PORTABLE PRODUCTION MIXER-RECORDER Legal Notices Manual Conventions Product Specifications and Features Are Subject to Change Without Prior Notification
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Transferrin Receptor Mrna Interactions Contributing to Iron Homeostasis
Downloaded from rnajournal.cshlp.org on October 1, 2021 - Published by Cold Spring Harbor Laboratory Press Transferrin receptor mRNA interactions contributing to iron homeostasis DHWANI N. RUPANI and GREGORY J. CONNELL Department of Pharmacology, University of Minnesota, Minneapolis, Minnesota 55455, USA ABSTRACT The transferrin receptor is the primary means of iron importation for most mammalian cells and understanding its regulatory mechanisms is relevant to hematologic, oncologic, and other disorders in which iron homeostasis is perturbed. The 3′ UTR of the transferrin receptor mRNA contains an instability element that is protected from degradation during iron depletion through interactions of iron regulatory proteins (IRPs) with five iron-responsive elements (IREs). The structural features required for degradation and the site of IRP binding required for in situ protection remain unclear. An RNA-CLIP strategy is described here that identifies the predominant site of IRP-1 interaction within a nontransformed primary cell line. This approach avoided complications associated with the use of elevated concentrations of protein and/or mRNA and detected interactions within the native environment of the mRNA. A compensatory mutagenesis strategy indicates that the instability element at minimum consists of three non-IRE stem–loops that can function additively, suggesting that they are not forming one highly interdependent structure. Although the IREs are not essential for instability, they enhance instability when IRP interactions are inhibited. These results are supportive of a mechanism for a graded response to the intracellular iron resulting from a progressive loss of IRP protection. Keywords: endonuclease; iron homeostasis; iron-responsive elements; iron regulatory proteins; transferrin receptor INTRODUCTION the CAGWGH consensus sequence, where W is A or U and H is A, C, or U (for review, see Kuhn 2015). -
Narrative, Visual Model and Dragon Culture: a Narrative Analysis of Value Presentation in Two Movies Preferred by Chinese Adolescents
DOCUMENT RESUME ED 431 677 SO 030 813 AUTHOR Jin, He TITLE Narrative, Visual Model and Dragon Culture: A Narrative Analysis of Value Presentation in Two Movies Preferred by Chinese Adolescents. Research Bulletin 98. INSTITUTION Helsinki Univ. (Finland). Dept. of Education. ISBN ISBN-951-45-8342-6 ISSN ISSN-0359-5749 PUB DATE 1998-00-00 NOTE 239p.; Academic Dissertation, University of Helsinki (Finland). AVAILABLE FROM Dept. of Education, P.O. Box 39 (Bulevardi 18), 00014 University of Helsinki, Finland. PUB TYPE Collected Works Serials (022)-- Dissertations/Theses (040) EDRS PRICE MF01/PC10 Plus Postage. DESCRIPTORS *Adolescents; Comparative Analysis; *Criticism; *Cultural Context; *Films; Foreign Countries; Models; Secondary Education; Secondary School Students; Semiotics; Student Surveys; *Values IDENTIFIERS *China; Film Genres; Narrative Text; *Visual Representation ABSTRACT A narrative study was ccnducted of the visual models in two movies preferred by Chinese adolescents in two schools (n=152) . The two movies studied were "Three Decisive Campaigns" (A Chinese Trilogy) and the American science fiction movie, "Jurassic Park." The modified approach from Bandura's modeling theory and film semiotics was used to derive amore adequate explanation of modeling from the relationships among narrative, culture, and values. Results indicated that the narrative and cultural characteristics of the film characters at the levels of text, structure, and logic provide some basic prerequisites for model selection and preference. From the viewpoint of modeling, characters in the movies provide three main kinds of knowledge for vicarious learning:(1) social role norm;(2) the environmental contingency; and (3) the vicarious reinforcing experience. Findings suggest that different genres not only influence what kinds of value models are presented, but also how they are presented and how theyare able to convince the viewer. -
Premium Portable Mixer-Recorder User Guide
PREMIUM PORTABLE MIXER-RECORDER USER GUIDE Legal Notices Manual Conventions Product specifications and features are subject to change without prior notification. SYMBOL DESCRIPTION This symbol is used to show the order in which you select menu Copyright© 2020 Sound Devices, LLC. All rights reserved. commands and sub-options, such as: Main Menu > Outputs > This product is subject to the terms and conditions of a indicates you press the Menu button for the Main Menu, then software license agreement provided with the product, and scroll to and select Outputs by pushing the Knob. may be used in accordance with the license agreement. [ ] This symbol is used to convey selectable menu items. This document is protected under copyright law. An authorized licensee of this product may reproduce this publication for the * This symbol is used to convey factory default settings. licensee’s own personal use. This document may not be reproduced A plus sign is used to show button or keystroke combinations. For or distributed, in whole or in part, for commercial purposes, such instance, Ctrl+V means to hold the Control key down and press as selling copies or providing educational services or support. the V key simultaneously. This also applies to other controls, This document is supplied as a technical guide. Special care + such as switches and knobs. For instance, MIC+HP turn means has been taken in preparing the information for publication; to slide and hold the MIC/TONE switch left while turning the Headphone (HP) knob. METERS+SELECT means to hold the however, since product specifications are subject to change, METERS button down as you press the SELECT knob. -
New Bay Minette Elementary Near Completion
Covering all of Baldwin County, AL every Friday. Legends in concert PAGE 15 High school football The Baldwin Times PAGE 22 OCTOBER 11, 2019 | GulfCoastNewsToday.com | 75¢ New Bay Minette Elementary near completion Spanish Fort Fall Concert By TINA COVINGTON Sunday This time next week, stu- dents will be sitting in their Submitted classrooms at the brand-new Bay Minette Elementary SPANISH FORT — School. Construction crews The city of Spanish Fort are completing their punch will hold its Fall Concert lists this week, and teachers and Art Guild Show on will begin the move Friday. Sunday, Oct. 13, starting The grammar school has at 5 p.m. at the Spanish come a long way from its hum- ble one-room school house, SEE CONCERT, PAGE 7 to the old Scout Cabin Park building in 1903, the current school building in the early 1920s to this new facility in 2019. BRATS drops The new BMES features from Shrimp SEE NEW, PAGE 4 SUBMITTED PHOTO Festival New shuttle Officials host ribbon cutting, grand opening at Kaishan in Loxley stops announced STAFF REPORTS New shuttle stops have been announced for this weekend’s Shrimp Festival since Baldwin Regional Area Transit System an- nounced it would not service the annual fes- tivities. SEE BRATS, PAGE 6 JOHN UNDERWOOD / STAFF PHOTO Voting now The Kaishan group held a ribbon cutting with the Central Baldwin Chamber of Commerce on Friday, Oct. 4 at its new U.S. corporate headquarters open for Gulf and manufacturing facility in Loxley. Pictured with Kaishan officials are Baldwin County Commissioner Joe Davis, Rep. -
Premium Portable Mixer-Recorder
PREMIUM PORTABLE MIXER-RECORDER USER GUIDE Legal Notices Manual Conventions Product specifications and features are subject to change without prior notification. SYMBOL DESCRIPTION This symbol is used to show the order in which you select menu Copyright© 2020 Sound Devices, LLC. All rights reserved. commands and sub-options, such as: Main Menu > Outputs > This product is subject to the terms and conditions of a indicates you press the Menu button for the Main Menu, then software license agreement provided with the product, and scroll to and select Outputs by pushing the Knob. may be used in accordance with the license agreement. [ ] This symbol is used to convey selectable menu items. This document is protected under copyright law. An authorized licensee of this product may reproduce this publication for the * This symbol is used to convey factory default settings. licensee’s own personal use. This document may not be reproduced A plus sign is used to show button or keystroke combinations. For or distributed, in whole or in part, for commercial purposes, such instance, Ctrl+V means to hold the Control key down and press as selling copies or providing educational services or support. the V key simultaneously. This also applies to other controls, This document is supplied as a technical guide. Special care + such as switches and knobs. For instance, MIC+HP turn means has been taken in preparing the information for publication; to slide and hold the MIC/TONE switch left while turning the Headphone (HP) knob. METERS+SELECT means to hold the however, since product specifications are subject to change, METERS button down as you press the SELECT knob. -
Official League Stats 2018 Season Index
OFFICIAL LEAGUE STATS 2018 SEASON INDEX 01 | CHAMPIONSHIP STATS AND RESULTS ......................................... 3 2018 PFL WORLD CHAMPIONS .......................................................................... 3 2018 PFL CHAMPIONSHIP RESULTS................................................................... 3 2018 PFL CHAMPIONSHIP SUPERLATIVES .......................................................... 4 SEEDS - CHAMPIONSHIP APPEARANCES ........................................................... 4 SEEDS - CHAMPIONSHIPS WON ........................................................................ 4 02 | LEAGUE STATS ......................................................................... 5 STOPPAGE PERCENTAGE ................................................................................... 5 STOPPAGE BREAKDOWN ................................................................................... 5 FIGHTING TWICE IN ONE NIGHT ........................................................................ 5 FIGHT SCHEDULING - SUCCESS RATE ................................................................ 5 NATIONS REPRESENTED ................................................................................... 5 03 | CAGENOMICS .......................................................................... 6 SINGLE FIGHT LEADERS ................................................................................... 6 SEASON LEADERS ........................................................................................... 9 04 | OFFICIAL LEAGUE RESULTS -
Student Handbook 2018-2019
Duncan Middle School 601 Chisholm Trail Parkway Duncan, OK 73533 (580) 470-8106 Fax (580)470-8743 www.duncanps.org Student Handbook 2018-2019 Student Handbook The Student Handbook is placed in the hands of the student to serve as a guide while at Duncan Middle School, and to lessen problems and difficulties. It is hoped that the handbook will be studied carefully by students and parents so they may understand the policies and procedures of Duncan Middle School. Many of the policies set down are governed by state law or are directives of the Oklahoma State Board of Education. Many are Duncan Board of Education policies; some are customs or traditions and may be amended as the need arises. We seek to provide opportunities for our students to succeed in a safe learning environment. Welcome Every student is a member of a team dedicated to making Duncan Middle School one of the finest in our nation. The entire staff proudly joins you in accepting the challenge as you strive to achieve your highest potential. The answers to many of the questions you might have about DMS are included in this handbook. We, the faculty, will strive in every way possible to make this one of the best years for you, the student. Rodney Strutton, Principal Christy Jarboe, Assistant Principal Tim Hightower, Assistant Principal Building Hours 7:00 a.m…………………………………………………..Doors Open 7:00 a.m.Office and cafeteria open-limited hall access 3:30 p.m.Office closes (last school day of week – Office closes at 3:20 p.m.) 3:30 p.m………………………………………………..Doors Locked Summer Hours – 7 a.m.