Carcinogenesis Foundation, USA In association with Reliance Life Sciences presents

INTERNATIONAL SYMPOSIUM ON “Frontiers in Carcinogenesis and Cancer Prevention: Scientific Endeavors and Public Health Initiatives”

FEBRUARY 5-7, 2010

Venue: Dhirubhai Ambani Life Sciences Centre, -Belapur Road, Rabale, , India International Scientific Committee

Prof. Gopala Kovvali, Ph.D., (Conference Co-Chair) President, Carcinogenesis Foundation, USA

Dr. Dhananjaya Saranath, Ph.D., FMAS, The facilitation of continued advances in cancer care, (Conference Co-Chair) Research Director, Reliance Life Sciences, Mumbai, India prevention, treatment and control require an in-depth Dr. Balasubramaniam Anandh, MCh., DNB, knowledge of the mechanism of genesis of cancer at the Neurosurgeon, KDA Hospital & Medical cellular/molecular level. Significant progress has been made in Research Institute, Mumbai,India cancer research in the past decade. An international Dr. Rajendra Badwe, MS, conference to disseminate information on the major Director - Tata Memorial Centre, Mumbai, India breakthroughs to the general public and create an opportunity Prof. Paul Brandt-Rauf, P.H., M.D., Sc.D., Dean, UIC School of Public Health, Chicago for the researchers to critically analyze the progress and Prof. C.C. Lin Ph.D., Director, challenges is therefore, very timely and important. Cytogenetics Laboratory, China Medical College Hospital, Taichung, Taiwan (R.O.C) Reliance Life Sciences in association with the Carcinogenesis Prof. Fu-Li Yu, Ph.D., Foundation, USA is proud to present an International Professor of Biochemistry (Emeritus) Symposium on “Frontiers in Carcinogenesis and Cancer University of Illinois College of Medicine, Chicago, Illinois, USA Prevention: Scientific Endeavors and Public Health Initiatives”. Dr. Arnab Kapat, Ph.D., Director, The international conference will bring together clinicians and Reliance Institute of Life Sciences, research scientists in the field of cancer to discuss and Mumbai, India deliberate on the progress made in the field during the first Prof. Paturu Kondaiah, Ph.D., Dept. of Molecular Reproduction & decade of the new millennium. Topics for discussions include Developmental Genetics, identification of novel molecular targets for developing Indian Institute of Science, Bangalore, India therapeutic and prevention strategies. Dr. Shubha Maudgal, Ph.D., Director, New Projects, Cancer Patients Aids Association, Mumbai, India. Cancer being a major public health issue in the developing Dr. Manoj Pandey, MS, world, there will be focused sessions on spreading cancer Department of Surgical Oncology, prevention education. The conference will have oral Institute of Medical Sciences, Banaras Hindu University, India presentations, panel discussions and poster presentations to Prof. M. Radhakrishna Pillai, share the research findings from the seasoned researchers and FRCPath, Ph.D., FASc, FNASc, clinicians, as well as young budding scientists and clinicians. Director, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, India The international conference is expected to catalyze scientific Prof. Ravi Salgia, MD, Ph.D., discussions that could initiate paradigm shifts in approaches to Department of Medicine, cancer research, cancer patients and oncologists. University of Chicago, Illinois, USA Dr. Rajiv Sarin, MD, DMRT, FRCR, Director ACTREC, Mumbai, India

Prof. Takuji Tanaka, MD, Ph.D., Chairman, Department of Oncologic Pathology, Kanazawa Medical University, Ishikawa, Japan

Prof. James Trosko, Ph.D., Center for Integrative Toxicology Michigan State University, Michigan

Dr. Jamboor K. Vishwanatha, Ph.D. Dean, Graduate School of Biomedical Sciences, Univ. of North Texas Health Science Center, Texas, USA Distinguished speakers at the Symposium

Dr. Gopala Kovvali, Ph.D., President, Carcinogenesis Foundation Executive Editor, Journal of Carcinogenesis Adjunct Professor of Genetics, Rutgers University, NJ, USA Dr. Kovvali has published several research papers on DNA repair mechanisms to his credit. Dr. Kovvali's current interests are in cancer prevention, education and public health related issues. Currently, Dr. Gopala Kovvali works in private sector and is an Adjunct Professor in the Department of Genetics, Rutgers University, NJ, and Executive Editor of the Journal of Carcinogenesis, and was the founding Editor-in-Chief. Dr. Kovvali is a founder president of Carcinogenesis Foundation, a non-profit organization that strives to understand the genesis of cancers in order to prevent cancer incidence.

Dr. Dhananjaya Saranath, Ph.D., FMAS Research Director, Molecular Medicine, Reliance Life Sciences, Mumbai, India Dr. Saranath, Research Director, heads the Molecular Medicine Group of Reliance Life Sciences. She is a Fellow of Academy of Sciences, India, Founder Member and Member at Large of Council of the International Academy of Oral Oncology, and was the Past President of the Indian Association of Cancer Research. Dr. Saranath has done pioneering work towards understanding the molecular basis of Oral Cancer. Her current research in translational medicine aims to develop 'Predictive / Preventive Molecular Biomarkers' in human cancers, genetic diseases and infectious diseases, with emphasis on 'Diagnosis for All' in the high end Molecular Diagnostics. She has authored over 70 publications.

Dr. Shubha Maudgal, Ph.D., Director, New Projects, Cancer Patients Aids Association, Mumbai, India. Dr. Maudgal is PhD from the prestigious Indian Institute of Technology, Bombay. After extensive experience in the field of high temperature resistant polymers, in various Corporate Organisations, Dr. Maudgal joined Cancer Patients Aids Association in 1999. Since then she has been involve in cancer awareness program, running an interactive website for cancer patients and family members, organising and overseeing volunteer counselling and training programs for patient support groups, and supports cancer related research activities.

Dr. Eduardo Franco, M.P.H, Dr. P.H., Professor of Epidemiology and Oncology and Director, Division of Cancer Epidemiology, McGill University's Faculty of Medicine, Montreal, Canada Professor Franco's research has focussed on molecular epidemiology and prevention of cervical cancer, upper aero-digestive tract cancers and childhood tumours, and the development of statistical methods for evaluating efficacy of cancer screening strategies and assessing the impact of measurement error in epidemiology. He has published over 290 papers on these topics and edited two books on cancer epidemiology and prevention.

Dr. David A Potter, M.D., Ph.D., Department of Medicine, University of Minnesota, Minneapolis, USA Dr. Potter's research interests include studies on the roles of calpain proteases in cancer, the role of heat shock protein 90 (hsp 90) in breast cancer, and translational breast cancer clinical trials. He is also studying regulation of calpain proteases and the role in cytoskeletal remodeling; the role of cytochrome P450 in breast cancer progression.

Dr. Mary E Reid, Ph.D., Associate Professor of Oncology, Director of Collaborative Research, Roswell Park Cancer Institute, USA Dr. Reid's research interests focus on early detection and chemoprevention of lung and head and neck cancers, and the evaluation of genetic/epigenetic biomarkers of early lesions in high risk populations. She has authored more than 50 publications. Distinguished speakers at the Symposium

Dr. James E Trosko, Ph.D., Center for Integrative Toxicology, Michigan State University, USA Dr. Trosko pioneered the studies on the mechanisms of tumor promotion, leading to the discovery of tumor promoter and oncogene inhibition of gap junctional intercellular communication (GJIC). More recently, his team pioneered the isolation of human adult stem cells, identified a genetic marker for normal adult stem cells and showed that “cancer stem cells” could be derived from these normal adult stem cells. Today, his research is a systems integration of how environmental and dietary factors, acting during pre and post-natal development can modify frequency of cancer, supporting the “Barker hypothesis”.

Dr. Victoria M Villaflor, MD, Assistant Professor, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois, USA Dr. Victoria M Villaflor is currently Assistant Professor in the Department of Medicine in the Section of Hematology and Oncology at the University of Chicago, Chicago. Dr. Villaflor currently focuses her research efforts on clinical care of patients with head and neck, esophageal and lung cancers. Her major research interests include combined chemoradiotherapy as well as targeted therapies to improve clinical outcomes in patients with head and neck, esophageal and lung carcinoma.

Dr. Jamboor K Vishwanatha, Ph.D., Professor of Molecular Biology and Immunology, Director, Texas Center for Health Disparities, University of North Texas Health Science Center, Fort Worth, Texas, USA Dr. Vishwanatha's research is in the area of cancer cell proliferation. He has published on molecular markers that exhibit differences between prostate cancer incidence in patients from USA and India. His laboratory is also investigating molecular markers for malignant progression of oral dysplasia, and utilization of nanotechnology to deliver drugs and biomolecules for therapy.

Prof. Haim Werner, Ph.D., Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel Prof. Werner is a leader in the field of the insulin-like growth factors (IGFs) and, in particular, the role and regulation of the IGF receptor. A prolific researcher, he is the author of over 135 papers.

Dr. Saikrishna Yendamuri, M.D., Assistant Professor of Oncology, Roswell Park Cancer Institute, New York, USA Dr. Yendamuri is a thoracic surgeon at the Roswell Park Cancer Institute in New York. His lab focuses on translating the ability of microRNA expression profiles in the early detection and prognostication of lung cancer. Dr.Yendamuri's clinical interests include minimally invasive lung surgery, TEMLA (transcervical extended mediastinal lymphadenectomy) and airway surgery. He has authored several manuscripts and book chapters in the clinical arena as well as in lung cancer genetics.

Paul W. Brandt-Rauf, Dr. P.H., M.D., Sc.D., UIC School of Public Health, Chicago Dr. Paul W. Brandt-Rauf is currently the Dean of the School of Public Health at the University of Illinois at Chicago, and holds several prestigious appointments as Professor of Environmental and Occupational Health Sciences in the School of Public Health, Professor of Medicine in the College of Medicine. Dr. Brandt-Rauf's major research interests include environmental carcinogenesis, with emphasis on the molecular biology and the molecular epidemiology of cancer-related proteins, gene-environment interactions and the development of new therapeutic/preventive interventions. He has authored over 220 journal articles and book chapters. Registration fees: §Delegates from India and South Asia ...... INR 3,000/- Contact Secretariat: §Delegates from other countries ...... USD 300/- Delegates/students may contact Early Registration: Before December 05, 2009 [email protected] §Delegates from India and South Asia ...... INR 2,000/- regarding any §Delegates from other countries ...... USD 200/- queries/assistance. Registration fees would cover for: Or call Baby Jaisen • Participation in the 3-day conference • Bag/folder with Book of Abstract; on 91-22-67678384. • Lunch on all three days • Conference Dinner on Day 2 • High Tea on final day • Tea/Coffee/Biscuits through the conference

Last date of registration: January 15, 2010 Late fee of INR 500/- or USD 50/- would be charged after the due date.

Mode of Payment Demand Draft/Cheque favoring ‘Reliance Life Sciences Pvt. Ltd.’ can be sent by Carcinogenesis Foundation registered post to the Secretariat at Reliance Life Sciences Pvt. Ltd., Dhirubhai Ambani 614 Overdell Drive Life Sciences Centre, Thane-Belapur Road, Rabale, Navi Mumbai - 400 701, INDIA. Sugar Land Delegates from USA may send the registration fees by cheque to the foundation’s office Texas 77479, USA in USA. Cheque should be payable to ‘Carcinogenesis Conference 2010’. Those Ph: ( 877) 225 7814 (Toll-free) interested in paying by credit card may please visit http://symposium.rellife.com for Fax: (877) 255 7661 (Toll-free) symposium registration.

Venue: The Symposium will be held at the Reliance Life Sciences' headquarters, Dhirubhai Ambani Life Sciences Centre, Navi Mumbai, India.

Accomodation: Guesthouse accommodation will be made available at nominal charges to delegates from outside India on request, subject to availability. Hotel Bookings on payment will be facilitated for the delegates on request.

Recommended Hotels (Delegates may book directly or request organizers to facilitate) • Hotel South Coast/ Hotel Sai Nidhi, Rabale, Navi Mumbai • Hotel Renaissance, , Mumbai Organizers can help delegates with information on the stay charges/email address of hotel on request.

Abstracts: Abstracts are invited from participants for poster/oral presentations and should outline the rationale, objectives, brief work plan and findings of the study. The text should not exceed 250 words (Font: Arial; Size: 11 with single space). Abstracts must be submitted by January 05, 2010. A soft copy in MS Word format should be mailed to [email protected] with the subject line mentioning the word 'Abstract'. The best ten abstracts will be selected for oral presentations and others will be given poster presentations. Citations will be given to best oral/poster presentations and two of the best oral and poster presentations will receive awards.

Local Weather The climate in Mumbai throughout the year is temperate from being hot and humid in summer to being pleasant in winter. Pleasant day highs of 27°C and cool nights of around 15°C can be expected in February.

Language English, the language of the Symposium, is a widely used and understood language amongst the urban population in most cities of India.

Visa requirement Overseas participants will need to have a valid passport and visa to enter India. Details about visa requirements should be obtained from the Indian Embassies in respective countries. About Reliance Life Sciences (RLS) Reliance Life Sciences, incorporated in the year 2001 is a new millennium initiative of the Reliance Group. Reliance Life Sciences is developing business opportunities in the domains of medical, plant and industrial biotechnology. From a domain perspective, these opportunities cover Biopharmaceuticals, Pharmaceuticals, Clinical Research Services, Regenerative Medicine, Molecular Medicine, Novel Therapeutics, BioFuels, Plant Tissue Culture, Plant Metabolic Engineering and Industrial Biotechnology. From an integration perspective, these opportunities encompass Repositories, Research, Process Development, Pre-clinical Studies, Human Clinical Trials, Commercial-scale Manufacture and Marketing, all of which are carried out in-house. About Carcinogenesis Foundation, USA Carcinogenesis Foundation is a USA based non profit organization consisting of scientists, physicians and general public around the world interested in global cancer prevention efforts. The mission of the foundation is to contribute to understanding of the cancer causing processes with a primary goal to prevent incidence of cancers around the world. The foundation strives to advance its mission through Research and Education by fostering community participation and partnership. The foundation works collaboratively with academic institutions, pharmaceutical and biotechnology companies and other non-profit organizations to identify ways and means to achieve the goals of the foundation.

Carcinogenesis foundation undertakes activities in four areas - Research, Awareness, Care and Education (RACE).The foundation publishes Journal of Carcinogenesis, which is a peer-reviewed professional journal in the field of carcinogenesis and carcinoprevention research. The foundation publishes a bi-monthly newsletter, CarciKnow News, which is the "Voice of the foundation".

Foundation envisages to undertake community education by implementing a novel program- Community Health and Science Education (CHASE) program

Reliance Life Sciences Pvt. Ltd. Dhirubhai Ambani Life Sciences Centre, Thane-Belapur Road, Rabale, Navi Mumbai - 400 701, INDIA. Tel: +91 22 6767 8000 • Fax: +91 22 6767 8099 • www.rellife.com

This information is published in good faith and is believed to be reliable. While every effort has been made to ensure the accuracy of the information provided, no responsibility will be taken by Reliance Life Sciences (RLS) for any errors that may have occurred. RLS shall not be liable for any damages caused as a result of the use of the information contained herein.