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65Th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017)

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65Th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017) Abstracts | GA 2017 65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017) Date/Venue: Chair: 3.–7. September 2017, Basel, Switzerland Prof. Dr. Matthias Hamburger Prof. Dr. Veronika Butterweck, Basel Editorial Veterinary Medicine Satellite Symposium Basel, Sunday, September 3, 2017 th Abstracts of the Veterinary Medicine Satellite Symposium Abstracts of the 65 Annual Meeting of the Society for - in order of appearance Medicinal Plant and Natural Product Research (GA) From September 3 rd to 6th 2017 over 600 participants from more than 30 Su-Veterinary Medicine Satellite Symposium-KNL-01 countries gathered in Basel, Switzerland, for the 65th Annual Meeting of the Recent challenges in veterinary pharmacotherapy – Society for Medicinal Plant and Natural Product Research. could medicinal plants be an option? The main scientific topics of the conference were 1 2 3 3 1 ▪ Bioactive Natural Products Authors Naegeli H , Mevissen M , Walkenhorst M , Ayrle H , Kupper J ▪ Dermatology and Dermatocosmetics Institute 1 Institute of Veterinary Pharmacology and Toxicology, University of ▪ Functional Foods Zurich, Zurich, Switzerland; 2 Division of Veterinary Pharmacology and ▪ Biosynthesis and Biotechnology Toxicology, University of Berne, Berne, Switzerland; 3 Department of Livestock ▪ Sustainable Use of Natural Products Sciences, Research Institute of Organic Agriculture (FiBL), Frick, Switzerland ▪ Natural Product Formulation and Nanotechnolology DOI 10.1055/s-0037-1608012 ▪ Analytical Studies, Natural Product Chemistry & Computational approaches One major challenge in veterinary pharmacotherapy is the currently still ex- ▪ Quality control methods for herbal extracts, starting materials and natural cessive use of antimicrobials. European countries banned the misuse of anti- products microbials as growth promoters, but it is recognized that their remaining ▪ Phytopharmacology/Extract Pharmacology widespread application for the prevention and treatment of diseases in farm ▪ Animal health care and Veterinary phytomedicine as well as companion animals is a main driver of antibiotic resistance. A The scientific programme of the Main Conference included 5 plenary lectures primary concern is that the antimicrobial use in veterinary medicine contri- by invited speakers, 4 award lectures, 96 contributed short lectures and 545 butes to reduce efficacies in humans. Cases of transmission of acquired resis- posters. The short lectures were held in three parallel sessions, and the two tances from animals to humans have been described, although the impor- poster sessions on Monday and Tuesday provided a forum for lively scientific tance and extent of this resistance spread has yet to be quantified. Another discussions. concern is the increasing antibiotic resistance detected in zoonotic bacteria, On Sunday, 3rd September, three pre-congress events took place. The Young but the potential for transmissions extends to commensals and opportunistic Researchers Workshop offered a platform for young scientists to present their bacteria. These issues are further aggravated by the fact that many antimi- latest findings, and the Regulatory Affairs Workshop served as a forum for crobials used in veterinary medicine are critically important for the manage- industry to update on the latest trends in regulation of phytomedicines and ment of life-threatening infections in humans. Even in the presence of a related areas. A Pre-congress Symposium on Veterinary Phytotherapy was bacterial infection, the use of antimicrobials is not always justified. Steward- organized by the Swiss Medical Society for Phytotherapy (SMGP), in coopera- ship programs advocate that the treatment of infections should not necessa- tion with the GA Networking Group on Animal Healthcare and Veterinary rily involve antimicrobials in diseases that are self-limiting or can be controlled Medicine. On Tuesday, 5th September, the session ‘Herbals for health world- with symptomatic therapy. In these cases, the application of medicinal plants wide – WHO strategy and Herbal Regulation for Meeting People’s Need’ with anti-inflammatory, analgesic, antiseptic, antimicrobial, antidiarrheal or provided an excellent forum for all participants to discuss the needs for inter- immune-stimulatory activity may provide a valuable alternative widely ac- national educational, regulatory and research activities. cepted by animal owners. To assist veterinary practitioners in the fit-to-pur- We would like to take the opportunity to express our sincere thanks and pose use of medicinal plants, we launched a decision support system describ- appreciation to all participants of the conference, and to the sponsors and ing their organoleptic/pharmacologic properties and the applied preparations/ exhibitors. They all contributed significantly to make this meeting a success. doses in domestic animal species. The system also provides botanical charac- We also would like to thank the members of the organizing committee for all teristics of medicinal plants, their composition and safety profile, falsifications, the efforts during the preparation phase of the congress, and to our staff legal aspects for administrations to food-producing animals and, if applicable, members and students who volunteered to assist us in various organizational indications on their doping relevance. This decision support system can be “ ” tasks during the conference. accessed under www.phytoarznei.ch taking advantage of various user- Last, but not least, we would like to thank Thieme Publishers for their gener- friendly search functions. The underlying database is being expanded and ous support, and for publishing the conference abstracts in Planta Medica updated regularly. International Open. Prof. Dr. Matthias Hamburger & Prof. Dr. Veronika Butterweck On behalf of the Organizing Committee Planta Medica International Open 2017; 4: S1–S202 S1 Abstracts | GA 2017 Su-Veterinary Medicine Satellite Symposium-KNL-02 mising tools for the development of new treatment concepts for chronic Recent challenges in veterinary pharmacotherapy – disease of small animals. could medicinal plants be an option? Su-Veterinary Medicine Satellite Symposium-SL-01 1 Authors Fink-Gremmels J How to gather information from veterinary practise? Institute 1 Utrecht University, IRAS, Utrecht, Netherlands The “Idialoog System” for assessing the use of Guides DOI 10.1055/s-0037-1608013 with information on natural products The use of medicinal plants has a long tradition all over the world, both in human and animal health care. Recently, the challenge to overcome the global Authors Groot M1, Kissels W2, Feller R3 emergence of antimicrobial resistance, has initiated numerous research activ- Institute 1 RIKILT Wageningen University & Research, Wageningen, ities to understand the benefits (and limitations) of herbal remedies in the Netherlands; 2 Kissels Consulting, Bilthoven, Netherlands; 3 NewCurrent, treatment of infectious diseases, which can be discussed along the following Hilversum, Netherlands lines: DOI 10.1055/s-0037-1608015 1. In contrast to common antibiotics, which are generally single small Objective was to assess the use by veterinarians of the Guides for farmers to molecules, plants produce complex mixtures of related substances with keep their animals healthy with natural products. These booklets are published antimicrobial activity. These mixtures of active ingredients, impair bacterial by the Dutch government to help in reducing the use of antibiotics in livestock metabolism and replication at multiple sites and hence do not easily induce by veterinarians. A questionnaire according to the iDiaLo og methodology, was the expression of specific resistance genes. This has been very well distributed among all approved veterinarians that take part in a quality assur- documented for many essential oils, and their different chemical classes of ance program for a specific species. This Idialoog methodology is a proven active ingredients. research technique that allows for a high response and delivers relevant in- 2. In a clinical situation, bacterial infections are commonly associated with the formation on the primary question for the target group. Additional informa- formation of bacterial biofilms. Plants express various substances that tion on use of natural products and the role of the veterinarian was collected. interfere with biofilm formation, inhibiting the initial phase of quorum All responses (answers and opinions) are anonymised and grouped. The parti- sensing. By this activity, herbal remedies can significantly improve and cipants receive this as feedback via email (figure 1). Within iDiaLoog, all maintain the efficacy of common antibiotics in the treatment of acute and participants are equal and can participate at any time that suits them best. chronic infections. Because of its near-real-time feedback properties it is attractive for partici- 3. Most herbal extracts possess not only antibacterial activity, but also anti- pants to join and thus ensuring a high response rate. iDiaLoog is a simple, oxidant and anti-inflammatory properties, which contribute to an effective and efficient manner to gather and share relevant and actual infor- uneventful recovery from infections. mation about specific topics. This provides practitioners with insight of their In the light of these mechanisms-based evidence for their beneficial effects, peer group. traditional plant remedies should be re-considered in the treatment
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