CDC5L Antibody Cat. No.: 63-716

CDC5L Antibody

Flow cytometric analysis of k562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat- anti-rabbit secondary antibodies were used for the analysis.

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

This CDC5L antibody is generated from rabbits immunized with a KLH conjugated IMMUNOGEN: synthetic peptide between 187-213 amino acids from the Central region of human CDC5L.

TESTED APPLICATIONS: Flow, WB

For WB starting dilution is: 1:1000 APPLICATIONS: For FACS starting dilution is: 1:10~50

PREDICTED MOLECULAR 92 kDa WEIGHT:

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This antibody is purified through a A column, followed by peptide affinity PURIFICATION: purification.

CLONALITY: Polyclonal

ISOTYPE: Rabbit Ig

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.

CONCENTRATION: batch dependent

Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Info

OFFICIAL SYMBOL: CDC5L

Cell division cycle 5-like protein, Cdc5-like protein, Pombe cdc5-related protein, CDC5L, ALTERNATE NAMES: KIAA0432, PCDC5RP

ACCESSION NO.: Q99459

PROTEIN GI NO.: 73619933

GENE ID: 988

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

The protein is a significant similarity with Schizosaccharomyces pombe cdc5 product, which is a regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was BACKGROUND: also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre- mRNA splicing.

1) Grillari,J., et.al., J. Biol. Chem. 284 (42), 29193-29204 (2009) Zhang,N., et.al., EMBO Rep. REFERENCES: 10 (9), 1029-1035 (2009)

ANTIBODIES FOR RESEARCH USE ONLY.

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