2020 Saltin Graduate Course in Exercise and Clinical Physiology, and International Symposium on Molecular and Translational Aspects of Glycemic Health

“Exercise as Medicine: Historical Foundations and Future Directions” Monday October 5 – Thursday October 8, 2020

Pillar and Post Hotel and Conference Centre, Niagara-on-the-Lake, Ontario, Canada https://www.vintage-hotels.com/pillarandpost/

Organizing Committee Robert Boushel, David Wright, Mary-Ellen Harper, Inge Holm, Kathy Manson

Day 1: Monday October 5

Historical Perspectives: Exercise Physiology and the work of Bengt Saltin Chair: Ylva Hellsten, University of Copenhagen

8:00-8:30 Canadian perspective, Robert Boushel, University of British Columbia 8:30-9:00 Danish perspective, Michael Kjær, University of Copenhagen

“Exercise Physiology and Metabolism”

Sex Differences in Metabolism Chair: Cathy Chan, University of Alberta

9:00-9:30 Sex differences in exercise metabolism, Michaela Devries, University of Waterloo 9:30-10:00 Influence of sex and exercise-induced improvements in insulin sensitivity and glycemic control, Jenna Gillan, University of Toronto 10:00-10:30 Metabolic effects of antipsychotics, David Wright, University of Guelph

10:30- 11:00 Coffee Break

Current and Future Perspectives on Cardiovascular and Respiratory Physiology Chair: Jerry Dempsey, University of Wisconsin

11:00-11:30 Respiratory mechanisms, Bill Sheel, University of British Columbia 11:30-12:00 The microcirculation, Graham Fraser, Memorial University 12:00-12:30 Muscle blood flow regulation, Ylva Hellsten, University of Copenhagen

12:30-1:30 Lunch

1:30-2:30 Workshop on Science Communication Morten Zacho, Rigshospitalet, Copenhagen, Denmark

Historical to Current Perspectives in Neuromuscular Research Chair: Kevin Shoemaker, Western University

2:30-3:00 Neural control of muscular function, Jayne Kalmar, Wilfred Laurier University 3:30-4:00 Muscular fatigue, Niels Ørtenblad, University of Southern Denmark

4:00-7:00 Group outing to Niagara Falls

7:30-8:30 Dinner

Evening: local pubs or theatres

Day 2: Tuesday October 6

Methodological Considerations in Metabolic Research Chair: André Carpentier, Université de Sherbrooke

8:30-9:00 Measuring parameters in glucoregulation, Jonathan Little, University of British Columbia 9:30-10:00 Imaging of tissue and cellular structures TBA 10:00-10:30 Mitochondrial energetics, Mary-Ellen Harper, University of Ottawa

10:30-11:00 Coffee

Adipose Tissues and Lipid Metabolism Chair: Jane Shearer, University of Calgary

10:30-11:00 Brown adipose tissue, André Carpentier, Université de Sherbrooke 11:00-11:30 Incretin Control of Lipid Metabolism, Erin Mulvihill, University of Ottawa 11:30-12:00 TBA

12:00-1:00 Lunch

1:00-2:30 Student Posters, led by Chris Perry (Jonathan Little, Gianne Parise, Jenna Gillen, Niels Ørtenblad, Graham Fraser, Jane Shearer) (with Coffee)

3:00-6:00 Visit Niagara Wineries

6:30-7:30 Dinner

Evening: Options include local pubs or Theatre https://www.shawfest.com/playbill/gypsy/

Day 3: Wednesday October 7 Neuromuscular Physiology Chair: Jayne Kalmar, Wilfred Laurier University

8:30-9:00 Exercise and muscle activation, Jeff Power, University of Guelph 9:00-9:30 Satellite cells regulation of muscle adaptation, Gianni Parise, McMaster University Michael Kjær?

Exercise and the Brain Chair: Bente Klarlund Pedersen, Rigshospitalet

9:30-10:00 Exercise and Brain health, Rebecca MacPherson, Brock University

10:00-10:30 Exercise and brain circuitry, Kevin Shoemaker, Western University

10:30-12:00 Student Posters, led by Dr. Chris Perry and faculty (with Coffee)

12:00-1:00 Lunch

Exercise, Nutrition and the Gut Chair: Jenna Gillen, University of Toronto

1:00-1:30 Microbiome, André Tchernof, Université Laval 1:30-2:00 Nutrition, Cathy Chan, University of Alberta 2:00-2:30 Nutrition-Gut interactions, Jane Shearer, University of Calgary

2:30-3:00 Coffee

Teaching and Communications Chair, Jerry Dempsey, University of Wisconsin

3:00-3:30 Teaching Exercise Physiology, Chris Perry, York University 3:30-4:30 Student Exercise in Communications, Morten Zacho, Rigshospitalet, Copenhagen

4:30-5:00 Course Evaluation

5:00-7:00 Exercise/Recreation Break

7:00-8:00 Gala Dinner and Student Awards

Day 4: Thursday October 8 International Symposium on Molecular and Translational Aspects of Glycemic Health

Prince of Wales Hotel, Royal Cambridge Ballroom https://www.vintage-hotels.com/princeofwales/

8:45-9:00 Symposium Introduction Mary-Ellen Harper, University of Ottawa

9:00-10:00 Exercise as Medicine: Myokines Bente Klarlund Pedersen, Rigshospitalet, Copenhagen, Denmark Introduction by Mary-Ellen Harper

10:00-11:00 Title: Fuel supply, mitochondrial function and insulin sensitivity Daryl Neufer, East Carolina Diabetes and Obesity Institute Introduction by Chris Perry

11:00-12:00 TGFb2 Exercise and Adipose Tissues Laurie Goodyear, Harvard University Introduction Michael Kjær, University of Copenhagen

12:00-1:00 Lunch

1:00-2:00 GLP1 and Novel Approaches for the Treatment of Type 2 Diabetes, Daniel Drucker, University of Toronto Introduction by David Wright

2:00-2:30 Panel Discussion: Laurie Goodyear, Daryl Neufer, Dan Drucker Moderators: David Wright, Mary-Ellen Harper