A Value 7 ABO Blood Group System 1752, 1781 AB-Type 89 Abzyme
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Postulated Physiological Roles of the Seven-Carbon Sugars, Mannoheptulose, and Perseitol in Avocado
J. AMER. SOC. HORT. SCI. 127(1):108–114. 2002. Postulated Physiological Roles of the Seven-carbon Sugars, Mannoheptulose, and Perseitol in Avocado Xuan Liu,1 James Sievert, Mary Lu Arpaia, and Monica A. Madore2 Department of Botany and Plant Sciences, University of California, Riverside, CA 92521 ADDITIONAL INDEX WORDS. ‘Hass’ avocado on ‘Duke 7’ rootstock, phloem transport, ripening, Lauraceae ABSTRACT. Avocado (Persea americana Mill.) tissues contain high levels of the seven-carbon (C7) ketosugar mannoheptulose and its polyol form, perseitol. Radiolabeling of intact leaves of ‘Hass’ avocado on ‘Duke 7’ rootstock indicated that both perseitol and mannoheptulose are not only primary products of photosynthetic CO2 fixation but are also exported in the phloem. In cell-free extracts from mature source leaves, formation of the C7 backbone occurred by condensation of a three-carbon metabolite (dihydroxyacetone-P) with a four-carbon metabolite (erythrose-4-P) to form sedoheptulose-1,7- bis-P, followed by isomerization to a phosphorylated D-mannoheptulose derivative. A transketolase reaction was also observed which converted five-carbon metabolites (ribose-5-P and xylulose-5-P) to form the C7 metabolite, sedoheptu- lose-7-P, but this compound was not metabolized further to mannoheptulose. This suggests that C7 sugars are formed from the Calvin Cycle, not oxidative pentose phosphate pathway, reactions in avocado leaves. In avocado fruit, C7 sugars were present in substantial quantities and the normal ripening processes (fruit softening, ethylene production, and climacteric respiration rise), which occurs several days after the fruit is picked, did not occur until levels of C7 sugars dropped below an apparent threshold concentration of ≈20 mg·g–1 fresh weight. -
Biological Values of Cultivated Mushrooms – a Review
Acta Alimentaria, Vol. 48 (2), pp. 229–240 (2019) DOI: 10.1556/066.2019.48.2.11 BIOLOGICAL VALUES OF CULTIVATED MUSHROOMS – A REVIEW J. VETTER* Department of Botany, University of Veterinary Sciences, H-1077 Budapest, Rottenbiller u. 50. Hungary (Received: 3 July 2018; accepted: 11 October 2018) Cultivated mushrooms are not only valuable foods of our age (functional foods) but contain certain benefi cial chemical components (high level of K and P, very low content of Na, considerable quantities of some microelements, high and valuable protein but low fat contents). Some cultivated mushrooms have anti-carcinogenic effects caused fi rst of all by polysaccharides (Lentinan: Lentinula edodes) and by triterpenoids (ganoderic acids: Ganoderma lucidum or unsaturated fatty acids: linoleic, linolenic acids); antidiabetic effects, which can improve the sugar metabolism of patients (Coprinus comatus, Ganoderma lucidum, Agaricus bisporus); anti-microbial effects, caused partly by smaller triterpenoids or by higher molecules, i.e. by direct or indirect effects: via stimulation of the immune system. Certain mushrooms have antioxidant effects, provided mostly by higher radical scavenging activity of phenolic (fl avonoid) components. The chemical composition and its biological effects form together the biological values of the cultivated mushrooms. The following review would like to summarize the most important facts of this topic. Keywords: cultivated mushrooms, chemical components, nutritional values, anti-carcinogenic, antidiabetic, antimicrobial, antioxidant effects Mushrooms have been consumed since earliest historical times; Greeks believed that mushrooms provided strength for warriors, the Romans named them as the “Food of the Gods”. In countries of the Orient, certain mushrooms were believed “elixir of life” etc. -
Shiitake Mushroom: a Tool of Medicine
REVIEW ARTICLE Shiitake Mushroom: A Tool of Medicine Taufiqur Rahman1, MBK Choudhury2 1National Mushroom Development Project, Savar, Dhaka 2Directorate General of Health Services, Dhaka ABSTRACT Medicinal mushrooms have an established history of use in traditional oriental therapies. Contemporary research has validated and documented much of the ancient knowledge. Over the last three decades, the interdisciplinary fields of science that study medicinal mushrooms has sprung up and has increasingly demonstrated the potent and unique properties of compounds extracted from a range of species. Currently, the field is being developed into a very fruitful area. Modern clinical practice in Japan, China, Korea and other Asian countries rely on mushroom-derived preparations. Mushrooms have been studied for nutritional and medical purposes for its various potential anti-tumoral and immunomodulatory componests like polysaccharides that have been identified. For medical purposes, mushrooms have been consumed to prevent cancer and cardiac diseases, to improve blood circulation and to reduce blood cholesterol level. Some of these mushrooms have also been used for the treatment of physical and emotional stress, osteoporosis, gastric ulcers and chronic hepatitis, for the improvement of the quality of life of patients with diabetes and especially for the stimulation of immunity. Shiitake has a history of medicinal uses. The mushroom is used as anticarcinogenic, anti- inflammatory, antioxidant, antifungal, antibacterial, antiviral as well as antithrombotic in cardiovascular disorders. This article has been written to throw some light on Shiitake mushroom which has many nutritional values. Many Shiitake preparations came in market containing the active ingredients which can replace many other marketed synthetic medicines and may prove to have promising results with fewer side effects. -
United States Patent 1191 Lll] 3,983,266 Bahls [451 Sept
United States Patent 1191 lll] 3,983,266 Bahls [451 Sept. 28, 1976 [54] METHOD FOR APPLYING METALLIC 3.776.740 [2/1973 Sivcrz ct al. .......................... .. l06/l SILVER TO A SUBSTRATE OTHER PUBLICATIONS [75] Inventor: Harry Bahls, Wayne, Pa. lvanov et al., Chem. Abs. 43:2548c, I949, [73] Assignee: Peacock Laboratories, Inc., Philadelphia, Pa. Primary Examiner-Ralph S. Kendall [22] Filed: Oct. 9, I974 I 57] ABSTRACT [2!] ,Appl. No.: 513,417 High efficiency deposition of silver on the surface of a substrate is obtained by providing a solution contain [52] [1.8. CI ............................... .. 427/164; 427/165; ing reducible dissolved silver in the presence of an al 427/168; 427/424; 427/426; l06/l kali metal hydroxide and ammonia, all of which are [51] Int. CLZ. ......................................... .. C23C 3/02 applied to the substrate in the presence of an aqueous [58] Field of Search .............. .. l06/l; 427/l68. I69, solution of a moderating reducer containing :1 poly 427/165, I64, 426, 304, 125, 425 hydric alcohol of the formula CH2OH(CHOH),,C H,OH, where n is an integer from 1 to 6. Preferably [56] References Cited the polyhydric alcohol is sorbitol, and in a preferred UNITED STATES PATENTS embodiment a moderator is the form of a thio glycerol is present. 2,996,406 8/l96l Weinrich ........... ............ .. 427/168 3,772,078 ll/l973 Polichcttc ct al ................. .. l06/l X l5 Claims, No Drawings 3,983,266 1 Other objects and advantages of this invention, in METHOD FOR APPLYING METALLIC SILVER TO cluding the economy of the same, and the case with A SUBSTRATE which it may be applied to existing silver coating equip ment and apparatus, will further become apparent BRIEF SUMMARY OF THE INVENTION 5 hereinafter. -
Effect of Intake of Food Hydrocolloids of Bacterial Origin on the Glycemic Response in Humans: Systematic Review and Narrative Synthesis
nutrients Review Effect of Intake of Food Hydrocolloids of Bacterial Origin on the Glycemic Response in Humans: Systematic Review and Narrative Synthesis Norah A. Alshammari 1,2, Moira A. Taylor 3, Rebecca Stevenson 4 , Ourania Gouseti 5, Jaber Alyami 6 , Syahrizal Muttakin 7,8, Serafim Bakalis 5, Alison Lovegrove 9, Guruprasad P. Aithal 2 and Luca Marciani 2,* 1 Department of Clinical Nutrition, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia; [email protected] 2 Translational Medical Sciences and National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham NG7 2UH, UK; [email protected] 3 Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, Queen’s Medical Centre, National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham NG7 2UH, UK; [email protected] 4 Precision Imaging Beacon, University of Nottingham, Nottingham NG7 2UH, UK; [email protected] 5 Department of Food Science, University of Copenhagen, DK-1958 Copenhagen, Denmark; [email protected] (O.G.); [email protected] (S.B.) 6 Department of Diagnostic Radiology, Faculty of Applied Medical Science, King Abdulaziz University (KAU), Jeddah 21589, Saudi Arabia; [email protected] 7 Indonesian Agency for Agricultural Research and Development, Jakarta 12540, Indonesia; Citation: Alshammari, N.A.; [email protected] Taylor, M.A.; Stevenson, R.; 8 School of Chemical Engineering, University of Birmingham, Birmingham B15 2TT, UK Gouseti, O.; Alyami, J.; Muttakin, S.; 9 Rothamsted Research, Harpenden, Hertfordshire AL5 2JQ, UK; [email protected] Bakalis, S.; Lovegrove, A.; Aithal, G.P.; * Correspondence: [email protected]; Tel.: +44-115-823-1248 Marciani, L. -
Traditional Medicine
MINISTRY OF HEALTH DEPARTMENT OF MEDICAL RESEARCH (LOWER MYANMAR) -4 rf,"d .1, l,.ifr M '\t $.,iJ+j AI{I{OTATED BIBLIOGRAPHY OF TRADITIOI{AL MEDTCII\E RESEARCH CARRTED OUT AT DMR (LM) nURIf{G 196s-2011 f# #a# €€# 6rdffi t u 6 l6'6 ktibilicetidiT \ &, ft Ministry of Health Department of Medical Research (Lower Myanmar) Central Biomedical Library ANNOTATED BIBLIOGRAPHY OF TRADITIONAL MEDICINE RESEARCH CARRIED OUT AT DMR (LM) DURING 1965-2011 Compiled by Cho Mar Oo BA (Economics); DipLibSc Librarian, Central Biomedical Library Staff of Central Biomedical Library May Aye Than MBBS, MMedSc (Pharmacology) Deputy Director & Head Pharmacology Research Division Staff of Pharmacology Research Division Aung Myo Min BSc (Physics); DipLibSc; RL Librarian & Head (Retd.) Central Biomedical Library Ye Htut MBBS, MSc (Medical Parasitology) (London) DLSHTM, FRCP (Edin) Deputy Director-General Myo Khin MBBS, MD (New South Wales), DCH, FRCP (Edin) Acting Director General PREFACE Throughout recorded history, people of various cultures have relied on traditional medicine. Worldwide, only an estimated ten to thirty percent of human health care is delivered by conventional, biomedically oriented practitioners. The remaining seventy to ninety percent ranges from self-care according to folk principles, to care given in an organized health care system based on traditional medicine. Likewise, in Myanmar health care system, the existence of traditional medicine along with allopathic medicines is well recognized. Myanmar traditional medicine dates back 2,000 years and is well accepted and widely used by the people throughout history. Burma Medical Research Institute since it was established in 1963 had started a program of research on traditional medicinal plants including laboratory screening tests on animal models of herbs with reputed pharmacological properties-such as anti-dysentery, bronchodilator, hypoglycemic effects. -
In Chemistry, Glycosides Are Certain Molecules in Which a Sugar Part Is
GLYCOSIDES Glycosides may be defined as the organic compounds from plants or animal sources, which on enzymatic or acid hydrolysis give one or more sugar moieties along with non- sugar moiety. Glycosides play numerous important roles in living organisms. Many plants store important chemicals in the form of inactive glycosides; if these chemicals are needed, the glycosides are brought in contact with water and an enzyme, and the sugar part is broken off, making the chemical available for use. Many such plant glycosides are used as medications. In animals (including humans), poisons are often bound to sugar molecules in order to remove them from the body. Formally, a glycoside is any molecule in which a sugar group is bonded through its carbon atom to another group via an O-glycosidic bond or an S-glycosidic bond; glycosides involving the latter are also called thioglycosides. The sugar group is then known as the glycone and the non-sugar group as the aglycone or genin part of the glycoside. The glycone can consist of a single sugar group (monosaccharide) or several sugar groups (oligosaccharide). Classification Classification based on linkages Based on the linkage of sugar moiety to aglycone part 1. O-Glycoside:-Here the sugar is combined with alcoholic or phenolic hydroxyl function of aglycone.eg:-digitalis. 2. N-glycosides:-Here nitrogen of amino group is condensed with a sugar ,eg- Nucleoside 3. S-glycoside:-Here sugar is combined with sulphur of aglycone,eg- isothiocyanate glycosides. 4. C-glycosides:-By condensation of a sugar with a cabon atom, eg-Cascaroside, aloin. Glycosides can be classified by the glycone, by the type of glycosidic bond, and by the aglycone. -
Prebiotics: a Novel Approach to Treat Hepatocellular Carcinoma
Hindawi Canadian Journal of Gastroenterology and Hepatology Volume 2017, Article ID 6238106, 11 pages https://doi.org/10.1155/2017/6238106 Review Article Prebiotics: A Novel Approach to Treat Hepatocellular Carcinoma Naz Fatima,1 Tasleem Akhtar,1 and Nadeem Sheikh1,2 1 Cell and Molecular Biology Lab, Department of Zoology, University of the Punjab, Q-A Campus, Lahore 54590, Pakistan 2Cell and Applied Molecular Biology (CAMB), University of the Punjab, Q-A Campus, Lahore 54590, Pakistan Correspondence should be addressed to Nadeem Sheikh; [email protected] Received 13 February 2017; Accepted 19 April 2017; Published 10 May 2017 Academic Editor: JoseL.Mauriz´ Copyright © 2017 Naz Fatima et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Hepatocellular carcinoma is one of the fatal malignancies and is considered as the third leading cause of death. Mutations, genetic modifications, dietary aflatoxins, or impairments in the regulation of oncogenic pathways may bring about liver cancer.An effective barrier against hepatotoxins is offered by gut-liver axis as a change in gut permeability and expanded translocation of lipopolysaccharides triggers the activation of Toll-like receptors which stimulate the process of hepatocarcinogenesis. Prebiotics, nondigestible oligosaccharides, have a pivotal role to play when it comes to inducing an antitumor effect. A healthy gut flora balance is imperative to downregulation of inflammatory cytokines and reducing lipopolysaccharides induced endotoxemia, thus inducing the antitumor effect. 1. Introduction pathway are deregulated as well, but on a marginal scale. -
Inhibitory Effect and Enzymolysis Kinetics of Lentinan on Α-Glucosidase
Topics in Chemical & Material (TCME) 1(1) (2018 Engineering ) 312-314 Contents List available at VOLKSON PRESS New Materials and Intelligent Manufacturing (NMIM) DOIJournal : http://doi.org/10.26480/icnmim.01.2018. Homepage: https://topicsonchemeng.org.my/ 312.314 ISBN: 978-1-948012-12-6 INHIBITORY EFFECT AND ENZYMOLYSIS KINETICS OF LENTINAN ON Α-GLUCOSIDASE Meifu Wu, Hongli Zhou* School of Chemistry and Pharmaceutical Engineering, Jilin Institute of Chemical Technology, Jilin 132022, China. *Corresponding Author Email: [email protected] This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. ARTICLE DETAILS ABSTRACT Article History: Objective: To study the inhibitory activity and enzymolysis kinetics of lentinan on α-glucosidase. Methods: The enzyme-agent screening model was used to investigate the optimal conditions of α-glucosidase action. In vitro Received 26 June 2018 enzyme kinetics was studied by changing the substrate concentration, reaction time, pH conditions and Accepted 2 July 2018 temperature. Results: The optimal reaction conditions of α-glucosidase were reaction time 120min, reaction Available online 1 August 2018 temperature 50°C, buffer pH 6.0, concentration of substrate PNPG 0.1089 mol/L. Conclusion: 1g/L concentration of lentinan has good inhibitory activity against α-glucosidase, and the inhibitory effect of lentinan is competitive inhibition. KEYWORDS Lentinan, α-glucosidase, enzymolysis kinetics. 1. INTRODUCTION 3. EXPERIMENTAL METHODS Edible fungi are widely used in folk, and their active substances can promote the secretion of insulin and related hormones, so that the 3.1 Determination of enzyme inhibitory activity and function of liver, pancreas and other organs of diabetic patients can return calculation of inhibition rate of enzyme activity to normal [1]. -
Autohydrolysis of Lentinus Edodes for Obtaining Extracts with Antiradical Properties
foods Article Autohydrolysis of Lentinus edodes for Obtaining Extracts with Antiradical Properties Liceth Rocío Huamán-Leandro 1 , María Jesús González-Muñoz 1,2 , Catalina Fernández-de-Ana 3, Arturo Rodríguez-Blanco 3, María Dolores Torres 1,2,* and Herminia Domínguez 1,2 1 Departamento de Enxeñería Química, Universidade de Vigo (Campus Ourense), Edificio Politécnico, As Lagoas, 32004 Ourense, Spain; [email protected] (L.R.H.-L.); [email protected] (M.J.G.-M.); [email protected] (H.D.) 2 CITI-Universidade de Vigo, Tecnopole, San Cibrao das Viñas, 32901 Ourense, Spain 3 Hifas da Terra SL, Portamuiños,7, 36154 Bora Pontevedra, Spain; [email protected] (C.F.-d.-A.); [email protected] (A.R.-B.) * Correspondence: [email protected]; Tel.: +34-988-387-075 Received: 7 November 2019; Accepted: 3 January 2020; Published: 9 January 2020 Abstract: The autohydrolysis of Lentinus edodes was proposed for the extraction of components with antioxidant properties. Operation under non-isothermal conditions was evaluated and compared with isothermal heating. The influence of process severity was assessed in the range of 0.18 to 4.89 (temperature between 50 and 250 ◦C), up to 80% (d.b.) The influence of process severity during the autohydrolysis of Lentinus edodes was assessed in the range 0.3 to 4.89 (temperature between 50 and − 250 ◦C). Up to 80% (d.b.) of the initial raw material could be solubilized at 210 ◦C. The different behavior of the saccharide and phenolic fractions was observed with the treatment temperature. Whereas the highest concentration of the saccharide components (mainly glucooligosaccharides) was found at 210 ◦C, the maximum phenolic yield was identified at 250 ◦C. -
SYNTHESIS and FUNCTIONALITY STUDY of NOVEL BIOMIMETIC N-GLYCAN POLYMERS KA KEUNG CHAN Bachelor of Science Appalachian State Univ
SYNTHESIS AND FUNCTIONALITY STUDY OF NOVEL BIOMIMETIC N-GLYCAN POLYMERS KA KEUNG CHAN Bachelor of Science Appalachian State University May 2014 submitted in partial fulfillment of requirements for the degree of DOCTOR OF PHILOSOPHY IN CLINICAL AND BIOANALYTICAL CHEMISTRY at the CLEVELAND STATE UNIVERSITY May 2021 We hereby approve this dissertation for KA KEUNG CHAN Candidate for the Doctor of Philosophy in Clinical and Bioanalytical Chemistry degree for the Department of Chemistry and Cleveland State University’s College of Graduate Studies by ______________________________________________________ Xue-Long Sun, Ph.D., Dissertation Committee Chairperson Chemistry, 4/22/2021 Department & Date ____________________________________________________________ Aimin Zhou, Ph.D., Dissertation Committee Member Chemistry, 4/22/2021 Department & Date ____________________________________________________________ Bin Su, Ph.D., Dissertation Committee Member Chemistry, 4/22/2021 Department & Date ____________________________________________________________ David Anderson, Ph.D., Dissertation Committee Member Chemistry, 4/22/2021 Department & Date ____________________________________________________________ Moo-Yeal Lee, Ph.D., Dissertation Committee Member Chemical & Biomedical Engineering, 4/22/2021 Department & Date ____________________________________________________________ Aaron Severson, Ph.D., Dissertation Committee Member Biological, Geological and Environmental Sciences, 4/22/2021 Department & Date Date of Defense: 22 APRIL 2021 DEDICATION I dedicate the entirety of this degree to my family. My mother, Mrs. Yu Hung Cheung, to whom I owe the world and I unreservedly dedicate the entire of my life and achievements – thank you for everything that you have done for me. My fiancée, Ms. Mengni Xu, to whom I dedicate the rest of my life with my undying love – you deserve all of my achievements as much as I do. ACKNOWLEDGEMENT I extend my most sincere gratitude to Dr. -
Reports of the Scientific Committee for Food
Commission of the European Communities food - science and techniques Reports of the Scientific Committee for Food (Sixteenth series) Commission of the European Communities food - science and techniques Reports of the Scientific Committee for Food (Sixteenth series) Directorate-General Internal Market and Industrial Affairs 1985 EUR 10210 EN Published by the COMMISSION OF THE EUROPEAN COMMUNITIES Directorate-General Information Market and Innovation Bâtiment Jean Monnet LUXEMBOURG LEGAL NOTICE Neither the Commission of the European Communities nor any person acting on behalf of the Commission is responsible for the use which might be made of the following information This publication is also available in the following languages : DA ISBN 92-825-5770-7 DE ISBN 92-825-5771-5 GR ISBN 92-825-5772-3 FR ISBN 92-825-5774-X IT ISBN 92-825-5775-8 NL ISBN 92-825-5776-6 Cataloguing data can be found at the end of this publication Luxembourg, Office for Official Publications of the European Communities, 1985 ISBN 92-825-5773-1 Catalogue number: © ECSC-EEC-EAEC, Brussels · Luxembourg, 1985 Printed in Luxembourg CONTENTS Page Reports of the Scientific Committee for Food concerning - Sweeteners (Opinion expressed 14 September 1984) III Composition of the Scientific Committee for Food P.S. Elias A.G. Hildebrandt (vice-chairman) F. Hill A. Hubbard A. Lafontaine Mne B.H. MacGibbon A. Mariani-Costantini K.J. Netter E. Poulsen (chairman) J. Rey V. Silano (vice-chairman) Mne A. Trichopoulou R. Truhaut G.J. Van Esch R. Wemig IV REPORT OF THE SCIENTIFIC COMMITTEE FOR FOOD ON SWEETENERS (Opinion expressed 14 September 1984) TERMS OF REFERENCE To review the safety in use of certain sweeteners.