Anti-CENPC (aa 394-424) polyclonal antibody (DPABH-21882) This product is for research use only and is not intended for diagnostic use.
PRODUCT INFORMATION
Antigen Description Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.
Immunogen Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 394-424 of Human CENPC (Accessions: Q03188, NP_001803.2).
Isotype IgG
Source/Host Rabbit
Species Reactivity Human
Purification Immunogen affinity purified
Conjugate Unconjugated
Applications WB
Format Liquid
Size 400 μl
Buffer Constituent: 99% PBS
Preservative 0.09% Sodium Azide
Storage Store at 4°C (up to 6 months). For long term storage store at -20°C
GENE INFORMATION
Gene Name CENPC centromere protein C [ Homo sapiens ]
Official Symbol CENPC
45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]
Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Synonyms CENPC; centromere protein C; MIF2; hcp-4; CENP-C; CENPC1; CENP-C 1; centromere protein C 1; centromere autoantigen C; centromere autoantigen C1; interphase centromere complex protein 7;
Entrez Gene ID 1060
Protein Refseq NP_001803.2
UniProt ID Q03188
Pathway Cell Cycle; M Phase; Mitotic Metaphase and Anaphase; Resolution of Sister Chromatid Cohesion.
Function DNA binding; centromeric DNA binding;
45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]
Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved