ASX Announcement

Regeneus’ osteoarthritis cell therapy, HiQCell®, to launch in Singapore, under leading sports physician, Dr Patrick Goh Sydney, Australia – 23 September 2014

Highlights

• HiQCell Regenerative Medicine Clinic to open at prestigious Camden Medical Centre in Singapore • Clinic to be led by Medical Director, Dr Patrick Goh, a leading sports and exercise medicine specialist • First treatments expected to commence in late 2014 • Announcement signals the impending launch of Regeneus’ first offshore treatment centre and a major milestone for the Company

Regenerative medicine company, Regeneus Ltd (ASX: RGS), today announced plans to open the HiQCell Regenerative Medicine Clinic in Singapore, and the appointment of leading specialist sports physician, Dr Patrick Goh, as Medical Director.

Through the clinic, Dr Goh will provide patients in Singapore with access to Regeneus’ HiQCell, an innovative cell therapy for the treatment of osteoarthritis, with first treatments expected to commence in late 2014. As well as assuming the role of Medical Director, at the HiQCell Regenerative Medicine Clinic, Dr Goh will become the initial treating medical practitioner for the HiQCell procedure.

Dr Goh is a leading specialist who was chief medical officer for Team Singapore during the 2000 and 2004 Olympic Games. He holds a number of positions within Singapore’s Ministry of Health, the Singapore Armed Forces and Defence Science Organisation (DSO) and the National Anti-Doping Advisory Board. Dr Goh said, “HiQCell provides a viable treatment option for mid-stage, age or impact related osteoarthritis patients who might otherwise face ongoing debilitating pain, loss of function, inability to play sport and reduced quality of life. I am very pleased to be able to offer this treatment to my patients.” The HiQCell Regenerative Medicine Clinic will be located at the prestigious Camden Medical Centre in Singapore’s premier medical services district on Orchard Road where a new state of the art cell-processing laboratory has been established.

Singapore provides a natural first overseas market for HiQCell as it is recognised as a leading edge medical services hub for both local and international patient treatments. Regeneus Commercial Development Director for Human Health, Steven Barbera, said, “We are delighted to be partnering with Dr Goh at what will be a first class medical facility within Camden Medical Centre, to deliver high quality outcomes for patients.” Regeneus CEO, Professor Graham Vesey said, “This is a very exciting announcement for Regeneus as it reports against a major milestone and highlights the first location for treatment of HiQCell outside of Australia. It makes good sense for Regeneus from a business perspective to select Singapore as the first international location for the delivery of our HiQCell treatment, as the regulatory environment is similar to

25 Bridge Street, Pymble, NSW 2073 Ph: +61 2 9499 8010 • Fax: +61 2 9499 8020 • www.regeneus.com.au • ABN 13 127 035 358

what we’re used to in Australia and the standard of care is very high.”

The HiQCell treatment involves harvesting a small amount of a patient’s own stem cells from their adipose (fat) tissue and after separating and concentrating the regenerative cells these are re-injected in osteoarthritic-affected joints such as knees, hips and ankles. The HiQCell treatment, which aims to reduce inflammation and repair damaged tissue is carried out under the supervision of the treating medical practitioner. HiQCell has been used to treat more than 500 patients and over 1,000 arthritic joints. The cell therapy procedure is supported by safety data from a randomised controlled clinical trial and long-term safety and efficacy data is tracked through Australia’s first Joint Registry for stem cell therapy. For more information on HiQCell please call 1300 573 669 or go to www.hiqcell.com.au. ENDS

About Regeneus:

Regeneus Ltd (ASX: RGS) is a Sydney-based ASX listed regenerative medicine company that develops and commercialises stem cell and other biological therapies for the human and veterinary health markets with a focus on musculoskeletal and oncology conditions. www.regeneus.com.au www.hiqcell.com.au

About Dr Patrick Goh:

Dr Goh is a registered specialist in Sports Medicine, practicing at Sports Medicine International, part of the Orthopaedics International group in Singapore. He received his medical degree from the National University of Singapore in 1984 before going on to further studies in sports medicine in the USA.

A clinician for 30 years, he worked previously with the rehabilitation medicine department of Singapore General Hospital, and the Singapore Sports Council’s (SSC) Sports Medicine and Research Centre, where his patients ranged from recreational athletes to the country’s top sportsmen and women. He was Chief Medical Officer for Team Singapore for the 2000 and 2004 Olympic Games, and team physician to numerous regional games.

Dr Goh pioneered the use of musculoskeletal ultrasound as an in-clinic tool for evaluation and imaging- guided treatment of sports and musculoskeletal injuries, in particular, ultrasound-guided Extracorporeal Shock-Wave Therapy (ESWT). In 2008, leveraging on his familiarity with musculoskeletal ultrasound, he became the first sports physician in Singapore to use Platelet-Rich Plasma (PRP) for the targeted treatment of sports injuries. His work in this area led to numerous invitations to speak on this topic at home and internationally, as he continues to have an ongoing interest in biological solutions for musculoskeletal and sports injuries.

In addition to his private sports medicine practice, Dr Goh is currently Co-Chair of the Sports Medicine Subspecialty Training Committee under the Ministry of Health, and is an examiner for the Sports Medicine Advanced Specialty Training exams. He is Deputy Chairman for the institutional review board of the Singapore Armed Forces and the Defence Science Organisation (DSO). Dr. Goh also holds appointments as Chairman of the National Anti-Doping Advisory Board for Singapore and Chairman of the South-East Asian Regional Anti-Doping Organisation (SEARADO). He is an elected board member of the Institute of National Anti-Doping Organisation (iNADO). www.ortho-intl.com/index.php/dr-patrick-goh

About Camden Medical Centre:

Camden Medical Centre’s exclusive, multi-disciplinary community includes leading medical specialists and healthcare professionals in , , obstetrics and gynaecology, dentistry, family

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25 Bridge Street, Pymble, NSW 2073 Ph: +61 2 9499 8010 • Fax: +61 2 9499 8020 • www.regeneus.com.au • ABN 13 127 035 358

medicine, , aesthetic medicine, neurology, psychiatry, rehabilitation therapy and sports medicine.

At Camden, every medical clinic and healthcare centre is committed to providing the quality care and premium service. This provides peace of mind to all local and international patients who are seeking world- class healthcare. www.camdenmedical.com

Contacts and further information:

Investors: Sandra McIntosh Company Secretary Regeneus Ltd T: +61 2 9499 8010 E: [email protected] or go to www.regeneus.com.au

Practitioner and Patient Enquiries: Steven Barbera Commercial Development Director - Human Health Regeneus Ltd T: +61 2 9499 8010 E: [email protected]

Mr Bou Leong Lai Director – Regeneus South East Asia Pte Ltd T: +65 9617 8501 E: [email protected]

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25 Bridge Street, Pymble, NSW 2073 Ph: +61 2 9499 8010 • Fax: +61 2 9499 8020 • www.regeneus.com.au • ABN 13 127 035 358