RT² Profiler PCR Array (384-Well Format) Rhesus Macaque Inflammatory Response & Autoimmunity

Cat. no. 330231 PAQQ-3803ZE

For pathway expression analysis

Format For use with the following real-time cyclers

RT² Profiler PCR Array, Applied Biosystems® models 7900HT (384-well block), Format E ViiA™ 7 (384-well block); Bio-Rad CFX384™

RT² Profiler PCR Array, Roche® LightCycler® 480 (384-well block) Format G

Description

The Rhesus Macaque Inflammatory Response & Autoimmunity 384HT RT² Profiler PCR Array profiles the expression of 370 key involved in autoimmune and inflammatory responses, as well as innate and adaptive immune responses. Inflammation is a complex and important cellular and humoral biological response to and/or contributor to many pathological conditions, such as autoimmune disorders, infection, injury, cardiovascular disease, neurodegenerative disorders, oncogenesis, stress, and many others. This array profiles the expression of genes demonstrating differential regulation at the transcriptional level during the immune cascade reactions involved in these responses. These genes encode , chemokines, and their receptors, (including specific T helper cell markers), as well as mediators of -receptor interactions and cytokine production and metabolism. Thoroughly researched panels of genes involved in the acute-phase, inflammatory, and humoral immune responses, as well as Toll-like receptor signaling are also represented. Using real-time PCR, research studies can easily and reliably analyze expression of a focused panel of genes related to inflammatory and autoimmune responses with this array.

For further details, consult the RT² Profiler PCR Array Handbook.

Sample & Assay Technologies Shipping and storage

RT² Profiler PCR Arrays in formats E and G are shipped at ambient temperature, on dry ice, or blue ice packs depending on destination and accompanying products.

For long term storage, keep plates at –20°C.

Note: Ensure that you have the correct RT² Profiler PCR Array format for your real-time cycler (see table above).

Note: Open the package and store the products appropriately immediately on receipt.

Gene table: RT² Profiler PCR Array

Position UniGene GenBank Symbol Description A01 Mmu.17311 NM_001105162 ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 A02 Mmu.15054 XM_001104328 ADORA1 Adenosine A1 receptor A03 Mmu.11903 XM_001091623 AHSG Alpha-2-HS-glycoprotein A04 Mmu.3528 NM_001047118 AIF1 Allograft inflammatory factor 1 A05 Mmu.2604 XM_001083775 AIMP1 Aminoacyl tRNA synthetase complex-interacting multifunctional 1 A06 Mmu.3004 XM_001117975 APOA2 Apolipoprotein A-II A07 Mmu.3212 XM_001103860 BCL6 B-cell CLL/lymphoma 6 A08 N/A XM_001100700 BLNK B-cell linker A09 Mmu.2085 XM_001102441 BMP1 Bone morphogenetic protein 1 A10 N/A XM_001115987 BMP2 Bone morphogenetic protein 2 A11 N/A XM_001089525 BMP3 Bone morphogenetic protein 3 A12 Mmu.16127 XM_001089245 BMP7 Bone morphogenetic protein 7 A13 Mmu.3133 XM_001091921 C3 Complement component 3 A14 N/A XM_001113373 C3AR1 Complement component 3a receptor 1 A15 N/A XM_001095750 C5 Complement component 5 A16 Mmu.13872 XM_001091928 CAST Calpastatin A17 Mmu.3702 NM_001032849 CCL1 Chemokine (C-C motif) ligand 1 A18 Mmu.3651 NM_001032874 CCL11 Chemokine (C-C motif) ligand 11 A19 Mmu.15592 XM_001113462 CCL13 Chemokine (C-C motif) ligand 13 A20 Mmu.3705 NM_001032852 CCL17 Chemokine (C-C motif) ligand 17 A21 Mmu.3706 NM_001032853 CCL18 Chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) A22 Mmu.3707 NM_001032959 CCL19 Chemokine (C-C motif) ligand 19 A23 Mmu.3491 NM_001032821 CCL2 Chemokine (C-C motif) ligand 2 A24 Mmu.3708 NM_001032854 CCL20 Chemokine (C-C motif) ligand 20 B01 Mmu.3682 NM_001032855 CCL21 Chemokine (C-C motif) ligand 21 B02 Mmu.1186 NM_001032946 CCL23 Chemokine (C-C motif) ligand 23 B03 Mmu.19084 XM_001109757 CCL24 Chemokine (C-C motif) ligand 24 B04 Mmu.3709 NM_001032875 CCL25 Chemokine (C-C motif) ligand 25 B05 Mmu.3710 NM_001032876 CCL27 Chemokine (C-C motif) ligand 27 B06 Mmu.3711 NM_001032877 CCL28 Chemokine (C-C motif) ligand 28 B07 Mmu.3703 NM_001034200 CCL3 Chemokine (C-C motif) ligand 3 B08 Mmu.3698 NM_001032850 CCL5 Chemokine (C-C motif) ligand 5 B09 Mmu.3704 NM_001032851 CCL8 Chemokine (C-C motif) ligand 8 B10 Mmu.3419 NM_001032858 CCR1 Chemokine (C-C motif) receptor 1 B11 Mmu.15553 XM_001111554 CCR10 Chemokine (C-C motif) receptor 10 B12 Mmu.3460 NM_001032806 CCR2B B13 Mmu.10058 NM_001047140 CCR3 Chemokine (C-C motif) receptor 3 B14 Mmu.14927 XM_001098807 CCR4 Chemokine (C-C motif) receptor 4 B15 Mmu.3440 NM_001042773 CCR5 Chemokine (C-C motif) receptor 5 B16 Mmu.3681 NM_001032935 CCR6 Chemokine (C-C motif) receptor 6 B17 Mmu.9824 NM_001032884 CCR7 Chemokine (C-C motif) receptor 7 B18 N/A XM_001084047 CCR8 Chemokine (C-C motif) receptor 8 B19 Mmu.14969 XM_001114447 CCR9 Chemokine (C-C motif) receptor 9 B20 Mmu.14937 XM_001115492 CCRL1 Chemokine (C-C motif) receptor-like 1 B21 Mmu.11968 NM_001130433 CD14 CD14 molecule B22 Mmu.1817 XM_001104337 CD27 CD27 antigen-like B23 Mmu.3578 NM_001042641 CD28 CD28 molecule B24 Mmu.3291 NM_001042662 CD4 CD4 molecule C01 N/A XM_001104333 CD40 CD40 molecule, TNF receptor superfamily member 5 C02 Mmu.3581 NM_001032839 CD40LG CD40 ligand Position UniGene GenBank Symbol Description C03 N/A XM_001088935 CD70 CD70 antigen-like C04 Mmu.3050 XM_001099491 CD74 CD74 molecule, major histocompatibility complex, class II invariant chain C05 Mmu.3359 NM_001042642 CD80 CD80 molecule C06 Mmu.3580 NM_001042644 CD86 CD86 molecule C07 Mmu.15312 XM_001084053 CKLF Chemokine-like factor C08 N/A XM_001118423 CLEC4E C-type lectin domain family 4, member E C09 Mmu.13765 XM_001085127 CMTM2 CKLF-like MARVEL transmembrane domain containing 2 C10 N/A XM_001097304 CNTFR Ciliary neurotrophic factor receptor C11 Mmu.11203 XM_001095225 CREBBP CREB binding protein C12 Mmu.3013 XM_001117250 CRP C-reactive protein, pentraxin-related C13 N/A XM_001090841 CSF1 Colony stimulating factor 1 (macrophage) C14 Mmu.3665 NM_001032949 CSF2 Colony stimulating factor 2 (granulocyte-macrophage) C15 Mmu.1176 XM_001086084 CSF2RB Colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) C16 Mmu.15567 XM_001095097 CSF3 Colony stimulating factor 3 (granulocyte) C17 Mmu.15159 XM_001111241 CSF3R Colony stimulating factor 3 receptor (granulocyte) C18 N/A XM_001103315 CTF1 C19 Mmu.3582 NM_001044739 CTLA4 Cytotoxic T-lymphocyte-associated protein 4 C20 Mmu.3716 NM_001032881 CX3CL1 Chemokine (C-X3-C motif) ligand 1 C21 Mmu.13364 XM_001084526 CX3CR1 Chemokine (C-X3-C motif) receptor 1 C22 Mmu.3712 NM_001032878 CXCL1 Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) C23 Mmu.2740 NM_001032892 CXCL10 Chemokine (C-X-C motif) ligand 10 C24 Mmu.2724 NM_001032950 CXCL11 Chemokine (C-X-C motif) ligand 11 D01 Mmu.3714 NM_001032934 CXCL12 Chemokine (C-X-C motif) ligand 12 D02 Mmu.3684 NM_001032880 CXCL13 Chemokine (C-X-C motif) ligand 13 D03 Mmu.9991 XM_001110657 CXCL14 Chemokine (C-X-C motif) ligand 14 D04 N/A XM_001091762 CXCL5 Chemokine (C-X-C motif) ligand 5 D05 Mmu.1051 XM_001103136 CXCL6 Chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) D06 Mmu.3647 NM_001032936 CXCL9 Chemokine (C-X-C motif) ligand 9 D07 Mmu.9522 NM_001040420 CXCR1 Chemokine (C-X-C motif) receptor 1 D08 Mmu.8534 NM_001145040 CXCR3 Chemokine (C-X-C motif) receptor 3 D09 Mmu.2390 NM_001042645 CXCR4 Chemokine (C-X-C motif) receptor 4 D10 Mmu.15717 XM_001100017 CXCR5 Chemokine (C-X-C motif) receptor 5 D11 Mmu.10862 NM_001047141 CXCR6 Chemokine (C-X-C motif) receptor 6 D12 Mmu.9959 XM_001083654 CYBB Cytochrome b-245, beta polypeptide (chronic granulomatous disease) D13 N/A XM_001082424 EDA Ectodysplasin A D14 Mmu.11401 XM_001109474 EPHX2 Epoxide hydrolase 2, cytoplasmic D15 Mmu.3292 NM_001042736 EPO D16 N/A XM_001105833 EPOR V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma D17 N/A XM_001090430 ERBB2 derived oncogene homolog (avian) D18 Mmu.13520 XM_001088781 ERBB2IP Erbb2 interacting protein D19 Mmu.15082 XM_001117664 F11R F11 receptor D20 Mmu.11082 NM_001104585 F2 Coagulation factor II (thrombin) D21 N/A XM_001104233 F3 Coagulation factor III (thromboplastin, tissue factor) D22 N/A XM_001090980 F8 Coagulation factor VIII, procoagulant component D23 Mmu.3579 NM_001032838 FASLG Fas ligand (TNF superfamily, member 6) D24 Mmu.19076 NM_001193950 FGF10 Fibroblast growth factor 10 E01 Mmu.18916 XM_001094765 FGF12 Fibroblast growth factor 12 E02 Mmu.3766 XM_001099284 FGF2 Fibroblast growth factor 2 (basic) E03 Mmu.745 XM_001113805 FGF7 Fibroblast growth factor 7 E04 N/A XM_001101077 FIGF C-fos induced growth factor (vascular endothelial growth factor D) E05 N/A XM_001113150 FLT3L Fms-related tyrosine kinase 3 ligand E06 Mmu.1285 XM_001083548 FN1 Fibronectin 1 E07 Mmu.1563 NM_001098399 FOS FBJ murine osteosarcoma viral oncogene homolog E08 Mmu.16194 XM_001108337 GATA3 GATA binding protein 3 E09 N/A XM_001109523 GDF2 Growth differentiation factor 2 E10 Mmu.13047 XM_001112644 GDF3 Growth differentiation factor 3 E11 Mmu.16110 XM_001099806 GDF5 Growth differentiation factor 5 E12 Mmu.1089 XM_001090825 GDF6 Growth differentiation factor 6 E13 Mmu.13454 XM_001099499 GFI1 Growth factor independent 1 transcription repressor E14 Mmu.12560 XM_001094722 GFRA1 GDNF family receptor alpha 1 E15 Mmu.3595 NM_001042667 GHR Growth hormone receptor E16 Mmu.13995 XM_001099081 GLMN Glomulin, FKBP associated protein E17 Mmu.15889 XM_001089255 GPC1 Glypican 1 E18 Mmu.17186 XM_001109998 GPI Glucose phosphate isomerase E19 N/A XM_001084746 GPR44 G protein-coupled receptor 44 E20 N/A XM_001091059 GPR68 G protein-coupled receptor 68 E21 Mmu.3599 NM_001032848 GREM1 Gremlin 1 E22 N/A XM_001095526 GREM2 Gremlin 2 E23 N/A XM_001088286 HRH1 Histamine receptor H1 E24 Mmu.15916 XM_001104581 ICOS Inducible T-cell co-stimulator Position UniGene GenBank Symbol Description F01 N/A XM_001107576 IFNA14 Interferon, alpha 14 F02 Mmu.15665 NM_001135794 IFNA2 Interferon, alpha 2 F03 N/A XM_001107458 IFNA8 Interferon, alpha 8 F04 Mmu.14907 XM_001092098 IFNAR1 Interferon (alpha, beta and omega) receptor 1 F05 N/A XM_001092342 IFNAR2 Interferon (alpha, beta and omega) receptor 2 F06 Mmu.15664 NM_001135795 IFNB1 Interferon, beta 1, fibroblast F07 Mmu.3373 NM_001032905 IFNG Interferon-gamma F08 Mmu.822 XM_002803880 IFNGR1 receptor 1 F09 Mmu.12225 XM_001091864 IFNGR2 Interferon gamma receptor 2 (interferon gamma transducer 1) F10 Mmu.19482 XM_001104958 IFNK Interferon, kappa F11 N/A XM_001108113 IFNW1 Interferon, omega 1 F12 N/A XM_001093144 IGSF6 Immunoglobulin superfamily, member 6 F13 Mmu.11069 XM_001096913 IKBKB Inhibitor of kappa light polypeptide enhancer in B-cells, kinase beta F14 Mmu.3374 NM_001044727 IL10 Interleukin 10 F15 Mmu.12155 XM_001092736 IL10RA Interleukin 10 receptor, alpha F16 Mmu.2498 XM_001094340 IL10RB Interleukin-10 receptor subunit beta-like F17 Mmu.15672 XM_001093448 IL11RA Interleukin 11 receptor, alpha F18 Mmu.3360 NM_001044734 IL-12A Interleukin 12A Interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte F19 Mmu.3413 NM_001044725 IL12B maturation factor 2, p40) F20 Mmu.3505 XM_001115186 IL12RB1 Interleukin 12 receptor, beta 1 F21 Mmu.12301 XM_001094235 IL12RB2 Interleukin 12 receptor, beta 2 F22 Mmu.3675 NM_001032929 IL13 Interleukin 13 F23 Mmu.3414 NM_001044731 IL15 Interleukin 15 F24 Mmu.10866 NM_001079517 IL15RA Interleukin 15 receptor, alpha G01 Mmu.2764 NM_001032808 IL16 Interleukin 16 G02 Mmu.14785 XM_001106391 IL17A Interleukin 17A G03 N/A XM_001106071 IL17B Interleukin 17B G04 N/A XM_001106517 IL17F Interleukin-17F-like G05 Mmu.16084 XM_001102483 IL17RA Interleukin 17 receptor A G06 N/A XM_001082504 IL17RB Interleukin 17 receptor B G07 Mmu.162 XM_001091392 IL17RE Interleukin 17 receptor E G08 Mmu.3545 NM_001032834 IL18 Interleukin 18 (interferon-gamma-inducing factor) G09 N/A XM_001108108 IL18RAP Interleukin 18 receptor accessory protein G10 Mmu.3361 NM_001042757 IL1A Interleukin 1, alpha G11 Mmu.648 NM_001042756 IL1B Interleukin 1, beta G12 N/A XM_001093641 IL1F5 Interleukin 36 receptor antagonist G13 N/A XM_001093517 IL1F6 Interleukin 36, alpha G14 N/A XM_001091119 IL1F8 Interleukin 36, beta G15 N/A XM_001090647 IL1F9 Interleukin 36, gamma G16 Mmu.12735 XM_001107510 IL1R1 Interleukin 1 receptor, type I G17 Mmu.2997 NM_001047134 IL1R2 Interleukin 1 receptor, type II G18 Mmu.3670 NM_001032960 IL1RAP Interleukin 1 receptor accessory protein G19 N/A XM_001092265 IL1RAPL2 Interleukin 1 receptor accessory protein-like 2 G20 Mmu.15834 XM_001107813 IL1RL1 Interleukin 1 receptor-like 1 G21 N/A XM_001107630 IL1RL2 Interleukin 1 receptor-like 2 G22 Mmu.15827 XM_001091717 IL1RN Interleukin 1 receptor antagonist G23 Mmu.3415 NM_001047130 IL2 Interleukin 2 G24 Mmu.15063 XM_001084726 IL20 Interleukin 20 H01 N/A XM_001097436 IL20RA Interleukin 20 receptor, alpha H02 Mmu.18852 XM_001103613 IL21 Interleukin 21 H03 Mmu.13971 XM_001094102 IL21R Interleukin 21 receptor H04 Mmu.18853 XM_001117159 IL22 Interleukin 22 H05 N/A XM_001113239 IL22RA1 Interleukin 22 receptor, alpha 1 H06 Mmu.18854 XM_001115026 IL23A Interleukin 23, alpha subunit p19 H07 N/A XM_001093896 IL23R Interleukin 23 receptor H08 Mmu.9304 XR_010062 IL24 Interleukin-24-like H09 N/A XM_001117154 IL26 Interleukin 26 H10 Mmu.3810 NM_001032917 IL2RA Interleukin 2 receptor, alpha H11 Mmu.12296 XM_001085792 IL2RB Interleukin 2 receptor, beta H12 Mmu.1871 NM_001035529 IL2RG Interleukin 2 receptor, gamma H13 Mmu.16387 NM_001101734 IL3 Interleukin 3 (colony-stimulating factor, multiple) H14 Mmu.3375 NM_001032904 IL4 Interleukin 4 H15 Mmu.3507 XM_001093763 IL4R Interleukin 4 receptor H16 Mmu.3362 NM_001047133 IL5 Interleukin 5 (colony-stimulating factor, eosinophil) H17 Mmu.14997 XM_001100843 IL5RA Interleukin 5 receptor, alpha H18 Mmu.3376 NM_001042733 IL6 Interleukin 6 (interferon, beta 2) H19 Mmu.13612 XM_001114404 IL6R Interleukin 6 receptor H20 Mmu.1082 XM_001100601 IL6ST Interleukin 6 signal transducer (gp130, receptor) H21 Mmu.3574 NM_001032846 IL7 Interleukin 7 H22 Mmu.12488 XM_001092582 IL7R Interleukin 7 receptor Position UniGene GenBank Symbol Description H23 Mmu.3363 NM_001032965 IL8 Interleukin 8 H24 N/A XM_001088762 IL8RB Interleukin 8 receptor, beta I01 Mmu.15228 XM_001100521 IL9R Interleukin 9 receptor I02 Mmu.3798 NM_001032955 INHA Inhibin, alpha I03 N/A XM_001098514 INHBA Inhibin, beta A I04 Mmu.3799 XM_001090729 INHBB Inhibin, beta B I05 Mmu.13250 XM_001090790 IRAK2 Interleukin-1 receptor-associated kinase 2 I06 Mmu.11578 XM_001104294 IRF1 Interferon regulatory factor 1 I07 Mmu.15461 XM_001094391 IRF4 Interferon regulatory factor 4 I08 Mmu.11935 NM_001136100 IRF7 Interferon regulatory factor 7 I09 Mmu.1177 XR_012415 ITGB2 Integrin beta-2-like I10 Mmu.11895 XM_001085586 ITIH4 Inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein) I11 Mmu.2703 XM_002801620 JAK1 1 I12 Mmu.12996 XM_001082883 JAK2 I13 Mmu.3676 XM_001101381 KITLG KIT ligand I14 Mmu.9776 XM_001101685 KNG1 Kininogen 1 I15 Mmu.16029 XM_001108923 LAG3 Lymphocyte-activation gene 3 I16 Mmu.12152 XM_001102058 LAT Linker for activation of T cells I17 Mmu.3027 XM_001094451 LBP Lipopolysaccharide binding protein I18 N/A XM_001092988 LEFTY1 Left-right determination factor 1 I19 N/A XM_001092296 LEFTY2 Left-right determination factor 2 I20 Mmu.1248 NM_001032819 LEPR Leptin receptor I21 N/A XM_001082842 LIFR Leukemia inhibitory factor receptor alpha I22 Mmu.2000 XM_001083469 LOC694029 Apolipoprotein L2-like I23 N/A XM_001085768 LOC697161 Interleukin-29-like I24 N/A XM_001087517 LOC699050 Granulocyte-macrophage colony-stimulating factor receptor subunit alpha-like J01 N/A XM_001087874 LOC699418 Eosinophil lysophospholipase-like J02 N/A XM_001088828 LOC700588 ligand superfamily member 9-like J03 N/A XM_001103025 LOC704750 Cytochrome P450 26B1-like J04 N/A XM_001100470 LOC705678 Caspase recruitment domain-containing protein 18-like J05 N/A XM_001095051 LOC706667 Histone deacetylase 7-like J06 Mmu.14869 XM_001104451 LOC708314 Histone deacetylase 9-like J07 Mmu.13076 XM_001102628 LOC708339 Interleukin-13 receptor subunit alpha-2-like J08 N/A XM_001097165 LOC708678 Interleukin-27 subunit alpha-like J09 N/A XM_001098272 LOC709719 Interleukin-31 receptor subunit alpha-like J10 N/A XM_001098659 LOC710077 Dual specificity mitogen-activated protein kinase kinase 7-like J11 Mmu.13494 XM_001107378 LOC710294 NFAT activation molecule 1-like J12 N/A XM_001099272 LOC710605 Histone deacetylase 4-like J13 N/A XM_001099282 LOC710618 Hypothetical LOC710618 J14 N/A XM_001099782 LOC711059 Interleukin-22 receptor subunit alpha-2-like J15 Mmu.13290 XM_001100255 LOC711456 Histone deacetylase 5-like J16 N/A XM_001105109 LOC711625 Interleukin-28 receptor subunit alpha-like J17 Mmu.15846 XM_001112492 LOC711637 Regenerating islet-derived protein 3-gamma-like J18 Mmu.16382 XM_001110897 LOC712292 Interleukin-9-like J19 Mmu.9587 XR_012672 LOC712657 Receptor-type tyrosine-protein phosphatase C-like J20 Mmu.808 XM_001102454 LOC713191 CCAAT/enhancer-binding protein beta-like J21 N/A XM_001103165 LOC713715 C-C chemokine receptor-like 2-like J22 N/A XM_001107906 IL25 Interleukin-25 J23 N/A XM_001113262 LOC714491 Sperm acrosome membrane-associated protein 3-like J24 N/A XM_001113381 LOC714751 C-C motif chemokine 7-like K01 Mmu.16365 XR_092206 LOC714891 Hypothetical LOC714891 K02 N/A XM_001108593 LOC715456 Leukemia inhibitory factor-like K03 Mmu.15311 XM_001083621 LOC715757 CKLF-like MARVEL transmembrane domain-containing protein 1-like K04 N/A XM_001109808 LOC716099 C-C motif chemokine 26-like K05 Mmu.9942 XM_002805207 LOC717370 Transcriptional repressor protein YY1-like K06 N/A XM_001109725 LOC717818 C-Maf-inducing protein-like K07 N/A XM_001103121 LOC718480 Peptidoglycan recognition protein 1-like K08 Mmu.11930 XM_001117234 LOC719421 Serum amyloid P-component-like K09 Mmu.4338 XM_001114433 LOC719764 Peroxiredoxin-5, mitochondrial-like K10 N/A XM_001116431 LOC719782 FMet-Leu-Phe receptor-like K11 N/A XM_001115596 LOC720298 Embryonic growth/differentiation factor 1-like K12 Mmu.17063 XM_001117272 LOC721200 Complement component 4B (Chido blood group) K13 N/A XM_001117747 LOC721566 C-X-C motif chemokine 16-like K14 Mmu.13129 XM_001118308 LOC722115 Vascular endothelial growth factor B-like K15 N/A XM_001118911 LOC722817 Interleukin-11-like K16 Mmu.10857 NM_001047148 LTA alpha (TNF superfamily, member 1) K17 N/A XM_001114016 LTB4R Leukotriene B4 receptor K18 Mmu.11669 XM_001093552 LY75 Lymphocyte antigen 75 K19 N/A XM_001096895 LY86 Lymphocyte antigen 86 K20 Mmu.17492 NM_001130432 LY96 Lymphocyte antigen 96 K21 N/A XM_001095645 MAL Mal, T-cell differentiation protein Position UniGene GenBank Symbol Description K22 Mmu.3822 XM_001108815 MAPK8 Mitogen-activated protein kinase 8 K23 N/A XM_001092338 MEFV Mediterranean fever K24 Mmu.525 XM_001099193 MGLL Monoglyceride lipase L01 Mmu.29 NM_001032915 MIF Macrophage migration inhibitory factor (glycosylation-inhibiting factor) L02 N/A XM_001091146 MMP25 Matrix metallopeptidase 25 L03 Mmu.16484 NM_001080119 MSTN Myostatin L04 N/A XM_001102373 MUC4 Mucin 4, cell surface associated L05 Mmu.17494 NM_001130681 MYD88 Myeloid differentiation primary response gene (88) L06 Mmu.12094 XM_001090562 NAMPT Nicotinamide phosphoribosyltransferase L07 Mmu.15464 XM_001087929 NFATC1 Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 L08 N/A XM_001102777 NFATC2IP interacting protein L09 Mmu.18577 XM_001087083 NFE2L1 Nuclear factor (erythroid-derived 2)-like 1 L10 Mmu.12391 XM_001109277 NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 L11 Mmu.12443 XM_001104566 NFKB2 Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) L12 N/A XM_001111867 NFRKB Nuclear factor related to kappaB binding protein L13 Mmu.4899 NM_001037861 NK-1 NK-1 receptor L14 Mmu.13786 XM_001082994 NMI N-myc (and STAT) interactor L15 N/A XM_001108137 NODAL Nodal homolog (mouse) L16 Mmu.3443 XM_001106245 NOS2 Nitric oxide synthase 2, inducible L17 N/A XM_001085148 NOX5 NADPH oxidase, EF-hand calcium binding domain 5 L18 Mmu.12657 XM_001097126 NR3C1 Nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) L19 Mmu.12799 XM_001115025 OLR1 Oxidized low density lipoprotein (lectin-like) receptor 1 L20 Mmu.19039 XM_001110148 OSM Oncostatin M L21 N/A XM_001083745 OSMR Oncostatin M receptor L22 Mmu.12737 XM_001117681 PARP4 Poly (ADP-ribose) polymerase family, member 4 L23 Mmu.17122 XM_001083817 PCGF2 Polycomb group ring finger 2 L24 N/A XM_001096150 PDGFA Platelet-derived growth factor alpha polypeptide M01 Mmu.13134 XM_001097395 PDGFB Platelet-derived growth factor beta polypeptide M02 Mmu.12193 XM_001085049 PELI1 Pellino homolog 1 (Drosophila) M03 Mmu.13277 XM_001087641 PELI2 Pellino homolog 2 (Drosophila) M04 N/A XM_001102788 PF4 Platelet factor 4 M05 N/A XM_001102971 PF4V1 Platelet factor 4 variant 1 M06 N/A XM_001095528 PLA2G2D Phospholipase A2, group IID M07 N/A XM_001103358 PLA2G7 Phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) M08 Mmu.13587 XM_001102705 PPBP Pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) M09 N/A XM_001103106 PRG3 Proteoglycan 3 M10 Mmu.3287 NM_001047128 PRL Prolactin M11 Mmu.16109 XM_001100647 PROCR Protein C receptor, endothelial M12 N/A XM_001083022 PROK2 Prokineticin 2 M13 Mmu.3358 XM_001112976 PTAFR Platelet-activating factor receptor Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and M14 N/A XM_001107538 PTGS2 cyclooxygenase) M15 Mmu.9601 XM_001106965 PTN Pleiotrophin M16 Mmu.3612 XM_001114682 PTPRA Protein tyrosine phosphatase, receptor type, A M17 N/A XM_001103515 PTX3 Pentraxin 3, long M18 Mmu.2972 XM_001083110 PXMP2 Peroxisomal membrane protein 2, 22kDa M19 Mmu.16218 XM_001084687 RIPK2 Receptor-interacting serine-threonine kinase 2 M20 Mmu.15095 XM_001110530 S100A8 S100 calcium binding protein A8 M21 Mmu.4423 XM_001098016 S100B S100 calcium binding protein B M22 Mmu.11883 XM_001086019 SAA4 Serum amyloid A4, constitutive M23 N/A XM_001096605 SCUBE2 Signal peptide, CUB domain, EGF-like 2 M24 Mmu.1223 XM_001088209 SDCBP Syndecan binding protein (syntenin) N01 N/A XM_001094967 SELE Selectin E Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member N02 Mmu.3020 XM_001099255 SERPINA1 1 Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member N03 Mmu.3906 XM_001096947 SERPINA3 3 N04 Mmu.9527 NM_001040193 SFTPD Surfactant protein D N05 N/A XM_001115256 SIGLEC1 Sialic acid binding Ig-like lectin 1, sialoadhesin N06 Mmu.11423 XM_001095069 SIVA1 SIVA1, apoptosis-inducing factor N07 Mmu.11908 XM_001097798 SLCO1A2 Solute carrier organic anion transporter family, member 1A2 N08 N/A XM_001092510 SLURP1 Secreted LY6/PLAUR domain containing 1 N09 Mmu.12396 XM_001104595 SOCS1 Suppressor of cytokine signaling 1 N10 Mmu.3088 XM_001106151 SOCS2 Suppressor of cytokine signaling 2 N11 Mmu.12081 XM_001113221 SOCS5 Suppressor of cytokine signaling 5 N12 Mmu.225 XM_001093307 SPP1 Secreted phosphoprotein 1 N13 N/A XM_001097218 SRGAP1 Similar to SLIT-ROBO Rho GTPase activating protein 3 isoform b N14 Mmu.3514 XM_002799015 STAT1 Signal transducer and activator of transcription 1, 91kDa N15 Mmu.2929 XM_001109505 STAT3 Signal transducer and activator of transcription 3 (acute-phase response factor) N16 Mmu.13224 XM_001082561 STAT4 Signal transducer and activator of transcription 4 Position UniGene GenBank Symbol Description N17 Mmu.11577 XM_001115686 STAT6 Signal transducer and activator of transcription 6, interleukin-4 induced N18 Mmu.15644 XM_001101034 SYK Spleen tyrosine kinase N19 Mmu.13939 XM_001082367 TBX21 T-box 21 N20 Mmu.3737 XM_001087537 TFCP2 Transcription factor CP2 N21 Mmu.16252 XM_001100053 TGFB3 Transforming growth factor, beta 3 N22 Mmu.17493 NM_001130435 TIRAP Toll-interleukin 1 receptor (TIR) domain containing adaptor protein N23 Mmu.4217 NM_001130424 TLR1 Toll-like receptor 1 N24 Mmu.13239 NM_001130434 TLR10 Toll-like receptor 10 O01 Mmu.3812 NM_001130425 TLR2 Toll-like receptor 2 O02 Mmu.3813 NM_001036685 TLR3 Toll-like receptor 3 O03 Mmu.3814 NM_001037092 TLR4 Toll-like receptor 4 O04 Mmu.3815 NM_001130429 TLR5 Toll-like receptor 5 O05 Mmu.3816 NM_001130430 TLR6 Toll-like receptor 6 O06 Mmu.3817 NM_001130426 TLR7 Toll-like receptor 7 O07 Mmu.3818 NM_001130427 TLR8 Toll-like receptor 8 O08 Mmu.3819 NM_001130431 TLR9 Toll-like receptor 9 O09 Mmu.18948 XM_001103770 TMED1 Transmembrane emp24 protein transport domain containing 1 O10 Mmu.3364 NM_001047149 TNF Tumor necrosis factor O11 N/A XM_001083111 TNFAIP6 Tumor necrosis factor, alpha-induced protein 6 O12 N/A XM_001096915 TNFRSF11B Tumor necrosis factor receptor superfamily, member 11b O13 Mmu.12049 XM_001118232 TNFRSF1A Tumor necrosis factor receptor superfamily, member 1A O14 Mmu.12099 XM_001105753 TNFRSF1B Tumor necrosis factor receptor superfamily, member 1B O15 N/A XM_001118873 TNFRSF8 Tumor necrosis factor receptor superfamily, member 8 O16 N/A XM_001096166 TNFRSF9 Tumor necrosis factor receptor superfamily, member 9 O17 Mmu.1012 XM_001084768 TNFSF10 Tumor necrosis factor (ligand) superfamily, member 10 O18 Mmu.15509 XM_001092669 TNFSF11 Tumor necrosis factor (ligand) superfamily, member 11 O19 N/A XM_001082247 TNFSF13B Tumor necrosis factor (ligand) superfamily, member 13b O20 N/A XM_001089169 TNFSF14 Tumor necrosis factor (ligand) superfamily, member 14 O21 Mmu.19252 XM_001099617 TNFSF15 Tumor necrosis factor (ligand) superfamily, member 15 O22 Mmu.9528 NM_001040191 TNFSF18 Tumor necrosis factor (ligand) superfamily, member 18 O23 N/A XM_001101190 TNFSF4 Tumor necrosis factor (ligand) superfamily, member 4 O24 N/A XM_001099524 TNFSF8 Tumor necrosis factor (ligand) superfamily, member 8 P01 N/A XM_001090075 TOLLIP Toll interacting protein P02 N/A XM_001086632 TPST1 Tyrosylprotein sulfotransferase 1 P03 Mmu.15350 XM_001094589 TRAP1 TNF receptor-associated protein 1 P04 Mmu.3516 XM_001101130 TYK2 Tyrosine kinase 2 P05 Mmu.16048 XM_001112911 TYMP Thymidine phosphorylase P06 Mmu.3550 XM_001089925 VEGFA Vascular endothelial growth factor A P07 Mmu.14200 XM_001098282 VPS45 Vacuolar protein sorting 45 homolog (S. cerevisiae) P08 Mmu.3715 NM_001032947 XCL1 Chemokine (C motif) ligand 1 P09 Mmu.14970 XM_001114260 XCR1 Chemokine (C motif) receptor 1 P10 Mmu.11660 XM_001104797 YARS Tyrosyl-tRNA synthetase P11 Mmu.4974 NM_001033084 ACTB Actin, beta P12 Mmu.5037 NM_001047137 B2M Beta-2-microglobulin P13 Mmu.3145 XM_001105471 GAPDH Glyceraldehyde-3-phosphate dehydrogenase P14 Mmu.12316 XM_001097691 LOC709186 Hypoxanthine-guanine phosphoribosyltransferase-like P15 Mmu.2512 XM_001115079 RPL13A Ribosomal protein L13A P16 N/A SA_00125 QGDC Rhesus Macaque Genomic DNA Contamination P17 N/A SA_00125 QGDC Rhesus Macaque Genomic DNA Contamination P18 N/A SA_00125 QGDC Rhesus Macaque Genomic DNA Contamination P19 N/A SA_00104 RTC Reverse Transcription Control P20 N/A SA_00104 RTC Reverse Transcription Control P21 N/A SA_00104 RTC Reverse Transcription Control P22 N/A SA_00103 PPC Positive PCR Control P23 N/A SA_00103 PPC Positive PCR Control P24 N/A SA_00103 PPC Positive PCR Control Related products

For optimal performance, RT² Profiler PCR Arrays should be used together with the RT² First Strand Kit for cDNA synthesis and RT² SYBR® Green qPCR Mastermixes for PCR.

Product Contents Cat. no.

RT² First Strand Kit (12) Enzymes and reagents for cDNA synthesis 330401

RT² SYBR Green qPCR For 4 x 384 assays in 384-well plates; suitable for 330501 Mastermix (8)* use with real-time cyclers that do not require a reference dye, including: Bio-Rad model CFX384; Roche LightCycler 480 (384-well); all other cyclers

RT² SYBR Green ROX™ qPCR For 4 x 384 assays in 384-well plates; suitable for 330521 Mastermix (8)* use with the following real-time cyclers: Applied Biosystems models 7900HT, ViiA 7 (384-well blocks)

RT² SYBR Green Fluor qPCR For 4 x 384 assays in 384-well plates; suitable for 330511 Mastermix (8)* use with the following real-time cyclers: Bio-Rad models iCycler®, iQ™5, MyiQ™, MyiQ2

* Larger sizes available; please inquire.

RT² Profiler PCR Array products are intended for molecular biology applications. These products are not intended for the diagnosis, prevention, or treatment of a disease.

For up-to-date licensing information and product-specific disclaimers, see the respective QIAGEN kit handbook or user manual. QIAGEN kit handbooks and user manuals are available at www.qiagen. com or can be requested from QIAGEN Technical Services or your local distributor.

Trademarks: QIAGEN®(QIAGEN Group); Applied Biosystems®, ViiA™, ROX™ (Applera Corporation or its subsidiaries); Bio-Rad®, CFX384™, iQ™, MyiQ™. iCycler® (Bio-Rad Laboratories,Inc.); Roche®, LightCycler® (Roche Group); SYBR®(Molecular Probes, Inc.). 1067687 03/2011 © 2011 QIAGEN, all rights reserved.

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