Ana I. Cubillo
Curriculum Vitae
1. Personal Information Name: Ana Isabel Cubillo Fernandez Date of Birth: 22.08.1977 Nationality: Spanish/Swiss Marital Status: Married Children: Marc Ruben Hoesli, 12.10.2012 Valeria Alba Hoesli, 30.05.2016
Research Profiles: OrcID: 0000-0001-5657-7341 Google Scholar: https://scholar.google.ch/citations?user=ckkors4AAAAJ&hl=en ResearchGate: https://www.researchgate.net/profile/Ana_Cubillo2 Address: Office: Home: Child and Adolescent Psychiatry Dept (research) Johannisberstrasse 68 University Psychiatric Hospital (UPK) Basel CH-8645 Jona University of Basel Wilhelm-Klein-Strasse 27 CH- 4002 Basel Phone: +41 61 325 80 33 +41 78 948 36 58 Email: [email protected] [email protected]
2. Education 2009-2012 PhD in Child and Adolescent Psychiatry Institute of Psychiatry, Psychology and Neurosciences, King’s College London, UK Thesis: Effects of Atomoxetine and Methylphenidate on functional brain activation in medication-naïve children with Attention Deficit hyperactivity Disorder Supervisors: Prof. Katya Rubia, Dr Anna Smith 2003-2006 Certified Clinical Psychologist Spanish Ministry of Health (Ministerio de Salud y Consumo), Madrid, Spain (national examination) 2005-2007 Advanced Studies Diploma (DEA, equivalent to MPhil), Universidad Complutense de Madrid, Spain 2003-2005 MSc in Psychotherapy (specialization: Clinical and Psychoanalytic Psychotherapy), Universidad Pontificia de Comillas, Madrid, Spain 1995-2000 BSc in Psychology, Universidad Complutense de Madrid, Spain
3. Professional Experience 09/2019-present Senior Researcher (0.7 FTE) Department of Child and Adolescent Psychiatry(research) University Psychiatric Clinic/University of Basel, Switzerland 03/2020-present Senior Researcher (0.3 FTE) Department of Economics University of Zurich, Switzerland 09/2013–02/2020 Postdoctoral Researcher (average FTE: 0.8) Department of Economics University of Zurich, Switzerland 07/2012–09/2017 Visiting Researcher Department of Child and Adolescent Psychiatry Institute of Psychiatry, Psychology and Neuroscience King’s College, London, UK 01/2009–05/2012 PhD Fellowship
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Institute of Psychiatry, Psychology and Neuroscience King’s College London, UK 06/2010–05/2011 Consultant Psychologist (Child Psychology) Kids Company (charity organization that works with young ex-offenders and disadvantaged children through inner-city schools), London, UK 09/2007–09/2009 Alicia Koplowitz Fellow (Child Psychology and Psychiatry) Institute of Psychiatry Psychology and Neuroscience King’s College, London, UK 06/2006–09/2007 Specialist (Clinical Psychologist, Adult Substance Abuse) Private Practice. Madrid, Spain. 06/2006–09/2007 Specialist (Clinical Psychologist) Children’s Day Hospital, Pradera de San Isidro, Madrid, Spain 06/2003–05/2006 Clinical Psychologist trainee Hospital Universitario Doce de Octubre, Madrid, Spain
4. Institutional Responsibilities 04/2019 – 09/2019 Workgroup for the establishment of new guidelines at the different laboratories at the department, UZH 08/2014 – 06/2015 Organization of the Neuroeconomics seminar at the UZH 01/2015 Organization 3 days mini-course at the UZH on the neuroscience of empathy
5. Fellowships 01/2009-05/2012 PhD Studentship. National Institute for Health Research (NIHR) Biomedical Research Centre (BRC) for Mental Health at South London and Maudsley NHS Foundation Trust and Institute of Psychiatry, Psychology and Neurosciences, King’s College London Amount: £71,000
07/2007-09/2009 Alicia Koplowitz Fellow (Child Psychology and Psychiatry). Institute of Psychiatry at King’s College, London, UK. Amount: £60.000
6. Memberships in panel, boards, reviewing activities Ad-hoc reviewer European Neuropsychopharmacology; Journal of Neurodevelopmental Disorders; Human Brain Mapping; Journal of Psychiatric Research; Psychiatry Research Neuroimaging; Brain Structure and Function; Child and Adolescent Psychiatry and Mental Health; Neuroimage: Clinical, Developmental Cognitive Neuroscience; Journal of Psychopharmacology; Cognitive, Affective and Behavioural Neuroscience; American Journal of Psychiatry
Member of Member of the ADHD-ENIGMA consortium consortiums
7. Active Membership in Scientific Societies Since 2018 Swiss Society for Neuroscience (SSN) Since 2018 Society for Neuroscience (SfN) Since 2018 Flux Society, the Society for Developmental Cognitive Neuroscience Since 2018 Society for Neuroeconomics Since 2010 Colegio Oficial de Psicologos de Madrid, Clinical Psychologist
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8. Prizes and Awards 07/2019 Conference Travel Award. Swiss Academy of Humanities and Social Sciences (Schweizerische Akademie der Geistes- und Sozialwissenschaften, SAGW) for the 7th Flux Conference (Developmental Cognitive Neuroscience), New York, United States of America, August 2019. 06/2017 Conference Travel Award. Swiss Academy of Humanities and Social Sciences (Schweizerische Akademie der Geistes- und Sozialwissenschaften, SAGW) for the 18th European Conference on Developmental Psychology, Utrecht, Netherlands, August 2017. 09/2011 Young Scientist Symposium Award. 24th European College of Neuropsychopharmacology (ECNP) Congress, Paris, France (included 2- year membership to European College of Neuropsychopharmacology, ECNP, from 2011-2013) 03/2011 Best Poster Award. European College of Neuropsychopharmacology (ECNP) workshop, Nice, France 06/2009 Pan-American Association Editors’ Award, oral communication category. Meeting of the Spanish Association of Child and Adolescent Psychiatry, Pamplona, Spain (one of three “best talk” awardees) 06/2009 Pan-American Association Editors’ Award, poster category. Meeting of the Spanish Association of Child and Adolescent Psychiatry, Pamplona, Spain (one of three “best poster” awardees) 05/2009 Young Scientist Award. 2nd International Congress on ADHD 2009, Vienna, Austria
9. Oral presentations at Conferences 2020 Intra-individual variability in task performance after cognitive training is associated with long-term outcomes in children. Presented at the online conference of the Mathematical Cognition and Learning Society (online). Symposium title: Explaining the relationship between working memory resp. related cognitive skills and mathematical learning. Chair: Dr Viesel- Nordmeyer. Available at https://www.youtube.com/hashtag/mclsonline. 2020 Shared normalisation of sustained attention-related brain dysfunctions of stimulants and non-stimulant medications in ADHD. Presented at the 75th Society of Biological Psychiatry Symposium (online). Symposium title: “Rewiring the “restless brain”: variability and translational neuroimaging in Attention-Deficit/Hyperactivity Disorder (ADHD)”. Chair: Prof Castellanos. Available at https://www.youtube.com/watch?v=fdmhycAvJvo. 2020 The impact of developmental trajectories of peer victimization on the neurobiology of social decision-making. Presented at the 2nd International Seminar of The Zurich Project on the Social Development from Childhood to Adulthood (z-proso), Cordoba (Spain), Feb 2020 2019 Response time variability is associated with more current and future negative life outcomes in children. Paper presented at the 7th FLUX conference (Developmental Cognitive Neuroscience), New York, United States. 2018 Insights into the neural and behavioural impacts of WM training in school- aged children. Paper presented at the 16th Annual Meeting of the Society for NeuroEconomics, Philadelphia, United States. 2018 Neural impact of monetary incentives on cognitive control. Paper presented at the Annual Research Forum, Swiss Center for Affective Sciences, Geneva, Switzerland. 2017 Neural and behavioural impact of WM and self-regulation training in school-aged children. Paper presented at the 18th European Conference on Developmental Psychology (ECDP), Utrecht, the Netherlands.
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2013 Persistence of brain deficits in adult ADHD. Paper presented at the 26th European College of Neuropsychopharmacology (ECNP) Congress, Barcelona, Spain. 2012 Shared and task-specific effects of methylphenidate and atomoxetine on brain function in children with ADHD. Paper presented at the 2nd International ADHD Conference, Barcelona, Spain. 2011 Fronto-striatal brain dysfunction in adults with childhood ADHD and persistent hyperactive/inattentive behaviours during sustained attention and reward. Paper presented at the 22nd Meeting of Eunethydis (European Network on Hyperkinetic Disorders), Budapest, Hungary. 2011 Differential effects of methylphenidate and atomoxetine on brain activation in medication-naïve children with ADHD. Paper presented at the 24th European College of Neuropsychopharmacology (ECNP) Congress, Paris, France. 2009 Fronto-striatal brain dysfunction in adults with childhood ADHD and persistent hyperactive/inattentive behaviours followed from childhood during interference inhibition and attention allocation. Paper presented at the 2nd International Congress on ADHD, Vienna, Austria.
10. Teaching Fall semester 2020 Cognitive Neuroscience Course Fall semester 2019 Lectures on Attention and Cognitive Control. University of Zurich Since 09/2019 Regular collaboration at the AG Stadler Master colloquium Seminar Series University (15 students; since Fall semester 2019) Scientific input, discussion, Psychiatric Clinic feedback; teaching of science skills Basel 2012-2019 Online MSc Clinical Neuropsychology. Faculty member. University Pablo Post-graduate degrees center. Olavide, Spain 2012 Online MSc Child and Adolescent Neuropsychology. Faculty member. University Pablo Post-graduate degrees center. Olavide, Spain
11. Supervision of Junior Researchers Since 09/2020 Project: “Investigating the specificity of neural correlates for emotion University processing deficits in conduct disorder and autism spectrum disorders”. Psychiatric Clinic Supervision PhD student on participants recruitment, paradigms Basel development, data collection, analysis, thesis writing and general dissemination Antonia Tkalcec Since 09/2020 Project: “Linking traumatic experiences, self-regulation and aggression in University adolescents with and without conduct disorder” Psychiatric Clinic Supervision of Master student in data analysis and thesis writing Basel Agnes Detert, Sarah Trefzer Since 09/2020 Project: “Investigating the specificity of neural correlates for emotion University processing deficits in conduct disorder and autism spectrum disorders”. Psychiatric Clinic Supervision of Master student in data analysis and thesis writing Basel Lorena Leuenberger 02/2020-08/2020 Project: “Strategic social decision making: The influence of emotion processing on value- based choices in a repeated interaction paradigm”
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University of Supervision of Master student in data analysis and thesis writing Zurich Lisa Grossenbacher 02/2019-08/2019 Project: “Estimating the Influence of Age in Risk Taking with a Hierarchical University of Drift-Diffusion Model” Zurich Supervision of Master student in data analysis and thesis writing Harun Hrncic 05/2019-01/2019 Project: “Decision-making: A comparison of intertemporal and social University of preferences” Zurich Supervision of Master student in data analysis and thesis writing Hanae Rodriguez Prieto
12. Career Breaks 10/2012-09/2013 Maternal leave (Marc, 12.10.2012) 05/2016-01/2017 Maternal leave (Valeria, 30.05.2016)
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Ana Isabel Cubillo Fernandez Publication List
1. Cubillo A, Hermes H, Berger E, Winkel K, Schunk D, Fehr E, Hare TA (2020). Intra-individual variability in task performance after cognitive training is associated with long-term outcomes in children. BioRxiv, doi: https://doi.org/10.1101/2020.11.19.390427 2. Cubillo A, Makwana AB, Hare TA (2019). Differential modulation of cognitive control networks by monetary reward and punishment. Social, cognitive and affective neuroscience. 3(5):305-317. doi: 10.1093/scan/nsz006. 3. Kowalcyk O*, Cubillo A*, Smith A, Barrett N, Giampietro V, Brammer M, Simmons A, Rubia K (2019). Methylphenidate and atomoxetine normalise fronto-parietal underactivation during sustained attention in ADHD adolescents. European Neuropsychopharmacology 29 (10), 1102- 1116. https://doi.org/10.1016/j.euroneuro.2019.07.139 (*shared first authorship) 4. Norman LJ, Carlisi CO, Christakou A, Cubillo A, Murphy CM, Chantiluke K, Simmons A, Giampietro V, Brammer M, Mataix- Cols D, Rubia K (2017). Shared and disorder-specific task- positive and default mode network dysfunctions during sustained attention in paediatric Attention-Deficit/Hyperactivity Disorder and obsessive/ compulsive disorder. Neuroimage: Clinical (5):181-193. doi: 10.1016/j.nicl.2017.04.013 5. Boedhoe, P. S., Van Rooij, D., Hoogman, M., Twisk, J. W., Schmaal, L., Abe, Y., ... Cubillo A, …& Arango, C. (2020). Subcortical brain volume, regional cortical thickness, and cortical surface area across disorders: findings from the ENIGMA ADHD, ASD, and OCD working groups. American Journal of Psychiatry, 177(9), 834-843. Doi: 10.1176/appi.ajp.2020.19030331 6. Kong, X. Z., ENIGMA Laterality Working Group, Francks, C., Kong, X. Z., Mathias, S. R., Guadalupe, T., ... Cubillo A, … & Alhusaini, S. (2020). Reproducibility in the absence of selective reporting: An illustration from large‐scale brain asymmetry research. Human Brain Mapping. https://doi.org/10.1002/hbm.25154 7. Patel, Y., Parker, N., Shin, J., Howard, D., French, L., Thomopoulos, S. I., ... Cubillo A, … & Alda, M. (2020). Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders. Jama Psychiatry. doi:10.1001/jamapsychiatry.2020.2694 8. Hoogman, M., Muetzel, R., Guimaraes, J. P., Shumskaya, E., Mennes, M., Zwiers, M. P., ... Cubillo A, … & Soliva Vila, J. C. (2019). Brain imaging of the cortex in ADHD: a coordinated analysis of large-scale clinical and population-based samples. American Journal of Psychiatry, 176(7), 531-542. doi: 10.1176/appi.ajp.2019.18091033. 9. Hoogman, M., Bralten, J., Hibar, D. P., Mennes, M., Zwiers, M. P., Schweren, L. S., ...Cubillo A, … & de Zeeuw, P. (2017). Subcortical brain volume differences in participants with attention deficit hyperactivity disorder in children and adults: a cross-sectional mega- analysis. The Lancet Psychiatry, 4(4), 310-319. doi: 10.1016/S2215-0366(17)30049-4. 10. Lim L, Chantiluke K, Cubillo A, Smith AB, Simmonds A, Mehta MA, Rubia K (2015). Disorder- specific grey matter deficits in attention deficit hyperactivity disorder relative to autism spectrum disorder. Psychol Med. 45(5):965–976. doi:10.1017/S0033291714001974. 11. Cubillo A*, Smith A*, Barrett N, Giampietro V, Brammer M, Simmons A, Rubia K (2014). Drug-specific frontal laterality effects of atomoxetine and methylphenidate in ADHD boys during working memory. Psychol Med. 44(3):633–646. doi:10.1017/S0033291713000676 (*shared first authorship) 12. Cubillo A*, Smith AB*, Barrett N, Giampietro V, Brammer MJ, Simmons A, Rubia K (2014). Shared and drug-specific effects of atomoxetine and methylphenidate on inhibitory brain dysfunction in medication-naive ADHD boys. Cerebral Cortex 24(1): 174–185. doi:10.1093/cercor/bhs296. (*shared first authorship) 13. Hart H, Chantiluke K, Cubillo AI, Smith AB, Simmons A, Brammer MJ, Marquand AF, Rubia K (2014). Pattern classification of response inhibition in ADHD: toward the development of neurobiological markers for ADHD. Human Brain Mapping 35(7):3083–3094. doi:10.1002/hbm.22386.
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14. Hart H, Marquand AF, Smith A, Cubillo A, Simmons A, Brammer M, Rubia K (2014). Predictive neurofunctional markers of attention deficit/hyperactivity disorder based on pattern classification of temporal processing. J Am Acad Child Adol Psych 53(5):569–578.e1. doi:10.1016/j.jaac.2013.12.024. 15. Rubia K, Alzamora A, Cubillo A, Smith AB, Radua J, Brammer, MJ (2014). Effects of stimulants on brain function in ADHD: a systematic review and meta-analysis. Biol Psychiatry 76(8):616–628. doi:10.1016/j.biopsych.2013.10.016. 16. OHarney, A. D., Marquand, A., Rubia, K., Chantiluke, K., Smith, A., Cubillo, A., ... & Filippone, M. (2014, August). Pseudo-marginal Bayesian multiple-class multiple-kernel learning for neuroimaging data. In 2014 22nd International Conference on Pattern Recognition (pp. 3185-3190). IEEE. DOI: 10.1109/ICPR.2014.549 17. Christakou A, Murphy C, Chantiluke K, Cubillo A, Smith A, Murphy D, AIMS Consortium, Rubia K (2013). Disorder-specific functional abnormalities during sustained attention in youth with attention deficit hyperactivity disorder (ADHD) and with autism. Molecular Psychiatry 18(2):236–244. doi:10.1038/mp.2011.185. 18. Lim L, Marquand A, Cubillo A, Smith AB, Chantiluke K, Simmons A, Mehta M, Rubia K (2013). Disorder-specific predictive classification of adolescents with attention deficit hyperactivity disorder (ADHD) relative to autism using structural magnetic resonance imaging. PLOSone 8(5): e63660. doi: 10.1371/journal.pone.0063660. 19. Smith A*, Cubillo A*, Barrett N, Giampietro V, Simmons A, Brammer M, Rubia K (2013). Differential neurofunctional effects of methylphenidate and atomoxetine in boys with attention deficit hyperactivity disorder during time perception. Biol Psych 74(8):615–622. doi:10.1016/j.biopsych.2013.03.030 (*shared first authorship) 20. Cubillo A, Halari R, Smith A, Giampietro V, Taylor E, Rubia K (2012). A review of fronto- striatal and fronto-cortical brain abnormalities in children and adults with attention deficit hyperactivity disorder (ADHD) and new evidence for dysfunction in adults with ADHD during motivation and attention. Cortex 48:194–215. doi:10.1016/j.cortex.2011.04.007 21. Cubillo A, Halari R, Taylor E, Giampietro V, Rubia K. (2011). Fronto-striatal underactivation during interference inhibition and attention allocation in grown up children with attention deficity/hyperactivity disorder and persistent symptoms. Psychiatry Research: Neuroimaging, 193(1):17–27. doi:10.1016/j.pscychresns.2010.12.014 22. Rubia K, Halari R, Cubillo A, Mohammad AM, Brammer M, Taylor E (2011). Methylphenidate normalises fronto-striatal underactivation during interference inhibition in medication-naive children with attention-deficit hyperactivity disorder. Neuropsychopharmacology 36(8):1575– 1586. doi:10.1038/npp.2011.30 23. Cubillo A, Halari R, Ecker C, Giampietro V, Taylor E, Rubia K (2010). Reduced activation and inter-regional functional connectivity of fronto-striatal networks in adults with childhood attention deficit hyperactivity disorder (ADHD) and persisting symptoms during tasks of motor inhibition and cognitive switching. J Psychiatr Res. 44:629–639. doi:10.1016/j.jpsychires.2009.11.016. 24. Cubillo A, Rubia K (2010). Structural and functional brain imaging in adult attention deficit hyperactivity disorder (ADHD): a review. Expert Rev Neurother. 10(4):603–620. doi:10.1586/ern.10.4. 25. Rubia K, Cubillo A, Smith A, Woolley J, Heyman I, Brammer MJ (2010). Disorder-specific dysfunction in right inferior prefrontal cortex during two inhibitory control tasks in children with attention deficit/hyperactivity disorder (ADHD) compared to children with obsessive- compulsive disorder (OCD). Human Brain Mapping 31(2):287–299. doi:10.1002/hbm.20864. 26. Rubia K, Halari R, Cubillo A, Mohammad A, Scott S, Brammer M (2010). Disorder-specific inferior frontal dysfunction in boys with pure attention deficit/hyperactivity disorder compared
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to boys with pure CD during cognitive flexibility. Human Brain Mapping 31(12):1823–1833. doi:10.1176/appi.ajp.2008.08020212
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