Rabbit Anti-Human Phospho-Shb (Y246) Polyclonal antibody (DPABH-01360) This product is for research use only and is not intended for diagnostic use.
PRODUCT INFORMATION
Product Overview Rabbit Polyclonal to Phospho-Shb (Y246).
Specificity This antibody detects endogenous levels of Shb protein only when phosphorylated at Y246.
Target Phospho-Shb
Immunogen Synthesized peptide derived from human Shb around the phosphorylation site of Y246.
Isotype IgG
Source/Host Rabbit
Species Reactivity Human, Mouse
Purification This antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conjugate Unconjugated
Applications WB, ELISA
Molecular Weight 55 kDa
Format Liquid
Concentration Lot specific
Buffer PBS containing 50% glycerol and 0.5% BSA
Preservative 0.02% Sodium Azide
Storage Store at -20°C, and avoid repeat freeze-thaw cycles.
Warnings For research use only.
BACKGROUND
Introduction Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating
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Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic- FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.
Keywords SHB;Src homology 2 domain containing adaptor protein B;SHB (Src homology 2 domain containing) adaptor protein B;SHB adaptor protein (a Src homology 2 protein);SH2 domain- containing adapter protein B;SHB adaptor protein (a Src homology 2 protein);SHB (Src homology 2 domain containing) adaptor protein B;bA3J10.2;RP11-3J10.8
GENE INFORMATION
Entrez Gene ID 6461
UniProt ID Q15464
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Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved