Curriculum Vitae, HC Pape MD, FACS
CURRICULUM VITAE
BIOGRAPHICAL
Hans-Christoph Pape, MD, FACS
Chairman Department of Trauma Surgery University Hospital Zurich Rämistrasse 100 8091 Zurich – Switzerland
Mail: [email protected] www.traumatologie.usz.ch www.usz.ch
Previous leading positions
02.2017 – present Department auf Trauma / Professor & Chariman Trauma Surgery University Hospital Zurich Switzerland
02/2009 - 01/2017 RWTH Professor & Chairman Medical Center Aachen Trauma & Aachen, Germany Reconstructive Surg.
10/2005 – 01/2009 University of Pittsburgh Chief, Ortho Trauma Medical Center Department Pittsburgh, PA of Orthopaedic Surgery
01/2003-09/2005 Hanover Medical School, Vice-Chairman, Germany Department of Ortho/Trauma Surgery
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APPOINTMENTS and POSITIONS
02/2009 – 01/2017 Univerity of Aachen Chairman Medical Center W.Pauwels Professor Aachen, Germany Dept. of Orthopaedic Surgery
10/2005 – 02/2009 University of Pittsburgh Division Chief of Medical Center Traumatology, Dept Pittsburgh, PA of Orthopaedic Surgery
10/2005 – 1/2009 University of Pittsburgh Associate Professor Medical Center Traumatology, Dept Pittsburgh, PA of Orthopaedic Surgery
01/2005 University of Texas, Visiting Professor El Paso, TX
08/1996-09/2005 Hanover Medical School, Attending Germany Orthopaedic and Trauma Surgeon
01/2001-09/2005 Hanover Medical School, Chair “Polytrauma” Germany Study Group
02/2000-09/2005 Hanover Medical School, Full Professor of Germany Trauma Surgery
03/2004 University of Alabama, Visiting Professor Birmingham, AL
04/2003 Harvard Med. School, Visiting Professor Mass. General Hospital, Boston, MA
06/1996-01/2000 Hanover Medical School, Assistant Professor of Germany Trauma Surgery
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EDUCATION and TRAINING
10/81-6/88 Hannover Medical School, Germany
7/84-8/84 Clerkship, Horton Gen. Hospital, Banbury (GB)
8/85-4/86 Scholarship (German Academic Exchange Service, DAAD) Vanderbilt University, Nashville TN, Harvard University, Boston MA
5/86-7/86 Research Fellow Mass. General Hospital, Harvard University, Boston, MA (Prof. Zervas)
1/88-3/88 Combined Research Program Hannover Medical School / Mass. General Hospital, Harvard University, Boston MA, Department of Neurology
12/88 Internship, University of Ulm, Germany
12/89-11/95 Residency, Dept. of Trauma Surgery, Hannover Medical School
CERTIFICATION and LICENSURE
2015 – present German Society of Orthopaedic and Scientific Committee Trauma Surgery (DDOU Meeting
SIGOT Leader Trauma Team
OTA Membership committee, Internation Committee
2005 - present German Combined Orthopaedic Board Certified and Trauma Surgery Board Orthopaedic and Trauma Surgery
2000 - present European board of surgeons EBSQ exam
1996 - present German Board of Orthopaedic Board Certified and Trauma Surgery Orthopaedic and Trauma Surgeon
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1995 - present German Board of Surgery Board Certified Surgeon
License: Commonwealth of Pennsylvania, unrestricted, No. MD 427157
HONORS
Award Dieffenbach-Büste of the German Society of Orthopaedic 2017 and Trauma Surgery. The Dieffenbach award donated in 1982 as an honorable award for the scientific merits of Trauma.
British Medical Society Award: Best Book in 2015 2015
Kappa Delta Award, American Academy of Orthopaedic Surgeons 2008 Effects of Changing Strategies of Fracture Fixation on Immunologic Changes and Systemic Complications after Multiple Trauma
Swiss AO Foundation Annual Award , Berne, Switzerland 2006 Early assessment of degree of hemorrhage in patients with blunt trauma
Novartis Prize 2005
Injury Award, British Trauma Society 2004 Damage control surgery in patients in extremis with unstable pelvic fracture
Injury Award, British Trauma Society 2004 Damage control surgery in patients in extremis with unstable pelvic fracture
Travel Award, Shock Society, Halifax, CA 2004 Genetic predisposition for a compromised immune system after trauma
Earle Conwell Lecture Award in Orthopaedic Trauma 2004 Trauma care in Germany
Basic Science Research Award, Greek Trauma Society 2003 Assessment of endothelial permeability following femoral instrumentation in a sheep model: what is the effect of lung contusion and reaming
Injury Prize, British Trauma Society (BTS) 2003 The effect of RIA reaming on lung function in a sheep model
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Best European Paper Presentation, British Trauma Society (BTS) 2002 Early evaluation of blunt chest trauma: development of a scoring system for early decision making
Best Scientific Paper Presentation, European Trauma Society (ETS) 2002 Development of a CT-independent scoring system for grading chest trauma
Günther Schlag Award, European Trauma Society (ETS) 2002 Immunomodulation by DHEA-medication in multiple trauma situations: a second hit model
Canizaro Award, American Association for the Surgery of Trauma (AAST) 2000 Major secondary surgery in blunt trauma patients and perioperative cytokine liberation: determination of the clinical relevance of biochemical markers
Travel Award International Shock Society 2000
Effects of the secretion of metabolic regulating hormones (leptin) and posttraumatic complications in polytrauma
Hans Liniger Award, German Trauma Society (DGU) 1996 Pulmonary complications after intramedullary stabilization of the femoral shaft
Unimed Award 1998 Surgical burden of IM nailing
MEMBERSHIPS in PROFESSIONAL and SCIENTIFIC SOCIETIES
2008 American Orthopaedic Association
Since 2007 American Academy of Orthopaedic Surgeons
Since 2000 AO/ASIF Alumni
Since 1999 Founding Member “Shock Research Group” of the German interdisciplinary ICU society (DIVI)
Since 1999 Founding Member “Multi Organ Failure Research Group” of the German interdisciplinary ICU society (DIVI)
Since 1999 Founding Member “Polytrauma Research Group” of the German interdisciplinary ICU society (DIVI)
Since 1999 Orthopaedic Trauma Association (OTA)
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Since 1999 North American Shock Society
Since 1998 American Association for the Surgery of Trauma (AAST)
Since 1998 German Interdisciplinary ICU Society (DIVI)
Since 1997 European Shock Society
Since 1995 Rescue Physicians in Northern Germany (AGNN)
Since 1994 German Society of Surgery (DGC)
Since 1993 Founding Member German Polytrauma Registry
Since 1990 German Trauma Society (DGU)
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EDITOR IN CHIEF Open Access Emergency Medicine
SECTION EDITOR Injury – Editor: Reviews European Journal of Trauma – Section Editor: Polytrauma
EDITORIAL BOARD MEMBER Operative Techniques in Orthopaedics Journal of Trauma, Infection and Critical Care Patient Safety in Surgery
PEER REVIEWER SCIENTIFIC JOURNALS Journal of Orthopaedic Trauma Journal of Trauma, Infection and Critical Care Clinical Orthopedics and Related Research Journal of Bone and Joint Surgery (American) Journal of Bone and Joint Surgery (British) Injury Unfallchirurg Chirurg
GRANT REVIEWER German Research Society, Deutsche Forschungsgemeinschaft (DFG)
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Books Pape HC. Systemische Auswirkungen der Marknagelung. Hefte zu Dr Unfallchirurg, 264, 1997 Adams, H.A., G. Baumann, I. Cascorbi, C. Ebener, M. Emmel, S. Geiger, U. Janssens, U. Klima, H.J. Klippe, W.T. Knoefel, G. Marx, U. Müller-Werdan, HC Pape, J. Piek, H. Prange, D. Roesner, B. Roth, T. Schürholz, T. Standl, W. Teske, P.M. Vogt, G.S. Wer¬ner, J. Windolf, R. Zander, H.R. Zerkowski: Empfehlungen zur Diagnostik und Therapie der Schockformen der IAG Schock der DIVI. Köln: Deutscher Ärzte-Verlag 2005. Practical procedures in Orthopaedic trauma Surgery Cambridge University Press, Eds.: P. Giannoudis and H.-C. Pape 2005
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Damage Control in the polytrauma patient Springer Verlag, Eds.: HC. Pape, A.Peitzman, B.Schwab, P.Giannoudis 2009
Autologous techniques to fill bone defects for acute fractures and nonunions Orthopaedic Clinics of North America, Eds.: HC. Pape, T.Weber 2010
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The Poly-Traumatized Patient with Fractures Springer Verlag, Eds.: HC. Pape, R. Sanders, J. Borrelli 2011
The Poly-Traumatized Patient with Fractures (2nd edition) Springer Verlag, Eds.: HC. Pape, R. Sanders, J. Borrelli 2015
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PUBLICATIONS
PUBLICATIONS IN PEER REVIEW JOURNALS Lead Author
1. Pape HC, Dwenger A, Regel G, Jonas M, Krumm K, Schweitzer G, Sturm JA. Hat die Lungenkontusion und allgemeine Verletzungsschwere einen Einfluss auf die Lunge nach Oberschenkelmarknagelung? - Ein tierexperimentelles Modell. Unfallchirurg 1991 Aug;94(8):381-9.
2. Pape HC, Regel G, Sturm JA, Tscherne H. Ist das posttraumatische Nierenversagen therapeutisch zu beeinflussen? Unfallchirurg 1992 Sep;95(9):419-25.
3. Pape HC, Regel G, Dwenger A, Krettek C, Mehler D, Sturm JA, Tscherne H. Effekte unterschiedlicher intramedullärer Stabilisierungsverfahren des Femur auf die Lungenfunktion bei Polytrauma. Unfallchirurg 1992 Dec;95(12):634-40.
4. Pape HC, Dwenger A, Regel G, Schweitzer G, Jonas M, Remmers D, Krumm K, Neumann K, Sturm JA, Tscherne H. Pulmonary damage after intramedullary femoral nailing in traumatized sheep - is there an effect from different nailing methods? J Trauma 1992 Oct;33(4):574-81.
5. Pape HC, Dwenger A, Regel G, Schweitzer G, Remmers D, Pape D, Sturm JA. Haemorrhagic Shock, endotoxin and complement activation induce late organ failure in sheep. Theoretical Surgery 1993; 8(1): 21-28.
6. Pape HC, Auf`m`Kolck M, Paffrath T, Regel G, Sturm JA, Tscherne H. Primary intramedullary femur fixation in multiple trauma patients with associated lung contusion - a cause of posttraumatic ARDS? J Trauma 1993; 34(4): 540-548.
7. Pape HC, Regel G, Dwenger A, Krumm K, Schweitzer G, Krettek C, Sturm JA, Tscherne H. Influences of different methods of intramedullary femoral nailing on lung function in patients with multiple trauma. J Trauma 1993; 35(5): 709-715.
8. Pape HC, Regel G, Dwenger A, Sturm JA, Tscherne H. Influence of thoracic trauma and primary femoral intramedullary nailing on the incidence of ARDS in multiple trauma patients. Injury 1993; 24(3): 82-103.
9. Pape HC, Regel G, Borgmann W, Sturm JA, Tscherne H. Der Einfluß des kontinuierlichen axialen Lagewechsels bei der Behandlung des posttraumatischen Lungenversagens. Unfallchirurg 1993; 19(6): 329-338.
10. Pape HC, Dwenger A, Regel G, Auf`m`Kolck M, Gollub F, Wisner D, Sturm JA, Tscherne H. Increased gut permeability after multiple trauma. British J Surgery 1994; 81: 850-852.
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11. Pape HC, Regel G, Borgmann W, Sturm JA, Tscherne H. The effect of kinetic positioning on lung function and pulmonary hemodynamics in posttraumatic ARDS - a clinical study. Injury 1994; 25(1): 51-57.
12. Pape HC, Regel G, Grotz M, Borgman W, Mehler D, Tscherne H. Kinetische Lagerung bei posttraumatischen Lungenversagen – Pathogenetische Gesichtspunkte und Möglichkeiten des Monitoring. Anästhesiologie und Intensivmedizin 1994; 35: 89-96.
13. Pape HC, Dwenger A, Regel G, Schweitzer G, Remmers D, Pape D, Sturm JA. Pulmonary damage after recurrent administration of endotoxin and zymosan - activated plasma - a sheep model. Theoretical Surgery 1994; 9: 82-89.
14. Pape HC, Kleemann W, Regel G, Goris RJA, Tscherne H. Organ response after severe trauma - a comparison between clinical and morphological patterns. J European Urgency and Resuscitation 1994; 7: 13-20.
15. Pape HC., Remmers D, Kleemann W, Goris, JA, Regel G, Tscherne H. Posttraumatic multiple organ failure - a report on clinical and autopsy findings. Shock 1994; 1: 228-234.
16. Pape HC, Dwenger A, Grotz M, Kaever V, Negatsch R, Kleemann W, Regel G., Sturm JA, Tscherne H. Does the reamer type influence the degree of lung dysfunction after femoral nailing following severe trauma? - An animal study. J Orthopaedic Trauma 1994; 8(4): 300-309.
17. Pape HC, Remmers D, Regel G, Tscherne H. Der Einfluß des Verletzungsmusters und des Verletzungsschweregrades auf posttraumatische pulmonale Komplikationen nach intramedullärer Stabilisierung langer Röhrenknochen. Der Orthopäde 1995; 24: 164-172.
18. Pape HC, Bosch U, Lobenhoffer P, Konrad B, Maghsudi M, Tscherne H. Die Kapselplastik nach Rockwood bei Schulterinstabilität- eine klinische Nachuntersuchung. Unfallchirurg 1995; 98: 289-295.
19. Pape HC, Hoffmann M, Zwipp H, Tscherne H. Chronic diaphyseal osteomyelitis of long bones refractory to conventional therapy - benefits and risks of reaming of the femoral medullary cavity. European J Orthopaedic Surgery and Traumatology 1995; 5: 53-58.
20. Pape HC, Hoffmann M, Maschek H, Zwipp H, Tscherne H. Chronische therapierefraktäre Osteomyelitis langer Röhrenknochen - Möglichkeiten und Risiken der Markraumbohrung. Unfallchirurg 1995; 98: 139-144.
21. Pape HC, Dwenger A, Regel G, Remmers D, Tscherne H. Intramedullary femoral nailing in sheep: Does severe injury predispose to pulmonary dysfunction? European J Surgery 1995; 151: 163-171.
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22. Pape HC, Regel G, Dwenger A, Grotz M, Remmers D, Tscherne H. The risk of early intramedullary nailing of long bone fractures in multiply traumatized patients. Complications in Orthopaedics 1995; 10(1): 15-23.
23. Pape HC. Operationstrauma des unaufgebohrten Oberschenkelmarknagels aus experimenteller und klinischer Sicht. Hefte zu "Unfallheilkunde" 1996; 253: 191- 196.
24. Pape HC, Regel G, Tscherne H. Local and systemic effects of fat embolization after intramedullary reaming and its influence by cofactors. Techniques in Orthopaedics 1996; 11(1): 2-13.
25. Pape HC, Regel G, Tscherne H. Controversies regarding early musculoskeletal management in the multiple trauma patient. Current Opinion in Critical Care 1996; 2: 295-303.
26. Pape HC, Krettek C, Friedrich A, Tscherne H. Proximale hüftgelenksnahe Frakturen im Kindesalter - Therapie, Verlauf und Komplikationen. Sozialpädiatrie und Kinderärztliche Praxis 1996; 18(1): 32-39.
27. Pape HC, Krettek C, Maschek HJ, Regel G, Tscherne H. Fatal pulmonary embolization after reaming of the femoral medullary cavity in sclerosing osteomyelitis. J Orthopaedic Trauma 1996; 10(6): 429-432.
28. Pape HC, Remmers D, Regel G, Tscherne H. Evaluation thorakaler Verletzungsschwere und ihre Bedeutung für den posttraumatischen Verlauf - eine retrospektive Untersuchung an 1326 Patienten. Langenbeck`s Arch Chir. Suppl. II: 1997; 1270-1273.
29. Pape HC, Regel G. Das schwere Thoraxtrauma - Entscheidungshilfen bei der Diagnostik und Therapie. Journal für Anästhesie und Intensivmedizin 1997; 97-100.
30. Pape HC, Weinberg A, Graf B, Reilmann H, Tscherne H, Regel G. Kontinuierlicher axialer Lagerungswechsel bei posttraumatischem Lungenversagen – prophylaktisch oder therapeutisch indiziert? Anästhesiologie Intens. Notfallmed. Schmerzther. 1997; 32: 245-249.
31. Pape HC, Remmers D, Regel G, Weinberg A, Graf B, Reilmann H, Tscherne H. Is early kinetic positioning beneficial for pulmonary function in multiple trauma patients? Injury 1998 Apr;29(3):219-25.
32. Pape HC, Remmers D, Grotz M, Dwenger A, Vake R, Wisner D, Tscherne H. Multiple organ failure (MOF) after severe trauma - a sheep model. Intensive Care Medicine 1998; 24(6): 590-598.
33. Pape HC, Bartels M, Pohlemann T, Werner T, Tscherne H. Coagulatory response after femoral instrumentation following severe trauma in sheep. J Trauma 1998; 45(4): 720-728.
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34. Pape HC, Remmers D, Schedel I, Glinski S, Dahlweit M, Oberbeck R, Tscherne H. Levels of antibodies to endotoxin and cytokine release in patients with severe trauma. J Trauma 1998; 46(5): 907-913.
35. Pape HC. Management of traumatic shock - results of the German Trauma Registry. Acta Anästhesiologica Scandinavica 1998; 42(112): 172-174.
36. Pape HC, Stalp M, Dahlweid M, Regel G, Tscherne H. Welche primäre Operationsdauer ist hinsichtlich eines "Borderline-Zustand" polytraumatisierter Patienten vertretbar? Unfallchirurg 1999; 102(11): 861-869.
37. Pape HC, Remmers D, Grotz M, Kotzerke J, Glinski S, van Griensven M., Dahlweid M., Sznidar S., Tscherne H. Reticuloendothelial system activity and organ failure in multiply injured patients. Archives of Surgery 1999; 134: 421-427.
38. Pape HC, Bund M, Meier R, Piepenbrock S, Tscherne H. Pulmonary dysfunction following bilateral femoral nailing: A case report. Intensive Care Medicine 1999; 25(5): 547-548.
39. Pape HC, Meier R, Sturm JA. Physiologic changes following infusion of colloids or crystalloids. J Intensive Care 1999; 47-53.
40. Pape HC, Krettek C, Friedrich A, Pohlemann T, Simon R, Tscherne H. Long term outcome in children with fractures of the proximal femur after high energy trauma. J Trauma 1999; 46(1): 58-64.
41. Pape HC, Stalp M, van Griensven M, Weinberg A, Dahlweit M, Grotz M, Tscherne H. Optimaler Zeitpunkt der Sekundäroperation bei Polytrauma. Der Chirurg 1999; 70(11): 1287-1293.
42. Pape HC, Nickel E, Dahlweid F, Oberbeck R, Tscherne H, Regel G. Das Zusammenspiel des stationären und mobilen Immunsystems im Rahmen des septiformen Traumaverlaufes. Journal für Anästhesie und Intensivmedizin 1999; 117-122.
43. Pape HC, Oestern HJ, Leenen L, Yates DW, Stalp M, Grimme K, Tscherne H, Krettek C, the German Polytrauma Study Group. Documentation of blunt trauma in Europe. European J Trauma 2000; 26(5): 233-247.
44. Pape HC, Barthels M, van Griensven M, Krettek C, Das Gupta R, Tscherne H. Biochemical changes following trauma and skeletal surgery of the lower extremity – quantification of the operative burden. Critical Care Medicine 2000; 28(10): 3441- 3448. 45. Pape HC, Remmers D, Rice J, Ebisch M, Krettek C, Tscherne H. Appraisal of early evaluation of blunt chest trauma: Development of a standardized scoring system for initial clinical decision making. J Trauma 2000; 49(3): 496-504.
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46. Pape HC, Rice J, Wolfram K, Gänsslen A, Pohlemann T, Krettek C. Hip dislocation in patients with multiple injuries. Clinical Orthopaedics and Related Research 2000; 377: 99-105. 47. Pape HC, Lehmann U, van Griensven M, von Glinski S, Krettek C. Heterotopic ossifications in patients after severe blunt trauma with and without head trauma: Incidence and patterns of distribution. J Orthopaedic Trauma 2001;15(4): 229-237. 48. Pape HC, van Griensven M, Rice J, Hildebrand F, Winny M, Krettek C. Major secondary surgery in blunt trauma patients and perioperative cytokine liberation: Determination of the relevance of biochemical markers. J Trauma 2001; 50(6): 989-1000. 49. Pape HC. Early definitive femoral fracture fixation in polytrauma: advantages vs systemic effects. Current Orthopaedics 2001; 15: 184-191.
50. Pape HC. Wann kann/muss/darf nicht primär definitiv versorgt werden bei SHT- Thoraxtrauma-kritischem (Borderline) Zustand? Journal für Anästhesie und Intensivmedizin 2002; 185-192.
51. Pape HC, Giannoudis P, Grimme K, van Griensven M, Krettek C. Effects of intramedullary femoral fracture fixation: What is the impact of experimental studies in regards to the clinical knowledge? Shock 2002; 18(4):291-300. 52. Pape HC, Hildebrand F, Pertschy S, Zelle B, Garapati R, Grimme K, Krettek C. Changes in the management of femoral shaft fractures in polytrauma patients: From early total care to damage control orthopaedic surgery. J Trauma 2002; 53(3): 452- 462. 53. Pape HC, Giannoudis P, Krettek C. The timing of fracture treatment in polytrauma patients – relevance of damage control orthopaedic surgery. Amer J Surgery 2002;183: 622-629. 54. Pape HC, Krettek C. Leitthema: "Frakturversorgung der Schwerverletzten – Einfluss des Prinzips der "verletzungsadaptierten Behandlungsstrategie." Unfallchirurg 2003; 106: 87-96. 55. Pape HC, Grotz M, Schwermann T, Ruchholtz S, Lefering R, Rieger M, Tröger M, Graf v. d. Schulenburg JM, Krettek C, AG Polytrauma der DGU. Entwicklung eines Modells zur Berechnung der Kosten der Versorgung Schwerverletzter - eine Initiative des Traumaregisters der DGU. Unfallchirurg 2003; 106: 348-357. 56. Pape HC, Grimme K, van Griensven M, Scott A, Giannoudis P, Morley M, Roise O, Ellingsen E, Hildebrand F, Wiese B, Krettek C. Impact of intramedullary instrumentation versus damage control for femoral fractures on immunoinflammatory parameters in a prospective randomized analysis. J Trauma 2003; 55(1): 7-13. 57. Pape HC, Krettek C. Verletzungsadaptierte Behandlungsstrategie. Unfallchirurg 2003; 106: 85-86.
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58. Pape HC, Mahlke L, Schaefer O, Krettek C. Gedanken zu ökonomischen Aspekten der Behandlung Schwerverletzter unter den Bedingungen der “diagnoses related groups” (DRG) – eine Initiative des Berufsstän-dischen Ausschusses der DGU. Unfallchirurg 2003; 106:869-873.
59. Pape HC, Zelle B, Sitnik J, Gänsslen A, Krettek C. Iliumosteotomie bei Hüftgelenksluxationsfraktur mit posterior-inferiorer Gelenkfragmentdislokation. Unfallchirurg 2004; 107(3):239-43.
60. Pape HC, Marsh S, Morley JR, Krettek C, Giannoudis PV. Current concepts in the development of heterotopic ossification. J-Bone-Joint-Surg-Br 2004; 86(6):783-7.
61. Pape HC, Hildebrand F, Pertschy S, Zelle B, Garapati R, Grimme K, Krettek C. Changes in the management of femoral shaft fractures in polytrauma patients: from early total care to damage control orthopedic surgery. J-Orthop-Trauma Suppl 2004; 18(8): S13-22.
62. Pape HC, Schmidt RE, Rice J, van Griensven M, Das Gupta R, Krettek C, Tscherne H. Biochemical changes after trauma and skeletal surgery of the lower extremity: quantification of the operative burden. J-Orthop-Trauma Suppl 2004; 18(8): S24- 33.
63. Pape HC, Giannoudis PV, Krettek C, Trentz O. Timing of Fixation of Major Fractures in Blunt Polytrauma: Role of Conventional Indicators in Clinical Decision Making. J Orthop Trauma 2005 Sep;19(8):551-562.
64. Pape HC, Hildebrand F, Krettek C, Green J, Giannoudis PV. Experimental background-review of animal studies. Injury 2006 Oct;37 Suppl 4:S25-38.
65. Pape HC, Zelle BA, Hildebrand F, Giannoudis PV, Krettek C, van Griensven M. Reamed femoral nailing in sheep: does irrigation and aspiration of intramedullary contents alter the systemic response? Bone Joint Surg Am. 2005 Nov; 87(11): 2515- 22.
66. Pape HC. Immediate fracture fixation--which method? Comments on the John Border Memorial Lecture, Ottawa, 2005. J Orthop Trauma 2006 May;20(5):341-50.
67. Pape HC, Erhardtsen E, Meyer C, Leppäniemi AK. Recombinant Factor VIIa for Life-Threatening Hemorrhage in Trauma Patients: Review of the Literature. Eur J Trauma 2006;32:439–48.
68. Pape HC, Zelle B, Lohse R, Hildebrand F, Krettek C, Panzica M, Duhme V, Sittaro NA. Evaluation and outcome of patients after polytrauma-Can patients be recruited for long-term follow-up? Injury 2006 Dec;37(12):1197-203.
69. Pape HC, Rixen D, Morley J, Husebye EE, Mueller M, Dumont C, Gruner A, Oestern HJ, Bayeff-Filoff M, Garving C, Pardini D, van Griensven M, Krettek C, Giannoudis P; EPOFF Study Group. Impact of the method of initial stabilization for
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femoral shaft fractures in patients with multiple injuries at risk for complications (borderline patients). Ann Surg. 2007 Sep; 246(3):491-9; discussion 499-501.
70. Pape HC, Giannoudis P. The biological and physiological effects of intramedullary reaming. J Bone Joint Surg Br. 2007 Nov;89(11):1421-6.
71. Pape HC, Tsukamoto T, Kobbe P, Tarkin I, Katsoulis S, Peitzman A. Assessment of the clinical course with inflammatory parameters. Injury 2007 Dec;38(12):1358- 64.
72. Pape HC. Effects of changing strategies of fracture fixation on immunologic changes and systemic complications after multiple trauma: Damage control orthopedic surgery. J Orthop Res. 2008 Jun 3. [Epub ahead of print]
73. Pape HC, Webb LX. History of open wound and fracture treatment. Journal of Orthopaedic Trauma 2008 Nov.-Dec.;22(10 Suppl):S133-4.
74. Pape HC, Griensven MV, Hildebrand FF, Tzioupis CT, Sommer KL, Kerettek CC, Giannoudis PV. Epoff Study group. Systemic inflammatory response after extremity or truncal fracture operations. J Trauma 2008 Dec;65(6);1379-84.
75. Pape HC, Pfeifer R. Restricted duty hours for surgeons and impact on residents quality of life, education, and patient care: a literature review. Patient Saf Surg. 2009 Feb 20;3(1):3.
76. Pape HC, Archdeacon MT. Introduction: Biology and new technical trends in intramedullary nailing of the femur. J Orthop Trauma 2009 May-Jun;23(5 Suppl):S Impact 1.12
77. Pape HC, Tarkin IS. Intraoperative reduction techniques for difficult femoral fractures. J Orthop Trauma 2009 May-Jun;23(5 Suppl):S6-11 Impact 0.94
78. Pape HC, Tornetta P 3rd, Tarkin I, Tzioupis C, Sabeson V, Olson SA. Timing of fracture fixation in multitrauma patients: the role of early total care and damage control surgery. J Am Acad Orthop Surg. 2009 Sep;17(9):541-9 Impact 1.4
79. Pape HC, Marcucio R, Humphrey C, Colnot C, Knobe M, Harvey EJ. Trauma- induced inflammation and fracture healing. J Orthop Trauma 2010 Sep;24(9):522- 5. Impact 1.8
80. Pape HC, Bottlang M (2011) Flexible fixation with locking plates. J Orthop Trauma 25 Suppl 1:S1-3 (IF 2,135) 2012 Impact 1.8
81. Pape HC, Lefering R. Grading of injury severity - What should be the prerequisites to separate multiply injured patients from those in critical condition and polytrauma? Injury 2013 Jan 2. [Epub ahead of print]
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82. Pape HC, Lefering R. Grading of injury severity - What should be the prerequisites to separate multiply injured patients from those in critical condition and polytrauma? Injury 2013;44(2): 157-8 (Impact(2012)=2.174)
83. Pape HC, Vrahas MS. Symposium: Tscherne Festschrift: editorial comment. Clin Orthop Relat Res. 2013;471(9): 2751-2 (Impact(2012)=2.787)
84. Pape HC, Lefering R., Butcher N., Peitzman A. Leenen L., Marzi I., Lichte P. Josten C., Bouillon B Schmucker U., Stahel P.F., Giannoudis P., Balogh ZJ. The Berlin Definition of Polytrauma - Results from an International Consensus Process and a data base analysis. J. Trauma, Infection and Crit.Care, in press 2014
85. Pape HC, Friess T, Liener U, Ruchholtz S, Schmucker U, Sturm JA, Buecking G, Riem G, Hartwig E. Development of geriatric trauma centers- An effort by the German Society of Trauma and Orthopaedics. Injury 2014 Oct;45(10):1513-5.
86. Pape HC, Lefering R, Butcher N, Peitzman A, Leenen L, Marzi I, Lichte P, Josten C, Bouillon B, Schmucker U, Stahel P, Giannoudis P, Balogh Z. The definition of polytrauma revisited: An international consensus process and proposal of the new 'Berlin definition'. J Trauma Acute Care Surg. 2014 Nov;77(5):780-786.
87. Pape HC, Pfeifer R. Safe definitive orthopaedic surgery (SDS): repeated assessment for tapered application of Early Definitive Care and Damage Control?: an inclusive view of recent advances in polytrauma management. Injury 2015 Jan;46(1):1-3.
88. Pape HC, Schemmann U, Foerster J, Knobe M. The 'Aachen Falls Prevention Scale' - development of a tool for self-assessment of elderly patients at risk for ground level falls. Patient Saf Surg. 2015 Feb 14;9:7.
89. Pape HC, Dougherty PJ. CORR® Curriculum--Orthopaedic Education: The Evolution of Orthopaedic Surgery Education in Germany. Clin Orthop Relat Res. 2015 Aug;473(8):2464-8.
90. Pape HC, Champion HR. Patient assessment in polytrauma: Current trends rely on multiple parameters to improve the prediction of complications and mortality. Injury 2015 Oct;46(10):1875-7
91. Pape HC, Andruszkow H, Pfeifer R, Hildebrand F, Barkatali BM. Options and Hazards of the EAC protocol. Injury. 2016 Apr;47(4):787-91. doi:10.1016/j.injury.2016.03.020. No abstract available.
92. Pape HC, Barkatali, Andruszkow. Issues regarding patient assessment scores that focus on acid base changes in fracture pstients.J Trauma Acute Care Surg. 2016 May;80(5):838. doi: 10.1097/TA.0000000000000990. No abstract available.
18 Curriculum Vitae, HC Pape MD, FACS
93. Pape HC, Bischoff-Ferrari HA. How can we influence the incidence of secondary fragility fractures? A review on current approaches. Injury. 2017 Sep 1. pii: S0020- 1383(17)30553-3. doi: 10.1016/j.injury.2017.08.034 [Epub ahead of print].
19 Curriculum Vitae, HC Pape MD, FACS
Co-author
1. Dwenger A, Beychok C, Schweitzer G, Pape HC. Pattern and functions (chemiluminescence, enzyme secretion) of alveolar macrophages and granulocytes in the posttraumatic course. Fresenius Journal for Analytical Chemistry 1990; 337: 86-87.
2. Regel G, Sturm JA, Pape HC, Gratz KE, Tscherne H. Das Multiorganversagen - Ausdruck eines generalisierten Zellschadens aller Organe nach schwerem Trauma. Unfallchirurg 1991; 94: 487-49.
3. Dwenger A, Schweitzer G, Pape HC, Lehmann U. Determinations of human neutrophil elastase in bronchoalveolar lavage fluid: Homogeneous immunoactivation versus heterogeneous enzyme immunoassay. Eur. J. Clin. Chem. Clin. Biochem. 1992, 30: 785-78.
4. Regel G, Lobenhoffer P, Lehmann U, Pape HC, Pohlemann T, Tscherne H. Ergebnisse in der Behandlung polytraumatisierter - eine vergleichende Analyse von 3406 Fällen zwischen 1972 und 1991. Unfallchirurg 1993; 96: 350-362.
5. Krettek C, Schandelmaier P, Pape HC, Tscherne H. Moderne Osteosyntheseverfahren zur verbesserten Schonung der Fragmentdurch-blutung: Marknagelung. Langenbecks Archiv für Chirurgie Suppl.: 1991; 882-892.
6. Dwenger A, Pape HC, Bantel K, Schweitzer G, Krumm K, Grotz M, Lücken B, Funck M, Tscherne H. Ascorbic acid reduces the endotoxin induced lung injury in awake sheep. European J Clinical Investigation 1994; 24: 229-235.
7. Regel G, Pape HC, Pohlemann T, Seekamp A, Bosch U, Tscherne H. Scores als Entscheidungshilfe. Unfallchirurg 1994; 97: 211-216.
8. Regel G, Lobenhoffer P, Grotz M, Pape HC, Lehmann U, Tscherne H. Treatment results of patients with multiple trauma: An analysis of 3406 cases treated between 1972 and 1991 in a German level 1 trauma center. J Trauma 1995; 38: 70- 78.
9. Dwenger A, Remmers D, Grotz M, Pape HC, Gruner A, Jochum M, Regel G. Aprotinin prevents the development of the trauma-induced Multiple Organ Failure in a chronic sheep model. Eur. J. Clin. Chem. Clin. Biochem. 1996; 34: 207-214.
10. Bader A, Knop E, Kern A, Böker K, Frühauf N, Crome O, Esselmann H, Pape HC, Kempka G, Sewing KF. 3-D Coculture of hepatic sinusoidal cells with primary hepatocytes - design of an organotypical model. Experimental Cell Research 1996 Jul 10;226(1):223-33.
20 Curriculum Vitae, HC Pape MD, FACS
11. Grotz M, Regel G, Schratt HE, Seekamp A, Pape HC, Tscherne H. Intestinale Zytokinfreisetzung nach Darmischämie in der Ratte - Untersuchungen im Ussing-Kammersystem. Zeitschrift für Gastroenterologie 1996; 34: 735-742.
12. Remmers D, Dwenger A, Grotz M, Pape HC, Gruner A, Hafemann R, Regel G. Attenuation of multiple organ dysfunction in a chronic sheep model by the 21- aminosteroid U74389 G. J Surgical Research 1996; 62: 278-283.
13. Tscherne H, Regel G, Pape HC, Pohlemann T, Krettek C. Internal fixation of multiple fractures in patients with polytrauma. Clin Orthop Relat Res. 1998 Feb;(347):62-78.
14. Remmers D, Neumann C, Pape HC, Post-Stanke A, Regel G, Tscherne H. Das polytraumatisierte Kind: Ein retrospektiver Vergleich zwischen polytrau- matisierten Kindern, Jugendlichen und Erwachsenen. Unfallchirurg 1998; 101: 388- 394.
15. Lehmann C, Tschernig T, Remmers D, Pape HC, Gruner A, Krug N, Pabst R. Induction of ARDS-like acute lung injury in the experimentally induced MOF of sheep results in decreased numbers of T-Lymphocytes in BAL. J Experimental Animal Science 1998; 39: 167-176.
16. Beutler S, Regel G, Pape HC, Machtens S, Weinberg A, Jonas U, Tscherne H. Die extrakorporale Stoßwellentherapie (ESWT) in der Behandlung von Pseudarthrosen des Röhrenknochens. Unfallchirurg 1999; 102-11: 839-847.
17. Lehmann U, Pape HC, Seekamp A, Gobiet W, Zech S, Winny M, Molitoris U, Regel G. Long term results after multiple injuries including severe head injury. Eur J Surg. 1999 Dec;165(12):1116-20.
18. Krettek C, Stephan C, Schandelmaier P, Richter M, Pape HC, Miclau T. The use of poller screws as blocking screws in stabilising tibial fractures with small diameter intramedullary nails. J Bone Joint Surgery 1999; 81-B: 963-968.
19. Tscherne H, Pohlemann T, Gänsslen A, Hüfner T, Pape HC. Crush injuries of the pelvis. Eur J Surg. 2000 Apr;166(4):276-82.
20. Zdichavsky M, Hüfner T, Pape HC, Rosenthal H, Tscherne H. Posttraumatrische Osteolyse des distalen Klavikulaendes. Unfallchirurg 2000; 103: 1121-1123.
21. Marzi I, Lehnert M, Georg T, Grotz M, Pape HC, Cortbus F. Multiorganversagen auf operativen und nicht-operativen Intensivstationen im Vergleich. Intensivmedizin und Notfallmedizin 2000; 37: 688-700.
22. Böttcher F, Breddin M, van Griensven M, Schneider D, Langer W, Pape HC. Quality management in experimental research: A new software to coordinate the timing, the completeness and the plausibility of data collection. European J Trauma 2000; 4: 191-192.
21 Curriculum Vitae, HC Pape MD, FACS
23. Grotz M, Pape HC, Stalp M, van Griensven M, Schreiber T, Krettek C. Langzeitverlauf nach Multiorganversagen bei Polytrauma. Der Anästhesist 2001; 50: 262-270.
24. Hüfner T, Thermann H, Geerling J, Pape HC, Pohlemann T Primary subtalar arthrodesis of calcaneal fractures. Foot & Ankle International 2001; 22(1).
25. Stalp M, Regel G, Krettek C, Pape HC. AG Polytrauma der DGU Entwicklung eines standardisierten Instruments zur quantitativen und reproduzierbaren Rehabilitationserfassung nach Polytrauma (HASPOC). Der Chirurg 2001; 72: 312-318.
26. Grotz M, van Griensven M, Stalp M, Rohde F, Hildebrand F, Krettek C, Pape HC. Organ-specific cytokine gene expression in sepsis – a study in a two-hit septic model. European J Trauma 2001; 27(4): 191-198.
27. Grotz M, van Griensven M, Stalp M, Kaufmann U, Hildebrand F, Pape HC. Scoring des Multiorganversagens nach schwerem Trauma – Vergleich des Goris-, Marshall- und Moore-Scores. Der Chirurg 2001; 72(6): 723-730.
28. Weinberg A, Pietsch I, Krefft M, Pape HC, van Griensven M, Helm M, Reilmann H, Tscherne H. Die Pro- und Supination des Unterarms - Unter besonderer Berücksichtigung der Articulatio humeroulnaris. Unfallchirurg 2001; 104(5): 404-409.
29. Oberbeck R, Dahlweid M, Koch R, van Griensven M, Emmendörfer A, Tscherne H, Pape HC. Dehydroepiandrosterone decreases mortality rate and improves cellular immune function during polymicrobial sepsis. Critical Care Medicine 2001; 29(2): 380-384.
30. Richter M, Otte D, Pape HC, Gluer S, Könemann B, Tscherne H. Problematik der Verletzungen von Kindern und Jugendlichen im Straßenverkehr. Unfallchirurg 2001;104(8): 733-741.
31. Adams HA, Baumann G, Gänsslen A, Janssens U, Knoefel W, Koch T, Marx G, Pape HC, Prange W, Standl T, Teske W, Werner G, Zander R, IAG Schock. Definition der Schockformen. Anesthesiol Intensivmed Notfallmed Schmerzther 2001; 36(l2): 140-143.
32. Grotz M, Pape HC, van Griensven M, Stalp M, Rohde F, Bock D, Krettek C. Glycine reduces the inflammatory response and organ damage in a two-hit sepsis model in rats. Shock 2001; 16(2): 116-121.
33. Richter M, Krettek C, Otte D, Wiese B, Stalp M, Ernst S, Pape HC. Correlation between crash severity, injury severity and clinical course in car occupants with thoracic trauma: a technical and medical study. J Trauma 2001; 51(1): 10-16.
22 Curriculum Vitae, HC Pape MD, FACS
34. Giannoudis P, Veysi V, Pape HC, Krettek C, Smith R. When should we operate on major fractures in patients with severe head injuries? Amer J Surgery 2002; 183: 261-267.
35. Stalp M, Koch C, Ruchholtz S, Panzica M, Krettek C, Pape HC. Standardized outcome evaluation after blunt multiple injuries by scoring systems: A clinical follow-up investigation 2 years after injury. J Trauma 2002; 52(6): 1160-1168.
36. Hildebrand F, van Griensven M, Garapati R, Krettek C, Pape HC. Diagnostics and scoring in blunt chest trauma. European J Trauma 2002; 28(2): 157-167.
37. Oberbeck R, van Griensven M, Nickel E, Tschernig T, Wittwer T, Pape HC. Influence of beta-adrenoceptor antagonists on hemorrhage-induced cellular immune suppression. Shock 2002;18(4): 331-335.
38. Van Griensven M, Zeichen J, Tschernig T, Seekamp A, Pape HC. A modified method to culture human osteoblasts from bone tissue specimens using fibrin glue. Experimental Toxicology Pathology 2002; 54: 25-29.
39. Van Griensven M, Kuzu M, Breddin M, Krettek C, Pape HC, Tschernig T. Polymicrobial sepsis induces organ changes due to granulocyte adhesion in a murine two hit model of trauma. Experimental Toxicology Pathology 2002; 54: 203-209.
40. Oberbeck R, Nickel E, van Griensven M, Tschernig T, Wittwer T, Pape HC. The effect of DHEA on hemorrhage-induced suppression of cellular immune function. Intensive Care Medicine 2002; 28: 963-968.
41. Przkora R, Bosch U, Zelle B, Panzica M, Garapati R, Krettek C, Pape HC. Damage control orthopedics: A case report. J Trauma 2002; 53(4): 765-769.
42. Zelle B, Zeichen J, Pape HC, Weissenborn K, Krettek C. Upper sympathetic trunk lesion after video-assisted fracture stabilization of the thoracic spine: a case report. J Spinal Disord Tech. 2002; 15(6): 502-6.
43. Van Griensven M, Dahlweid FM, Giannoudis PV, Wittwer T, Böttcher F, Breddin M, Pape HC. Dehydroepiandrosterone (DHEA) modulates the activity and the expression of lymphocyte subpopulations induced by cegal ligation and puncture. Shock 2002; 18(59): 445-449.
44. Gänsslen A, Pape HC, Lehmann U, Lange U, Krettek C, Pohlemann T. Open reduction and internal fixation of unstable sacral fractures. Zentralblatt Chirurgie 2003; 128(1): 40-45.
45. Zelle B, Stalp M, Weihs Ch, Müller F, Reiter FO, Krettek C, Pape HC. Arbeitsgemeinschaft Polytrauma der DGU Hannover Score für Polytrauma Outcome (HASPOC). Chirurg 2003; 74:361-369.
23 Curriculum Vitae, HC Pape MD, FACS
46. Meier R, van Griensven M, Pape HC, Krettek C, Chawda M, Seekamp A. Effects of cardiac contusion in isolated perfused rat hearts. Shock 2003; 19: 123-126.
47. Hildebrand F, Pape HC, Hoevel P, Krettek C, van Griensven M. The importance of systemic cytokines in the pathogenesis of polymicrobial sepsis and dehydroepiandrosterone treatment in a rodent model. Shock 2003; 20(4): 338-346.
48. Schwermann T, Pape HC, Grotz M, Blanke M, Greiner W, Tröger M, Stalp M, AG Polytrauma der DGU, Graf von der Schulenburg JM, Krettek C. Einflussfaktoren auf die Überlebenswahrscheinlichkeit beim Polytrauma. Gesundheitsökonomie und Qualitätsmanagement 2003; 8:285-289.
49. Ruchholtz S, Schwermann T, Lefering R, Grotz M, Pape HC, AG Polytrauma der Deutschen Gesellschaft für Unfallchirurgie. Was kostet ein Schwerverletzter im Schockraum? Journal für Anästhesie u. Intensivmedizin 2003; 1: 25-28.
50. Van Griensven M, Krettek C, Pape HC. Immune reactions after trauma. European J Trauma 2003; 29(4): 181-192.
51. Grotz M, Schwermann T, Mahlke L, Ruchholtz S, Lefering R, Graf v.d. Schulenburg JM, Krettek C, Pape HC, AG Polytrauma der DGU. DRG-Entlohnung beim Polytrauma – ein Vergleich mit den tatsächlichen Kranken- hauskosten anhand des DGU-Traumaregisters. Unfallchirurg 2003; 107(4): 348-57.
52. Gänsslen A, Giannoudis P, Pape HC. Hemorrhage in pelvic fracture: who needs angiography? Current Opinion in Critical Care 2003; 9 (6): 515-23.
53. Zelle BA, Pape HC, Gerich TG, Garapati R, Ceylan B, Krettek C. Functional outcome following scapulothoracic dissociation. J Bone Joint Surg Am. 2004; 86- A(1):2-8.
54. Hankemeier S, Paley D, Pape HC, Zeichen J, Gosling T, Krettek C. Die kniegelenknahe Focal-dome-Osteotomie. Orthopäde 2004; 33(2): 170-7.
55. Bading S, Pape HC, Lange U, Bastian L, Krettek C. Zur Problematik der Reosteosynthese bei Denspseudarthrose. Unfallchirurg 2004; 107(2): 149-53.
56. Hildebrand F, Giannoudis PV, van Griensven M, Chawda M. Pape HC. Pathophysiologic changes and effects of hypothermia on outcome in elective surgery and trauma patients. American J Surgery 2004; 187(3): 363-71.
57. Hankemeier S, Pape HC, Gosling T, Hufner T, Richter M, Krettek C. Improved comfort in lower limb lengthening with the intramedullary skeletal kinetic distractor - principles and preliminary clinical experiences. Arch Orthop Trauma Surgery 2004;124(2): 129-33. Epub 2004 Jan 27.
24 Curriculum Vitae, HC Pape MD, FACS
58. Panzica M, Garapati R, Zelle B, Krettek C, Tscherne H, Pape HC. Combination of femoral fracture treatment and corrective osteotomy in a child with osteogenesis imperfecta. Arch Orthop Trauma Surgery 2004 Jun;124(5):341-5. Epub 2004 Mar 18
59. Zelle BA, Gerich TG, Bastian L, Shuler FD, Pape HC, Krettek C. Total hip arthroplasty in young patients using the thrust plate prosthesis: clinical and radiological results. Arch Orthop Trauma Surg. 2004 Jun; 124(5):310-6. Epub 2004 April 14.
60. Chawda MN, Hildebrand F, Pape HC, Giannoudis PV. Predicting outcome after multiple trauma: which scoring system? Injury 2004; 35(4):347-58.
61. Grimme K, Gosling T, Pape HC, Schandelmaier P, Krettek C. Fracture of the medial femoral condyle as a complication of retrograde femoral nail removal. Unfallchirurg 2004 Jun;107(6):532-6. Epub 2004 Apr 2.
62. Hildebrand F, Pape HC, Harwood P, Wittwer T, Krettek C, van Griensven M. Are alterations of lymphocyte subpopulations in polymicrobial sepsis and DHEA treatment mediated by the tumour necrosis factor (TNF)-alpha receptor (TNF-RI)? A study in TNF-RI (TNF-RI(-/-)) knock-out rodents. Clin-Exp-Immunol. 2004;138(2): 221-9.
63. Giannoudis PV, Pape HC. Damage control orthopaedics in unstable pelvic ring injuries. Injury 2004; 35(7): 671-7.
64. Hildebrand F, Giannoudis P, Kretteck C, Pape HC. Damage control: extremities. Injury 2004; 35(7): 678-89.
65. Bading S, Pape HC, Lange U, Bastian L, Krettek C. Zur Problematik der Reosteosynthese bei Denspseudarthrose. Fallbericht und Literatursammlung. Unfallchirurg 2004; 107(2): 149-53.
66. van-Griensven M, Barkhausen T, Hildebrand F, Grotz M, Krettek C, Pape HC. L- selectin shows time and gender dependency in association with MODS. Injury 2004 Nov; 35(11): 1087-95.
67. Schwermann T, Grotz M, Blanke M, Ruchholtz S, Lefering R, v.d. Schulenburg JM, Krettek C, Pape HC. Evaluation of costs incurred for patients with multiple trauma particularly from the perspective of the hospital. Unfallchirurg 2004; 107(7): 563- 74.
68. Raman R, Sidhom S, Pape HC, Giannoudis PV. Systemic effects of bilateral tibial versus bilateral femoral shaft fractures. Is there a difference? Acta Orthop Belg. 2004;70(2)134-41.
69. Lange U, Pape HC, Bastian L, Krettek L. [Operative management of cervical spine injuries in patients with Bekhterev’s disease.] Unfallchirurg 2005 Jan; 108(1):63-8.
25 Curriculum Vitae, HC Pape MD, FACS
70. Zelle BA, Brown SR, Panzica M, Lohse R, Sittaro NA, Krettek C, Pape HC. The impact of injuries below the knee joint on the long term functional outcome following polytrauma. Injury 2005 Jan; 36(1): 169-77.
71. Hankemeier S, Gosling T, Pape HC, Weibking U, Krettek C. Limb lengthening with the Intramedullary Skeletal Kinetic Distractor (ISKD). Oper Orthop Traumatol. 2005 Feb; 17(1): 79-101.
72. Hildebrand F, Giannoudis PV, Griensven M, Zelle B, Ulmer B, Krettek C, Bellamy MC, Pape HC. Management of polytraumatized patients with associated blunt chest trauma: a comparison of two European countries. Injury 2005 Feb; 36(2):293-302.
73. Harwood PJ, Giannoudis PV, van Griensven M, Krettek C, Pape HC. Alterations in the systemic inflammatory response after early total care and damage control procedures for femoral shaft fracture in severely injured patients. J Trauma 2005 Mar; 58(3):446-52.
74. Richter M, Pape HC, Otte D, Krettek C. The current status of road user injuries among the elderly in Germany: a medical and technical accident analysis. J Trauma 2005 Mar;58(3)591-5.
75. Hildebrand F, Pape HC, Harwood P, Muller K, Hoevel P, Putz C, Siemann A, Krettek C, van Griensven M. Role of adhesion molecule ICAm in the pathogenesis of polymicrobial sepsis. Exp Toxicol Pathol 2005 Mar; 56(4-5):281-90.
76. Meier R, Krettek C, Grimme K, Regel G, Remmers D, Harwood P, Pape HC. The multiply injured child. Clin Orthop Relat Res. 2005 Mar; (432):127-31.
77. Richter M, Pape HC, Otte D, Krettek C. Improvements in passive car safety led to decreased injury severity – a comparison between the 1970’s and 1990’s. Injury 2005 Apr; 36(4):484-8.
78. Hildebrand F, Giannoudis P, van Griensven M, Chawda M, Probst C, Harms O, Harwood P, Otto K, Fehr M, Krettek C, Pape HC. Secondary effects of femoral instrumentation on pulmonary physiology in a standardised sheep model: what is the effect of lung contusion and reaming? Injury 2005 Apr; 36(4): 544-55.
79. Deepak VS, Giannoudis PV, Zelle BA, Waseem M, Pape HC. Radial artery tear complicating a distal radius fracture. Am J Orthop. 2005 Jun; 34(6):299-300.
80. Raman R, Roberts CS, Pape HC, Giannoudis PV. Implant retention and removal after internal fixation of the symphysis pubis. Injury 2005 Jul; 36(7):827-31.
81. Zelle BA, Panzica M, Vogt MT, Sitarro NA, Krettek C, Pape HC. Influence of workers’ compensation eligibility upon functional recovery 10 to 28 years after polytrauma. Am J Surg. 2005 Jul; 190(1):30-6.
26 Curriculum Vitae, HC Pape MD, FACS
82. Hildebrand F, van Griensven M, Giannoudis P, Luerig A, Harwood P, Harms O, Fehr M, Krettek C, Pape HC. Effects of hypothermia and re-warming on the inflammatory response in a murine multiple hit model of trauma. Cytokine 2005 Sep; 31(5): 382-93.
83. Hildebrand F, Pape HC, Krettek C. The importance of cytokines in the posttraumatic inflammatory reaction. Unfallchirurg 2005 Oct; 108(10):793-803.
84. Hildebrand F, Pape HC, Griensven M, Meier S, Hasenkamp S, Krettek C, Stuhrmann M. Genetic predisposition for a compromised immune system after multiple trauma. Shock 2005 Dec;24(6):518-22.
85. Grotz MR, Gummerson NW, Gansslen A, Petrowsky H, Keel M, Allami MK, Tzioupis C, Trentz O, Krettek C, Pape HC, Giannoudis PV. Staged management and outcome of combined pelvic and liver trauma An international experience of the deadly duo. Injury 2006 Jan 19; [Epub ahead of print]
86. Harwood PJ, Giannoudis PV, Probst C, Van Griensven M, Krettek C, Pape HC, The Polytrauma Study Group of the German Trauma Society. Which AIS based scoring system is the best predictor of outcome in orthopaedic blunt trauma patients? J Trauma 2006 Feb;60(2):334-40.
87. van Griensven M, Probst C, Muller K, Hoevel P, Pape HC. Leukocyte-endothelial interactions via ICAM-1 are detrimental in polymicrobial sepsis. Shock 2006 Mar;25(3):254-9.
88. Harwood PJ, Giannoudis PV, Probst C, Krettek C, Pape HC. The risk of local infective complications after damage control procedures for femoral shaft fracture. J Orthop Trauma 2006 Mar;20(3):181-9.
89. Bhandari M, Pape HC, Giannoudis PV. Issues in the planning and conduct of randomised trials. Injury 2006 Apr;34(4):349-54.
90. Hildebrand F, Hubbard WJ, Choudhry MA, Thobe BM, Pape HC, Chaudry IH. Are the protective effects of 17 {beta}-estradiol on splenic macrophages and splenocytes after trauma-hemorrhage mediated via estrogen-receptor (ER)-{alpha} or ER-{beta}? J Leukoc Biol. 2006 Jun;79(6):1173-80.
91. Zelle BA, Gruen GS, Espiritu M, Pape HC. Posterior Blade Fusion: A Salvage Procedure in Severe Posttraumatic Osteoarthritis of the Tibiotalar Joint. Op Tech Ortho. 2006 (16): 68-75.
92. Hildebrand F, Hubbard WJ, Choudhry MA, Frink M, Pape HC, Kunkel SL, Chaudry IH. Kupffer cells and their mediators: the culprits in producing distant organ damage after trauma-hemorrhage. Am J Pathol. 2006 Sep;169(3):784-94.
27 Curriculum Vitae, HC Pape MD, FACS
93. Hildebrand F, Winkler M, van Griensven M, Probst C, Musahl V, Krettek C, Pape HC. Blunt Abdominal Trauma Requiring Laparotomy: an Analysis of 342 Polytraumatized Patients. Europ J Trauma 2006 (32): 430-8.
94. Giannoudis PV, Mushtaq S, Harwood P, Kambhampati S, Dimoutsos M, Stavrou Z, Pape HC. Accelerated bone healing and excessive callus formation in patients with femoral fracture and head injury. Injury 2006 Sep;37 Suppl 3:S18-24.
95. Hildebrand F, Hubbard WJ, Choudhry MA, Thobe BM, Pape HC, Chaudry IH. Effects of 17beta-estradiol and flutamide on inflammatory response and distant organ damage following trauma-hemorrhage in metestrus females. J Leukoc Biol. 2006 Oct;80(4):759-65.
96. Kontakis GM, Tossounidis T, Weiss K, Pape HC, Giannoudis PV. Fat embolism: special situations bilateral femoral fractures and pathologic femoral fractures. Injury 2006 Oct;37 Suppl 4:S19-24.
97. Giannoudis PV, Tzioupis C, Pape HC. Fat embolism: the reaming controversy. Injury 2006 Oct;37 Suppl 4:S50-8.
98. Allami MK, Partenheimer A, Sommer K, Jamil W, Gerich T, Krettek C, Pape HC. Complete Aortic Rupture in a Polytrauma Patient: Damage Control Orthopaedics. J Trauma 2006 Nov 13; [Epub ahead of print]
99. Hildebrand F, Thobe BM, Hubbard WJ, Choudhry MA, Pape HC, Chaudry IH. Effects of 17beta-estradiol and flutamide on splenic macrophages and splenocytes after trauma-hemorrhage. Cytokine 2006 Nov;36(3-4):107-14.
100. Giannoudis PV, Pountos I, Pape HC, Patel JV. Safety and efficacy of vena cava filters in trauma patients. Injury 2007 Jan;38(1):7-18.
101. Frink M, Probst Ch, Krettek Ch, Pape HC. [Clinical management of polytraumatized patients in the emegergency room--duty and assignment of the trauma surgeon]. Zentralbl Chir. 2007 Feb;132(1):49-53.
102. Frink M, Pape HC, van Griensven M, Krettek C, Chaudry IH, Hildebrand F. Influence of sex and age on mods and cytokines after multiple injuries. Shock 2007 Feb;27(2):151-6.
103. Probst C, Probst T, Gaensslen A, Krettek C, Pape HC; the Polytrauma Study Group of the German Trauma Society. Timing and duration of the initial pelvic stabilization after multiple trauma in patients from the German trauma registry: is there an influence on outcome? J Trauma 2007 Feb;62(2):370-7.
104. Kobbe P, Frink M, Zelle BA, Pape HC. [Complex knee injury in polytraumatized patients.] Unfallchirurg 2007 Mar;110(3):235-44.
28 Curriculum Vitae, HC Pape MD, FACS
105. Sittaro NA, Lohse R, Panzica M, Probst C, Pape HC, Krettek C. [Hannover- Polytrauma-Longterm-Study HPLS] Versicherungsmedizin 2007 Mar 1;59(1):20-5.
106. Alpantaki K, Tsiridis E, Pape HC, Giannoudis PV. Application of clinical proteomics in diagnosis and management of trauma patients. Injury 2007 Mar;38(3):263-71.
107. Frink M, Probst C, Hildebrand F, Richter M, Hausmanninger C, Wiese B, Krettek C, Pape HC; AG Polytrauma der DGU. [The influence of transportation mode on mortality in polytraumatized patients: An analysis based on the German Trauma Registry.] Unfallchirurg 2007 Apr;110(4):334-340.
108. Wrann CD, Tabriz NA, Barkhausen T, Klos A, van Griensven M, Pape HC, Kendoff DO, Guo R, Ward PA, Krettek C, Riedemann NC. The phosphatidylinositol 3-kinase signaling pathway exerts protective effects during sepsis by controlling C5a-mediated activation of innate immune functions. J Immunol. 2007 May 1;178(9):5940-8.
109. Frink M, Klaus AK, Kuther G, Probst C, Gosling T, Kobbe P, Hildebrand F, Richter M, Giannoudis PV, Krettek C, Pape HC. Long term results of compartment syndrome of the lower limb in polytraumatised patients. Injury 2007 May;38(5):607-13.
110. Hildebrand F, Stuhrmann M, van Griensven M, Meier S, Hasenkamp S, Krettek C, Pape HC. Association of IL-8-251A/T polymorphism with incidence of Acute Respiratory Distress Syndrome (ARDS) and IL-8 synthesis after multiple trauma. Cytokine. 2007 May 9; [Epub ahead of print]
111. Tzioupis CC, Kobbe P, Tarkin IS, Pape HC. Pelvic stabilization. Prehospital management of traumatic pelvic injuries. JEMS 2007 Jul;32(7):64-6, 68, 70-5.
112. Frink M, Kaudel CP, Hildebrand F, Pape HC, Klempnauer J, Winkler M, Krettek C, van Griensven M. FTY720 improves survival after transient ischemia and reperfusion of the hind limbs. J Trauma 2007 Aug; 63(2):263-7.
113. Giannoudis PV, Psarakis S, Kanakaris NK, Pape HC. Biological enhancement of bone healing with Bone Morphogenetic Protein-7 at the clinical setting of pelvic girdle non-unions. Injury 2007 Sep;38 Suppl 4:S43-8.
114. Giannoudis PV, van Griensven M, Tsiridis E, Pape HC. The genetic predisposition to adverse outcome after trauma. J Bone Joint Surg Br. 2007 Oct;89(10):1273-9.
115. Kobbe P, Vodovotz Y, Kaczorowski D, Mollen KP, Billiar TR, Pape HC. Patterns of cytokine release and evolution of remote organ dysfunction after bilateral femur fracture. Shock 2007 Nov 8 [Epub ahead of print]
116. Frink M, Hsieh YC, Hu S, Hsieh CH, Pape HC, Choudhry MA, Schwacha MG, Bland KI, Chaudry IH. Mechanism of salutary effects of finasteride on post-
29 Curriculum Vitae, HC Pape MD, FACS
traumatic immune/inflammatory response: upregulation of estradiol synthesis. Ann Surg. 2007 Nov; 246(5):836-43.
117. Frink M, Hsieh YC, Hsieh CH, Pape HC, Choudhry MA, Schwacha MG, Chaudry IH. Keratinocyte-derived chemokine plays a critical role in the induction of systemic inflammation and tissue damage after trauma-hemorrhage. Shock 2007 Nov;28(5):576-81.
118. Giannoudis PV, Pape HC. Trauma and immune reactivity: Too much, or too little immune response? Injury 2007 Dec;38(12):1333-5.
119. Giannoudis PV, Pountos I, Morley J, Perry S, Tarkin HI, Pape HC. Growth factor release following femoral nailing. Bone 2008 Jan 10 [Epub ahead of print]
120. Giannoudis PV, van Griensven M, Hildebrand F, Krettek C, Pape HC. Femoral Nailing-related Coagulopathy Determined by First-hit Magnitude: An Animal Study. Orthop Relat Res. 2008 Feb;466(2):473-80.
121. Tarkin IS, Clare MP, Marcantonio A, Pape HC. An update on the management of high-energy pilon fractures. Injury 2008 Feb;39(2):142-54.
122. Kobbe P, Tarkin IS, Frink M, Pape HC. [Voluminous bone graft harvesting of the femoral marrow cavity for autologous transplantation: An indication for the"Reamer-Irrigator-Aspirator-" (RIA-) technique.] Unfallchirurg 2008 Feb 15 [Epub ahead of print]
123. Kobbe P, Frink M, Oberbeck R, Tarkin IS, Tzioupis C, Nast-Kolb D, Pape HC, Reilmann H. [Treatment strategies for gunshot wounds of the extremities] Unfallchirurg 2008 Apr;111(4):247-54
124. Kobbe P, Frink M, Oberbeck R, Tarkin IS, Tzioupis C, Nast-Kolb D, Pape HC, Reilmann H. [Treatment of a shotgun fracture of the humerus] Unfallchirurg 2008 Apr;111(4):256-9
125. Pountos I, Georgouli T, Blokhuis TJ, Pape HC, Giannoudis PV. Pharmacological agents and impairment of fracture healing: what is the evidence? Injury 2008 Apr;39(4):384-94. Epub 2008 Mar 7.
126. Giannoudis PV, Pountos I, Morley J, Perry S, Tarkin HI, Pape HC. Growth factor release following femoral nailing. Bone 2008 Apr;42(4):751-7. Epub 2008 Jan 10.
127. Barkhausen T, Frerker C, Pütz C, Pape HC, Krettek C, van Griensven M. Depletion of NK cells in a murine polytrauma model is associated with improved outcome and a modulation of the inflammatory response. Shock 2008 Apr 3. [Epub ahead of print]
128. Siska PA, Gruen GS, Pape HC. External adjuncts to enhance fracture healing: What is the role of ultrasound? Injury 2008 Apr 14. [Epub ahead of print]
30 Curriculum Vitae, HC Pape MD, FACS
129. Tomycz ND, Chew BG, Chang YF, Darby JM, Gunn SR, Nicholas DH, Ochoa JB, Peitzman AB, Schwartz E, Pape HC, Spiro RM, Okonkwo DO. MRI is unnecessary to clear the cervical spine in obtunded/comatose trauma patients: the four-year experience of a level I trauma center. J Trauma 2008 May;64(5):1258-63.
130. Kobbe P, Kaczorowski DJ, Vodovotz Y, Tzioupis CH, Mollen KP, Billiar TR, Pape HC. Local exposure of bone components to injured soft tissue induces toll-like- receptor-4 dependent systemic inflammation with acute lung injury. Shock 2008 May 2. [Epub ahead of print]
131. Kobbe P, Tarkin IS, Frink M, Pape HC. Voluminous bone graft harvesting of the femoral marrow cavity for autologous transplantation: An indication for the"Reamer-Irrigator-Aspirator-" (RIA-) technique.] Unfallchirurg. 2008 Jun;111(6):469-72.
132. Mirzayan MJ, Probst C, Krettek C, Samii M, Pape HC, van Griensven M, Samii A. Systemic effects of isolated brain injury: an experimental animal study. Neurol Res. 2008 June;30(5):457-60.
133. Kobbe P, Tarkin IS, Pape HC. Use of the 'reamer irrigator aspirator' system for non- infected tibial non-union after failed iliac crest grafting. Injury 2008 Jul;39(7):796- 800. Epub 2008 Jun 9.
134. Kobbe P, Vodovotz Y, Kaczorowski DJ, Mollen KP, Billiar TR, Pape HC. Patterns of cytokine release and evolution of remote organ dysfunction after bilateral femur fracture. Shock 2008 Jul;30(1):43-47.
135. Kobbe P, Vodovotz Y, Kaczorowski DJ, Billiar TR, Pape HC. The role of fracture- associated soft tissue injury in the induction of systemic inflammation and remote organ dysfunction after bilateral femur fracture. Journal of Orthop Trauma 2008 Jul;22(6):385-90.
136. Pfeifer R, Pape HC. Missed injuries in trauma patients: A literature review. Patient Safety in Surgery 2008 Aug. 23;2:20.
137. Quintero AJ, Tarkin IS, Pape HC. Case Report: The Prone Reduction of a Sacroiliac Disruption with a Pelvic C-clamp. Clinical Orthopaedics Related Research 2008 Sept. 23. [Epub ahead of print]
138. Giannoudis PV, Harwood PJ, Loughenbury P, van Griensven M, Krettek C, Pape HC. Correlation between IL-6 levels and the systemic inflammatory response score: can an IL-6 cutoff predict a SIRS state? Journal of Trauma 2008 Sept.; 65(3)646-52.
139. Kobbe P, Tarkin IS Oberbeck R, Pape HC. Damage control orthopaedics in polytraumatised patients with lower leg injuries. Z Orthop Unfall. 2008 Sept- Oct;146(5):580-5. German [Epub 2008 Oct 9.Review]
31 Curriculum Vitae, HC Pape MD, FACS
140. Tarkin IS, Perricelli BC, Pape HC. Exercise induced compartment syndrome of the pectoralis major/deltoid in a professional tree climber. Journal of Shoulder Elbow Surgery 2008 Nov. 24. [Epub ahead of print]
141. Webb LX, Pape HC. Current thought regarding the mechanism of action of negative pressure wound therapy with reticulated open cell foam. Journal of Orthopaedic Trauma 2008 Nov-Dec;22(10 Suppl):S135-7.
142. Mommsen P, Frink M, Pape HC, van Griensven M, Probst C, Gaulke R, Krettek C, Hildebrand F. Elevated systemic IL-18 and neopterin levels are associated with posttraumatic complications among patients with multiple injuries: A prospective cohort study. Injury 2008 Dec. 1. [Epub ahead of print]
143. Tarkin IS, Sop A, Pape HC. High-energy foot and ankle trauma: principles for formulating an individualized care plan. Foot Ankle Clin. 2008 Dec.; 13(4):705-23.
144. Siska P, Gruen GS, Menzel C, Pape HC. External adjuncts to enhance fracture healing: What is the role of ultrasound? Unfallchirurg 2008 Dec. 20. [Epub ahead of print]
145. Probst C, Pape HC, Hildebrand F, Regel G, Mahlke L, Giannoudis p, Krettek C, Grotz MR. 30 years of polytrauma care: An analysis of the change in strategies and results of 4849 cases treated at a single institution. Injury 2008 Dec. 29. [Epub ahead of print]
146. Kobbe P, Stoffels B, Schmidt J, Tsukamoto T, Gutkin DW, Bauer AJ, Pape HC. IL- 10 deficiency augments acute lung but not liver injury in hemorrhagic shock. Cytokine 2009 Jan;45(1):26-31. Epub 2008 Nov. 17.
147. Tsukamoto T, Pape HC. Animal models for trauma research: what are the options? Shock 2009 Jan;31(1):3-10.
148. Kobbe P, Schmidt J, Stoffels B, Chanthaphavong RS, Bauer AJ, Pape HC. IL-10 administration attenuates pulmonary neutrophil infiltration and alters pulmonary iNOS activation following hemorrhagic shock. Inflamm Res. 2009 Mar;58(3):170-4
149. Barkhausen T, Probst C, Hildebrand F, Pape HC, Krettek C, van Griensven M. Insulin therapy induces changes in the inflammatory response in a murine 2-hit model. Injury 2009 Jan 22.
150. Giannoudis PV, Harwood PJ, Court-Brown C, Pape HC. Severe and multiple trauma in older patients; incidence and mortality. Injury 2009 Apr;40(4):362-7
151. Musahl V, Tarkin I, Kobbe P, Tzioupis C, Siska PA, Pape HC. New trends and techniques in open reduction and internal fixation of fractures of the tibial plateau. J Bone Joint Surg Br. 2009 Apr;91(4):426-33
32 Curriculum Vitae, HC Pape MD, FACS
152. Pfeifer R, Pape HC. Late death after multiple severe trauma: when does it occur and what are the causes? J Trauma 2009 Apr;66(4):1212-7
153. Tsukamoto T, Savanh Chanthaphavong R, Pape HC. Current theories on the pathophysiology of multiple organ failure after trauma. Injury 2009 Sep 1.
154. Probst C, Hildebrand F, van Griensven M, Baur H, Mahlke L, Krettek C, Pape HC, Grotz MR. Is dopexamine superior to dopamine in the treatment of multiple trauma patients-A prospective, double-blind, randomised study. Injury 2009 Jul 10
155. Pfeifer R, Tarkin IS, Rocos B, Pape HC. Patterns of mortality and causes of death in polytrauma patients--has anything changed? Injury 2009 Sep;40(9):907-11.
156. Schmidt-Rohlfing B, Tzioupis C, Menzel CL, Pape HC. Tissue engineering of bone tissue. Principles and clinical applications. Unfallchirurg 2009 Sep;112(9):785-94
157. Wiese A, Pape HC. Bone defects caused by high-energy injuries, bone loss, infected nonunions, and nonunions. Orthop Clin North Am. 2010 Jan;41(1):1-4.
158. Kline AJ, Gruen GS, Pape HC, Tarkin IS, Irrgang JJ, Wukich DK. Early complications following the operative treatment of pilon fractures with and without diabetes. Foot Ankle Int. 2009 Nov;30(11):1042-7.
159. Kobbe P, Lichte P, Pape HC. Complex extremity fractures following high energy injuries: the limited value of existing classifications and a proposal for a treatment- guide. Injury 2009 Nov;40 Suppl 4:S69-74.
160. Zeckey C, Hildebrand F, Mommsen P, Schumann J, Frink M, Pape HC, Krettek C, Probst C. Risk of symptomatic heterotopic ossification following plate osteosynthesis in multiple trauma patients: an analysis in a level-1 trauma center. Scand J Trauma Resusc Emerg Med. 2009 Oct 13;17(1):55.
161. Giannoudis PV, Suk M, Pape HC. RIA: The journey just started but what the future holds? Injury 2010;41 Suppl 2: S1-3; Impact(2010)=2.269
162. Giannoudis PV, Mallina R, Harwood P, Perry S, Sante ED, Pape HC. Pattern of release and relationship between HMGB-1 and IL-6 following blunt trauma. Injury 2010;41(12): 1323-1327; Impact(2010)=2.269
163. Gosemann JH, van Griensven M, Barkhausen T, Kobbe P, Thobe BRM, Haasper C, Pape HC, Krettek C, Hildebrand F, Frink M. TLR4 influences the humoral and cellular immune response during polymicrobial sepsis. Injury 2010;41(10): 1060- 1067; Impact(2010)=2.269
164. Pfeifer R, Sellei R, Pape HC. The biology of intramedullary reaming. Injury 2010;41 Suppl 2: S4-8; Impact(2010)=2.269
33 Curriculum Vitae, HC Pape MD, FACS
165. Probst C, Hildebrand F, van Griensven M, Baur H, Mahlke L, Krettek C, Pape HC, Grotz MR. Is dopexamine superior to dopamine in the treatment of multiple trauma patients—a prospective, double-blind, randomised study. Injury 2010;41(5): 499- 505 ; Impact(2010)=2.269
166. Tsukamoto T, Chanthaphavong RS, Pape HC. Current theories on the pathophysiology of multiple organ failure after trauma. Injury. 2010;41(1): 21-6; Impact(2010)=2.269
167. Probst C, Zelle B, Panzica M, Lohse R, Sitarro NA, Krettek C, Pape HC. Clinical re-examination 10 or more years after polytrauma: is there a gender related difference? J Trauma 2010;68(3): 706-11 ; Impact(2010)=3.129
168. Steel J, Youssef M, Pfeifer R, Ramirez JM, Probst C, Sellei R, Zelle BA, Sittaro NA, Khalifa F, Pape HC. Health-related quality of life in patients with multiple injuries and traumatic brain injury 10+ years postinjury. J Trauma 2010;69(3): 523- 30; discussion 530-1 ; Impact(2010)=3.129
169. Knobe M, Munker R, Sellei RM, Holschen M, Mooij SC, Schmidt-Rohlfing B, Niethard FU, Pape HC. Peer teaching: a randomised controlled trial using student- teachers to teach musculoskeletal ultrasound. Med Educ. 2010;44(2): 148-155: Impact(2010)=2.639
170. Wiese A, Pape HC. Bone defects caused by high-energy injuries, bone loss, infected nonunions, and nonunions. Orthop Clin North Am. 2010;41(1): 1-4, table of contents .Impact(2010)=1.398
171. Lichte P, Oberbeck R, Binnebösel M, Wildenauer R, Pape HC, Kobbe P. A civilian perspective on ballistic trauma and gunshot injuries. Scand J Trauma Resusc Emerg Med. 2010;18:35.
172. Lichte P, Kobbe P, Lörken M, Pape HC. [Planning of corrective osteotomies of the lower limb]. Unfallchirurg 2010;113(7): 573-83, quiz 584. Impact(2010)=0.675
173. Lichte P, Kobbe P, Sellei RM, Pape HC. [Angular wedge osteotomy for correction of posttraumatic malpositions of the femur shaft]. Unfallchirurg 2010;113(7): 585- 8 : Impact(2010)=0.675
174. Schmidt-Rohlfing B, Reilmann H, Pape HC. [Fractures of the acetabulum. Diagnostic and therapeutic strategies]. Unfallchirurg 2010;113(3): 217-29. Impact(2010)=0.675
175. Sürmer KM, Raschke MJ, Burger C, Josten C, Jürgens C, Krettek C, Meffert R, Mittlmeier T, Pape HC, Marzi I. Convention of holders of university-chairs in trauma surgery: key points on terms of reference for trauma surgery in universities-- structural considerations on healthcare, research and teaching. Unfallchirurg 2010;113(11): 957-9; Impact(2010)=0.675
34 Curriculum Vitae, HC Pape MD, FACS
176. Knobe M, Sellei RM, Maus U, Mooij SC, Gradl G, Sopka S, Niethard FU, Pape HC. Undergraduate curricular training in musculoskeletal ultrasound: the impact of preexisting anatomic knowledge. Z Orthop Unfal. 2010;148(6): 685-90: Impact(2010)=0.343
177. Enninghorst N, Peralta R, Yoshino O, Pfeifer R, Pape HC, Hardy BM, Dewar DC, Balogh ZJ. Physiological assessment of the polytrauma patient: initial and secondary surgeries. Eur J Trauma Emerg Surg. 2011;37(6): 559-566: Impact(2010)=0.257
178. Lasanianos NG, Kanakaris NK, Dimitriou R, Pape HC, Giannoudis PV. Second hit phenomenon: existing evidence of clinical implications. Injury 2011;42(7): 617-29: Impact(2010)=2.269
179. Lichte P, Pape HC, Pufe T, Kobbe P, Fischer H. Scaffolds for bone healing: Concepts, materials and evidence. Injury 2011;42(6): 569-73: Impact(2010)=2.269
180. Mauffrey C, Seligson D, Lichte P, Pape HC, Al-Rayyan M. Bone graft substitutes for articular support and metaphyseal comminution: what are the options? Injury 2011;42 Suppl 2: S35-9: Impact(2010)=2.269
181. Schmidt-Rohlfing B, Pfeifer R, Kaneshige J, Hofman M, Knobe M, Sellei R, Pape HC. Scoring systems for outcome after knee injuries. Injury 2011;42(3): 271- 5: Impact(2010)=2.269
182. Schreiber VM, Tarkin IS, Hildebrand F, Darwiche S, Pfeifer R, Chelly J, Giannoudis P, Pape HC. The timing of definitive fixation for major fractures in polytrauma--a matched-pair comparison between a US and European level I centres: analysis of current fracture management practice in polytrauma. Injury 2011;42(7): 650-4: Impact(2010)=2.269
183. Steel JL, Dunlavy AC, Stillman J, Pape HC. Measuring depression and PTSD after trauma: common scales and checklists. Injury 2011;42(3): 288-300: Impact(2010)=2.269
184. Fayaz HC, Giannoudis PV, Vrahas MS, Smith RM, Moran C, Pape HC, Krettek C, Jupiter JB. The role of stem cells in fracture healing and nonunion. Int Orthop. 2011;35(11): 1587-97. Impact(2010)=1.561
185. Pfeifer R, Kobbe P, Darwiche SS, Billiar TR, Pape HC. Role of hemorrhage in the induction of systemic inflammation and remote organ damage: analysis of combined pseudo-fracture and hemorrhagic shock. J Orthop Res. 2011;29(2): 270- 4. Impact(2010)=2.976
35 Curriculum Vitae, HC Pape MD, FACS
186. Della Rocca GJ, Leung KS, Pape HC. Periprosthetic fractures: epidemiology and future projections. J Orthop Trauma 2011;25 Suppl 2: S66-70: Impact(2010)=1.792
187. Gradl G, Pape HC. Upper extremity periarticular fractures: when should they be fixed and when should they be replaced? J Orthop Trauma 2011;25 Suppl 2: S86-9: Impact(2010)=1.792
188. Sellei RM, Garrison RL, Kobbe P, Lichte P, Knobe M, Pape HC. Effects of near cortical slotted holes in locking plate constructs. J Orthop Trauma 2011;25 Suppl 1: S35-40: Impact(2010)=1.792
189. Menzel CL, Pfeifer R, Darwiche SS, Kobbe P, Gill R, Shapiro RA, Loughran P, Vodovotz Y, Scott MJ, Zenati MS, Billiar TR, Pape HC. Models of lower extremity damage in mice: time course of organ damage and immune response. J Surg Res. 2011;166(2): e149-56 : Impact(2010)=2.239
190. Köhler D, Sellei RM, Sop A, Tarkin IS, Pfeifer R, Garrison RL, Pohlemann T, Pape HC Effects of pelvic volume changes on retroperitoneal and intra-abdominal pressure in the injured pelvic ring: a cadaveric model. J Trauma 2011;71(3): 585- 90; discussion 590. Impact (2010)=3.129
191. Pfeifer R, Zelle BA, Kobbe P, Knobe M, Garrison RL, Ohm S, Sittaro NA, Probst C, Pape HC. Impact of Isolated Acetabular and Lower Extremity Fractures on Long-Term Outcome. J Trauma 2011; Impact(2010)=3.129
192. Darwiche SS, Kobbe P, Pfeifer R, Kohut L, Pape HC, Billiar T. Pseudofracture: an acute peripheral tissue trauma model. J Vis Exp. 2011;(50)
193. Menzel CL, Sun Q, Loughran PA, Pape HC, Billiar TR, Scott MJ. Caspase-1 is hepatoprotective during trauma and hemorrhagic shock by reducing liver injury and inflammation. Mol Med. 2011;17(9-10): 1031-8 : Impact(2010)=5.908
194. Tsukamoto T, Antonic V, El Hajj II, Stojadinovic A, Binion DG, Izadjoo MJ, Yokota H, Pape HC, Bauer AJ. Novel model of peripheral tissue trauma-induced inflammation and gastrointestinal dysmotility. Neurogastroenterol Motil. 2011;23(4): 379-86, e164 : Impact(2010)=3.349
195. Pfeifer R, Kobbe P, Knobe M, Pape HC. The reamer-irrigator-aspirator (RIA) System. Oper Orthop Traumatol. 2011;23(5): 446-52 (Impact(2010)=0.433
36 Curriculum Vitae, HC Pape MD, FACS
196. Fayaz HC, Jupiter JB, Pape HC, Smith RM, Giannoudis PV, Moran CG, Krettek C, Prommersberger KJ, Raschke MJ, Parvizi J. Challenges and barriers to improving care of the musculoskeletal patient of the future – a debate article and global perspective. Patient Saf Surg. 2011;5: 23
197. Pfeifer R, Lichte P, Zelle BA, Sittaro NA, Zilkens A, Kaneshige JR, Pape HC. Socio-economic outcome after blunt orthopaedic trauma: Implications on injury prevention. Patient Saf Surg. 2011;5(1): 9
198. Schmidt-Rohlfing B, Reilmann H, Pfeifer R, Kobbe P, Pape HC. Kyphoplasty and vertebroplasty. Indications, techniques, complications and results. Unfallchirurg 2011;114(5): 431-40; quiz 41-2 : Impact(2010)=0.675
199. Hofman M, Zilkens A, Pape HC. Long-term results after polytrauma. Versicherungsmedizin 2011;63(3): 137-42
200. Mooij SC, Antony P, Ruesseler M, Pfeifer R, Drescher W, Simon M, Pape HC, Knobe M. Gender-specific evaluation of student's career planning during medical study in terms of orthopaedic trauma. Z Orthop Unfall 2011;149(4): 389-94: Impact(2010)=0.343
201. Knobe M, Holschen M, Mooij SC, Sellei RM, Münker R, Antony P, Pfeifer R, Drescher W, Pape HC. Knowledge transfer of spinal manipulation skills by student-teachers: a randomised controlled trial. Eur Spine J. 2012 May;21(5):992-8.
202. Sellei RM, Kobbe P, Knobe M, Lichte P, Dienstknecht T, Lemmen SW, Pape HC. [Therapy of chronic osteomyelitis: soft tissues as "key to success"]. Orthopäde 2012 Jan;41(1):43-50.
203. Schmidt-Rohlfing B, Lemmen SW, Pfeifer R, Pape HC. [Osteomyelitis in adults. Diagnostic principles and therapeutic strategies]. Unfallchirurg 2012 Jan;115(1):55- 66.
204. Knobe M, Drescher W, Heussen N, Sellei RM, Pape HC. Is helical blade nailing superior to locked minimally invasive plating in unstable pertrochanteric fractures? Clin Orthop Relat Res. 2012 Aug;470(8):2302-12. Epub 2012 Feb 7.
205. Pfeifer R, Zelle BA, Kobbe P, Knobe M, Garrison RL, Ohm S, Sittaro NA, Probst C, Pape HC. Impact of isolated acetabular and lower extremity fractures on long- term outcome. J Trauma Acute Care Surg. 2012 Feb;72(2):467-72.
37 Curriculum Vitae, HC Pape MD, FACS
206. Pishnamaz M, Sellei R, Pfeifer R, Lichte P, Pape HC, Kobbe P. Low back pain during pregnancy caused by a sacral stress fracture: a case report. J Med Case Rep. 2012 Apr 4;6:98. doi: 10.1186/1752-1947-6-98.
207. Pfeifer R, Lichte P, Schreiber H, Sellei RM, Schmidt J, Dombroski D, Pape HC, Kobbe P. Inhalative vs. systemic IL-10 administration: differences in the systemic inflammatory response and end-organ inflammation following hemorrhagic shock. Cytokine. 2012 Oct;60(1):266-70.
208. Schmidt-Rohlfing B, Heussen N, Knobe M, Pfeifer R, Kaneshige JR, Pape HC. Re- operation rate after internal fixation of intertrochanteric femur fractures with the Percutaneous Compression Plate (PCCP): what are the risk factors? J Orthop Trauma. 2012 Sep 3. [Epub ahead of print]
209. Knobe M, Carow JB, Ruesseler M, Leu BM, Simon M, Beckers SK, Ghassemi A, Sönmez TT, Pape HC. Arthroscopy or ultrasound in undergraduate anatomy education: a randomized cross-over controlled trial. BMC Med Educ. 2012 Sep 9;12:85. doi: 10.1186/1472-6920-12-85.
210. Lichte P, Kobbe P, Dombroski D, Pape HC. Damage control orthopedics: current evidence. Curr Opin Crit Care. 2012 Oct 3. [Epub ahead of print]
211. Kobbe P, Micansky F, Lichte P, Sellei RM, Pfeifer R, Dombroski D, Lefering R, Pape HC, The TraumaRegister DGU. Increased morbidity and mortality after bilateral femoral shaft fractures: Myth or reality in the era of damage control? Injury 2012 Oct 4.
212. Darwiche SS, Pfeifer R, Menzel C, Ruan X, Hoffman M, Cai C, Chanthaphavong RS, Loughran P, Pitt BR, Hoffman R, Pape HC, Billiar TR. Inducible nitric oxide synthase contributes to immune dysfunction following trauma. Shock 2012 Nov;38(5):499-507.
213. Hildebrand F, Weuster M, Mommsen P, Mohr J, Fröhlich M, Witte I, Keibl C, Ruchholtz S, Seekamp A, Pape HC, Flohe S, Griensven VM. A Combined Trauma Model of Chest and Abdominal Trauma With Hemorrhagic Shock - Description of a new Porcine Model. Shock 2012 Oct 4. [Epub ahead of print]
214. Loosen S, Preuss S, Zelle BA, Pape HC, Tarkin IS. [Multimorbid patients with poor soft tissue conditions : Treatment of distal tibia fractures with retrograde intramedullary nailing.] Unfallchirurg 2012 Oct 3. [Epub ahead of print]
215. Pfeifer R, Pishnamaz M, Dombroski D, Heussen N, Pape HC, Schmidt-Rohlfing B. Outcome after thoracoscopic ventral stabilisation of thoracic and lumbar spine fractures. J Trauma Manag Outcomes 2012 Oct 16;6(1):10.
38 Curriculum Vitae, HC Pape MD, FACS
216. Gradl G, Knobe M, Stoffel M, Prescher A, Dirrichs T, Pape HC. Biomechanical Evaluation of Locking Plate Fixation of Proximal Humeral Fractures Augmented with Calcium Phosphate Cement. J Orthop Trauma 2012 Oct 30. [Epub ahead of print]
217. Knobe M, Gradl G, Maier KJ, Drescher W, Jansen-Troy A, Prescher A, Knechtel T, Antony P, Pape HC. Rotationally Stable Screw-Anchor versus Sliding Hip Screw Plate Systems in Stable Trochanteric Femur Fractures: A Biomechanical Evaluation. J Orthop Trauma 2012 Oct 30. [Epub ahead of print]
218. Colman M, Wright A, Gruen G, Siska P, Pape HC, Tarkin I. Prolonged operative time increases infection rate in tibial plateau fractures. Injury 2012 Nov 28. [Epub ahead of print]
219. Pfeifer R, Lichte P, Schreiber H, Sellei RM, Dienstknecht T, Sadeghi C, Pape HC, Kobbe P. Models of hemorrhagic shock: Differences in the physiological and inflammatory response. Cytokine 2012 Nov 21. [Epub ahead of print]
220. Knobe M, Gradl G, Ladenburger A, Tarkin IS, Pape HC. Unstable Intertrochanteric Femur Fractures: Is There a Consensus on Definition and Treatment in Germany? Clin Orthop Relat Res. 2013 Feb 7. [Epub ahead of print]
221. Zelle BA, Bhandari M, Sanchez AI, Probst C, Pape HC. Loss of follow-up in orthopaedic trauma: is 80% follow-up still acceptable? J Orthop Trauma 2013 Mar;27(3):177-81.
222. Pfeifer R, Darwiche S, Kohut L, Billiar TR, Pape HC. Cumulative Effects of Bone and Soft Tissue Injury on Systemic Inflammation: A Pilot Study.Clin Orthop Relat Res. 2013 Mar 12. [Epub ahead of print]
223. Lichte P, Sellei RM, Kobbe P, Dombroski DG, Gänsslen A, Pape HC. Predictors of poor outcome after both column acetabular fractures: a 30-year retrospective cohort study. Patient Saf Surg. 2013 Mar 19;7(1):9.
224. Dienstknecht T, Rixen D, Giannoudis P, Pape HC, the EPOFF Study Group. Do Parameters Used to Clear Noncritically Injured Polytrauma Patients for Extremity Surgery Predict Complications? Clin Orthop Relat Res. 2013 Mar 20. [Epub ahead of print]
225. Dienstknecht T, Pfeifer R, Horst K, Sellei RM, Berner A, Zelle BA, Probst C, Pape HC. The long-term clinical outcome after pelvic ring injuries. Bone Joint J. 2013 Apr 1;95-B(4):548-53.
226. Pfeifer R, Tschernig T, Lichte P, Dombroski D, Kobbe P, Pape HC. MALP-2 pre- treatment modulates systemic inflammation in hemorrhagic shock. J Inflamm (Lond). 2013 Apr 12;10(1):17. [Epub ahead of print]
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227. Dugan TR, Hubert MG, Siska PA, Pape HC, Tarkin IS. Open supracondylar femur fractures with bone loss in the polytraumatized patient - Timing is everything! Injury 2013 Apr 16.
228. Sellei RM, Schandelmaier P, Kobbe P, Knobe M, Pape HC. Can a Modified Anterior External Fixator Provide Posterior Compression of AP Compression Type III Pelvic Injuries? Clin Orthop Relat Res. 2013 Apr 19. [Epub ahead of print]
229. Garving C, Dienstknecht T, Horst K, Pishnamaz M, Kobbe P, Pape HC. Traumatic bilateral posterior dislocation of the shoulder: a case report. Cent Eur J Med. 2013;8(6): 810-813 (Impact(2012)=0.262)
230. Horst K, Dienstknecht T, Pishnamaz M, Kobbe P, Sellei RM, Pape HC. Upper ankle ligament rupture and long term problems in a patient with Ehlers Danlos Syndrome - a case report. Cent Eur J Med. 2013;8(6): 814-817 (Impact(2012)=0.262)
231. Brand RA, Pape HC. Biographical sketch: Harald Tscherne, MD (1933-present). Clin Orthop Relat Res. 2013;471(9): 2753-4 (Impact(2012)=2.787)
232. Dienstknecht T, Rixen D, Giannoudis P, Pape HC, EPOFF Study Group , Gruner A, Oestern HJ, Dumont C, Mueller M, Bouillon B, Rixen D, Morley J, Ruchholtz S, Ellingsen E, Regel G, McClinsey M. Do parameters used to clear noncritically injured polytrauma patients for extremity surgery predict complications? Clin Orthop Relat Res. 2013;471(9): 2878-84 (Impact(2012)=2.787)
233. Knobe M, Gradl G, Ladenburger A, Tarkin IS, Pape HC. Unstable intertrochanteric femur fractures: is there a consensus on definition and treatment in Germany? Clin Orthop Relat Res. 2013;471(9): 2831-40 (Impact(2012)=2.787)´
234. Fayaz HC, Haas N, Kellam J, Bavonratanavech S, Parvizi J, Dyer G, Pohlemann T, Jerosch J, Prommersberger KJ, Pape HC, Smith M, Vrahas M, Perka C, Siebenrock K, Elhassan B, Moran C, Jupiter JB. Improvement of research quality in the fields of orthopaedics and trauma: a global perspective. Int Orthop. 2013;37(7): 1205-12 (Impact(2012)=2.319)
235. Sturm JA, Pape HC, Dienstknecht T. Trauma care in Germany: an inclusive system. Clin Orthop Relat Res. 2013;471(9): 2912-23 (Impact(2012)=2.787)
236. Thormann U, Erli HJ, Brügmann M, Szalay G, Schlewitz G, Pape HC, Schnettler R, Alt V. Association of clinical parameters of operatively treated thoracolumbar fractures with quality of life parameters. Eur Spine J. 2013;22(10): 2202-10 (Impact(2012)=2.133)
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237. Colman M, Wright A, Gruen G, Siska P, Pape HC, Tarkin I. Prolonged operative time increases infection rate in tibial plateau fractures. Injury 2013;44(2): 249-52 (Impact(2012)=2.174)
238. Dugan TR, Hubert MG, Siska PA, Pape HC, Tarkin IS. Open supracondylar femur fractures with bone loss in the polytraumatized patient - Timing is everything! Injury 2013;44(12): 1826-31 (Impact(2012)=2.174)
239. Kobbe P, Micansky F, Lichte P, Sellei RM, Pfeifer R, Dombroski D, Lefering R, Pape HC, TraumaRegister DGU. Increased morbidity and mortality after bilateral femoral shaft fractures: myth or reality in the era of damage control? Injury 2013;44(2): 221-5 (Impact(2012)=2.174)
240. Gradl G, Knobe M, Stoffel M, Prescher A, Dirrichs T, Pape HC. Biomechanical evaluation of locking plate fixation of proximal humeral fractures augmented with calcium phosphate cement. J Orthop Trauma 2013;27(7): 399-404 (Impact(2012)=1.751)
241. Schmidt-Rohlfing B, Heussen N, Knobe M, Pfeifer R, Kaneshige JR, Pape HC. Reoperation rate after internal fixation of intertrochanteric femur fractures with the percutaneous compression plate: what are the risk factors? J Orthop Trauma 2013;27(6): 312-7 (Impact(2012)=1.751)
242. Zelle BA, Bhandari M, Sanchez AI, Probst C, Pape HC. Loss of follow-up in orthopaedic trauma: is 80% follow-up still acceptable? J Orthop Trauma 2013;27(3): 177-81 (Impact(2012)=1.751)
243. Hildebrand F, Andruszkow H, Huber-Lang M, Pape HC, van Griensven M. Combined hemorrhage/trauma models in pigs-current state and future perspectives. Shock 2013;40(4): 247-73 (Impact(2012)=2.612)
244. Andruszkow H, Pape HC, Sellei R, Hildebrand F. Prognosis of polytraumatized patients: estimates in the shock room and intensive care station]. Unfallchirurg 2013;116(5): 451-64 (Impact(2012)=0.64)
245. Loosen S, Preuss S, Zelle BA, Pape HC, Tarkin IS. Multimorbid patients with poor soft tissue conditions: treatment of distal tibia fractures with retrograde intramedullary nailing]. Unfallchirurg 2013;116(6): 553-8 (Impact(2012)=0.64)
246. Horst K, Dienstknecht T, Sellei RM, Pape HC. Partial rupture of the hamstring muscle complex: a literature review on treatment options. Eur J Orthop Surg Traumatol. 2013 Sep 29
247. Michalewicz E, Pape HC. Adult respiratory distress syndrome induced by blunt trauma-A dying threat throughout the world? Injury 2014 Apr;45(4):643-4.
248. Horst K, Von Harten R, Weber C, Andruszkow H, Pfeifer R, Dienstknecht T, Pape HC. Assessment of coincidence and defect sizes in Bankart and Hill-Sachs lesions
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after anterior shoulder dislocation: a radiological study. Br J Radiol. 2014 Feb;87(1034).
249. Horst K, Dienstknecht T, Andruszkow H, Gradl G, Kobbe P, Pape HC. Radiographic changes in the operative treatment of acute acromioclavicular joint dislocation - tight rope technique vs. K-wire fixation. Pol J Radiol. 2013 Oct;78(4):15-20.
250. Garving C, Santosa D, Bley C, Pape HC. Kostenanlyse von Schockraumpatienten im DRG-System. Unfallchirurg 2013; doi 10.1007/s00113-013-2405-2.
251. Kobbe P, Pishnamaz M, Lange H, Pape HC. Minimally invasive dorsal stabilization of traumatic thoracolumbar instabilities. Operative Techniques in Orthopaedics 2013 March; 23;13-18.
252. Sellei RM, Dienstknecht T, Brücken D, Pfeifer R, Pape HC. Percuntaneous Anterior Internal Pelvic Fixator. Operative Techniques in Orthopaedics 2013 March; 23:33-37.
253. Horst K, Dienstknecht T, Pfeifer R, Pishnamaz M, Hildebrand F, Pape HC. Risk stratification by injury distribution in polytrauma patients – does the clavicular fracture play a role? Patient Saf Surg. 2013 Jul 4;7:23.
254. Darwiche SS, Ruan X, Hoffman MK, Zettel KR, Tracy AP, Schroeder LM, Cai C, Hoffman RA, Scott MJ, Pape HC, Billiar TR. Selective roles for toll-like receptors 2, 4, and 9 in systemic inflammation and immune dysfunction following peripheral tissue injury. J Trauma Acute Care Surg. 2013 Jun;74(6):1454-61.
255. Kobbe P, Pishnamaz M, Pape HC, Schnake KJ. Thoracoscopic Vertebral Body Replacement in Spinal Trauma. Operative Techniques in Orthopaedics 2013 March; 23:19-27.
256. Hildebrand F, Andruszkow H, Barkatali B, Lichte RP, Kobbe P, Pape HC. Animal models to assess the local and systemic effects of nailing: Review of the literature and considerations for future studies. J Trauma Acute Care Surg. 2014 Jun;76(6):1495-506.
257. 257. Lichte P, Pfeifer R, Werner BE, Ewers P, Tohidnezhad M, Pufe T, Hildebrand F, Pape HC, Kobbe P. Dehydroepiandrosterone modulates the inflammatory response in a bilateral femoral shaft fracture model. Eur J Med Res. 2014 May 19;19:27.
258. Fröhlich M, Hildebrand F, Weuster M, Mommsen P, Mohr J, Witte I, Raeven P, Ruchholtz S, Flohé S, van Griensven M, Pape HC, Pfeifer R. Induced hypothermia reduces the hepatic inflammatory response in a swine multiple trauma model. J Trauma Acute Care Surg. 2014 Jun;76(6):1425-32.
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259. Garving C, Weber CD, Poßelt S, Pishnamaz M, Pape HC, Dienstknecht T. Kosten- Nutzen-Analyse der Schnittbildgebung beim leichten Schädel-Hirn-Trauma – Wie sachgerecht ist die Abbildung im G‑DRG-System? Z Orthop Unfall 2014; 152(3): 224-229.
260. Pape D, Pape HC. Osteoporotische gelenknahe und periprothetische Frakturen im hohen Lebensalter. Der Orthopäde 2014 April; 43:297.
261. Andruskzkow H, Haasper C, Lob G, Pfeifer R, Stengel D, Hildebrand F, Pape HC. Status of Road Safety and Injury Burden: Europe. Journal of Orthopaedic Trauma 2014 June; 28:39-40.
262. Sellei RM, Andruszkow H, Weber C, Damen TO, Pape HC, Hildebrand F. Diagnostik und Therapieentscheidung beim akuten Kompartmentsyndrom. Unfallchirurg 2014 Juli.
263. Sellei RM, Hildebrand F, Pape HC. Das akute Kompartmentsyndrom der Extremitäten. Unfallchirurg 2014 Juli; Vol 117; 7:633-649.
264. 264. Sellei RM, Kobbe P, Dienstknecht T, Lichte P, Pfeifer R, Behrens M, Brianza S, Pape HC. Biomechanical properties of different external fixator frame configurations. Eur J Trauma Emerg Surg 2014 August;10.1007/s00068-014-0436- 1.
265. Gänsslen A, Gösling T, Hildebrand F, Pape HC, Oestern HJ. Femoral shaft fractures in adults: treatment options and controversies. Acta Chir Orthop Traumatol Cech 2014;81(2):108-17.
266. Andruszkow H, Pfeifer R, Horst K, Kobbe P, Pape HC, Hildebrand F. Biomarker beim kindlichen Polytrauma. Unfallchirurg 2014 August;117(8):679-85.
267. Andruszkow H, Hildebrand F, Lefering R, Pape HC, Hoffmann R, Schweigkofler U. Ten years of helicopter emergency medical services in Germany: Do we still need the helicopter rescue in multiple traumatised patients? Injury 2014 Oct;45 Suppl 3:S53-8.
268. Lichte P, Weber C, Sellei RM, Hildebrand F, Lefering R, Pape HC, Kobbe P; TraumaRegister DGU. Are bilateral tibial shaft fractures associated with an increased risk for adverse outcome? Injury 2014 Dec;45(12):1985-9.
269. Horst K, Hildebrand F, Pfeifer R, Köppen K, Lichte P, Pape HC, Dienstknecht T. Plate osteosynthesis versus hemiarthroplasty in proximal humerus fractures--does routine screening of systemic inflammatory biomarkers makes sense? Eur J Med Res. 2015 Jan 14;20:5.
270. Hildebrand F, Radermacher P, Ruchholtz S, Huber-Lang M, Seekamp A, Flohé S, van Griensven M, Andruszkow H, Pape HC. Relevance of induced and accidental
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hypothermia after trauma-haemorrhage-what do we know from experimental models in pigs? Intensive Care Med Exp. 2014 Dec;2(1):16.
271. Hildebrand F, Pape HC. What's new in Shock, January 2015? Shock 2015 Jan;43(1):1-2.
272. Horst K, Eschbach D, Pfeifer R, Hübenthal S, Sassen M, Steinfeldt T, Wulf H, Ruchholtz S, Pape HC, Hildebrand F. Local inflammation in fracture hematoma: results from a combined trauma model in pigs. Mediators Inflamm. 2015;2015:126060.
273. Sellei RM, Hingmann SJ, Kobbe P, Weber C, Grice JE, Zimmerman F, Jeromin S, Hildebrand F, Pape HC. Compartment elasticity measured by pressure-related ultrasound to determine patients "at risk" for compartment syndrome: an experimental in vitro study. Patient Saf Surgery 2015 Jan 24;9(1):4.
274. 274. Hofman M, Koopmans G, Kobbe P, Poeze M, Andruszkow H, Brink PR Pape HC. Improved fracture healing in patients with concomitant traumatic brain injury: proven or not? Mediators Inflamm. 2015;2015:204842.
275. Gradl G, Knobe M, Pape HC, Neuhaus PV, Ring D, Guitton T. Is percutaneous suturing superior to open fibrin gluing in acute Achilles tendon rupture? Int Orthop. 2015 Mar;39(3):535-42.
276. Horst K, Hildebrand F, Pfeifer R, Hübenthal S, Almahmoud K, Sassen M, Steinfeldt T, Wulf H, Ruchholtz S, Pape HC, Eschbach D. Impact of haemorrhagic shock intensity on the dynamic of alarmins release in porcine poly-trauma animal model. Eur J Trauma Emerg Surg. 2015 Feb 28.
277. Jabakhanji SB, Meier TM, Ramakers-van Kuijk MA, Brink PR, Andruszkow H, Krafft T, Pape HC. Agreements and practical experience of trauma care cooperation in Central Europe: the "Boundless Trauma Care Central Europe" (BTCCE) project. Injury 2015 Apr;46(4):519-24.
278. Lichte P, Kobbe P, Almahmoud K, Pfeifer R, Andruszkow H, Hildebrand F, Lefering R, Pape HC; Trauma Register DGU. Post-traumatic thrombo-embolic complications in polytrauma patients. Int Orthop. 2015 May;39(5):947-54.
279. Sellei RM, Bauer E, Hofman M, Kobbe P, Lichte P, Garrison RL, Pape HC, Horst K. Reconstruction of a quadriceps tendon tear using Polyvinylidene fluoride sutures and patellar screw fixation: A biomechanical study. Knee 2015 May 21.
280. Sellei RM, Kobbe P, Dienstknecht T, Lichte P, Pfeifer R, Behrens M, Brianza S, Pape HC. Biomechanical properties of different external fixator frame configurations. Eur J Trauma Emerg Surg. 2015 Jun;41(3):313-8.
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281. Pfeifer R, Andruszkow JH, Busch D, Hoepken M, Barkatali BM, Horst K, Pape HC, Hildebrand F. Development of a standardized trauma-related lung injury model. Journal of Surg Res. 2015 Jun 15;196(2):388-94
282. Lichte P, Kobbe P, Pfeifer R, Campbell GC, Beckmann R, Tohidnezhad M, Bergmann C, Kadyrov M, Fischer H, Glüer CC, Hildebrand F, Pape HC, Pufe T. Impaired Fracture Healing after Hemorrhagic Shock. Mediators Inflamm. 2015;2015:132451.
283. Lichte P, Pfeifer R, Kobbe P, Tohidnezhad M, Pufe T, Almahmoud K, Hildebrand F, Pape HC. Inhalative IL-10 treatment after bilateral femoral fractures affect pulmonary inflammation in mice. Annals of Anatomy 2015 Jul;200:73-8.
284. Lichte P, Andruszkow H, Kappe M, Horst K, Pishnamaz M, Hildebrand F, Lefering R, Pape HC, Kobbe P; TraumaRegister DGU. Increased in-hospital mortality following severe head injury in young children: results from a nationwide trauma registry. Eur J Med Res. 2015 Aug 14;20:65.
285. Gradl G, Bühren A, Simon M, Derntl B, Pape HC, Knobe M. Bootcamp – Longitudinaler „Skills-Kurs“ zur Vermittlung klinischer und operativer Fertigkeiten. Unfallchirurg. 2015 Aug 5.
286. Hildebrand F, Pape HC, Horst K, Andruszkow H, Kobbe P, Simon TP, Marx G, Schürholz T. Impact of age on the clinical outcomes of major trauma. Eur J Trauma Emerg Surg. 2015 Aug 8.
287. Pishnamaz M, Dienstknecht T, Hoppe B, Garving C, Lange H, Hildebrand F, Kobbe P, Pape HC. Assessment of pelvic injuries treated with ilio-sacral screws: injury severity and accuracy of screw positioning. Int Orthop. 2015 Aug 11.
288. Knobe M, Gradl G, Buecking B, Gackstatter S, Sönmez TT, Ghassemi A, Stromps JP, Prescher A, Pape HC. Locked minimally invasive plating versus fourth generation nailing in the treatment of AO/OTA 31A2.2 fractures: A biomechanical comparison of PCCP(®) and Intertan nail(®). Injury 2015 Aug;46(8):1475-82.
289. Herren C, Weber CD, Pishnamaz M, Dienstknecht T, Kobbe P, Hildebrand F, Pape HC. Fracture of the lesser trochanter as a sign of undiagnosed tumor disease in adults. Eur J Med. Res. 2015 Sep 4;20:72.
290. Eschbach D, Steinfeldt T, Hildebrand F, Frink M, Schöller K, Sassen M, Wiesmann T, Debus F, Vogt N, Uhl E, Wulf H, Ruchholtz S, Pape HC, Horst K. A porcine polytrauma model with two different degrees of hemorrhagic shock: outcome related to trauma within the first 48 h. Eur J Med Res 2015 Sep 4;20:73.
291. Sellei RM, Hingmann SJ, Kobbe P, Weber C, Grice JE, Zimmerman F, Jeromin S, Gansslen A, Hildebrand F, Pape HC. Measurement of compartment elasticity using pressure related ultrasound: a method to identify patients with potential compartment syndrome. Acta Chir Orthop Traumatol Cech. 2015;82(3):198-202.
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292. Wollgarten M, Keel MJ, Pape HC. Editorial: Emergency fixation of the pelvic ring using the pelvic C clamp - has anything changed? Injury 2015 Sept: 46 Suppl 3:13- 8.
293. Horst K, Andruszkow H, Weber C, Dienstknecht T, Hildebrand F, Tarkin I, Pape HC. Standards of external fixation in prolonged applications to allow safe conversion to definitive extremity surgery: the Aachen algorithm for acute ex fix conversion. Injury 2015 Sept;46 Suppl 3:13-8.
294. Sellei RM, Kobbe P, Dadgar A, Pfeifer R, Behrens M, von Oldenburg G, Pape HC. External fixation design evolution enhances biomechanical frame performance. Injury 2015 September;46 Suppl 3:23-6.
295. Andruszkow H, Pfeifer R, Horst K, Hildebrand F, Pape HC. External fixation in the elderly. Injury 2015 September; 46 Suppl 3:7-12.
296. Herren C, Pishnamaz M, Lichte P, Hildebrand F, Sellei RM, Pape HC, Kobbe P. Die ventrale „Triple-/Quadruple“-Schraubenosteosynthese für die traumatische C1– C2-Kombinationsverletzung des geriatrischen Patienten: erste operative Erfahrungen mit 16 Patienten. Z Orthop Unfall. 2015 Oct;153(5):533-9.
297. Hildebrand F, Lefering R, Andruszkow H, Zelle BA, Barkatali BM, Pape HC. Development of a scoring system based on conventional parameters to assess polytrauma patients: PolyTrauma Grading Score (PTGS). Injury 2015 Oct;46 Suppl. 4:93-8.
298. Marx G, Beckers R, Brokmann JC, Deisz R, Pape HC. Telekooperation für die innovative Versorgung am Beispiel des Universitätsklinikums Aachen. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2015 Oct;58(10):1056-61.
299. Pishnamaz M, Oikonomidis S, Knobe M, Horst K, Pape HC, Kobbe P. Open versus Percutaneous Stabilization of Thoracolumbar Spine Fractures: A Short-Term Functional and Radiological Follow-up. Acta Chir Orthop Traumatol Cech 2015;82(4):274-281.
300. Pishnamaz M, Curfs I, Balosu S, Willems P, van Hemert W, Pape HC, Kobbe P. Two-Nation Comparison of Classification and Treatment of Thoracolumbar Fractures: An Internet-Based Multicenter Study among Spine Surgeons. Spine 2015 Oct 17.
301. Pishnamaz M, Lichte P, Sellei RM, Pape HC, Kobbe P. Perkutane dorsale Stabilisierung der Brust- und Lendenwirbelsäule mit aktiver intraoperativer Repositionsmöglichkeit. Oper Orthop Traumatology 2015 Oct;27(5):439-47.
302. Weber CD, Horst K, Lefering R, Hofman M, Dienstknecht T, Pape HC; TraumaRegister DGU. Major trauma in winter sports: an international trauma database analysis. European Journal Trauma Emergeny Surgery. 2015 Nov.
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303. Griensven M, Huber-Lang M, Flohe SB, Andruszkow H, Marzi I, Pape HC, Trauma Research Network of the German Society of Trauma, DGU. Is there an impact of Concomitant Injuries and Timing of Fixation of Major Fractures on Fracture Healing? A Focused Review of Clinical and Experimental Evidence. Journal of Orthopaedic Trauma 2015 Nov.
304. Egol KA, Nauth A, Lee M, Pape HC, Watson JT, Borrelli J Jr. Bone Grafting: Sourcing, Timing, Strategies, and Alternatives. Journal of Orthopaedic Trauma 2015 Dec;29 Suppl 12: 10-4.
305. Horst K, Hildebrand F, Kobbe P, Pfeifer R, Lichte P, Andruszkow H, Lefering R, Pape HC. Detecting severe injuries of the upper body in multiple trauma patients. J Surg Res. 2015 Dec;199(2):629-34.
306. Sellei RM, Hingmann SJ, Weber C, Jeromin S, Zimmermann F, Turner J, Hildebrand F, Pape HC. Assessment of elevated compartment pressures by pressure-related ultrasound: a cadaveric model. Eur J Trauma Emerg Surg. 2015 Dec;41(6):639-45.
307. Lichte P, Pape HC. Ursachengerechte Therapie der posttraumatischen Kniegelenksteife. Trauma und Berufskrankheit 2015 Dec.
308. Andruszkow H, Schweigkofler U, Lefering R, Frey M, Horst K, Pfeifer R, Beckers SK, Pape HC, Hildebrand F. Impact of Helicopter Emergency Medical Service in Traumatized Patients: Which Patient Benefits Most? PLoS One. 2016 Jan 15;11(1):e0146897.
309. Pfeifer R, Pape HC. Diagnostik und Versorgungsstrategien beim polytraumatisierten Patienten. Der Chirurg. 2016 Jan 30
310. Knobe M, Nagel P, Maier KJ, Gradl G, Buecking B, Sönmez TT, Modabber A, Prescher A, Pape HC. Rotationally Stable Screw-Anchor With Locked Trochanteric Stabilizing Plate Versus Proximal Femoral Nail Antirotation in the Treatment of AO/OTA 31A2.2 Fracture: A Biomechanical Evaluation. J Orthop Trauma. 2016 Jan;30(1):e12-8.
311. Pishnamaz M, Wilkmann C, Na HS, Pfeffer J, Hänisch C, Janssen M, Bruners P, Kobbe P, Hildebrand F, Schmitz-Rode T, Pape HC. Electromagnetic Real Time Navigation in the Region of the Posterior Pelvic Ring: An Experimental In-Vitro Feasibility Study and Comparison of Image Guided Techniques. PLoS One. 2016 Feb 10;11(2):e0148199.
312. Pfeifer R, Teuben M, Andruszkow H, Barkatali BM, Pape HC. Mortality Patterns in Patients with Multiple Trauma: A Systematic Review of Autopsy Studies. PLoS One 2016 Feb 12;11(2):e0148844.
313. Pastor T, Gradl G, Klos K, Ganse B, Horst K, Andruszkow H, Hildebrand F, Pape HC, Knobe M. Displaced intra-articular calcaneal fractures: is there a consensus on
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treatment in Germany? International Orthopaedics 2016 Feb 22. [Epub ahead of print]
314. Kohmann D, Lüttjohann A, Seidenbecher T, Coulon P, Pape HC. Short term depression of gap junctional coupling in reticular thalamic neurons of absence epileptic rats. J Physiol. 2016 Mar 4.
315. Metsemakers WJ, Moriarty TF, Nijs S, Pape HC, Richards RG. Influence of implant properties and local delivery systems on the outcome in operative fracture care. Injury. 2016 Mar;47(3):595-604.
316. Gradl-Dietsch G, Korden T, Modabber A, Sönmez TT, Stromps JP, Ganse B, Pape HC, Knobe M. Multidimensional approach to teaching anatomy-Do gender and learning style matter? Anatomischer Anzeiger. 2016 Mar 28.
317. Hildebrand F, van Griensven M, Huber-Lang M, Flohe SB, Andruszkow H, Marzi I, Pape HC; Trauma Research Network of the German Society of Trauma, DGU. Is There an Impact of Concomitant Injuries and Timing of Fixation of Major Fractures on Fracture Healing? A Focused Review of Clinical and Experimental Evidence. J Orthop Trauma. 2016 Mar;30(3):104-12.
318. Horst K, Eschbach D, Pfeifer R, Relja B, Sassen M, Steinfeldt T, Wulf H, Vogt N, Frink M, Ruchholtz S, Pape HC, Hildebrand F. Long-Term Effects of Induced Hypothermia on Local and Systemic Inflammation - Results from a Porcine Long- Term Trauma Model. PLoS One. 2016 May 4;11(5):e0154788.
319. Herren C, Dienstknecht T, Siewe J, Kobbe P, Pape HC, Hildebrand F. Die Chronische Symphyseninstabilität; Ätiologie, Diagnostik und Behandlungs- management. Unfallchirurg. 2016 May;119(5):433-46.
320. Herren C, Dienstknecht T, Siewe J, Kobbe P, Pape HC, Hildebrand F. Operative Versorgung der Symphysensprengung. Unfallchirurg. 2016 May;119(5):433-46.
321. Ganse B, Yang PF, Gardlo J, Gauger P, Kriechbaumer A, Pape HC, Koy T, Müller LP, Rittweger J. Partial weight bearing of the tibia. Injury. 2016 Aug;47(8):1777-82.
322. Hildebrand F, Pape HC. What is New in Shock, August 2016? Shock. 2016 Aug;46(2):111-2.
323. Weber CD, Herren C, Dienstknecht T, Hildebrand F, Keil S, Pape HC, Kobbe P. Management of Life-Threatening Arterial Hemorrhage Following a Fragility Fracture of the Pelvis in the Anticoagulated Patient: Case Report and Review of the Literature. Geriatr Orthop Surg Rehabil. 2016 Sep;7(3):163-7.
324. Knobe M, Giesen M, Plate S, Gradl-Dietsch G, Buecking B, Eschbach D, van Laack W, Pape HC. The Aachen Mobility and Balance Index to measure physiological falls risk: a comparison with the Tinetti POMA Scale. Eur J Trauma Emerg Surg. 2016 Oct;42(5):537-545.
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325. Weber CD, Lefering R, Dienstknecht T, Kobbe P, Sellei RM, Hildebrand F, Pape HC, TraumaRegister DGU. Classification of soft-tissue injuries in open femur fractures: Relevant for systemic complications? Journal of Trauma Acute Care Surgery. 2016 November;82(5):824-833.
326. Weber CD, Lefering R, Dienstknecht T, Kobbe P, Sellei RM, Hildebrand F, Pape HC, TraumaRegister DGU. Classification of soft-tissue injuries in open femur fractures: Relevant for systemic complications? Journal of Trauma Acute Care Surgery. 2016 November;82(5):824-833.
327. Almahmoud K, Teuben M, Andruszkow H, Horst K, Lefering R, Hildebrand F, Pape HC, Pfeifer R. Trends in intubation rates and durations in ventilated severely injured trauma patients: an analysis from the TraumaRegister DGU®. Patient Safety Surgery. 2016 Nov 3;10:24.
328. Knobe M, Pape HC. Co-management in geriatric hip fractures. European Journal of Trauma Emergeny Surgery. 2016 Dec;42(6):795-796.
329. Thaeter M, Knobe M, Vande Kerckhove M, Böhle F, Herold J, Verhaven E, Pape HC. Perioperative inflammatory response in major fracture: do geriatric patients behave differently? Journal of Trauma Acute Care Surgery. 2016 Dec;42(5):547- 551
330. Horst K, Simon TP, Pfeifer R, Teuben M, Almahmoud K, Zhi Q, Santos SA, Wembers CC, Leonhardt S, Heussen N, Störmann P, Auner B, Relja B, Marzi I, Haug AT, van Griensven M, Kalbitz M, Huber-Lang M, Tolba R, Reiss LK, Uhlig S, Marx G, Pape HC, Hildebrand F. Characterization of blunt chest trauma in a long-term porcine model of severe multiple trauma. Sci Rep. 2016 Dec 21;6:39659.
331. Gradl G, Bühren A, Simon M, Derntl B, Pape HC, Knobe M. Bootcamp – Longitudinaler „Skills-Kurs“ zur Vermittlung klinischer und operativer Fertigkeiten. Unfallchirurg. 2017 Jan;120(1):46-54.
332. Mauffrey C, Giannoudis P, Civil I, Gray AC, Roberts C, Pape HC, Evans C, Kool B, Mauffrey OJ, Stengel D. Pearls and pitfalls of open access: The immortal life of Henrietta Lacks. Injury. 2017 Jan;48(1):1-2.
333. Weber CD, Kobbe P, Herren C, Mahnken AH, Hildebrand F, Pape HC. Endovascular Management of a Combined Subclavian and Vertebral Artery Injury in an Unstable Polytrauma Patient: Case Report and Literature Review. Bull Emerg Trauma. 2017 Jan;5(1):53-57.
334. Almahmoud K, Pfeifer R, Al-Kofahi K, Hmedat A, Hyderabad W, Hildebrand F, Peitzman AB, Pape HC. Impact of pelvic fractures on the early clinical outcomes of severely injured trauma patients. Eur J Trauma Emerg Surg. 2017 Jan 13.
335. Fang C, Alabdulrahman H, Pape HC. Complications after percutaneous internal fixator for anterior pelvic ring injuries. Int Orthop. 2017 Feb 24.
49 Curriculum Vitae, HC Pape MD, FACS
336. Jentzsch T, Pothmann C, Sprengel K, Alkadhi H, Simmen HP, Pape HC. Paradigm shifts in diagnostics and treatment of multiply injured patients - How does it affect visceral injuries? Injury. 2017 Mar;48(3):565-567.
337. Horst K, Garving C, Thometzki T, Lichte P, Knobe M, Dienstknecht T, Hofman M, Pape HC. Comparative study on the treatment of Rockwood type III acute acromioclavicular dislocation: clinical results from the Tight Rope® technique vs. K-wire fixation. Orthopaedics & Traumatology: Surgery & Research. 2017 Apr.
338. Herren C, Beckmann A, Meyer S, Pishnamaz M, Mundt M, Sobottke R, Prescher A, Stoffel M, Markert B, Kobbe P, Pape HC, Eysel P, Siewe J. Biomechanical testing of a PEEK-based dynamic instrumentation device in a lumbar spine model. Clin Biomech (Bristol, Avon). 2017 May 18;44:67-74.
339. Gombert A, Barbati ME, Storck M, Kotelis D, Keschenau P, Pape HC, Andruszkow H, Lefering R, Hildebrand F, Greiner A, Jacobs MJ, Grommes J. Treatment of blunt thoracic aortic injury in Germany-Assessment of the TraumaRegister DGU®. PLoS One. 2017 Mar 27;12(3):e0171837.
340. Remmers F, Lange MD, Hamann M, Ruehle S, Pape HC, Lutz B. Addressing sufficiency of the CB1 receptor for endocannabinoid-mediated functions through conditional genetic rescue in forebrain GABAergic neurons. Brain Struct Funct. 2017 Apr 9.
341. Fixation using Alternative Implants for the Treatment of Hip fractures (FAITH) Investigators. Fracture fixation in the operative management of hip fractures (FAITH): an international, multicentre, randomised controlled trial. Lancet. 2017 Apr 15;389(10078):1519-1527.
342. Blokhuis TJ, Pape HC, Frölke JP. Timing of definitive fixation of major long bone fractures: Can fat embolism syndrome be prevented? Injury. 2017 Apr 24.
343. Beckmann A, Herren C, Mundt M, Siewe J, Kobbe P, Sobottke R, Pape HC, Stoffel M, Markert B. A new in vitro spine test rig to track multiple vertebral motions under physiological conditions. Biomed Tech (Berl). 2017 Apr 27.
344. Rasche P, Mertens A, Bröhl C, Theis S, Seinsch T, Wille M, Pape HC, Knobe M. The "Aachen fall prevention App" - a Smartphone application app for the self- assessment of elderly patients at risk for ground level falls. Patient Safety Surgery 2017 May 8;11:14.
345. Tonglet M, Lefering R, Minon JM, Ghuysen A, D'Orio V, Hildebrand F, Pape HC, Horst K. Prehospital identification of trauma patients requiring transfusion: results of a retrospective study evaluating the use of the trauma induced coagulopathy clinical score (TICCS) in 33,385 patients from the TraumaRegister DGU®. Acta Chir Belg. 2017 Jun 22:1-6.
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346. Liu X, Si W, Garau C, Jüngling K, Pape HC, Schulz S, Reinscheid RK. Neuropeptide S precursor knockout mice display memory and arousal deficits. Eur J Neurosci. 2017 Jul;46(1):1689-1700.
347. Greven J, Pfeifer R, Zhi Q, Pape HC. Update on the role of endothelial cells in trauma. Eur J Trauma Emerg Surg. 2017 Jul 3.
348. Fang C, Alabdulrahman H, Pfeifer R, Tarkin IS, Pape HC. Late reconstruction of severe open-book deformities of the pelvis - tips and tricks. Int Orthop. 2017 Jul 5.
349. Pfeifer R, Schick S, Holzmann C, Graw M, Teuben M, Pape HC. Analysis of Injury and Mortality Patterns in Deceased Patients with Road Traffic Injuries: An Autopsy Study. World J Surg. 2017 Jul 17.
350. Santos SA, Wembers CC, Horst K, Pfeifer R, Simon TP, Pape HC, Hildebrand F, Czaplik M, Leonhardt S, Teichmann D. Monitoring lung contusion in a porcine polytrauma model using EIT: an application study. Physiol Meas. 2017 Jul 26;38(8):1542-1560.
351. Stengel D, Mauffrey C, Civil I, Gray AC, Roberts C, Pape HC, Evans C, Kool B, Mauffrey OJ, Giannoudis P. Recruitment rates in orthopaedic trauma trials: Zen or the art of riding dead horses. Injury. 2017 Aug;48(8):1719-1721.
352. Weber CD, Nguyen AR, Lefering R, Hofman M, Hildebrand F, Pape HC. Blunt injuries related to equestrian sports: results from an international prospective trauma database analysis. Int Orthop. 2017 Aug 11.
353. Scherer J, Guy P, Lefaivre KA, Pape HC, Werner CML, Osterhoff G. Guide wire insertion for percutaneous LC2 screws in acetabular and pelvic ring fixation using a transpedicular working cannula. Injury. 2017 Aug 25.
354. Pfeifer R, Heussen N, Michalewicz E, Hilgers RD, Pape HC. Incidence of adult respiratory distress syndrome in trauma patients: A systematic review and meta- analysis over a period of three decades. J Trauma Acute Care Surg. 2017 Sep;83(3):496-506.
355. Weber CD, Horst K, Nguyen AR, Bader MJ, Probst C, Zelle B, Pape HC, Dienstknecht T. Return to Sports After Multiple Trauma: Which Factors Are Responsible?-Results From a 17-Year Follow-up. Clin J Sport Med. 2017 Sep;27(5):481-486.
Book Chapters
51 Curriculum Vitae, HC Pape MD, FACS
1. Pape HC, Kant K. Study protocol. In: Sturm J.A. (Ed.): Adult Respiratory Distress Syndrome Springer Verlag 1991, 7-10.
2. Pape HC, Regel G, Kleemann W, Tscherne H. Multiorganversagen und Kapillarschaden beim Polytrauma - eine klinische und pathomorphologische Untersuchung. In: Hörl M. (Ed.): Pathogenese der katabolen Stoffwechsellage beim chirurgischen Problempatienten Thieme Verlag 1992, 221-224.
3. Pape HC, Sturm JA, Regel G, Tscherne H. Auswirkungen der Oberschenkelmarknagelung nach schwerem Trauma auf die Lungenfunktion - klinische und experimentelle Ergebnisse. In: Wenda K, Ritter (Eds.): Neue Aspekte der Marknagelung Springer Verlag 1993, 30-34.
4. Pape HC, Regel G, Kleemann W, Sturm JA, Tscherne H. The pattern of organ failure following severe trauma - a postmortem study. In: Faist E., Meakins F. (Eds.): Host defense Dysfunction in Trauma, Shock and Sepsis Springer Verlag 1993, 823-829.
5. Pape HC, Dwenger A, Remmers D, Regel G, Tscherne H. Early organ sign – focusing on the development of delayed organ failure. In: Monduzzi Editore (S.p.A.) 1994, 579-584.
6. Remmers D, Pape HC, Dwenger A, Regel G, Tscherne H. Reticuloendothelial system function, mediator release and endotoxinemia after trauma. In: Monduzzi Editore (S.p.A) 1994, 649-654.
7. Pape HC, Regel G, Tscherne H. Pulmonary complications after intramedullary stabilization of the femur. In: Browner B. (Ed.): The Science and Practice of Intramedullary Nailing Williams and Wilkins Co. 1995, 77-88.
8. Pape HC, Regel G, Dwenger A, Krumm K, Krettek C, Sturm JA. Influence of different types of intramedullary nailing in patients with multiple trauma. Year Book of Surgery Mosby 1995, 33-39.
9. Pape HC, Regel G, Tscherne H. Pulmonary complications after intramedullary stabilization of the femur. In: B. Browner (Ed.): The Science of Intramedullary Nailing Williams & Wilkins 1996, 77-88.
10. Pape HC, Dwenger A, Remmers D, Regel G, Tscherne H. Increased gut permeability correlates with inflammatory response systems in multiple trauma patients. In: E. Faist, A.E. Baue, F.W. Schildberg (Eds.): The Immune Consequences of Trauma. Shock and Sepsis, Vol. I 1996, 905-909.
11. Grotz M, Regel G, Dwenger A, Pape HC, Hainer C, Vaske R, Tscherne H. Standardized sheep model for multiple organ failure (MOF) after severe trauma In: E. Faist, A.E. Baue, F.W. Schildberg (Eds.): The Immune Consequences of Trauma. Shock and Sepsis, Vol. II-1 1996, 217-221.
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12. Dwenger A, Grotz M, Pape HC, Hainer C, Schweitzer G, Regel G. Neutrophil function and lung injury in the standardized sheep model of MOF. In: E. Faist, A.E. Baue, F.W. Schildberg (Eds.): The Immune Consequences of Trauma. Shock and Sepsis, Vol. II-2 1996, 395-399.
13. Pape HC, Dwenger A, Remmers D, Regel G. Unreamed femoral nailing affects lung function impairment and increased inflammatory response in polytrauma patients. In: E. Faist, A.E. Baue, F.W. Schildberg (Eds.): The Immune consequences of Trauma. Shock and Sepsis, Vol. II-1 1996, 403-406.
14. Regel G, Lehmann U, Rickels E, Pohlemann T, Pape HC, Tscherne H. Pathophysiology, Management And Outcome After Multiple Trauma. In: G. Schlag, H. Redl, D.Traber (Eds): Shock, Sepsis, and Organ Failure Springer Verlag 1996, 229-262.
15. Pape HC. Systemische Auswirkungen der Oberschenkelmarknagelung beim Schwerverletzten. Hefte zu "Der Unfallchirurg": 264, pp. 1-130 (1997)
16. Pape HC, Bischoff W. Die Intensivstation In: Tscherne/Regel (Hrsg.): Trauma Management Kapitel 5. Springer Verlag 1997, 79-101.
17. Pape HC, Lehmann U, Grotz M. Posttraumatisches Management. In: Tscherne/Regel (Hrsg.): Trauma Management Kapitel 6. Springer Verlag 1997, 391- 402.
18. Pape HC, Bader A, Remmers D, Stalp M, Regel G. Effects of endotoxin in a newly developed 3-D hepatocyte / hepatic sinusoidal cell culture? In: Monduzzi (Ed.): The immune consequences of Trauma, Shock and Sepsis Monduzzi 1997, 533-534.
19. Pape HC, Leuver M, Zuzan O. Das Polytrauma. In: M. Leuver, T. Schürmeyer, H.Trappe, O.Zuzan (Eds.): Checkliste -Interdisziplinäre Intensivmedizin Springer Verlag 1999, 553-561.
20. Pape HC, Tscherne H. Early definitive fracture fixation in polytrauma advantages - pulmonary consequences. In: A.E. Baue, Fry, E. Faist (Eds.): SIRS, MODS and MOF Springer Verlag 2000, 279-290.
21. Regel G, Pape HC. Die Lungenkontusion In: Trentz/Tscherne (Hrsg.): Unfallchirurgie "Kopf- und Körperhöhlen" Kapitel 7. Springer Verlag 2001, 251- 272.
22. Pape HC. Nicht medikamentöse Maßnahmen In: Adams, A (Ed.): Analgesie, Sedierung und Anästhesie in der Notfallmedizin Kapitel 3.1. UniMed Verlag 2001, 36-38.
23. Grimme K, Pape HC. Disseminierte Gerinnungsaktivierung In: Martin, E. (Ed.) Fachübergreifende Aspekte der Hämostaseologie 2004.
53 Curriculum Vitae, HC Pape MD, FACS
24. Gänsslen A, Pape HC. Management of pelvic injuries. In: Giannoudis PV, Pape HC. (Eds.) Practical Procedures in Trauma Surgery: A Trainee’s Companion Greenwich Med. Media Ltd. In press 2005.
25. Adams HA, Baumann G, Cascorbi I, Ebener C, Emmel M, Geiger S, Janssens U, Klima U, Klippe HJ, Knoefel WT, Marx G, Müller-Werdan U, Pape HC, Piek J, Prange H, Roesner D, Roth B, Schürholz T, Standl T, Teske W, Vogt PM, Werner GS, Windolf J, Zander R, ZerkowskiHR. Pathophysiologie und Therapie des hypovolämischen Schocks. In: Deutsche Akademie für Anästhesiologische Fortbildung (Hrsg.): Refresher Course. Aktuelles Wissen für Anästhesisten Nr. 31, 16. - 19. April 2005, München. Ebelsbach: Diomed 2005; S. 1-20.
26. Pape HC, Giannoudis PV. The care of the multiply injured patient. In RB Bucholz, JD Heckman, C Court Brown (Eds.) Rockwood and Green`s Fractures in Adults 6th edition. Lippincott Williams and Wilkins 2006.
27. Pape HC, Bentley G. European Instructional Lectures, 10th EFORT Congress, Vienna, Austria, Springer, Heidelberg 2009, S. 67-75 (); ISBN 978-3-642-00965-5
28. Lichte P, Pape HC. Orthopaedic Knowledge Update 10 (02/2011), John Flynn, MD, Editor, AAOS ISBN/ISSN: 9780892037360, Chapter "Polytrauma Care", Seite 129-136 29. Pape HC, Sanders R, Borrelli J. The Poly-Traumatized Patient with Fractures, 2011, Springer Verlag, ISBN: 978-3-642-17985-3
54 Curriculum Vitae, HC Pape MD, FACS
Published Abstracts
1. Pape HC, Regel G, Nerlich ML, Sturm JA, Tscherne H. Pulmonale Komplikationen bei Polytraumapatienten mit Oberschenkel-Schaftfrakturen- Einfluss durch Operationsverfahren? Der Anästhesist 1989; 38: 344.
2. Pape HC, Regel G, Sturm JA, Tscherne H. Ist das akute Nierenversagen nach Polytrauma therapeutisch zu beeinflussen? Hefte zu "Unfallheilkunde" 1990; 212: 105-106.
3. Pape HC, Jonas M, Dwenger A, Schweitzer G, Regel G, Sturm JA. Influence of intramedullary femoral nailing on pulmonary capillary permeability, hemodynamics and cell functions after pulmonary injury in sheep. European Surgery Research 1990; 22(1): 88-89.
4. Pape HC, Regel G, Dwenger A, Sturm JA. Does additional lung injury and hemorrhagic shock aggravate lung damage from intramedullary femoral nailing in sheep? Circulatory Shock 1990; 31(1): 54.
5. Pape HC, Dwenger A, Schweitzer G, Sturm JA. The influence of primary intramedullary femoral nailing on lung hemodynamics and functions of the nonspecific immune system in polytraumatized patients. European Surgery Research 1991; 23(1): 67-68.
6. Pape HC, Dwenger A, Schweitzer G, Sturm JA. Pulmonary damage after recurrent administration of Endotoxin or Endotoxin and Zymosan activated plasma - a sheep model X. Circulatory Shock 1991; 34-1: 66.
7. Pape HC, Regel G, Sturm JA, Tscherne H. Is there a pattern of organ failure following severe trauma? - A post mortem examination. Circulatory Shock 1991; 34(1): 42.
8. Krettek C, Schandelmaier P, Pape HC, Tscherne H. Moderne Osteosyntheseverfahren zur verbesserten Schonung der Fragmentdurch-blutung: Marknagelung. Langenbecks Arch. Chir., Suppl.: 1991; 882-892.
9. Pape HC, Regel G, Dwenger A, Sturm JA. Lungenfunktion nach Oberschenkelmarknagelung im Staub‘schen Schafmodell - Einfluss durch häm. Schock und Lungenkontusion? Hefte zu "Unfallheilkunde" 1992; 220: 506-508.
10. Pape HC, Regel G, Dwenger A, Sturm JA. Early intramedullary nailing of long bone fractures-Risk for the Multiple Trauma Patient? J Orthopaedic Trauma 1992; 6(4): 489.
55 Curriculum Vitae, HC Pape MD, FACS
11. Pape HC, Regel G, Borgmann W, Sturm JA. Continuous kinetic positioning in posttraumatic ARDS - A useful therapeutic alternative? European Surgical Research 1992; 24(2): 25.
12. Pape HC, Auf'm'Kolck M, Paffrath T, Regel G, Sturm JA, Tscherne HJ. Primary intramedullary stabilization of femoral shaft fractures in polytraumatized patients with associated pulmonary injury - Increased risk of ARDS? J Trauma 1992; 33(1):159.
13. Pape HC, Auf’m’kolck M, Paffrath T, Regel G, Sturm JA, Tscherne H. Gut permeability disturbances in polytraumatized patients - Is there a relationship to multiple organ failure? Circulatory Shock 1992; 37(1): 56.
14. Pape HC, Dwenger A, Grotz M, Regel G, Tscherne H. Influence of reamed vs unreamed intramedullary femoral nailing on lung function in multiple trauma patients. J Trauma 1993; 34(1):175.
15. Pape HC, Dwenger A, Kotzerke J, Znidar S, Regel G. Capacity of reticuloendothelial system function and of circulating neutrophils in multiple trauma patients. Circulatory Shock 1993; 40(1).
16. Pape HC, Regel G, Grotz M, Tscherne H. Continuous axial rotation - A supportive treatment alternative in posttraumatic ARDS. Am.Rev. Resp. Dis. 1993; 4.
17. Pape HC, Kotzerke J, Dwenger A, Grotz M, Lang H, Regel G. Changes of reticuloendothelial system function and of circulating neutrophils in multiple trauma patients. European Surgery Research 1993; 25(1): 68.
18. Pape HC, Dwenger A, Kotzerke J, Znidar S, Abel M, Regel G. Leberfunktionsstörung, stationäres (RES) und zirkulierendes Immunsystem bei schwerem Trauma - Bezug zum multiplen Organversagen. Intensivmedizin und Notfallmedizin 1993; 30(7): 395.
19. Pape HC, Dwenger A, Regel G, Remmers D, Sturm JA. Oberschenkelmarknagelung führt im Experiment bei zusätzlichem Trauma zur Lungenschädigung - Ist dies durch alternative Nagelverfahren zu vermeiden? Hefte zu "Der Unfallchirurg" 1993; 230: 1050-1052.
20. Pape HC, Regel G, Dwenger A, Tscherne H. Beeinflusst der Operationszeitpunkt der Sekundaeroperation die Prognose des polytraumatisierten Patienten? Hefte zu "Der Unfallchirurg" 1993; 232: 86.
21. Pape HC, Regel G, Auf'm'kolck M, Tscherne H. Primäre Oberschenkelmarknagelung bei Polytrauma mit Lungenkontusion - Erhöhtes ARDS-Risiko? Langenbeck's Arch. Chir. Suppl.: 1993; 931-934.
56 Curriculum Vitae, HC Pape MD, FACS
22. Pape HC, Dwenger A, Grotz M, Remmers D, Regel G, Tscherne H. Der Einfluß verschiedener Aufbohrverfahren zur Oberschenkelmarknagelung auf pulmonale Komplikationen im Tierexperiment. Chir. Forum f. klin. und exp. Forschung: 1994; 495-498.
23. Pape HC, Regel G, Sturm JA., Tscherne H. Hat der Schweregrad des Bauchtraumas einen Einfluß auf das posttraumatische Multiorganversagen? Hefte zu "Der Unfallchirurg" 1994; 239: 6-9.
24. Pape HC, Dwenger A, Grotz M, Schweitzer G. Reduktion pulmonaler Komplikationen nach Femurmarknagelung bei schwerem Trauma durch alternative Aufbohrverfahren - Ein tierexperimentelles Modell. Hefte zu "Der Unfallchirurg" 1994; 241: 333-335.
25. Pape HC. Postprimäre Frakturversorgung innerhalb der ersten 24 Std. von Wirbelsäulen-verletzungen, Thoraxwandinstabilität, stammnahen Schaftfrakturen und komplexen Handverletzungen. Hefte zu "Der Unfallchirurg" 1994; 241: 570- 572.
26. Pape HC, Dwenger A, Remmers D, Regel G, Tscherne H. Unreamed femoral nailing prevents lung function impairment and increased inflammatory response in polytrauma. Intensive Care Medicine 1994; 20(1): 91.
27. Pape HC, Grotz M, Dwenger A, Regel G, Tscherne H. Increased gut permeability correlates with the inflammatory response in multiple trauma patients. Intensive Care Medicine 1994; 20(1): 18.
28. Pape HC, Regel G, Remmers D, Sturm JA, Tscherne H. Timing secondary surgery after multiple trauma - Influence on the development of posttraumatic multiple organ failure. Intensive Care Medicine 1994; 20(2): 86.
29. Pape HC, Grotz M, Dwenger A, Sturm JA, Tscherne H. Influence of reamer type on lung function after intramed: Nailing in sheep. J Trauma 1994; 36(1): 155.
30. Stalp M, Pape HC, Regel G. Dokumention, Qualitätssicherung, Forschung und Patientenversorgung - ein Widerspruch? Ein computergestütztes Erfassungssystem für Unfallpatienten Intensivmedizin und Notfallmedizin 1997; 34(1).
31. Pape HC, Bader A, Stalp M, Regel G. Effects of endotoxin in a newly developed 3- d hepatocyte / hepatic sinusoidal cell coculture – modulation by kupfer cell addition? Shock, Supp., 1997; 7:235.
32. Pape HC, Remmers D, Regel G, Tscherne H. Evaluation thorakaler Verletzungsschwere und ihre Bedeutung für den posttraumatischen Verlauf - eine retrospektive Untersuchung an 1326 Patienten. Langenbeck`s Arch Chir., Suppl. II: 1997; 1270-1273,.
57 Curriculum Vitae, HC Pape MD, FACS
33. Remmers D, Pape HC, Baur H, Regel G. Initialbeurteilung des Thoraxverletzungsschweregrades – Retrospektive Evaluierung an 1326 Patienten Hefte zu "Der Unfallchirurg": 1997; 322-323.
34. Pape HC, Lehmann U, Grotz M, Regel G. Heterotopic ossificaton in polytrauma patients with or without head trauma - Different pathogenetic mechanisms? Shock, Suppl, 1997; 8(2).
35. Pape HC, Lehmann U, Grotz M, Regel G. Kupfer cells augment et-effects in a new 3-d Hepatocyte / sinusoidal cell coculture. Shock, Suppl, 1997; 8(33).
36. Pape HC, Lehmann U, Grotz M, Regel G. Death in patients with blunt thoracic trauma: What are the high-risk injuries? Shock, Suppl. 1997; 8(42).
37. Pape HC, Regel G. H.Baur und AG "Polytrauma” Einfluß der Sekundäroperation auf den klinischen Verlauf - eine Untersuchung an 1037 Patienten des DGU Traumaregisters. Hefte zu "Der Unfallchirurg": 1997; 580-582.
38. Pape HC, Grotz M, Stalp M, Schedel I, Tscherne H. Organ failure after polytrauma – Related to decreased antibody release to endotoxin? Shock Suppl, 10, 1998.
39. Pape HC, Friedrich A, Krettek C, Regel G, Tscherne H. Kindliche hüftgelenksnahe Frakturen – Welche Langzeitergebnisse sind zu erwarten? Acta Chirurgica Austriaca 1998; 30(134).
40. Weinberg A, Pape HC, Blauth M, Tscherne H. Inwieweit sind posttraumatische Einschränkungen der Umwendbewegung nach Unterarmschaft-frakturen vorauszuberechnen? Hefte zu "Unfallheilkunde" 1998; 269.
41. Ziesing S, Weber S, Pape HC, Mahlke L, Tscherne H. Senkung der Antibiotikakosten durch unfallchirurgisch-mikrobiologische Zusammenarbeit. Hefte zu "Der Unfallheilkunde" 1998; 269.
42. Pape HC. Management of traumatic shock - results of the German Trauma Registry. Acta Anästhesiol. Scand., 1998; 42(112): 172-174.
43. Pape HC, Friedrich A, Krettek C, Tscherne H. Kindliche hüftgelenkshnahe Frakturen- welche Langzeitergebnisse sind zu erwarten? Acta Chirurgica Austriaca 1998; 30: 99-102.
44. Oberbeck R, Pape HC, Bastian L, Pohlemann T, Weimann A, Tscherne H. Laparotomiepflichtiges stumpfes Bauchtrauma nach Polytrauma – Eine Analyse bei 342 Patienten Hefte zu "Der Unfallheilkunde" 1998, 269.
45. Remmers D, Pape HC, Baur H, Tscherne H. Isoliertes Thoraxtrauma versus Thoraxtrauma bei Polytrauma – Mit welchen Komplikationen ist zu rechnen? Hefte zu "Der Unfallheilkunde 1998; 269.
58 Curriculum Vitae, HC Pape MD, FACS
46. Lehmann U, Seekamp A, Rickels E, Pape HC. Der Einfluss der Polytraumatisierung auf das Schädel-Hirn-Trauma- Eine prospektive klinische Studie. Hefte zu "Der Unfallheilkunde 1998; 269.
47. Pape HC, Baur H, Pohlemann T, Tscherne H. Beckenverletzung bei Polytrauma – Eine Untersuchung prognostischer Faktoren des DGU–Traumaregisters. Hefte zu "Der Unfallheilkunde“ 1998; 269.
48. Oberbeck JR., Hosch W, Pape HC, Jacobs R, Schedlowski M. Effects of catecholamines on expression of adhesion molecules and cell migration in man. Shock, Supp 1998; 9.
49. Stalp M, van Griensven M, Pape HC, Regel G, Tscherne H. Substitution of β- Endorphin in severe trauma-modulation of respiratory burst of PMNL Shock, Supp 1998; 9.
50. Pape HC, Grotz M, Stalp M, Schedel I, Tscherne H. Decreased antibody release to endotoxin, infections and late organ failure after polytrauma. Shock, Supp 1998; 9.
51. Pape HC, van Griensven M, Schmidt RE, Tscherne H. Timing of major surgery and cytokine release after trauma: Prediction of post-OP complications? Shock, Supp 1999; 11.
52. Lehmann U, Pape HC, Winny M, Zech S, Rickels E, Lorenz M. The consequences of multiple trauma and injury pattern on severely head injured patients. Shock, Supp 1999; 11.
53. Oberbeck JR, Dahlweid FM, Koch R, Pape HC, Tscherne H. Dehydroepiandrosterone improves survival rate and immune function after polymicrobial sepsis. Shock, Supp 1999; 11.
54. Lehmann U, Winny M, Zech S, Molitoris U, Rickels E, Lorenz M, Regel G, Pape HC, Seekamp A. Schädel-Hirn-Trauma und Polytrauma mit Schädel-Hirn- Trauma- Prädiktoren zur frühzeitigen Beurteilung des Outcomes. Acta Chir. Austriaca 1999; 31(156): 144-146.
55. Lehmann U, Gobiet W, Steinbeck K, Regel G, Seekamp A, Pape HC. Spätergebnisse polytraumatisierter Patienten mit schwerem Schädel-Hirn-Trauma Acta Chir. Austriaca 1999; 31(156): 153-156.
56. Pohlemann T, Gänsslen A, Pape HC, Hüfner T, Tscherne H. Analyse und Korrektur posttraumatischer Beckenringdeformitäten. Deutsche Gesellschaft für Unfallchirurgie, Kongressband, 1999.
57. Pape HC, Remmers D, Stalp M, Tscherne H. Levels of antibodies to endotoxin and cytokine release in patients with severe trauma – Does posttraumatic dysergy contribute to organ failure? Intensive Care Medicine 1999; 25(1).
59 Curriculum Vitae, HC Pape MD, FACS
58. Stalp M, Pape HC, Koch C, Tscherne H. Outcome after severe trauma-development of a new rehabilitation score for poly-traumatised patients. Intensive Care Medicine 1999; 25(1).
59. Pape HC, Nickel E, Dahlweid F, Oberbeck R, Tscherne H, Regel G. Das Zusammenspiel des stationären und mobilen Immunsystems im Rahmen des septiformen Traumaverlaufes. Journal für Anästhesie und Intensivbehandlung 1999; 117-122.
60. Tscherne H, Pape HC. 30 Jahre Polytrauma – Ein Erfahrungsbericht Deutsche Gesellschaft für Unfallchirurgie, Kongressband, 2000.
61. Pape HC, Hildebrandt F, Stalp M, Ebisch M, Krettek C. Entwicklung eines neuen, CT-unabhängigen Scoresystems (TTS) zur Beurteilung der Thoraxverletzungsschwere. Deutsche Gesellschaft f. Unfallchirurgie Kongressband. 2001; 589.
62. Stalp M, Winny M, van Griensven M, Pape HC. Major secondary surgery in blunt trauma patients and perioperative cytokine liberation: Determination of the clinical relevance of biochemical markers. American Association for the Surgery of Trauma 2000; 49(2):382.
63. Richter M, Krettek C, Otte D, Stalp M, Ernst S, Pape HC. Crash severity, injury severity and the clinical course in car occupants with thoracic trauma - A technical and clinical prospective investigation. American Association for the Surgery of Trauma (Abstracts) 2000.
64. Pape HC, Stalp M, Pirente N, Neugebauer E, Tscherne H. Objective and subjective outcome 2 years after polytrauma: An investigation by the German Trauma Registry. J Orthopaedic Trauma 2000;14(2): 126.
65. Panzika M, Pape HC, Stalp M, Krettek C. Changes in the management of femoral shaft fractures in polytrauma – from early total care to damage control orthopaedic surgery. American Association for the Surgery of Trauma J. Trauma 2001; 51 (1):202.
66. Hildebrand F, van Griensven M, Seekamp A, Pape HC. Welche Bedeutung haben systemische Zytokinspiegel bei Schädel-Hirn-Trauma mit und ohne Begleitverletzungen. Hefte zu "Der Unfallchirurg" 2001; 225.
67. Panzika M, Pape HC, van Griensven M, Brabant G, Krettek C. Hat der Schweregrad des Schädelhirntraumas einen Einfluß auf die systemische Freisetzung von mineralisationsspezifischen Hormonen des Knochenstoffwechsels? Hefte zu "Der Unfallchirurg" 2001; 226-227.
60 Curriculum Vitae, HC Pape MD, FACS
68. Grimme K, Pape HC, Panzika M, Krettek C. Klinische Auswirkungen der Änderung der Behandlungsstrategie von Oberschenkel-schaftfrakturen bei Polytrauma – eine retrospektive Analyse. Hefte zu "Der Unfallchirurg" 2001; 401- 402.
69. Pape HC, Grimme K, van Griensven M, Wiese B, Zelle B, Krettek C. Impact of 1° intramedullary instrumentation versus damage control for femoral fractures in polytrauma: A prospective randomized analysis American Association for the Surgery of Trauma J. Trauma 2002; 53(1):184.
70. Panzika M, Zelle B, Stalp M, Pape HC, Krettek C. Objektive und subjektive Langzeitergebnisse nach Polytrauma – eine Untersuchung von 499 Patieten. Hefte zu "Der Unfallchirurg" 2002; 99-100.
71. Pape HC, Zelle B, Sittaro N, Krettek C. Krankheitsaufkommen, -auswirkungen und ökonomische Aspekte: Ein fächerübergreifender Vergleich Hefte zu "Der Unfallchirurg" 2002; 407-408.
72. van Griensven M, Hoevel P, Hildebrand ., Grotz M, Pape HC. The importance of IL-6 in the pathogenesis of polymicrobiol sepsis and DHEA treatment. Shock, Supp 2002; 17: 20.
73. Hildebrand F, van Griensven M, Mahlke L, Krettek C, Pape HC. L-Selectin shows time and gender dependency in association with MODS. Shock, Supp 2002; 17: 25.
74. Mahlke L, van Griensven M, Stalp M, Pape HC. NK-cells and the late hypersensitivity reaction, but not T-lymphocyte apoptosis is involved in the beneficial effects of DHEA in a two-hit rodent model. Shock, Supp 2002; 17: 33.
75. Wittwer T, Pape HC, Kuzu M, Tschernig T, van Griensven M. Polymicrobiol sepsis enhanced granulocyte adhesion to lung endothelium in a murine two hit model of trauma. Shock, Supp 2002; 17: 65.
76. Hildebrand F, Stuhrmann M, van Griensven M, Hasenkamp S, Krettek C, Pape HC. Genetic predisposition for a compromised immune system after severe trauma. American Association for the Surgery of Trauma J. Trauma 2003; 553(1):206.
77. Barkhausen T, Pape HC, Breddin M, Böttcher F, van Griensven M. DHEA differentially modulates cytokine expression on transcriptional and translational level in a multiple hit model of trauma. Shock, Supp 2003; 19: 21.
78. van Griensven M, Barkhausen T, Baumann M, Pütz C, Krettek C, Pape HC. DHEA modulates cytokine RNA expression on a transcriptional level independent of TNF-R1. Shock, Supp 2003; 19:24.
79. Hildebrand F, Pape HC, Krettek C, van Griensven M. Role of adhesion molecule ICAM-1 in the pathogenesis of polymicrobial sepsis and DHEA-treatment. Shock, Supp 2003; 19: 63.
61 Curriculum Vitae, HC Pape MD, FACS
Other Publications
1. Pape HC. Letter to the editor: Pulmonary and systemic fat embolization after medullary canal pressurization. J Trauma 1999; 47(1): 190.
2. Giannoudis PV, Pape HC. Letter to the editor. J Trauma 2002; 52(4): 811.
3. Pape HC. Invited commentary. J Orthop Trauma. 2007 Aug;21(7):481-3.
PROFESSIONAL ACTIVITIES
Scientific Presentations 1. Pape HC Regel G Nerlich ML Sturm JA Tscherne H Pulmonale Komplikationen bei Polytrauma mit Oberschenkelschaftfrakturen – Einfluß durch Operationsverfahren ? Zentraleuropäischer Anästhesiekongress (ZAK) , Innsbruck, 12.-16.9.1989
2. Pape HC Regel G Sturm JA Tscherne H Ist das akute Nierenversagen nach Polytrauma therapeutisch zu beeinflussen ? 53. Jahrestagung der Deutschen Gesellschaft für Unfallchirurgie, 22.-25.11.1989, Berlin
3. Pape HC Regel G Dwenger A Sturm JA Does additional lung injury and hem. shock aggravate lung damage from intramedullary femoral nailing in sheep? Thirteenth annual conference on shock, Durango, Colorado June 8-11, 1990
4. Pape HC Jonas M Dwenger A Schweitzer G Regel G Sturm JA Influence of intramedullary femoral nailing on pulmonary capillary permeability, hemodynamics and cell functions after pulmonary injury in sheep European Society for Surgical Research, May 6-9, 1990 Berlin
5. Pape HC Regel G Sturm JA Hat der Schweregrad des Bauchtraumas einen Einfluß auf das posttraumatische Multiorganversagen? 26. Jahrestagung, Österreichische Gesellschaft für Unfall-chirurgie 4.-6.10. 1990 Salzburg
6. Pape HC Versorgung des polytraumatisierten Patienten auf der Intensivstation Fortbildungsveranstaltung fÜr Intensivpflegepersonal, 7.11.1991, Med. Hochschule Hannover
7. Pape HC Regel G Dwenger A Sturm JA Lungenfunktion nach OS-Marknagelung im Staub Schen Schafmodell 54. Jahrestagung der Deutschen Gesellschaft für Unfallheilkunde 28.Nov.-1.Dez. 1990 Berlin
8. Pape HC
62 Curriculum Vitae, HC Pape MD, FACS
Langzeitergebnisse nach Polytrauma 90. Unfallseminar Unfallchirurgische Klinik, Medizinische Hochschule Hannover Thema: "Der Scherverletzte", 16.2.1991 Hannover
9. Pape HC Regel G Sturm JA Tscherne H Is there a pattern of organ failure following severe trauma – a post mortem study 2nd International Congress on the "Immune Consequences of Trauma shock and Sepsis March 6-9, 1991, Munich
10. Pape HC Dwenger A Regel G Remmers D Sturm, JA Lung damage and granulocyte stimulation following intramedullary femoral nailing can be reduced by unreamed procedures in severely injured sheep European Society for surgical Research, 26. Congress, May 8-11, 1991 Salzburg
11. Pape HC Dwenger A Regel G Sturm JA OSMN führt im Experiment bei zusätzlichem Trauma zur Lungenschädigung? 6. Deutsch-Österreichisch-Schweizerische Unfalltagung , 21.-25.5.1991 Wien 12. Pape HC Regel G SturmJA Tscherne H Is there a pattern of organ failure following severe trauma? 2nd "International conference on Shock", June 2-5, 1991 Wien
13. Pape HC Pathogenese und Klinik des multiplen Organversagens nach schwerem Trauma Fortbildungsveranstaltung für Intensivpflegepersonal, 10.8.1991, Med. Hochschule Hannover
14. Pape HC Effects of intramedullary nailing on pulmonary function in animal and clinical studies Regionale Refereeravend, University of Nijmegen, Department of Surgery 12.9.1991 Nijmegen, Netherlands
15. Pape HC Clinical and morphological changes in patients dying after severe trauma - an autopsy study. University of Nijmegen, Netherlands St.Radboud Hospital, Department of Surgery 13.9.1991, Nijmegen
16. Pape HC Dwenger A Regel G Sturm JA Tscherne H Pulmonary failure after intramedullary femoral nailing in polytrauma - is there an effect of the nonspecific immune system? 5th International Symposium "Endocrinology in Anesthesia and critical care medicine.” 25.-26. 10.1991, Berlin
17. Pape HC Regel G Sturm JA Tscherne H Lungenfunktion nach Oberschenkelmarknagelung im Experiment - hat die allgemeine Verletzungsschwere einen Einfluß? AO-Symposium, Mainz, Johannes-Gutenberg Universität, 7.-8.2.1992.
18. Pape HC Dwenger A Gollub F Sturm JA Intestinal failure and multiple organ failure after Polytrauma Fifth annual meeting of the "Surgical Infection Society of North America", April 9-11, 1992, Los Angeles
19. Pape HC Regel G BorgmannW Sturm JA Continuous kinetic positioning in posttraumatic ARDS – a useful clinical tool?
63 Curriculum Vitae, HC Pape MD, FACS
Twenty-seventh Congress of the "Ëuropean Society for Surgical Research", May 20-23 1992, Zaragoza, Spain
20. Pape HC Dwenger A Gollub F Sturm JA Gut permeability in polytraumatized patients – is there a relationship to MOF "Fifteenth Annual Conference on Shock" June 7-10 1992, Point Clear, Alabama
21. Pape HC Regel G Borgmann W Sturm JA Tscherne H ARDS following severe trauma – does kinetic positioning represent a crucial treatment alternative? Fifth International meeting of the "International Trauma Anesthesia and Critical Care Society" June 11-12 1992, Amsterdam
22. Pape HC Auf‘m‘Kolck M Paffrath T Regel G Sturm JA Tscherne H Primary intramedullary stabilizatipon of femoral shaft fractures in patients with associated pulmonary unjury – increased risk of ARDS? Fifty Second Annual meeting of the "American Association for the Surgery of Trauma" September 17-19, 1992, Louisville, Kentucky 23. Pape HC Dwenger A Gollub F Tscherne H Störungen der Darmpermeabilität nach schwerem Trauma – eine klninsche Studie "Deutscher Anaesthesiekongress 1992", 26.-30.9.1992, Berlin
24. Pape HC Pulmonale Komplikationen nach primärer OS-Marknagelung in der Klinik Fortbildungsveranstaltung, Klinik für Anaesthesie I, Med. Hochschule Hannover, 19.10.1992, Hannover
25. Pape HC Regel G Dwenger A Tscherne H Beeinflusst der Zeitpunkt der Sekundäroperation die Prognose des polytraumatisierten Patienten? 56. Jahrestagung der "Deutschen Gesellschaft für Unfallchirurgie" 18.-21.11. 1992, Berlin 26. Pape HC Regel G Dwenger A Tscherne H. Auswirkungen verschiedener Verfahren der OS-Marknagelung auf die Lungenfunktion nach schwerem Trauma "Osteosynthese International" 30.11. 1992, Frankfurt
27. Pape HC Histopathology after severe trauma International Congress on "The Integrated Approach to Trauma Care" December 3-5, 1992, Leuven, Belgium
28. Pape HC Möglichkeiten der Überwachung der Volumentherapie mittels Swan Ganz – Katheter Fortbildungsveranstalung Unfallchirurgie und Anåsthesie, Klinik Salzdahmlemmerstr. 2.2.1993, Braunschweig
29. Pape HC Versorgung schwerverletzter Patienten auf der Intensivstation unter Berücksichtigung posttraumatischer Komplikationen Fortbildungsveranstaltung für Facharztausbildung, 3.2.1993, Augsburg 30. Pape HC Regel G Sturm JA Tscherne H Intramedullary femoral nailing in polytraumatized patients with lung contusion - increased risk of ARDS, if performed primarily?
64 Curriculum Vitae, HC Pape MD, FACS
American Association of Orthopedic Surgeons, San Francisco, CA, February 18/23, 1993 31. Pape HC Dwenger A Grotz M Regel G Tscherne H Influence of reamed versus unreamed intramedullary nailing on lung function in polytrauma patients Western Trauma Association Snowbird, Utah Feb. 27/march 6, 1993 32. Pape HC Regel G Grotz M Tscherne H Primäre Oberschenkelmarknagelung bei Polytrauma mit Lungenkontusion - erhöhtes Ards Risiko? 110. Jahrestagung Deutsche Gesellschaft für Chirurgie 17.4.1993, München. 33. Pape HC Effekte der kinetischen Therapie bei Schwerverletzten mit ARDS. 1.Symposium für kinetische Therapie, Klinikum Großhadern, 29.4.1993
34. Pape HC Dwenger A Kotzerke J Znidar S Regel G Capacity of reticuloendothelial system function and of circulating neutrophils in multiple trauma patients Wiener Schockgespräche, März 9-13, 1993 Wien 35. Pape HC Regel G Complications after intramedullary famoral nailing in animal models and in humans Fortbildungsveranstaltung AO-Forschungsinstitut, 14.3.1993, Davos
36. Pape HC Grotz M Zeichen J Dwenger A Regel G Gut permeability in trauma patients - is there a relationship to multiple organ failure? 28th Congress of the European Society for Surgical Research, 23.-26.5.1993, Turku, Finland
37. Pape HC Kotzerke J Dwenger A Grotz M Lang H Znidar S Regel G Changes of reticuloendothelial function and of circulating neutrophils in multiple trauma patients 28th Congress of the European Society for Surgical Research, 23.-26.5.1993, Turku, Finland 38. Pape HC Regel G Grotz M Tscherne H Primäre OS-Marknagelung bei Polytrauma mit Lungenkontusion – erhöhtes ARDS-Risiko? 34. Jahrestagung Österreichische Gesellschaft für Unfallchirurgie, Innsbruck 10.-12.6.1993 39. Pape HC Regel G Lobenhoffer P Grotz M Lehmann U Tscherne H Vergleich der Behandlungsergebnissse schwerverletzter 1972-80 und 1982-1991 34. Jahrestagung Österreichische Gesellschaft für Unfallchirurgie, Innsbruck 10.-12.6.1993
40. Pape HC Dwenger A Grotz M Regel G Tscherne H Prevention of pulmonary dysfunction from intramedulklary femoral nailing by different nailing techniques in a sheep model of severe trauma Orthopedic Trauma Association 25.9.1993, New Orleans
41. Pape HC Zwipp H Hoffmann M Regel G Tscherne H Intramedullary reaming in patients with refractory osteomyelitis of long bones European Congress of bone and joint infections. 7.-9.10.1993, Munich
42. Pape HC Möglichkeiten und indikationen des swan-ganz Katheters Fortbildungsveranstaltung für Intensivpflegepersonal, 14.10.1993, Med. Hochschule Hannover
65 Curriculum Vitae, HC Pape MD, FACS
43. Pape HC Regel G Sturm JA Kinetic therapy in the treatment and prevention of ARDS 2nd International meeting on kinetic therapy 19.-25.10.1993, San Antonio Texas.
44. Pape HC Neue Therapiekonzepte beim ARDS II.Grenzlandsymposium, "Der Polytraumatisierte Patient". Marktredwitz 29.-30.10. 1993
45. Pape HC Dwenger A Grotz M Schweitzer G Reduktion pulmonaler Komplikationen nach OS-Nagelung bei schwerrem Trauma durch alternatiove Aufbohrverfahren 57. Jahrestagung Deutsche Gesellschaft für Chirurgie, 17.-20.11.1993, Berlin 46. Pape HC Postprimäre Frühversorgung innerhalb der ersten 24 Std. 57. Jahrestagung Deutsche Gesellschaft für Chirurgie, 17.-20.11.1993, Berlin
47. Pape HC Dwenger A Kotzerke J Znidar S Abel M Regel G Leberfunktionsstörung, stationäres und zirkulierendes Immunsystem bei schwerem Trauma – Bezug zum MOF ? 2, Deutscher Interdisziplinärer Kongress für Intensivmedizin , 24.-27.11.1993, Hamburg 48. Pape HC Akutes Lungenversagen – kinetische Therapie Ernst v. Bergmann Akademie f. Ärztl. Fortbildung, Ärztekammer Berlin, 6.1.1994
49. Pape HC Das Thoraxtrauma 5. Seminar f. Ärzte im Rettungsdienst der Arbeitsgemeinschaft d.Notärzte Niedersachsens, Städt. Kliniken Osnabrück, 15.1.1994
50. Pape HC Regel G Sturm JA Tscherne H Unreamed femoral nailing reduces pulmonary dysfunction of intramedullary instrumentation in severely traumatized sheep International Symposium "Minimal invasive Traumatology", Salzburg, 3.-4.2.1994 51. Pape HC Regel G Grotz M Dwenger A Tscherne H Pulmonary dysfunction after reamed intramedullary femoral nailing in sheep – influence of different nailing methods AAOS 61st Annual meeting New Orleans, February 24-28, 1994 52. Pape HC Regel G Grotz M Dwenger A Sturm JA Tscherne H Influence of reamer type on lung function after intramedullary reamed nailing in sheep WTA 24th Annual meeting, Crested Butte, Colorado, 27.2.-4.3.1994
53. Pape HC Regel G Grotz M Dwenger A Sturm JA Increased gut permeability correlates with the inflammatory response in multiple trauma patients Immune Consequences of Trauma Shock and Sepsis, München
54. Pape HC Grotz M Regel G Dwenger A Tscherne H Der Einfluss verschiedener Aufbohrverfahren auf die Lungenfunktion im Tierexperiment Chirurgisches Forum, 111. Tagung der Deutschen Gesellschaft für Chirurgie, München, 5.-9.4. 1994
66 Curriculum Vitae, HC Pape MD, FACS
55. Pape HC Intensivmedizinische Prinzipien der Polytraumaversorgung unter besonderer Berücksichtigung des posttraumatischen Organversagens. Forbildungsveranstaltung zur Facharztausbildung des BDC Augsburg, 21. Januar 1995
56. Pape HC Kinetische Lagerung und Lungenfunktion beim posttraumatischen Lungenversagen 5. Internationales Intensivmedizinisches Symposium Bremen, 16.-18. Februar 1995
57. Pape HC Die Bedeutung der Kinetischen Therapie bei posttraumatischem Lungenversagen Symposium "Kinetische Therapie" Regensburg , 11. Februar 1995
58. Pape HC Die Bedeutung des schweren Thoraxtraumas Fortbildungsveranstaltung der AGNN Osnabrück, 16.-19. März 1995
59. Pape HC Remmers D Dwenger A Regel G Tscherne H Mediatoren des granulozytären und monozytären Systems nach schwerem Trauma - ein Vergleich möglicher prädiktiver Wertigkeit bei Patienten mit MOV. 112. Tagung der Deutschen Gesellschaft für Chirurgie Berlin, 18.-22. April 1995
60. Pape HC Dwenger A Remmers D Regel G Patterns of intestinal permeability changes and inflamatory response in polytrauma patients. Fifth Vienna Shock Forum Wien, 7.-11. Mai 1995
61. Pape HC Pulmonary and inflamm. changes after reamed intramedullary nailing in sheep. International Symposium on "The science of intramedullary reaming" Hong Kong, 23.-24. September 1995
62. Pape HC Systemic effects of reamed and unreamed femoral nailing in polytrauma patients. International Symposium on "The science of intramedullary reaming" Hong Kong, 23.-24. September 1995
63. Pape HC Operationstrauma des ungebohrten Oberschenkelmarknagels aus experimenteller und klinischer Sicht. Symposium - "Multiples Organversagen" München, 9.-11. November 1995
64. Pape HC Remmers D Regel G Tscherne H Einfluß der Sekundäroperation auf posttraumatische MOV-Inzidenz bei Polytrauma? Deutscher Interdisziplinärer Kongress für Intensivmedizin Hamburg, 6.-9. Dezember 1995
65. Pape HC Prinzipien der Versorgung schwerverletzter Patienten im Wandel der Zeit. Antrittsvorlesung, Medizinische Hochschule Hannover, Hannover, 20. Januar 1996
66. Pape HC Problematik der Oberschenkelmarknagelung bei Polytrauma mit begleitendem Thoraxtrauma. Forbildungsveranstaltung, Der Unfallchirurgische Klinik Bergmannsheil Bochum, 20. Februar 1996
67 Curriculum Vitae, HC Pape MD, FACS
67. Pape HC Aktueller Stand der Behandlung polytraumatisierter Patienten. Fortbildungsveranstaltung Diakoniekrankenhaus Alten Eichen Hamburg, 24. April 1996
68. Pape HC Kinetische Therapie beim posttraumatischen Lungenversagen: Indikationen – Management Symposium: Beatmungsstrategien mit kinetischer Therapie Wuppertal, 11. Mai 1996
69. Pape HC Bader A Regel G Tscherne H Leberversagen im MOV - initiiert durch zelluläre Toxizität von Endotoxin? Zentraleuropäischer Unfallkongres Davos, 29. Mai -1. Juni 1996
70. Pape HC Remmers D Grotz M Regel G Tscherne H Posttraumatisches multiples Organversagen im chronischen Schafmodell - Reduktion des Organschadens durch Therapie mit Lazaroid U-74389 G? 60. Jahrestagung der Deutschen Gesellschaft für Unfallchirurgie Berlin, 20.-23. November 1996
71. Pape HC Remmers D Regel G Tscherne H Was ist ein schweres Thoraxtrauma? 158. Tagung der Vereinigung Nordwestdeutscher Chirurgen Hamburg, 5.-7. Dezember 1996
72. Pape HC Die intensivmedizinische Behandlung des schwerverletzten Patienten. Seminar BDC Augsburg, 18. Januar 1997
73. Pape HC Systemic consequences of femoral nailing. AO nailing seminar Limassol (Zypern), 1.-2. Februar 1997
74. Pape HC Instruments and implants for unreamed femoral nailing AO nailing seminar Limassol (Zypern), 1.-2. Februar 1997
75. Pape HC Special technique of unreamed femoral nailing. AO nailing seminar Limassol (Zypern), 1.-2. Februar 1997Pape HC Das schwere Thoraxtrauma - Entscheidungshilfen bei der Diagnostik und Therapie. 7. Internationales intensivmedizinisches Symposium. "Rationale Konzepte der intensivmedizinischen Praxis". Bremen, 21.-22. Februar 1997
76. Pape HC Effects of endotoxin in a newly developed 3-D hepatic sinusoidal cell coculture model. 4th International congress on the "Immune consequences of trauma, shock and sepsis". München, 4.-8. März 1997
77. Pape HC Remmers D Regel G Tscherne H Evaluation thorakaler Verletzungsschwere und ihre Bedeutung für den posttraumatischen Verlauf - eine retrospektive Untersuchung an 1326 Patienten. 114. Tagung der deutschen Gesellschaft für Chirurgie München, 1.-4. April 1997
78. Pape HC Pathophysiologie des traumatisch-hämorrhagischen Schocks. Fortbildung Sanitätsoffizierszentrum, Emmich Cambrai Kaserne Hannover, 30. April 1997
68 Curriculum Vitae, HC Pape MD, FACS
79. Pape HC Einfluß der Frakturstabilisierung auf den Verlauf des Schädel-Hirn-Traumas. Traumakurs Ost, "Das Polytrauma" Magdeburg, 27.-28. Juni 1997
80. Pape HC Friedrich A Krettek C Regel G Tscherne H Kindliche Hüftgelenksnahe Frakturen - welche Langzeitergebnisse sind zu erwarten? Jahrestagung der Österreichischen Gesellschaft für Unfallchirurgie Salzburg, 2.-4. Oktober 1997
81. Pape HC Kinetische Therapie beim Polytrauma. Symposium "Beatmungstherapie und kinetische Behandlungskonzepte in der operativen Intensivmedizin: Standortbestimmung, Kontroversen und Perspektiven. Unfallchirurgische Klinik (Prof. Dr.Gotzen) , Philipps-Universität Marburg, Marburg, 8. November 1997
82. Pape HC Regel G Stalp M Baur H AG Polytrauma der DGU. Einfluß der Sekundäroperation auf den klinischen Verlauf - eine Untersuchung an 1037 Patienten des DGU Traumaregisters. Deutsche Gesellschaft für Unfallchirurgie Berlin, 21.-22. November 1997
83. Pape HC Remmers D Baur H Regel G Initialbeurteilung des Thoraxverletzungsschweregrades - retrospektive Evaluierung bei Polytraumatisierten. Deutsche Gesellschaft für Unfallchirurgie Berlin, 21.-22. November 1997
84. Pape HC Pathophysiology of systemic consequences of intramedullary nailing. International Symposium on femoral nailing Bern (Switzerland), 14. April 1998
85. Pape HC Preclinical treatment of polytrauma patients. Postgraduate trauma course. Malmö (Sweden), 24. April 1998
86. Pape HC Grotz M Bastian L Gänsslen A Pohlemann T Tscherne H Blunt abdominal trauma in 342 patients requiring laparotomy - epidemiology, mortality and relevant factors for treatment algorithms. 3rd European Congress for Traumatology Amsterdam, 17.-20. Juni 1998
87. Pape HC Krettek C Baur H Tscherne H Fractures of the femoral head and neck in children - a long term follow-up study. American Association for the Surgery of Trauma Baltimore, 24.-26. September 1998
88. Pape HC Management of traumatic shock 3rd Vienna Congress on Anesthesiology and Intensive Care Medicine Wien, 29. September –3. Oktober 1998
89. Pape HC Organ failure after polytrauma - related to decreased antibody release to endotoxin 8 th Congress of the European Shock Society La Hulpe (Belgium), 15.-17. Oktober 1998
69 Curriculum Vitae, HC Pape MD, FACS
90. Pape HC Organisation des Traumaregisters der DGU. Workshop der "Arbeitsgemeinschaft Polytrauma" Essen, 24. Oktober 1998
91. Pape HC Tscherne H. Der Schwerverletzte mit multiplen Frakturen: Das klinische Management. Symposium: 25 Jahre Unfall- und Handchirurgie, Unfallchirurgische Klinik, Westfälische Wilhelms- Universität Münster Münster, 4. Septmber 1998
92. Pape HC Baur H Pohlemann T Gänsslen A Tscherne H Beckenverletzungen beim Polytrauma - eine Untersuchung prognostischer Faktoren anhand des DGU-Traumaregisters. 62. Jahrestagung der Deutschen Gesellschaft für Unfallchirurgie e.V. Berlin, 18.-21. November 1998
93. Pape HC Respiratory problems after femoral osteosnthesis in polytrauma. Assoziatione Laziale Ortopedici Traumatologi Ospedalieri, XXXIII Congresso "La Traumatologia della strada, oggi" Rom, 11. Dezember 1998
94. Pape HC Intramedullary nailing: To ream or not to ream. Advances in fracture managament - advanced course Davos, 14. Dezember 1998
95. Pape HC Antero- or retrograde nail insertion in the femur? Advances in fracture managament - advanced course Davos, 14. Dezember 1998
96. Pape HC Physiologische Wirkung kristalloider Lösungen in der Volumenersatztherapie 9. Internationales Symposium Intensivmedizin & Intensivpflege Bremen, 10.-12. Februar 1999
97. Pape HC Polytrauma mit Beckenfraktur in der Schwangerschaft – Therapieergebnisse von Mutter und Fötus 116. Kongreß der Deutschen Gesellschaft für Chirurgie Singen, 6.-10. April 1999Pape HC Concept of primary treatment of femoral shaft fractures 25 years of locking nailing, state of the art new perspectives Strasbourg, 5-7. Mai 1999
98. Pape HC Auswirkungen der Brustkorbverletzungen bei Polytrauma im Alter 10. Internationales Symposium Intensivmedizin Bremen, 16.-18. Februar 2000
99. Pape HC Kinetische Therapie beim Polytrauma Lagerungstherapie in der Intensivmedizin Rüsselsheim, 20. Mai 2000
100. Pape HC Verfahrenswechsel versus primäre definitive Stabilisierung (Pro Verfahrenswechsel) Notfallmedizin- Weichenstellung für die Intensivtherapie Leipzig, 15.-17. Juni 2000
101. Pape HC Kinetische Therapie in Bauch- und Rückenlage Hannover, August 2000
70 Curriculum Vitae, HC Pape MD, FACS
102. Pape HC Der Einfluß von Sekundäroperationen polytraumatisierter auf inflammatorische Parameter und postoperative Komplikationen – eine klinische Studie 64. Jahrestagung der DGU Hannover, 10.-13. September 2000
103. Pape HC Dorsoventrale Lagerung und Kinetische Therapie 167. Jahrestagung der Vereinigung Niederrhein.-Westfälischer Chirurgen Herne, 28.-30. September 2000
104. Pape HC Major Secondary Surgery in Blunt Trauma Patients and Perioperative Cytokine Liberation: Determination of the Clinical Relevance of Biochemical Markers 6th American Association for the Surgery of Trauma San Antonio, Texas, 12.-14. Oktober 2000
105. Pape HC Hypovolämischer Schock 5. Deutscher Interdisziplinärer Kongreß für Intensivmedizin und Notfallmedizin Hamburg, 22. November 2000
106. Pape HC Intramedullary nailing of the femur- Not to ream 73 rd AO Course Davos, 10.-15. Dezember 2000
107. Pape HC Kinetische Therapie und Bauchlagerung: Alternativen oder Ergänzungen? 11. Internationales Symposium Intensivmedizin / Intensivpflege Bremen, 07.-09. Februar 2001
108. Pape HC Schadensbegrenzung durch operatives Management von großen Frakturen in der Initial- und Intensivphase 11. Internationales Symposium Intensivmedizin / Intensivpflege Bremen, 07.-09. Februar 2001
109. Pape HC Lagerungsmöglichkeiten auf der Intensivstation Forum Anästhesie Luzern, 15. Februar 2001
110. Pape HC The German Trauma register: setup, first experiences and results Quality assurance and performance improvements in trauma care Utrecht, 6. April 2001
111. Pape HC Gerinnungsaktivierung bei Polytrauma 7. Heidelberger Symposium Hämostaseologie und Anaesthesie Heidelberg, 07.-08. September 2001
112. Pape HC Fracture management in Polytrauma British Trauma Society Leeds, 04.-05. Oktober 2001
113. Pape HC Nachuntersuchung 10 Jahre nach Polytrauma Jahrestreffen der europäischen Versicherungsindustrie Baden-Baden, 21. Oktober 2001
71 Curriculum Vitae, HC Pape MD, FACS
114. Pape HC Schwermann T Traumaregister und Bundesgesundheitsreport – Wie können Daten über Mehrfachverletzte rekrutiert werden? Workshop des DGU-Traumaregisters München, 26. Oktober 2001
115. Pape HC Gesundheitsberichtserstattung des Bundes in der "Bone and Joint Decade" – Epidemiologie und Gesundheitsökonomie Jahrestagung d. Deutschen Gesellschaft f. Unfallchirurgie Berlin, 15. November 2001
116. Pape HC Primäre Definitivversorgung beim Polytrauma – Nutzen oder Risiko Jahrestagung d. Deutschen Gesellschaft f. Unfallchirurgie Berlin, 15. November 2001
117. Pape HC Intramedullary nailing – to ream or not to ream 75th AO Course Davos, 09.-14. Dezember 2001
118. Pape HC Fracture management of the femur – value of damage control orthopaedics 75 th AO Course Davos, 09.-14. Dezember 2001
119. Pape HC Scoring des Thoraxtraumas I0 Thoraxtrauma-Meeting Reisenburg, 21.-22. Februar 2002
120. Pape HC Was kann/muß/darf nicht primär definitiv versorgt werden bei SHT – Thoraxtrauma – kritischer ("Borderline") Zustand? – "aus der Sicht des Unfallchirurgen" 12. Internationales Symposium Intensivmedizin Bremen, 20.-23. Februar 2002
121. Pape HC Klinische Verläufe bei schwerverletzten in Abhängigkiet des Versicherungsstatus Unfallfachausschuss, Köln, 30.4.2002
122. Pape HC Polytrauma-Scores – Sinn und Nutzen 119. Kongress der Deutschen Gesellschaft für Chirurgie Berlin, 07.-10. Mai 2002
123. Pape HC Pathophysiological Changes after Trauma The Current Principals & Controversies in Orthopaedic Trauma meeting Dublin, 15.-17. Mai 2002
124. Pape HC How can we improve the System of Care in the Third Millenium in Germany? The Current Principals & Controversies in Orthopaedic Trauma meeting Dublin, 15.-17. Mai 2002
125. Pape HC Key note lecture: Early total Care versus "Damage Control" in the polytraumatised Patient The Current Principals & Controversies in Orthopaedic Trauma meeting Dublin, 15.-17. Mai 2002
72 Curriculum Vitae, HC Pape MD, FACS
126. Pape HC Impact of I0 intramedullary instrumentation versus damage control for femoral fractures in polytrauma: a prospective randomized analysis. 61st Meeting: American Association for the Surgery of Trauma Orlando, 26.-28. September 2002
127. Pape HC Management of femoral shaft fractures in polytrauma – from early total care to damage control orthopaedic surgery. Orthopaedic Trauma Association annualmeeting Toronto, 11.-13. Oktober 2002
128. Pape HC Wie optimal ist unsere Behandlung hinsichtlich des Outcomes? 66. Jahrestagung der DGU Berlin, 13.-16. November 2002
129. Pape HC DRG und Polytrauma 66. Jahrestagung der DGU Berlin, 13.-16. November 2002
130. Pape HC Frakturstabilisierung: "Relative Stabilität: Intramedulläre Verfahren" 76th AO Course Davos, 30. November - 05. Dezember 2002
131. Pape HC Spezielle Frakturprobleme: "Polytrauma" 76th AO Course Davos, 30. November - 05. Dezember 2002
132. Pape HC Problematik der DRG – Evaluation bei Schwerverletzten 13. Symposium Intensivmedizin, Bremen 19.-21. 2. 2003
133. Pape HC Objective and Subjective outcome after Polytrauma – A Re-examination 10 years after the initial injury. American Association of Orthopaedic Surgeons, New Orleans 5.-9.2.2003
134. Pape HC Damage Control Orthopaedics: New Approaches in Orthopaedic Traumatology American Association of Orthopaedic Surgeons, New Orleans 5.-9.2.2003
135. Pape HC ”Polytrauma- Algorithmus / Scores / Outcome 120. Jahreskongress der Deutschen Gesellschaft für Chirurgie, München, 29.04.-02.05.2003
136. Pape HC Polytrauma Management 1st cooperative instructional course, Weetwood Hall, Leeds, 15-16.05.2003
137. Pape HC Damage Control Orthopaedic Surgery Orthopaedic trauma association, 19th Annual Meeting Salt LakeCity, 9.-11.10.2003
73 Curriculum Vitae, HC Pape MD, FACS
138. Pape HC Impact of Fracture Fixation on the systemic Cytokine Response in Stable Polytrauma Patients – A Prospective Randomized Analysis on Intramedullary Instrumentation versus Damage Control for Femoral Fractures Orthopaedic trauma association, 19th Annual Meeting Salt LakeCity, 9.-11.10.2003
139. Pape HC Was kostet uns ein Polytrauma – Strategien im Schatten der DRG’s Symposium: 10 Jahre Traumaregister der DGU Essen, 01.11.2003
140. Pape HC Rentabilität der Unfallchirurgie unter DRG-Bedingungen – Kosten-Nutzen Analyse für Mehrfachverletzte 67. Jahrestagung der DGU: Wissen und Visionen Berlin, 11.-14.11.2003
141. Pape HC AG Polytrauma – Wir ziehen alle Register. Entscheidungsfindung beim Polytrauma 67. Jahrestagung der DGU: Wissen und Visionen Berlin, 11.-14.11.2003
142. Pape HC Should the presence of chest trauma alter our surgical management? 78th AO Course Masters Davos, 07.-12.12.2003
143. Pape HC Debate: Are femur fractures an emergency? - pro early fixation 78th AO Course Masters Davos, 07.-12.12.2003
144. Pape HC Inflammatory cascade processes in polytrauma patients in relation to fractures care 79th AO Course Masters Davos, 14.-19.12.2003
145. Pape HC Functional outcome of the polytrauma patient: What can we accept? 79th AO Course Masters Davos, 14.-19.12.2003
146. Pape HC Hemorrhage in pelvic fracture: who needs angiography? Resident`s conference, Dept. of Orthopaedics 2.2. 2004, University of Alabama at Birmingham, USA
147. Pape HC Impact of intramedullary instrumentation versus damage control in multiple trauma Resident`s conference, Dept. of Orthopaedics 3.2. 2004, University of Alabama at Birmingham, USA
148. Pape HC Trauma Care in Germany H. Earle Conwell MD Lecture in Orthopaedic Trauma, Dept. of Surgery 4.2. 2004, University of Alabama at Birmingham, USA
149. Pape HC Effects of medullary irrigation ansd aspiration during reamed intramedullary nailing American Association of Orthopaedic Surgeons, San Francisco 10.-14.3.2004
74 Curriculum Vitae, HC Pape MD, FACS
150. Pape HC Instructional course lecture.: Damage Control Orthopaedics, Application of the DCO concept for orthopaedic injuries American Association of Orthopaedic Surgeons, San Francisco 10.-14.3.2004
151. Pape HC Instructional course lecture.: Damage Control Orthopaedics, DCO – future directions American Association of Orthopaedic Surgeons, San Francisco 10.-14.3.2004
152. Pape HC Polytrauma-massive transfusion-coagulopathy: how to avoid, how to treat World Congress of Anesthesia, 19.4.2004, Paris
153. Pape HC Infectious complications after Damage Control Orthopaedics? Orthopaedic Trauma Association, Ft. Lauderdale, FL 2004
154. Pape HC Clinical Applications of Damage Control Orthopaedics British Orthopaedic Association 35th InstructionalCourse, 14.1.2006, Birmingham UK
155. Pape HC Damage Control Orthopaedics: New Approaches in Orthopaedic Traumatology to the Isolated Extremity Injury and Polytrauma American Association of Orthopaedic Surgeons, Annual Meeting, 24.3.2006, Chicago IL
156. Pape HC Resuscitation in Pelvic Ring Disruptions 8th Annual Chicago Trauma Symposium, 28.7.2006, Chicago IL
157. Pape HC Damage Control Orthopaedics IX Current Principles and Controversies in Orthopaedic Trauma, Royal College of Surgeons, Dublin, Ireland 6.9.2006 158. Pape HC Tibial Nailing: Proximal and Distal; Lower Extemity Case Presentations Pennsylvania Orthopaedic Trauma Symposium, Pittsburgh PA, 15-16.9.2006
159. Pape HC Damage Control Orthopaedics in the Management of the Polytrauma Patient Orthopaedic Trauma Association Annual Meeting, 5.10.2006, Phoenix AZ
160. Pape HC Damage Control; Physiology of Intramedullary Nailing 2006 Annual Meeting of the Chinese Orthopaedic Association, Beijing China, 13-15.11.2006
161. Pape HC Current Concepts: Resuscitation and Stabilization of the Polytraumatized Patient 4th Annual Current Solutions in Orthopaedic Trauma, Musculoskeletal Research Foundation, Orlando, Florida 16-19.11.2006
162. Pape HC European polytrauma study on the management of femur fractures
75 Curriculum Vitae, HC Pape MD, FACS
7th World Congress on Trauma, Shock, Inflammation and Sepsis Munich, Germany, 13-17.3.2007
163. Pape HC Damage Control for Dummies: When is it OK Not to Fix Fractures Acutely? 7th Annual AAOS/OTA Trauma Course: Current Management Strategies, Technical Pearls, and Optimizing Outcomes for Common Fractures, St Augustine FL, 12-15.4.2007
164. Pape HC Impact of the Method of Initial Stabilization For Femoral Fractures in Polytrauma Patients At Risk For Complications (Borderline Patients) – A Prospective Randomized Analysis By the EPOFF Study Group 127th Annual Meeting of the American Surgical Association, Colorado Springs CO, 26.4.2007
165. Pape HC New Trends in femoral shaft fractures; Timing of fixation AO Education Symposium, Florence Italy, 13.5.2007
166. Pape HC Increased risk of acute lung injury associated with initial intramedullary femoral nailing in polytrauma patients at risk for complications 1st Joint Congress of the European Association for Traumaand Emergency Surgery (EATES) and the European Trauma Society (ETS), Graz Austria, 23-26.5.2007
167. Pape HC Development of the concepts of damage control orthopaedics in polytrauma patients Canadian Orthopaedic Association, Halifax Canada, 1.6.2007
168. Pape HC AO History, Principles and Indications for Fracture Treatment AO North America Operating Room Personnel Principles Course, Pittsburgh PA 22-23.6.2007
169. Pape HC Damage Control Orthopaedics: when is it OK to nail femurs? Pennsylvania Orthopaedic Trauma Symposium, Philadelphia PA, 7-8.9.2007
170. Pape HC Keynote Lecture: Damage Control Orthopaedics X Current Principles and Controversies in Orthopaedic Trauma, Dublin Ireland, 13-14.9.2007
171. Pape HC Early Intramedullary Femoral Fixation vs External Fixation in Polytrauma Orthopaedic Trauma Association 2007 Annual Meeting, Denver CO, 17-20.10.2007
172. Pape HC Assessment of Systemic Proinflammatory Mediator Release following Skeletal Surgery Orthopaedic Trauma Association 2007 Annual Meeting, Denver CO, 17-20.10.2007
173. Pape HC Case Presentations - Damage Control Orthopaedics, Moderator Orthopaedic Trauma Association 2007 Annual Meeting, Denver CO, 17-20.10.2007
174. Pape HC Damage Control Orthopaedics 2008 Annual John R. Border Memorial Lecture
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State University at New York Buffalo, Department of Surgery, 16.1.2008
175. Pape HC Damage Control Orthopaedics; Treatment of Nonunions 2008 Caribbean Trauma Update, Cancun, Mexico, 7-10.2.2008
176. Pape HC Initial fixation method for femoral shaft fractures in polytrauma 75th Annual Meeting, American Academy of Orthopaedic Surgeons, San Francisco CA 5.3.2008
177. Pape HC Damage Control Orthopaedics, Alan E. Freeland Research Lecture Series University of Mississippi Medical Center, Jackson, Mississippi 27.5.2008
178. Pape HC Damage Control Orthopaedics – Borderline Patients Polytraumakurs 2008, Klinik für Unfallchirurgie, Universitätsklinikum Essen, Germany 12.6.2008
179. Pape HC New Concepts for fracture fixation in the polytrauma patient Osteosynthesis & Trauma Care Foundation 2008 Annual Meeting, Nice, France 27.6.2008
180. Pape HC All Femur Fractures Require Damage Control Orthopaedics Osteosynthesis & Trauma Care Foundation 2008 Annual Meeting, Nice, France 27.6.2008
181. Pape HC Clearing Polytrauma Patients for Major Surgery: Which Parameters Are the Best? Orthopaedic Trauma Association 2008 Annual Meeting, Denver, Colorado, 16.10.2008
182. Pape HC The Marketing Morass of Bone Substitutes: How Do I Pick? Orthopaedic Trauma Association 2008 Annual Meeting, Denver, Colorado, 18.10.2008
183. Pape HC Treatment of Nonunions and Post-traumatic Deformities Grand Rounds Visiting Professor, UT Southwestern, Dallas, Texas, 5.11.2008
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