Copyright by Ernesto Lopez 2015
Copyright by Ernesto Lopez 2015 The Dissertation Committee for Ernesto Lopez Certifies that this is the approved version of the following dissertation: The role of arginine vasopressin receptor 2 in microvascular hyperpermeability during severe sepsis and septic shock Committee: Perenlei Enkhbaatar, M.D., Ph.D. Supervisor or Mentor, Chair Jose M. Barral M.D., Ph.D. Donald S. Prough, M.D. Robert A. Cox, Ph.D. Jae-Woo Lee, M.D. _______________________________ David W. Niesel, PhD. Dean, Graduate School The role of arginine vasopressin receptor 2 in microvascular hyperpermeability during severe sepsis and septic shock by Ernesto Lopez, M.D. Dissertation Presented to the Faculty of the Graduate School of The University of Texas Medical Branch in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy The University of Texas Medical Branch 2015 Acknowledgements First I would like to gratefully thank my mentor, Dr. Enkhbaatar for his dedication and support and for giving me the opportunity to work in his lab as a graduate student. Dr. Enkhbaatar helped me to improve my scientific and professional skills with great attention. I had a true opportunity to be exposed to every aspect of the biomedical sciences. Moreover, I would like to express my gratitude to the members of my dissertation committee Dr. Prough, Dr. Cox, Dr. Barral and Dr. Lee as well as Dr. Hawkins, Dr. Herndon, Dr. Rojas and Jacob MS, for all the critiques and ideas that certainly enhanced this project. I would also like to thank to all current and past members of the translational intensive care unit (TICU) for their enormous support and professionalism in completing this project; John Salsbury, Christina Nelson, Ashley Smith, Timothy Walker, Mackenzie Gallegos, Jisoo Kim, Uma Nwikoro, Ryan Scott, Jeffrey Jinkins, Lesia Tower, Cindy Moncebaiz, Cindy Hallum, Lindsey Willis, Paul Walden, Randi Bolding, Jameisha Lee, Mengyi Ye, as well as Drs.
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