Date Prepared 4/21/2016 Curriculum Vitae Linda Moy, M.D. New York

Date prepared 4/21/2016

Curriculum Vitae

Linda Moy, M.D. New York University Langone Medical Center New York University Cancer Institute Department of Radiology 160 East 34th Street New York, NY 10016 Phone: (212) 731-5353; fax: (212) 731-5554 Email: [email protected]

Education Year Degree Field Institution 1986 Diploma Bronx High School of Science 1990 B.A. Biology and Society Cornell University 1994 M.D. Medicine State University of New York, Health Science Center at Brooklyn

Postdoctoral Training Year Specialty Director/Mentor Institution 1995 Internal in Medicine Michael Bruno, MD Lenox Hill Hospital 1995 - 1999 Resident, Radiology Steven Amis, MD Albert Einstein/ Montefiore Medical Center 1999 - 2000 Fellowship, Breast Imaging Daniel Kopans, MD Massachusetts General Hospital

Licensure and Certification 1994 Diplomate National Board of Medical Examiners 1995 New York State Medical License (#200816), active 1999 Diplomate American Board of Radiology 1999 Massachusetts Medical License, inactive

Academic Appointments 1999 - 2000 Clinical Fellow in Radiology Harvard Medical School 2000 - 2001 Instructor of Radiology Harvard Medical School 2002 - 2013 Assistant Professor of Radiology New York University School of Medicine 2014 - present Associate Professor of Radiology New York University School of Medicine

Hospital Appointments 2000 - 2001 Attending Radiologist Massachusetts General Hospital 2002 - present Attending Radiologist New York University Langone Medical Center 2002 - present Attending Radiologist Bellevue Hospital 2002 - present Attending Radiologist Gouverneur Health Care Services

Other Professional Positions and Visiting Appointments None

Awards and Honors 1990 Cum Laude 1990 -1994 State University of New York: Merit-based scholarship for four years 1994 American Medical Women's Association, The Janet M. Glasgow Memorial Achievement Citations, Top 10% of the graduating female medical students for the Class of 1994 1996 RSNA/ARRS/AUR Introduction to Research Resident Award 1999 RSNA Roentgen Fellow Research Award 1999 Massachusetts General Hospital – Fellow of the Year Award 1999 AAWR Research and Education Foundation Member-In-Training Award for RSNA December 2000 2000 New England Roentgen Society: Fellow of the Year Award 2012 Distinguished Reviewer - Journal of Magnetic Resonance in Imaging 2013 Fellow - Society of Breast Imaging 2014 NYU-HHC CTSI Mentor Development Program

Major Committee Assignments National 2009 NIH Study Section Reviewer: Reviewer for NIH: 93.701 – Trans-NIH Recovery Act Research Support Challenge grant reviewer, ad hoc reviewer 2009 NIH Study Section Reviewer: Scientific Review Group: ZRG1 SBIB-V 58 R, RFA OD- 09-003 Challenging Grants Panel 23, ad hoc reviewer 2009 - 2014 NIH Study Section Reviewer (R21: Quick Trials on Imaging & Imaged Guided Interventions) Special Emphasis Panel/Scientific Review Group ZRG1 SBIB-V (56), permanent reviewer 2010 - present Susan Komen Foundation Grant Scientific Reviewer Susan G. Komen for the Cure Research Programs – Post-baccalaureate Training Disparities Research, ad hoc reviewer 2010 - present Susan Komen Foundation Grant Scientific Reviewer Susan G. Komen for the Cure Research Programs - Prevention/Early Detection 2010 - present Susan Komen Foundation Grant Scientific Reviewer, ad hoc reviewer Susan G. Komen for the Cure Research Programs - Translational 1-Diagnostic and Therapeutic Targets, ad hoc reviewer 2014 - present DOD Breast Cancer Research Program Scientific Reviewer – IDEA Expansion award and Breakthrough Award, permanent reviewer 2014 - present ECOG-ACRIN Breast Committee 2014 - present NIH Study Section Reviewer (R01: Early Phase Clinical Trials in Imaging and Imaging- guided Intervention) Special Emphasis Panel/Scientific Review Group ZRG1 SBIB-F56R, permanent reviewer

Regional 2013 - present Alternate Delegate - New York State Radiologic Society 2016 Breast Imaging Committee of the New York State Radiological Society

Medical School and Hospital Committee 1999 - 2001 Member of the Mammography Quality Standards Act (MQSA) Committee Department of Radiology, Massachusetts General Hospital 2002 - 2008 Jonas Salk Society - Masters Scholars Mentoring Program Mentor medical students during the first two years.

New York University School of Medicine 2003 - 2010 Education Committee, Radiology Residency Program New York University School of Medicine 2007 - present NYU Breast Cancer Risk Assessment Program New York University Cancer Institute 2008 - present Protocol Review and Monitoring Committee New York University Cancer Institute 2010 - present Breast Cancer Screening and Prevention Program New York University Cancer Institute 2010 - present Institutional Review Board Committee New York University School of Medicine

Memberships, Offices, and Committee Assignments in Professional Societies Membership 1995 - present Member, Radiology Society of North America 1995 - present Member, American Roentgen Ray Society 1995 - present Member, New York Roentgen Society, 1995 - present Member, American College of Radiology 1999 - present Member, Society of Breast Imaging 2002 - 2014 Member, American Society of Breast Disease 2003 - present Member, International Society of Magnetic Resonance in Medicine

Committee Assignments 2005 - present American Journal of Roentgenology - Women’s Imaging Education Committee 2005 - 2011 American Society of Breast Disease - Regional Symposia Planning Committee 2005 - 2011 American Society of Breast Disease - Education Program Committee 2011 - 2014 American Society of Breast Disease - Consensus Committee 2011 - present American Roentgen Ray Society - CME Review Subcommittee 2012 - present American College of Radiology Committee on Screening and Emerging Technology – Breast Imaging 2012 - present American Roentgen Ray Society - Scientific Program Subcommittee 2013 - present American College of Radiology Joint Committee on Breast Imaging for the Appropriateness Criteria and Guidelines and Standards 2013 - present International Society for Magnetic Resonance in Medicine - Annual Meeting Program Committee 2013 - present Radiologic Society of North America - Scientific Program Committee for Breast Imaging 2014 - present Society of Breast Imaging - SAM/CME Committee 2014 - present International Society for Magnetic Resonance in Medicine – Young Investigator Award Subcommittee 2014 - present ECOG-ACRIN Breast Committee –Abbreviated Breast MRI Working Committee 2015 - present Society of Breast Imaging - Corporate Relations Committee 2015 - present American College of Radiology Committee on Practice Parameters – Breast Imaging 2015 International Society for Magnetic Resonance in Medicine - Annual Meeting Program Committee- Table Chair for Cancer Imaging 2015 - present American College of Radiology - Breast Screening Leadership Group 2015 - present American College of Radiology Joint Committee on Breast Imaging for the Appropriateness Criteria and Guidelines and Standards – Vice Chair 2015 - present American College of Radiology - Breast Commission, Communications Committee

2016 Radiologic Society of North America, Scientific Program Committee, Subcommittee Chair, Breast Imaging

Editorial Positions Editorship 2009 - 2010 MRI Clinics of North America – Breast MRI, Magn Reson Imaging Clin N Am. May;18(2):207-24, viii, 2010 2012 - present Deputy Editor for Breast Imaging - Journal of Magnetic Resonance in Imaging 2014 - present Consultant Editor - American Journal of Roentgenology SA-CME 2015 MRI Clinics of North America – Breast MRI, 2016 Breast Oncology: Techniques, Indications, and Interpretations. Springer

Ad hoc Reviewer 2008 - present Investigative Radiology 2008 - 2012 Journal of Magnetic Resonance in Imaging 2011 - present Journal of the National Cancer Institute 2013 - present Academic Radiology 2013 - present Magnetic Resonance in Medicine 2014 - present Clinical Imaging 2014 - present Journal of Clinical Oncology 2015 - present European Journal of Nuclear Medicine 2015 - present Radiology

Abstract Reviewer 2006 - 2011 American Society of Breast Disease 2011 - present International Society of Magnetic Resonance in Medicine 2012 - present American Roentgen Ray Society

Principal Clinical and Hospital Service Responsibilities 2000 - 2001 Attending Radiologist, Massachusetts General Hospital 2002 - present Attending Radiologist, New York University Langone Medical Center 2010 - 2015 Director, Fellowship in Breast Imaging - New York University School of Medicine

Major Administrative Responsibilities 1. NYU Breast Cancer Risk Assessment Program I am part of a Breast Cancer Risk Assessment Team at the NYU Clinical Cancer Center. We developed an algorithm for triaging women at high-risk for breast cancer. These women may have a strong family history or have been recently diagnosed with breast cancer. Our goal is to offer these women a tailored radiologic surveillance and clinical follow-up program and to foster interdisciplinary research efforts. We are in the process of offering a program at Bellevue Hospital and fostering our community outreach programs.

2. Breast MRI Program In 2007, I developed the Breast MRI program at the NYU Clinical Cancer Center. I helped to optimize breast MRI at 3.0 Tesla. In addition, I developed the Breast MRI Interventional Procedures Program. This breast imaging procedures include MR guided core biopsies and MRI localizations. Currently, the breast imaging section interprets approximately 1,200 breast MRI examinations and performs approximately 250 MRI guided procedures each year. In addition, I maintain the ACR accreditation for the Breast MRI and

MR interventional Program. Finally, I help to optimize our multi-parametric techniques for breast MRI at 3.0 T and 7.0T.

3. Fellowship Director for Breast Imaging I oversee 3 one-year non-ACGME accredited fellows. I supervise their fellowship at the NYU Cancer Institute, Bellevue Hospital and Gouveneur Health Services. In addition I developed the curriculum for the breast imaging fellowship. This curriculum is more advanced than the curriculum I developed for residents who are rotating through the breast imaging department. In addition, I oversee the fellows from other sections in the radiology department, surgery department and oncology department who are rotating through our service.

Teaching Experience Year Name of Course Type of Teaching Contact hours Harvard Medical School / Massachusetts General Hospital 1999 - 2001 Medical Student Lecture Series Lecturer 2 / week 1999 - 2001 Introduction to Diagnostic Radiology Lecturer 2 / week 1999 - 2000 Lymphoma Clinical-Pathologic Conference Lecturer 2 / month 1999 - 2001 Biopsy/Pathological Correlation Conference Lecturer 4 / week 1999 - 2001 Radiology Resident Teaching Conferences Lecturer 2 / week 1999 - 2001 Tumor Board Conference Lecturer 4 / week Lenox Hill Hospital 2002 - present Radiology Resident Case Conferences Lecturer 6 / year 2002 - present Radiology Resident Didactic Case Conference Lecturer 4 / year 2002 - present Radiology Resident Annual Board Review Lecturer 6 / year 2002 - present Interdisciplinary Breast Conference Attending physician 3 / year NYU Cancer Institute 2002 - present NYU Interdisciplinary Breast Conference Attending physician 6 / year Bellevue Hospital Radiology Resident Case Conferences Lecturer 6 / year 2002 - present Radiology Resident Didactic Case Conference Lecturer 4 / year 2002 - present Radiology Resident Annual Board Review Lecturer 6 / year 2002 - present Interdisciplinary Breast Conference Attending physician 3 / year NYU Cancer Institute 2002 - present NYU Interdisciplinary Breast Conference Attending physician 6 / year Bellevue Hospital Mt Sinai Medical Center 2005 - present Radiology Resident Conference Lecturer 3 / year NewYork-Presbyterian 2010 - present Radiology Resident Conference Lecturer 3 / year 2010 - present Radiology Best In Practice Lecture Series Lecturing 3 / year 2010 - present Fellow case conference Attending physician 3/ week 2010 - present Fellow journal club Attending physician 2 / month 2013 - present Advanced MRI Course Lecturer 3 / year

Mentoring of Graduate Students, Medical Students, Residents, Post-Doctoral Fellows in Research

Under my direct supervision: Name type of position time period present position

Present 1. Yiming Gao, MD Asst Professor 2015 - Asst Prof Radiology I mentored Dr. Gao since she arrived at NYU and became an assistant professor in breast imaging. To develop her mentorship skills, she functions in an advisory role as the mentor for Opeyemi Ibidapo. Dr. Gao is a co-author in 6 abstracts; 1 as the first author and 3 as the second author. She is a co-author in 2 original manuscripts and 2 review articles that are under review.

2. Samantha Heller, MD, PhD Volunteer researcher 2010 - Asst Prof Radiology I mentored Dr. Heller when she was a resident in diagnostic radiology and as a fellow in women’s imaging at NYU. I advised her to pursue an academic career. She was an attending radiologist, in the Department of Radiology, St. George’s Healthcare NHS Trust, London, United Kingdom and a volunteer researcher at NYU. We continued our research collaboration while she was abroad. In 2015, she returned to NYU as a faculty member. Under my mentorship, she is a co-author in 38 abstracts, 12 as the first author. Also, she is a co-author in 11 original manuscripts, reviews or book chapter, 8 as the first co-author.

3. Amy Melsaether, MD Resident, Asst Professor 2007 - Asst Prof Radiology I have mentored Dr. Melsaether when she was a resident in diagnostic radiology and as an assistant professor in breast imaging at NYU. I guided her decisions to pursue a breast imaging fellowship and to return to NYU as an attending physician. Under my mentorship, she updated the curriculum for radiology residents who rotate through the breast imaging section. Also we worked to develop a case conference and journal club for the residents. She is the primary faculty mentor for 3 residents and mentors other residents in advisory function. Under my supervision, she has led my section’s research in PET/MRI of the breast and is a member of several departmental committees, including the educational committee since 2010. I am also guiding her submission for a departmental seed grant. She is a co-author in 37 abstracts, 7 as the first author. She is a co-author in 10 original manuscripts and reviews.

4. Chloe Chhor, MD Asst Professor 2011 - Asst Prof Radiology I have mentored Dr. Chhor since she arrived at NYU and became an assistant professor in breast imaging. She assisted me with the mentoring of a fellow in breast imaging. To further develop her mentorship skills, she functioned in an advisory role as the mentor for Adrienne Newburg. Dr. Newburg pursued a six-month dedicated research elective during her last year of residency. Dr. Chhor has recently assumed the role of resident education for breast imaging. She is a co-author in 6 abstracts; 1 as the first author and 3 as the second author. She is a co-author in 2 original manuscripts that are in progress. She is developing a niche in the utility of ultrasound to detect palpable abnormalities and to evaluate enhancing lesions detected at breast MRI.

5. Jason McKellop, MD Resident, Fellow (Research) 2010 – Asst Prof Radiology I have mentored Dr. McKellop since he was a first-year resident in diagnostic radiology at NYU. I guided his decision to pursue breast imaging as a career. In addition, I was his mentor during his focused six- month research concentration. He is a co-author in 2 abstracts and a co-author in 3 manuscripts.

6. Alana Amarosa, MD Research Scientist, 2011-12, Radiology (Research), 2013- I have mentored Dr. Amarosa since she was a research scientist after graduating from the NYU School of Medicine. Presently, she is a fourth-year resident in diagnostic radiology at NYU. She is a co-author in 13 abstracts. She is a co-author in 4 manuscripts, the first author in three manuscripts. She was recently selected to be the young physician representative for the ACR Appropriateness Criteria.

7. Claudia Seuss, MD Radiology, Fellow (Research) 2012 - I have mentored Dr. Seuss since she was a second-year resident in diagnostic radiology at NYU. I guided her decisions to pursue breast imaging as a career. She is the first author in 4 abstracts that were oral presentations at RSNA. She is currently writing up a manuscript and completed a review article.

8. Laura Heacock, MD Resident (Research) 2013 – I have mentored Dr. Heacock since she was a first year radiology resident. Her research has focused on the abbreviated breast MRI exam. She is the only 4th year resident who selected to focus her fourth year on research. She is a co-author in 5 abstracts, 4 as the first author. She is the first author in two manuscripts.

9. Leng L.Y. Lin, MD Medical Student, resident 2013 - I mentored Dr. Lin since she was 4th year medical student at NYU. She pursued a two-month research elective under my direct supervision. Her research project is “Utility of a Second-Look Ultrasound to Detect Non-mass Enhancement Detected at Breast MRI”. She presented an abstract to ARRS 2014 and is a co-author on several abstracts that were presented at RSNA 2013 and RSNA 2014.

10. Neeti Bagadiya, MD Resident (Research) 2015 I have mentored Dr. Bagadiya since she was a first year radiology resident. She is a co-author in one manuscript and 2 abstracts.

11. Meghan Jardon Medical Student 2015 I supervised an eight week research selective.

12. Sonam Jaglan Medical Student 2015 I supervised an eight week research selective.

Past Sara Shaylor, MD Asst Professor 2011 – 15 Radiology attending Jin Ah Kim, MD Visiting Fellow 2013 – 14 Radiology attending Adrienne Newburg, MD Resident, Fellow (Research) 2013 – 2015 Radiology attending Nathan Margolies, MD Resident, Fellow (Research) 2013 – 2015 Radiology attending Jennifer Gillman, MD Medical Student, MSCI 2013 – 2015 Intern Natalie Plana Medical Student 2013 – 2014 Medical Student Carolyn Wassong, MD Resident, Fellow (Research) 2010 – 14 Radiology attending Avani Gupta, MD Resident, Fellow (Research) 2010 – 14 Radiology attending Katia Dodelzon, MD Resident, Fellow (Research) 2011 – 14 Radiology attending Ana P.K. Leite, MD Visiting Fellow 2012 - 13 Radiology attending Sarah Mijanos, MD Fellow (Breast Imaging) 2012 - 13 Radiology attending Sarah Palestrant, MD Fellow (Breast Imaging) 2012 - 13 Radiology attending Genevieve Abbey, MD Resident, Fellow 2012 - 13 Radiology attending Heather Greenwood, MD Resident (Research) 2009 - 13 Radiology attending Scott Degregorio, MD Resident (Research) 2010 -12 Radiology attending Dipti Gupta, MD Fellow (Breast Imaging) 2011 - 12 Radiology attending Samson Wong, MD Fellow (Women’s Imaging) 2011 - 12 Radiology attending Matt Lewis, MD Fellow (Women’s Imaging) 2010 - 11 Radiology attending Alice Kim, MD Fellow (Women’s Imaging) 2010 - 11 Radiology attending Caroline Aberg, MD Fellow (Breast Imaging) 2009 - 10 Radiology attending Yasmin Choudry-Clark, MD Fellow (Women’s Imaging) 2009 - 10 Radiology attending Suzanne McElligott, MD Fellow (Women’s Imaging) 2009 - 10 Radiology attending Myra Finn, MD Resident (Research) 2008 - 10 Radiology attending Victoria Mango, MD Resident (Research) 2007 - 11 Radiology attending Cristina Vieira, MD Resident (Research) 2007 - 10 Radiology attending Richard Do, MD, PhD Resident (Research) 2005 - 10 Radiology attending

Alison Levy, MD Resident (Research) 2005 - 7 Radiology attending

In advisory function: Present Name type of position time period Supervisor Gene Y Cho, BS Doctoral student, MRI physicist 2007 Eric Sigmund, PhD Kristin Elias, MD Resident, Fellow, Asst Prof 2008 Hildegard Toth, MD Eric Sigmund, PhD MRI physicist 2009 Christopher Collins, PhD Sungheon Kim, PhD MRI physicist 2010 Oded Gonen, PhD Ryan Brown, PhD Asst Professor 2010 Dan Sodickson, PhD Kristine Psyarenko, MD Fellow, Asst Professor 2010 Danny Kim, MD Guillaume Madelin, PhD MRI physicist 2013 Fernando Boada, PhD Marissa Albert, MD Resident (Research) 2013 Cathleen Heffernan,MD Akshat Pujara , MD Resident (Research) 2013 Amy Melsaether, MD Anjali Gudi, MD Resident (Research) 2013 Amy Melsaether, MD Islamiat Olaribigbe, MD Resident (Research) 2013 Cathy Petchaprapa, MD Anjali Gudi, MD Resident (Research) 2013 Amy Melsaether, MD Prodromos Parasoglu, PhD MRI physicist 2014 Christopher Collins, PhD Nivi Pinnamaneni, MD Resident (Research) 2014 Amy Melsaether, MD Elizabeth Geffen, MD Resident (Research) 2015 Yiming Gao, MD Luke Luke Mueller, MD, MBA Fellow (Breast Imaging) 2015 Amy Melsaether, MD Opeyemi Ibidapo, MD Resident, Fellow (Research) 2013 Yiming Gao, MD

Past Name type of position time period Supervisor Elizabeth Hecht, MD Fellow, Asst Prof 2004-2008 Vivian Lee, MD, PhD Ruth Lim, MD Asst Prof 2006-2009 Vivian Lee, MD, PhD Cristina Checka, MD Fellow (surgery) 2009-2012 Amber Guth, MD Ana Paula Refinetti, MD Fellow (surgery) 2011-2012 Freya Schnabel, MD Erica Friedman, MD Fellow (surgery) 2012 Freya Schnabel, MD Maxwell Janosky, MD Fellow (Surgery) 2013 Sylvia Adams, MD Jose Teurel, PhD MRI physicist 2015 Eric Sigmund, PhD Jason Ostenson MRI physicist 2015 Eric Sigmund, PhD Melanie Freed, PhD Postdoctoral fellow 2012 - 16 Sungheon Kim, PhD

Teaching Awards Received None

Major Research Interests 1. To optimize and assess the role of MR methods, such as diffusion-weighted imaging, intravoxel incoherent motion (IVIM) and quantification of contrast enhancement in the detection of mammographically occult breast cancer and to discriminate between benign and malignant lesions. 2. Outcomes analysis of breast MRI 3. Investigation of imaging features, such as background parenchymal enhancement and mammographic density, to determine if they are imaging biomarkers for an increase risk of breast cancer.

4. Assess the role of PET/CT and PET/MR imaging in the evaluation of breast cancer.

Grants Received Prior Agency Ttile Type & # Period Total Role % effort Direct Costs NIH MRIS studies of P30 6/09-2/13 $35,000 Pilot project 2.5% therapeutic response in CA016087 CI mouse breast cancer

models PI: Sungheon Kim, PhD DEPT A Non-invasive MRI Seed grant 3/11-3/14 $10,000 CI 10% Probe of Interstitial Fluid Pressure in Locally Advanced Breast Cancer PI: Eric Sigmund, PhD NIH Differentiation of 1UL 1/11-12/11 $12,000 Pilot project 2.5% malignant and benign RR02989 CI breast lesions using DCE- MRI PI: Sungheon Kim, PhD PTC A Phase Ib Study to Industry 5/08 – 6/11 Study Pilot project 5% Therapeutics Assess the Safety Profile, funded study paid for CI Pharmacokinetics, and drug

Anti-VEGF Activity of and PTC299 in Patients with imaging Metastatic Breast Cancer studies PI: Amy Tiersten, MD Dept Can the Specificity of Seed grant 11/02 – $10,000 Seed grant 10% MRI Breast Imaging Be 11/06 PI Improved by Fusing 3D MRI Volume Data Sets with FDG PET? Siemens Computer Aided Siemens 1/05 – 5/07 $13,000 Pilot Project 10% Detection Techniques to PI Reduce Motion Artifacts in Breast MRI Siemens Risk Assessment Model Siemens 5/05 – 6/08 $10,000 Pilot Project 10% in the Evaluation of PI Breast MRI

Current Agency Title Type & # Period Total Direct Role % Costs Effort ECOG- A Multicenter Study Evaluating 6702 3/14-2/17 $72,000 PI for NYU 5% the Utility of Diffusion Weighted ACRIN Imaging for Detection and Diagnosis of Breast Cancer

NIH DCE-MRI Study for Breast R01 3/12-1/17 $1,648,455 CI 5% Cancer CA160620 PI: Sungheon Kim, PhD ECOG- Prospective Study of Magnetic E4112 6/15-6/20 $15,000 PI for NYU 5% Resonance Imaging and ACRIN Multiparameter Gene Expression Assay in Ductal Carcinoma In Situ DOD Safety and Efficacy of SOM230 Idea 5/10 – $1,899,269 CI 2.5% for Chemoprevention of DCIS Award 11/15 PI: David Kleinberg, MD BC097854 ECOG- Effect of Preoperative Breast MRI 6694 7/14-7/18 $15,000 PI for NYU 5% on Surgical Outcomes, Costs and ACRIN Quality of Life of Women with Breast Cancer

Recent Submitted Grants Agency Title Type & # Period Total Direct Role % Costs Effort NIH Quantitative Sodium MRI for R21 11/16- $466,125 CI 5% Assessing Breast Cancer 11/19

PI: Guillaume Madelin, PhD NIH Assessment of the effects of oral R01 7/16-7/19 $2,163,033 Co-PI 15% contraceptives on the breast by

MRI PI: Anne Zeleniuch- Jacquotte, MD NIH Diffusion MRI study of treatment- R01 $2,377,861 CI 10% induced tumor vascular and

cellular changes DOD MRI study of saturated fat in the BCRP $600,000 Co-PI 15% breast and breast cancer Level1 DOD LARC implant: Impact on MRI BCRP $600,000 CI 5% breast cancer risk factors Level1

Patents None

Invited Seminars and Lectures

1. “State of the Art in Breast Imaging” Breast Cancer Diagnosis and Screening: An Interdisciplinary Approach - New Hampshire Office of Community and Public Health. Manchester, New Hampshire, November 2000

2. “Approaches to the Detection of Breast Cancer” Presented to Grand Rounds, Department of Medicine, Faulkner Hospital, Boston, MA, January 2001 3. “Current Diagnostic Dilemmas in Breast Imaging” Presented at New York University Breast Cancer Symposium, A Multidisciplinary Approach, NYU Medical Center, New York, NY March 2003 4. “State of the Art in Breast Imaging” Presented at Bicoastal Meeting Lynne Cohen Prevention Clinics, NYU Medical Center and USC/Norris Comprehensive Cancer Center, New York, NY, April 2004 5. “Breast MRI, New Imaging Analysis” Presented at Bicoastal Meeting Lynne Cohen Prevention Clinics, NYU Medical Center and USC/Norris Comprehensive Cancer Center, April 2005 6. “MR Mammography at 3.0 Tesla” Presented at the Nordic Mammography Screening Symposium VI, Copenhagen, Denmark, April 2006 7. “BIRADS Lexicon for Breast MR” Presented at 2006 Clinical 3.0 Tesla MRI Symposium, Las Vegas, Nevada, May 2006 8. “Breast MRI and MR Spectroscopy on the 3.0 Tesla” Presented at the 24th Annual Magnetic Resonance Imaging 2007, Las Vegas, Nevada, April 2007 9. “Evaluation of Breast Cancer with Breast MRI” Presented at the 24th Annual Magnetic Resonance Imaging 2007, Las Vegas, Nevada, April 2007 10. “Breast Cancer Screening, an Update” Presented at Bicoastal Meeting Lynne Cohen Prevention Clinics, NYU Medical Center and USC/Norris Comprehensive Cancer Center, April 2007 11. “Clinical Applications of Breast MRI” Presented at the American Roentgen Ray Society, Annual Meeting, Orlando, Florida, May 2007 12. “3.0 Tesla Breast MRI and MR Spectroscopy” Presented at the New York Roentgen Society Annual Spring Meeting, New York, NY, May 2007 13. “When is Breast MRI Indicated?” Presented at the American Roentgen Ray Society: Practical Breast MRI Course, Las Vegas, Nevada, January 2008 14. “How I do it: Protocols and Tips” Presented at the American Roentgen Ray Society: Practical Breast MRI Course, Las Vegas, Nevada, January 2008 15. “Common Problems in the Evaluation of Breast MRI” Presented at the American Roentgen Ray Society: Practical Breast MRI Course, Las Vegas, Nevada, January 2008 16. “Advanced MR Techniques” Presented at the American Roentgen Ray Society: Practical Breast MRI Course, Las Vegas, Nevada, January 2008 17. “MR-guided Interventions” Presented at the American Roentgen Ray Society: Practical Breast MRI Course, Las Vegas, Nevada, January 2008 18. “Use of Breast MRI BI-RADS” Presented at the New England Roentgen Ray Society’s Annual Refresher Course, March 2008 19. “Breast MRI and Computer Aided Detection” Presented at the International Society of Magnetic Resonance in Medicine, 16th Scientific Meeting and Exhibition, Toronto, Canada, May 2008 20. “Emerging Trends in Breast MRI – 3.0 Telsa imaging including MR Spectroscopy” Presented at the World Class Breast Imaging, Washington DC, August 2008 21. “Clinical Indications for Breast MRI” Presented at the World Class Breast Imaging, Washington DC, August 2008 22. “Clinical Indications for Breast MRI” Presented at the New York Roentgen Society Annual Spring Meeting, New York, NY, May 2009 23. “Management of BIRADS 3 Probably Benign Lesions Detected on Breast MRI” Presented at the New York Roentgen Society Annual Spring Meeting, New York, NY, May 2009 24. “How to Optimize Breast MRI Techniques at 1.5T and 3.0T” Presented at SMRT, NYU Medical Center, New York, November 2009 25. “Plenary Session: Breast Cancer Screening” Presented at Bridging the Gap: Medicine, the Media and Women’s Health, NYU Skirball Center, New York, April 2010 26. “Breast Series: Breast MR Imaging” Moderator at the Radiologic Society of North America, Chicago IL, Nov 2011

27. “The Probably Benign Breast MRI” Presented at the New York Breast Imaging Society” New York, NY, February 2012 28. “Breast Cancer Scientific Session” Moderator at the International Society of Magnetic Resonance in Medicine, Melbourne, Australia, May 2012 29. "Probably Benign" Findings on Breast MR: Criteria, Follow-Up and Results” Presented at Mt. Sinai Update 2012: Breast Imaging" New York, NY, October 2012 30. “Breast Series: Breast MR Imaging” Moderator at Radiologic Society of North America, Chicago IL, Nov 2012 31. “Breast Cancer Scientific Session” Moderator at the International Society of Magnetic Resonance in Medicine, Salt Lake City, Utah, April 2013 32. “Breast MRI: Optimal Technique, Artifacts and Pitfalls” American Roentgen Ray Society Annual Meeting, Washington, DC, April 2013 33. “Update on MRI Screening for Breast Cancer” American Roentgen Ray Society Annual Meeting, Washington, DC, April 2013 34. "Probably Benign" Findings on Breast MR: Criteria, Follow-Up and Results” Presented at the New York Breast Imaging Society, New York, NY, May 2013 35. “Update on the New BI-RADS MRI Lexicon” Presented at the New York Roentgen Society Annual Meeting, New York, NY, October 2013 36. “Breast Series: Breast MR Imaging” Moderator at Radiologic Society of North America, Chicago IL, Nov 2013 37. “Simultaneous acquisition of Breast Imaging with PET/MRI a powerful tool to better classify lesions”, 26th Annual European Congress of Radiology, Vienna Austria, March 2014 38. “Breast Cancer Advanced Imaging Symposium” Moderator of Siemens & Bayer Breast Care Day 26th Annual European Congress of Radiology, Vienna Austria, March 2014 39. “Breast MRI” Grand Rounds Speaker. Westchester Medical Center, April 2014 40. “Non-Proton MRS Spectroscopy” Moderator at the International Society of Magnetic Resonance in Medicine, Milan, Italy, May 2014 41. “Challenging Cases in Breast MRI” Presented at the New York Roentgen Society Annual Meeting, New York, NY, October 2014 42. “Diagnostic Breast MR Imaging” Moderator at Radiologic Society of North America, Chicago IL, November 2014 43. “Multi-Modality Approaches to Breast MRI” Presented at the International Society of Magnetic Resonance in Medicine, Workshop on MRI in the Management of Breast Disease: Past, Present & Future, San Francisco, California, February 2015 44. “What Have We Learned from the Breast Clinical Trials?” Moderator at the International Society of Magnetic Resonance in Medicine, Workshop on MRI in the Management of Breast Disease: Past, Present & Future, San Francisco, California, February 2015 45. “Role of Breast MRI” Grand Rounds Speaker, SUNY Brooklyn, New York, NY March 2015 46. “The Path is Back: Now What? Volume 2 (MR)” SBI/ACR Breast Imaging Symposium, Orlando, FL, April 2015 47. "Update on the ACR BI-RADS MRI Lexicon" Presented at the New York Breast Imaging Society, New York, NY, May, 2015 48. “Breast Cancer Scientific Session” Moderator at the International Society of Magnetic Resonance in Medicine, Toronto, Canada, May 2015 49. “Abbreviated Breast MRI” Grand Rounds Speaker, Brigham’s and Women Hospital, Boston, MA, June 2015 50. ‘Multiparametric Approach to Breast MRI” Grand Rounds Speaker, Massachusetts General Hospital, Boston, MA June 2015 51. ‘PET/MRI Breast” Grand Rounds Speaker, Northwestern Hospital, IL October 2015 52. “Diagnostic Breast MR Imaging” Moderator at Radiologic Society of North America, Chicago IL, December 2015

53. “Breast Cancer Roundtable with Bloomberg News” Speaker, New York, NY December 2015 54. “Taking Cases with the Experts: BI-RADS Multi-Modality” Speaker at the Society of Breast Imaging/ American College of Radiology Breast Imaging Symposium, Austin, Tx, April 2016 56. “Role of Breast MRI in High Risk Women” Keynote speaker, American Roentgen Ray Society Annual Meeting, Los Angeles, CA, April 2016 57. “Clinical Cancer MRI: Case Based Review” Organizer and Moderator at the International Society of Magnetic Resonance in Medicine, Singapore, May 2016 58. “Multiparametric MRI of Cancer” Organizer and Moderator at the International Society of Magnetic Resonance in Medicine, Singapore, May 2016 59. “Plenary Session: Multiparametric MRI of Cancer” Organizer and Moderator at the International Society of Magnetic Resonance in Medicine, Singapore, May 2016 60. “At the Cutting-Edge of Cancer Imaging” Moderator at the International Society of Magnetic Resonance in Medicine, Singapore, May 2016 61. “Breast MRI in High and Intermediate Risk Women” To be presented at the New York Roentgen Society Annual Meeting, New York, NY, October 2016

Post-Graduate Medical Lectures 1. “Radiologic Detection of Breast Cancer” Lecturer at 2000 New England Cancer Society Massachusetts General Hospital and Harvard Medical School Continuing Medical Education, November 2000 2. “Introduction to Breast Imaging” Teleradiology Conference, Partners Telemedicine Partners Healthcare, Massachusetts General Hospital, and Harvard Medical School Continuing Medical Education, December 2000 3. “Breast MRI – Clinical Utility and Pitfalls” Presented at MRI: Clinical State of the Art, NYU Medical Center, New York, NY, October 2004 4. “How to Interpret Breast MRI in the Cancer Patient” Presented at MRI: Clinical State of the Art, NYU Medical Center, New York, NY, October 2005 5. “BIRADS MRI Lexicon: An Update” Presented at the Head to Toe Imaging Conference, NYU Medical Center, New York, NY, December 2005 6. “Breast MRI: The Pre-operative Assessment” Presented at the Head to Toe Imaging Conference, NYU Medical Center, New York, NY, December 2005 7. “Cases of the Day – Women’s Imaging” Presented at MRI: Clinical State of the Art, NYU Medical Center, New York, NY, October 2006 8. “Emerging Trends in Breast MRI” Presented at the Head to Toe Imaging Conference, NYU Medical Center, New York, NY, December 2006 9. “Breast MRI, a Practical Approach” Presented at MRI: Clinical State of the Art, NYU Medical Center, New York, NY, October 2007 10. “Emerging Trends in Breast MRI” Presented at Fall into Women’s Imaging: An NYU Autumn Update of Breast and Women’s Imaging Essentials, Manchester Village, Vermont, October 2007 11. “Role of Breast MRI in the Evaluation of Breast Cancer” Presented at fall into Women’s Imaging: An NYU Autumn Update of Breast and Women’s Imaging Essentials, Manchester Village, Vermont, October 2007 12. “Evaluation of Breast Cancer with Breast MRI” Presented at the Head to Toe Imaging Conference, NYU Medical Center, New York, NY, December 2007 13. “MR-guided Interventions” Presented at the NYU Summer Radiology Symposium on the Cape, NYU Medical Center, Chatham, MA, June 2008 14. “Role of MRI in the Evaluation of Breast Cancer” Presented at the NYU Summer Radiology Symposium on the Cape, NYU Medical Center, Chatham, MA, June 2008 15. “Digital Mammography: An Update” Presented at the NYU Summer Radiology Symposium on the Cape, NYU Medical Center, Chatham, MA, June 2008

16. “Breast Imaging: Challenging Case Review” Presented at the NYU Summer Radiology Symposium on the Cape, NYU Medical Center, Chatham, MA, June 2008 17. “Role of MRI in the Evaluation of Breast Cancer” Presented at the Head to Toe Imaging Conference, NYU Medical Center, New York, NY, December 2008 18. “MR-guided Interventions” Presented at the Essentials of Imaging in Costa Rica, NYU Medical Center, Costa Rica, January 2009 19. “Role of MRI in the Evaluation of Breast Cancer” Presented at the Essentials of Imaging in Costa Rica, NYU Medical Center, Costa Rica, January 2009 20. “Digital Mammography: An Update” Presented at the Essentials of Imaging in Costa Rica, NYU Medical Center, Costa Rica, January 2009 21. “Breast Imaging: Challenging Case Review” Presented at the Essentials of Imaging in Costa Rica, NYU Medical Center, Costa Rica, January 2009 22. “BI-RADS for Breast US” Presented at the Essentials of Imaging in Costa Rica, NYU Medical Center, Costa Rica, January 2009 23. “Clinical indications for Breast MRI” Presented at MRI: Clinical State of the Art, NYU Medical Center, New York, September 2009 24. “Clinical Indications for MRI” Presented at the Head to Toe Imaging Conference, NYU Medical Center, New York, NY, December 2009 25. “BI-RADS 3 Lesions; Probably Benign Findings detected on Breast MRI” Presented at the Head to Toe Imaging Conference, NYU Medical Center, New York, NY, December 2009 26. “Technical and Clinical Considerations for Digital Mammography” Presented at the Clinical Imaging Update in Jackson Hole, NYU Medical Center, Jackson Hole, August 2010 27. “BI-RADS for Breast Ultrasound, A Case-Base Approach” Presented at the Clinical Imaging Update in Jackson Hole, NYU Medical Center, Jackson Hole, August 2010 28. “Breast MRI, Clinical Applications” Presented at the Clinical Imaging Update in Jackson Hole, NYU Medical Center, Jackson Hole, August 2010 29. “Probably Benign Findings detected on Breast MRI” Presented at the Clinical Imaging Update in Jackson Hole, NYU Medical Center, Jackson Hole, August 2010 30. “Interesting Cases of the Day” Presented at the Clinical Imaging Update in Jackson Hole, NYU Medical Center, Jackson Hole, August 2010 31. “ACR Breast MRI Accreditation” Presented at MRI: Clinical State of the Art, NYU Medical Center, New York, October 2010 32. “Breast MRI: Does it Make a Difference?” Presented at MRI: Clinical State of the Art, NYU Medical Center, New York, October 2010 33. “How Breast MRI Has Changed Our Practice – What Have We Learned?” Presented at the Head to Toe Imaging Conference, NYU Medical Center, New York, NY, December 2010 34. “Multimodality Breast Imaging: Challenging Cases on Mammography, Ultrasound, and MRI” Presented at the Head to Toe Imaging Conference, NYU Medical Center, New York, NY, December 2010 35. “Management of Probably Benign Lesions Detected on Breast MRI” Presented at the Head to Toe Imaging Conference, NYU Medical Center, New York, NY, December 2011 36. “Update on Screening Mammography and Screening Breast US” Presented at the NYU Clinical Imaging Symposium in Maui, January 2012 37. “Clinical Utility of Breast MRI” Presented at the NYU Clinical Imaging Symposium in Maui, January 2012 38. “Strategies for Finding Commonly Missed Subtle Findings of Breast CA” Presented at the NYU Clinical Imaging Symposium in Maui, January 2012 39. “Management of Probably Benign Breast Lesions” Presented at the NYU Clinical Imaging Symposium in Maui, January 2012 40. “Challenging Breast Ultrasound Cases” Presented at the NYU Clinical Imaging Symposium in Maui, January 2012

41.“Breast MRI: Management of the Probably Benign Lesion” Presented at the Head to Toe Imaging Conference, NYU Medical Center, New York, NY, December 2013 42. “SAM Part 3: Update on Probably Benign Lesions Determined on Breast MRI” Presented at the Head to Toe Imaging Conference, NYU Medical Center, New York, NY, December 2013 43. “Systematic Approach to Breast MRI and Case Based Review of New MRI BIRADS Lexicon” Presented at the NYU Clinical Imaging Symposium in Nevis, January 2014 44. “Strategies for Finding Commonly Missed Subtle Findings of Breast Cancer” Presented at the NYU Clinical Imaging Symposium in Nevis, January 2014 45. “Digital Tomosynthesis: Is it Ready for Primetime? Presented at the NYU Clinical Imaging Symposium in Nevis, January 2014 46. “Role of Screening Breast Ultrasound and Screening MR” Presented at the NYU Clinical Imaging Symposium in Nevis, January 2014 47. “Interesting Cases: Breast Imaging” Presented at the NYU Clinical Imaging Symposium in Nevis, January 2014 48. “Clinical Indications for Breast MRI in 2014” Presented at the Head to Toe Imaging Conference, NYU Medical Center, New York, NY, December 2014 49. “Clinical Indications for Breast MRI in 2015” Presented at the Head to Toe Imaging Conference, NYU Medical Center, New York, NY, December 2015 50. “A Practical Approach to Detect Commonly Missed Findings of Breast Cancer on Mammography and Tomosynthesis” Presented at the NYU Clinical Imaging Symposium in Costa Rica, January 2016 51. “Challenging Breast Imaging Cases” Presented at the NYU Clinical Imaging Symposium in Costa Rica, January 2016 52. “Clinical Role of Breast MRI in 2016” Presented at the NYU Clinical Imaging Symposium in Costa Rica, January 2016 53. “Review of ACR Appropriateness Criteria for Breast Pain, Lump, Male Breast, and Everything Else” Presented at the NYU Clinical Imaging Symposium in Costa Rica, January 2016 54. “Update on Breast Cancer Screening with Mammography, Ultrasound and Tomosynthesis” Presented at the NYU Clinical Imaging Symposium in Costa Rica, January 2016

Workshops 1. “Ultrasound Procedures in Breast Imaging – Hands-On Workshop” Workshop Presenter at 2000 Breast Imaging: A Team Approach, Massachusetts General Hospital and Harvard Medical School Continuing Medical Education 2. “Case Base Approach to ACR-BIRADS MRI Lexicon” Workshop presentation at the Head to Toe Imaging Conference, NYU Medical Center, New York, NY, December 2006 3. “Breast MRI lesion analysis and interpretation: Case-based review” Presented at the Head to Toe Imaging Conference, NYU Medical Center, New York, NY, December 2013 4. “Using the New MRI BI-RADS: Case-based Review” Presented at the Head to Toe Imaging Conference, NYU Medical Center, New York, NY, December 2014

Boards and Community Organizations National Breast Cancer Foundation American Cancer Society Susan G. Komen for the Cure Women's Health Initiative

Military Service None

Other N/A

Bibliography

Original Reports: 1. Smith T, Moy L, Runowicz C. Mixed Mullerian Tumors: CT Characteristics with Clinical and Pathological Observations. American Journal of Roentgenology 1997 Aug;169(2):531-5. 2. Umans H, Liebling M, Moy L, Haramati N, Pritzker H. Slipped Capital Femoral Epiphysis - A Physeal Lesion Evaluated by MRI and CT. Skeletal Radiology 1998 Mar;27(3):139-44. 3. Moy L, Slanetz PJ, Yeh ED, Kopans DB. The Pendent View – An Additional Projection To Secure the Diagnosis of Milk of Calcium. American Journal of Roentgenology 2001 Jul;177(1):173-5. 4. Moy L, Kopans DB, Slanetz PJ, Poller J, Moore RH. The Specificity of Mammography and Ultrasound in the Evaluation of a Palpable Abnormality. Radiology 2002 Oct;225(1):176-81. 5. Yeh ED, Slanetz PJ, Kopans DB, Rafferty E, Georgian-Smith D, Moy L, Halpern E, Moore R, Kuter I, Taghian A. Prospective Comparison of Mammography, Breast Ultrasound and Magnetic Resonance Imaging in Patients Undergoing Neoadjuvant Chemotherapy for Palpable Breast Cancer. American Journal of Roentgenology 2005 Mar;184(3):868-77. 6. Moy L, Ponzo F, Noz M, Maguire G, Deans A, Murphy-Walcott A, Kramer E. A Prone MammoPET Acquisition Device Improves the Ability to Fuse MRI and PET Breast Scans. Clinical Nuclear Medicine 2007 Mar;32(3):194-8. 7. Moy L, Ponzo F, Noz M, Maguire G, Deans A, Murphy-Walcott A, Deans A, Kitazono MK, Travascio L, Kramer E. Improving Specificity of Breast MRI Using Prone PET Imaging and Fused MRI and PET 3D Volume Data Sets. J Nucl Med. 2007 Apr;48(4):528-37. 8. Mercado C, Guth A, Axelrod A, Moy L, Toth H, Cangiarella J. Sonographically Guided Clip Placement Facilitate Confirmation of Removal of Mammographically Occult Lesions After Localization. American Journal of Roentgenology 2008 Oct;191(4):1216-9. 9. Moy L, Elias K, Patel V, Lee J, Babb JS, Toth HK, Mercado CL. Is breast MRI helpful in the evaluation of inconclusive mammographic findings? American Journal of Roentgenology 2009 Oct;193(4):986-93. 10. Vieira CC, Mercado CL, Cangiarella JF, Moy L, Toth HK, Guth AA. Microinvasive ductal carcinoma in situ: clinical presentation, imaging features, pathologic findings, and outcome. European Journal of Radiology 2010 Jan;73(1):102-7. 11. Moy L, Noz ME, McGuire G, Melsaether A, Deans AE, Murphy A, Ponzo F. Improving MR Specificity - Role of Fusion of Prone FDG-PET/CT and Magnetic Resonance Imaging of the Breasts in the Evaluation of Breast Cancer. Breast Journal 2010 Jul-Aug;16(4):369-76. 12. Raykar VC, Yu S, Zhao LH, Valadez GH, Florin C, Bogoni L, Moy L. Learning from the Crowds. Journal of Machine Learning Research 2010 11(Apr):1297−1322. 13. Sigmund EE, Cho GY, Kim S, Finn M, Moccaldi M, Jensen J, Sodickson D, Goldberg J, Formenti S, Moy L. Intra-voxel incoherent motion (IVIM) imaging of tumor microenvironment in Locally Advanced Breast Cancer. Magnetic Resonance in Medicine 2011; 65:1437-1447. 14. Kim S, Decarlo L. Cho GY, Jensen H, Sodickson DK, Moy L, Formenti S, Schneider R, Goldberg JD, Sigmund EE. Interstitial fluid pressure correlates with intra-voxel incoherent motion imaging metrics in mouse mammary carcinoma model. NMR in biomedicine 2012 May;25(5):787-94. doi: 10.1002/nbm.1793. Epub 2011 Nov 9. PMID:22072561

15. Clendenen TV, Kim S, Moy L, Wan L, Rusinek H, Stanczcyk F, Pike MC, Zeleniuch-Jacquotte A. "Magnetic resonance imaging of hormone-induced breast changes in young premenopausal women”. , Magnetic Resonance Imaging 2013 Jan;31(1):1-9. doi: 10.1016/j.mri.2012.06.022. Epub 2012 Aug 13. PMID: 22898693 16. Heller SL, Moy L, Lavianlivi S, Moccaldi M, Kim S. Magnetization Transfer Imaging and Dynamic Contrast Enhanced Imaging of Breast Cancer at 3T. Journal of Magnetic Resonance Imaging 2013 Jan;37(1):138-45. doi: 10.1002/jmri.23786. Epub 2012 Oct 23. PMID: 23097239 17. Clendenen TV, Zeleniuch-Jacquotte A, Moy L, Pike MC, Rusinek H, Kim S. Comparison of 3-point Dixon imaging and fuzzy C-means clustering methods for breast density measurement. J Magn Reson Imaging. 2013 Aug;38(2):474-81. doi: 10.1002/jmri.24002. Epub 2013 Jan 4. PMID:23292922 18. Amarosa AR, McKellop J, Klautau Leite AP, Moccaldi M, Clendenen T, Zeleniuch-Jacquotte A, Moy L, Kim S. Evaluation of the kinetic properties of background parenchymal enhancement across phases of the menstrual cycle. Radiology 2013 Aug;268(2):356-65. doi: 10.1148/radiol.13121101. Epub 2013 May 8. PMID:23657893 19. Brown R, Storey P, Geppert C, McGorty K, Klautau Leite AP, Babb J, Sodickson DK, Wiggins GC, Moy L. Breast MRI at 7 Tesla with a bilateral coil and T1-weighted acquisition with robust fat suppression: image evaluation and comparison with 3 Tesla. European Journal of Radiology, 2013 Nov;23(11):2969-78. doi: 10.1007/s00330-013-2972-1. Epub 2013 Jul 30. PMID:23896763 20. Heller SL, Elias K, Gupta A, Greenwood HI, Mercado CL, Moy L. Outcome of High-Risk Lesions at MRI-guided 9-gauge Vacuum Assisted Breast Biopsy. American Journal of Roentgenology, 2014 Jan;202(1):237-45. doi: 10.2214/AJR.13.10600. PMID: 24370150 21. Brown R, Storey P, McGorty K, Geppert C, Klautau Leite AP, Babb J, Sodickson DK, Wiggins GC, Moy L. Breast MRI at 7 Tesla with a Bilateral Coil and Robust Fat Suppression. Journal of Magnetic Resonance Imaging 2014 Mar;39(3):540-9. doi: 10.1002/jmri.24205. Epub 2013 Oct 7. PMID:24123517 22. E Friedman; J Chun; F Schnabel; S Schwartz; S Law; J Billig; E Ivanoff ; L Moy; D Axelrod; AA Guth. Screening Prior to Breast Cancer Diagnosis: The More Things Change, the More They Stay the Same. International Journal of Breast Cancer. 2013;2013:327567. doi: 10.1155/2013/327567. Epub 2013 Sep 18.PMID:24159387 23. Shaylor SD, Heller SL, Melsaether AN, Gupta D, Gupta A, Babb J, Moy L. Short Interval Follow-Up After A Benign Concordant MR-Guided Vacuum Assisted Breast Biopsy – Is it Worthwhile? Eur Radiol. 2014 Jun;24(6):1176-85. doi: 10.1007/s00330-014-3125-x. Epub 2014 Mar 14. PMID: 24623366 24. Melsaether AN, McDermott M; Gupta D, Pysarenko K, Shaylor SD, Moy L. Inter-reader Variability in Assessment of Background Parenchymal Enhancement on Breast MRI Improves with Dedicated Training. American Journal of Roentgenology. 2014 Jul;203(1):209-15. doi: 10.2214/AJR.13.10952. PMID: 24951217 25. Janosky M, Bian J, Dhage S, Levine J, Silverman J, Jors K, Moy L, Cangiarella J, Muggia F, Adams S. Primary Large Cell Neuroendocrine Carcinoma of the Breast, a case report with an unusual clinical course. Breast Journal 2015 May;21(3):303-7. doi: 10.1111/tbj.12403. Epub 2015 Mar 30. PMID: 25823996 26. Cho GY, Moy L, Zhang JL, Lattanzi R, Baete S, Moccaldi, , Babb J, Kim S, Sodickson DK, Sigmund EE. Optimized b value selection for intravoxel incoherent motion (IVIM) analysis of diffusion-weighted imaging in breast cancer. Magn Reson Med. 2014 Oct 9. doi: 10.1002/mrm.25484. PMID:25302780 27. Margolies N, Bassiri-Tehrani B, Chhor C, Singer C, Hernandez O, Moy L. Polyacrylamide Gel Breast Augmentation: A Case-Based Review of the Literature. Clinical Imaging 2015 May-Jun;39(3):339-343. doi: 10.1016/j.clinimag.2014.12.008. Epub 2014 Dec 20. PMID: 25670236 28. Kim S, Feng L, Grimm R, Freed M, Block KT, Sodickson DK, Moy L, Otazo R. Assessment of iterative Golden-angle RAdial Sparse Parallel (iGRASP) MRI for breast dynamic contrast enhanced MRI. J Magn Reson Imaging. 2015 Jun 1. doi: 10.1002/jmri.24961. PMID: 26032976

29. Janosky M, Sabado R, Cruz C, Vengco I, Hasan F, Winer A, Moy L, Adams S. Ex-vivo detectable MAGE-specific T cells correlate with complete remission in metastatic breast cancer patients after sequential immune-endocrine therapy. Journal for ImmunoTherapy of Cancer 2014 :32 http://www.immunotherapyofcancer.org/content/2/1/32. Doi: 10.1186/s40425-014-0032-2 30. Cho GY, Moy L, Kim S, Leite APK, Baete S, Babb JS, Sodickson DK, Sigmund EE. Comparison of Contrast Enhancement and Diffusion-Weighted Magnetic Resonance Imaging in Healthy and Cancerous Breast Tissue, European Journal of Radiology. 2015 Jul 2. pii: S0720-048X(15)30030-9. doi: 10.1016/j.ejrad.2015.06.023. PMID: 26220915 31. Albert M, Schnabel F, Chun J, Schwartz S, Lee J, Klautau Leite AP, Moy L. “The Relationship of Breast Density in Mammography and Magnetic Resonance (MR) Imaging in Women at High Risk for Developing Breast Cancer and Women with Breast Cancer.” Clin Imaging. 2015 Aug 6. pii: S0899- 7071(15)00218-1. doi: 10.1016/j.clinimag.2015.08.001. PMID: 26351036) 32. Moy L. Letter to the Editor in Response to a Recent Commentary, "Mammography Trials" by Drs. Saurabh Jha and Jeffrey B. Ware. Acad Radiol. 2015 Oct 27. pii: S1076-6332(15)00408-0. doi: 10.1016/j.acra.2015.08.029. PMID: 26514434 33. Cho GY, Moy L, Kim SG, Babb J, Baete S, Sodickson DK, Sigmund EE. Evaluation of Breast Cancer using Intravoxel Incoherent Motion (IVIM) histogram analysis: Comparison with malignant status, histological subtype, and molecular prognostic factors. European Radiology 2015 Nov 28. [Epub ahead of print] PMID: 26615557 34. Pujara AC, Raad RA, Ponzo F, Wassong C, Babb JS, Moy L, Melsaether AN. Standardized Uptake Values from PET/MRI in Metastatic Breast Cancer: An Organ-based Comparison with PET/CT. Breast J. 2016 Feb 4. doi: 10.1111/tbj.12569. [Epub ahead of print] PMID: 26843433 35. Amarosa AR, Kim S,G Melsaether AN, McKellop J, Moccaldi M, Klautau Leite AP, Moy L. Differentiation of Benign from Malignant Non-Mass Enhancement in BRCA 1 Mutation Carriers Using Quantitative Kinetic Analysis. Acad Radiol. 2016 Mar;23(3):358-67. doi: 10.1016/j.acra.2015.11.011. Epub 2016 Jan 7. 36. Moy L. Letter to the Editor in Response to a Recent Commentary, “New Guidelines for Breast Cancer Screening in US Women” by Drs. Keating NL, Pace LE. JAMA. 2016 Apr 5;315(13):1404-5. doi: 10.1001/jama.2015.19072. No abstract available. PMID: 27046373 37. Heacock L, Melsaether AN, Heller SL, Gao Y, Pysarenko KM, Babb JS, Kim SG, Moy L. Evaluation of a Known Breast Cancer Using an Abbreviated Breast MRI Protocol: Correlation of Imaging Characteristics and Pathology with Lesion Detection. European Journal of Radiology 2016 85(4):815-823 (# 2031312) 38. Melsaether AN, Rakheja R, Pysarenko K, Ponzo F, Jhaveri K, Sigmund EE, Kim S, Moy L. Comparison of whole body 18FDG-PET/MRI and whole body 18FDG-PET/CT in terms of lesion detection and radiation dose in breast cancer patients. Radiology. 2016 Mar 29:151155. [Epub ahead of print] PMID: 27023002 39. Margolis NE, Moy L, Pujara A, Amarosa A, Sigmund EE, Geppert C, Glielmi C, Freed M, Feng L, Otazo R, Melsather AN, Kim SG. Pharmacokinetic modeling in simultaneous dynamic contrast enhanced breast MRI and PET imaging. Clin Nucl Med. 2016 May 13. [Epub ahead of print] PMID: 27187730 40. Freed M, Storey P, Lewin AA, Babb J, Moccaldi M, Moy L, Kim SG. Evaluation of lipid composition in patients with benign tissue and cancer using multiple gradient echo MRI. Radiology (in press)

41. Gao Y, Bagadiya N, Jardon M, Heller SL, Melsaether AN, Toth HB, Moy L. Outcomes of Preoperative MR-imaging guided Needle Localization of Nonpalpable, Mammographically Occult Breast lesions. AJR (in press) 42. Gillman J, Batel J, Schnabel F, Chun C, Schwartz S, Moy L. Characteristics in a Contemporary Cohort of Younger Women with Newly Diagnosed Breast Cancer. Clinical Breast Cancer (in press) 43. Heller SL, Jaglan S, Babb JS, Melsaether A, Toth HB, Moy L. Frequency of Discordant Lesions and False Negative Cancers at Stereotactic Vacuum Assisted Biopsy. Acad Radiol. 2016 May 5. pii: S1076- 6332(16)30026-5. doi: 10.1016/j.acra.2016.03.023. [Epub ahead of print]PMID: 27161209 44. Teruel JR, Cho GY, Moccaldi M, Goa PE, Bathen TF, Kim SG, Moy L, Sigmund EE. Stimulated Echo Diffusion Tensor Imaging (STEAM-DTI) with Varying Diffusion Times as a Probe of Breast Tissue: preliminary experience. JMRI (in press) 45. Newburg A, Chhor C, Lin LLY, Heller SL, Gillman J, Toth H, Moy L. MRI-directed Ultrasound of Non-mass Enhancement: Outcomes and Frequency of Malignancy. Journal of Ultrasound in Medicine (in press) 46. Lewin L, Heller S, Jaglan S, Elias K, Newburg A, Moy L. Radiologic-Pathologic Discordance and Outcome After MRI-Guided Vacuum Assisted Biopsy. AJR (in press) 47. Melsaether, A Pujara A, Elias K, Pysarenko K, Gudi, A, Dodedelzon K, Babb J, Gao Y, Moy L. Background parenchymal enhancement over exam time in patients with and without breast cancer. JMRI (in press)

Reviews, Books, and Book Chapters

1. Moy L, Mercado CL. Interpretation and clinical applications of Breast MRI: Self-assessment module. American Journal of Roentgenology 2008 Dec;191(6 Suppl):S60-7. 2. Mercado CL, Moy L. Breast MRI. Preface. Magn Reson Imaging Clin N Am. 2010 May;18(2):xiii 3. Chatterji M, Mercado CL, Moy L. Optimizing 1.5 Tesla and 3.0 Tesla Dynamic Contrast-Enhanced Magnetic Resonance Imaging of the Breasts. Magn Reson Imaging Clin N Am. 2010 May;18(2):207-24, viii. 4. Heller S, Moy L. "Imaging Features and Management of High Risk Lesions on Contrast-Enhanced Dynamic Breast MRI." American Journal of Roentgenology 2012 Feb;198(2):249-55. 5. Heller SL, Moy L. Breast MRI: Optimal Technique, Artifacts, and Pitfalls. American Roentgen Ray Society 2013 CAT 12-9915 6. Heller SL, Hernandez O, Moy L. Radiologic-Pathologic Correlation at Breast MRI—What is the Appropriate Management for High-Risk Lesions? Magn Reson Imaging Clin N Am. 2013 Aug;21(3):583- 99. doi: 10.1016/j.mric.2013.03.001. Epub 2013 May 16. PMID:23928247 7. Greenwood HI, Heller SL, Kim S, Sigmund E, Shaylor SD, Moy L. “Ductal Carcinoma in Situ: A Review of the Imaging Features on MR Imaging of the Breasts” Greenwood HI, Heller SL, Kim S, Sigmund EE, Shaylor SD, Moy L. Radiographics. 2013 Oct;33(6):1569-1588. PMID:24108552 8. Heller S, Moy L. Screening for Breast Cancer with Magnetic Resonance Imaging. Breast MRI: Expert Consult: Online and Print, Chapter 4. Pages 32 – 40. ISBN 13: 9781455740611 ISBN 10: 1455740616 9. Palestrant S, Comstock CE, Moy L. Approach to Breast MRI Interpretation. Radiol Clin North Am. 2014 May;52(3):563-583. doi: 10.1016/j.rcl.2013.12.001. Epub 2014 Jan 18. Review. PMID: 24792657 10. Margolis NE, Morley C, Lofti P, Shaylor SD, Palestrant S, Moy L, Melsaether AN. Update on the post-surgical breast: imaging the cutting edge techniques. Radiographics. 2014 May-Jun;34(3):642-60. doi: 10.1148/rg.343135059. PMID: 24819786

11. Moy L, Newell MS, Mahoney MC, Bailey L, Barke LD, Carkaci S, D'Orsi C, Goyal S, Haffty BG, Harvey JA, Hayes MK, Jokich PM, Lee SJ, Mainiero MB, Mankoff DA, Patel SB, Yepes MM. ACR Appropriateness Criteria stage I breast cancer: initial workup and surveillance for local recurrence and distant metastases in asymptomatic women. J Am Coll Radiol. 2014 Dec;11(12 Pt A):1160-8. doi: 10.1016/j.jacr.2014.08.020. Epub 2014 Oct 23. PMID: 25444069 12. Gillman, Toth HK, Moy L. Role of T1-Weighted Fat-Suppressed Screening Breast MRI in the High- Risk Population. Womens Health (Lond Engl). 2014 Nov;10(6):609-22. doi: 10.2217/whe.14.61. PMID: 25482488 13. Barke LD, Newell MS, Bailey L, Carkaci S, D’Orsi CJ, Haffty BG, Harvey JA, Hayes MK, Jokich PM, Lee SJ, Mainiero MB, Mankoff DA, Moy L, Patel SB, Yepes MM, Mahoney MC. ACR Practice Parameters for the Performance of Ultrasound-Guided Percutaneous Breast Interventional Procedures. http://www.acr.org/~/media/ACR/Documents/PGTS/guidelines/US_Guided_Breast.pdf 14. Lee SJ, Newell MS, Bailey L, Barke LD, Carkaci S, D’Orsi CJ, Haffty BG, Harvey JA, Hayes MK, Jokich PM, Lee SJ, Mainiero MB, Mankoff DA, Moy L, Patel SB, Yepes MM, Mahoney MC. ACR Practice Parameters for the Performance of Stereotactic-Guided Percutaneous Breast Interventional Procedures. http://www.acr.org/~/media/ACR/Documents/PGTS/guidelines/Stereotactically_Guided_Breast.pdf 15. Melsaether A, Pujara AC, Moy L. PET/MRI Breast. Siemens MAGNETOM Flash 2014 16. Mainiero MB, Lourenco AP, Barke LD, Argus AD, Bailey L, Carkaci S, D'Orsi C, Green ED, Holley SO, Jokich PM, Lee SJ, Mahoney MC, Moy L, Slanetz PJ, Trikha S, Yepes MM, Newell MS. ACR Appropriateness Criteria Evaluation of the Symptomatic Male Breast. J Am Coll Radiol. 2015 May 19. pii: S1546-1440(15)00187-8. doi: 10.1016/j.jacr.2015.03.024. PMID: 26001306 17. Moy L, McGinty G, Sickles EA. ACR Bulletin, 2015 18. Jokich PM, Newell MS, Bailey L, Barke L, Carkacci S, D’Orsi C, Green ED, Lee SJ, Mainiero MB, Moy L, Yepes M, Mahoney MC. ACR Appropriateness Criteria: Breast Pain. https://acsearch.acr.org/docs/3091546/Narrative/ 19. Lin D, Moy L, Axelrod D, Smith J. Utilization of MRI in Breast Cancer Screening. Current Oncology 2015 Oct;22(5):e332-5. doi: 10.3747/co.22.2882. No abstract available. PMID: 26628872 20. Rosenkrantz AB, Friedman K, Chandarana C, Melsaether AN, Moy L, Ding YS, Jhaveri K, Beltran L, Jain, R. Current status of hybrid PET/MR in oncologic imaging. AJR Am J Roentgenol. 2015 Oct 22:1-11. PMID: 26491894 21. Heller SL, Moy L. High Risk Screening with Breast MRI. Online and print DoRadiology.com. Section 2; in press 22. Albert M, Gao Y, Moy L. Role of Breast MRI in Patients with Newly Diagnosed Breast Cancer. Current Breast Cancer Reports (Volume 8, Issue 2 – June 2016), 1-10 DOI 10.1007/s12609-016-0205-8 23. Gao Y, Ibidapo O, Toth H, Moy L. Extramammary findings on breast MRI. Radiographics (in press)

Educationally Relevant Publications: 1. Moy L. Book Review – The Practice of Breast Ultrasound by Helmut Madjar, MD Menopause, The Journal of the North American Menopause Society, June 2000. 2. Moy L, Michaelson J, Sgroi D. Benign Breast Disease – An Overview. General Electric Web Site – Hersource.com, April 2000. 3. Moy L. Handbook for Mammography in-service for technologist. Massachusetts Society of Radiological Technologists (MRST), May 2000

4. Surgical Interactive Multimedia Modules (SIMMS) Developed on-line presentations pertaining to breast imaging for the BREAST CANCER SIMMS modules sponsored by the New York University Langone Medical Center- Surgery Department 2003 – 2004 5. ARRS Women’s Imaging Online Webcast: Clinical Applications of Breast MRI, September, 2007. 6. Sirrus Radio, What’s New in Breast Cancer Diagnosis and Treatment? Doctor’s Panel April 24, 2008 7. Moy L. “Breast MRI at 3.0 Tesla” – Society of Breast Imaging Newsletter Winter 2009 8. Contributor to ARRS Women’s Imaging Online – The Inside View March 2010 http://pqi.arrs.org/documents/Inside%20View%20Moy.pdf 9. Contributor to the following websites: Hersource.com, WebMD.com, Oncology.com, and Aunt Minnie.com. 10. “A New Kind of Cancer Probe: Advanced imaging techniques” Featured article in the NYU Physician; the magazine of NYU School of Medicine, Spring 2012 11. Moy L, Feig S“Current Status of Digital Breast Tomosynthesis” American Society of Breast Disease, Spring 2014, Advisor Issue 12. Freer P, Moy L, DeMartini W. ‘Breast Cancer Screening: Understanding the Randomized Controlled Trials”. SBI Newsletter 2015, Issue 3, p 13-14.

Books and Monographs 1. Mercado CL, Moy L. MRI Clinics of North America – Breast MRI. Co-Editor. Magn Reson Imaging Clin N Am, 2010, May;18(2):207-24, viii, 2010. 2. Heller SL, Moy L. Breast Oncology: Techniques, Indications, and Interpretations. Co-Editor, Springer, 2016

Other including Non-Print Materials None

Proceeding of Meetings 1. Raykar VC, Yu, S, Zhao LH, Jerebko A, Florin C, Hermosillo-Valadez G, Bogoni L, Moy L. Selected Learning from Multiple Experts: Whom to Trust when Everyone Lies a Bit. Proceedings of the 26th International Conference on Machine Learning, November 2009 2. Yan Y, Rosales R, Fung G, Schmidt, Hermosillo G, Bogoni L, Moy L, Dy J. Modeling annotator expertise: Learning when everybody knows a bit of something. JMLR Workshop and Conference Proceedings, Volume 9: AISTATS 2010. Proceedings of the Thirteenth International Conference on Artificial Intelligence and Statistics May 13-15, 2010, Chia Laguna Resort, Sardinia, Italy

Other including Non-Print Materials None

Proceeding of Meetings

1. Raykar VC, Yu, S, Zhao LH, Jerebko A, Florin C, Hermosillo-Valadez G, Bogoni L, Moy L. Selected Learning from Multiple Experts: Whom to Trust when Everyone Lies a Bit. Proceedings of the 26th International Conference on Machine Learning, November 2009 2. Yan Y, Rosales R, Fung G, Schmidt, Hermosillo G, Bogoni L, Moy L, Dy J. Modeling annotator expertise: Learning when everybody knows a bit of something. JMLR Workshop and Conference Proceedings, Volume 9: AISTATS 2010. Proceedings of the Thirteenth International Conference on Artificial Intelligence and Statistics May 13-15, 2010, Chia Laguna Resort, Sardinia, Italy

Abstracts (past three years, total 164 abstracts)

1. Melsaether AN, Plana N, Gillman J, Kim JA, Ibidapo O, Toth H, Moy L. The Effect of Tamoxifen on Background Parenchymal Enhancement, Fibroglandular Tissue and Mammographic Density. Proc. 114th ARRS, San Diego, 2014 2. Newburg A, Chhor C, Young Lin LL, Kim JA, Gillman J, Melsaether AN, Moy L. Breast MRI Nonmass Enhancement (NME): Review of BI-RADS MRI descriptors and imaging features. Proc. 114th ARRS, San Diego, 2014 3. Young Lin LL, Chhor C, Gillman J, Newburg A, Kim JA, Elias K, Moy L. Second-Look US in the Evaluation of MRI-Detected Lesions: How to Maximize Identification of Ultrasound Correlates. Proc. 114th ARRS, San Diego, 2014 4. Sigmund EE, Moy L, Kim JA, Kim S, Pujara AC, Amarosa A, Jhaveri K, Babb J, Geppert C, Glielmi C, Cho GY, Feiweier EE, Jackson K, Melsaether AN. Histogram analysis of intravoxel incoherent motion (IVIM)-MRI and FDG-PET parameters in breast cancer patients. Proc. 22th ISMRM, Milan, Italy 2014 5. Melsaether AN, Pujara AC, Pysarenko K, Raad RA, Ponzo F, Friedman K, Chandarana H, Jhaveri K, Sigmund EES, Kim S, Moy L. Whole body 18FDG-PET/MRI as compared with 18FDG-PET/CT in metastatic breast cancer. Proc. 22th ISMRM, Milan, Italy 2014 6. Pujara AC, Wassong C, Raad RA, Babb J, Moy L, Melsaether AN. Comparison of standardized uptake values in normal structures and breast cancer metastases using PET/CT and PET/MRI. Proc. 22th ISMRM, Milan, Italy 2014 7. Brown R, Geppert C, Moy L, Sodickson DK, Wiggins GC, Cloos MA. Bilateral Breast Imaging using Split-Symmetric Parallel Transmission. Proc. 22th ISMRM, Milan, Italy 2014 8. Cho GY, Zhang JL, Moy L, Baete S, Moccaldi M, Kim S, Sodickson DK, Sigmund EES. Comparison of fitting methods and b value sampling strategies for intravoxel incoherent motion (IVIM) in breast cancer. Proc. 22th ISMRM, Milan, Italy 2014 9. Margolis NE, Moy L, Pujara AC, Amarosa AR, Sigmund EES, Geppert C, Glielmi C, Freed M, Feng L, Otazo R, Melsaether AN, Kim S. Initial experience: combination of MR pharmacokinetic modeling and FDG uptake using simultaneous dynamic contrast enhanced MRI and PET imaging. Proc. 22th ISMRM, Milan, Italy 2014 10. Cho GY, Moy L, Klautau-Leite AP, Baete S, Babb J, Kim S, Sodickson DK, Sigmund EES. Intravoxel Incoherent Motion MRI for Tumor Subtype Differentiation in Locally Advanced Breast Cancer. Proc. 22th ISMRM, Milan, Italy 2014 11. Cho GY, Moy L, Klautau-Leite AP, Baete S, Babb J, Kim S, Sodickson DK, Sigmund EES. Breast Cancer Tumor Heterogeneity as Observed Using Intravoxel Incoherent Motion Histogram Analysis. Proc. 22th ISMRM, Milan, Italy 2014

12. Melsaether AN, Pujara AC, Sigmund EES, Amarosa AR, Schnabel F, Kiely D, Kim S, Moy L. Breast PET/MRI correlations between SUVmax, ADCmin, tumor markers and systemic disease. Proc. 22th ISMRM, Milan, Italy 2014 13. Jhaveri KL, Teplinsky E, Esteva FJ, Pujara A, Moy L, Melsaether AN. Detection of metastases in breast cancer: Is whole body PET/MR better than PET/CT? Proc. 50th ASCO, Chicago, IL 2014 14. Chun J, Schnabel F, Schwartz S, Billig J, Gillman J, Moy L. Mammographic breast density and magnetic resonance (MR) imaging in women with mammographically occult breast cancer. Proc. 2014 San Antonio Breast Cancer Symposium, San Antonio, Tx 2014. 15. Teplinsky E, Pujara A, Esteva FJ, Moy L, Melsaether A, Jhaveri K. Detection of Metastases in Breast Cancer: Is Whole Body PET/MR Better Than PET/CT? Proc ASCO Breast Cancer Symposium, San Franscisco, CA 2014 16. Dodelzon K, Chun J, Schwartz S; Kern E, Schnabel S, Moy L. Correlation between Magnetic Resonance Imaging characteristics and breast cancer Oncotype DX score. Proc. 100th RSNA, Chicago, 2014 17. Ego-Osuala IO, Elias K, Shaylor S, Albert ML, Toth HB, Moy L. Impact of Breast Density Notification Law in the Detection of Breast Cancer: Initial 15 Months Experience. Proc. 100th RSNA, Chicago, 2014 18. Newburg AR, Chhor CM,Young LY, Gillman J; Kim J; Toth HB, Moy L. Outcomes of breast MRI- detected suspicious non-mass enhancement (NME): Correlation with second-look ultrasound (US) and frequency of malignancy. Proc. 100th RSNA, Chicago, 2014 19. Sigmund E, Ostenson J, Moy L, Kim S, Cho G, Jhaveri K, Glielmi C, Feiweier T; Jackson K, Melsaether AN. Voxel-Wise Correlations of Glucose Uptake and Intra-voxel Incoherent Motion Parameters from simultaneous MR/PET in Locally Advanced Breast Cancer. Proc. 100th RSNA, Chicago, 2014 20. Heacock L, Melsaether AN, Pysarenko KM, Toth H, Moy L. Sensitivity of an Abridged Breast MRI Protocol to Detect Biologically Significant Breast Cancers. Proc. 100th RSNA, Chicago, 2014 21. Newburg AR, Chhor CM,Young LY, Gillman J; Kim J; Toth HB, Moy L. Diffuse non-mass enhancement (NME) may safely be categorized as background parenchymal enhancement. Proc. 100th RSNA, Chicago, 2014 22. Gillman J, Chun J, Schwartz S, Schnabel F, Moy L. The Relationship of Obesity, Mammographic Breast Density, and Magnetic Resonance Imaging Features in Patients with Breast Cancer. Proc. 100th RSNA, Chicago, 2014 23. Melsaether AN, Pujara AC, Raad,RA, Roberts J, Moy L. 18FDG-PET/MRI: Tutorial on Performance and Interpretation in Oncologic Patients. Proc. 100th RSNA, Chicago, 2014 24. Ego-Osuala IO, Elias K, Shaylor S, Albert ML, Toth HB, Moy L. Outcomes of Probably Benign Lesions Detected on Screening Ultrasound in Women with Average and High Risk: Are We Recommending Unnecessary Follow Up Exams? Proc. 100th RSNA, Chicago, 2014 25. Freed P, Storey P, Lewin A, Moccaldi M, Moy L, Kim S. Evaluation of lipid composition in the breast using multiple gradient echo MRI. Proc. ISMRM Workshop on Magnetic Resonance in Cancer: Challenges & Unmet Needs Austin Tx, 2014 26. Teurel J, Moy L, Kim JA, Kim S, Sigmund EE. Stimulated Echo Diffusion Tensor Imaging with Varying Diffusion Times as a Probe of Breast Tissue Length Scales. Proc. ISMRM Workshop on MRI in the Management of Breast Disease: Past, Present & Future, San Francsico, CA, 2015

27. Ostenson J, Moy L, Teruel J, Kim S, Melsaether A, Jhaveri K, Geppert C, Faul D, Esteva F, Adams S, Schnabel F, Jackson K, Lee J, Glielmi C, Cho GY, Feiweier T, Sigmund EE. Spatially Correlated Diffusion Weighted Imaging and 18-Fluorodeoxyglucose PET in Locally Advanced Breast Cancer. Proc. ISMRM Workshop on MRI in the Management of Breast Disease: Past, Present & Future, San Francsico, CA, 2015 28. Gillman G, Chun J, Schwartz S; Schnabel S, Moy L. Magnetic Resonance (MR) Imaging Screening and Mammographically Occult Breast Cancers. Proc. 115th ARRS, Toronto, CA 2015 29. Pinnamaneni N, Gillman J, Toth H, Moy L, Melsaether AN. Early and late effects of tamoxifen and aromatase inhibitors on background parenchymal enhancement and breast density. Proc. 115th ARRS, Toronto, CA 2015 30. Lee J, Chun K, Schnabel F, Schwartz S, Billig J, Moy L. Triple-negative tumor profile and its association with mammographic breast density, background parenchymal enhancement, and fibroglandular tissue pattern. Proc. 115th ARRS, Toronto, CA 2015 31. Gillman G, Chun J, Schwartz S; Schnabel S, Moy L. Imaging characteristics in a contemporary cohort of younger women with newly diagnosed breast cancer. Proceedings of the American Society of Breast Surgeons, Orlando, Fl 2015 32. Margolis NE, Lewin AA, Kim S, Moy L, Melsaether AN. Mammographically and sonographically occult lesions: MRI-DCE kinetic analysis. Proceedings of the SBI/ACR Breast Imaging Symposium Orlando, Fl 2015 33. Elias K, Ego-Osuala IO, Shaylor S, Albert ML, Toth HB, Moy L. Screening Ultrasound in Women with a History of a Prior High Risk Lesion, Should We Do It? Proceedings of the SBI/ACR Breast Imaging Symposium Orlando, Fl 2015 34. Pujara A, Raad R, Ponzo F, Wassong C, Babb J, Moy L, Melsaether AN. Standardized uptake values from PET/CT and PET/MRI in metastatic breast cancer: correlations and clinical implications. Proceedings of the SBI/ACR Breast Imaging Symposium Orlando, Fl 2015 35. Freed P, Storey P, Lewin A, Moccaldi M, Moy L, Kim S. Evaluation of lipid composition in patients with benign tissue and cancer using multiple gradient echo MRI. Proc. 23rd ISMRM, Toronto, Canada, 2015 36. Teurel JR,Cho GY, Ostenson J, Moccaldi M, Lee J, Kim SG, Moy L, Sigmund EE. Stimulated Echo Diffusion Tensor Imaging with Varying Diffusion Times as a Probe of Breast Tissue Cellularity. Proc. 23rd ISMRM, Toronto, Canada, 2015 37. Madelin G, Brown R, Moy L. Quantitative sodium breast MRI: a pilot study for estimating (pseudo) intracellular sodium concentration and extracellular volume fraction. Proc. 23rd ISMRM, Toronto, Canada, 2015 38. Ostenson J, Moy L, Kim SG, Melsaether A, Jhaveri K, Faul D, Cho GY, Glielei C, Geppert C, Lee J, Feiweier T, Jackson K, Sigmund EE. Intralesional Characteristics of Correlated 18-Fluorodeoxyglucose PET and Intravoxel Incoherent Motion Parameters in Locally Advanced Breast Cancer. Proc. 23rd ISMRM, Toronto, Canada, 2015 39. Lewin AA, Kim S, Babb J, Melsaether AN, McKellop J, Moccaldi M, Klautau Leite AP, Moy L. Assessment of Background Parenchymal Enhancement and Lesion Kinetics in Breast MRI of BRCA 1/2 Mutation Carriers Compared to Matched Controls. Proc. 23rd ISMRM, Toronto, Canada, 2015 40. Schnabel, Freya; Chun, Jennifer; Yeh, Janet; Schwartz, Shira; Rokosh, Sarah; Sure, Akhila; Snyder, Aki; Guth, Amber; Axelrod, Deborah; Moy, Linda. 'Imaging Characteristics in a Contemporary Cohort of

Younger Women with Newly Diagnosed Breast Cancer'. Annals of Surgical Oncology. 2015 22:101-101 (# 1788742) 41. Klautau Leite AP, Chammas M, Moy L. Young Women at High-Risk for Breast Cancer: Imaging characteristics (magnetic resonance, mammography and ultrasound). Proc. 101sth RSNA, Chicago, 2015 42. Geffen EV, Moy L. Breast Imaging for the Emergency Room Radiologist: An Educational Review. Proc. 101sth RSNA, Chicago, 2015 43. Seuss CR, Heller SL, Chun J, Schwartz S, Schnabel F, Moy L. Should Screening Breast MRI be Performed in Women with a History of Lobular Neoplasia? Proc. 101sth RSNA, Chicago, 2015 44. Gao Y, Toth HB, Moy L. Eyes Wide Open – Extramammary findings on breast MRI. Proc. 101sth RSNA, Chicago, 2015 45. Melsaether AN, Gao Y, Toth HB, Moy L. Abbreviated MRI of the Breast - Do We Need a Second Post-Contrast Scan? Proc. 101sth RSNA, Chicago, 2015 46. Heller SL, Jaglan S, Toth HB, Moy L. Frequency of Discordant Lesions and False Negative Cancers at Stereotactic Vacuum Assisted Biopsy. Proc. 101sth RSNA, Chicago, 2015 47. Seuss CR, Gao Y, Melsaether AN, Toth HB, Moy L. Prospective Abbreviated MRI Exam in a Screening Cohort Compared with Conventional Breast MRI. Proc. 101sth RSNA, Chicago, 2015 48. Gao Y, Freer PE, Moy L. Old tricks for a new dog? - Do strategies to detect subtle breast cancers on Full Field Digital Mammography work with Digital Breast Tomosynthesis. Proc. of the Society of Breast Imaging, Austin, Tx, 2016 49. Lewin AA, Heller SL, Jaglan S, Elias K, Newburg AR, Moy L. Radiologic-Pathologic Discordance and Outcomes After MR-Guided Vacuum Assisted Biopsy. Proc. of the Society of Breast Imaging, Austin, Tx, 2016 50. Cho GY, Gennaro L, Sutton E, Moy L, Sodickson DK, Morris EE, Sigmund EE, Thakur SB. Comparisons of pre- and post- treatment IVIM biomarkers to clinical response in breast cancer patients undergoing neoadjuvant chemotherapy. Proc. 24th ISMRM, Singapore, 2016 51. Bagadiya N, Heacock L, Gao Y, Jardon M, Heller S, Kim SG, Moy L. Does the Initial Enhancement Ratio (IER) Predict which Malignancies are Biologically Significant on a Pre-operative Breast MRI? Proc. 24th ISMRM, Singapore, 2016 52. Heacock L, Gao Y, Heller SL, Melsaether AN, Kim SG, Moy L. Comparison of Conventional DCE- MRI and a Novel Golden-Angle Radial Compressed-Sensing and Parallel Imaging Method for the Evaluation of Breast Lesion Conspicuity and Morphology. Proc. 24th ISMRM, Singapore, 2016 53. Kim SG, Sigmund EE, Moccaldi M, Moy L. Hormonal effect on time-dependent diffusion of the breast fibroglandular tissue. Proc. 24th ISMRM, Singapore, 2016

25 CURRICULUM VITAE ~ MARGARET M. SZABUNIO, MD, FACR

CONTENT ORGANIZATION

I. GENERAL INFORMATION Office Address, Email, Telephone, Fax Professional Licensure, Board Certification, Research Certification

II. EDUCATION Undergraduate, Professional/Graduate, Continuing

III. PROFESSIONAL EXPERIENCES

IV. ACADEMIC APPOINTMENTS Faculty, Visiting Professorships

V. HOSPITAL or CLINICAL APPOINTMENTS

VI. CONSULTING ACTIVITIES Local, State/Regional, National/International

VII. TEACHING ACTIVITIES University Faculty, Professional Faculty

VIII. ADVISING ACTIVITIES Student Advising, Directed Student Learning, Thesis & Dissertation, Referee for Academic Appointment, Promotion or Tenure

IX. ADMINISTRATIVE ACTIVITIES & UNIVERSITY SERVICE University, College, Medical Center, Department

X. SPECIAL ASSIGNMENTS

XI. HONORS & AWARDS

XII. PROFESSIONAL ACTIVITIES, PUBLIC SERVICE & PROFESSIONAL DEVELOPMENT Memberships, Positions Held, Advisory Groups, Review Panels, Editorial Boards, Journal Peer-Reviewing, Media Contributions, Professional Development

XIII. SPEAKING ENGAGEMENTS Local, State/Regional, National/International

XIV. RESEARCH & INTELLECTUAL CONTRIBUTIONS Publications, Abstract Presentations, Sponsored Research Projects, Grant & Contract Activities, Non-Sponsored Research Projects, Other Creative Activities

XV. OTHER ACTIVITIES

Margaret M. Szabunio, MD, FACR 5/25/2016

Date Prepared: May 25, 2016

CURRICULUM VITAE

MARGARET M. SZABUNIO, MD, FACR Professor, non-tenure track, Clinical Title Series Chief, Division of Women’s Radiology Department of Radiology Division of Women’s Radiology Professor, Clinical Title Series, Joint Appointment Department of Surgery Professor, Clinical Title Series, Joint Appointment Department of Biomedical Engineering University of Kentucky College of Medicine UK HealthCare

I. GENERAL INFORMATION

Office Address 800 Rose Street, HX314C Lexington, Kentucky 40536-0293

Email [email protected] Telephone 859-323-2416 Fax 859-257-4457

Professional Licensure

New York State Board for Medicine 06/1988-05/2006 174654 Florida Department of Health, Division of Medical Quality Assurance 12/1990-01/2012 ME57828 Kentucky Board of Medical Licensure 12/2010-03/2016 #43979

Drug Enforcement Agency Controlled Substance Registration 11/1986-12/2017 WITHHELD

Advanced Cardiac Life Support, Recertification 12/2014-04/2016 #H-4315 Basic Life Support, Recertification 12/2014-04/2016 #C-29385

Margaret M. Szabunio, MD, FACR 5/25/2016 2

I. GENERAL INFORMATION - cont

Board Certification

National Board of Medical Examiners 1985 Diplomate

American Board of Radiology 1990 Diplomate, Diagnostic Radiology 2013 Voluntary Participant, Lifetime Certificate Maintenance of Certification Program

Research Certification

Collaborative Institutional Training Initiative, Human Research Curriculum, Group 1 Biomedical Investigators and Key Personnel 08/2011-07/2014 Initial Completion Certificate, University of Kentucky 07/2014-07/2016 Refresher Completion Certificate, University of Kentucky

Margaret M. Szabunio, MD, FACR 5/25/2016 3

II. EDUCATION

Undergraduate

Hunter College, The City University of New York New York, New York 09/1973-06/1977 BA, Biology, magna cum laude

Professional/Graduate

Hahnemann University Medical School Philadelphia, Pennsylvania 08/1980-06/1984 MD

Post-Graduate

Presbyterian Hospital University of Pennsylvania Medical Center Philadelphia, Pennsylvania 07/1984-06/1985 Internal Medicine Internship

Long Island Jewish Medical Center New York, New York 07/1985-06/1989 Diagnostic Radiology Residency

Long Island Jewish Medical Center New York, New York 07/1989-06/1990 Body Imaging Fellowship

Continuing

Not Applicable

Margaret M. Szabunio, MD, FACR 5/25/2016 4

III. PROFESSIONAL EXPERIENCES

James A. Haley Veterans Hospital Department of Radiology Tampa, Florida 07/1990-09/2001 Staff Radiologist

H. Lee Moffitt Cancer Center and Research Institute Tampa, Florida 1993-2001 Part-time Breast Imager 2001-2010 Staff, Ultrasound & Breast Imager

University of Kentucky Medical Center Department of Radiology Lexington, Kentucky 01/2011- Faculty Radiologist, Division of Women’s Radiology

Margaret M. Szabunio, MD, FACR 5/25/2016 5

IV. ACADEMIC APPOINTMENTS

Faculty

University of South Florida College of Medicine Tampa, Florida 07/1990-07/2006 Assistant Professor of Radiology 05/2002-07/2006 Assistant Professor of Interdisciplinary Oncology 08/2006-10/2009 Associate Professor of Radiology 08/2006-12/2010 Associate Professor of Interdisciplinary Oncology 10/2009-12/2010 Associate Professor of Radiology with Tenure

University of Kentucky College of Medicine Lexington, Kentucky 01/2011- Professor of Radiology, Clinical Title Series, non-tenure track, full-time 01/2011- Professor of Surgery, Joint Appointment 03/2013- Professor of Biomedical Engineering, Joint Appointment

Visiting Professorships

Not Applicable

Margaret M. Szabunio, MD, FACR 5/25/2016 6

V. HOSPITAL or CLINICAL APPOINTMENTS

James A. Haley Veterans Hospital Department of Radiology Tampa, Florida 07/1990-09/2001 Staff Radiologist 07/1990-09/2001 Chief, Ultrasound Section

H. Lee Moffitt Cancer Center and Research Institute Tampa, Florida 1993-2001 Part-Time Breast Imager 2001-2010 Staff, Ultrasound & Breast Imager 09/2001-12/2010 Director, Diagnostic Ultrasound 09/2007-12/2010 Director, Breast Imaging

University of Kentucky Medical Center Department of Radiology, full-time Lexington, Kentucky 01/2011- Faculty Radiologist, Division of Women’s Radiology 01/2011- Associate Medical Director, Comprehensive Breast Care Center (CBCC) 01/2011- Chief, Division of Women’s Radiology

Primary Care Centers of Eastern Kentucky Hazard, Kentucky 02/2015- Attending Radiologist

Rockcastle Hospital and Respiratory Care Center, Inc. Mount Vernon, Kentucky 07/2015- Consulting Medical Staff, part-time

Margaret M. Szabunio, MD, FACR 5/25/2016 7

VI. CONSULTING ACTIVITIES

Local

Not Applicable

State/Regional

Not Applicable

National/International

Not Applicable

Margaret M. Szabunio, MD, FACR 5/25/2016 8

VII. TEACHING ACTIVITIES

University Faculty

University of South Florida, College of Medicine Tampa, Florida 1993-2010 Didactic Lectures in Ultrasound and Bone Radiology 1993-2010 Course Instructor - Diagnostic Radiology Elective (MEL 7704) 1997-2000 Coordinator & Moderator of Pathology / Radiology Correlation Conferences for Diagnostic Radiology Residents 1998-2001 Course Instructor - Abdominal Imaging (BMS 6810) 2001-2003 Weekly Clinical Interdisciplinary Conferences GU 2001-2010 Breast Imaging Radiology Lectures in Ultrasound of the Breast 2003-2010 Preceptor - Longitudinal Clinical Experience (BMS 6941) 2004-2010 Course Instructor - Profession of Medicine Content Expert (BMS 5007) 2006-2010 Course Instructor - Pathobiology of Human Cancer (GMS6334) 2007-2010 Clinic Supervisor - Interdisciplinary Oncology Clerkship (BCC8117)

H. Lee Moffitt Cancer Center & Research Institute Tampa, Florida 1990-2010 Diagnostic Radiology Resident Monthly Case Conferences 1993-2010 Diagnostic Radiology Residency Coordinator for Ultrasound 1995-2010 Sponsor for Residents’ Day Presentations 2003-2010 Weekly Clinical Interdisciplinary Conferences GYN 2006-2010 Weekly Clinical Interdisciplinary Conferences Breast Imaging

University of Kentucky College of Medicine University of Kentucky Medical Center Lexington, Kentucky 01/2011- Department Conferences for Radiology Residents & Fellows 01/2011-05/2013 Oral Board Reviews for Senior Radiology Residents 2011- Resident & Medical Student Education: Didactic Lectures and Case Conferences in Women’s Radiology 2011- Breast Cancer Workshop: MD 837 10/2013- Core Examination Board Reviews for 3rd- & 4th-Year Radiology Residents

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VII. TEACHING ACTIVITIES - cont

Professional Course/Program Faculty

First International Breast Imaging Diagnostic Course Warsaw, Poland 09/2001 “Clinical Image Evaluation and Mammographic Techniques and Positioning” 09/2001 “BI-RADS - The Mammography Report” 09/2001 “Indication for the Use of Different Types of Needle Biopsies” 09/2001 “Workshops: Ultrasound-Guided Procedures and Case Analysis”

Hot Topics in Oncology: Breast Cancer Tampa, Florida Co-Course Director: 02/2005 “Stereotactic Biopsy: New Techniques”

Annual Meeting of the American Roentgen Ray Society (ARRS) 2006-2008 “Approach to Diagnosis: A Case-Based Imaging Review, Breast Imaging: Ultrasound” 2010 “Approach to Diagnosis: A Case-Based Imaging Review, Breast Imaging: Ductal Pathology”

Annual Meeting of the Radiological Society of North America (RSNA) Chicago, Illinois 12/2008-12/2011 “Ultrasound-Guided Interventional Breast Procedures Workshop” 11/2012 “Refresher Course: The Post-Menopausal Patient: Controversies in Clinical and Radiological Care Lecture” 11/2012; 11/2013; 11/2014; 11/2015 “Refresher Course: Ultrasound-Guided Interventional Breast Procedures Hands-On Workshop”

University of Kentucky Family Medicine Review Course Lexington, Kentucky 11/2013 “Screening Mammography” 05/2014 “Screening Mammography”

Margaret M. Szabunio, MD, FACR 5/25/2016 10

VII. TEACHING ACTIVITIES - cont

Professional Course/Program Faculty

Department of Radiology University of Kentucky College of Medicine Lexington, Kentucky 01/2015 Hot Topics in Breast Imaging: Read with the Experts “BIRADS Update” “BIRADS 3: Multimodality Management” “Tomosynthesis: Case Presentations”

Margaret M. Szabunio, MD, FACR 5/25/2016 11

VIII. ADVISING ACTIVITIES

Student Advising

University of South Florida College of Medicine Tampa, Florida Annual Department of Radiology Residents’ Day Presentations: 1995 Thornton C. “The Radiographic Features of Eosinophilic Granuloma”. 1995 Wagner A. “Round Pneumonia: The Great Pretender”. 1996 Crocker D. “Cholelithiasis and Cholecystitis”. 1996 Raimondi R. “Neuropathic Joints”. 1997 Aguila S. “Thyroid Nodule: Role of Sonography” (Award presentation). 1998 Busby D. “Imaging Acute Renal Colic”. 1999 Parise J. “Urachal Cysts”. 2000 Fargher S. “Metastatic Renal Cancer Presenting as Submucosal Colonic Lesion”. 2000 Hurtado A. “Fournier’s Gangrene”. (Award presentation). 2000 Anderson S. “The Male Breast Mass: Discussion and Case Presentation”. 2001 Matti F. “Barium and the Beast (Adult Intussusception)”. 2003 Matti F. “Musculoskeletal Signs”. 2004 Pappas E. “Ultrasound Directed Transvaginal Biopsy and Aspiration of Pelvic Masses and Cysts”. 2004 Prakash N. “Ultrasound Diagnosis of Testicular Tumors”. 2005 Bailey C. “Thyroid Elastography”. (Award Presentation- 2nd Place) 2005 Portillo M. “Small Particle Disease”. 2005 Whitney L. “Transvaginal Ultrasound Guided Intervention”. 2006 Bailey C. “Imaging of Melanoma”. 2007 Saenz R. “Breast Sonoelastography”. 2007 Yokum M. “Case Study & Potential Usefulness of Testicular Biopsy”. 2008 Mooney B. “Triple Negative Breast Cancer, Imaging and Treatment”. 2008 Gierbolini J. “Ultrasound Evaluation of Lymph Nodes in Melanoma Patients, and the Prognostic Value for Detecting Metastatic Disease”. 2009 Tucker T. “Diagnostic Performance of Ultrasound Elastography in Differentiating Malignant and Benign Breast Lesions” (Runner-Up). 2009 Reed S. “PET and Thyroid Nodules” (First Place). 2010 Tucker T. “Final Diagnostic Performance Results of Ultrasound Elastography in the Evaluation of Breast Lesions”. 2010 Thomas K. “Final Diagnostic Performance Results of Ultrasound Elastography in the Evaluation of Breast Lesions”. 2010 D’Alessandro M. “Final Diagnostic Performance Results of Ultrasound Elastography in the Evaluation of Breast Lesions”. 2010 Koohi J. “Dual Ectopic Thyroid with Normally Located Thyroid Gland: A Case Report”.

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VIII. ADVISING ACTIVITIES - cont

Directed Student Learning

Not Applicable

Thesis & Dissertation

PhD Final Defense 07/2015 Lian He, Department of Biomedical Engineering

Invited Referee for Academic Appointment, Promotion or Tenure

Not Applicable

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IX. ADMINISTRATIVE ACTIVITIES & UNIVERSITY SERVICE

University

Not Applicable

College

University of South Florida Tampa, Florida

Education & Research 2007-2010 Coordinator, Breast Subspecialty, Residency Radiology Training Committee

University of Kentucky College of Medicine Lexington, Kentucky

Education & Research 07/2015- Member, Doctoral Advisory Committee 07/2015- Course Director, DR 815/DR 825 Introduction to Breast Imaging

Medical Center

University of South Florida Tampa, Florida

Administration & Clinical Operations 1999-2003 Faculty Council, Radiology Representative 2002-2003 Member, Strategic Planning Group, Radiology Representative 2003-2010 Member, Women’s Health Subgroup Committee for the New Health Education Building, Radiology Representative

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IX. ADMINISTRATIVE ACTIVITIES & UNIVERSITY SERVICE - cont

Medical Center - cont

H. Lee Moffitt Cancer Center and Research Institute Tampa, Florida

Administration & Clinical Operations 2007-2010 Member, Asset Investment Management Systems Committee 2007-2010 Member, Breast Program Task Force Committees Task Force 2: Breast Imaging Priority Implementation Task Force 3: Diagnostic Breast Clinic & Morsani Center Task Force 5: Multidisciplinary Conference 2008-2009 Member, Medical Executive Committee 2008-2010 Member, Appointments, Promotion & Tenure Committee 2008-2010 Member, Lifetime Cancer Screening Steering Committee 2009-2010 Member, Medical Staff Bylaws Committee

Education & Research 1993-2010 Member, Resident Training Committee 2004-2007 Member, Continuing Medical Education Advisory Committee 2007-2010 Director, Breast Imaging Fellowship Program 2007-2010 Director, Breast Imaging Education Program 2008-2010 Member, Graduate Medical Educational Committee

University of Kentucky Medical Center/UK HealthCare Lexington, Kentucky

Administration & Clinical Operations 2011- Consultant Radiologist, Breast Cancer Disease Team 2011- Associate Medical Director, Comprehensive Breast Care Center

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IX. ADMINISTRATIVE ACTIVITIES & UNIVERSITY SERVICE - cont

Department

University of South Florida Department of Radiology Tampa, Florida

Administration & Clinical Operations 1993-2010 Coordinator, Ultrasound Subspecialty Committee

Education & Research 1993-2010 Member, Residency Selection Committee

University of Kentucky Medical Center Department of Radiology Lexington, Kentucky

Administration & Clinical Operations 2011 Member, Operations Committee 2011-2012 Member, Quality, Safety & Compliance 2011-2012 Member, Imaging Technology Committee 2011-2013 Member, Executive Committee 2011- Site Supervising Physician, American College of Radiology (ACR) Mammography Accreditation and Reaccreditation 2011- The Joint Commission and Disaster Plan Unit Survey Response Administrator On-Call, Comprehensive Breast Care Center 2013- Member, Advisory Committee (f/k/a Executive Committee) 2015- Member, Scorecard WorkGroup

Education & Research 2011- Member, Education Committee 2011- Member, Research Committee 2013- Member, Continuing Medical Education Planning Committee 2013- Member, Women’s Radiology Subcommittee, Continuing Medical Education Committee 2016- Member, Women’s Executive Leadership Development Program

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X. SPECIAL ASSIGNMENTS

Not Applicable

Margaret M. Szabunio, MD, FACR 5/25/2016 17

XI. HONORS & AWARDS

1995-1999;2001; Outstanding Teacher Award, presented by University of South Florida 2003;2005 (USF) Radiology Residents 1997 Raphael A. Gomez Golden Apple Award for Teaching Excellence, presented by University of South Florida (USF) Senior Radiology Residents 04/2007 Certificate of Appreciation, Longitudinal Clinical Experience (LCE) Program, presented by University of South Florida (USF) Medical Students Class of 2009 2007 2007 America’s Top Radiologists, Consumers’ Research Council of America 2008 2008 Women of the Year in Medicine and Healthcare, presented by the American Biographical Institute 2009 Highest Honors for Presentation, Annual Meeting of the Florida Radiological Society 2010 Elected Fellow, American College of Radiology (ACR) 2016 Sarah Bennett Holmes Award, presented by the Women’s Forum Board

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XII. PROFESSIONAL ACTIVITIES, PUBLIC SERVICE & PROFESSIONAL DEVELOPMENT

Memberships

1990-2003 Florida West Coast Radiological Society 1990- American Association for Women Radiologists (AAWR) 1990- American College of Radiology (ACR) 1991- Radiological Society of North America (RSNA) 1997- American Roentgen Ray Society (ARRS) 1997-2011 Florida Radiological Society (FRS) 2001-2007 Society of Radiologists in Ultrasound (SRU) 2007- Society of Breast Imaging (SBI) 2011-2012 Bluegrass Radiological Society (BGRS)

Positions Held

Local Not Applicable

State/Regional

American Cancer Society Annual Fundraiser Tampa, FL 11/2008 Member, Cattle Baron’s Ball Committee

Florida Radiological Society Tampa, Florida 2009-2010 Co-Chair, Mammography Committee 2009-2010 Member, Ultrasound Committee

National/International

American Association for Women Radiologists (AAWR) 2004-2007 Member, Membership Committee 2007-2009 Member, International Committee 2008-2010 Member, Outreach Committee 2008-2012 Chair, Corporate Support Committee 2011-2014 Chair, Finance Committee 2011-2012 Director, Research & Education Foundation 2011-2014 Treasurer 2014-2015 Vice President 2015-2016 President Elect 2015- Member, Bylaws Committee 2015- Member, Program Committee

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XII. PROFESSIONAL ACTIVITIES, PUBLIC SERVICE & PROFESSIONAL DEVELOPMENT

National/International – cont

Society of Breast Imaging, American College of Radiology 2012-2014 Alternate Councilor 2014- Councilor 10/2015- Member, Membership Committee 03/2016- Member, Breast Imaging Fellowship Match Committee

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XII. PROFESSIONAL ACTIVITIES, PUBLIC SERVICE & PROFESSIONAL DEVELOPMENT - cont

Advisory Groups

Not Applicable

Review Panels

Videoconference Breast Cancer Tumor Boards with Bethesda Health Care, Martin Memorial, Stuart, FL, Parrish Medical Center, Titusville, FL, Moffitt Cancer Center and Research Institute, 2009-2010 Tampa, FL

Editorial Boards

Not Applicable

Journal Peer-Reviewing

02/2016 American College of Radiology Mammography Accreditation Program, Reviewer

Media Contributions

ABC Action News 05/2008 “Use of Sonograms in Detecting Breast Cancer”, Television, Linda Hurtado

CBS Action 10 News 02/2009 “Elastography as Part of Breast Ultrasound Examination and Potential Reduction of Benign Biopsies”, Television, Melissa Liberman

Channel 9 News 11/2009 “Mammography Age Controversy”, Television, Tampa, Florida

Jack Pattie Radio Show WVLK 10/2012 “Breast Imaging”, Radio, Interview and Answer Audience Questions, Lexington, Kentucky, Jack Pattie

Dr. A Show WCKY 1530 10/2012 “Breast Care and Cancer Treatment”, Radio, Cincinnati, Ohio, Dr. A

Dr. Greg Davis on Medicine, WUKY 10/2013 “Breast Cancer Awareness Month”, Radio, Lexington, Kentucky, Dr. Greg Davis

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XII. PROFESSIONAL ACTIVITIES, PUBLIC SERVICE & PROFESSIONAL DEVELOPMENT – cont

Media Contributions - cont

10/2015 WUKY “New ACS Mammography Guidelines”, Radio, Lexington, Kentucky, Karen Czarencky

10/2015 OZ Magazine “ACS Guidelines and Breast Health”, Magazine, Lexington, Kentucky, Florence Williams

Professional Development

American College of Radiology (ACR) 2013 Annual Meeting & Chapter Leadership Conference Washington, DC 05/2015; 05/2016 Annual Meeting, Washington, DC

National Conference on Breast Cancer 05/2014 Annual Conference, Phoenix, AZ

Radiological Society of North America (RSNA) 2008-2013 11/2014; 11/2015 Annual Meeting, Chicago, IL

Society of Breast Imaging (SBI) 2013 Postgraduate Course, Los Angeles, CA 04/2015 Annual Meeting, Orlando, FL

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XIII. SPEAKING ENGAGEMENTS

Local

H. Lee Moffitt Cancer Center and Research Institute Tampa, Florida 04/2010 “Moffitt Cancer Center Breast Cancer Update and Case Conference” Hematology/Medical Oncology Fellowship Teaching Conference: 11/2009 “Radiology Principles for Breast Cancer, Breast Cases” 03/2010 “Ultrasound of Thyroid Nodules” 03/2010 “Thyroid Disease: Beyond the Simple Nodule”

University of Kentucky Lexington, Kentucky Markey Research Seminar 09/2011 “Emerging Technologies in Breast Imaging” College of Nursing 2011 Homecoming Brunch 10/2011 “Early Diagnosis of Breast Cancer: Screening, Controversies & New Modalities” Advanced Medical Imaging Symposium 10/2011 “Tomosynthesis – 3D Mammography for the 21st Century” 02/2012 “Elastography” 04/2014 “Optical Imaging” Internal Medicine Grand Rounds 03/2013 “Breast Cancer Screening” Presentation to Commissioner Stephanie Mayfield 05/2013 “Mobile Mammography”

State/Regional

H. Lee Moffitt Cancer Center and Research Institute Tampa, Florda University of Florida Moffitt Women’s Cancer Collaboration Meeting: 08/2008 “Moffitt Cancer Imaging Program” University of Florida and Shands HealthCare Scientific Retreat: 08/2009 “Assessing Breast Cancer Risk by Diffuse Optical Tomography” Multidisciplinary Breast Cancer Symposium: 04/2010 “Breast Imaging Evaluation of Tumor Response in Patients Undergoing Neoadjuvant Chemotherapy”

Gulfcoast Ultrasound Institute St. Petersburg, Florida 04/2009 “Breast Elastography”

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XIII. SPEAKING ENGAGEMENTS - cont

State/Regional - cont

22nd Annual FACTors Breast Cancer Education Conference Tampa, Florida 09/2009 “Expert Panelist/Lunch with an Expert: Wild Flowers are True Survivors”

New Advances in Hematologic Oncology, Breast Cancer and Other Notable Advances Sarasota, Florida 10/2009 “Elastography of the Breast”

5th Annual Joining FORCEs Conference Orlando, Florida 06/2010 “Non-Surgical Approaches to Breast Cancer Risk Management/ Surveillance”

Annual Women It’s About You Lexington, Kentucky 04/2011 “Breast Cancer Basics” 06/2013 “Breast Imaging”

Horses and Hope Breast Cancer Survivor Luncheon Lexington, Kentucky 04/2011 “The Importance of Breast Cancer Screening” 04/2013 “The Importance of Breast Cancer Screening”

Fayette County Health Department Lexington, Kentucky 04/2012 “Staff Meeting, Lecture: CBCC Current and New Services”

Annual Primary Care for Women Update 2012 Lexington, Kentucky 10/2012 “Breast Imaging”

The Markey Cancer Center Affiliate Network Annual Meeting Lexington, Kentucky 04/2013 “Early Diagnosis of Breast Cancer”

Legends Ballpark Breast Cancer Awareness Dinner Lexington, Kentucky 07/2013 “Panel Speaker”

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XIII. SPEAKING ENGAGEMENTS - cont

State/Regional - cont

Kentucky Society of Nuclear Medicine Technologists Lexington, Kentucky Fall Educational Meeting: 10/2014 “Nuclear Medicine in Breast Imaging”

National/International

American Society of Abdominal Surgeons Tampa, Florida 16th Annual Gastrointestinal Surgery Conference: 01/1991 “Current Imaging of Pancreatic Disease”

Great American Teaching Middle & High School Medical Profession Lecture Tampa, Florida 2000-2008 “What It’s Like to Be a Radiologist”

Breast Imaging Update Key West, Florida 05/2003 “Sonographic Examination and Screening” 05/2003 “Improving Technique/Passing MQSA” 04/2005 “Breast Sonography and Screening” 04/2005 “Stereotactic Core Needle Biopsy” 04/2007 “Breast Sonoelastography” 04/2007 “Imaging Implants” Sarasota, Florida 05/2006 “Imaging Implants” 05/2006 “Breast Sonography and Screening”

Leading Edge in Diagnostic Ultrasound Annual Conference Atlantic City, New Jersey 05/2008 “Breast Elastography”

Endocrine Tumor Conference: Advances in Imaging Orlando, Florida 11/2008 “Diagnosing and Treatment; Sonography of Thyroid Nodules”

American Institute of Ultrasound in Medicine (AIUM) New York, New York 04/2009 “Elastography Applications in the Thyroid” San Diego, California 03/2010 “Clinical Applications of Elastography”

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XIII. SPEAKING ENGAGEMENTS - cont

National/International - cont

American Association for Women Radiologists (AAWR) Meeting at 95th Scientific Assembly and Annual Meeting of the Radiological Society of North America (RSNA) Chicago, Illinois 11/2012 “Considering a Subspecialty Practice in Breast Imaging & Interventions?” 11/2012 “Weighing an Academic Career vs. Private Practice”

Bard Peripheral Vascular & Bard Biopsy National Sales Meeting Scottsdale, Arizona 01/2016 “Stereotactic and Tomosynthesis Guided Vacuum-Assisted Biopsies”

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XIV. RESEARCH & INTELLECTUAL CONTRIBUTIONS

A. PUBLICATIONS

Peer-Reviewed Original Research in Professional, Scientific or Educational Journals

1. Michl J, Pieczonka MM, Unkeless JC, Silvertein SC. Effects of Immobilized Immune Complexes on Fc and Complement Receptor Function in Resident and Thioglycollate- elicited Mouse Peritoneal Macrophages. J Exp Med. 1979 Sep 19;150(3):607-21. 2. Michl J, Unkeless JC, Pieczonka MM, Silverstein SC. Modulation of Fc Receptors of Mononuclear Phagocytes by Immobilized Antigen-Antibody Complexes. Quantitative Analysis of the Relationship Between Ligand Number and Fc Receptor Response. J Exp Med. 1983 Jun 1;157(6):1746-57. 3. Michl J, Pieczonka MM, Unkeless JC, Bell GI, Silverstein SC. Fc Receptor Modulation in Mononuclear Phagocytes Maintained on Immobilized Immune Complexes Occurs by Diffusion of the Receptor Molecule. J Exp Med. 1983 Jun 1;157(6):2121-39. 4. Wagner AL, Szabunio MM, Hazlett K, Wagner S. Radiologic Manifestations of Round Pneumonia in Adults. AJR Am J Roentgenol. 1998 Mar;170(3):723-6. 5. Keehn CA, Seigne JD, Wade M, Szabunio MM, Ahmad N. Case Report: PET Scan Detects Prostate Cancer in a Patient with Hodgkin’s Lymphoma. Ann Clin Lab Sci. 2003;33(3):324- 5. 6. Cox CE, Furman B, Stowell N, Ebert M, Clark J, Dupont E, Shons A, Berman C, Beauchamp J, Gardner M, Hersh M, Venugopal P, Szabunio MM, Cressman J, Diaz N, Vrcel V, Fairclough PA-C. Radioactive Seed Localization Breast Biopsy and Lumpectomy: Can Specimen Radiographs Be Eliminated? Ann Surg Oncol. 2003 Nov;10(9):1039-47. 7. Kallergi M, Berman CG, Cressman JB, Loeffler WE, Romilly AP, Szabunio MM, Vedam PV, Venugopal PR, Walker JK. Clinical Evaluation of a New Digitizing Device for Improved Film Mammography. Acad Radiol. 2004 Nov; 11(11):1242-50. 8. Kallergi M, Bradley JL, Berman CG, Hersh MR, Pharm D, Szabunio MM, Clark R. High- Performance Wavelet Compression for Mammography: Localization Response Operating Characteristic Evaluation. Radiology. 2005 Jan; 238(1):62-73. 9. Naghashpour M, Cualing H, Szabunio MM, Bui M. Hyaline-Vascular Castleman Disease: A Rare Cause of Solitary Subcutaneous Soft Tissue Mass. Am J Dermatopathol. 2010 May;32(3):293-7. 10. Anderson L, Middleton WD, Teefey SA, Reading CC, Langer JE, Desser T, Szabunio MM, Hildebolt CF, Mandel SJ, Cronan JJ. Hashimoto Thyroiditis: Part 1, Sonographic Analysis of the Nodular Form of Hashimoto Thyroiditis. AJR Am J Roentgenol. 2010 Jul;195(1):208-15. 11. Anderson L, Middleton WD, Teefey SA, Reading CC, Langer JE, Desser T, Szabunio MM, Mandel SJ, Hildebolt CF, Cronan JJ. Hashimoto Thyroiditis: Part 2, Sonographic Analysis of Benign and Malignant Nodules in Patients with Diffuse Hashimoto Thyroiditis. AJR Am J Roentgenol. 2010 Jul; 195(1):216-22. 12. Kumm TR, Szabunio MM. Elastography for the Characterization of Breast Lesions: Initial Clinical Experience. Cancer Control. 2010 Jul; 17(3):156-61.

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XIV. RESEARCH & INTELLECTUAL CONTRIBUTIONS - cont

A. PUBLICATIONS - cont

Peer-Reviewed Original Research in Professional, Scientific or Educational Journals - cont

13. Chai C, Zager J, Szabunio MM, Marzban S, Chau A, Rossi R, Sondak V. Preoperative Ultrasound is Not Useful for Identifying Nodal Metastasis in Melanoma Patients Undergoing Sentinal Node Biopsy: Preoperative Ultrasound in Clinically Node-Negative Melanoma. Ann Surg Oncol. 2012;19(4):1100-6. 14. Li T, Lin Y, Shang Y, He L, Huang C, Szabunio MM, Yu G. Simultaneous Measurement of Deep Tissue Blood Flow and Oxygenation Using Noncontact Diffuse Correlation Spectroscopy Flow-Oximeter. Sci Rep. 2013;3:1358-60. 15. Williams M, Eatrides J, Kim J, Talwar H, Esposito N, Szabunio MM, Ismail-Khan R, Kiluk J, Lee M, Laronga C, Khakpour N. Comparison of Breast Magnetic Resonance Imaging Clinical Tumor Size with Pathologic Tumor Size in Patients Status Post- Neoadjuvant Chemotherapy. Am J Surg. 2013; 206(4):567-73. 16. He L, Lin Y, Huang C, Irwin D, Szabunio M, Yu G. Noncontact Diffuse Correlation Tomography of Human Breast Tumor. J Biomed Opt. 2015 Aug;20(8):86003-4. 17. Huang C, Lin Y, He L, Irwin D, Szabunio MM, Yu G. Alignment of Sources and Detectors on Breast Surface for Noncontact Diffuse Correlation Tomography of Breast Tumors. Appl Opt. 2015 Oct;54(29):8808-16.

Non-Peer-Reviewed Articles, Editorials, Reviews in Professional, Scientific or Educational Journals

Not Applicable

Books, Book Chapters, Monographs

1. Szabunio MM. Breast Imaging: Breast Ultrasound. In: American Roentgen Ray Society, ed. Approach to Diagnosis: A Case-Based Imaging Review. Leesburg, VA: ARRS; 2006:7-12.

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XIV. RESEARCH & INTELLECTUAL CONTRIBUTIONS - cont

A. PUBLICATIONS - cont

Letters, Book Reviews, Lay Press

Not Applicable

Electronic Media

Not Applicable

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XIV. RESEARCH & INTELLECTUAL CONTRIBUTIONS - cont

B. PRESENTATIONS

Local/State/Regional Meetings

1. July 2009. Tucker, T, Chau, A, Kumm, T, Szabunio MM. Diagnostic Performance of Color Elastography Scoring and Strain Ratio Assessment in the Evaluation of Breast Lesions: Initial Experience at a Single Cancer Referral Center. Annual Meeting of the Florida Radiological Society, Palm Beach, FL. Podium. Won Highest Honors 2. April 2013. Huang C, Lin Y, He L, Shang Y, Irwin D, Szabunio MM, Yu G. Noncontact Diffuse Optical 3-D Imaging of Hemodynamic Contrasts in Breast Tumor: Geometrical Reconstruction and Alignment of Optical Sources and Detectors. Markey Cancer Center Research Day, Lexington, KY. Podium. 3. April 2013. He L, Lin Y, Huang C, Irwin D, Szabunio MM, Yu G. Noncontact Diffuse Optical 3-D Imaging of Hemodynamic Contrasts in Breast Tumor: Computer Simulation. Markey Cancer Center Research Day, Lexington, KY. Podium. 4. April 2013. Lin Y, Li T, Shang Y, He L, Huang C, Szabunio MM, Yu G. Simultaneous Measurement of Deep Tissue Blood Flow and Oxygenation Using Noncontact Diffuse Correlation Spectroscopy Flow-Oximeter. Markey Cancer Center Research Day, Lexington, KY. Podium. 5. June 2015. Luna A, Theinert B, Douglass C, Hardy P, Szabunio M. Adjusting the Magnetic Field for Improved Dynamic Breast MRI. 2nd Annual Department of Radiology Quality & Safety Forum, University of Kentucky, Lexington, KY. Poster.

National/International Meetings

1. November 2003. Eikman EA, Szabunio MM, Murphy N, Beauchamp J. Mammography: Practice-Based Education with Proficiency Audit. Annual Meeting of Radiological Society of North America, Chicago, IL. Poster. 2. November 2003. Romilly AP, Kallergi M, Berman CG, Cressman JB, Szabunio MM, Venugopal P. Pilot Clinical Evaluation of a New Digital System for Mammography. Annual Meeting of Radiological Society of North America, Chicago, IL. Poster. 3. December 2006. Wagner A, Szabunio MM, Hazlett K, Miller M. Radiographic Manifestations of Round Pneumonia in Adults. Annual Meeting of Radiological Society of North America, Chicago, IL. Podium. 4. March 2008. Luo P, Szabunio MM, White J. Interactivity in Technology-Enhanced Mammogram Reading Instruction. American Educational Research Association, New York, NY. Podium. 5. May 2009. Kumm T, Szabunio MM. Characterization of Breast Lesions with Ultrasound Elastography. Annual Meeting of Association of University Radiologists, Arlington, VA. Scientific Poster.

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XIV. RESEARCH & INTELLECTUAL CONTRIBUTIONS - cont

B. PRESENTATIONS - cont

National/International Meetings - cont

6. September 2009. Kumm T, Chau A, Szabunio MM. Diagnostic Performance of Freehand Elastography with Strain Ratio Measurement in the Characterization of Breast Lesions Referred for Ultrasound-Guided Biopsy: Initial Clinical Results at a Single Cancer Referral Center. International Conference on the Ultrasonic Measurement and Imaging of Tissue Elasticity, Vlissingen, Zeeland, The Netherlands. Poster and Podium. 7. March 2010. Chai CY, Sondak VK, Zager JS, Szabunio MM, Marzban S, Rossi RM. Preoperative Ultrasound is Not Useful for Identifying Nodal Metastasis in Melanoma Patients Undergoing Sentinel Lymph Node Biopsy. Annual Cancer Symposium of Society of Surgical Oncology, St. Louis, MO. Poster. 8. March 2010. Kumm T, Grajo J, Chau A, Tucker T, Szabunio MM. Sensitivity and Specificity of Breast Sonoelasticity Imaging Utilizing Color Elastography and Strain Ratio Measurements. European Congress of Radiology, Vienna, Austria. Poster. 9. May 2010. Kumm T, Szabunio MM. Lesions Referred for Breast Biopsy: Combined Use of Color Elastogram and Strain Ratio Assessment. Annual Meeting of American Roentgen Ray Society, San Diego, CA. Electronic Exhibit. 10. July 2012. Zhang J, Garner W, Schlenker G, Szabunio MM. Digital Breast Tomosynthesis: Is the Room Shielding a Need? Annual Meeting of American Association of Physicists in Medicine, Charlotte, NC. Podium. 11. November 2012. Spicer PJ, Koerber A, Gibbs RD, Szabunio MM, Dell CM, True J. The Many Faces of Triple Negative Breast Cancer. Annual Meeting of Radiological Society of North America, Chicago, IL. Electronic Exhibit. 12. July 2014. Zhang J, Szabunio MM. Mammography Imaging: Does Positioning Matter? Annual Meeting of American Association of Physicists in Medicine, Austin, TX. Podium. 13. November 2014. Zhang J, Luna AY, Szabunio MM. Relationship Between Positioning, Radiation Exposure, Imaging Quality and the Effects on Diagnosis for Breast Imaging. Annual Meeting of Radiological Society of North America, Chicago, IL. Educational Exhibit. 14. October 2015. Lian H, Yu L, Huang C, Irwin D, Szabunio M, Yu G. Noncontact Diffuse Correlation Tomography of Human Breast Tumor. Annual Meeting of Biomedical Engineering Society (BMES), Tampa, FL. Podium.

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XIV. RESEARCH & INTELLECTUAL CONTRIBUTIONS - cont

C. SPONSORED RESEARCH PROJECTS, GRANT & CONTRACT ACTIVITIES

Active

Not Applicable

Inactive

Project Title: Digital vs. Screen-Film Mammography (DMIST) Project Number: n/a Principal Investigator(s): Etta Pisano, MD Role in Project: Co-I Effort: n/a Institution/University: n/a Source of Funding: ACRIN 6652 Total Award: n/a Grant Number: n/a Duration of Project: 03/01/2003-12/31/2004

Project Title: Survey of Utility of Diagnostic Imaging Project Number: n/a Principal Investigator(s): Edward Eikman, MD Role in Project: Co-I Effort: n/a Institution/University: n/a Source of Funding: MCC Total Award: n/a Grant Number: n/a Duration of Project: 03/2003- 03/2010

Project Title: A Multicenter Trial for Microarray Analysis of Colon Cancer Outcome-A (MACCO-A) Project Number: n/a Principal Investigator(s): Jonathan Strosberg, MD Role in Project: n/a Effort: n/a Institution/University: n/a Source of Funding: NCI R21 CA10135 Total Award: n/a Grant Number: n/a Duration of Project: 10/31/2003-12/2010

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XIV. RESEARCH & INTELLECTUAL CONTRIBUTIONS - cont

C. SPONSORED RESEARCH PROJECTS, GRANT & CONTRACT ACTIVITIES - cont

Inactive – cont

Project Title: Combination of External Beam Radiation with Intratumoral Injection of Dendritic Cells as Neo-adjuvant Treatment of High- Risk Soft Tissue Sarcoma Project Number: n/a Principal Investigator(s): Scott Antonia, MD Role in Project: Co-I Effort: n/a Institution/University: n/a Source of Funding: Cancer Treatment Research Foundation (CTRF) Total Award: n/a Grant Number: G-04-066 Duration of Project: 03/2006-02/2009

Project Title: A Phase II, Open Label, Single Arm, “Proof of Concept” Study of Tnferade Plus Radiation in Patients with Metastatic Melanoma Project Number: n/a Principal Investigator(s): Vernon Sondak, MD Role in Project: Co-I Effort: n/a Institution/University: n/a Source of Funding: GenVec Total Award: n/a Grant Number: GV-001.008 Duration of Project: 03/2006-03/2008

Project Title: A Multi-Institutional Analysis of Clinical and Ultrasound Features of Benign and Malignant Thyroid Nodules Project Number: n/a Principal Investigator(s): William Middleton, MD Role in Project: Co-I Effort: n/a Institution/University: n/a Source of Funding: University of Washington/Society of Radiologists in Ultrasound Total Award: n/a Grant Number: n/a Duration of Project: 05/2007-12/2010

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XIV. RESEARCH & INTELLECTUAL CONTRIBUTIONS - cont

C. SPONSORED RESEARCH PROJECTS, GRANT & CONTRACT ACTIVITIES - cont

Inactive – cont

Project Title: Dendritic Cell Vaccination During Lymphoid Reconstruction. Subtitle: A Dose-Ranging Trial of MART- 1/gp100/Tyrosinase/NY-ESO-1 Peptide-Pulsed Dendritic Cells Matured Using Cytokines with Autologous Lymphocyte Infusion With or Without Escalating Doses of Fludarabine for Patients with Chemotherapy-naïve Metastatic Melanoma - Phase I trial Project Number: n/a Principal Investigator(s): Jeffrey Weber, MD Role in Project: Co-I Effort: n/a Institution/University: n/a Source of Funding: MCC, USC, NCI 6241 Total Award: n/a Grant Number: n/a Duration of Project: 08/2007-12/2010

Project Title: A Phase I, Multicenter, Open Label, Clinical Trial of Immune Response, Safety and Tolerability of DNA Vector pPRA-PSM with Synthetic Peptides E-PRA and E-PSM in Subjects with Advanced Solid Malignancies Project Number: n/a Principal Investigator(s): Jeffrey Weber, MD Role in Project: Co-I Effort: n/a Institution/University: n/a Source of Funding: Mannkind Corp Total Award: n/a Grant Number: MKC1106-PP-001 Duration of Project: 10/2007-12/2010

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XIV. RESEARCH & INTELLECTUAL CONTRIBUTIONS - cont

C. SPONSORED RESEARCH PROJECTS, GRANT & CONTRACT ACTIVITIES - cont

Inactive - cont

Project Title: A Phase 1/2, Open Label, Non-Randomized Dose Escalation Study to Evaluate the Safety, Tolerability, Immune Response and Clinical Response of Multiple Doses of MKC1106-MT in Subjects with Advanced Melanoma Project Number: n/a Principal Investigator(s): Jeffrey Weber, MD Role in Project: Co-I Effort: n/a Institution/University: n/a Source of Funding: Mannkind Corp Total Award: n/a Grant Number: MKC1106-MT-001 Duration of Project: 06/2008-12/2010

Project Title: 3-D Ultrasound for Assessment of Treatment Effect in Neo- adjuvant Breast Cancer Patients: a Phase II Trial Project Number: n/a Principal Investigator(s): Catherine Lee, MD Role in Project: Co-I Effort: n/a Institution/University: n/a Source of Funding: Moffitt Foundation Grant Total Award: n/a Grant Number: n/a Duration of Project: 2008-2010

Project Title: Feasibility of Sonoelastography in the Characterization of Breast Nodules Project Number: n/a Principal Investigator(s): Margaret Szabunio, MD Role in Project: PI Effort: n/a Institution/University: n/a Source of Funding: MCC Total Award: n/a Grant Number: n/a Duration of Project: 09/2008-12/2010

Margaret M. Szabunio, MD, FACR 5/25/2016 35

XIV. RESEARCH & INTELLECTUAL CONTRIBUTIONS - cont

C. SPONSORED RESEARCH PROJECTS, GRANT & CONTRACT ACTIVITIES - cont

Inactive - cont

Project Title: A Retrospective Study to Correlate Treatment Response & Outcomes to Clinicopathologic & Molecular Phenotypes in Breast Cancer Patients Project Number: n/a Principal Investigator(s): Eleanor Harris, MD Role in Project: Co-I Effort: n/a Institution/University: n/a Source of Funding: n/a Total Award: n/a Grant Number: n/a Duration of Project: 05/2010-12/2010

Project Title: Non-Contact Diffuse Optical Quantification of Hemodynamic Contrast in Breast Tumor Project Number: IRB# 11-0576-F1V Principal Investigator(s): Guoqiang Y, PhD Role in Project: Co-I Effort: n/a Institution/University: n/a Source of Funding: CCTS Total Award: n/a Grant Number: n/a Duration of Project: 08/11/2011-04/03/2014

Project Title: Effect of Preoperative Breast MRI on Surgical Outcomes, Costs and Quality of Life of Women and Breast Cancer Project Number: IRB# 13-0771-F3R Principal Investigator(s): Heather Wright, MD Role in Project: Co-I Effort: n/a Institution/University: University of Kentucky Medical Center Source of Funding: ACRIN Total Award: n/a Grant Number: n/a Duration of Project: 10/14/2014-01/08/2015

Margaret M. Szabunio, MD, FACR 5/25/2016 36

XIV. RESEARCH & INTELLECTUAL CONTRIBUTIONS - cont

D. NON-SPONSORED RESEARCH PROJECTS

Active

Project Title: The Benefits of Using Audience Response System Technology in the Education of Radiology Residents Project Number: IRB# 13-0472-X4B (exempt status) Principal Investigator(s): M Elizabeth Oates, MD Role in Project: Co-I Institution/University: University of Kentucky Medical Center Duration of Project: 08/07/2013-08/06/2019

Project Title: RESOLVE: Diffusion Weighted Imaging for Characterizing Tumors Project Number: IRB# 14-0692-F2L Principal Investigator(s): Rashmi Nair, MD Role in Project: Co-I Institution/University: University of Kentucky Medical Center Duration of Project: 10/07/2014-07/31/2017

Inactive

Not Applicable

Margaret M. Szabunio, MD, FACR 5/25/2016 37

XIV. RESEARCH & INTELLECTUAL CONTRIBUTIONS - cont

E. OTHER CREATIVE ACTIVITIES

Not Applicable

Margaret M. Szabunio, MD, FACR 5/25/2016 38

XV. OTHER ACTIVITIES

Not Applicable

END OF DOCUMENT

Margaret M. Szabunio, MD, FACR 5/25/2016 39

LORA D. BARKE, D.O. Office: Invision Sally Jobe • 8200 E. Belleview Avenue, Ste 200E • Greenwood Village, CO 80111 Work: (720) 493-3220 Mobile: (303) 717-1574 Work Email: [email protected]

Current Position Radiologist (Partner) - Radiology Imaging Associates, Englewood, CO 1/2007-present

Board Certification Certificate in Diagnostic Radiology, American Board of Radiology 6/2003-present Maintenance of Certification (MOC) 8/2013-present

Education Fellowship Northwestern University Feinberg School of Medicine 7/2003-6/2004 Breast and Women’s Imaging Northwestern Memorial Hospital Department of Radiology Lynn Sage Comprehensive Breast Center Chicago, IL Residency Cook County Hospital 7/1999-6/2003 Diagnostic Radiology Chief Resident – 5/2001-6/2003 Chicago, IL Residency Cook County Hospital 7/1998-6/1999 Internal Medicine PGY2 Chicago, IL Internship Cook County Hospital 7/1997-6/1998 Transitional internship and Internal Medicine PGY1 Chicago, IL D.O. Midwestern University/ 8/1993-6/1997 Chicago College of Osteopathic Medicine Downers Grove, IL B.A. University of Iowa 8/1986-6/1990 Exercise Science Iowa City, IA

Faculty Academic Appointments Northwestern University Feinberg School of Medicine 7/2004-11/2006 Associate Professor, Department of Radiology, Breast Imaging Section Lynn Sage Comprehensive Breast Center Northwestern Memorial Hospital Department of Radiology Chicago, IL

Clinical/Hospital Appointments

Prepared 02/09/16 Lora D. Barke, D.O. - Page | 2

Invision Sally Jobe Breast Centers, Greenwood Village, CO 6/2009-present . Medical Director Radiology Imaging Associates, Englewood, CO 6/2009-present . Section Chief, Breast Imaging Aspen Valley Hospital, Aspen, CO . Medical Director, Breast Imaging 9/2010-9/2015 . Medical Director, Radiology 5/2010-5/2013

Committee Service American College of Radiology . Vice-Chair, Breast Imaging Practice Parameters 2014-present . Committee on Breast Ultrasound Accreditation - Q&S, 2013-present . Committee on Parameters and AC - Breast Imaging 2013-present . Subcommittee on Quality Assurance in Mammography 2013-present . Breast MRI Accreditation Committee Member & Reviewer 2011-present . Breast Ultrasound Accreditation Committee Member & Reviewer 2011-present HealthOne Breast Program Leadership . Breast Marketing Workgroup 2013-present . Breast Steering Committee 2012-present Centrum Surgical Center . Governing Board Member 2011-present Sky Ridge Medical Center . Breast Steering Committee 2011-present Susan G. Komen . Executive Committee 2011-present . Vice President, Board Member - Mission Initiative Committee 2011-present . Doctors for the Cure Advisory Board 2010-2014 . Grant Review Board 2010-2011 Radiology Imaging Associates (RIA) . Interview Committee 2015-present . Innovation Committee 2015-present . Practice Standards Committee 2009-present . Breast Imaging Committee 2007-present . Board of Directors 2011-2013 . Clinical Research Group 2010-2013 . Operations Committee 2010-2013 . Outpatient Committee 2007-2009 . Business Development Committee 2008 Institute of Medicine’s National Cancer Policy Forum . ACS Assessing and Improving the Interpretation of Mammograms 2014-2015 Workshop Planning Committee Aspen Valley Hospital 2011-2013 . Clinical Integration Committee Mammography Reporting System Lora D. Barke, D.O. - Page | 3

Medical Advisory Board 2010-2011

Professional Societies . National Accreditation Program for Breast Centers 2014-present . Society of Breast Imaging 2009-present . National Consortium of Breast Centers 2008-present . Colorado Radiological Society 2007-present . American College of Radiology 1999-present . American Roentgen Ray Society 1999-present . Radiologic Society of North America 1999-present

Report of Clinical Activities and Innovations Licensure and Certification Current . Colorado Medical License ▪ Illinois Medical License ▪ Nebraska Medical License . Hawaii Medical License ▪ Kansas Medical License

. Collaborative Institutional Training Initiative (CITI) Research Training 2/2016 . Advanced Cardiac Life Support / Basic Life Support Certified 4/2011 . Breast Tomosynthesis Certified 2/2010 . MammoSite Certified (Radiation Therapy System) 3/2005 . Full-Field Digital Mammography Certified 7/2003 . Board Certified in Diagnostic Radiology 6/2003

Practice Activities . Invision Sally Jobe Breast Centers Medical Director . Radiology Imaging Associates Breast Section Chief . Oversee Risk Assessment & Prevention Program . Lead Radiology Imaging Associates Breast Committee Meetings . Breast imaging, diagnostics, and general radiology . Advanced breast imaging techniques including tomosynthesis (3D Mammography), MRI, and Screening Breast Ultrasound . Performing breast biopsies, needle localizations, sentinel node injections, cyst aspirations, ductograms, clip and gold seed placements . Leading faculty member of “Mastering Breast Biopsy” Radiologist Training Course - in partnership with Bard Biopsy . Active advocate for early detection and prevention of breast cancer and personalized breast cancer screening and risk assessment

Clinical Research

. Retrospective MRI Completion Assessment of a Method to Inform Women about their 2014-present Personal Lifetime Risk of Breast Cancer and the ACS’s Guidelines for Additional Breast MRI Screening

. SenoPIONEER Study A Pivotal Study of Imaging with Opto-acoustics to Diagnose Lora D. Barke, D.O. - Page | 2

2013-2015 Breast Masses Detected by Mammography and/or Clinical Findings: A New Evaluation Tool for Radiologists

. Tomosynthesis Collaborative Performance Measures Assessment before and after 2011-present Introduction of Breast Tomosynthesis in the Screening Environment

. 10K Case Collection Protocol for Research, Development and 2010-2014 Testing of Full-field Digital Mammography, Digital Breast Tomosynthesis and Computer-Aided Algorithms and User Training

. Digital Breast Tomosynthesis A Multicenter, Controlled Clinical Trial to Evaluate the 2009-2012 Hologic Tomosynthesis Mammography System

. Bayer GEMMA Protocol 91782 An open label multi-center, phase 3 study with 2009-2011 corresponding blinded image reading to determine the efficacy and safety of a single intravenous injection of 0.1 mmol/kg body weight of gadobutrol 1.0 molar (Gadovist®)in patients with newly diagnosed breast cancer referred for contrast-enhanced breast MRI

. NCI/University of Colorado Data Analysis - MRI as an Adjunct to Mammography 2010

. VuComp I Data Acquisition Project 2008-2009

. VuComp II: M-Vu Clinical Study M-Vu Computer Aided Detection(CAD) for mammography, 2009-2010 designed to provide an unprecedented level of performance to help radiologists find breast cancer earlier

. SuperSonic Assessment of the Clinical Value of Supersonic Shear Wave 2003-2010 Elastography in the Ultrasonic Evaluation of Breast Lesions

. BIRADS Efficiacy of the ACR Breast Ultrasound BIRADS (Breast 2009-2014 Imaging Reporting and Data System)

Honors and Awards . Patient-centric Imaging Award, Health Imaging 2013 . Champions in HealthCare Award Finalist, Denver Business Journal 2010 . Internal Medicine Humanitarian Award, 1998-1999 Cook County Hospital, Department of Medicine . Intern Humanitarian Award, 1997-1998 Cook County Hospital, Department of Medicine

Report of Scholarship Peer-Reviewed Publications 1. Friedewald, S.M., Rafferty, E.A., Rose, S.L., Durand, M.A., Plecha, D.M., Greenberg, J.S., Hayes, M.K., Copit, D.S., Carlson, K.L., Cink, T.M., Barke, L.D., Greer, L.N., Miller, D.P., Conant, E.F. Breast Cancer Screening Using Tomosynthesis in Combination with Digital Mammography. JAMA, Jun 2014; 311(24): 2499-2507. Lora D. Barke, D.O. - Page | 3

2. Yi-Feng Lei, R., Leonard, C.E., Howell, K.T., Henkenberns, P.L., Johnson, T.K., Hobart, T.L., Kercher, J.M., Widner, J.L., Kaske, T., Barke, L.D., Carter, D.L. External Beam Accelerated Partial Breast Irradiation Yields Favorable Outcomes in Patients with Prior Breast Augmentation. Frontiers in Oncology, Jun 2014; 4(154): 1-11. 3. Leonard, C.E., Johnson T., Tallhamer, M., Howell, K., Kercher, J., Kaske, T., Barke, L.D., Sedlacek, S., Hobart, T., Carter, D.L. Accelerated Partial Breast Intesity-Modulated Radiotherapy in Women Who Have Prior Breast Augmentation. Clinical Breast Cancer, 2011; 11(3): 184-190. 4. Brinton, J.T., Barke, L.D., Freivogel, M.E., Jackson, S., O’Donnell, C.I., Glueck, D.H. Breast Cancer Risk Assessment in 64,659 Women at a Single High-Volume Mammography Clinic. Academic Radiology (in print) 2011. 5. Freivogel, M.E., Heydlauff, S., Barke, L.D. Identification of Candidates for Breast MRI Screening: Is the Gail Model Adequate? American Journal of Clinical Oncology, Oct 2010; 33(5): 530. 6. Barke, L.D., Stavros, A.T. Indications for Breast Ultrasound: Always Evolving. Ultrasound: Practical Sonography for the Radiologist. ARRS Categorical Course Syllabus Pages 75-84. 2009. 7. Hwang, H., Barke, L.D., Mendelson, E.B., Susnik, B. Atypical Lobular Hyperplasia and Classic Lobular Carcinoma In Situ in Core Biopsy Specimens: Routine Excision is Not Necessary. Modern Pathology 1-9. 2008. 8. Berns, E.A., Hendrick, R.E., Solari, M., Barke, L.D., Reddy, D., Wolfman, J., Segal, L., DeLeon, P., Benjamin, S., Willis, L. Digital and Screen-film Mammography: Comparison of Image Acquisition and Interpretation Times. AJR, Jul 2006; 187: 38-41. 9. Manders, J.B., Barke, L.D., Wahl, A.., Wolfman, J.W., Small, W., Keeney, K.M., Gradishar, W.J., Diaz, L.K. A Case Study from the Lynn Sage Comprehensive Cancer Center. Primary Sarcoma of the Breast: A Diagnostic Dilemma. Breast Cancer Online 2005:8:6. 10. Perlmutter, S.I., Iwamoto, Y., Barke, L.D., Baker, J.F., Peterson, B.W. Relation between Axon Morphology in C1 Spinal Cord and Spatial Properties of Medial Vestibulospinal Tract Neurons in the Cat. The American Physiological Society 1998: 285-303.

Committee Publications 1. Nass, S.J., Patlak, M., (2015) Rapporteurs; National Cancer Policy Forum; Board on Health Care Services; Institute of Medicine; The National Academies of Sciences, Engineering, and Medicine. Assessing and Improving the Interpretation of Breast Images, Workshop Summary 2015. Washington, DC. The National Academies Press. Available online at: http://www.nap.edu/read/21805/chapter/1 2. Seedah, B., Moy, L., Newell, M.S., Mahoney, M.C., Bailey, L., Barke, L.D., Carkaci, S., D’Orsi, C., Goyal, S., Haffty, B.G., Harvey, J.A., Hayes, M.K., Jokich, P.M., Lee, S., Mainiero, M.B., Mankoff, D.A., Patel, S.B., Yepes, M.M. ACR Appropriateness Criteria® Stage I Breast Cancer: Initial Workup and Surveillance for Local Recurrence and Distant Metastases in Asymptomatic Women, Journal of the American College of Radiology, Dec 2014; 11(12 Pt A): 1160-8. 3. Harvey, J.A., Mahoney, M.C., Newell, M.S., Bailey, L., Barke, L.D., D’Orsi, C., Hayes, M.K., Jokich, P.M., Lee, S., Lehman, C.D., Mainiero, M.B., Mankoff, D.A., Patel, S.B., Reynolds, H.E., Sutherland, M.L., Haffty, B.G. ACR Appropriateness Criteria® Palpable Breast Masses, Journal of the American College of Radiology, Oct 2013; 10(10): 742-749. 4. Mainiero, M.B., Lourenco, A., Mahoney, M.C., Newell, M.S., Bailey, L., Barke, L.D., D'Orsi, C., Harvey, J.A., Hayes, M.K., Huynh, P.T., Jokich, P.M., Lee, Su-Ju , Lehman, C.D., Mankoff, D.A., Nepute, J.A., Patel, S.B., Reynolds, H.E., Sutherland, M.L., Haffty, B.G. ACR Appropriateness Criteria® Breast Cancer Screening. Journal of the American College of Radiology, Jan 2013; 10(1): 11-14. Lora D. Barke, D.O. - Page | 4

5. Huynh, S.V., Lemeshko, M.C., Mahoney, M.S., Newell, L.B., Barke, L.D., D'Orsi, C., Harvey, J.A., Hayes, M.K., Jokich, P.M., Lee, Su-Ju, Lehman, C.D., Mainiero, M.B., Mankoff, D.A., Patel, S.B., Reynolds, H.E., Sutherland, M. L., Haffty, B.G. ACR Appropriateness Criteria® Stage I Breast Carcinoma. Journal of the American College of Radiology, July 2012; 9(7): 463-467.

Non-Peer-Reviewed Publications 1. Freivogel, M., Anguiano, A., Barke, L.D. A Complete Approach to Breast Cancer Screening. eRadimaging.com, March 2014. Available at: http://eradimaging.com/site/article.cfm?ID=811&mode=ce#.Uym2nfldXlY 2. Simmons, M. A., Goldsboro, J., Barke, L.D. Ergonomics in Mammography. eRadimaging.com, Dec 2013. Available at: http://eradimaging.com/site/article.cfm?ID=808&mode=ce 3. Simmons, M. A., Chavez, J., Barke, L.D. Patient Positioning and Mammography. eRadimaging.com, Sept 2012. Available at: http://www.eradimaging.com/site/article.cfm?ID=787 4. Barke, L.D., Paquelet J.R., Hendrick R.E. A Response to the U.S. Preventive Services Task Force Recommendations on Screening Mammography. The Advocate. Arapahoe-Douglas-Elbert Medical Society Newsletter. 5(1): 1-2, 6. Jan/Feb 2010. 5. Barke, L.D. Screening for Breast Cancer: A New Approach. eRadimaging.com March 2009. Available at: http://www.eradimaging.com/site/article.cfm?ID=637.

Abstracts, Poster Presentations and Exhibits at Professional Meetings 1. Lei, R.Y., Leonard, C.E., Howell, K.T., Henkenberns, P.L., Johnson, T.K., Hobart, T.L., Kercher, J.M., Widner, J.L., Kaske, T., Barke, L.D., Carter, D.L. External Beam Accelerated Partial Breast Irradiation (APBI) in Patients with Prior Breast Augmentation. International Journal of Radiation Oncology, Biology, Physics, 2013. 2. Lei, R.Y., Leonard, C.E., Howell, K.T., LaPorte, R.M., Henkenberns, P.L., Fryman, S.P., Hidgon, R.D., Widner, J.L., Barke, L.D., Carter, D.L. Disease Control Efficacy of Ductal Carcinoma In Situ (DCIS) Treated with Accelerated Partial Breast Irradiation (APBI). International Journal of Radiation Oncology, Biology, Physics 87(suppl):S196, 2013. 3. Lei, R.Y., Leonard, C.E., Howell, K.T., LaPorte, R.M., Henkenberns, P.L., Fryman, S.P., Higdon, R.D., Widner, J.L., Barke, L.D., Carter, D.L. Disease Control Efficacy of Ductal Carcinoma In Situ (DCIS) Treated With Accelerated Partial Breast Irradiation (APBI). American Society for Radiation Oncology (ASTRO). September 2013. Atlanta, GA. 4. Brinton, J.T., Barke, L.D., Freivogel, M., Jackson, S., O’Donnell, C.I., Glueck, D.H. Breast Cancer Risk Assessment in 64,659 Women at a Single High-Volume Mammography Clinic. September 2012. Denver, CO. 5. Cosgrove, D.O., Schafer, F., Svensson, W., Ohlinger, R., Mendelson, E, Locatelli, M., Tourasse, C., Cavanaugh, B.C., Juhan, V., Stavros, A.T., Barke, L.D., Tardivon, A., Hooley, R., Henry, J., Cohen-Bacrie, C., Dore, C., Gay, Joel. Adjunctive value of “shear wave” elastography (SWE) to the BI-RADS scoring system in the characterization of breast lesions: a prospective study on 1562 breast masses. The Italian Congress of Radiology. June 2012. Torino, Italy. 6. Brinton, J.T., Freivogel, M., Barke, L.D., Jackson, S., O’Donnell, C.I., Glueck, D.H. Improving Compliance with American Cancer Society Recommendations for Breast Cancer Screening in Women at Elevated Lifetime Risk. Presentation. New Investigators Workshop. American Society of Preventive Oncology. March 2012. Washington, D.C. Lora D. Barke, D.O. - Page | 5

7. Brinton, J.T., Freivogel, M., Barke, L.D., Jackson, S., O’Donnell, C.I., Glueck, D.H. Breast Cancer Risk Assessment in 64,659 Women at a Single High-Volume Mammography Clinic. Poster presentation. The Colorado Cancer Center Retreat. September 8, 2011, Colorado. 8. Brinton, J.T., Freivogel, M., Barke, L.D., Jackson, S., O’Donnell, C.I., Glueck, D.H. Adjunct Breast MRI screening in women with an increased risk for breast cancer: Only one in six women comply with American Cancer Society Guidelines when recommendations are made. Poster presentation. The 16th Annual Multidisciplinary Symposium on Breast Disease. Feb 2011, Amelia Island, Florida. 9. Brinton, J.T., Freivogel, M., Barke, L.D., Jackson, S., O’Donnell, C. I., Glueck, D. H. Women are rarely screened in accordance with American Cancer Society guidelines: Only one in sixteen women at high risk for breast cancer get an MRI as an adjunct to mammography. Podium presentation. ISP: Health Services, Policy and Research (Evidence based imaging and guidelines). Radiological Society of North America, 96th Scientific Assembly and Annual Meeting. Nov/Dec 2010, Chicago, IL. 10. Cosgrove, D.O., MBBch, MSc, London, GBR; Cohen Bacrie, C., MD, PhD; Dore, C.; Cavanaugh, B.C., MD; Balu-Maestro, C., ARRT; Madjar, H., MD; et al. ShearWave™ Elastrography improves the specificity of the BI-RADS classification of breast masses by ultrasound: results on 1000 cases in the Breast Elastography (BE1) investigators multicenter study. RSNA Annual Meeting 2010, Chicago 11. Cosgrove, D.O, Dore, C., Tourasse, C., Ohlinger, C., Madjar, H., Hooley, R., Balu-Maestro, C., Mendelson, E., Svensson, W., Tardivon,A., Cossi, A., Barke, L.D., Larsen, L. Preliminary assessment of ShearWave™ elastography features in predicting breast lesion malignancy. Royal College of Radiologists Breast Group Annual Scientific Meeting 2010, Brighton, U.K. 12. Freivogel M.E., Heydlauff S., Barke L.D. Identification of Candidates for Breast MRI Screening: Is the Gail Model Adequate? 20th Annual Interdisciplinary Care Conference of the NCBC 2010, Las Vegas. 13. Barke, L.D., Mendelson, E.B., Wolfman, J.W., and Kiel, K. Ultrasound-guided Percutaneous placement of the MammoSite RTS (Radiation Therapy System) for Partial Breast Irradiation (PBI): A Radiologic Procedure. RSNA Annual Meeting 2006, Chicago. 14. Barke, L.D., Johnson, A.J., Hwang, H, and Mendelson, E.B. Breast Imaging Case of the Day. RSNA Annual Meeting 2006, Chicago. 15. Gabriel H., Wiley E., Hendrick E., Barke L.D., et al. What is the true sensitivity and specificity of breast MRI: a mastectomy/MRI correlation study. ARRS 2006, Vancouver. 16. Berns, E.A., Hendrick, R.E., Barke, L.D. Comparison of Image Quality and Average Glandular Dose on Four FDA-approved Full-field Digital Mammography Systems. ARRS 2006 17. Jong, R.A., Umranikar, J.A., Hendrick, R.E., Berns, E.A., Yafee, M.J., et al. Performance of CAD on a FFDM System. RSNA Annual Meeting 2005, Chicago. 18. Yaffe, M.J., Jong, R.A., Wolfman, J.A., Hendrick, R.E., Causer, P.A., Curpen. B., et al. Performance of CAD for Pre-Screening with Digital Mammography. RSNA Annual Meeting 2005, Chicago. 19. Barke, L.D., Schreiber, E., Schiller, C., Mendelson, E.B. Breast Imaging Case of the Day. RSNA Annual Meeting 2005, Chicago. 20. Gabriel, H, Barke, L.D., Wolfman, J.W., Hendrick, R.E. Do automated methods of contrast kinetic analysis (CAD) improve inter-observer variability in breast MRI contrast kinetic analysis: A comparison study between automated and manual ROI determination. RSNA Annual Meeting 2005, Chicago. 21. Keen, J.D., Barke, L.D., Keen, J.E. Cost-effectiveness of Baseline Screening Mammography in Women Under 50. RSNA Annual Meeting 2005, Chicago. 22. Barke L.D., Tsai J.N., Mendelson E.B., Benjamin, S.D., Wiley, E.L., Diaz, L.K. Stromal Fibrosis: A Mimic of Breast Cancer Using Sonography and Contrast-Enhanced MRI. ARRS Annual Meeting 2005, New Orleans. Lora D. Barke, D.O. - Page | 6

23. Hendrick, R.E., Berns, E., Barke, L.D., Reddy D.M., Solari-Font M., Gabriel, H. Errors and Artifacts in Contrast-enhanced Breast MRI. RSNA Annual Meeting 2004, Chicago. 24. Hendrick, R.E., Berns E., Wolfman, J.A., Barke, L.D., Reddy, D.M., Mendelson, E.B. Study Time and User Preference between Screen-film and Digital for Screening Mammography. RSNA Annual Meeting 2004, Chicago. 25. Barke, L.D., Hendrick, R.E., Rausch, D., Gabriel, H., Burnside, E.S., Wolfman, J.W., Moran, C., Mendelson, E.B. Assessment of Breast Lesions Enhancing on MRI Using the ACR MR BI-RADS Lexicon and Other Criteria. ARRS Annual Meeting 2004, Miami. 26. Hendrick, E., Barke, L.D., Gabriel, H., Wolfman, J.W., Mendelson, E.M. Retrospective radiology/pathology correlation of MR lesions. ARRS Annual Meeting 2004, Miami. 27. Gabriel, H., Miller, L., Roberson, S., Burnside, E.S., Barke, L.D., Wolfman, J.W., Hendrick, R.E. How Reliable Are Time Signal Intensity Curves in Breast MR Interpretation. RSNA Annual Meeting 2003, Chicago. 28. Harris, V.J., Vade, A., Bruno, R., Barke, L.D. Sonographic Imaging for Scrotal Pathology in Pediatrics. AIUM Annual Meeting 2003. 29. Harris, V.J., Vade, A., Bruno, R., Barke, L.D. Pancreatic Lesions in Children. AIUM Annual Meeting 2003. 30. Krantz, A., Couture, E., Barke, L.D., Vawter, A., Hryhorczuk, D. Systemic Illness from Subcutaneous Elemental Mercury Injection. North American Congress of Clinical Toxicology. 2001, 39:5. 31. Barke, L.D., Balenalli, S. Sick Sinus Syndrome in a Patient with a Large Neck Mass. American College of Physicians Case Competition. October 1998. 32. Wester, C.W., Ariga, D., Nathan, C., Rice, T., Ajudia, K., Ortiz, J., Barke, L.D., Townsend, D., Pulvirenti, J. Incidence of Streptococcus Pneumoniae (SP) Colonization in HIV+ and HIV- outpatients at Cook County Hospital. Infectious Diseases Society of America. Abs. 1998. 33. Perlmutter, S.I., Barke, L.D., Iwamoto, Y., Powell, K.D., Baker, J.F., Peterson, B.W. Relations Between the C1 Terminal Arbors and Spatial Properties of Medial Vestibulospinal Tract Neurons (MVSN’s). Society for Neuroscience Abs. 1991, 128.9.

Invited Lectures 1. “Guidelines for Breast Cancer Screening Update: Annual Screening Beginning at 40 Saves the Most Lives” for RMCC. Englewood, CO. Feb 24, 2016 2. “Cancer Screening Guidelines: Separating Fact from Fiction” for 5th Annual Sky Ridge Medical Center 2015 Primary Care Conference. Lone Tree, CO. Aug 22, 2015 3. “VAB Vacuum Advantage with Dr. Barke” Bard Biopsy National Summer Sales Meeting 2015, Las Vegas, NV. Jul 15, 2015. 4. “Breast Density Update” for COPIC. Longmont United Hospital, Longmont, CO. Aug 29, 2014. 5. “Breast Density Update” for COPIC. Presbyterian/St. Luke’s Medical Center, Denver, CO. Jun 20, 2014. 6. “Breast Density Update” for COPIC. Parkview Medical Center, Pueblo, CO. May 29, 2014. 7. “Breast Density Update” for COPIC. Swedish Medical Center, Englewood, CO. Apr 17, 2014. 8. “Clinical Value of VAB” Bard Biopsy National Sales Meeting 2014, Scottsdale, AZ. Jan 26, 2014. 9. “Breast Cancer Screening Guidelines: What’s changed? What remains the same?” Grand Rounds Sky Ridge Medical Center, Greenwood Village, CO. Oct 1, 2013. Lora D. Barke, D.O. - Page | 7

10. “Breast Care Screening and Diagnosis: Making Sense of Guidelines and Protecting our Liability” Grand Rounds Swedish Medical Center, Englewood, CO. Sept 20, 2013. 11. “Breast MR Cases: Challenging Diagnostic Cases” RSNA, Chicago, IL. Nov 28, 2012 12. “Breast MR” Grand Rounds Regional West Medical Center, NE. Oct 29, 2012 13. “Women’s Health Symposium” Sky Ridge Medical Center, Greenwood Village, CO. Oct 20, 2012 14. “Breast Tomosynthesis” Grand Rounds Regional West Medical Center, NE. Apr 4, 2011 15. “Breast Density: The Two Edged Sword” Breast Ultrasound Conference, Las Vegas. Sept 2010 16. “Making Sense of the Breast Cancer Screening Guidelines” 2010 Summer CME Conference, Colorado Society of Osteopathic Medicine Breckenridge, CO. Aug 12, 2010. 17. “Digital Mammography and Breast MRI” Grand Rounds Regional West Medical Center, NE. Apr 6, 2010 18. “Breast Cancer: What you need to know” Surviving Cancer Lecture Series: Learn What You Can Do to Prevent, Identify, and Treat Cancer. The Given Institute Aspen, CO. Mar 10, 2010. 19. “Breast Imaging for Women: Beginning to End” Innovations in Women’s Cancer, Denver, CO. Nov 7, 2009. 20. “New Frontiers in Breast Imaging” Colorado Mammography Society. Colorado Springs, CO. Sept 12, 2009. 21. “Breast Cancer Screening and Managing High Risk Patients” for COPIC. Valley View Hospital Glenwood Springs, CO. May 21, 2009. 22. “Breast Cancer Screening and Managing High Risk Patients” for COPIC. Aspen Valley Hospital , Aspen, CO. May 21, 2009. 23. “Indications for Breast Ultrasound: Always Evolving” ARRS Annual Meeting. Categorical Course in Ultrasound: Practical Sonography for the Radiologist. Apr 26-May 1, 2009. 24. “Breast Cancer Screening and Managing High Risk Patients” for COPIC. Longmont United Hospital, Longmont, CO. Apr 17, 2009. 25. “Breast Cancer Screening and Managing High Risk Patients” for COPIC. Medical Center of Aurora, North Campus, Aurora, CO. Feb 13, 2009. 26. “Indications for Breast Ultrasound” Radiology Imaging Associates Tech Workshop, CO. Feb 8, 2009. 27. “Breast Imaging: New Technology” Radiology Imaging Associates Tech Workshop, CO. Feb 8, 2009. 28. “CAD for Mammography: What is the True Value?” RSNA Chicago. Dec 2008. 29. “Screening for Breast Cancer and Managing High Risk Patients” Colorado Mammography Society Niwot, CO. Sept 20, 2008. 30. “Managing Breast Cancer Patients” for COPIC Montrose Memorial Hospital Montrose, CO. Aug 9, 2008. 31. “Managing Breast Cancer Patients” for COPIC Delta County Memorial Hospital Delta, CO. Aug 8, 2008. 32. “Screening for Breast Cancer: A New Approach” - 33rd National Primary Care Nurse Practitioners Symposium, Keystone, CO. Jul 2008. 33. “Early Detection: The Key to Breast Cancer Treatment and Osteoporosis Prevention” Sky Ridge Hospital Health Fair, CO. May 17, 2008. 34. “CAD for Mammography: What is the True Value?” RSNA Chicago. Dec 2007, Dec 2008. 35. “What Digital Mammography Means to the Breast Cancer Patient” Porter Hospital, Denver, CO. Oct 2007. Lora D. Barke, D.O. - Page | 8

36. “Tips, Trick and Troubleshooting” Redefining the Spectrum of Breast Care, Boston. Sept 2007. 37. “Role of Breast MRI” Redefining the Spectrum of Breast Care, Boston. Sept 2007. 38. “Interventional Procedures Hands-on” Redefining the Spectrum of Breast Care, Boston. Sept 2007. 39. “Update on Breast Imaging I (Mammography, Ultrasound)” Novel Frontiers on Breast Cancer Research, Chicago. May 2006. 40. “Ultrasound Guided Interventional Procedures” - The Chicago International Breast Course. Sept 2005. 41. Mammography Section Case Review - Chicago Radiologic Society. Apr 2004.

Teaching/Course Leadership: 1. “Mastering Breast Biopsy – Radiology Training Course” Bard Biopsy Systems & Invision Sally Jobe. Nov 12-13, 2015. 2. “Mastering Breast Biopsy – Radiology Training Course” Bard Biopsy Systems & Invision Sally Jobe. Sept 17-18, 2015. 3. “Screening for Breast Cancer: What should a Breast Sonographer Know?” Invision Sally Jobe & Centrum Surgical Center Ultrasound Breast Book Club Program, Apr 15, 2015. 4. “Mastering Breast Biopsy – Radiology Training Course” Bard Biopsy Systems & Invision Sally Jobe. Apr 9-10, 2015. 5. “Mastering Breast Biopsy – Radiology Training Course” Bard Biopsy Systems & Invision Sally Jobe. Feb 5-6, 2015. 6. “Mastering Breast Biopsy – Radiology Training Course” Bard Biopsy Systems & Invision Sally Jobe. Oct 23-24, 2014. 7. “Mastering Breast Biopsy – Radiology Training Course” Bard Biopsy Systems & Invision Sally Jobe. Apr 10-11, 2014. 8. “Live Case Observations” Bard Biopsy Systems & Invision Sally Jobe. Live clinical demos of US biopsies for clinical engineers from China. Apr 4, 2014. 9. “Mastering Breast Biopsy – Radiology Training Course” Bard Biopsy Systems & Invision Sally Jobe. Feb 13-14 2014. 10. “Mastering Breast Biopsy – Radiology Training Course” Bard Biopsy Systems & Invision Sally Jobe. Aug 22-23 2013. 11. “Breast Care Screening and Diagnosis: Making Sense of Guidelines and Protecting our Liability” Invision Sally Jobe & Swedish Medical Center Multidisciplinary Educational Program. Aug 13 & 28th 2013. 12. “Breast Density Update” Invision Sally Jobe Technologist Training Course, May 30, 2013. 13. Course Director, Innovations in Women’s Cancer, Denver, CO. Nov 7, 2009. 14. Northwestern University, Feinberg School of Medicine - Problem Based Learning 201, Fall 2005

Lora D. Barke, D.O. - Page | 9

Media 1. “Federal task force: change breast cancer screening age from 40 to 50” The Aspen Times Jan 2016. Available at: http://www.aspentimes.com/news/20116446-113/federal-task-force-change-breast- cancer-screening-age 2. “New Mammography Guidelines Worry Breast Cancer Experts” CBS 4 Denver broadcast Jan 13, 2016. Available at: http://denver.cbslocal.com/2016/01/13/new-mammography-guidelines-worry-breast- cancer-experts/ 3. “Some Doctors, Breast Cancer Survivors Skeptical of New Screening Guidelines” Fox 31 Denver broadcast Oct 22, 2015. Available at: http://kdvr.com/2015/10/22/some-doctors-breast-cancer- survivors-skeptical-of-new-screening-guidelines/ 4. “9News Doctors Line 9” 9News broadcast Sept 15, 2015. 5. “Invision Sally Jobe” HerLife Magazine Spotlight: pp. 12-13. Oct 2014. 6. “All in Pink” The Denver Post. Oct 2014. Available at: http://extras.denverpost.com/pink/stories.html#panel7http://extras.denverpost.com/pink/stories.ht ml#panel7 7. “The Debate Around Getting a Mammogram” 9News broadcast Sept 18, 2014. Available at: http://www.9news.com/story/news/health/2014/09/18/mammogram-debate/15843971/ 8. “9News Doctors Line 9” 9News broadcast Sept 18, 2014. 9. “Ultrasound is option when mammography doesn’t work for breast cancer screening” Fox 31 Denver broadcast Aug 11, 2014. Available at:http://kdvr.com/2014/08/11/ultrasound-is-option-when- mammaography-doesnt-work-for-breast-cancer-screening/ 10. “Breast Health Update” GrassRoots Television, Inc. - Medicine in the Mountains broadcast Jul 23, 2014. 11. “Study: 3D mammography more effective than traditional mammograms” Fox 31 Denver broadcast Jun 25, 2014. Available at: http://kdvr.com/2014/06/24/study-3-d-mammography-more-effective- than-traditional-mammograms/ 12. “Invision Sally Jobe” HerLife Magazine Spotlight: pp. 12-13. Oct 2013. 13. “2013 Patient-centric Imaging Awards” Health Imaging Magazine Spotlight: September/October 2013 Edition. Available at: http://www.healthimaging.com/topics/practice-management/2013-patient- centric-imaging-awards 14. “Lifting the Fog on Breast Cancer Screening and Risks” Colorado Health & Wellness, Boomer Edition, 9th Annual, 2013. 15. “Breast Density Update” RIA/ISJ Webex - Nov 14, 2012. Available at: https://riaco.webex.com/riaco/lsr.php?AT=pb&SP=MC&rID=63323002&rKey=b7eaf7183961dabf 16. “Breast-cancer study gives doctors, patients hope” 9News broadcast Sept 25, 2012. Available at: http://www.9news.com/news/health/article/291121/180/Breast-cancer-study-gives-doctors-patients- hope 17. “Early Detection in Breast Cancer” GrassRoots Television, Inc. - Medicine in the Mountains broadcast Jun 5, 2012. Available at: http://www.grassrootstv.org/Show.aspx?ShowID=10869 18. “A Better Way to Perform a Mammogram” 9News broadcast May 8, 2010. Available at: http://www.9news.com/rss/story.aspx?storyid=138431 Acknowledgements Lora D. Barke, D.O. - Page | 10

WA Berg et al. Shearwave Elastography Improves the Specificity of Breast Ultrasound: The BE1 Multinational Study of 939 Masses, manuscript #11-0640. Bethany L. Niell, M.D., Ph.D May 25, 2016

Bethany Lynn Niell, M.D., Ph.D. (nee Fisher) May 25, 2016

Current Position: Associate Member Department of Diagnostic Imaging Moffitt Cancer Center 12902 Magnolia Drive Tampa, FL 33612 (813)-745-4183 phone# (813)-745-5762 fax# [email protected]

Current Academic Appointments: Associate Professor Department of Oncologic Sciences, MCC 44 College of Medicine University of South Florida 12901 Bruce B. Downs Blvd. Tampa, FL 33612 Department of Radiology Joint Appointment with USF

Education: 1995-1998 B.S. (Summa Cum Laude) Chemistry University of Illinois at Urbana, Champaign, IL

1998-2005 M.D. Medicine University of Michigan School of Medicine, Ann Arbor, MI

1998-2005 Ph.D. Epidemiology University of Michigan Rackham School (Stephen Gruber, M.D., Ph.D.) of Graduate Studies of Graduate Studies, Ann Arbor, MI

Postgraduate Training and Fellowship Appointments: 2005-2006 Intern, Transitional Year St. Joseph Mercy Hospital, Ypsilanti, Michigan, IL

2006-2010 Resident - Diagnostic Radiology Massachusetts General Hospital, Boston, MA

2008-2009 Chief Resident Diagnostic Radiology Massachusetts General Hospital, Boston, MA

Academic Appointments and Employment: 2010-2014 Instructor (Faculty) Radiology Harvard Medical School, Boston, MA

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Bethany L. Niell, M.D., Ph.D May 25, 2016

2015 Assistant Professor Radiology Harvard Medical School, Boston, MA

Employment: 2015-present Associate Member H. Lee Moffitt Cancer Center and Research Institute Department of Diagnostic Imaging

Academic Appointments: 2015-present Associate Professor Department of Oncologic Sciences College of Medicine, University of South Florida

Licenses: 2005-2006 Michigan M.D. L-4301085655 Inactive 2006-2007 Massachusetts M.D. L-227659 Inactive 2007-present Massachusetts M.D. 231163 Active 2015-present Florida ME124780 Active

Board Certifications: 2010-present American Board of Radiology

Language Spoken: English

Teaching Experience

University Courses: 1996-1998 Course Instructor, University of Illinois at Urbana-Champaign, Chemistry 101, Undergraduate students 1997-1998 Course Instructor, University of Illinois at Urbana-Champaign, Introduction to Human Genetics, Undergraduate students 2003 Course Instructor, University of Michigan School of Medicine, Basics of Epidemiology, Medical Students 2013-2015 Course Instructor, Harvard Medical School, Core Clerkship in Diagnostic Radiology RD500M.3 Division of Breast Imaging representative, Medical Students 2015-present Clinical Instructor: Breast Imaging MDE8772, College of Medicine, University of South Florida, Tampa, FL

Other Courses and National Symposia: 6/22/2011 Course Instructor, Massachusetts General Hospital, Breast Imaging Mini- course “BIRADS Lexicon”, Diagnostic radiology residents, One hour 6/24/2011 Course Instructor, Massachusetts General Hospital, Breast Imaging Mini- course “Breast MRI”, Diagnostic radiology residents, One hour 2011-2015 Course Instructor, Massachusetts General Hospital, Breast Imaging case conference series, Diagnostic radiology residents, One hour session, once per year

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Bethany L. Niell, M.D., Ph.D May 25, 2016

7/8/2011-2015 Course Director, Massachusetts General Hospital, “Contrast Reaction Management in MGH Imaging”, Diagnostic radiology clinical fellows, One hour, once per year 2011-2014 Course Instructor, Massachusetts General Hospital, Senior Resident Oral Boards Review, Diagnostic radiology residents, One and two hour sessions, once per year 4/12/2012 Course Instructor, Massachusetts General Hospital, Magnetic Resonance Imaging Technologist In-Service “Breast MRI”, MRI Technologists, Two, 1- hour sessions 4/25/12 & Course Instructor, University of Massachusetts Department 5/14/13 of Radiology, Senior Resident Oral Boards Review, Diagnostic radiology residents, Two hour session, once per year 5/11/2012 Course Instructor, Massachusetts General Hospital, Breast Imaging Mini- course “Breast MRI”, Diagnostic radiology residents, One hour session 2012, 2014 Faculty Moderator, Massachusetts General Hospital, Radiology-Pathology Correlation Series, Diagnostic radiology residents, One hour session 2012-2015 Course Director and small group workshop faculty, Massachusetts General Hospital, Medical simulation exercises for contrast and emergency management, Continuing education credit programs for physicians, nurses, and technologists 2012-2015 Course Instructor, Massachusetts General Hospital, Breast Imaging Fellowship Education Lectures, clinical fellows, One hour session, two to four lectures per year 2012-2015 Course Instructor, Massachusetts General Hospital, Breast Imaging Journal Club, Diagnostic radiology residents and clinical fellows, One hour session, two sessions per year 5/23/2014 Course Instructor, Massachusetts General Hospital, Breast Imaging Mini- course “Breast MRI”, Diagnostic radiology residents, One hour session 4/7/2015 Course Instructor, Brigham and Women’s Hospital/Massachusetts General Hospital Radiology Review Course, “Introduction to Breast MRI” 12/3/2015 Course Instructor, Radiological Society of North America annual meeting, “MR-Imaging Guided Breast Biopsy (Hands On)” 5/19/2016 Course instructor, University of South Florida, Department of Radiology, Senior Resident Oral Boards Review, Diagnostic radiology residents, Two hour session, once per year

Teaching and Training Experience: Graduate training: 2014-2015 Committee Member, Ph.D. Graduate Student Supervisory Committee for Alexandra Penzias, R.N., Regis College School of Nursing 2014-2015 Clinical Mentor, Ph.D. Graduate Student Supervisory Committee for Craig White, Decision Sciences concentration of the Ph.D. Program in Health Policy at Harvard University

Residents/Clinical Fellows/Post-Doctoral trainees: 2010-2011 Chris Johansen, MD Staff Radiologist, Kingman Regional Medical Center Description: I supervised a fellow physician research project regarding patient outcomes in aborted MR guided breast biopsies. Our abstract was presented as a poster presentation at the 2012 Radiological Society of North America Annual

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Bethany L. Niell, M.D., Ph.D May 25, 2016

Meeting. The manuscript was published in the American Journal of Roentgenology in January 2014. 2011-2012 Wade Hedegard, MD Staff Radiologist, Elizabeth Wende Breast Care, LLC Description: I supervised a fellow physician research project regarding the imaging appearance and complications of autogenous breast reconstruction with a deep inferior epigastric perforator flap following mastectomy. The manuscript was published in the American Journal of Roentgenology in 2013. 2011-2012 Vartan Vartanians, MD Radiology resident, Lahey Clinic, Burlington, MA Description: I supervised a Massachusetts General Hospital research fellow on a study evaluating the efficacy of an online module to educate radiologists on contrast and emergency management within our Department. The abstract was presented orally at the 2012 Radiological Society of North America Annual Meeting. The manuscript was published in the Journal of the American College of Radiology in February 2014. I invited the resident to serve as the co-director faculty for an instructional course at the American Roentgen Ray Society 2015 Annual Meeting. 2012-2014 Taj Kattapuram, MD Radiology resident, Massachusetts General Hospital Description: I supervised a radiology resident on a project evaluating the incremental efficacy of medical simulation, in addition to didactic instruction, for the education of radiologists, technologists, and nurses in contrast and emergency management within our Department. The resident presented orally at the 2014 Radiological Society of North America Annual Meeting. 2013-present Nita Amornsiripanitch, MD Radiology resident, Massachusetts General Hospital Description: I am supervising a radiology resident on a project to develop, implement, and evaluate the effectiveness of an embedded decision support tool for further evaluation of liver lesions detected on breast MRI. I am also supervising this resident on a project which investigates patients’ perceptions and preferences regarding the communication of their estimated lifetime breast cancer risk. 2014 Debbie Bennett, MD Attending Radiologist, Saint Louis University Description: I supervised a fellow physician on data extraction for a project which evaluated the frequency, clinical relevance, and costs of incidental extra-mammary findings detected on breast MRI.

2015-present: Breast Imaging Fellows – Two 1-year fellowships each year at Moffitt Cancer Center

2015-present: Breast Surgery Fellows – One fellow for one month per year at Moffitt Cancer Center

Faculty Mentoring: 2014-2015 Phoebe Freer, MD Instructor (Faculty), Department of Radiology, Massachusetts General Hospital 2014-2015 Pragya Dang, MD Instructor (Faculty), Department of Radiology, Massachusetts General Hospital

Honors and Awards 1998 Bronze Tablet Award University of Illinois at Urbana Champaign, IL 2003 Student Award for research in molecular American Association for Cancer and genetic epidemiology of cancer Research and AstraZeneca 2004 Alpha Omega Alpha University of Michigan School of Medicine 2006 Intern of the Year St. Joseph Mercy Hospital

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Bethany L. Niell, M.D., Ph.D May 25, 2016

Department of Internal Medicine 2012 Partners in Excellence Team Award Partners Healthcare 2012 Certificate of Merit Radiological Society of North Education Exhibit “Artifacts on America Scientific Assembly and Tomosynthesis: An Illustrative Review Annual Meeting 2012 2014 Partners in Excellence Team Award Partners Healthcare Contrast and Emergency Management Simulation 2015 Academic Faculty Development Program Association of University Radiologists Annual Meeting

Research Support Pending:

External Grants:

DOD # 12159001 PI: Bethany Niell, MD PhD Dates: Title: Breast Cancer Risk and Quantitative measures of Fibroglandular Tissue and Background Parenchymal Enhancement on Breast Magnetic Resonance Imaging (MRI) % Effort: %

Completed:

Internal Grants: Name of PI: James Gordon, MD Dates: 2013-present Funding Source: Partners HealthCare Title: Departmental Simulation Officer Educational Project % Effort: 10% Role in the Study: As the departmental simulation officer (DSO) for the Massachusetts General Hospital Department of Radiology, I oversee and coordinate the clinical simulation activities within my department and work in collaboration with other DSOs/departments to optimize simulation as a core element of hospital quality and safety. Total Amount of Award: $20,000 per year

Training Grants: Account #: T32 GM07863 Dates: 1998-2005 Funding Source: National Institute of General Medical Science Title: University of Michigan Medical Scientist Training Program

Account #: T32 HG00040 Dates: 2001-2003 Funding Source: National Human Genome Research Institute Title: University of Michigan Training Program in Genomic Science

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Bethany L. Niell, M.D., Ph.D May 25, 2016

Dissertation

Niell BL (2003) Colorectal Cancer Epidemiology: Genes, Environment, and History. Doctoral dissertation, Department of Epidemiology, School of Public Health, University of Michigan Rackham School of Graduate Studies

Service

Massachusetts General Hospital Administrative Appointments: 2010-2015 Director of Breast MRI Department of Radiology 2012-2015 Course Co-Director Department of Radiology Continuing Medical Education Program: Simulation in MGH Imaging: Contrast and Emergency Management with Team Training (Harvard Medical School Regularly Scheduled Series #3028) 2013-2015 Departmental Simulation Officer - Radiology

Committees: 2008-2009 Emergency Radiology Division Committee, Department of Radiology Member, one hour, once per month 2008-2009 Education Committee, Department of Radiology Member, one hour, once per month 2009-2015 Contrast and Emergency Management Task Force, Department of Radiology Member, one hour, once per month 2011-2015 Breast Imaging Quality Assurance Liaison, Department of Radiology Member, three hours, twice per month 2012-2015 New and Junior Faculty Development Committee, Department of Radiology Member, one hour, once per month 2013-2014 Radiology Associates Executive Committee Member, one hour, twice per year 2014-2015 Team Training Committee, Department of Radiology Member, one hour, once per month 2014-2015 Clinical Decision Support Algorithm Development, Department of Radiology Member, one hour, once per month

H. Lee Moffitt Cancer Center and Research Institute Committees: 2015-present Member, Peer Review Committee, Department of Diagnostic Imaging

Service to Professional Organizations

Professional Publications: 2012-present Reviewer, Breast Cancer Research and Treatment 2014-present Reviewer, The Breast Journal 2015-present Reviewer, Cancer Control Journal

Professional Committees: 2012-present Society of Breast Imaging Membership Committee

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Bethany L. Niell, M.D., Ph.D May 25, 2016

Member, One hour, once per month 2014-2015 Alliance of Clinician Educators Education Committee Member, One hour, every other month 2015-present American College of Radiology and Society of Breast Imaging Breast Cancer Screening Leadership Group Member 2015-present Government Relations Committee, American College of Radiology Commission on Breast Imaging Member

Community: 2001-2002 Assistant Leader - Girl Scouts of America Troop 245 Oct. 21, 2015 Interviewed by Lindsey Mastis “Cancer society’s mammogram advice: Start later and get fewer” WFLA, Channel 8 News, Tampa, FL Oct. 21, 2015 Telephone interview with Robin Williams Adams, The Ledger. Local experts concerned about American Cancer Society’s recommendation to delay mammography screening. Lakeland, FL Oct. 23, 2015 Interviewed for Behind The Scenes at Moffitt. Discussed the new American Cancer Society guidelines on mammograms on Bay News 9, Tampa, FL Jan 13, 2016 Interviewed by Candace McCowan regarding the US Preventive Services Task Force’s updated guidelines for mammograms, WFLA Channel 8 News, Tampa, FL May 17, 2016 Invited speaker at Moffitt Merit Society, “Increasing Appropriate Utilization of Breast MRI in High Risk Women.”

Professional Association Memberships

2005-2010 New England Roentgen Ray Society 2005-present Radiological Society of North America (RSNA) 2005-present American Board of Radiology 2009-present American Medical Association 2009-present American Roentgen Ray Society 2010-present American College of Radiology (ACR) 2010-2015 Massachusetts Medical Society 2012-present Society of Breast Imaging 2013-2015 Society for Simulation in Healthcare 2014-present Association of University Radiologists 4/2/2014 Co-Moderator, “When Policy Outpaces Evidence: The Case of Breast Density Legislation”, Association of University Radiologists Annual Meeting, Baltimore, MD 4/14/2015 Moderator, “Innovating Teaching Strategies”, Association of University Radiologists Annual Meeting, New Orleans, LA 2014-present Member, Alliance of Clinician-Educators in Radiology (ACER) 2014-present Member, Radiology Alliance for Health Services Research

Peer-Reviewed Publications

1. Erson AE, Niell BL, DeMers SK, Rouillard J, Hanash SM, Petty EM. Overexpressed genes/ESTs and characterization of distinct amplicons on 17q23 in breast cancer cells. Neoplasia 3:521-526, 2001

2. Niell BL, Long JC, Rennert G, Gruber SB. Genetic anthropology of the colorectal cancer- susceptibility allele APC I1307K: evidence of genetic drift within the Ashkenazim. American Journal of Human Genetics 73:1250-1260, 2003

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Bethany L. Niell, M.D., Ph.D May 25, 2016

3. Niell BL, Rennert G, Bonner JD, Almog R, Tomsho JP, Gruber SB. BRCA1 and BRCA2 founder mutations and the risk of colorectal cancer. Journal of the National Cancer Institute 96:15-21, 2004

4. Greenwood CM, Sun S, Veenstra J, Hamel N, Niell B, Gruber S, Foulkes WD. How old is this mutation?- a study of three Ashkenazi Jewish founder mutations. BMC Genetics 11:39-46, 2010

5. Niell BL, Specht M, Gerade B, Rafferty EA. Is excisional biopsy required after a breast core biopsy yields lobular neoplasia? American Journal of Roentgenology 199(4): 929-935, 2012

6. Hedegard H*, Niell BL, Specht M, Winograd J, and Rafferty EA. Breast reconstruction with a deep inferior epigastric perforator (DIEP) flap: Imaging appearances of the normal flap and common complications. American Journal of Roentgenology 200(1): W75-84, 2013

7. Carter JB, Barnes JA, Niell BL, and Nardi V Case 24-2013: A 53-year-old woman with erythroderma, pruritis, and lymphadenopathy. The New England Journal of Medicine 369(9): 559- 569, 2013

8. Niell BL, Lee JM, Johansen C*, Halpern EF, Rafferty EA. Patient outcomes in cancelled magnetic resonance guided breast biopsies. American Journal of Roentgenology 202(1):223-228, 2014 *Clinical Fellow trainee

9. Niell BL, Vartanians VM*, Halpern E. Improving education for the management of contrast reactions: an online didactic model. Journal of the American College of Radiology 11(2):185-192, 2014 *Research Fellow trainee

10. Niell BL, Gavenonis SC, Motazedi T, Chubiz JC, Halpern EF, Rafferty EA, Lee JM. Auditing a breast MRI practice: performance measures for screening and diagnostic breast MRI. Journal of the American College of Radiology 11(9): 883-889, 2014

11. Freer P, Niell BL, and Rafferty EA. Pre-operative tomosynthesis-guided needle localization of mammographically and sonographically occult breast lesions. Radiology (2015) 275(2):377-383, 2015

12. Niell BL, Kattapuram T*, Halpern EF, Salazar GM, Penzias A, Bonk SS, Forde JC, Hayden E, Sande M, Minehart RD, and Gordon JA. Prospective analysis of an interprofessional team training program using high-fidelity simulation of contrast reactions. American Journal of Roentgenology *Resident physician trainee, 2015 Jun;204(6):W670-6.

13. Niell BL, Bennett D, Sharma A, and Gazelle GS. Extra-mammary findings on breast MRI examinations: frequency, clinical relevance, and patient outcomes. Radiology, 2015 Jul;276(1):56- 64.

Non-Peer Reviewed Publications

Case reports and Letters to the Editor

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Bethany L. Niell, M.D., Ph.D May 25, 2016

1. Niell BL and D’Alessandro HA. Left innominate vein occlusion mimicking inflammatory breast carcinoma. American College of Radiology Case in Point, 2010

2. Niell BL, Rennert G, Bonner JD, Gruber SB. Response: Re: BRCA1 and BRCA2 mutations and the risk of colorectal cancer. Journal of the National Cancer Institute 96:1185- 6, 2004

3. Niell BL, Specht M, and Rafferty EA. Reply: Re: Is excisional biopsy required after a breast core biopsy yields lobular neoplasia? American Journal of Roentgenology 200(5): W539, 2013

Patient Educational Material

Niell BL, Rafferty EA. Massachusetts General Hospital Breast Imaging Patient information regarding Magnetic Resonance Imaging (MRI) guided breast biopsy, 2010

Professional Educational Materials, in print or other media

2010 Massachusetts General Hospital Diagnostic Radiology Residency Training Curriculum in Breast Imaging 2010 Massachusetts General Hospital Department of Imaging Online Educational Module regarding the management of adverse events to intravenous contrast. 2014 Contributing author, Massachusetts General Hospital Department of Imaging Radiology Rounds A Newsletter for Referring Physicians “Breast Tomosynthesis” August 2014 issue 2014 “Working in Interdisciplinary teams”, American College of Radiology, web-based module . 2015 “Screening for Breast Cancer: Debunking Common Myths,” A community health education webinar.

Clinical Guidelines and Reports

2010 Massachusetts General Hospital Department of Radiology 2010 Treatment algorithms for the management of acute contrast reactions. I developed evidence based management algorithms and kits containing the necessary supplies to treat a reaction, in conjunction with the contrast and emergency management committee. 2013 Massachusetts General Hospital Department of Radiology 2013 Revised treatment algorithms for the management of acute contrast reactions. I revised evidence based management algorithms that were approved for use and distribution throughout the Department. 2014 Massachusetts General Hospital Department of Radiology Clinical Decision Support algorithm for the management of hepatic lesions incidentally detected on breast MRI. I mentored a resident during the development of the algorithm.

Abstracts, Poster Presentations and Educational Exhibits Presented at Professional Meetings (during the last 3 years, which have not already been published as full length manuscripts):

1. Freer P, Niell BL, and Rafferty EA. Artifacts on tomosynthesis: an illustrative review. Oral presentation, Radiological Society of North America 2012 Annual Meeting, Chicago, IL

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Bethany L. Niell, M.D., Ph.D May 25, 2016

2. Fishman M, Saksena M, Niell B, Brachtel EF, and Rafferty EA. The Many Faces of Breast Lymphoma: A Radiologic Pathologic Correlation. Electronic exhibit, American Roentgen Ray Society 2013 Annual Meeting, Washington D.C.

3. Niell BL, Bonk S, Forde J, Penzias A, and Salazar GM. Targeting educational deficits: Lessons learned from team performance during simulated contrast reactions. Oral presentation, Association of University Radiologists 2015 Annual Meeting, New Orleans, LA

4. Niell BL, Bonk S, Forde J, Penzias A, and Salazar GM. Multi-year experience from a department- wide interprofessional team training program of simulated adverse contrast reactions. Oral presentation, American Roentgen Ray Society 2015 Annual Meeting, Toronto, Ontario

Invited Seminars

3/2011 “Contrast and Emergency Management in MGH Imaging”, Quality Assurance Lecture series, Massachusetts General Hospital Department of Radiology 4/2011 “Excisional Biopsy Upgrade Rate of Lobular Neoplasia diagnosed on core breast biopsy”, Oral abstract presentation, American Roentgen Ray Society Annual Meeting, Crystal City, VA 1/9/2012 “Contrast and Emergency Management”, Massachusetts General Hospital Department of Radiation Oncology 4/2012 & “Breast MRI”, Brigham and Women’s Hospital/Massachusetts General 4/2013 Hospital Radiology Review Course 4/2012 “Management of the High Risk Lesion”, New Horizons in Breast Imaging Continuing Medical Education Course, New York, NY (Oakstone and World Class CME) 4/2012 “Breast MRI: Diagnostic Indications”, New Horizons in Breast Imaging Continuing Medical Education Course, New York, NY (Oakstone and World Class CME) 4/2012 “Clinical Case Conference” Panel discussant and lecturer, New Horizons in Breast Imaging Continuing Medical Education Course, New York, NY (Oakstone and World Class CME) 4/2012 “Breast MRI: Screening Indications”, New Horizons in Breast Imaging Continuing Medical Education Course, New York, NY (Oakstone and World Class CME) 11/2012 “Improving the management of contrast reactions: an online educational model”, Oral abstract presentation, Radiological Society of North America Annual Meeting, Chicago, IL 4/2013 & “Breast calcifications” Brigham and Women’s Hospital/Massachusetts General 4/7/2014 Hospital Radiology Review Course 6/13/2013 “Contrast and emergency management with an emphasis on team training”, Simulation spotlight quarterly series, Massachusetts General Hospital 6/16/2013 “Simulation in MGH Imaging”, Works in progress series, Partners Office of Graduate Medical Education, Massachusetts General Hospital 10/19/2013 “Contrast and Emergency Management Simulation”, Hampton Symposium Frontiers in Imaging Massachusetts General Hospital 10/31/13 “Simulation in Radiology”, Lunch and Learning series, MGH NorthShore Medical Center 11/2013 “Breast Imaging: Using the technology Wisely”, Advances in Cancer Management for the Surgeon Harvard Medical School Review Course 10/16/2014 “Monthly Radiology Safety Moment: Simulation in MGH Imaging: A brief update”, Department of Radiology faculty meeting, Massachusetts General Hospital

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Bethany L. Niell, M.D., Ph.D May 25, 2016

10/31/2014 “Simulation in the MGH Department of Radiology”, Simulation Advisory Board, Massachusetts General Hospital 12/17/2014 “Common Artifacts and Pitfalls on Breast MRI”, Beth Israel Deaconess Medical Center, Department of Radiology, Clinical MRI 2014: From Structure to Function 2/19/2015 “Simulation in Radiology”, Association of Vascular and Interventional Radiographers national meeting, Atlanta, GA 3/2/2015 “Contrast and Emergency Management Simulation in MGH Radiology”, Executive Committee on Teaching and Education (ECOTE), Partners HealthCare 3/20/2015 “Medical Simulation in Radiology: Who, How, and Why?”, Visiting Professor, Georgia Regents University-Medical College of Georgia Department of Radiology, lecture and small group workshop faculty 4/9/2015 “Contrast Crisis Simulation Workshop”, Brigham and Women’s Hospital/Massachusetts General Hospital Radiology Review Course 4/16/2015 “Targeting educational deficits: Lessons learned from team performance during simulated contrast reactions”, Oral abstract presentation, Association of University Radiologists 2015 Annual Meeting, New Orleans, LA 4/20/2015 “Multi-year experience from a department-wide interprofessional team training program of simulated adverse contrast reactions”, Oral abstract presentation, American Roentgen Ray Society 2015 Annual Meeting, Toronto, Ontario 4/22/2015 “Improving education: Management of contrast reactions” (Instructional Course #316), American Roentgen Ray Society 2015 Annual Meeting, Toronto, Ontario 5/21/2015 “Supplemental Screening for breast cancer”, Massachusetts General Hospital Department of Obstetrics and Gynecology Grand Rounds

Other Education:

October 15-20, 2012 Institute for Medical Simulation Comprehensive Instructor Workshop, Cambridge, MA

Other Research:

2011-2015 Co-Investigator Utility of MR-PET in breast imaging

2012-2015 Principal Investigator Incremental effectiveness of medical simulation 2015-present Co-Investigator over didactic instruction for improving contrast and emergency management in Radiology and Radiation Oncology

2014-2015 Principal Investigator Development and effectiveness of clinical decision support tool for liver lesions detected on breast MRI

2014-2015 Principal Investigator Perception of nursing presence in patients 2015-present Co-Investigator undergoing MRI-guided breast biopsy

2014-2015 Co-Investigator Utility of breast MRI for equivocal mammographic 2015 Principal Investigator and tomosynthesis findings

2014-2015 Co-Investigator Survey of patients’ preferences regarding educational materials on breast cancer screening and breast imaging

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Bethany L. Niell, M.D., Ph.D May 25, 2016

2014-2015 Principal Investigator Patients’ Perceptions and Preferences regarding 2015-present Co-Investigator communication of estimated breast cancer risk

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