Anti-CENPC (aa 394-424) polyclonal antibody (DPABH-21882) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description Component of the CENPA-NAC (-associated) complex, a complex that plays a central role in assembly of , mitotic progression and segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into . CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the code in these regions.

Immunogen Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 394-424 of Human CENPC (Accessions: Q03188, NP_001803.2).

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Purification Immunogen affinity purified

Conjugate Unconjugated

Applications WB

Format Liquid

Size 400 μl

Buffer Constituent: 99% PBS

Preservative 0.09% Sodium Azide

Storage Store at 4°C (up to 6 months). For long term storage store at -20°C

GENE INFORMATION

Gene Name CENPC C [ Homo sapiens ]

Official Symbol CENPC

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Synonyms CENPC; centromere protein C; MIF2; hcp-4; CENP-C; CENPC1; CENP-C 1; centromere protein C 1; centromere autoantigen C; centromere autoantigen C1; interphase centromere complex protein 7;

Entrez Gene ID 1060

Protein Refseq NP_001803.2

UniProt ID Q03188

Pathway Cell Cycle; M Phase; Mitotic Metaphase and ; Resolution of Sister Cohesion.

Function DNA binding; centromeric DNA binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved