK1, TTBK (tau tubulin kinase), and VRK (vaccinia-related kinase) families. The receptor guanylate cyclase (RGC) group consists of 5 kinases similar in domain sequence to TKs (ANP, CYG).

REFERENCES: 1) Sillibourne, J.E., et al., J. Mol. Biol. 322(4):785-797 (2002).

September 28, 2021 2 https://www.prosci-inc.com/csnk1d-antibody-62-884.html 2) Rivers, A., et al., J. Biol. Chem. 273(26):15980-15984 (1998).

3) Kusuda, J., et al., Genomics 32(1):140-143 (1996).

4) Fish, K.J., et al., J. Biol. Chem. 270(25):14875-14883 (1995).

ANTIBODIES FOR RESEARCH USE ONLY.

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