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Subtypes Type Class cst-science.com/humanmarkers For pathwaykeyand background,pleasevisit: For Research Use Only. Not For Use In Diagnostic Procedures. 18-IMM-18284-FLY1-E1 Mk APPLICATIONS &REACTIVITYKEY: Granulocytes monkey / C chicken / CD63 Tryptase CD117 FcεR1α Mast cells CD117 FcεR1α Basophils CD16 Siglec-8 CD193 Eosinophils CD15/SSEA1 CD66b CD16 Neutrophils CD203c Activated CD203c Activated Supressor Cells Mi mink / Myeloid-Derived + + – and and + + + – + + or and and + + + and and + and Dm + D. melanogaster/ WB Western Blotting/ ( MDSC s)

HLA-DR HLA-DR CD14 CD15 (PMN) MDSCs Polymorphonuclear CD14 CD15 (M) MDSCs Monocytic X for IHC(Human) Tumor-Infiltrating ImmuneCell MarkerGuide Dendritic Cells Xenopus Plasmacytoid – + + – and and and and IP – –

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/ Z Myeloid Cells zebrafish / CD317 Siglec-H Activated CD83 + + B + bovine / and IHC CD11b Dendritic Cells Conventional / Activated Dg CD83 + dog / Tumor-Infiltrating Immune Cell Marker Guide (Human) Guide Marker Cell Immune Tumor-Infiltrating + Pg HLA-DR CD11c pig / Sc CD141 CLEC9A XCR1 CLEC9A CD141 presentation) (excel atcross- DCs CD141 XCR1 CLEC9A CD141 CD1c DCs CD1c CD1c DCs CD1c CLEC9A + and + S. cerevisiae IF / Macrophages Macrophages + + – – + – and and + – + – or or or + or – + – or or

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+ Functional StateMarkers positive negative rat / + + – Plasma Cells Hm / / high expression hamster low expression rev. 11/20/18 BCMA CD138 + + or cst-science.com/humanmarkers For pathwaykeyand background,pleasevisit: For Research Use Only. Not For Use In Diagnostic Procedures. 18-IMM-18284-FLY1-E1 Mk APPLICATIONS &REACTIVITYKEY: © 2019CellSignalingTechnology, Inc.CellSignalingTechnology, CST, andXParetrademarksofCellSignalingTechnology, Inc. U.S.PatentNo.5,675,063.Allothertrademarksarethepropertyoftheirrespectiveowners. #24326 #75181 #45581 #85336 #85061 #93668 #88183 #45208 #13232 #43248 #86163 #15372 #37805 #49420 #46890 #96098 #98377 #91992 #93498 #91882 #76437 #55051 #55618 #13917 #37259 #90176 #3576 #5852 #3570 monkey / (IHC Specific) FoxP3 (D2W8E™)RabbitmAb CD206/MRC1 (E2L9N)RabbitmAb CD163 (D6U1J)RabbitmAb CD86 (E2G8P)RabbitmAb CD68 (D4B9C)XP CD63 (D4I1X)RabbitmAb(IHCSpecific) (IHC Specific) CD45RO (UCHL1)MousemAb CD45 (D9M8I)XP CD44 (156-3C11)MousemAb CD44 (E7K2Y)XP CD19 (D4V4B)XP CD16 (D1N9L)RabbitmAb (IHC Formulated) CD14 (D7A2T)RabbitmAb CD11c (D3V1E)XP CD8α (D8A8Y)RabbitmAb CD3ε (D7A6E™)XP Arginase-1 (D4E3M™)XP TNFRSF17/BCMA (E6D7B)RabbitmAb TIM-3 (D5D5R™)XP T-bet/TBX21 (D6N8B)XP PD-1 (EH33)MousemAb(IHC-Specific) PD-1 (D4W2J)XP NCAM (CD56)(123C3)MousemAb LAG3 (D2G4O™)XP c-Kit (D3W6Y)XP ITGAM/CD11B (D6X1N)RabbitmAb Granzyme B(D6E9W)RabbitmAb GATA-3 (E2N1Y)MousemAb GATA-3 (D13C9)XP C chicken / Mi

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Key Products forHuman Tumor-Infiltrating ImmuneCell Markers forIHC Visit X Xenopus WB, IP, IHC-P, F WB, IP, IHC-P, F ChIP-seq WB, IP, IHC-P, IF-IC,F, ChIP, IHC-P WB, IP, IHC-P, F WB, IHC-P, IF-IC,F WB, IHC-P WB, IP, IHC-P WB, IHC-P WB, IHC-P WB, IHC-P, IF-IC,F WB, IHC-P, IF-IC,F, ChIP IHC-P WB, IHC-P WB, IHC-P WB, IHC-P, IF-IC IHC-P, IF-IC,F IHC-P IHC-P IP,WB, IHC-P, IF-IC,F WB, IP, IHC-P, IF-IC,F WB IHC-P WB, IP, IHC-P IHC-P IHC-P WB, IHC-P IP,WB, IHC-P, F IP,WB, IHC-P WB, IHC-P, IF, F APPLICATIONS www.cellsignal.com IP Immunoprecipitation / / Z zebrafish / B bovine / IHC forfulllistingofantibodies,related kits,andreagents. Immunohistochemistry / H H, M H H, M,(Mk) H H H H H H H H H H, M,R H, M,(B) H H H H H H, M,R REACTIVITY H H H H H H H H Dg dog / Pg pig / Sc S. cerevisiae IF Immunofluorescence / / All the Leica cell lungcarcinoma on using#93498performed analysis ofparaffin-embedded humannon-small CD163 (D6U1J)Rabbit mAb#93498: performed ontheLeicaperformed human colonadenocarcinoma using#93668 #93668: Arginase-1 (D4E3M™)XP all speciesexpected/ F ® IHC analysisofparaffin-embedded Flow Cytometry/ Bond™Rx. ( ) ® BOND™Rx. 100% sequencehomology ChIP ® Rabbit mAb Chromatin Immunoprecipitation/ IHC IHC carcinoma using#86163. IHC analysisofparaffin-embedded humancolon PD-1 (D4W2J)XP carcinoma using#85061. IHC analysisofparaffin-embedded human breast CD3ε (D7A6E™)XP -IC Immunocytochemistry / ® Rabbit mAb#86163: ® Rabbit mAb#85061: -P Paraffin / -F Frozen / E-P Peptide ELISA/ alveolar macrophages. carcinoma stainingof using#45208.Note IHC analysisofparaffin-embedded humanlung TIM-3 (D5D5R™)XP Leica adenocarcinoma onthe using#91882performed analysis ofparaffin-embedded humanlung CD86 (E2G8P)Rabbit mAb#91882: ® BOND™Rx. H human / ® M Rabbit mAb#45208: mouse / R rat / Hm IHC IHC hamster