Cultured Meat Factories of the Future

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Cultured Meat Factories of the Future FEBRUARY 2021 FEBRUARY PIONEERING MEAT 2.0 We are developing the sustainable cultured meat factories of the future. These B2B factories target multi- species cell-based agriculture and 3D bioprinting to produce a range of cultured meat products, including steak. © 2021 ALL RIGHTS RESERVED WWW.MEATECH3D.COM 2 DISCLAIMERS This presentation was prepared Meat-Tech 3D Ltd. ("MeaTech" or reports filed in connection with the Company with the Israel the “Company”), and is given to you only for the provision of concise Securities Authority and the Tel Aviv Stock Exchange Ltd., including information for the sake of convenience, and may not be copied or warnings regarding forward-looking information, as defined in distributed to any other person. The data and information included the Securities Law, 5728-1968, included therein. The forward- in this presentation should not be interpreted as advice and should looking information in the presentation may not materialize, in not be relied on for any purpose. Such data and information should whole or in part, or may materialize differently than expected, or not be copied or used except as expressly permitted in writing. This may be affected by factors that cannot be assessed in advance. presentation does not purport to be comprehensive or to contain For the avoidance of doubt, it is clarified that the Company do not any and all information which might be relevant in connection undertake to update and/or modify the information included in with the making of a decision on an investment in securities of the presentation to reflect events and/or circumstances occurring the Company. No explicit or implicit representation or undertaking after the date of preparation of the presentation. This presentation is given by any person regarding the accuracy or integrity of is not an offer or invitation to buy or subscribe for any securities. any information included in this presentation. In particular, no This presentation and anything contained herein are not a basis for representation or undertaking is given regarding the realization or any contract or undertaking, and are not to be relied upon in such reasonableness of any forecasts regarding the future chances of the context. The information provided in the presentation is not a basis Company. To obtain a full picture of the activities of the Company for the making of any investment decision, nor a recommendation or and the risks entailed thereby, see the full immediate and periodic an opinion, nor a substitute for the discretion of a potential investor. © 2021 ALL RIGHTS RESERVED WWW.MEATECH3D.COM 3 CONVENTIONAL - MEAT 1.0 RESOURCE-INTENSIVE INPUTS AND COSTLY ENVIRONMENTAL OUTPUTS LAND & FEED EMISSIONS 33% of croplands 18% of atmospheric dedicated for greenhouse gases, animal feed in addition to effluent and runoff INPUTS OUTPUTS OUTPUTS WATER RESOURCES MEAT PRODUCTS LIVESTOCK 8% of global In 2018, approximately freshwater supply 72 billion animals were dedicated to raising slaughtered Source: Food and Agriculture Organization of the United Nations ; Our World in Data © 2021 ALL RIGHTS RESERVED WWW.MEATECH3D.COM 4 CELLULAR AGRICULTURE - MEAT 2.0 RADICALLY MORE SUSTAINABLE: SLAUGHTER-FREE AND REDUCED EMISSIONS STEM CELLS & MUSCLE CELLS CELL MEDIA Efficient use of Stem cells are cell media differentiated into muscle cells INPUTS OUTPUTS OUTPUTS CLEAN ENERGY FAT CELLS FAT CELLS BIOREACTORS Stem cells are differentiated into fat cells © 2021 ALL RIGHTS RESERVED WWW.MEATECH3D.COM 5 EXPECTED POSITIVE IMPACT ON SUSTAINABILITY CONVENTIONAL FARMING COMPARED TO CULTURED MEAT PRODUCTION WATER USE CO2 EMISSIONS LAND USE CONVENTIONAL 2 MEAT (1KG) 16,000 LITERS 14 KG 160 M CULTURED 2,500 LITERS 3 KG 1.6 M2 MEAT (1KG) Source: CB Insights, Water Footprint Network, Business Insider, Forbes, Expert Interviews. © 2021 ALL RIGHTS RESERVED WWW.MEATECH3D.COM 6 The above illustration depicts our current expectations for the development our technologies and processes. SUSTAINABILITY: Cleaner, more recyclable inputs MEAT 2.0 SUPPLY CHAIN: Shortened and simplified POTENTIAL ADVANTAGES FOOD SECURITY: Exponential and just-in-time production FOR THE MEAT INDUSTRY 2.0 PRODUCTS: New ingredients and product categories © 2021 ALL RIGHTS RESERVED WWW.MEATECH3D.COM CAGR: % FORECAST MEAT CULTURED % SEGMENT PROTEIN ALTERNATIVE GROWING THE FASTEST % Source: A.T. Kearney analysis analysis Kearney A.T. % % PLANT BASED PLANT % % % % 7 © 2021 ALL RIGHTS RESERVED WWW.MEATECH3D.COM 8 CURRENT MEAT ALTERNATIVES LANDSCAPE PRODUCTS AND COMPETITORS ORGANOLEPTIC PROPERTIES + + + Nestle Cubiq Foods Mosa Meat Morning Star Peace Of Meat Memphis Meats Beyond Meat Eat Just Inc. Aleph Farms Impossible Foods FutureMeat Kellogg's SuperMeat TIME TO MARKET TODAY EMERGING NASCENT © 2021 ALL RIGHTS RESERVED WWW.MEATECH3D.COM 9 CULTURED MEAT PRODUCTION COSTS EXPECTED TO FALL CELL CULTURE MEDIA IS THE KEY COST DRIVER FOR CELLULAR AGRICULTURE Cell culture media is the nutritional liquid cells require to grow and proliferate. The price of cell media is projected to fall dramatically over the coming years. This opens the route to cost parity with traditional meat production. Source: The Good Food Institute © 2021 ALL RIGHTS RESERVED WWW.MEATECH3D.COM 10 REGULATORY PROGRESS - CULTURED MEAT REGULATORS AROUND THE WORLD APPEAR TO BE TAKING A POSITIVE STANCE TOWARDS CULTURED MEAT CHINA Positive announcements USA EU An initial formal agreement Requires ‘novel food’ and between the USDA and FDA food safety applications to oversee the production and labeling of cultured meat SINGAPORE Already approved cultured meat for sale in restaurants Source: Sources: Congressional Research Service; Regulation (EU); Food Navigator Asia; Singapore Food Agency © 2021 ALL RIGHTS RESERVED WWW.MEATECH3D.COM 11 MEATECH'SMEATECH'S B2B TECHNOLOGY PRODUCTION PROCESS © 2021 ALL RIGHTS RESERVED WWW.MEATECH3D.COM 12 FACTORY OF THE FUTURE A VISION OF A MULTI-SPECIES, MULTI-PRODUCT, HIGH-VOLUME CULTURED MEAT PRODUCTION PLANT The above illustration depicts our current expectations for the development our technologies and processes. © 2021 ALL RIGHTS RESERVED WWW.MEATECH3D.COM 13 MEATECH’S CORE R&D SCALING UP CELL-BASED PROTEIN PLANNED BIOREACTOR SYSTEMS & PROCESSES Multi-species biomass production technologies: • Fat • Muscle DEVELOPING HIGH THROUGHPUT 3D TISSUE ENGINEERING PLANNED TISSUE PRINTING & INCUBATION • Scaffold materials • Bio-ink formulations • Software development © 2021 ALL RIGHTS RESERVED WWW.MEATECH3D.COM 14 MEATECH’S CELL-BASED PROCESS VISION PRODUCING CULTURED FAT AND MUSCLE CELLS FAT MUSCLE CELL COLLECTION GROWING CELLS DIFFERENTIATING GROUND PRODUCTS CELLS Cell lines are Stem cells are transferred Upon reaching sufficient Unstructured cell-based developed to reliably to bioreactors for cell quantities, stem cells products (beef or chicken): express particular exponential growth under are differentiated into fat fat, ground, hybrid or characteristics. ideal conditions. and muscle cells. formed. © 2021 ALL RIGHTS RESERVED WWW.MEATECH3D.COM 15 MEATECH'S CULTURED STEAK VISION A FLEXIBLE MANUFACTURING PROCESS FOR 3D PRINTED TISSUE FAT MUSCLE BIO-INKS 3D BIOPRINTING INCUBATION STRUCTURED MEAT Bio-inks formulated from Bio-inks are accurately Printed product is Produced in fraction our cell lines and unique printed to assemble cells incubated to mature and of time required to scaffolding materials are as they would be found form tissue. achieve same cut via loaded into our 3D in a conventional cut of conventional means. bioprinter. muscle. © 2021 ALL RIGHTS RESERVED WWW.MEATECH3D.COM 16 TARGETING ALL CULTURED MEAT CATEGORIES + + ORGANOLEPTIC 3D PRINTED PROPERTIES CULTURED MEAT + + + 3d bioprinter TIME TO MARKET © 2021 ALL RIGHTS RESERVED WWW.MEATECH3D.COM 17 USE OF FUNDS: UPSCALING PATHWAY Manufacturing plant SCALING OUR TECHNOLOGY FROM THE LAB TO AN INDUSTRIAL PROCESS FOR LARGE-SCALE PRODUCTION OF MEAT 2.0 PRODUCTS Key criteria are: • Capabilities of the cell line being used Pilot plant • Formulation of the cell-culturing media and reduction in costs • Management of the bioreactor hardware In 2020, MeaTech employed lab-scale bioreactors to produce muscle and fat cells for experimental tissue bioprinting. Lab scale © 2021 ALL RIGHTS RESERVED WWW.MEATECH3D.COM 18 MEATECH'S INTELLECTUAL PROPERTY PATENT PORTFOLIO Cultured Edible Meat Harvesting Bovine Fabrication Using Embryonic Inner Cell Mass Bioprinting Physical Manipulation of Bioprinter Print Head Cultured Tissue Growth Support For Cell Bovine Umbilical Cord Culture Stem Cells As Feeder Layer © 2021 ALL RIGHTS RESERVED WWW.MEATECH3D.COM 19 ABOUTABOUT US US © 2021 ALL RIGHTS RESERVED WWW.MEATECH3D.COM 20 OUR LEADERSHIP SHARON FIMA OMRI SCHANIN STEVEN H. LAVIN GUY HEFER CEO & CO-FOUNDER COO & CO-FOUNDER CHAIRMAN CFO Sharon is an entrepreneur with Omri is a co-Founder of MeaTech Mr. Lavin serves as Vice Chairman Guy has broad international business over 20 years of experience in and its astute COO focused on of OSI Group, LLC, a privately held experience with a successful track the printing industry. Sharon supporting cross-functional teams to company and a global supplier record of transaction generation and was a co-founder and the CTO see R&D achieve commercialization. of value-added food and meat execution. Prior to joining MeaTech of Nano Dimension (NNDM) and Omri has a successful history of products. Mr. Lavin is the President Guy was the CFO of a tech-focused spearheaded the development of entrepreneurship in a variety of of Lavin & Gedville, a boutique law holding company. Prior
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