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Endo 2016 Preview THE YEAR OF ENDOCRINOLOGY: OBESITY MARCR H 20166 THTHE LELEADADINING MMAGAG ZIZ NENE FORR ENDNDOCO RIR NONOLOGISTS HOW ENDOCRINE SCIENCE IS ADDRESSING THE OBESITY EPIDEMIC: ✔ Bariatric surgery as cancer prevention LLivingiving ✔ Putting natural products under the microscope ✔ How does obesity affect the epigenome…and the next generation? Large ✔ How to talk to obese patients about weight EENDONDO 22016016 PPREVIEW:REVIEW: What to expect from the Early Careers Forum LLABAB NNOTESOTES QQ&A&A Daniel Bernard, PhD, on FSH, budgets, and “new” mice Proud to be one of the nation’s largest comprehensive endocrinology programs. We’re one of the largest multidisciplinary programs to offer comprehensive evaluation and management of pediatric obesity. With cutting-edge research and a clinical and academic affiliation with UT Southwestern Medical Center, our diabetes program is one of the largest in the nation and was the first to receive the Disease Specific Care Certification for Diabetes by The Joint Commission. Home to the only transgender pediatric program in the southwestern United States, our endocrinology team is making major strides in health care. Visit childrens.com/excellence to learn more. IN THIS ISSUE MARCH 2016 2 | FROM THE EDITOR COVER STORY Covering obesity from a variety of angles. 10 | Lose 3 | PRESIDENT’S VIEWPOINT Using the Society Centennial to focus Weight, Avoid on the obesity epidemic. Cancer? 4 | DASHBOARD The evidence that bariatric surgery Highlights from the world of reduces the risk of cancer continues endocrinology. to mount — adding to the reasons that severely obese 5 | WHY ENDOCRINOLOGY? patients should consider Lifestyle as Medicine this option for weight loss. BY KARL NADOLSKY, MD BY ERIC SEABORG 7 | TRENDS & INSIGHTS A look at the latest research 29 | PRACTICE RESOURCES ADVISE & CONSENT Obesity is such a sensitive issue that many physicians avoid discussing it. Here are some tips on the right (and wrong) ways to broach the subject BY ERIC SEABORG 32 | LABORATORY NOTES FEATURE FEATURE FEATURE Q&A: SONGS IN A KEY OF GNRH Endocrine News talks with Daniel EENDONDO 22016016 16 21 The 26 PREVIEW: Bernard, PhD, about his obsession | Natural | | with FSH, what he would do if budget Selections Epigenetics Jump weren’t an issue, and why he thinks mice are the king of the research lab. Dietary supplements have of Obesity Starting an BY MELISSA MAPES become the “snake oil” of the 21st Century, even though Obesity appears to change Endocrinology 35 | ADVOCACY some natural products have genetic expression in ways Career Assessing barriers and standard positive benefi ts. With a that favor the development Endocrine News practices for hypoglycemia; Obama's multi-million-dollar boost of diabetes and other spoke with four FY2017 budget disappoints; and NIH from the National Institutes of conditions — changes that of this year’s Early Career Forum on new advances, budget issues. Health, institutions throughout might even be passed on to speakers to get a sneak peek the next generation. of their presentations at ENDO the country are diving in to 37 | INTOUCH research the health benefi ts of 2016 in Boston. BY ERIC SEABORG EndoExpo in Boston; Society natural products. BY DEREK BAGLEY VIPs visit DC offi ces; Pfi zer off ers BY GLENDA FAUNTLEROY new endocrinology award; and remembering Marion Sewer. 43 | CLASSIFIEDS Career opportunities Follow us on Twitter: @Endocrine_News www.endocrine.org ENDOCRINE NEWS | MARCH 2016 | 1 MARCH 2016 FROM THE EDITOR Examining the Obesity THE LEADING MAGAZINE FOR ENDOCRINOLOGISTS Epidemic from a Variety of Angles Endocrine News is a registered trademark owned by the Endocrine Society. Endocrine News informs and engages the global S WE DIVE DEEPER INTO THE YEAR OF ENDOCRINOLOGY endocrine community by delivering timely, accurate, and trusted content covering the practice, research, and Awe fi nd ourselves in March which is devoted to obesity and obesity- profession of endocrinology. related endocrine disorders. Of which there are many. Our cover story — “Lose Th e mission of the Endocrine Society is to advance excellence in endocrinology and promote its essential and Weight, Avoid Cancer?” (p. 10) — is a tantalizing topic to be sure: bariatric surgery integrative role in scientifi c discovery, medical practice, as a method to avoid cancer. Despite the simplicity of the title, is it really that easy? and human health. “One in fi ve women’s cancer deaths in the United States could be prevented by just President: Lisa H. Fish, MD diet and nutrition,” Susan C. Modesitt, MD, a professor at the University of Virginia lisafi [email protected] President-Elect: Henry M. Kronenberg, MD in Charlottesville tells writer Eric Seaborg, adding that “Th ree out of the four big [email protected] cancers in terms of incidence for women —breast, uterine, and colorectal cancer — Past President: Richard J. Santen, MD are all obesity related.” [email protected] Secretary-Treasurer: Kenneth H. Hupart, MD [email protected] From bedside back to bench, Seaborg further investigates the eff ects obesity has Chief Executive Offi cer: Barbara Byrd Keenan, FASAE, CAE on genes and gene expression, specifi cally the possible implications from one [email protected] generation to the next. In “Th e Epigenetics of Obesity” (p. 21), the importance Chief Publications Offi cer: Richard O’Grady, PhD, CAE of epigenetic research is highlighted, especially in terms of potential treatments [email protected] Editor: Mark A. Newman for obesity and its co-morbidities. According to Rebecca Simmons, MD, at the [email protected] University of Pennsylvania, obesity researchers are excited about this promising new Associate Editor: Derek Bagley research, adding that “we are at the stage where we are thinking about [epigenetic- [email protected] Art Director/Design: Catherine Neill Juchheim, based drugs] in the way that cancer researchers thought about it a few years ago. CNJ Creative, LLC Th e tools to study it are rapidly emerging, and I think that we will probably have www.cnjcreative.com Production Manager: Cynthia Richardson the answers in the next few years.” Yet more exciting progress is taking place in the [email protected] world of endocrine research! Prepress & Printing: Cenveo Publishing Services www.cadmus.com From the lab to the doctor’s offi ce, Seaborg explores a delicate issue that hasn’t been Endocrine News® is published 12 times a year addressed very much and that’s how to communicate with patients about their by the Endocrine Society, 2055 L Street, NW, Suite 600, Washington, DC 20036 obesity (“Advise & Consent,” p. 29). It’s a sensitive topic but for true doctor/patient Phone 202-971-3636 • Fax 202-736-9708 communication to be benefi cial, it’s a topic that must be discussed. It’s certainly not www.endocrine.org. something that can be left unsaid, especially when the patient’s health is directly Print ISSN 2157-2089 Online ISSN 2157-2097 Copyright © 2016 by the Endocrine Society. related to their weight. All rights reserved. • Please send letters to the editor, comments, and suggestions for As we leave the doctor’s offi ce and the lab, we take a quick venture to the grocery Endocrine News® to [email protected]. store’s vitamin aisle for “Natural Selections” (p. 16), Glenda Faunterloy’s examination • Product print and product online display advertising, by Pharmaceutical Media, Inc., contact Joe Schuldner, of the phenomenon of dietary supplements. Th e National Institutes of Health has [email protected], or John Alberto, [email protected]. • For classifi ed print advertising by Pharmaceutical Media, Inc., gotten involved and is funding several research facilities around the country with a Dan Simone, [email protected] multi-million-dollar investment. Th ese products are viewed as medicine or medical • For classifi ed online advertising by [email protected] Th e statements and opinions expressed in Endocrine News® are those treatments by a vast majority of the public, so a deeper understanding of their of individual authors and do not necessarily refl ect the views of the Endocrine Society. actual benefi ts is important. Advertising appearing in this publication does not constitute endorsement of its content by Endocrine News or the Endocrine Society. And there is even more exclusive content at www.endocrinenews.org as well as at the Centennial site at www.escentennial.org. — Mark A. Newman, Editor, Endocrine News 2 | MARCH 2016 | ENDOCRINENEWS.ORG PRESIDENT’S VIEWPOINT Centennial Focus: Recognizing the Worldwide Epidemic of Obesity HIS MONTH, THE CENTENNIAL CALENDAR WILL New features at ENDO 2016: Tfocus on obesity. Th is growing epidemic has been X “Respect the Science” Campaign – in order for ENDO an area of focus for the Society since it was the Presidential 2016 to present cutting-edge science, attendees need theme for ENDO 2004. Th en President, the late E. Chester to respect their colleagues by eliminating the rampant Ridgway sought to bring the collective brainpower of our picture taking that occurs at scientifi c meetings. We membership to focus on what at the time was considered will launch a campaign of reminders that we are all a secondary risk factor related to endocrine disease. Fast responsible for ensuring that scientists who are sharing forward 12 years and obesity is recognized not only as a their cutting-edge data do not need to be concerned that worldwide epidemic with one in three adults obese, but it will be captured before publication. a major comorbidity in the overall health of people with X As a way to give back to the local community, the Society endocrine disorders. will sponsor a committee service project during ENDO In addition to featuring publications, education, and 2016 to raise funds to purchase science fair boards patient materials, the March Centennial Calendar has an for about 400 Boston area middle school students, infographic from the Facts and Figures project, which thus allowing them to participate in the Citywide shows the impact of obesity on endocrine disease and why Science Fair.
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