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Cet-2019 Ug Neet List of Canidates Eligible for Names List Admission

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CET-2019 UG NEET LIST OF CANIDATES ELIGIBLE FOR NAMES LIST ADMISSION THROUGH COLLEGE CET NO CANDIDATE NAME CATEGORY AI_RANK AA021 MOHAMMED SALMAN GM 247849 AA022 SUPRIYA R GM 309432 AA029 SAMIKSHA K GM 155841 AA032 HITHAISHI D N SCG 443391 AA034 APEKSHA V SATTARI GM 341420 AA048 DILIP RAJ C 1G 284302 AA052 NISARGA R K 2AG 754612 AA072 GOLLAPALLI N V SRIKAR MURTHY GM 308615 AA081 S P NANDINI GM 648933 AA083 HAMSA NAGARAJ 3AG 228322 AA088 SAMRUDH N 3AG 327081 AA116 SAHANA P 3BG 745229 AA118 ABHINAV ANIL GM 243372 AA123 UDAY MALAKASHETTY 2AG 235847 AA124 K N PAVAN STG 371985 AA134 VIDYASHREE N 2AG 317408 AA139 NEHA G SCG 578950 AA145 QURRATH UL AIN 2BG 729559 AA152 POORNIMA R 3AG 366886 AA155 GOWTHAMI G N 3AG 302198 AA156 DEEKSHA MURALI GM 184644 AA173 MOHIT KASHYAP GMN 299635 AA192 SAHANA NC 3AG 538487 AA212 JYOTHSNA M G 2AG 680359 AA227 MINHAJ KHAN 2BG 513655 AA282 HARSHITHA C N 3AG 241794 AA299 JYOTHI N 2AG 632502 AA303 R BINU SCG 678864 AA311 SUHAS REDDY B R GM 392809 AA331 SYED HARIS 2BG 590026 AA332 VAISHNAVI A 1G 303953 AA335 PRAMOD C S 3BG 734888 AA351 MANJUNATH A 2AG 276018 AA360 DIVYASHREE N 3AG 711854 AA378 KARTHIK N MIRAZKAR 2AG 726186 AA380 S SWETHA SHREE SCG 264354 AA391 TULSI RAJU V 1G 268019 AA395 ANUSHA S G 2AG 524717 AA401 AJITH D M SCG 332046 AA405 RAGHAVENDRA C 2AG 387546 AA409 COLIN PAUL OPN 420163 AA410 MELNA THOMAS OPN 205667 AA411 NIDA FATHIMA 2BG 595160 AA412 ANUSHA C 3BG 362828 AA417 SREYA SURESH P OPN 468963 AA420 MEGHANA R 3AG 150243 AA423 MOHAMMED AFFAN GM 247270 AA424 VARSHA M ASHOK GM 329866 AA427 SITHARA N OPN 96647 AA428 PRERNA TRIPATHY GM 401194 Page 1 of 638 CET-2019 UG NEET LIST OF CANIDATES ELIGIBLE FOR NAMES LIST ADMISSION THROUGH COLLEGE AA431 PRAGYA J ARYA GM 577255 AA439 AHMED TAHA 2BG 289578 AA442 AMATHUL AHAD 2BG 442446 AA444 BEVIN STANELY OPN 619261 AA446 VASUDHA KRISHNAN NAIR OPN 232312 AA447 JENIFFA HARRIOT S OPN 416008 AA449 RAGHAVENDRA R 2AG 282009 AA450 ANILA K S OPN 58141 AA458 SALOOJA LATHEEF OPN 69431 AA464 ANUSHA R 3AG 167194 AA467 MANOGNA S GM 199558 AA469 ANN MARY THOMAS OPN 28869 AA470 ANJANI HIRANYA ACHANTA OPN 202957 AA471 RIDA KHAN 2BG 352437 AA472 SHALU ABRAHAM 3BG 754346 AA477 FIDHA FATHIMA OPN 281300 AA478 VINOD KUMAR M SCG 195590 AA480 ASWIN P P OPN 210817 AA481 SANSKRITI BASANTH GURAPPA OPN 465751 AA482 BULBUL SINGH GM 197954 AA484 ROSHINI VINOD SADANATH SURENDRANOPN 40634 AA485 AMULYA K H M GM 135976 AA486 THUSHAR N SCG 363103 AA491 AMANDA ROSE THOMAS OPN 60086 AA493 CHARABASAVA 2AG 166972 AA494 SREELEKHA K 3BG 428266 AA496 YOGESH D 3BG 214561 AA506 MUATHAZ HASSAN MOIDU OPN 214140 AA518 HARPUDE RUTUJA KISAN OPN 170722 AA519 MOHAMMED GAYAS S OPN 364362 AA520 SARIL YADAV OPN 30305 AA524 ARYAN KUMAR SRIVASTAVA OPN 40313 AA525 KANUPURI LEENA OPN 86560 AA531 YAMINI OPN 25992 AA532 MEHUL SINGH SAINI OPN 46867 AA535 PRITAM KUMAR OPN 53698 AA538 SIRAJ B SIYAD OPN 24255 AA540 KADIYALA VENKATA SAI PAVANA OPN 349879 AA544 ANKITA SINGH OPN 102561 AA545 PREETHA M 3AG 362258 AA546 MALAVIKA M OPN 128481 AA549 JERIC JAIMON OPN 86629 AA551 VAISHNAVI GOYAL OPN 31412 AA552 SREERAM E S OPN 106860 AA555 RAKSHIT OPN 119878 AA556 TUSHAR OPN 286096 AA557 SYED MOHAMMED NOORUN NABI OPN 229185 AA560 BHAD ANUJ GAJANAN OPN 93724 AA561 JAFLIN L GRITTLE OPN 316563 AA565 BOBBY CHUNGATH OPN 88946 AA567 CHRISANN AROC MARWIN J OPN 197375 Page 2 of 638 CET-2019 UG NEET LIST OF CANIDATES ELIGIBLE FOR NAMES LIST ADMISSION THROUGH COLLEGE AA569 STEPHINA LIZETTE SEBASTIAN OPN 111842 AA570 SREEDEVI K MENON OPN 295411 AA574 DURGA PUJITHA KORIVI OPN 219622 AA575 V THARUN KUMAR OPN 564474 AA577 DEVANA MENON C OPN 72116 AA586 S HARIPRASAD OPN 172737 AA587 ARUBA KHAN MOHAMMADI K A 2BG 452680 AA589 JAYA CHITHRA DEVI R S OPN 138563 AA592 ADITI SAMMI OPN 52661 AA596 APARNA SURESHKUMAR PILLAI OPN 19103 AA597 DHIVYA DHARSHINI R OPN 461963 AA599 MERIL SUSAN SAM OPN 33345 AA602 ASHLEY THOMAS MATHEN OPN 34635 AA608 PAYAL SAHA OPN 143494 AA612 JASLINE INIYA A OPN 421789 AA616 ARGHYADYUTI GANGULY OPN 22478 AA617 SHABNA MA OPN 90596 AA622 DORNALA SHIVA OPN 163866 AA623 AKULA NAGA VENKATA ARUNA KIRANOPN 628132 AA624 SHIVANGI PRIYA OPN 181337 AA625 RENISH GANDHI S P OPN 324999 AA628 MOHAMMAD HASSAN BIN OZAIR OPN 88511 AA631 SUSAN SHIBU OPN 103386 AA632 CALEB SHALOM JAYAKUMAR OPN 190335 AA633 AMAN RAZIQ OPN 682390 AA641 ADITI YADAV OPN 42645 AA643 PRIYANKA KOLAKAR 1G 209858 AA646 SHIVANI OPN 65447 AA648 MUNNANGI MANASA PRASHANTHI OPN 96769 AA650 MALLARAPU KUSUMA OPN 253939 AA653 HARSHALINI S R OPN 631693 AA654 SNEHA SUNILKUMAR OPN 56067 AA659 ADITI DWIVEDI OPN 25422 AA660 JENNIFER B STEPHENS OPN 116433 AA661 PRATIBHA YADAV OPN 39946 AA662 PRETTY R H OPN 386547 AA664 SREYESKRISHNAN SHAJEEV OPN 36096 AA674 ADITHYA P OPN 236472 AA676 MUHAMMED QASIM MEHABOOB OPN 72502 AA678 ANUSHIKA SV OPN 527997 AA683 ABHISHEK SHARMA OPN 675177 AA689 SIDHARTH NAIR P OPN 103406 AA690 K VAISHNAVI HARI RAJ OPN 268694 AA696 ANN ARMSTRONG OPN 28909 AA698 SAI SUDHINDRA BABU KUSU OPN 124625 AA704 A S APARNA OPN 242128 AA706 PAUL THOMSON OPN 316864 AA708 ANIL KUMAR NIMAWAT OPN 35444 AA715 MADHUMITHA B OPN 218045 AA718 RAJTILAK SENGUPTA OPN 668029 AA719 JAWID MISBAH OPN 371565 Page 3 of 638 CET-2019 UG NEET LIST OF CANIDATES ELIGIBLE FOR NAMES LIST ADMISSION THROUGH COLLEGE AA722 ISHITA SINHA OPN 418594 AA725 DALVI ARIBA OPN 486943 AA726 KEVIN JOSE MANIPPADAM OPN 74936 AA729 OJASWINI TUTU JK 219768 AA730 PRAGYANSISH PRABHANJAN BISWALOPN 256965 AA731 SERMON BEHERA OPN 389662 AA732 AISHWARYA PRASAD BHASKARAN OPN 59321 AA734 SANDEEP VATSA OPN 35228 AA740 PRIYADHARSHINI T V OPN 217388 AA742 AKSHIT KUMAR CHEERALA OPN 67930 AA746 NANDU V NAIR OPN 216722 AA748 JUANIKA VALAN V P OPN 382773 AA750 K SAI HARSHITHA OPN 75013 AA760 ISHA VERMA OPN 33725 AA761 ANJU SUSAN ITTY OPN 87157 AA765 SAMROODA KHADER OPN 129424 AA774 NAVANEETH VYAS OPN 53141 AA780 VARSHA RAJAN OPN 25874 AA781 HANNATH SHAKIRA G OPN 115255 AA783 DEVENDRA PATEL OPN 12664 AA793 ABHILASHA OPN 415652 AA794 SREELAKSHMI S OPN 43734 AA796 DHRUV OPN 662281 AA798 CHINMAY SUNDAS OPN 344815 AA800 RAABI RISO PATOR OPN 422041 AA801 KHUSHI OPN 33956 AA805 RHYTHM SANYAMI OPN 89537 AA806 LOGA SRI G OPN 251590 AA808 KRUTIKA KHANNA OPN 70046 AA809 KHAN AARSHE SHAFIQUE OPN 540821 AA812 HARSHIT KUMAR PRABHAKAR OPN 40096 AA815 RAYVIN A S OPN 308188 AA816 KAUSTUBH SHARMA OPN 60459 AA817 MANISH PRAJAPATHI 2AG 180299 AA827 JOCKY J MALAYIL OPN 77668 AA829 SHREYA SRIDHAR OPN 38450 AA830 BODIGIRI BHAGYA LAKSHMI OPN 179000 AA831 MANSI MITTAL OPN 22480 AA832 ALOK KUMAR SINGH OPN 38184 AA834 SANA MARIAM JOSEPH OPN 73702 AA835 MANASVI RAMPAL OPN 58233 AA840 ATUL CHAUDHARY OPN 25034 AA843 SAMANTHA SAJEEV OPN 47013 AA845 KRISHNA SAJEEVAN OPN 66131 AA846 ROHIT RAMACHANDRAN OPN 25746 AA847 RITIKA KUMARI OPN 513869 AA848 NIVEDITA K B OPN 165575 AA850 TISHYA MUJOO JK 4010 AA851 DHIYA SHIJU K OPN 300768 AA854 SATHULURI POOJITHA CHOWDARY OPN 227933 AA855 MD ABSARUL HODA OPN 125149 Page 4 of 638 CET-2019 UG NEET LIST OF CANIDATES ELIGIBLE FOR NAMES LIST ADMISSION THROUGH COLLEGE AA858 UBAIDULLA 1G 540707 AA859 SRAVYA M V OPN 66412 AA860 KESHAV SAIN OPN 16519 AA861 EMIMA TIMI J OPN 435194 AA862 SIBARAM DASH OPN 90640 AA864 ABINAYA R V OPN 386424 AA865 NANDIKA NAD ENGOOR OPN 257573 AA871 JOHN VARGHESE OPN 32286 AA872 NARGHEEZ NASSARUDEEN OPN 168241 AA874 NAINIKA RAI OPN 36139 AA875 ARNAV BANSAL OPN 106840 AA876 TRIPTI SINHA OPN 39447 AA879 NIRANJAN KUMAR OPN 178959 AA881 S VASUDEVAN OPN 143430 AA884 SNEHA SAMUDRALA GM 553306 AA885 FAHAD ANJUM OPN 500330 AA887 NANDANA MOL K S OPN 111043 AA890 PURNAMRITA PARASHAR OPN 79547 AA897 TINCY MOL THOMAS OPN 482860 AA899 AYAN MALLICK OPN 447002 AA905 JOSHMI JAN S S OPN 321531 AA912 SRABASTI PATTANAYEK OPN 28702 AA913 FIDA NAZREEN OPN 27988 AA932 SHAURYA BAWEJA OPN 28630 AA933 DHENGRE TANVI SANJAY OPN 410539 AA934 NANDITHA RAJAMANI GM 214850 AA936 SHAIKH ZAINAB KHALID QAMAR OPN 432421 AA938 KASANNAGARI GURU VENKATA SAI ROOPESHOPN 144269 AA940 JESLIN LU ALEX OPN 610662 AA945 M S ADERSH OPN 213208 AA946 ANU MARIA SABU OPN 102323 AA947 NIMMAGADDA YASASWINI OPN 37062 AA948 AMAN KHANNA OPN 52833 AA949 NIRMAL SINGH OPN 487647 AA953 NUR SEIKH OPN 156876 AA959 YASHASHVI KHATROTH OPN 173515 AA960 SRUTHI JOHNSON OPN 35255 AA962 SANTHIYA S OPN 88979 AA963 RESHMA MARIA JACOB OPN 343067 AA964 VASU AGARWAL OPN 67321 AA965 MEGHA BANSAL OPN 213542 AA966 GANGINENI ANUSREE OPN 218721 AA970 AKUL SAJI KUMAR OPN 75445 AA971 ABHINAV RANJAN OPN 22807 AA975 CYRIL JOY OPN 61408 AA977 HELOISE MATHEW OPN 23363 AA980 SHWETA PANDEY OPN 192204 AA981 ROSHAN S OPN 339614 AA982 WASIM RAHMAN OPN 357850 AA983 A SUSHMITHA SREE OPN 433146 AA986 AAYUSHI RAJEEV GUPTA OPN 598380 Page 5 of 638 CET-2019 UG NEET LIST OF CANIDATES ELIGIBLE FOR NAMES LIST ADMISSION THROUGH COLLEGE AA987 MOHAMMAD DANISH IQBAL OPN 68332 AA994 NIKSHAP PANDITA JK 98435 AA997 YAMINI P SCG 816338 AB019 POOJA NARESH SCG 303722 AB045 STUTI KAMDAR GM 237780 AB059 MONISHA S GM 334044 AB062 ERYKAH KAVERI EPHREM MONTEIROGM 472726 AB077 PREETHI SINGH M 2AG 395189 AB081 HEMASHREE D S GM 254328 AB086 MOHITH C S 3BG 291032 AB091 N MANJUNATH 2AG 291317 AB097 SHRADDHA B GM 218092 AB108 E MONICA SHARON GM 440626 AB125 ANUSHA B K 3BG 147056 AB146 N HITESH SCG 507640 AB164 RAKSHITH B P 3AG 126545 AB168 M YOGISH 1G 244048 AB172 BHAGAVANTHARAY ALLAGI 2AG 430233 AB192 SOWNDARYA N 3BG 506811 AB241 MANASA A 3AG 494147 AB251 P RADHA RAI 1G 516518 AB266 LIKITHA G 2AG 285947 AB275 BINDHU M SCG 415933 AB281 SUHAS R SCG 720673 AB286 KUSHI K S GM 545028 AB288 MEGHANA N 3AG 282775 AB313 GEETHA V SCG 474494 AB337 CHARAN BABU V 2AG 354973 AB340 PURNASHREE M SCG 509805 AB348 NEELANJANA
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    Purampokku Full Movie In Tamil Hd 1080p Purampokku Full Movie In Tamil Hd 1080p 1 / 3 2 / 3 Purampokku (2015 Telugu) Watch Full Movie Online DVD HD TodayPk Movies ... 2015 Tamil BluRay HD Movies: Tamil BD50, 720p, 1080p, BDRips (Old& New) .... You can watch online video streaming in HD excellent in 159 Min length. Watch full ... Full Length of Purampokku Engira Podhuvudamai in HD Quality 1080p .. Dora Full Movie, Dora movie Online, Dora tamil. , Purampokku Video Songs Download, Purampokku Tamil Movies 2016 Full Movie HD 1080p Blu Ray # Tamil .... Purampokku (2015)-Tamil Movie Full Mp3 Songs Free Download latest tamil mp3 songs free ... Purampokku (2015) Tamil Movie Watch Full HD Arya, Vijay Sethupathi, Shaam, Karthika Nair ... Purampokku - Purampokku (2015)1080p. Tamil .... ... Full Movie Download Purampokku Engira Podhuvudamai HD Movie Download Moviesda. ... Purampokku Engira Podhuvudamai (2015) Movie Poster ... Full Movie 1080p HD & 720 HD TamilRockers TamilGun Download .... Full MoviePurampokku Engira Podhuvudamai (2015)With HD Quality. ... Watch Full Purampokku Engira Podhuvudamai in Best Video Format. Now you can enjoy ... Free Streaming Purampokku Engira Podhuvudamai in HD Video 1080p .. Pictures from the Tamil movie Purampokku Engira Podhuvudamai, starring .... Simbu(Silambarasan) Latest HD Photos/Wallpapers (1080p) ... Full Movies 2HD.. Hara hara mahadevaki full movie. Watch purokku engira podhuvudamai (2015) dvd hd 1080p tamil full movie watch online free. Telugu movies back ground .... Purampokku HD Movie Download TamilRockers Purampokku Tamil Movie ... Movie Download 1080p Rajj Rebot Full Purampokku Engira Podhuvudamai Tamil.. Purampokku Engira Podhuvudamai 1080p Video Songs Download, Purampokku Engira Podhuvudamai 1080p HD Video Songs Download, Purampokku .... Karthika Nair Hot In Purampokku Tamil Movie, Karthika Nair Hot Navel In ..
  • National Law University, Delhi Sector-14, Dwarka New Delhi-110078

    National Law University, Delhi Sector-14, Dwarka New Delhi-110078

    NATIONAL LAW UNIVERSITY, DELHI SECTOR-14, DWARKA NEW DELHI-110078 ALL INDIA LAW ENTRANCE TEST-2016 (AILET-2016), B.A. LL.B.(HONS.) RESULT Marks Wise S.No. Roll No Name of the Candidate Name of Father/Mother/ Guardian DoB Gender Marks 1 52788 KARAN DHALLA DEEPESH DHALLA 03/02/1998 M 119 2 55979 SHUBHAM JAIN BHUPENDRA JAIN 20/11/1997 M 116 3 56876 VANSH AGGARWAL PAWAN SINGHAL 25/03/1998 M 116 4 63245 ARTH NAGPAL RAJESH NAGPAL 28/08/1997 M 114 5 64122 RIJU SHRIVASTAVA YUGENDRA ARYA 27/04/1998 F 114 6 69185 ROHIL BIPIN DESHPANDE BIPIN GAJANAN DESHPANDE 10/05/1998 M 114 7 70191 ARVIND KUMAR TIWARI AKHILESH CHANDRA TIWARI 03/10/1997 M 114 8 75260 ANUBHUTI GARG ARUN GARG 13/06/1997 F 114 9 63398 EKANSH ARORA RAJESH ARORA 08/01/1997 M 113 10 66089 KARISHMA KARTHIK KARTHIK SUBRAMANIAN 06/04/1998 F 113 11 75266 ANUNA TIWARI SANJAY TIWARI 14/08/1997 F 113 12 77055 ANMOL DHAWAN SANJEEV DHAWAN 29/12/1998 M 113 13 77061 ANUKRITI KUDESHIA ANURODH KUDESHIA 27/09/1997 F 113 14 64048 PRANSHU SHUKLA SANJAY SHUKLA 24/02/1998 M 112 15 71044 NIKHIL SHARMA PRAMOD KUMAR SHARMA 21/01/1997 M 112 16 75365 AVANI AGARWAL SURENDRA KUMAR AGARWAL 28/06/1998 F 112 17 63385 DIVYA KUMAR GARG NITIN GARG 05/04/1998 M 111 18 64071 PRIYANKA CHATURVEDI D. P. CHATURVEDI 20/02/1997 F 111 19 72316 PRITHVI JOSHI ARUN JOSHI 28/10/1998 M 111 20 74213 SHIVAM SINGHANIA SUNIL SINGHANIA 27/02/1998 M 111 21 74227 SHREYA JAIPURIA BIRENDRA JAIPURIA 22/12/1997 F 111 22 77417 SREEDEVI GOPALAKRISHNAN NAIR GOPALAKRISHNAN NAIR 01/07/1997 F 111 23 50911 ANKUR SINGHAL ANIL KUMAR SINGHAL 26/12/1997
  • Current Affairs Questions and Answers for February 2010: 1. Which Bollywood Film Is Set to Become the First Indian Film to Hit T

    Current Affairs Questions and Answers for February 2010: 1. Which Bollywood Film Is Set to Become the First Indian Film to Hit T

    ho”. With this latest honour the Mozart of Madras joins Current Affairs Questions and Answers for other Indian music greats like Pandit Ravi Shankar, February 2010: Zakir Hussain, Vikku Vinayak and Vishwa Mohan Bhatt who have won a Grammy in the past. 1. Which bollywood film is set to become the first A. R. Rahman also won Two Academy Awards, four Indian film to hit the Egyptian theaters after a gap of National Film Awards, thirteen Filmfare Awards, a 15 years? BAFTA Award, and Golden Globe. Answer: “My Name is Khan”. 9. Which bank became the first Indian bank to break 2. Who becomes the 3rd South African after Andrew into the world’s Top 50 list, according to the Brand Hudson and Jacques Rudoph to score a century on Finance Global Banking 500, an annual international Test debut? ranking by UK-based Brand Finance Plc, this year? Answer: Alviro Petersen Answer: The State Bank of India (SBI). 3. Which Northeastern state of India now has four HSBC retain its top slot for the third year and there are ‘Chief Ministers’, apparently to douse a simmering 20 Indian banks in the Brand Finance® Global Banking discontent within the main party in the coalition? 500. Answer: Meghalaya 10. Which country won the African Cup of Nations Veteran Congress leader D D Lapang had assumed soccer tournament for the third consecutive time office as chief minister on May 13, 2009. He is the chief with a 1-0 victory over Ghana in the final in Luanda, minister with statutory authority vested in him.
  • Sangram Kendra

    Sangram Kendra

    Sangram Kendra District Taluka Village VLE Name Akola Akola AGAR PRAMOD R D Akola Akola AKOLA N KASHIRAM A Akola Akola AKOLA JP Shriram Mahajan Akola Akola AKOLA NW RP Vishal Shyam Pandey Akola Akola AKOLA NW RP-AC1 Vishal Shyam Pandey Akola Akola AKOLA OPP CO Dhammapal Mukundrao Umale Akola Akola AKOLA OPP CO-AC1 Dhammapal Mukundrao Umale Akola Akola AKOLA RP Rahul Rameshrao Deshmukh Akola Akola ANVI 2 Ujwala Shriram Khandare Akola Akola APATAPA Meena Himmat Deshmukh Akola Akola BABHULGAON A Jagdish Maroti Malthane Akola Akola BHAURAD MR Jagdish Gulabrao Deshmukh Akola Akola BORGAON M2 Amol Madhukar Ingale Akola Akola BORGAON MANJU N NARAYANRAO A Akola Akola DAHIHANDA RAJESH C T Akola Akola GANDHIGRAM Nilesh Ramesh Shirsat Akola Akola GOREGAON KD 2 Sandip Ramrao Mapari Akola Akola KANSHIVANI Pravin Nagorao Kshirsagar Akola Akola KASALI KHURD Kailash Shankar Shirsat Akola Akola KAULKHED RD DK Jyoti Amol Ambuskar Akola Akola KHADKI BU Kundan Ratangir Gosavi Akola Akola KHARAP BK Ishwar Bhujendra Bhati Akola Akola KOLAMBHI Amol Balabhau Badhe Akola Akola KURANKHED Sanjeevani Deshmukh Akola Akola MAJALAPUR Abdul Anis Abdul Shahid Akola Akola MALKAPUR V RAMRAO G Akola Akola MAZOD Sahebrao Ramkrushna Khandare Akola Akola MHAISANG Bhushan Chandrashekhar Gawande Akola Akola MHATODI Harish Dinkar Bhande Akola Akola MORGAON BHAK Gopal Shrikrishna Bhakare Akola Akola MOTHI UMRI A BHIMRAO KAPAL Akola Akola PALSO Siddheshwar Narayan Gawande Akola Akola PATUR NANDAPUR Atul Ramesh Ayachit Akola Akola RANPISE NAGAR Shubhangi Rajnish Thakare Akola Akola
  • Lens Epithelium Derived Growth Factor (1-326): A

    Lens Epithelium Derived Growth Factor (1-326): A

    LENS EPITHELIUM DERIVED GROWTH FACTOR (1-326): A NEW PROTEIN DRUG FOR RETINAL DISEASES By RINKU BAID B.Pharm. (Honors), Jadavpur University, 1997 A thesis submitted to the Faculty of the Graduate School of the University of Colorado in partial fulfillment of the requirements for the degree of Doctor of Philosophy Pharmaceutical Sciences 2013 This thesis for the Doctor of Philosophy degree by Rinku Baid has been approved for the Pharmaceutical Sciences Program by Latoya Jones Braun, Chair Uday B. Kompella, Advisor J Mark Petrash Dhinakar Kompala Krishna Mallela Date: 08/14/2013 ii Baid, Rinku (Ph.D., Pharmaceutical Sciences) Lens Epithelium Derived Growth Factor (1-326): A New Protein Drug for Retinal Diseases Thesis directed by Professor Uday B. Kompella ABSTRACT Although over 2.2 million people in the United States suffer from dry age related macular degeneration and retinitis pigmentosa, there are no FDA approved therapeutic agents. Lens epithelium derived growth factor (LEDGF), a transcription factor that promotes cell survival, although effective in reducing retinal degeneration, has a binding domain for the HIV integrase. To overcome this limitation, which promotes HIV infection, the purpose of this study was to design a fragment of LEDGF as a novel therapy for treating retinal degenerative diseases. Further, we hypothesized that the novel fragment of LEDGF is useful in treating protein aggregation disorders such as retinitis pigmentosa and that nanoassemblies of this protein can offer enhanced stability, delivery, and activity, while prolonging drug delivery. We designed and synthesized LEDGF1-326 as a new protein to avoid HIV integrase interactions of LEDGF, assessed its ability to reduce P23H rhodopsin protein aggregation induced stress, prepared stable formulations including nanoassemblies and assessed their cellular entry and in vivo delivery and efficacy.