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Van Andel Institute Is an Independent Nonprofit Biomedical Research and Science Education Organization Committed to Improving Th Van Andel Institute is an independent nonprofit biomedical research and science education organization committed to improving the health and enhancing the lives of current and future generations. TABLE OF CONTENTS 2 Fact Sheet 3 By the Numbers 4 Leadership Biographies 6 Center for Epigenetics 7 Center for Neurodegenerative Science 8 Center for Cancer and Cell Biology 9 Core Technologies and Services 10 Van Andel Institute Graduate School 11 Van Andel Education Institute 12 Frequently Asked Questions 1 Fact Sheet By the Numbers WHAT WE STUDY WHERE WE COLLABORATE Neurofibromatosis type 1 Breast cancer Osteoporosis Blood cancer Depression Structural biology Parkinson’s disease Bone cancers Asthma Prion disease EPIGENETICS Pancreatic cancer Aging Ovarian Cancer Cancer Sarcoma Heart disease Osteoarthritis Diabetes Prostate cancer Colorectal cancer A DEDICATED TEAM VAN ANDEL INSTITUTE GRADUATE SCHOOL, Van Andel Institute has more than FOSTERING TOMORROW’S LEADERS 364 employees, with 234 of them working in research and graduate education. 33 VAIGS faculty members Through biomedical FOUNDED: 1996 by Jay and Betty Van Andel 5.4 year average time to Ph.D. LOCATION: Grand Rapids, Michigan research and science MISSION STATEMENT: Through biomedical research and science 3 seven-week laboratory rotations education, education, Van Andel Institute is committed to improving the health during the first two semesters and enhancing the lives of current and future generations. Van Andel Institute is VARI VAEI VAI WHO ARE WE? years of doctoral candidate thesis committed to Van Andel Institute is an agile biomedical research and science 3 education institute known for breaking down barriers that hold innovation research in a faculty mentor’s lab improving the health captive. Van Andel Research Institute (VARI) is a world leader in cancer and enhancing the epigenetics and Parkinson’s disease research. Collaborating with academia, industry and philanthropy, the Institute orchestrates VAN ANDEL RESEARCH INSTITUTE SCIENTIFIC IMPACT lives of current and cutting-edge clinical trials to improve human health. VAEI has worked with more than future generations. Van Andel Education Institute (VAEI) is leading a national 36 principal investigators revolution in science education by uniquely empowering teachers to engage students to think and act like scientists. cores 3,800 students Van Andel Institute Graduate School (VAIGS) develops future 8 leaders in biomedical research through an intense problem-focused and Ph.D. degree in cell and molecular genetics. 3 fellows of the American Association 3,100 teachers Purple Community is Van Andel Institute’s grassroots community for Cancer Research Academy since 1996. awareness and fundraising program that connects individuals, schools, teams and companies who want to join the fight against cancer and neurodegenerative diseases to the resources needed for action. 3 fellows of the American Association for the Advancement of Science 3 members of the National Academy of Sciences *All numbers current as of October 2017 2 | VAN ANDEL INSTITUTE 3 Leadership Biographies VAN ANDEL RESEARCH INSTITUTE In addition to managing his laboratory at Van Andel Research Institute and serving as director of the Institute’s Center for Neurodegenerative Science, he is the co-editor-in-chief of the Peter Jones, Ph.D., D.Sc. Journal of Parkinson’s Disease and chair of the Linked Clinical Chief Scientific Officer; Director, Trials committee, which aims to repurpose already approved Center for Epigenetics drugs to treat Parkinson’s. Brundin also has coordinated multiple international research programs. David Van Andel Dr. Peter Jones is a pioneer in the field of epigenetics, particularly Chairman and its role in cancer. His laboratory Chief Executive Officer discovered the effects of the epigenetic drug 5-azacytidine on Bart Williams, Ph.D. David Van Andel is Chairman and CEO of Van Andel Institute in Grand cytosine methylation and he first established the link between Director, Center for Cancer Rapids, Michigan. He is also an entrepreneur involved in several other DNA methylation, gene expression and cell differentiation. His and Cell Biology work has led to the development of novel cancer therapies business interests in the natural and life science products industries. that target the epigenome. His current research continues Dr. Bart Williams is an internationally these efforts with a focus on finding additional new treatments recognized expert in bone biology, The son of Jay Van Andel, founder of Van Andel Institute and co-founder to better combat, or even prevent, cancer. specifically in the area of Wnt signaling of Amway Corporation, he is currently a member of Amway’s Board of in health and disease states. His Directors and serves on its Executive, Governance and Audit committees. Jones joined the University of Southern California (USC) in laboratory at Van Andel Research 1977, after earning a Ph.D. from the University of London. Prior to leading Van Andel Institute, he had been in various positions Institute studies the role of the Wnt pathway in normal bone He served as director of the USC Norris Comprehensive Cancer development and in cancers that commonly spread to the bone (such at Amway since 1977, including chief operating officer of Amway’s Pyxis Center between 1993 and 2011. In 2013, he was appointed to his as prostate, breast and lung cancers). He is also an expert in the Innovations Business Unit, and was senior vice president–Americas and current position as chief scientific officer of Van Andel Research development of preclinical models of skeletal disease and cancer. Europe, overseeing Amway business activities in North America and in Institute (VARI) in Grand Rapids, Michigan, where he also leads a lab and serves as director of the Institute’s Center for Epigenetics. Williams received his Ph.D. in biology from Massachusetts Institute 22 European and 11 Latin American affiliates. Jones is a past president of the American Association for Cancer of Technology in 1996 where he trained with Tyler Jacks. For Research (AACR), a Fellow of the AACR Academy, a Fellow of the three years, he was a postdoctoral fellow at the National Institutes American Association for the Advancement of Science and was of Health (NIH) in the laboratory of Harold Varmus, former director elected to the National Academy of Sciences. He has published of NIH. Williams joined Van Andel Research Institute as a scientific more than 300 scientific papers and received several honors, investigator in July 1999. He is now a professor and the director including the Outstanding Investigator Grant from the National of the Institute’s Center for Cancer and Cell Biology. He has served Cancer Institute. He and his colleague Dr. Stephen Baylin on more than two dozen NIH study sections and also serves on VAN ANDEL EDUCATION INSTITUTE shared the Kirk A. Landon Award for Basic Cancer Research from numerous additional grant and conference review committees. the AACR in 2009 and the Medal of Honor from the American He is currently an editorial board member for several journals, Cancer Society in 2011. He and Baylin led the first Stand Up To including the Journal of Biological Chemistry, Journal of Clinical Cancer (SU2C) Epigenetics Dream Team and currently lead the Investigation, Bone Research and PLoS One. Terra Tarango VAN ANDEL INSTITUTE GRADUATE SCHOOL VARI–SU2C Epigenetics Dream Team. Van Andel Education Institute Director and Education Officer Terra Tarango is an accomplished Steven J. Triezenberg, Ph.D. Scott Jewell, Ph.D. executive in the education industry Dean, Van Andel Institute Patrik Brundin, M.D., Ph.D. Director, Core Technologies with more than 15 years of experience Graduate School; Professor, in educational publishing and services. Associate Director of and Services Center for Epigenetics, Research; Director, Center for Prior to joining Van Andel Institute, Van Andel Research Institute Tarango served as president of SDE, one of the largest providers Neurodegenerative Science Dr. Scott Jewell earned his master’s of professional development for pre-K through 12th grade degree and Ph.D. in experimental educators in the U.S. Before that, she developed award-winning Dr. Steven J. Triezenberg received Dr. Patrik Brundin is one of the pathology and immunology from print and digital curriculum with Houghton Mifflin Harcourt, the his bachelor’s degree in biology and top cited researchers in the field The Ohio State University. He largest educational publisher in the nation. She is an expert in education from Calvin College in Grand Rapids, Michigan. His Ph.D. of neuroscience with more than served at Ohio State as director for instructional climate and culture and has devoted her career to training in cell and molecular biology at the University of Michigan 300 publications on Parkinson’s the Human Tissue Resource Network and as associate director increasing curiosity, creativity and critical thinking in the classroom. was followed by postdoctoral research at the Carnegie Institution of disease and related topics. He has 35 years of experience of the OSU Comprehensive Cancer Center’s Biorepository and Washington. Before joining Van Andel Institute in 2006, Triezenberg studying neurodegenerative diseases, Parkinson’s disease Biospecimen Resource, where his dedicated, creative efforts led As Van Andel Education Institute’s (VAEI) director and education was a faculty member of the Department of Biochemistry and pathogenesis and therapeutic neural transplantation
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