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Rabbit Anti-mu /FITC Conjugated antibody

SL17900R-FITC

Product Name: Anti-mu Crystallin/FITC Chinese Name: FITC标记的CRYM蛋白抗体 CRYM; CRYM_HUMAN; Crystallin mu; DFNA 40; DFNA40; Ketimine reductase; Mu crystallin homolog; Mu-crystallin homolog; NADP regulated thyroid hormone Alias: binding ; NADP-regulated thyroid-hormone-binding protein; OTTHUMP00000115878; THBP; Thiomorpholine carboxylate dehydrogenase. Organism Species: Rabbit Clonality: Polyclonal React Species: Human,Mouse,Rat,Pig,Cow,Sheep,Cat, ICC=1:50-200IF=1:50-200 Applications: not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. Molecular weight: 34kDa Form: Lyophilized or Liquid Concentration: 1mg/ml immunogen: KLHwww.sunlongbiotech.com conjugated synthetic peptide derived from human mu Crystallin Lsotype: IgG Purification: affinity purified by Protein A Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year Storage: when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. background: are separated into two classes: taxon-specific and ubiquitous. The former Product Detail: class is also called phylogenetically-restricted crystallins. The latter class constitutes the major of vertebrate eye lens and maintains the transparency and refractive index of the lens. This encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010]

Function: Binds thyroid hormone. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors.

Subcellular Location: Cytoplasm.

Tissue Specificity: Expressed in neural tissue, muscle and kidney.

Similarity: Belongs to the ornithine cyclodeaminase family.

Database links:

Entrez Gene: 1428 Human

Entrez Gene: 505167 Cow

Entrez Gene: 12971 Mouse

Entrez Gene: 117024 Rat

Omim: 123740 Human

SwissProt: Q14894 Human

SwissProt:www.sunlongbiotech.com O54983 Mouse

SwissProt: Q9QYU4 Rat

Unigene: 924 Human

Unigene: 9114 Mouse

Unigene: 24561 Rat

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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