P O S T E R S

TUESDAY, JANUARY 29, 2008

20:00 – 22:30 Poster Session A Zone 1, Herods Forum

ABCs and MDRs

PA-1 N. Fluman, D. Cohen-Karni, E. Bibi, Israel INVESTIGATING THE COUPLING MECHANISM IN THE E. COLI MULTIDRUG TRANSPORTER, MdfA, BY FLUORESCENCE SPECTROSCOPY

PA-2 A. Lerner, S. Burdman, Y. Okon, Israel PHENOTYPE CHARACTERIZATION OF AZOSPIRILLUM BRASILENSE Sp7 ABC TRANSPORTER (wzm) MUTANT

PA-3 Y. Nataf, S. Shulami, S. Yaron, Israel, F. Stahl, Germany, R. Lamed, E.A. Bayer, T.H. Scheper, Israel, A.L. Sonenshien, USA, Y. Shoham, Israel IDENTIFICATION AND CHARACTERIZATION OF THE CARBOHYDRATE ABC TRANSPORTERS IN CLOSTRIDIUM THERMOCELLUM

PA-4 N. Sigal, O. Lewinson, S.G. Wolf, E. Bibi, Israel E. COLI MULTIDRUG TRANSPORTER MdfA IS A MONOMER

Adaptation to extreme conditions

PA-5 N. Altman-Price, S. Barak, Israel PROTEIN ACETYLATION/DEACETYLATION IN THE EXTREMELY HALOPHILIC ARCHAEON HALOFERAX VOLCANII

PA-6 L. Avrahami, A. Grabelsky, D. Engelberg, S. Braun, Israel IDENTIFICATION AND CHARACTERIZATION OF EXTREMOPHILE YEAST STRAINS

PA-7 T. Gendler, Y. Gutterman, Israel GERMINATION AND SEEDLING SURVIVAL FOLLOWING PERIODS OF DESICCATION IN SCHISMUS ARABICUS (POACEAE)

PA-8 S. Ish-Shalom, A. Lichter, Israel GENE EXPRESSION AT LOW TEMPERATURE IN THE FUNGUS BOTRYRIS CINEREA

PA-9 H. Magidovich, J. Eichler, Israel CHARACTERIZATION OF N-GLYCOSYLATION SIGNALS IN THE ARECHAEA HOLOFERAX VOLCANII

PA-10 N. Plavner, J. Eichler, Israel THE TOPOLOGY OF PROTEINS PUTATIVELY INVOLVED IN N-GLYCOSYLATION IN THE ARCHAEA HALOFERAX VOLCANII

PA-11 K. Sharabi, Israel, J. Sznajder, USA, Y. Gruenbaum, Israel SENSING AND RESPONDING TO HYPERCAPNIA IN C. ELEGANS

PA-12 A. Tetievsky, O. Cohen, L. Eli-Berchoer, Israel, G. Gerstenblith, M.D. Stern, USA, I. Wapinski, N. Friedman, M. Horowitz, Israel PHYSIOLOGICAL AND MOLECULAR EVIDENCE OF HEAT ACCLIMATION MEMORY ASSOCIATED WITH CHROMATIN MODIFICATION: A LESSON FROM THE HEART

Global warming

PA-13 I. Shamir, Y. Steinberger, Israel THE COPING OF SOIL MICROBIAL POPULATION DIVERSITY WITH GLOBAL CLIMATE CHANGE

Novel approaches of imaging

PA-14 Withdrawn

49 Poster Session A – Herods Forum (continued)

PA-15 A. Laser, O. Kot, Israel, J.H. Resau, USA, L. Mittelman, I. Tsarfaty, Israel Met-INDUCED MEMBRANE BLEBBING AND ITS ROLE IN CELL MIGRATION

PA-16 P. Goichberg, I. Milo, G. Shakhar, Israel TWO-PHOTON IMAGING OF HEMATOPOIETIC CELL MOBILIZATION FROM THE BONE MARROW OF LIVE MICE

PA-17 S. Oren, T. Shani, A. Hirshberg, G. Rechavi, N. Amariglio, L. Trakhtenbrot, Israel DEVELOPMENT OF COMBINED ANALYSIS OF MORPHOLOGY, FLUORESCENCE IN SITU HYBRIDIZATION (FISH) AND DNA PLOIDY IMAGE CYTOMETRY OF CANCER CELLS

Nuclear structure and function

PA-18 R. Barkan, A. Margalit, E. Neufeld, N. Feinstein, J. Liu, Y. Gruenbaum, Israel CE-EMERIN AND CE-MAN1 OVERLAPPING FUNCTIONS ARE REQUIRED FOR MUSCLE INTEGRITY

PA-19 M. Davidovich-Cohen, A. Margalit, E. Neufeld, N. Feinstein, Israel, B. Podbilewicz, USA, Y. Gruenbaum, Israel THE LAMIN AND LEM-DOMAIN-BINDING PROTEIN BARRIER-TO-AUTOINTEGRATION FACTOR (BAF) BLOCKS PREMATURE CELL FUSION BY REGULATING SPECIFIC GENES AND MAINTAINS ADULT MUSCLE INTEGRITY IN C. ELEGANS

PA-20 A. Fridkin, E. Kaplan, Israel, A. Penkner, V. Jantsch, Austria, Y. Gruenbaum, Israel MATEFIN/SUN-1, A NUCLEAR ENVELOPE PROTEIN, IS ESSENTIAL FOR EMBRYONIC AND GERMLINE DEVELOPMENT AND HOMOLOGOUS PAIRING IN CAENORHABDITIS ELEGANS MEIOSIS

PA-21 N. Kinor, Y. Shav-Tal, Israel ALTERNATIVE SPLICING OF A PUTATIVE TUMOR SUPPRESSOR GENE PRODUCING NUCLEAR AND NUCLEOLAR PROTEINS

PA-22 A. Mattout, N. Wiesel, S. Melcer, N. Melamed-Book, O. Medalia, Israel, U. Aebi, Switzerland, Y. Gruenbaum, Israel LAMINOPATHIC MUTATIONS INTERFERE WITH THE LOCALIZATION AND DYNAMICS OF NUCLEAR LAMINS IN C. ELEGANS

PA-23 S. Melcer, Israel, H. Hermann, Germany, Y. Gruenbaum, Israel NET-ACT PROLOGUE – A NOVEL NUCLEAR ENVELOPE PROTEIN

PA-24 S. Sultan, Israel/USA, T. Tzfira, USA, M. Elbaum, Israel MAPPING THE NUCLEAR PORE COMPLEX COMPONENTS (NUCLEOPORINS) IN PLANTS

PA-25 N. Wiesel, A. Mattout, K. Ben-Harush, Israel, H. Herrmann, Germany, U. Aebi, Switzerland, O. Medalia, Y. Gruenbaum, Israel LAMINOPATHIC MUTATIONS INTERFERE WITH THE ASSEMBLY AND STRUCTURE OF NUCLEAR LAMINS IN C. ELEGANS

Programmed cell death

PA-26 S. Amitai, I. Kolodkin-Gal, H. Engelberg-Kulka, Israel OVERPRODUCTION OF MazF CAUSES A GLOBAL CHANGE IN THE PATTERN OF PROTEIN SYNTHESIS OF ESCHERICHIA COLI

PA-27 M. Assayag, Israel, G. Gerstenblith, USA, M. Horowitz, Israel MITOCHONDRIA MEDIATED ANTI-APOPTOTIC CASCADE IS ENHANCED IN HEAT ACCLIMATED RATS

PA-28 M. Avital, R. Koren, R. Sharf, T. Kleinberger, Israel GOLGI UDPASE CONTRIBUTES TO E4orf4-INDUCED APOPTOSIS IN MAMMALIAN CELLS

PA-29 B. Ben-Shachar, D. Ginsberg, Israel REGULATION OF THE PRO-APOPTOTIC MASPIN GENE BY E2F1 ENHANCES CHEMOTHERAPY- INDUCED APOPTOSIS OF CANCER CELLS

50 Poster Session A – Herods Forum (continued)

PA-30 A. Cohen, E. Sendersky, A. Perelman, R. Schwarz, Israel A RESPONSE REGULATOR CRITICAL FOR SURVIVAL OF NITROGEN STARVATION IN THE CYANOBACTERIUM SYNECHOCOCCUS ELONGATUS

PA-31 N. Dahan, N. Moran, M. Moshelion, Israel BORON TOXICITY MECHANISM IN PLANTS MIGHT BE RELATED TO NORMOTONIC SHRINKAGE AND PROGRAMMED CELL DEATH

PA-32 V. Daniel Carmi, E. Avraham, O. Goldberger, E. Vadai, E. Tzehoval, L. Eisenbach, Israel HUMAN 1-8D GENE, A NEW PRO-APOPTOTIC GENE, IS OVEREXPRESSED IN COLON CANCER: CHARACTERIZATION OF AN ABSURD SITUATION

PA-33 A. Eisenberg-Lerner, A. Kimchi, Israel DAP-kinase REGULATES JNK SIGNALING BY BINDING AND ACTIVATING PROTEIN KINASE D UNDER OXIDATIVE STRESS

PA-34 A. Florentin, E. Arama, Israel GENERATING MOLECULAR PROBES FOR DETECTION OF CASPASE ACTIVITY IN SITU

PA-35 V. Fridman, I. Shumacher, N. Movshovich, B. Katz, L. Gheber, Israel SPINDLE MIDZONE ORGANIZATION DURING MID-ANAPHASE PAUSE INDUCED BY MUTATIONS IN KINESIN-5 MOTOR PROTEINS

PA-36 L. Gibbs, E. Arama, Israel THE ROLE OF dBRUCE, A GIANT UBIQUITIN - CONJUGATING ENZYME, IN APOPTOSIS AND SPERMATID TERMINAL DIFFERENTIATION

PA-37 M. Hallak, S. Bittner, Y. Granot, I. Nathan, Israel NOVEL NAPHTHOQUINONE COMPOUNDS, AS ANTI-LEUKEMIC AGENTS THAT MEDIATE CELL DEATH THROUGH ROS FORMATION, MITOCHONDRIAL DYSFUNCTION AND PROTEASE ACTIVATION IN MYELOID LEUKEMIC CELLS

PA-38 G. Hen, A. Gross, Israel IDENTIFICATION OF BAX-INTERACTING PROTEINS AT THE MITOCHONDRIA

PA-39 Y. Kaplan, E. Arama, Israel REGULATION OF CASPASE ACTIVATION BY THE UBIQUITIN SYSTEM DURING DROSOPHILA SPERMATOGENESIS

PA-40 I. Kolodkin-Gal, A. Gaathon, H. Engelberg-Kulka, Israel THE EXTRA-CELLULAR DEATH FACTOR (EDF): A LINEAR PENTA-PEPTIDE REQUIRED FOR mazEF-MEDIATED CELL DEATH IN ESCHERICHIA COLI

PA-41 I. Koren, A. Kimchi, Israel DEATH ASSOCIATED PROTEIN 1 (DAP1): A NEW PLAYER IN AUTOPHAGY?

PA-42 M. Lahav, E. Bitman, A. Salzberg, T. Kleinberger, Israel IDENTIFICATION AND CHARACTERIZATION OF THE SIGNAL TRANSDUCTION PATHWAY INDUCED BY THE VIRAL PROTEIN E4orf4 IN DROSOPHILA

PA-43 E. Makovitzki-Avraham, V. Daniel Carmi, E. Vadai, E. Tzehoval, L. Eisenbach, Israel ISG12 - A NOVEL PRO-APOPTOTIC GENE, OVER EXPRESSED IN BREAST CANCER

PA-44 M. Maryanovich, A. Gross, Israel THE ROLE OF BID IN INHIBITING TUMOR DEVELOPMENT

PA-45 G. Oberkovitz, I. Kamer, H. Niv, S. Rienstein, A. Aviram-Goldring, A. Gross, Israel THE ROLE OF ATM MEDIATED BID PHOSPHORYLATION IN THE DNA DAMAGE RESPONSE

PA-46 R. Pinkas-Kramarsli, S. Erlich, L. Mizrahy, T. Diskin, P. Tal-Or, O. Segev, L. Lindenboim, O. Zmira, S. Harel, J.A. Hirsch, R. Stein, E. Shohami, Israel Beclin1, AUTOPHAGY AND NEURODEGENERATION

51 Poster Session A – Herods Forum (continued)

PA-47 G. Pinto, M. Mandel, T. Barliya, Z. Hazan, G. Lavie, Israel MITOTIC CELL DEATH VERSUS MITOTIC CATASTROPHE AS DISTINGUISHED BY THE ACTIONS OF HYPERICIN AND DIMETHYL TETRAMETHOXY HELIANTHRONE IN GLIOBLASTOMA CELL LINES

PA-48 S. Polager-Modan, M. Ofir, D. Ginsberg, Israel E2F1 REGULATES AUTOPHAGY AND THE TRANSCRIPTION OF AUTOPHAGY GENES

PA-49 L. Ravid, E. Arama, Israel THE ROLE OF MITOCHONDRIAL DYNAMICS FOR CASPASE ACTIVATION IN DROSOPHILA SPERMATIDS

PA-50 S. Reef, E. Zalckvar, S. Bialik, A. Kimchi, Israel A smARF WAY TO DIE: A NOVEL SHORT ISOFORM OF p19ARF IS LINKED TO AUTOPHAGIC CELL DEATH

PA-51 E. Reem, A. Kimchi, Israel DEATH ASSOCIATED PROTEIN 1: A NEW ER STRESS REGULATED PROTEIN WITH FUNCTIONAL IMPLICATIONS IN UPR AND CELL DEATH RESPONSES

PA-52 K. Scharfstein, I. Ben-Ari, T. Maoz, R. Koren, T. Kleinberger, Israel THE INTERACTIONS BETWEEN YND1 AND CDC55 AND THEIR ROLE IN THE SIGNAL TRANSDUCTION PATHWAY INDUCED BY THE ADENOVIRUS E4orf4 PROTEIN IN YEAST

PA-53 Withdrawn

PA-54 E. Sendersky, R. Schwarz, Israel MODULATION OF CELL FATE DURING STARVATION: CHARACTERIZATION OF TOXIN- ANTITOXIN SYSTEMS IN THE CYANOBACTERIUM SYNECHOCOCCUS ELONGATUS

PA-55 L. Shachnai, Y. Zaltzman, A. Gross, Israel THE ROLE OF MITOCHONDRIAL Mtch2 IN APOPTOSIS AND EMBRYOGENESIS

PA-56 Y. Shandalov, L. Veenman, S. Leschiner, Israel, W. Kugler, M. Lakomek, Germany, M. Gavish, Israel THE TRANSLOCATOR PROTEIN MAY REGULATE THE MITOCHONDRIAL PERMEABILITY TRANSITION PORE

PA-57 A. Shekhtman, Y. Gottfried, H. Gonen, A. Ciechanover, S. Larisch, Israel LEVELS OF THE PRO-APOPTOTIC PROTEIN ARTS, ARE TIGHTLY REGULATED THROUGH THE UBIQUITIN PROTEOSOME SYSTEM, WITH XIAP-SERVING AS ITS E3-LIGASE

PA-58 Y. Shoval, S. Pietrokovski, A. Kimchi, Israel ZIPk: A UNIQUE CASE OF MURINE-SPECIFIC DIVERGENCE OF A CONSERVED VERTEBRATE GENE

PA-59 A. Tabib, A. Krispin, M. Lebendiker, D. Danieli, D. Mevorach, Israel THROMBOSPONDIN-1-N-TERMINUS DOMAIN (HEPARIN BINDING N-TERMINUS DOMAIN) INDUCES A PHAGOCYTIC STATE, AND THROMBOSPONDIN-1-C-TERMINUS DOMAIN INDUCES A TOLERIZING STATE IN DENDRITIC CELLS

PA-60 A. Vanichkin, O. Bairay, O. Shpilberg, Israel ARSENIC INDUCED APOPTOSIS IN CHRONIC LYMPHOCYTIC LEUKEMIA CELLS

PA-61 D. Darvish, Z. Malik, A. Weiss, Israel REAL TIME CHARACTERIZATION ALA-PDT INDUCED CELL DEATH IN B16 MELANOMA AND NIH3T3 FIBROBLASTS

PA-62 K. Yacobi Sharon, E. Arama, Israel GERM CELL DEATH IN DROSOPHILA

PA-63 E. Zalckvar, A. Kimchi, Israel FUNCTION-BASED SYSTEMS LEVEL ANALYSIS OF THE CELL DEATH NETWORK BY SINGLE AND DOUBLE RNAi–MEDIATED PERTURBATIONS

52 Poster Session A – Herods Forum (continued)

Systems biology and bioinformatics (biological networks)

PA-64 M. Ashkenazi, M. Moshelion, Israel SHARED TRANSCRIPTIONAL CORRELATIONS IN SEED FORMATION AND IN PLANTS RESPONSE TO DROUGHT

PA-65 O. Atias, B. Chor, D.A. Chamovitz, Israel DETECTING CONSERVED GENE EXPRESSION PATTERNS BETWEEN D. MELANOGASTER AND A. THALIANA

PA-66 A. Doncic, E. Ben-Jacob, N. Barkai, Israel NOISE RESISTANCE IN THE SPINDLE ASSEMBLY CHECKPOINT

PA-67 T. Elkan, R. Hertzan, A. Dror, R. Elkon, M. Irmler, Israel, J. Beckers, K.B. Avraham, Germany THE INTEGRATION OF A TRANSCRIPTOMIC AND PROTEOMIC APPROACHES FOR THE STUDY OF BIOLOGICAL NETWORKS IN THE INNER EAR

PA-68 N. Geva-Zatorsky, A.A. Cohen, E. Eden, Israel, A. Sigal, R. Milo, USA, N. Perzov, T. Danon, L. Cohen, U. Alon, Israel DYNAMIC PROTEOMICS IN INDIVIDUAL HUMAN CELLS IN RESPONSE TO DRUGS

PA-69 N. Habib, T. Kaplan, H. Margalit, N. Friedman, Israel A NOVEL PROBABILISTIC METHOD FOR COMPARING TRANSCRIPTION FACTORS BINDING SITE PROFILES

PA-70 G. Hornung, N. Barkai, Israel NOISE PROPAGATION AND SIGNALING SENSITIVITY IN BIOLOGICAL NETWORKS: A ROLE FOR POSITIVE FEEDBACK

PA-71 R. Itzhack, Y. Louzoun, Israel DEVELOPMENT OF THE C. ELEGANS NEURAL NETWORK

PA-72 Z. Itzhaki, H. Margalit, Israel INVESTIGATING THE HIERARCHY OF INTERACTING DOMAIN PAIRS

PA-73 A. Jaimovich, R. Rinott, H. Margalit, N. Friedman, Israel A SYSTEM LEVEL VIEW OF GENETIC INTERACTION NETWORKS

PA-74 S. Kaplan, S. Itzkovitz, E. Shapiro, Israel A UNIVERSAL MOLECULAR TIMEBOMB MECHANISM UNDERLIES TRINUCLEOTIDE DISEASES

PA-75 N. Kashtan, E. Noor, U. Alon, Israel SPONTANEOUS RAPID EVOLUTION OF MODULARITY

PA-76 R.B. Kopito, M. Elbaum, Israel SIMPLE THERMODYNAMICS UNDERLIE NUCLEOCYTOPLASMIC

PA-77 S. Levy, Israel, J. Ihmels, Israel/USA, M. Carmi, A. Weinberger, G. Friedlander, N. Barkai, Israel STRATEGY OF TRANSCRIPTION REGULATION IN THE BUDDING YEAST

PA-78 D. Lukatsky, Israel/USA, B. Shakhnovich, J. Mintseris, K. Zeldovich, E. Shakhnovich, USA STRUCTURAL SIMILARITY ENHANCES INTERACTION PROPENSITY OF PROTEINS

PA-79 A. Bren, D. Madar, E. Dekel, S. Kaplan, U. Alon, Israel NEGATIVE AUTO-REGULATION OF A TRANSCRIPTION FACTOR CAN INCREASE THE DYNAMIC RANGE OF ITS DOWNSTREAM GENES

PA-80 A. Madi, Y. Friedman, D. Roth, T. Regev, S. Bransburg-Zabary, E. Ben-Jacob, Israel DECIPHERING FUNCTION – FORM MOTIFS BY SYSTEM LEVEL ANALYSIS OF GENE EXPRESSION

PA-81 L. Nissim, T. Beatus, R. Bar-Ziv, Israel AN AUTONOMOUS SYSTEM FOR IDENTIFYING AND GOVERNING A CELL'S STATE IN YEAST

53 Poster Session A – Herods Forum (continued)

PA-82 N. Rappaport, Israel, M.J. Concalves De Sa, USA, M. Piel, France, A.W. Murray, USA, N. Barkai, Israel DISENTANGLING SIGNALING GRADIENTS GENERATED BY EQUIVALENT SOURCES

PA-83 G.H. Romano, Y. Gurevich, M. Kupiec, Israel DISSECTION OF A COMPLEX GENETIC NETWORK DETERMINING NATURAL GENETIC VARIABILITY

PA-84 M. Sheffer, Israel, M. Bacolod, F. Barany, P.B. Paty, D.A. Notterman, USA, E. Domany, Israel DNA ABERRATIONS IN COLON CANCER: THE ROLE IN TUMOR INITIATION AND PROGRESSION

PA-85 I. Soifer, A. Doncic, M. Carmi, N. Barkai, Israel SINGLE CELL ANALYSIS OF SIZE CHECKPOINT OF BUDDING YEAST

PA-86 L. Ungar, M. Kupiec, Israel GENETIC INTERACTIONS BETWEEN GENES INVOLVED IN TELOMERE LENGTH REGULATION IN SACCHAROMYCES CEREVISIAE

PA-87 I. Venger, I. Rogachev, S. Mintz, D. Ackerman, N. Raban, Y. Pilpel, A. Aharoni, Israel ROBUSTNESS OF SACCHAROMYCES CERVISIAE TO DELETION MUTATIONS AND RESPONSE TO ENVIRONMENTAL STIMULI THROUGH THE LENS OF HIGH-THROUGHPUT METABOLIC PROFILING

PA-88 N. Yosef, M. Kupiec, E. Ruppin, R. Sharan, Israel A NETWORK-BASED ANALYSIS OF PROTEIN COMPLEX EVOLUTION

54 20:00 – 22:30 Poster Session A Zone 2, Dan

Bioinformatics: from genome to proteome

PA-89 M. Akerman, M. Stark, H. David, Y. Assaraf, Y. Mandel-Gutfreund, Israel A NOVEL APPROACH FOR GENOME-WIDE MAPPING OF SPLICING FACTORS BINDING SITES

PA-90 E. Akiva, Z. Itzhaki, H. Margalit, Israel BUILT-IN LOOPS FINE-TUNE DOMAIN-DOMAIN RECOGNITION

PA-91 P. Akiva, Israel/USA, S. Pollock, A. Vaknin, T. Zekharya, L. Bazak, S. Edelheit, L. Dassa, A. Golubev, Israel, E.Y. Levanon, USA, A. Wool, G. Rechavi, Y. Cohen, Israel INDEL BASED GENOTYPING - EXPANDING THE HORIZON OF GENETIC ASSOCIATION STUDIES

PA-92 B. Dassa, S. Pietrokovski, Israel AN INTEGRATIVE STUDY OF BACTERIAL INTEIN-LIKE AUTO-CATALYTIC DOMAINS IN THEIR NATIVE BACTERIA

PA-93 H. David-Eden, Y. Mandel-Gutfreund, Israel PREDICTING DELETERIOUS MUTATIONS ON THE RIBOSOMAL RNA USING SUPPORT VECTOR MACHINES

PA-94 R. Levy, M. Edelman, V. Sobolev, Israel FROM GENE SEQUENCE TO PROTEIN FUNCTION ON THE GENOMIC LEVEL: 3D METAL- BINDING SITE PREDICTIONS FROM TRANSLATED DNA SEQUENCES

PA-95 M. Frenkel-Morgenstern, D. Tworowski, M.G. Safro, Israel REVEALING THE tRNA-BINDING AND RECOGNITION SITES OF AMINO-ACYL tRNA SYNTHETASES BY MEANS OF CORRELATED MUTATIONS ANALYSIS

PA-96 Withdrawn

PA-97 L. Klipcan, M. Frenkel-Morgenstern, M. Safro, Israel tRNA-DEPENDENT PATHWAY OF CYSTEINE BIOSYNTHESIS IS ACCOMPANIED BY INCREASE OF CYSTEINE CONTENT IN METHANOGENIC ARCHAEA

PA-98 A. Koren, N. Barkai, Israel IDENTIFICATION AND GENOMIC CHARACTERIZATION OF DNA REPLICATION TIMING MUTANTS

PA-99 T. Lahav, Israel, D. Sivam, USA, D. Rosenzweig, N. Holland, Israel, H. Volpin, The Netherlands, P. Myler, USA, D. Zilberstein, Israel COMPARATIVE TRANSCRIPTOMIC AND PROTEOMIC ANALYSIS DURING DIFFERENTIATION OF THE PARASITIC PROTEOSAN LEISHMANIA

PA-100 D. Reshef, M. Slutzky, Y. Barak, E.A. Bayer, O. Schueler-Furman, Israel FACTORS GOVERNING THE AFFINITY AND SPECIFICITY IN THE COHESIN-DOCKERIN COMPLEX

PA-101 T. Shay, Israel, W.L. Lambiv, A. Murat, Switzerland, A. Misra, B. Feuerstein, USA, R. Stupp, M.E. Hegi, Switzerland, E. Domany, Israel DNA – THE QUANTITY IS NOT ALL THAT COUNTS

PA-102 G. Stelzer, A. Harel, I. Dalah, N. Rosen, M. Shmoish, T. Iny Stein, A. Sirota, A. Madi, Y. Sole, M. Safran, D. Lancet, Israel GENECARDS: ONE STOP SITE FOR HUMAN GENE RESEARCH

PA-103 M. Yassour, T. Kaplan, A. Jaimovich, N. Friedman, Israel NUCLEOSOME POSITIONING FROM TILING MICROARRAY DATA

55 Poster Session A – Dan (continued)

Epigenetics

PA-104 A.C. Bester, B. Kerem, Israel MLV INFECTION CONFERS DNA REPLICATION STRESS AND LEADS TO PREFERENTIAL INTEGRATION OF THE VIRAL DNA INTO COMMON FRAGILE SITES

PA-105 H. Betzer, S. Shukla, I. Naumov, B. Stark, G. Avrahami, D. Luria, Y. Kodman, S. Avigad, I. Yaniv, Israel HYPERMETHYLATION AND EXPRESSION OF RASSF1A IN CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA (ALL)

PA-106 S. Epsztejn-Litman, N. Feldman, A. Gerson, Israel, J. Ueda, Y. Shinkai, Japan, H. Cedar, Y. Bergman, Israel G9a-MEDIATED DE NOVO METHYLATION IS NECESSARY AND SUFFICIENT TO PREVENT REPROGRAMMING OF EMBRYONICALLY SILENCED GENES

PA-107 S. Fraenkel, H. Cedar, Y. Bergman, Israel ALLELIC MARK AND GENE CHOICE AT THE IgkappaV LOCUS

PA-108 M.R. Gouzman, Y. Bergman, Israel EPIGENETIC REGULATION OF SOMATIC RECOMBINATION AT THE IMMUNOGLOBULIN LAMDA LIGHT CHAIN

PA-109 M. Hecht, A. Tabib, I. Keshet, H. Cedar, Israel EPIGENETIC MECHANISM OF FMR1 INACTIVATION IN FRAGILE X SYNDROME

PA-110 K. Kashkush, K. Vadim, L. Snir, Z. Kraitshtein, Israel THE EVOLUTION OF TRANSPOSABLE ELEMENTS FOLLOWING GENOME DOUBLING

PA-111 Y. Mazor, M. Kupiec, Israel STRESS ACTIVATED MAPK REGULATE TELOMERIC HETEROCHROMATIN IN S. CEREVISIAE

PA-112 A. Mosquna, R. Izhaki, R. Yaari, A. Katz, N. Ohad, Israel CHROMATIN REMODELING CONTROLS PHASE TRANSITION THROUGH PLANT EVOLUTION

PA-113 E. Ozeri-Galai, M. Schwartz, A. Rahat, B. Kerem, Israel INTERPLAY BETWEEN ATM AND ATR IN THE REGULATION OF COMMON FRAGILE SITE STABILITY

PA-114 S. Rabinovitz, R. Shemer, A. Razin, Israel THE IMPRINTING MECHANISM AT THE PRADER-WILLI/ANGELMAN SYNDROMES DOMAIN USING A TRANSGENIC SYSTEM

PA-115 C. Rosenbluh, A. Kirilov, Y. Bergman, Israel THE Dm ELEMENT, A NOVEL cis REGULATORY ELEMENT IN KAPPA LIGHT CHAIN REARRANGEMENT AND ALLELIC EXCLUSION

PA-116 M. Schwartz, M. Preiss, N. Rimon, Israel, J.P. de Villartay, France, B. Kerem, Israel INVOLVEMENT OF ARTEMIS AND XLF/CERNUNNOS NHEJ FACTORS IN RESPONSE TO REPLICATION STRESS AND FRAGILE SITE STABILITY

PA-117 S. Shukla, I. Naumov, M. Hameiri-Grossman, I.J. Cohen, S. Ash, I. Yaniv, S. Avigad, Israel METHYLATION ANALYSIS OF SPECIFIC micro-RNAs IN EWING SARCOMA

PA-118 G. Granot, N. Sikron, S. Talwara, G. Grafi, Israel MOLECULAR MECHANISMS UNDERLYING DROUGHT RESISTANCE: ZYGOPHYLLUM DUMOSUM - A PERENNIAL DESERT PLANT - AS A MODEL SYSTEM

General subjects I

PA-119 S. Adar, Z. Livneh, Israel SIMULTANEOUS ANALYSIS OF TRANSLESION DNA SYNTHESIS AND HOMOLOGOUS RECOMBINATION REPAIR IN MAMMALIAN CELLS

PA-120 N. Agmon, M. Kupiec, Israel GENE-CONVERSION MEDIATED DELETION (GCMD) INDUCED BY A DSB

56 Poster Session A – Dan (continued)

PA-121 A. Alamaru, R. Yam, A. Shemesh, Y. Loya, Israel TO EAT OR NOT TO EAT? TROPHIC BIOLOGY OF STYLOPHORA PISTILLATA LARVAE - A STABLE ISOTOPE APPROACH

PA-122 Withdrawn

PA-123 O. Alber, I. Noach, R. Lamed, L. Shimon, F. Frolow, E.A. Bayer, Israel STRUCTURAL CHARACTERIZATION OF A TYPE III COHESIN MODULE FROM THE MULTI-ENZYME CELLULOSOME COMPLEX OF RUMINOCOCCUS FLAVEFACIENS

PA-124 A. Alon, D. Fass, Israel STRUCTURE AND MECHANISM OF QSOX, EXTRACELLULAR SULFHYDRYL OXIDASE PAR EXELLENCE

PA-125 T. Ashkenazi, N. Kronfeld-Schor, Israel, H. Einat, USA DEPRESSION- AND ANXIETY-LIKE BEHAVIORS IN THE DIURNAL FAT SAND RAT INDUCED BY SHORT DAYLIGHT CYCLE OR MELATONIN INJECTIONS

PA-126 Y. Avneon, M. Gutman, E. Nachliel, Y. Tsfadia, Israel MOLECULAR DYNAMICS SIMULATIONS OF PALMITATE BINDING TO THE HUMAN Tim44 C-TERMINAL DOMAIN

PA-127 D. Bar, Israel A GENOME SCALE LOOKUP FOR HORIZONTAL GENE TRANSFER

PA-128 M. Bar, T. Sherf, Israel, I. Braslavsky, USA, D. Fass, Israel ANTIFREEZE PROTEIN SCAFFOLD FOR THE DESIGN OF SURFACE BINDING BIOMOLECULES

PA-129 S. Ouanounou, Y. Barak, R. Haimovitz, E.A. Bayer, Israel COHESIN-DOCKERIN MICROARRAY: DIVERSE SPECIFICITIES BETWEEN TWO COMPLEMENTARY FAMILIES OF INTERACTING PROTEIN MODULES

PA-130 Withdrawn

PA-131 Y. Beck, H. Potashnik, K. Hirsch, I. Hazan-Hallevy, E. Paran, Israel CAROTENOID IMPROVE ENDOTHELIAL CELL FUNCTION

PA-132 A. Behar, E. Jurkevitch, B. Yuval, Israel THE GUT BACTERIAL COMMUNITY OF THE MEDITERRANEAN FRUIT FLY (CERATITIS CAPITATA) AND ITS FUNCTIONS DURING THE DIFFERENT LIFE STAGES OF THE HOST

PA-133 A. Ben-David, G. Shoham, Y. Shoham, Israel DIRECTED EVOLUTION OF A MUTANT BETA-XYLOSIDASE TOWARDS IMPROVED OLIGOSACCHARIDES SYNTHESIS ACTIVITY

PA-134 M. Ben-David, S. Albeck, O. Dym, Y. Peleg, T. Unger, A. Branzburg, J.L. Sussman, Israel STRUCTURAL GENOMICS OF POSSIBLE VIRULENCE FACTORS FROM THE PROPHAGES IN PATHOGENIC BACTERIA

PA-135 L. Ben Avraham, E. Nachliel, M. Gutman, Y. Tsfadia, Israel MOLECULAR DYNAMICS SIMULATIONS FOR THE BINDING INTERACTIONS OF CHICKEN AND TOAD LIVER FABP WITH SMALL FATTY ACID MICELLES AT THE ALTERNATIVE-PORTAL REGION

PA-136 S. Benhamron, E. Zecharia, I. Vlodavsky, D. Mevorach, Israel HEPARANASE IS CRUCIAL FOR IN-VIVO DENDRITIC CELL TRANSMIGRATION

PA-137 L. Besser, U. Chorin, I. Sekler, M. Hershfinkel, Israel SYNAPTIC ZINC SIGNALING, MEDIATED BY A ZINC SENSING RECEPTOR, IN THE CA3 HIPPOCAMPAL REGION

57 Poster Session A – Dan (continued)

PA-138 R. Bezalel-Buch, I. Kapeller, J. Shlomai, Israel INITIATION OF THE HUMAN mtDNA REPLICATION: CONTROL OF THE L-STRAND PRIMING AT THE OL

PA-139 E. Blitz, J. Kahn, D.A. Breitel, Israel, P. Maire, France, E. Zelzer, Israel BONE RIDGE DEVELOPMENT IS REGULATED BY TENDONS AND MUSCLES

PA-140 M. Boyko, Israel MORPHO-NEUROLOGICAL PARALLELS IN THE RAT MODEL OF STROKE

PA-141 Y. Bram, S. Gilead, A. Frydman-Marom, M. Levi, I. Yanai, E. Gazit, Israel THE BETA AMYLOID AND ISLET AMYLOID POLYPEPTIDES AS A MODEL TO STUDY ASSEMBLY OF AMYLOID OLIGOMERS

PA-142 R. Bronstein, D. Segal, Israel UNRAVELING TRANSCRIPTION REGULATION BY THE Ldb-BASED TRANSCRIPTION COMPLEX

PA-143 O. Carny, E. Gazit, Israel MOLECULAR CO-EVOLUTION AND THE EMERGENCE OF LUCA

PA-144 J. Caspi, Israel, D. Irwin, USA, R. Lamed, Israel, Y. Li, USA, H.P. Fierobe, Israel, D.B. Wilson, USA, E.A. Bayer, Israel CONVERSION OF THERMOBIFIDA FUSCA FREE EXOGLUCANASES INTO CELLULOSOMAL COMPONENTS: COMPARATIVE IMPACT ON CELLULOSE-DEGRADING ACTIVITY

PA-145 S. Cohen-Krausz, S. Trachtenberg, Israel THE UNIQUE SYMMETRY AND DESIGN OF ARCHAEAL FLAGELLA

PA-146 M. Cohen-Kupervaser, R. Lichtenstein, A. Porgador, Israel IDENTIFICATION AND ISOLATION OF PEPTIDE BIOMARKERS FOR CANCER DIAGNOSIS IN BODY FLUIDS

PA-147 S.J. Cohen, I. Cohen, G. Nussbaum, Israel TOLL-LIKE RECEPTOR SIGNALING PLAYS A CRITICAL ROLE IN AUTOIMMUNE CENTRAL NERVOUS SYSTEM DISEASE

PA-148 L. David, N. Adir, Israel CRYSTALLIZATION AND STRUCTURE DETERMINATION OF THE PHYCOBILISOME COMPLEX

PA-149 A. Demishtein, Y. Barak, R. Lamed, Israel, M. Morrison, USA, E.A. Bayer, Israel STUDIES ON A DOCKERIN-CONTAINING CLOSTRIDIUM THERMOCELLUM SUBTILASE AND ITS RELATIONSHIP TO THE CELLULOSOME COMPLEX

PA-150 Y. Dikshtein, E. Okun, A. Carmely, H. Saida, G. Frei, B.A. Sela, L. Varshavsky, A. Ofir, E. Levy, M. Albeck, B. Sredni, Israel THE ORGANOTELLURIUM COMPOUND, AMMONIUM TRICHLORO(DIOXOETHYLENE-O- O’)TELLURATE, REACTS WITH HOMOCYSTEINE TO FORM HOMOCYSTINE AND DEREASES HOMOCYSTEINE LEVELS IN HYPERHOMOCYSTEINEMIC MICE

PA-151 S. Dror, M. Mor, O. Beharier, A. Moran, A. Katz, Y. Etzion, Israel REVERSE MODULATION OF ZnT-1 BY ATRIAL AND VENTRICULAR TACHYPACING IN THE ISOLATED RAT HEART

PA-152 I. Edry, D. Galiani, N. Dekel, Israel THE DUAL ROLE OF PDE3A IN OOCYTE MATURATION

PA-153 R. Efrony, E. Rosenberg, Israel PHAGE THERAPY OF CORAL DISEASE

PA-154 S. Elias, E. Banin, Israel INTERACTION BETWEEN PSEUDOMONAS AERUGINOSA AND VIBRIO CHOLERAE IN PLANKTONIC AND BIOFILM CULTURES

58 Poster Session A – Dan (continued)

PA-155 S. Elsner, D. Simian, A. Azem, Israel STRUCTURE AND FUNCTION ANALYSIS OF DNAJC19 AND MAGMAS, HOMOLOGUES OF THE YEAST Pam18 (Tim14) AND Pam16 (Tim16) MITOCHONDRIAL PROTEIN - IMPORT MOTOR COMPONENTS

PA-156 L. Feinshreiber, R. Friedrich, Israel, U. Matti, J. Rettig, Germany, U. Ashery, I. Lotan, Israel Kv CHANNELS ION INDEPENDENT EFFECT ON FREQUENCY AND CHARACTERISTICS OF FUSION EVENTS

PA-157 I. Finarov, N. Moor, M. Safro, Israel CRYSTALLIZATION AND MOLECULAR-REPLACEMENT STUDIES OF HUMAN CYTOPLASMATIC PHENYLALANYL-tRNA SYNTHETASE

PA-158 K. Muradian, Ukraine, V. Fraifeld, Israel THE ‘NEW MIGHTY’ (NUMT) HYPOTHESIS OF AGING AND LONGEVITY

PA-159 C. Gafni-Amsalem, S. Glasner, D. Zamir, J. Hirschberg, Israel TOWARDS CLONING OF ZETA, A NOVEL TOMATO MUTANT IMPAIRED IN CAROTENOID BIOSYNTHESIS

PA-160 D. Gamrasni, R. Ben Arie, M. Goldway, Israel THE EFFECTS OF PRE-STORAGE 1-MCP TREATMENT ON PEAR AT DIFFERENT RIPENING STAGES

PA-161 G. Yacov, L. Raveh, T. Kadar, S. Chapman, A. Rosner, I. Rabinovitz, R. Sahar, R. Brandeis, B.A. Weissman, E. Gilat, Israel STATUS EPILEPTICUS AND MYOCARDIAL DAMAGE FOLLOWING SARIN EXPOSURE IN THE RAT

PA-162 D. Goldman, N. Lavid, A. Schwartz, D. Danino, Y. Shoham, Israel TWO ACTIVE FORMS OF ZYMOMONAS MOBILIS LEVANSUCRASE: A UNIQUE MICROFIBRIL STRUCTURE OF THE ENZYME PROMOTES THE SYNTHESIS OF HIGH MOLECULAR WEIGHT LEVAN

PA-163 S. Gorelik, M. Ligumsky, R. Kohen, J. Kanner, Israel A NOVEL FUNCTION OF RED WINE POLYPHENOLS IN HUMANS: PREVENTION OF ABSORPTION OF CYTOTOXIC LIPID PEROXIDATION PRODUCTS

PA-164 I. Gottfried, O. Yizhar, M. Ehrlich, U. Ashery, Israel HUNTINGTIN INTERACTING PROTEIN 1 (HIP1) IS INVOLVED IN EARLY STEPS OF CLATHRIN MEDIATED ENDOCYTOSIS

PA-165 Y. Gubbay, E. Feige, B. Motro, Israel MICE DEFICIENT FOR THE SPERMATID-SPECIFIC PROTEIN, NURIT, DISPLAY NORMAL FERTILITY

PA-166 O. Haber, N. Guttmann-Raviv, R. Reshef, Israel CLASSICAL WOUND-HEALING CASCADES TRIGGER UROCHORDATE WHOLE BODY REGENERATION

PA-167 R. Hait-Darshan, Z. Malik, Israel REGULATION OF HEME SYNTHESIS AND PROTEASOMAL ACTIVITY BY COPPER IN WILSON DISEASE

PA-168 M. Hakim, D. Fass, Israel DISULFIDE BOND FORMATION IN THE CYTOPLASM? VIRAL SULFHYDRYL OXIDASES

PA-169 M. Halperin, Y. Kalechman, H. Cohen, B. Sredni, Israel THE BENEFICIAL EFFECT OF AS101 IN A RAT MODEL OF TYPE 2 DIABETES: ASSOCIATION WITH UPREGULATION OF SIRT1 PROTEIN EXPRESSION AND ACTIVITY

PA-170 M. Halpert, M. Abu-Abied, Z. Kerem, A. Perl, E. Sadot, Israel A SCREEN OF MEDICINAL PLANTS FOR NEW BIOLOGICALLY ACTIVE COMPOUNDS TARGETED TO THE CYTOSKELETON

59 Poster Session A – Dan (continued)

PA-171 L. Haviv, F. Backouche, D. Gillo, A. Bernheim-Groswasser, Israel A CYTOSKELETAL DEMOLITION WORKER: MYOSIN II ACTS AS AN ACTIN DEPOLYMERIZATION AGENT

PA-172 N. Heldman, D. Fass, Israel REGULATORY DISULFIDES OF THE SULFHYDRYL OXIDASE Ero1

PA-173 A. Hendel, Israel, N.E. Geacintov, USA, Z. Livneh, Israel IN VIVO ROLE OF DNA POLYMERASE ETA IN TRANSLESION DNA SYNTHESIS ACROSS UV-INDUCED DNA LESIONS IN HUMAN CELLS

PA-174 A. Heyman, I. Medalsy, O. Dgany, O. Bet-Or, A. Altman, D. Porath, O. Shoseyov, Israel SP1 AS A NOVEL SCAFFOLD BUILDING BLOCK FOR SELF-ASSEMBLY NANOFABRICATION

PA-175 M. Hoffmann, R. Dror, I. Petchtnikov, O. Avidan, M. Albeck, B. Sredni, Y. Nitzan, Israel A POTENTIAL ANTIMICROBIAL TREATMENT OF KLEBSIELLA PNEUMONIAE BY THE TELLURIUM COMPOUND AS101

PA-176 V. Givant-Horwitz, A. Amir, L. Cohen, Y. Shalem, H. Gutman, M. Cohen, E. Fishbine, J. Turetz, T. Kadar, S. Dachir, Israel INVOLVEMENT OF MATRIX METALLOPROTEINASES IN THE CUTANEOUS AND OCULAR RESPONSE TO SULFUR MUSTARD

PA-177 E. Inbar, I. Darlyuk, Israel, M. Suter-Grotemeyer, Switzerland, N. Holand, Israel, D. Rentsch, Switzerland, D. Zilberstein, Israel MOLECULAR CHARACTERIZATION OF ARGININE AND LYSINE TRANSPORTERS FROM LEISHMANIA DONOVANI

PA-178 M. Matto, Israel & USA, Jeffrey S. Glenn, USA, Benjamin Aroeti, Israel HEPATITIS C VIRUS CORE PROTEIN ASSOCIATES WITH DETERGENT RESISTANT MEMBRANES DISTINCT FROM CLASSICAL PLASMA MEMBRANE RAFTS

PA-179 K. Kogan, Israel DISSECTION AND RECONSTITUTION OF A COMPLEX REQUIRED FOR SORTING OF GENERAL AMINO ACID PERMEASE 1 (Gap1)

PA-180 Y. Koifman, Israel, J. Allen, USA, E. Shani, N. Ori, USA, K. Shokat, USA, G. Sessa, Israel BIOCHEMICAL AND FUNCTIONAL ANALYSIS OF A FAMILY OF PLANT PROTEIN KINASES WITH AN ATYPICAL ATP BINDING SITE

PA-181 M. Kolton, F. Shaya, A. Zehavi, A. Danon, O. Ostersetzer-Biran, Israel REDOX SWITCH: FERREDOXIN AS A NOVEL RNA-BINDING PROTEIN

PA-182 A. Kovacs, U. Gophna, Israel COMBINING TWO DNA FINGERPRINTING TECHNIQUES FOR THE STUDY OF THE INTESTINAL MICROBIOTA IN HEALTH AND DISEASE

PA-183 E. Kozela, M. Pietr, R. Levy, Z. Vogel, A. Juknat, Israel CANNABINOID REGULATION OF MICROGLIAL ACTIVITY

PA-184 S. Krauss, H.S. Gupta, J. Seto, Germany, J.D. Currey, UK, T. Landete-Castillejos, Spain, S.S. Funari, S.V. Roth, P. Fratzl, Germany INVESTIGATION OF FIBRILLAR DEFORMATION IN ANTLER USING SYNCHROTRON RADIATION

PA-185 O. Krieger, P. Oren-Giladi, D.A. Chamovitz, D. Segal, Israel MOLECULAR GENETIC ANALYSIS OF DROSOPHILA COP9 SIGNALOSOME SUBUNIT 8

PA-186 S. Lapidot, M. Dekel, S. Meirovitch, J. Fierer, T. Danieli, N. Lapidot, O. Shoseyov, Israel PRODUCTION OF NOVEL COMPOSITE BIOMATERIALS MADE FROM CELLULOSE AND RESILIN

PA-187 Y. Lavi, Israel, M.A. Edidin, USA, L.A. Gheber, Israel DYNAMIC PATCHES OF MEMBRANE PROTEINS

60 Poster Session A – Dan (continued)

PA-188 G. Lehmann, E. Segal, Israel, K. Muradian, Ukraine, V. Fraifeld, Israel TWO MITOCHONDRIA-ASSOCIATED FACTORS – GC CONTENT AND METABOLIC RATE EXPLAIN OVER 3/4 OF VARIATION IN MAMMALIAN MAXIMUM LONGEVITY

PA-189 J. Lellouche, E. Banin, A. Gedanken, Israel ANTIBIOFILM ACTIVITY OF NANOSIZED METAL FLUORIDES

PA-190 E. Lerner, M. Wolf, D. Amir, E. Haas, Israel THE MECHANISM OF PROTEIN FOLDING: COOPERATIVE OR DOWNHILL?

Host-pathogen interaction

PA-191 N. Alkan, R. Fluhr, D. Prusky, Israel AMMONIA SECRETION - A DUAL PARASITE AND HOST SIGNAL

PA-192 O. Bahar, T. Goffer, S. Burdman, Israel INVOLVEMENT OF TYPE 4 PILI IN PATHOGENICITY AND BIOFILM FORMATION OF ACIDOVORAX AVENAE SUBSP. CITRULLI

PA-193 Z. Ben-Barak Zelas, Israel, W. Streckel, H. Tschaepe, Germany, S. Yaron, Israel REGULATION OF THE EFFECTOR PROTEIN AvrA OF SALMONELLA ENTERICA

PA-194 E. Burns, G. Nussbaum, Israel TLR2 SIGNALING IN PERIODONTAL DISEASE

PA-195 A. Chernyahovsky, O. Shoseyov, Israel PLANT-INSECT COMMUNICATIONS VIA VOLATILE COMPOUNDS AND THEIR GLUCOSIDES

PA-196 N. Cohen, M. Stolarsky-Bennun, H. Amir-Kroll, R. Margalit, G. Nussbaum, M. Cohen-Sfady, M. Pevsner-Fischer, M. Fridkin, H. Bercovier, L. Eisenbach, S. Jung, I.R. Cohen, Israel PNEUMOCOCCAL CAPSULAR POLYSACCHARIDE IS IMMUNOGENIC WHEN PRESENT ON THE SURFACE OF MACROPHAGES/DENDRITIC CELLS: TLR-4 SIGNALING INDUCED BY A CONJUGATE VACCINE OR BY LPS IS REQUIRED

PA-197 M. Dori-Bachash, B. Dassa, S. Pietrokovski, E. Jurkevitch, Israel THE CELL CYCLE OF BDELLOVIBRIO BACTERIOVORUS, A PROKARYOTIC PARASITE – PREDATOR OF BACTERIA: A PROTEOMIC ANALYSIS

PA-198 S. Elhaik, D. Kafka, Y. Mizrahi, A. Porgador, Israel INVOLVEMENT OF THE MOUSE NKp46 RECEPTOR (mNCR1) IN STREPTOCOCCUS PNEUMONIA INFECTION

PA-199 Y. Geffen, E.Z. Ron, E. Rosenberg, Israel REGULATION OF RELEASE OF ANTIBACTERIALS FROM STRESSED SCLERACTINIAN CORALS

PA-200 I. Gurt, E. Katz, Israel VIRULENCE FOR MICE OF THREE PLAQUE-ISOLATES OF THE LISTER STRAIN OF VACCINIA VIRUS AND THE PROTECTION AGAINST AN ORTHOPOX VIRUS INDUCED BY THEM

PA-201 E. Hartog, D. Shachar, L. Ben Shalom, S. Yaron, Israel THE INFLUENCE OF SALICYLIC ACID ON THE ACTIVITY OF CIPROFLOXACIN AGAINST EXTRACELLULAR AND INTRACELLULAR SALMONELLA TYPHIMURIUM

PA-202 T. Luzzatto-Knaan, A. Golan, M. Yishay, I. Bilkis, A. Ion, A. Lipsky, I. Yedidia, Israel INDUCED RESISTANCE RESPONSE TOWARDS THE SOFT ROT BACTERIUM PECTOBACTERIUM CAROTOVORUM IN THE ORNAMENTAL MONOCOT CALLA LILY INVOLVE PRIMING OF ANTIMICROBIAL PHENOLICS

PA-203 A. Zauberman, S. Cohen, Y. Levy, G. Halperin, S. Lazar, B. Velan, A. Shafferman, Y. Flashner, E. Mamroud, Israel ANTIBODIES AGAINST V ANTIGEN OF Y. PESTIS AND PROTECTIVE IMMUNITY AGAINST PLAGUE: NEUTRALIZATION OF MACROPHAGE CYTOTOXICITY AS EFFECTIVE ASSAY FOR PREDICTING IN-VIVO SURVIVAL

61 Poster Session A – Dan (continued)

PA-204 S. Melech-Bonfil, G. Sessa, Israel THE INVOLVEMENT OF A TOMATO MAPKKK IN PLANT IMMUNITY

PA-205 E. Mills, K. Baruch, X. Charpantier, S. Kobi, I. Rosenshine, Israel REAL TIME ANALYSIS OF EFFECTOR TRANSLOCATION BY THE TYPE III SECRETION SYSTEM OF ENTEROPATHOGENIC E. COLI

PA-206 A. Moseri, J. Anglister, Israel STUDYING THE INTERACTION OF T-20 WITH GP120 BY NMR

PA-207 A. Moshayov, H. Koltai, I. Glazer, Israel DIFFERENTIAL GENE EXPRESSION OF RECOVERY IN THE ENTOMOPATHOGENIC NEMATODE HETERORHABDITIS BACTERIOPHORA

PA-208 Y. Nitzan, L. Magalashvili, I. Pechatnikov, Israel, H. Wexler, USA ISOLATION AND CHARACTERIZATION OF THE Omp-PA PORIN FROM PORPHYROMONAS ASACCHAROLYTICA AND ITS ROLE IN PATHOGENICITY

PA-209 E. Noah, J. Anglister, Israel THE C-TERMINAL SEGMENT OF T-20 CONTRIBUTES TO THE STABILIZATION OF THE SIX-HELIX BUNDLE FORMED WITH MATCHING gp41 N-PEPTIDE

PA-210 O. Rosen, A. Samson, J. Anglister, Israel INTERACTION WITHIN HIV-1 V3 REGION - IMPLICATION FOR PHENOTYPE CONVERSION

PA-211 D. Salomon, A. Bonshtien, Israel, C. Zhang, USA, M. Mayrose, Israel, K. Shokat, USA, G. Sessa, Israel BYPASSING Pto KINASE ACTIVITY: INSIGHTS TO THE RECOGNITION OF PSEUDOMONAS EFFECTORS

PA-212 D.B. Schlisselberg, H. Solnik-Isaac, S. Yaron, Israel CHARACTERIZATION OF THE pHD1 PLASMID OF SALMONELLA ENTERICA SEROVAR VIRCHOW

PA-213 N. Shirron, A. Lapidot, S. Yaron, Israel ADHESION AND COLONIZATION OF SALMONELLA TYPHIMURIUM ON PLANTS – THE ROLE OF BACTERIAL CELLULOSE

PA-214 M. Simovitch, H. Sasson, B. Aroeti, I. Rosenshine, Israel THE EspM1 AND EspM2 ARE REDUNDANT EFFECTORS OF ENTEROHAEMORRHAGIC E. COLI ACTIVATING THE RHOA SIGNALING PATHWAY

PA-215 M. Mayrose, Israel, S. Ekengren, USA, P. Kumar, S. Melech-Bonfil, Y. Sterlin, Israel, G. Martin, USA, G. Sessa, Israel MOLECULAR AND FUNCTIONAL ANALYSIS OF STRESS-INDUCED GRAS TRANSCRIPTIONAL ACTIVATORS IN TOMATO PLANTS

PA-216 D. Tamir-Ariel, N. Navon, S. Burdman, Israel A RECOMBINASE-IVET APPROACH REVEALED THAT citH IS REQUIRED FOR WILD TYPE LEVELS OF VIRULENE OF XANTHOMONAS CAMPESTRIS PV. VESICATORIA ON TOMATO

PA-217 A. Tovy, Israel ENTAMOEBA HISTOLYTICA DNA METHYLTRANSFERASE 2 INTERACTS WITH THE MULTI FUNCTIONAL PROTEIN ENOLASE

PA-218 M. Tzemach, Y. Houri-Hadad, G. Nussbaum, Israel INVOLVEMENT OF TOLL-LIKE RECEPTOR 2 IN THE HUMAN NEUTROPHIL RESPONSE TO PORPHYROMONAS GINGIVALIS

PA-219 T. Vider-Shalit, V. Fishbain, S. Raffaeli, Y. Louzoun, Israel PHASE DEPENDENT IMMUNE EVASION OF HERPESVIRUSES

PA-220 Z. Weissman, D. Kornitzer, Israel AN ENDOCYTIC MECHANISM OF HEME-IRON UTILIZATION IN CANDIDA ALBICANS

62 Poster Session A – Dan (continued)

PA-221 R. Yaniv, M. Ehrlich, Israel INTERNALIZATION AND INDUCTION OF APOPTOSIS BY THE IBARAKI STRAIN OF THE EPIZOOTIC HEMORRHAGIC DISEASE VIRUS

PA-222 M. Yishay, S. Bordman, T. Luzzatto, R. Ophir, I. Yedidia, Israel THE PATHOGENECITY OF VARIOUS PECTOBACTERIUM CAROTOVORUM ISOLATES FROM DICOTS AND MONOCOTS CORRELATES WITH EARLY GENOMIC DIVERGENCE

PA-223 N. Ziv, R. Yaniv, M. Ehrlich, Israel IDENTIFICATION AND CHARACTERIZATION OF TRAFFICKING MOTIFS OF THE IBARAKI VIRUS NS3 VIROPORIN

Molecular and developmental immunology

PA-224 E. Amram, S. Fishman, A. Margalit, G. Gross, Israel COUPLING CONSTITUTIVE DENDRITIC CELL ACTIVATION TO MHC-I PEPTIDE PRESENTATION THROUGH mRNA ENCODING PEPTIDE-BETA2 MICROGLOBULIN-TLR4

PA-225 H. Amram, O. Margalit, A.J. Simon, D. Givol, N. Amariglio, G. Rechavi, Israel DIFFERENT MUTATIONS IN THE Bcl-6 P53RE, CARRIED BY B-NHL PATIENTS, RESULTED IN ARTIAL INDUCTION OF Bcl-6 TRANSCRIPTION BY p53 PROTEIN

PA-226 R. Baron, A. Nemirovsky, I. Harpaz, H. Cohen, A. Monsonego, Israel IFN-gamma ENHANCES NEUROGENESIS IN WILD-TYPE MICE AND IN A MOUSE MODEL OF ALZHEIMER'S DISEASE

PA-227 Y. Carmi, Y. Reiter, Israel RECOMBINANT HUMAN ANTIBODIES WITH TCR-LIKE SPECIFICITY DIRECTED TOWARD CEA (CARCINOEMBRYONIC ANTIGEN) HLA-A2 RESTRICTED EPITOPE

PA-228 I. Cohen, S. Dotan, R.N. Apte, Israel THE N-TERMINAL PRO-PIECE OF INTERLEUKIN 1 ALPHA IS A DNA BINDING PROTEIN

PA-229 R. Dahan, N. Adir, Y. Reiter, Israel DESIGN OF DISULFIDE STABILIZATION FOR A RECOMBINANT MHC CLASS II

PA-230 A. David, L. Frishman, S. Jakubowicz, I. Wortzel, O. Perl, M. Barda-Saad, Israel DOWNREGULATION OF THE WISKOTT-ALDRICH SYNDROME PROTEINS CRUCIAL FOR ACTIN POLYMERIZATION

PA-231 Y. Fisher, A. Nemirovsky, A. Monsonego, Israel ANTIGEN SPECIFIC PATHWAY FOR T-CELL ENTRY INTO THE ALZHEIMER'S DISEASE BRAIN

PA-232 S. Fishman, E. Amram, A. Margalit, G. Gross, Israel EXPRESSION OF DNA OR mRNA ENCODING PEPTIDE-BETA2 MICROGLOBULIN-TLR4 IN MOUSE ANTIGEN-PRESENTING CELLS RESULTS IN EFFICIENT PEPTIDE PRESENTATION AND CONSTITUTIVE CELL ACTIVATION

PA-233 T. Gefen, J. Pitcovski, Israel CONSERVED EPITOPES OF AVIAN INFLUENZA ELICITED ANTIBODIES THAT RECOGNIZE THE WHOLE VIRUS

PA-234 O. Gershoni-Yahalom, B. Rager, A. Porgador, Israel HSP DERIVED PEPTIDE SERVES AS AN IMMUNOGENIC CARRIER, FOR WEST NILE VIRUS (WNV) EPITOP, IN CONJUGATED VACCINES

PA-235 D. Goldenberg, J. Pitcovski, M. Pasmanik-Chor, Israel SEQUENCE AND PHYLOGENETIC ANALYSIS OF SIGMA C PROTEIN OF AVIAN REOVIRUS ISRAELI ISOLATES

PA-236 M. Goldsmith, T. Zor, Israel PCERA-1 INHIBITS PROSTAGLANDIN E2 PRODUCTION IN LIPOPOLYSACCHARIDE STIMULATED MACROPHAGES

63 Poster Session A – Dan (continued)

PA-237 R. Hayun, S. Shpungin, M. Albeck, E. Okun, U. Nir, B. Sredni, Israel NOVEL INVOLVEMENT OF THE IMMUNOMODULATOR AS101 IN IL-10 SIGNALING, VIA THE TYROSINE KINASE Fer

PA-238 M. Hazani, O. Perl, M. Barda-Saad, Israel CHARACTERIZATION OF SIGNALING MOLECULAR COMPLEXES CRUCIAL FOR ACTIN REORGANIZATION IN T-CELLS

PA-239 M. Steinitz, I. Chezar, L. Lobl-Lavi, Y. Gil, R. Laskov, Israel RESTRICTED SPECTRUM OF SOMATIC HYPERMUTATION OF THE REARRANGED VH GENE IN ANTIBODY FORMING EBV-TRANSFORMED LYMPHOBLASTOID CELL LINE

PA-240 N. Levin, R. Ben-Shushan, A. Margalit, G. Gross, Israel DEVELOPMENT OF CTL-INDUCING GENETIC VACCINES THAT COUPLE MHC-I PEPTIDE PRESENTATION TO CD40 ACTIVATION

PA-241 Withdrawn

PA-242 M. Nagar, H. Vernitsky, Y. Cohen, D. Dominissini, Y. Berkun, G. Rechavi, N. Amariglio, I. Goldstein, Israel ACTIVATION-DEPENDENT EXPRESSION OF FOXP3 IN HUMAN CD4+CD25- T CELLS IS LIMITED AND STRICTLY REPRESSED BY DNA METHYLATION OF THE FOXP3 GENE

PA-243 H. Novak, K. Oved, Y. Reiter, Israel CD33: IS IT JUST A MYELOID MARKER?

PA-244 R. Oren, Z. Eshhar, Y. Reiter, Israel REDIRECTING T CELLS WITH CHIMERIC RECEPTORS COMPOSED OF T CELL RECEPTOR LIKE ANTIBODIES TOWARD THE TUMOR DERIVED ANTIGEN WT1 PRESENTED ON MHC COMPLEX

PA-245 A. Pato, G. Cafri, M. Lotem, A. Margalit, G. Gross, Israel COMBINING A FAST PROTOCOL FOR EX-VIVO DIFFERENTIATION OF HUMAN DENDRITIC CELLS WITH mRNA TRANSFECTION AS A NOVEL STRATEGY FOR THE GENERATION OF CANCER VACCINES

PA-246 S. Rohkin, V. Yavelsky, A. Tzikinovsky, R. Shaco-Levy, T. Amir, H. Kohn, B. Delgado, A. Rabinovich, B. Piura, Israel, I. Trakht, USA, L. Lobel, Israel NATIVE HUMAN AUTOANTIBODIES TARGETING GIPC1 IDENTIFY DIFFERENTIAL EXPRESSION IN MALIGNANT TUMORS OF THE BREAST CANCER

PA-247 B. Rosental, K. Amar, B. Rinkevich, Israel ALLOIMMUNE MEMORY IN THE SCLERACTINIAN REEF CORALS STYLOPHORA PISTILLATA AND ACROPORA HEMPRICHI

PA-248 K. Sinik, Y. Reiter, Israel STUDY OF ANTIGEN PRESENTATION USING T-CELL RECEPTORS

PA-249 R. Wolchinsky, K. Oved, Y. Reiter, Israel SIGNAL SUMMATION OF CD8+ T-CELLS FOLLOWING POST PRIMING ANTIGEN DENSITY- DEPENDANT ANERGY

Nano biology (tissue engineering and regenerative medicine)

PA-250 L. Adler-Abramovich, E. Gazit, Israel CHARACTERIZATION, CONTROLLED ASSEMBLY AND PATTERNING OF AROMATIC DIPEPTIDES NANOSTRUCTURES

PA-251 Withdrawn

PA-252 I. Cohen-Or, L. Adler-Abramovich, E. Gazit, Israel SPECTROSCOPIC AND MICROSCOPIC ANALYSIS OF THE SELF-ASSEMBLY OF AROMATIC DIPEPTIDES NANOSPHERES

64 Poster Session A – Dan (continued)

PA-253 A. Buxboim, S.S. Daube, R. Bar-Ziv, Israel SYNTHETIC GENE BRUSHES: RESPONSE OF EXPRESSION TO CROWDING AND CONFINEMENT

PA-254 N. Korin, A. Bransky, U. Dinnar, S. Levenberg, Israel MICRO-BIOREACTORS FOR CULTURE OF HUMAN EMBRYONIC STEM CELLS

PA-255 R. Orbach, A. Mahler, E. Gazit, Israel SELF-ASSEMBLED PEPTIDE-BASED HYDROGEL AS BIOCOMPATIBLE AGENT FOR DRUG DELIVERY, TISSUE ENGINEERING AND REGENERATION

PA-256 D. Reichmann, T. Karakouz, A. Vaskevich, I. Rubinstein, G. Schreiber, Israel A NOVEL APPROACH FOR SENSING PEPTIDE-NANOPARTICLE BINDING

PA-257 R. Tzezana, E. Zussman, S. Levenberg, Israel ULTRA-POROUS AND HIGHLY PERMEABLE SCAFFOLD FOR TISSUE ENGINEERING THROUGH HYDROSPINNING

PA-258 I. Yanai, E. Gazit, Israel THE USE OF SELF ASSEMBLED PEPTIDE NANOSTRUCTURES TO ENCAPSULATE MAGNETIC NANO-PARTICLES

Photosynthesis

PA-259 A. Amunts, O. Drory, N. Nelson, Israel FUNCTIONAL ORGANIZATION OF A PLANT PHOTOSYSTEM I

PA-260 J. Dinamarca, O. Kerner, Israel, D. Kaftan, Czech Republic, A. Scherz, Israel NOVEL THERMOPLASTIC CYANOBACTERIA

PA-261 D. Eisenstadt, I. Ohad, N. Keren, A. Kaplan, Israel CHANGES IN THE PHOTOSYNTHETIC REACTION CENTER II RESULTS IN NON- PHOTOCHEMICAL FLUORESCENCE QUENCHING IN THE DIATOM PHAEODACTYLUM TRICORNUTUM

PA-262 M. Haimovich, S. Kahlon, Israel, Y. Hihara, Japan, J. Lieman-Hurwitz, A. Kaplan, Israel ACCLIMATION FROM PHOTOAUTOTROPHIC TO PHOTOMIXOTROPHIC GROWTH - HOW DOES IT WORK?

PA-263 F. Salama, S. Larom, G. Schuster, N. Adir, Israel GENETIC MODIFICATIONS OF PHOTOSYSTEM II OF SYNECHOCYSTIS PCC 6803 TO PROMOTE ELECTRON TRANSFER FROM THE NATIVE ELECTRON - TRANSFER CHAIN TO AN ELECTRON ACCEPTOR MOLECULE

Plan molecular biology

PA-264 M. Abu-Abied, E. Belausov, Z. Kam, E. Sadot, Israel A NEW FAMILY OF ARABIDOPSIS SHORT MEMBRANE PROTEINS LOCALIZING TO ER, PLASTIDS, PEROXISOMES AND MITOCHONDRIA

PA-265 R. Tzulker, I. Glazer, I. Bar-Ilan, D. Holland, M. Aviram, R. Amir, Israel ANTIOXIDANT ACTIVITY, POLYPHENOL CONTENT AND RELATED COMPOUNDS IN DIFFERENT FRUIT JUICES AND HOMOGENATES PREPARED FROM 29 DIFFERENT POMEGRANATE ACCESSIONS

PA-266 D. Avisar, USA/Israel, A.I. Prokhnevsky, V.V. Peremyslov, V.V. Dolja, USA THE PLANT ACTIN-MYOSIN MOTILITY SYSTEM IN ORGANELLE TRAFFICKING AND VIRUS CELL TO CELL MOVEMENT

PA-267 M. Barak, T. Trebitsh, Israel GTP BINDING PROTEIN TYPA AND REPRODUCTIVE ORGAN DEVELOPMENT IN CUCUMBER

PA-268 R. Ben-David, Z. Peleg, W. Xie, Y. Saranga, A. Dinoor, A.B. Korol, T. Fahima, Israel IDENTIFICATION AND MAPPING OF POWDERY MILDEW RESISTANCE GENE DERIVED FROM WILD EMMER WHEAT ON THE DISTAL END OF CHROMOSOME 7AL

65

Poster Session A – Dan (continued)

PA-269 S. Bocobza, A. Adato, T. Mandel, M. Shapira, Israel, E. Nudler, USA, A. Aharoni, Israel RIBOSWITCH-DEPENDENT GENE REGULATION AND ITS EVOLUTION IN THE PLANT KINGDOM

PA-270 N. Chehanovsky, A. Mett, E. Belausov, M. Moy, S. Shen, D. Gidoni, A.A. Schaffer, Israel COMPARATIVE INTERSPECIFIC PROMOTER ANALYSIS OF A MAJOR GENE (cwp) WHOSE EVOLUTIONARY SILENCING CONTRIBUTED TO THE DOMESTICATION OF THE FLESHY TOMATO

PA-271 S. Cohen, N. Dai, L. Yeselson, S. Shen, J. Burger, U. Sahar, G. Tzuri, M. Lotan-Pomapan, M. Harel-Beja, V. Portnoy, N. Katzir, A.A. Schaffer, Israel IN SEARCH OF THE MAJOR GENE DETERMINING ORGANIC ACID ACCUMULATION IN C. MELO- CLONING OF THE PATHWAY AND MAPPING OF THE GENES

PA-272 V. Gaba, A. Gal-On, S. Singer, E. Kukurt, D. Leibman, L. Maslenin, Y.M. Shibolet, A. Rosner, Israel SMALL RNA PRODUCTION BY TRANSGENE GIVES VIRUS RESISTANCE DEPENDING ON THE DEGREE OF HOMOLOGY BETWEEN THE TRANSGENE AND THE CHALLENGE VIRUS

PA-273 A. Goldshmidt, J.P. Alvarez, Y. Eshed, Israel THE ROLE OF YABBY DERIVED SIGNALING IN PHYLLOTAXIS ESTABLISHMENT

PA-274 Y. Hacham, G. Schuster, L. Song, R. Amir, Israel EFFECT OF LYSINE ON METHIONINE METABOLISM

PA-275 Y. Halimi, M. Dasau, N. Levanon, E. Bachrach, N. Ohad, J. Hirsch, D.A. Chamovitz, Israel A STRUCTURE-FUNCTION STUDY OF THE COP9 SIGNALOSOME SUBUNIT 7

PA-276 R. Liberman, A. Bar-Akiva, L. Shahar, A. Nissim-Levi, H. Koltai, D. Weiss, V. Gaba, M. Reuveni, D. Evenor, M. Oren-Shamir, Israel PEROXIDASE INVOLVEMENT IN THE PROCESS OF ANTHOCYANIN DEGRADATION IN BRUNFELSIA FLOWERS

PA-277 C. Lifshitz, N. Shalit, S. Slotzky, Z. Tanami, Y. Elad, N. Dai, Israel HERITABILITY STUDIES AND DNA MARKERS FOR POWDERY MILDEW RESISTANCE IN STRAWBERRY FRAGARIA X ANANASSA DUCHESNE

PA-278 S. Malitsky, E. Blum, I. Venger, Y. Eshed, A. Aharoni, Israel THE PRIMARY - SECONDARY METABOLISM INTERFACE: METABOLIC CHANGES IN ARABIDOPSIS PLANTS OVEREXPRESSING FIVE RELATED TRANSCRIPTION FACTORS DETECTED BY GC-MS AND LC-MS TECHNOLOGIES

PA-279 T. Mandel, S. Mintz-Oron, A. Adato, M. Yativ, Israel, R. Jetter, Canada, I. Venger, I. Rogachev, A. Aharoni, Israel THE INS AND OUTS OF TOMATO FRUIT PEEL METABOLOME

PA-280 I. Matityahu, Y. Hacham, R. Amir, G. Schuster, Israel PLANTS EXPRESSING BACTERIAL AND MODIFIED ENZYMES OF THE METHIONINE BIOSYNTHESIS PATHWAY ACCUMULATE HIGH LEVELS OF METHIONINE AND THREONINE

PA-281 I. Mazor, M. Zaccai, Israel THE EFFECT OF VERNALIZATION AND LONG DAY ON L. CANDIDUM FLOWERING AND ON THE EXPRESSION OF LcLFY, A LEAFY HOMOLOGUE

PA-282 D. Michaeli, Israel, R.L. Fischer, USA, N. Ohad, Israel EMBRYO-SPECIFIC REGULATORY SEQUENCES ESSENTIAL FOR ARABIDOPSIS SEED DEVELOPMENT

PA-283 Withdrawn

PA-284 M. Moy, L. Yeselson, P. Marina, S. Shen, N. Dai, A.A. Schaffer, Israel COMPARISON OF THE COMPLETE GENOMIC INVERTASE SEQUENCES OF SUCROSE AND HEXOSE ACCUMULATING SPECIES OF THE LYCOPERSICON CLADE OF SOLANUM

66 Poster Session A – Dan (continued)

PA-285 I. Pankratov, N. Galpaz, D. Zamir, J. Hirschberg, Israel FRUIT CAROTENOID DEFICIENCY (fcd) MUTANTS IN TOMATO AS A TOOL TO STUDY REGULATION OF CAROTENOID BIOSINTHESYS

PA-286 M. Petreikov, S. Shen, Y. Yeselson, Israel, C.M. Bejar, A.A. Iglesias, J. Preiss, USA, A.A. Schaffer, Israel ACTIVITY AND REGULATORY PROPERTIES OF THE SUBUNITS OF TOMATO FRUIT AGPase AS HOMO- AND HETERO-TETRAMERS HETEROLOGOUSLY EXPRESSED IN E.coli

PA-287 O. Pisanty, E. Herzig, D. Meiri, A. Breiman, Israel THE ARABIDOPSIS THALIANA CO-CHAPERONE ROF1 AFFECTS TRANSCRIPTION PROFILING AND GERMINATION

PA-288 L. Poraty, O. Hazak, Israel, P. Zimmermann, W. Gruissem, Switzerland, S. Yalovsky, Israel A LINK BETWEEN DEVELOPMENTAL REGULATION OF ROP GTPase AND HORMONAL RESPONSES

PA-289 L. Golomb, M. Abu-Abied, E. Belausov, E. Sadot, Israel DIFFERENT SUBCELLULAR LOCALIZATIONS AND FUNCTIONS OF ARABIDOPSIS MYOSIN VIII

PA-290 A. Salman Minkov, T. Trebitsh, Israel THE ROLE OF ACC SYNTHASE GENES DURING WATERMELON FLOWER DEVELOPMENT

PA-291 A. Shammai, Y. Yeselson, S. Shen, A.A. Schaffer, Israel DIFFERENTIAL EXPRESSION ANALYSIS OF NEAR-ISOGENIC TOMATO LINES WITH DIFFERENT RATIOS OF FRUCTOSE TO GLUCOSE IN THE MATURE FRUIT

PA-292 I. Berezin, E. Brook, K. Mizrahi, M. Elazar, R. Gaash, M. Avramov, T. Mizrachy-Dagry, O. Shaul, Israel STUDYING THE PHYSIOLOGICAL FUNCTION OF THE ARABIDOPSIS METAL/PROTON EXCHANGER AtMHX IN PLANTS THAT ECTOPICALLY OVEREXPRESS THIS TRANSPORTER

PA-293 K. Shichrur, S. Yalovsky, Israel THE ARABIDOPSIS PRA FAMILY IS ESSENTIAL FOR PLANT DEVELOPMENT

PA-294 Withdrawn

PA-295 Withdrawn

PA-296 Withdrawn

PA-297 E. Yakir, D. Hillman, R.M. Green, Israel POST-TRANSCRIPTION AND POST-TRANSLATION REGULATION OF CCA1 AND LHY IN THE CIRCADIAN OSCILLATOR OF ARABIDOPSIS THALIANA

PA-298 E. Yaniv, L. Gelfarb, Israel, A. Distelfeld, USA, A.B. Korol, E. Nevo, T. Fahima, Israel WHEAT-RICE COLINEARITY AT THE Yr15 STRIPE RUST RESISTANCE GENE REGION IN TETRAPLOID WHEAT

PA-299 T. Yifhar, I. Pekker, J.P. Alvarez, M. Sabban, D. Peled, G. Shahar, Z. Amsellem, Y. Eshed, Israel SMALL RNAs FACILITATE POLARITY AND LAMINAR GROWTH OF TOMATO LEAVES

PA-300 I. Dangoor, A. Levitan, H. Peled-Zehavi, A. Danon, Israel CHARACTERIZATION OF A NOVEL PLASTIDIAL THIOREDOXIN-LIKE FAMILY IN ARABIDOPSIS

Secretory pathway

PA-301 D. Chetrit, M. Ehrlich, Israel Dab2 IS A CARGO SPECIFIC ENDOCYTIC ADAPTOR INVOLVED IN THE REGULATION OF CELL MATRIX INTERACTIONS

PA-302 L. Kliouchnikov, A. Parnis, N. Goldfeder, D. Cassel, Israel ROLE OF THE GTPase-ACTIVATING PROTEIN ArfGAP1-3 IN COPI MECHANISM

67 Poster Session A – Dan (continued)

PA-303 S. Levi, M. Rawet, L. Kliouchnikov, A. Parnis, D. Cassel, Israel TOPOLOGY OF AMPHIPATHIC MOTIFS MEDIATING GOLGI LOCALIZATION IN ArfGAP1 AND ITS SPLICE ISOFORMS

PA-304 O. Ravid, T. Nahari, N. Ben-Califa, E. Barzilay, D. Neumann, Israel A ROLE FOR THE ERYTHROPOIETIN RECEPTOR DOMAINS IN RECEPTOR MATURATION

PA-305 M. Rawet, A. Parnis, D. Cassel, Israel A NEW APPROACH FOR STUDYING THE ROLE OF CYTOSOLIC TRAFFICKING PROTEINS

PA-306 I. Shapira, K. Hirschberg, S. Bar-Nun, Israel DISCERNING BETWEEN RETENTION SIGNALS AND DEGRONS ACTING IN ERAD

PA-307 O. Weisshaus, V. Mann, J. Hirschberg, Israel PARACOCCUS MARCUSII – A CAROTENOGENIC BACTERIUM HARBORING A NOVEL SECRETION MECHANISM

Tissue engineering

PA-308 T. Kizhner, D. Ben David, Israel, T. Koheler, R. Mueller, Switzerland, E. Livne, S. Sruji, Israel CELL-SCAFFOLD TRANSPLANT OF HYDROGEL SEEDED WITH RAT BONE MARROW PROGENITORS FOR BONE REGENERATION

PA-309 N. Dahan, M. Machluf, Israel IMMUNOGENICITY OF ACELLULARIZED EXTRACELLULAR MATRIX FOR ARTERIAL TISSUE ENGINEERING

PA-310 T. Dvir, L. Oren, M. Shachar, Y. Granot, S. Cohen, Israel PULSATILE INTERSTITIAL FLUID FLOW PROMOTES ERK1/2 CASCADE LEADING TO CARDIAC TISSUE REGENERATION

PA-311 I. Freeman, S. Cohen, Israel SULFATION OF ALGINATE HYDROGELS ENABLES SPECIFIC BINDING AND SUSTAINED RELEASE OF HEPARIN-BINDING PEPTIDES

PA-312 D. Geblinger, C. Luxenburg, B. Geiger, L. Addadi, Israel OSTEOCLAST RESORPTION APPARATUS: STRUCTURE DYNAMICS AND ACTIVITY

PA-313 Y. Kaminer, A. Monsonego, S. Cohen, Israel BONE-MARROW STROMAL CELLS EXERT IMMUNOSUPPRESSIVE EFFECTS ON IMMUNE CELLS CO-CULTIVATED IN 3-D ALGINATE SCAFFOLDS

PA-314 O. Lesman, T. Elkayam, S. Cohen, Israel ALGINATE SCAFFOLD-CULTIVATED HUMAN HEPATOCYTE CELL LINE REVEALS SUPERIOR HEPATOCELLULAR FUNCTIONS COMPARED TO COLLAGEN SCAFFOLD-SEEDED CELLS

PA-315 E. Ruvinov, I. Freeman, R. Holbova, N. Landa, J. Leor, S. Cohen, Israel ALGINATE-BASED COTROLLED DELIVERY OF HGF AND IGF-1 IMPROVES SELF-REPAIR AND HEALING AFTER EXTENSIVE MYOCARDIAL INFARCTION

PA-316 A. Soroker, E. Mitrany, Israel PANCREAS TISSUE ENGINEERING FOR LONG TERM FUNCTION OF BETA CELLS

Virus molecular biology

PA-317 M. Abd El-Latif, A. Oppenheim, Israel DNA COMPACTION DURING IN VITRO ASSEMBLY OF SV40 CAPSIDS AROUND SUPERCOILED PLASMID DNA

PA-318 O. Ben-Nun-Shaul, H. Bronfeld, O. Schueler-Furman, A. Oppenheim, Israel THE ROLE OF A PENTAPEPTIDE HINGE OF THE SV40 MAJOR CAPSID PROTEIN IN ASSEMBLY AND CAPSID STABILITY

68 Poster Session A – Dan (continued)

PA-319 A. Brestovitsky, R. Sharf, T. Kleinberger, Israel STUDY OF THE INTERACTION BETWEEN THE ADENOVIRUS E4orf4 PROTEIN AND ACF1, A PROTEIN INVOLVED IN CHROMATIN REMODELING

PA-320 D. Cohen, Y. Shaul, Israel HOW VIRUSES ENSURE dNTP POOL IN NONDIVIDING CELLS: THE HBV MODEL

PA-321 D. Fradkin, S. Koby, A. Oppenheim, Israel MOLECULAR EVOLUTION OF VP1 FOR IMPROVED ASSEMBLY OF SV40-BASED VECTORS

PA-322 G. Gubi, L. Lobel, Israel ENGINEERING OF ANTI-INFLUENZA scFv, WHICH INHIBIT MULTI STRAIN INFLUENZA REPLICATION

PA-323 R. Hochman, E. Bar-Shira, A. Friedman, D. Leibman, T. Arazi, A. Gal-On, Israel DEVELOPMENT OF A PLANT VIRUS AS A UNIQUE PLATFORM FOR ORAL VACCINATION OF POULTRY

PA-324 S. Kler, A. Oppenheim, Israel PHOSPHORYLATION OF SV40 CAPSID PROTEINS IS REQUIRED FOR DNA PACKAGING

PA-325 S. Krispel, D. Lazarus, M. Pasmanik-Chor, J. Pitcovski, Israel ATTENUATION OF VERY VIRULENT INFECTIOUS BURSAL DISEASE VIRUS AND COMPARISON OF FULL SEQUENCES OF VIRULENT AND ATTENUATED STRAINE

PA-326 A. Levin, J. Rosenbluh, Z. Hayouka, A. Friedler, A. Loyter, Israel REGULATION OF THE HIV-1 INTEGRASE ACTIVITY BY THE VIRAL REV PROTEIN: THE EFFECT OF CELL PERMEABLE PEPTIDES DERIVED FROM THE INTEGRASE AND Rev PROTEINS

PA-327 R. Oren Benaroya, R. Azar, D. Katz, E. Mendelson, M. Mandelboim, Israel NOVEL APPROACHES FOR TREATMENT OF AVIAN INFLUENZA INFECTION

PA-328 N. Zauberman, Y. Mutsafi, E. Klein, E. Shimoni, A. Minsky, Israel TWO DISTINCT PORTALS IN THE GIANT ACANTHAMOEBA POLYPHAGA MIMIVIRUS

PA-329 A. Oppenheim, A. Gordon-Shaag, S. Mukherjee, O. Ben-Nun-Shaul, M. Abd El-Latif, H. Bronfeld, S. Kler, Israel SV40 ASSEMBLY IN VIVO AND IN VITRO

69 20:00 – 22:30 Poster Session A Zone 3, Royal Beach

Drug development

PA-330 M. Arbel, B. Solomon, Israel A NOVEL APPROACH FOR TREATMENT OF ALZHEIMER`S DISEASE: ANTIBODIES AGAINST BETA-SECRETASE CLEAVAGE SITE OF APP

PA-331 Y. Nechemia-Arbely, D. Barkan, G. Pizov, A. Shriki, Israel, S. Rose-John, Germany, E. Galun, J.H. Axelrod, Israel IL-6/IL-6R AXIS PLAYS A CRITICAL ROLE IN ACUTE KIDNEY INJURY

PA-332 T. Bronshtein, S. Pollack, M. Machluf, Israel CCR5-CONJUGATED STEALTH-LIPOSOMES. A NEW DRUG DELIVERY SYSTEM TO HIV RESERVOIR CELLS AND FREE VIRION ENTRAPMENT

PA-333 B. Brumshtein, T.H. Futerman, I. Silman, J.L. Sussman, Israel A 3D PERSPECTIVE ON GAUCHER DISEASE

PA-334 E. Chauser-Volfson, Y. Gutterman, Israel TECHNOLOGIES TO INCREASE THE CONTENT OF SECONDARY PHENOLIC METABOLITES (SPhMs) IN ALOE SPECIES

PA-335 M. Cherniavsky, T. Baasov, Israel HIGH THROUGHPUT SCREENING OF SYNTHETIC LIBRARIES FOR DISCOVERY OF POTENTIAL DRUG CANDIDATES FOR TREATMENT OF HUMAN GENETIC DISEASES

PA-336 T. Cohen, M. Pevsner-Fischer, N. Cohen, I.R. Cohen, Y. Shai, Israel CHARACTERIZATION OF THE INTERACTING DOMAIN OF THE HIV-1 FUSION PEPTIDE WITH THE TRANSMEMBRANE DOMAIN OF THE T-CELL RECEPTOR

PA-337 H. Dimant, N. Sharon, B. Solomon, Israel MODULATION OF INTRACELLULAR AGGREGATES THROUGH FILAMENTOUS PHAGES IN A CELLULAR MODEL OF PD

PA-338 I. Rakover, K. Elsner, B. Solomon, Israel INTRANASAL DELIVERY OF FILAMENTOUS PHAGE DISPLAYING MYELIN IMMUNODOMINANT EPITOPES TOWARD MULTIPLE SCLEROSIS TREATMENT

PA-339 Y. Friedmann, A. Shriki, E.R. Bennett, S. Golos, R. Diskin, I. Marbach, E. Bengal, D. Engelberg, Israel JX401, A P38ALPHA INHIBITOR CONTAINING A 4-BENZYLPIPERIDINE MOTIF, IDENTIFIED VIA A NOVEL SCREENING SYSTEM IN YEAST

PA-340 A. Frydman-Marom, M. Recther, I. Shefler, Y. Bram, D.E. Shalev, E. Gazit, Israel A NOVEL BETA-BREAKER PEPTIDE EMERGES AS POTENTIAL AMYLOID-BETA FIBRILS ARREST

PA-341 S. Gilead, E. Gazit, Israel UNCOVERING NATURE’S ROUTE FOR AMYLOID PREVENTION: MOLECULAR MAPPING OF THE RECOGNITION INTERFACE BETWEEN THE ISLET AMYLOID POLYPEPTIDE AND INSULIN

PA-342 Z. Hayouka, A. Levin, A. Loyter, A. Friedler, Israel INHIBITING HIV-1 INTEGRASE BY SHIFTING ITS OLIGOMERIZATION EQUILIBRIUM

PA-343 A. Lampel, A. Marom-Frydman, E. Gazit, Israel ENDOMORPHIN-1 AND ENDOMORPHIN-2 AS A PROMISING ENDOGENOUS AMYLOID-BETA INHIBITORS

PA-344 G. Lerman, D. Avni, Y. Sidi, Israel THE USE OF GENE SILENCING RNAI TECHNOLOGY FOR ANTI APOPTOTIC GENES AS A POSSIBLE TREATMENT FOR PSORIASIS

PA-345 M. Levy, E. Gazit, D. Segal, Israel EXPLORING THE INFLUENCE OF CHEMICAL CHAPERONES ON LIVING ORGANISM USING FLIES MUTATED IN SERPIN NECROTIC GENE

70 Poster Session A – Royal Beach (continued)

PA-346 Y. Linde, S. Hess, O. Ovadia, T. Lapidot, I. Winkler, A. Faier, D. Yarden, E. Safrai, D.E. Shalev, Israel, C. Haskell-Luevano, USA, A. Hoffman, C. Gilon, Israel THE INTESTINAL AND BBB PERMEABILITY OF THE ORALLY ACTIVE MC4 AGONIST BL-3020-1 IS SEQUENCE AND CONFORMATIONAL DEPENDENT

PA-347 Withdrawn

PA-348 I. Maniv, L. Veenman, S. Leschiner, I. Spanier, I. Marek, A. Shterenberg, E. Hadad, M. Gavish, Israel THE QUINAZOLINE DERIVATIVE 9a AS A NEUROPROTECTIVE AGENT

PA-349 M. Mendelson, A. Porgador, A. David, Israel CHARACTERIZING THE CARBOHYDRATE STRUCTURE OF NKp46 RECEPTOR FOR DESIGNING GLYCOPOLYMERS WITH INHIBITORY ACTIVITIES TOWARDS INFLUENZA VIRUS INFECTION

PA-350 I. Nudelman, Israel, S.R. Akabayov, USA, J.H. Chill, R. Levy, N. Kessler, J. Anglister, Israel NMR STRUCTURAL STUDIES OF THE HUMAN INTERFERON alpha2 COMPLEX WITH THE HUMAN TYPE I INTERFERON RECEPTOR

PA-351 A. Ochaion, S. Cohen, F. Barer, R. Patoka, S. Bar Yehuda, Israel, L. Del Valle, G. Perez Liz, USA, J. Ophir, R. Musberg-Galili, T. Reitblat, H. Amital, P. Fishman, Israel A3 ADENOSINE RECEPTOR IS OVER-EXPRESSED IN AUTO-IMMUNE INFLAMMATORY DISEASES: A NOVEL TARGET TO COMBAT INFLAMMATION

PA-352 O. Sabag, H. Lorberboum-Galski, Israel USING CHIMERIC PROTEIN TO TARGET AND TREAT BACTERIAL INFECTIONS

PA-353 R. Scherzer, A. Frydman-Marom, E. Gazit, Israel NOVEL QUINONE BASED MOLECULES AS INHIBITORS OF Abeta OLIGOMER FORMATION IN ALZHEIMER'S DISEASE

PA-354 N. Shani, Z. Shani, O. Shoseyov, D. Shoseyov, Israel INHIBITION OF ALLERGIC ASTHMA IN AN ANIMAL MODEL BY OXIDIZED CELLULOSE MICROPARTICLES

PA-355 A. Shusterovitch, S. Gilead, E. Gazit, Israel THE ISLET AMYLOID POLYPEPTIDE CRYSTALLIZATION

PA-356 A. Vallon-Eberhard, A. Makovitzki, S. Jung, Y. Shai, Israel EFFICIENT CLEARANCE OF ASPERGILLUS FUMIGATUS BY ULTRASHORT ANTI-MICROBIAL LIPOPEPTIDES IN MURINE LUNGS

PA-357 Withdrawn

PA-358 H. Yehuda, S. Khatib, I. Sussan, R. Musa, J. Vaya, S. Tamir, Israel 4-METHYLTHIOBUTYLISOTHIOCYANATE (MTBI) AS A POTENTIAL ANTI-PSORIATIC AGENT

Emerging diseases

PA-359 H. Bin, L. Shulman, U. Shalom, I. Groto, N. Davidovitch, R. Balicer, T. Meir, L. Weiss, K. Shilon, Israel, M. Niedrig, Germany, L. Nicolleti, Italy, T. Kato, Israel, A. Papa, Greece, H. Habib, G. Rahav, E. Mendelson, Israel SANDFLY VIRUSES ARE STILL ENDEMIC IN ISRAEL

PA-360 V. Indenbaum, H. Bin, D. Makarovsky, M. Albeck, B. Sredni, E. Mendelson, Israel AS101 ANTIVIRAL EFFECT ON WEST NILE VIRUS IN VITRO AND IN VIVO

PA-361 Y.Y. Broza, Y. Danin-Poleg, L. Lerner, Y. Kashi, Israel SSR BASED TYPING AND EPIDEMIOLOGICAL STUDY OF ENVIRONMENTAL VIBRIO VULNIFICUS

PA-362 A. Sobarzo, Israel, J.T. Paweska, South Africa, S. Herrmann, T. Amir, R.S. Marks, L. Lobel, Israel OPTICAL FIBER IMMUNOSENSOR FOR THE DETECTION OF IgG ANTIBODY TO RIFT VALLEY FEVER VIRUS

71 Poster Session A – Royal Beach (continued)

Gene and cell therapy

PA-363 O. Atar, D. Alaluf, K.B. Avraham, Israel PREVENTION OF HAIR CELL DEATH IN TRANSCRIPTION FACTORS Pou4f3 AND Gfi1 KNOCKOUT MICE USING ANTI-APOPTOTIC FACTORS

PA-364 V. Aviv, I. Meivar-levy, S. Ferber, Israel THE ROLE OF GLP-1 IN PROMOTING Pdx-1 INDUCED LIVER TO PANCREAS TRANSDIFFERENTIATION

PA-365 Y. Bar, H.A. Russ, S. Knoller, S. Efrat, Israel HES1 IS INVOLVED IN ADAPTATION OF ADULT HUMAN BETA CELLS TO PROLIFERATION IN VITRO

PA-366 D. Berneman, I. Meivar-levy, S. Ferber, Israel THE ROLE OF Pax4 AND MafA IN THE TRANSDIFFERENTIATION PROCESS OF LIVER CELLS TOWARDS PANCREATIC BETA CELLS

PA-367 V. Butin-Israeli, D. Uzi, M. Abd El-Latif, G. Pizov, A. Eden, Y.S. Haviv, A. Oppenheim, Israel SV40 EMPTY CAPSIDS PROTECT FROM ORGAN FAILURE BY ELICITING CELLULAR SIGNALS AND HOST DEFENCE

PA-368 Y. de Rooy, K. Molakandov, I. Meivar-Levy, S. Ferber, Israel THE ROLE OF THE GROWTH FACTOR- ACTIVIN A ON PDX-1 INDUCED LIVER TO PANCREAS TRANSDIFFERENTIATION PROCESS

PA-369 O. Erster, M. Eisenstein, M. Liscovitch, Israel LIGAND INTERACTION SCAN: ENGINEERING A LIGAND-MODULATED PROTEIN

PA-370 M. Grafi-Cohen, G. Weisinger, R. Limor, E. Izkhakov, Z. Kraiem, N. Stern, Israel DEVELOPMENT OF THYROID CANCER-SPECIFIC GENE THERAPY VECTOR(S)

PA-371 R. Condiotti, A. Grinshpun, S. Peretz, Israel, J. Chou, USA, E. Galun, Israel CORRECTION OF GLYCOGEN STORAGE DISEASE 1a IN A MURINE MODEL USING A NON-PRIMATE LENTIVIRAL VECTOR

PA-372 Y. Izhar-Prato, O. Karnieli, S. Bulvik, S. Efrat, Israel DIFFERENTIATION OF MESENCHYMAL STEM CELLS FROM ADULT HUMAN BONE MARROW INTO PANCRETIC ENDOCRINE CELLS INDUCED BY NEUROGENIN3 AND NEUROD1

PA-373 M. Mauda-Havakuk, O. Nakar, I. Meivar-Levy, A. Liran, S. Ferber, Israel CELL-REPLACMENT THERAPY FOR DIABETES; THE USE OF HUMAN SKIN CELLS AS A SOURCE OF AUTOLOGOUS INSULIN PRODUCING CELLS

PA-374 K. Molakandov, Israel, D.T. Curiel, USA, S. Ferber, Israel Pdx1-vp16: A POTENET AGENT FOR LIVER TO PANCREAS TRANSDIFFERENTIATION

PA-375 I. Rachmut, S. Gefen-Halevi, I. Meivar-Levy, S. Ferber, Israel THE ROLE OF HGF AND Nkx6.1 IN Pdx1 INDUCED LIVER TO PANCREAS TRANSDIFFERNTIATION

PA-376 H.A. Russ, Y. Bar, Israel, P. Ravassard, France, S. Efrat, Israel PROLIFERATION OF DEDIFFERENTIATED ADULT HUMAN PANCREATIC BETA CELLS IN VITRO REVEALED BY CELL-LINEAGE TRACING

PA-377 D. Uzi, M. Abd El-Latif, V. Butin-Israeli, G. Pizov, Y. Haviv, A. Oppenheim, Israel ATTENUATION OF ACUTE KIDNEY INJURY BY SV40 CAPSID PROTETINS

PA-378 J. Zazoun, D. Mevorach, Israel APOPTOTIC CELL THERAPY IN GRAFT-VERSUS-HOST DISEASE

72 Poster Session A – Royal Beach (continued)

Hormones: behaviors and diseases

PA-379 R. Ashwal, R. Rosenblum, E. Yissachar, M. Hanochi, L. Granot, A. Karasik, R. Hemi, H. Kanety, Israel IDENTIFICATION AND CHARACTERIZATION OF NOVEL ADIPONECTIN RECEPTOR 1 ISOFORMS

PA-380 L. Hershkovitz, Israel, F. Beuschlein, Germany, M. Krup, Y. Weinstein, Israel ADRENAL 20ALPHA HYDROXYSTEROID DEHYDROGENASE (20HSD) EXPRESSION IS RESTRICTED TO THE X-ZONE

PA-381 A. Khalaileh, Y. Dor, Israel DETERMINANTS OF PANCREATIC BETA CELL PROLIFERATION AND MASS: A PARABIOSIS APPROACH

PA-382 N. Litichever, E. Gershon, T.D. Schirman-Hildesheim, N. Ben-Aroya, N. Dekel, Y. Koch, Israel HORMONAL REGULATION OF LUTENIZING HORMONE(LH)-BETA AND GONADOTROPIN RELEASING HORMONE (GnRH) mRNA EXPRESSION IN CULTURED GRANULOSA CELLS

PA-383 T. Meir, R. Levi, T. Naveh-Many, J. Silver, Israel PARATHYROID-SPECIFIC KNOCK-OUT OF THE VITAMIN D RECEPTOR DEMONSTRATES THE ROLE OF VITAMIN D IN PARATHYROID PHYSIOLOGY

PA-384 S. Motola, M. Popliker, A. Tsafriri, Israel ARE STEROIDS DISPENSABLE FOR LH/HCG TRIGGERED RESUMPTION OF MEIOSIS IN MAMMALS

PA-385 M. Stolovich-Rain, Y. Dor, Israel FETAL ORIGINS OF ADULT METABOLIC DISEASE: THE ROLE OF PANCREATIC BETA CELLS

PA-386 D. Swartzberg, B. Kirshner, D. Rav-David, Y. Elad, D. Granot, Israel BOTYRTIS CINEREA INDUCE SENESCENCE AND IS INHIBITED BY AUTOREGULATED PRODUCTION OF IPT GENE

PA-387 A. Veprik, M. Khanin, K. Hirsch, M. Danilenko, J. Levy, Y. Sharoni, Israel EATING SALAD, IS IT GOOD FOR YOUR BONES? PLANT-DERIVED MICRONUTRIENTS INHIBIT ESTROGEN SIGNALING IN BREAST CANCER BUT NOT IN BONE CELLS

PA-388 D. Weinstein, M. Simon, Z. Laron, H. Werner, Israel LONG-ACTING INSULIN ANALOGUES HAVE MITOGENIC AND ANTIAPOPTOTIC ACTIVITIES

PA-389 E. Yissachar, R. Ashwal, U. Nir, A. Karasik, R. Hemi, H. Kanety, Israel IDENTIFICATION AND CHARACTERIZATION OF NOVEL SPLICE VARIANTS OF THE ADIPONECTIN RECEPTOR-2 (AdipoR2)

Protein degradation and quality control

PA-390 A. Akerman, R. Rosen, A. Sacher, D. Biran, Israel PHOSPHORYLATED ACIDIC PROTEINS IN ESCHERICHIA COLI

PA-391 A. Atir-Lande, T. Gildor, D. Kornitzer, Israel ROLE OF THE SCF UBIQUITIN LIGASE IN CANDIDA ALBICANS MORPHOGENESIS

PA-392 E. Avezov, G.Z. Lederkremer, Israel COMPARTMENTALIZED ER MANNOSIDASE I IS REQUIRED FOR EXTENSIVE N-GLYCAN TRIMMING WHICH LEADS TO ER-ASSOCIATED DEGRADATION OF GLYCOPROTEINS

PA-393 A. Bahat, Z. Granot, S. Eimerl, O. Kobiler, Israel, B. Lu, USA, A.B. Oppenheim, Israel, C.K. Suzuki, USA, J. Orly, Israel TURNOVER OF StAR PROTEIN: ROLES FOR THE PROTEASOME AND MITOCHONDRIAL PROTEASES

73 Poster Session A – Royal Beach (continued)

PA-394 N. Alumot, A. Cohen, S. Bar-Nun, Israel polyQ DISEASES IN YEAST MODEL: AGGREGATION, TOXICITY AND QUALITY CONTROL IN GROWING OR NON-DIVIDING YEAST

PA-395 A. Darom, L. Broday, Israel RNF121 – ANOTHER PLAYER IN THE ERAD MACHINERY?

PA-396 E. Erez, E. Bibi, Israel STUDYING A POSSIBLE QUALITY CONTROL ROLE FOR RHOMBOID, AN INTRA-MEMBRANE SERINE PROTEASE

PA-397 B. Groisman, E. Ron, G.Z. Lederkremer, Israel MANNOSE TRIMMING AND ERAD SUBSTRATE LOCALIZATION POSSIBLE INVOLVEMENT OF TRIMMING IN SUBSTRATE RELEASE FROM EDEM1

PA-398 M. Ish-Shalom, L. Naveh, Z. Adam, Israel THE EFFECT OF MODULATED LEVELS OF THE REGULATORY SUBUNIT OF Clp PROTEASE ON THE EXPRESSION OF FOREIGN PROTEINS IN TOBACCO CHLOROPLASTS

PA-399 L. Broday, R. Kaminsky, Israel, C. Denison, S.P. Gygi, USA SUMOYLATION OF CYTOPLASMIC INTERMEDIATE FILAMENT PROTEINS IN C. ELEGANS ARE REQUIRED FOR FILAMENT ASSEMBLY

PA-400 C. Katz, E. Gur, A. Parket, E. Ron, Israel ALL THREE J-DOMAIN PROTEINS OF THE ESCHERICHIA COLI DnaK CHAPERONE MACHINERY ARE DNA BINDING PROTEINS

PA-401 T. Listovsky, D. Zilberstein, Israel CHARACTERIZATION OF A Cdc20 HOMOLOGUE IN LEISHMANIA DONOVANI AND ITS ROLE DURING CELL CYCLE

PA-402 E. Milner, E. Barnea, E. Kario, A. Navon, A. Admon, Israel CONNECTING THE PROTEOME, THE DEGRADOME AND THE MHC-PEPTIDOME OF HUMAN CANCER CELLS

PA-403 I. Mizrahi, D. Biran, E. Ron, Israel REQUIREMENT FOR THE ACETYL PHOSPHATE PATHWAY FOR ATP-DEPENDENT PROTEOLYSIS IN ESCHERICHIA COLI

PA-404 B. Bercovich, T. Noy, A. Ciechanover, Israel THE SACCHAROMYCES CEREVISIAE AS A MODEL SYSTEM FOR THE IDENTIFICATION OF THE E3 UBIQUITIN LIGASE, WHICH FACILITATES THE FORMATION OF n-TERMINAL UBIQUITIN CONJUGATED CHAIN

PA-405 A. Ofir, A. Atir-Lande, D. Kornitzer, Israel CYCLIN-DEPENDENT KINASE REGULATION BY THE C. ALBICANS CDK INHIBITOR Sol1

PA-406 O. Ohayon, E. Rabinovich, S. Bar-Nun, Israel THE ROLE OF Ssz1 IN THE ENDOPLASMIC RETICULUM-ASSOCIATED DEGRADATION

PA-407 Z. Porat, G. Landau, Z. Bercovich, D. Krutauz, M.H. Glickman, C. Kahana, Israel YEAST ANTIZYME MEDIATES DEGRADATION OF YEAST ORNITHINE DECARBOXYLASE BY YEAST BUT NOT BY MAMMALIAN PROTEASOME

PA-408 A. Rasouly, Y. Shenhar, E. Ron, Israel THERMOREGULATION OF ESCHERICHIA COLI hchA TRANSCRIPT STABILITY

PA-409 R. Rimon Knopf, A. Feder, Z. Adam, Israel CHARACTERIZATION OF RHOMBOID PROTEASES IN ARABIDOPSIS THALIANA CHLOROPLASTS

PA-410 E. Ron, E. Avezov, G.Z. Lederkremer, Israel THE COMBINED ACTIVITY OF ER MANNOSIDASE I AND EDEM1 IS REQUIRED FOR ER- ASSOCIATED DEGRADATION

74 Poster Session A – Royal Beach (continued)

PA-411 R. Rosenzweig-Geideman, Israel, P.A. Osmulski, M. Gaczynska, Israel, M.H. Glickman, Israel A MASON'S APPROACH TO THE 19S PROTEASOME REGULATOR

PA-412 N. Sela, A. Lande-Atir, D. Kornitzer, Israel ROLE OF CAND1 AND NEDDYLATION IN SCF UBIQUITIN LIGASE ACTIVITY

PA-413 Y. Shenhar, A. Rasouly, E. Ron, Israel REGULATION OF THE HEAT SHOCK RESPONSE BY TEMPERATURE-DEPENDENT CHANGES IN TRANSCRIPT STABILITY

PA-414 M. Shenkman, G.Z. Lederkremer, Israel ER STRESS INDUCES ALTERNATIVE NON-PROTEASOMAL DEGRADATION OF ER PROTEINS BUT NOT OF CYTOSOLIC ONES

PA-415 Z. Snapir, A. Keren-Paz, Z. Bercovich, C. Kahana, Israel ODC PARALOG: FROM MODE OF DEGRADATION TO EFFECTS ON POLYAMINE HOMEOSTASIS AND PROLIFERATION

PA-416 P. Tsvetkov, N. Reuven, Y. Shaul, Israel WHY AND HOW p53 UNDERGOES UBIQUITIN INDEPENDENT PROTEASOMAL DEGRADATION

PA-417 I. Yosef, E. Bibi, Israel STUDYING REGULATORY ASPECTS OF THE SRP PATHWAY IN E. COLI: QUALITY CONTROL ACTIVITY OF Ffh

PA-418 D. Zaaroor, R. Ben-Saadon, A. Ciechanover, Israel THE POLYCOMB PROTEIN Ring1B GENERATES SELF ATYPICAL MIXED UBIQUITIN CHAINS REQUIRED FOR ITS IN VITRO HISTONE H2A LIGASE ACTIVITY

PA-419 I. Ziv, O. Kleifeld, M.H. Glickman, Israel THE LINKAGE PROFILE OF THE UBIQUITINOME

RNA world/processing

PA-420 L. Agranat, O. Raitskin, J. Sperling, R. Sperling, Israel THE EDITING ENZYME ADAR1 AND THE mRNA SURVEILLANCE PROTEIN hUpf 1 INTERACT IN THE NUCLEUS

PA-421 A. Aizer, Y. Shav-Tal, Israel THE DYNAMICS OF MAMMALIAN P BODY TRANSPORT, ASSEMBLY AND DISASSEMBLY IN VIVO

PA-422 Z.S. Barbash, M. Safran, Israel, E.Y. Levanon, USA, Y. Cohen, A.J. Simon, N. Amariglio, I. Goldstein, G. Rechavi, Israel THE ROLE OF A-TO-I RNA EDITING IN CHRONIC MYELOID LEUKEMIA

PA-423 A. Bezawork, I. Keren, M. Kolton, F. Shaya, O. Ostersetzer, Israel THE ROLES OF NUCLEAR-ENCODED MATURASES IN PLANT ORGANELLAR GROUP II INTRON RNA SPLICING

PA-424 E. Bronshtein, G. Schuster, Israel POST TRANSCRIPTIONAL ADDITION OF HETEROPOLYMERIC TAILS TO RNA IN CYTOPLASM OF HUMAN CELLS

PA-425 S. Cohen-Chalamish, A. Hasson, D. Weinberg, L.S. Namer, Y. Banai, F. Osman, R. Kaempfer, Israel DYNAMIC REFOLDING OF INTERFERON-GAMMA mRNA ITS DUAL FUNCTION AS TRANSLATION TEMPLATE AND ACTIVATOR OF PKR

PA-426 A. Dahan, Y. Brody, M. Angenitski, Y. Shav-Tal, Y. Sperling, R. Sperling, Israel ISOLATION OF SUPRASPLICEOSOMES ASSEMBLED ON A SPECIFIC TRANSCRIPT IN VIVO

PA-427 E. Eliyahu, D. Melamed, L. Pnueli, Y. Arava, Israel INVOLVEMENT OF THE TOM COMPLEX IN mRNA LOCALIZATION TO THE MITOCHONDRIA'S MEMBRANE

75 Poster Session A – Royal Beach (continued)

PA-428 S.K. Gupta, M.Z. Stern, M. Salmon-Divon, O. Barda, T. Hacham, S. Levi, S. Michaeli, Israel TWO POLYPYRIMIDINE-LIKE BINDING PROTEIN (PTB) IN TRYPANOSOMA BRUCEI: THEIR ROLE IN MESSENGER RNA STABILITY AND SPLICING

PA-429 L. Haim, G. Zipor, J.E. Gearst, Israel A GENOMIC-TAGGING STRATEGY TO VISUALIZE ENDOGENOUS mRNA IN LIVING YEAST

PA-430 A. Hury, Y. Ziporen, S. Barth, R. Katz, S. Michaeli, Israel IDENTIFICATION AND CHARACTERIZATION OF SMALL NUCLEOLAR RNAS AND PROTEINS INVOLVED IN TRYPANOSOME SPECIFIC rRNA PROCESSING

PA-431 L. Ilan, F. Osman, S. Cohen-Chalamish, G. Haviv, M. Eitan, Y. Banai, R. Kaempfer, Israel THE RNA ACTIVATOR OF PKR ESSENTIAL FOR SPLICING OF HUMAN BETA-GLOBIN mRNA

PA-432 E. Kamhi, Y. Hacham, R. Sperling, J. Sperling, Israel A POTENTIAL ROLE FOR INITIATOR-tRNA IN PRE-mRNA SPLICING REGULATION

PA-433 I. Keren, L. Klipcan, A. Bezawork, O. Ostersetzer, Israel CRM: A NOVEL RNA BINDING DOMAIN WITH SIMILAR ARCHITECTURE AND BINDING PROPERTIES TO THE RRM MOTIF

PA-434 R. Khosravi, Y. Shiloh, Israel FUNCTIONAL ANALYSIS OF A NOVEL PLAYER IN THE ATM-MEDIATED DNA DAMAGE RESPONSE WITH PROPERTIES OF AN RNA-PROCESSING ENZYME

PA-435 S. Larom, G. Schuster, Israel UNRAVELING THE IDENTITY OF THE RNA POLYADENYLATION ENZYMES IN THE CHLOROPLAST OF DIFFERENT PLANTS

PA-436 I. Lebenthal, R. Unger, Israel LINGUISTIC CHARACTERIZATION OF NON-CODING RNA

PA-437 L. Linde, Israel, S. Boelz, Germany, M. Nissim-Rafinia, Y.S. Oren, M. Wilschanski, Y. Yaakov, Israel, G. Neu-Yilik, A.E. Kulozik, Israel/Germany, E. Kerem, B. Kerem, Israel NMD MECHANISM AS A GENETIC MODIFIER OF THE RESPONSE TO READTHROUGH TREATMENT

PA-438 V. Liveanu, G. Schuster, Israel WHO DEGRADES THE MITOCHONDRIAL RNA?

PA-439 L.S. Namer, F. Osman, S. Cohen-Chalamish, R. Jung, A. Biran, Y. Banai, R. Kaempfer, Israel STRUCTURE OF THE RNA ACTIVATOR OF PKR THAT REGULATES SPLICING OF HUMAN TUMOR NECROSIS FACTOR mRNA

PA-440 Y. Nevo, G. Saper, J. Sperling, R. Sperling, Israel SUPPRESSION OF SPLICING IN THE NEMATODE CAENORHABDITIS ELEGANS

PA-441 S. Osenberg, Israel INITIAL CHARACTERIZATION OF THE A-TO-I RNA EDITING PHENOMENON DURING hESCs DIFFERENTIATION

PA-442 N. Paz, Israel, E.Y. Levanon, Israel/USA, N. Amariglio, Israel, A.B. Heimberger, USA, Z. Ram, S. Constantini, Z.S. Barbash, K. Adamsky, M. Safran, A. Hirschberg, M. Krupsky, I. Ben-Dov, Israel, S. Cazacu, T. Mikkelsen, C. Brodie, USA, E. Eisenberg, G. Rechavi, Israel ALTERED ADENOSINE TO INOSINE RNA EDITING IN HUMAN CANCER

PA-443 V. Portnoy, G. Schuster, Israel THE INTERPLAY BETWEEN RNA POLYADENYLATION AND DEGRADATION IN THE THREE DOMAINS OF LIFE

PA-444 O. Raitskin, N. Sznajder, J. Sperling, R. Sperling, Israel ALTERNATIVE SPLICING WITHIN THE SUPRASPLICEOSOME

76 Poster Session A – Royal Beach (continued)

PA-445 L. Klipcan, N. Kessler, I. Levin, I. Finarov, Israel, N. Moor, Russia, M. Safro, Israel FIRST CRYSTAL STRUCTURE OF THE CLASS II MONOMERIC HUMAN MITOCHONDRIAL PheRS AT 2.2A RESOLUTION

PA-446 A. Schein, G. Schuster, Israel EUKARYOTIC RIBONUCLEASE E

PA-447 H. Shaked, G. Arvatz, L. Rozenboim, S. Michaeli, Israel SLD – A QUALITY CONTROL MECHANISM TO DISCARD DEFECTIVE SPLICED LEADER RNA IN TRYPANOSOMA BRUCEI

PA-448 S. Shazman, Y. Mandel-Gutfreund, Israel CLASSIFYING RNA-BINDING PROTEINS BASED ON ELECTROSTATIC PROPERTIES

PA-449 M. Safran, O. Sherf, N. Paz, Z.S. Barbash, S. Ausenberg, D. Dominissini, G. Hout-Siloni, Y. Cohen, N. Amariglio, G. Rechavi, Israel MASS-SPECTROMETRY BASED HIGH THROUGHPUT QUANTITATIVE ANALYSIS OF A-TO-I RNA EDITING

PA-450 B. Slobodin, J.E. Gerst, Israel A NEW STRATEGY FOR ISOLATING mRNA BINDING PROTEINS

PA-451 S. Slomovic, G. Schuster, Israel STABLE PNPASE RNAI SILENCING; ITS EFFECT ON THE PROCESSING AND ADENYLATION OF HUMAN MITOCHONDRIAL RNA

PA-452 I.D. Tkacz, S. Cohen, A. Hury, M. Salmon-Divon, S. Michaeli, Israel SL RNA BIOGENESIS AND THE UNIQUE SETS OF HEPTAMERIC Sm/Lsm CORE PROTEINS COMPLEXES IN TRYPANOSOMA BRUCEI

PA-453 A. Loya, L. Pnueli, Y. Yosefzon, Y. Wexler, M. Ziv-Ukelson, Y. Arava, Israel THE 3' UTR MEDIATES THE CELLULAR LOCALIZATION OF AN mRNA ENCODING A SHORT PLASMA MEMBRANE PROTEIN

PA-454 M. Zhou, S. Marom, C. Gilon, J. Sperling, R. Sperling, Israel INHIBITION OF pre-mRNA SPLICING BY PEPTIDE ANALOGS OF SPLICING FACTORS

PA-455 G. Zipor, L. Haim, J. Gerst, Israel LOCALIZATION OF mRNAs ENCODING PEROXISOMAL PROTEINS IN YEAST

Translation

PA-456 H. Amit, A. Maissel, M. Shapira, E. Livneh, Israel TRANSLATIONAL CONTROL OF PROTEIN KINASE C'ETA' BY TWO UPSTREAM OPEN READING FRAMES (uORFs)

PA-457 Z. Bloom, O. Mizrachi-Man, O. Dahan, Y. Pilpel, Israel DECIPHERING THE EFFECT OF CODON USAGE ON TRANSLATION EFFICIENCY AND PROTEIN LEVELS IN S.CEREVISIAE

PA-458 O. Cheshin, O. Meyuhas, Israel AMP KINASE AND THE TUBEROSCLEROSIS COMPLEX MEDIATE ANOXIA-DEPNDENT TRANSLATIONAL REPRESSION OF TOP mRNAs

PA-459 N. Eldad, L. Pnueli, Y. Arava, Israel A NOVEL INTERACTION BETWEEN 3' UTR FRAGMENTS AND THEIR ORF AS SUGGESTED BY THEIR SIMILAR SEDIMENTATION IN SUCROSE GRADIENT

PA-460 S. Hen, O. Elroy-Stein, Israel A SEARCH FOR FACTOR THAT MEDIATE THE IRES ACTIVITY OF CrTMV

PA-461 R. Ladovsky Prizant, I. Barash, Israel AMINO ACIDS CONTROL mTOR SIGNALING PATHWAY IN MAMMARY EPITHELIAL CELLS

77 Poster Session A – Royal Beach (continued)

PA-462 I. Lazar, Israel THE ROLE OF LIVIN IN ONCOGENESIS REVEALS A NOVEL MODE OF GENE REGULATION

PA-463 L. Marom, O. Elroy-Stein, Israel CROSS KINGDOM CONSERVATION OF IRES FUNCTION:INVOLVEMENT OF POLY(A)-BINDING PROTEIN?

PA-464 M. Prizant, A. Arditi-Duvdevany, I. Ben-Dror, P. Polak, Y. Shav-Tal, L. Vardimon, Israel THE CYTOSKELETAL NETWORK CONTROLS THE TRANSLATION OF THE c-JUN PROTEIN IN A UTR-DEPENDENT MANNER

PA-465 H. Saul, O. David-Assael, V. Saul-Tcherkas, E. Brook, I. Berezin, O. Shaul, Israel POST-TRANSCRIPTIONAL REGULATION OF THE ARABIDOPSIS METAL TRANSPORTER AtMHX

PA-466 G. Sivan, Israel, N. Kedersha, USA, O. Elroy-Stein, Israel TRANSLATIONAL REGULATION DURING MITOSIS OCCURS AFTER THE INITIATION STEP

PA-467 A. Yahalom, Israel, T.H. Kim, A.G. von Arnim, USA, D.A. Chamovitz, Israel ARABIDOPSIS eIF3e IS REGULATED BY THE COP9 SIGNALOSOME AND IMPACTS DEVELOPMENT AND PROTEIN TRANSLATION

PA-468 Y. Yoffe, A. Zinoviev, M. Shapira, Israel THE CAP BINDING COMPLEX IN LEISHMANIA

Vascular biology and angiogenesis

PA-469 Y. Addadi, D. Granot, V. Kalchenko, N. Nevo, M. Nemman, Israel FIBROBLAST RECRUITMENT INTO OVARIAN TUMORS: TWO PHOTON INTRAVITAL MICROSCOPY

PA-470 L. Cohen, M. Cohen, A. Amir, S. Dachir, E. Fishbine, R. Sahar, H. Gutman, V. Givant-Horwitz, J. Turetz, T. Kadar, Israel INHIBITION OF CORNEAL NEOVASCULARIZATION FOLLOWING CHEMICAL INJURY

PA-471 T. Dor, T. Licht, E. Keshet, Israel MODELING NEURONAL LESIONS OF THE PRETERM NEONATE THROUGH CONDITIONAL MANIPULATIONS OF VEGF

PA-472 Y. Dotan, D. Lichtenberg, I. Pinchuk, Israel CARDIOVASCULAR DISEASE IS ONLY WEAKLY ASSOCIATED WITH OXIDATIVE STRESS ACCORDING TO SELECTED INDICES

PA-473 K. Francis, N. Weinberg, Y. Dor, S. Levenberg, Israel ENGINEERING VASCULARIZED PANCREATIC ISLETS IN-VITRO

PA-474 M. Grunewald, Israel/France, J. Vilar, France, A. Itin, Israel, A. Recalde, France, M. Faroja, J-S. Silvestre, Israel THERAPEUTIC ARTERIOGENESIS FOR HIND LIMB ISCHEMIA USING VEGF ACTIVATED BONE MARROW DERIVED MONOCYTES

PA-475 A. Lesman, M. Habib, O. Caspi, Y. Basevitch, A. Gepstein, G. Arbel, I. Huber, L. Gepstein, S. Levenberg, Israel VASCULARIZATION OF ENGINEERED CARDIAC MUSCLE TISSUE FROM HUMAN EMBRYONIC STEM CELLS

PA-476 D. Makarovsky, V. Indenbaum, O. Sagi-Nigel, A. Albeck, S. Yosef, M. Albeck, Israel, M. Nomizu, Japan, H. Kleinman, USA, B. Sredni, Israel THE NOVEL NON TOXIC TELLURIUM COMPOUND SAS BLOCKS ANGIOGENESIS BY INHIBITION OF CELL MIGRATION AND ADHESION: ROLE OF INTERFERENCE WITH ALPHA V BETA 3 ACTIVITY

PA-477 S. Sapoznik, B. Cohen, Y. Tzuman, S. Ben-Dor, M. Neeman, Israel HORMONAL REGULATION OF VEGF-C IN OVARIAN CANCER

78 Poster Session A – Royal Beach (continued)

PA-478 T. Lange, R. Zidon, O. Kessler, G. Neufeld, Israel SEMAPHORIN-3C INHIBITS ANGIOGENESIS AND HINDERS TUMOR DEVELOPMENT

PA-479 K. Ziv, V. Kalchenko, Israel, K. Walsh, L.E. Benjamin, USA, M. Neeman, Israel LYMPHATIC EXPANSION INDUCED BY ENDOTHELIAL AKT1 PRECEDES VASCULAR EXPANSION

PA-480 Withdrawn

79 WEDNESDAY, JANUARY 30, 2008

17:30 – 20:00 Poster Session B Zone 1, Herods Forum

microRNA

PB-1 N. Aizenberg, M. Greenberg, O. Carmi, E. Meiri, A. Levi, Z. Bentwich, Y. Shemer Avni, Israel EPSTEIN BARR VIRUS ENCODED microRNA FROM THE BHRF1-CLUSTER IS INVOLVED IN VIRAL SUPPRESSION DURING LATENCY

PB-2 N. Bar, R. Dikstein, Israel TRANSCRIPTION REGULATION OF microRNA GENES

PB-3 M. Biton, A. Levin, M. Slyper, E. Pikarsky, Y. Ben-Neriah, Israel THE RNAi/microRNA PATHWAY INVOLVEMENT IN GUT IMMUNITY HOMEOSTASIS

PB-4 R. Brosh, A. Liran, N. Goldfinger, V. Rotter, Israel REGULATION OF micro-RNA EXPRESSION BY THE p53 TUMOR SUPPRESSOR

PB-5 A. Cohen, M. Shmoish, L. Levi, U. Cheruti, B. Sivan, E. Lubzens, Israel microRNA EXPRESSION ASSOCIATED WITH ESTROGEN SUGGESTS A ROLE FOR microRNAs IN FISH VITELLOGENESIS

PB-6 N. Elefant, Y. Altuvia, N. Stern-Ginossar, O. Mandelboim, H. Margalit, Israel HOST-PATHOGEN CROSS-TALK VIA microRNA

PB-7 L.M. Friedman, G. Toren, A. Dror, E. Hornstein, K.B. Avraham, Israel microRNAs IN THE DEVELOPING MOUSE INNER EAR

PB-8 N. Gefen, Israel, V. Binder, Israel/Germany, A. Novosel, Germany, M. Morrow, O. Williams, UK, A. Borkhardt, Germany, S. Izraeli, Israel microRNAs AND CHROMOSOME 21 LEUKEMIAS

PB-9 B. Gradus, E. Hornstein, Israel MiRNA ROLE IN REGULATING BONE AND CARTILAGE DEVELOPMENT AND MAINTENANCE

PB-10 D. Zrihan, A. Granit, M.A. Cohen, B. Reubinoff, O. Einstein, T. Ben-Hur, Y. Smith, T. Siegal, I. Lavon, Israel COMPARISON BETWEEN microRNA SIGNITURE OF GLIAL TUMORS, NEURONAL PROGENITOR CELLS AND NORMAL ADULT BRAIN

PB-11 M. Hameiri-Grossman, S. Avigad, I.J. Cohen, S. Ash, A. Weizman, I. Yaniv, Israel micro-RNA ANALYSIS IDENTIFIED THE INVOLVEMENT OF RAS PATHWAY IN EWING SARCOMA TUMORS

PB-12 A. Israel, E. Galun, R. Sharan, E. Ruppin, Israel SOME HUMAN CANCERS ARE CHARACTERIZED BY A MAJOR INCREASE OF microRNA ACTIVITY

PB-13 S. Kredo, T. Melkman Zehavi, R. Oren, E. Hornstein, Israel THE ROLE OF micro-RNAs IN REGULATING PANCREATIC GENES

PB-14 H. Benjamin, Israel microRNAs AS A DIAGNOSTIC TOOL FOR NON SMALL CELL LUNG CANCER

PB-15 D. Levin, E. Hornstein, Israel microRNAs IN THE Hox CLUSTER

PB-16 M. Mann, Israel, R. Agami, The Netherlands, B. Geiger, E. Hornstein, Israel THE ROLE OF MICRO-RNA IN OSTEOCLAST DIFFERENTIATION AND FUNCTION

PB-17 T.J. Melkman-Zehavi, S. Kredo, R. Oren, I. Alon, Y. Dor, Israel, K. Kaestner, USA, E. Hornstein, Israel microRNA INVOLVEMENT IN REGULATING BETA CELL BIOLOGY

PB-18 E. Mor, G. Toren, L.M. Friedman, K.B. Avraham, Israel THE EFFECT OF microRNAs ABSENCE IN INNER EAR HAIR CELLS

80

Poster Session B – Herods Forum (continued)

PB-19 R. Oren, S. Kredo, T. Melkman, E. Hornstein, Israel ANALOGOUS DEVELOPMENTAL NETWORK OF THE PANCREAS AND THE INTESTINE

PB-20 N. Raver-Shapira, E. Marciano, E. Meiri, Y. Spector, N. Rosenfeld, N. Moskovits, Z. Bentwich, M. Oren, Israel TRANSCRIPTIONAL ACTIVATION OF miR-34a CONTRIBUTES TO p53-MEDIATED APOPTOSIS

PB-21 N. Sade, Israel SILENCING THE WHOLE AQUAPORIN AtPIP1 SUB FAMILY USING ARTIFICIAL MICRORNA REVEALS ITS ROLE IN WHOLE PLANT WATER RELATION REGULATION

PB-22 A. Sas-Chen, R. Avraham, M. Kertesz, E. Segal, Y. Yarden, Israel microRNAs AS REGULATORS OF THE ErbB NETWORK

PB-23 A. Schlesinger, B. Gradus, E. Hornstein, Israel micro-RNAs PLAY AN ESSENTIAL ROLE IN CRANIOFACIAL DEVELOPMENT

PB-24 R. Shalgi, D. Lieber, M. Oren, Y. Pilpel, Israel GLOBAL AND LOCAL ARCHITECTURE OF THE MAMMALIAN microRNA–TRANSCRIPTION FACTOR REGULATORY NETWORK

PB-25 N. Yerushalmi, A. Chajut, K. Ashkenazi, S. Tabak, H. Benjamin, D. Cohen, Israel, E.G. Marcusson, C.C. Esau, S.M. Freier, C.F. Bennett, USA THE USE OF ANTISENSE OLIGONUCLEOTIDESS AGAINST miRNA AS A POTENTIAL THERAPY FOR HEPATOCELLULAR CARCINOMA

PB-26 G. Tzur, E. Meiri, O. Barad, A. Levy, Y. Spector, Z. Bentwich, L. Mizrahi, M. Katzenellenbogen, B.E. Reubinoff, E. Galun, Israel MicroRNA EXPRESSION PATTERNS AND FUNCTION IN ENDODERMAL DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS

Molecular mechanism of transcriptional regulation

PB-27 Y. Adamovich, Israel, M. Ben-Yehoyada, USA, N. Reuven, Y. Shaul, Israel p73 PHOSPHORYLATION CODE: EVIDENCE FOR A BINARY MODULE

PB-28 T. Avnit-Sagi, L. Kantorovich, S. Kredo, E. Hornstein, M.D. Walker, Israel IDENTIFICATION AND CHARACTERIZATION OF THE PROMOTER OF miR-375, A PANCREAS SPECIFIC micro-RNA

PB-29 K. Bahar, R. Bartoov-Shifman, M.D. Walker, Israel IDENTIFICATION OF A NOVEL MECHANISM OF TRANSCRIPTION REGULATION IN PANCREATIC BETA CELLS

PB-30 E. Efrati, O. Ben-David, J. Rozenfeld, I. Zelikovic, Israel PARACELLIN-1-MEDIATED TUBULAR MAGNESIUM TRANSPORT IS TRANSCRIPTIONALLY REGULATED BY CYCLOSPORIN A

PB-31 R. Ben-Haroush Schyr, Y. Shabtai, Israel, K. Correia, C.S. Shashikant, R. Krumlauf, USA, A. Fainsod, Israel Cdx1 IS A REQUIRED ACTIVATOR OF Hox EXPRESSION DURING GASTRULATION

PB-32 H. Besserglick-Solomon, Y. Buganim, Y. Rais, I. Nachmany, D. Kistner, I. Kogan, M. Cohen, M. Yaskavich, N. Adam, N. Goldfinger, Y. Kloog, V. Rotter, Israel THE CROSS-TALK BETWEEN WILD-TYPE p53 AND H-Ras IN THE TRANSFORMATION PROCESS

PB-33 I. Bobilev, V. Rossova, J. Levy, Y. Sharoni, M. Danilenko, Israel THE ROLE OF Nrf2/ARE AND AP-1 REDOX-SENSITIVE TRANSCRIPTION SYSTEMS IN THE ENHANCEMENT OF LEUKEMIC CELL DIFFERENTIATION

PB-34 Withdrawn

81 Poster Session B – Herods Forum (continued)

PB-35 Y. Buganim, E. Kalo, R. Brosh, I. Nachmany, Y. Rais, P. Stambolsky, T. Xiaohu, M. Milyavsky, I. Shats, M. Kalis, N. Goldfinger, V. Rotter, Israel MUTANT p53 GAIN OF FUNCTION IN THE PKC PATHWAY: A CROSS-TALK BETWEEN MUTANT p53 AND ATF3

PB-36 R. Elfakess, R. Dikstein, Israel TTIE, A CORE PROMOTER ELEMENT THAT LINKS TRANSCRIPTION AND TRANSLATION

PB-37 M. Elgart, V. Oron-Karni, Y. Oschry, G. Rechavi, R. Ashery-Padan, Israel ELUCIDATING THE TRANSCRIPTIONAL TARGETS OF Pax6 IN MAMMALIAN RETINOGENESIS

PB-38 S. Elizur, S. Selig, Y. Bergman, H. Cedar, Israel MECHANISM INVOLVED IN ESTABLISHMENT OF RIBOSOMAL GENES ASYNCHRONOUS REPLICATION PATTERN

PB-39 B. Garfinkel, N. Sher, M. Ben-Zimra, J. Orly, Israel HETEROGENEOUS NUCLEAR RIBONUCLOPROTEIN K: A NOVEL PLACENTA-SPECIFIC REPRESSOR OF STEROIDOGENESIS

PB-40 K. Gazit, R. Dikstein, Israel CHARACTERIZATION OF THE BIOCHEMICAL AND FUNCTIONAL DNA BINDING ACTIVITY OF TAF4b-TAF12

PB-41 M. Golan-Mashiach, R. Dikstein, E. Shapiro, Israel ELUCIDATING THE MOLECULAR REGULATION OF THE CLUSTERED PROTOCADHERIN

PB-42 V. Gurevich, Y. Kassir, Israel CORRELATION BETWEEN EXPRESSION PATTERN OF THE MASTER REGULATOR GENE IME1 AND EFFICIENCY OF MEIOSIS IN S. CEREVISIAE

PB-43 M. Ionescu, Israel, M. Imshimizu, Japan, M. Elgrably-Weiss, A. Rasouly, S. Belkin, Israel SIMILAR AND OPPOSING REGULATION OF yjbEFGH OPERON BY SIGMA FACTORS IN-VIVO AND IN-VITRO

PB-44 D. Kachanovsky, J. Hirschberg, Israel GENETIC ANALYSIS OF EPISTASIS IN THE CAROTENOID BIOSYNTHESIS PATHWAY

PB-45 Y. Lerenthal, M. Salton-Morgenstern, Israel, N. Gueven, Australia, M. Gana-Weisz, Israel, M.F. Lavin, Australia, Y. Shiloh, Israel THE TRANSCRIPTION FACTOR Sp1 IS AN ATM EFFECTOR IN THE DNA DAMAGE RESPONSE

PB-46 A. Levy, G. Hershkovits, M. Salmon-Divon, M. Eyal, D.J. Katcoff, Israel FUNCTIONAL ANALYSIS OF THE YEAST LINKER HISTONE Hho1p AS MONITORED BY TRANSCRIPTIONAL SILENCING IN RIBOSOMAL DNA

PB-47 J. Lieman-Hurwitz, M. Haimovich, A. Kaplan, Israel HOW DOES THE AMBIENT CO2 CONCENTRATION REGULATE GENE EXPRESSION?

PB-48 O. Margalit, N. Shental, A. Harmelin, D. Givol, G. Rechavi, E. Domany, N. Amariglio, Israel IDENTIFICATION OF p53 IN VIVO PRIMARY TARGET GENES USING MICROARAYS IN A MURINE MODEL

PB-49 A. Matityahu, Y. Hadar, C.G. Dosoretz, P.A. Belinky, Israel GENE SILENCING BY RNA INTERFERENCE IN THE WHITE-ROT FUNGUS PHANEROCHAETE CHRYSOSPORIUM

PB-50 R. Meyuhas, E. Pikarsky, E. Tavor, J. Hochman, A. Honigman, Israel A KEY ROLE FOR CREB IN HYPOXIA MEDIATED ACTIVATION OF THE ANGIOGENESIS FACTOR CYR61, IN TUMOR CELLS

PB-51 A. Molchadsky, I. Shats, N. Goldfinger, R. Sarig, M. Feldman, M. Pevsner-Fischer, D. Zipori, V. Rotter, Israel p53, A CELL DIFFERENTIATION REGULATOR

82 Poster Session B – Herods Forum (continued)

PB-52 Y. Morag, H. Salman, M. Danilenko, J. Levy, Y. Sharony, Israel MOLECULAR MECHANISMS FOR THE ACTIVATION OF THE NRF2/ARE TRANSCRIPTION SYSTEM (1)

PB-53 I. Ricardo-Lax, R. Elfakess, R. Dikstein, Israel CHARACTERIZATION OF A NOVEL TRANSCRIPTION AND TRANSLATION REGULATORY MOTIF

PB-54 H. Salman, Y. Morag, M. Danilenko, J. Levy, Y. Sahroni, Israel MOLECULAR MECHANISMS FOR THE ACTIVATION OF THE NRF2/ARE TRANSCRIPTION SYSTEM (2): A METHOD TO PREDICT SYNERGY BETWEEN VARIOUS PHYTO-NUTRIENTS

PB-55 H. Schayek, Israel, K. Haugk, L. TRUE, S.R. Plymate, USA, H. Werner, Israel BRCA1 IS EXPRESSED IN THE PROSTATE GLAND AND CONTROLS IGF-I RECEPTOR GENE EXPRESSION

PB-56 G. Shalev-Malul, J. Lieman-Hurwitz, Y. Viner-Mozzini, A. Sukenik, A. Gaathon, M. Lebendiker, A. Kaplan, Israel AN AbrB-LIKE PROTEIN MIGHT BE INVOLVED IN THE REGULATION OF CYLINDROSPERMOPSIN PRODUCTION IN APHANIZOMENON OVALISPORUM

PB-57 E. Shema, I. Tirosh, M. Oren, Israel ROLES OF H2B UBIQUITYLATION IN TRANSCRIPTIONAL REGULATION

PB-58 E. Simon, T. Gildor, D. Kornitzer, Israel REGULATION OF THE TRANSCRIPTION FACTOR CaGcn4 BY AUTOPHOSPHORYLATION OF ITS COGNATE CYCLIN

PB-59 H. Sinvani, S. Moshonov, R. Dikstein, Israel THE CORRELATION BETWEEN CORE PROMOTER AND BASIC GENE FEATURES

PB-60 G. Smooha, Y. Birger, L. Rainis, J. Jacob-Hirsch, S. Izraeli, Israel ERG TRANSCRIPTION FACTOR INVOLVEMENT IN HEMATOPOIETIC DIFFERENTIATION AND LEUKEMIA

PB-61 L. Adler, E. Efrati, O. Tal, I. Zelikovic, Israel THE PENDRIN GENE, PDS, IS TRANSCRIPTIONALLY REGULATED BY AMBIENT pH AND CHLORIDE

PB-62 I. Tirosh, N. Barkai, Israel PATTERNS OF PROMOTER NUCLEOSOME OCCUPANCY INFLUENCES THE DYNAMIC REGULATION OF GENE EXPRESSION

PB-63 G. Yarden, R. Elfakess, R. Dikstein, Israel CHARACTERIATION OF A NOVEL MAMMALIAN CORE PROMOTER ELEMENT

Pattern formation and morphogenesis

PB-64 O. Barad, N. Barkai, E. Hornstein, Israel ROBOUST LATERAL INHIBITION SELECTION PROCESS

PB-65 D. Ben-Zvi, A. Fainsod, B.Z. Shilo, N. Barkai, Israel SIZE-DEPENDENT SCALING OF BMP ACTIVATION GRADIENT: IMPLICATIONS FOR REGENERATION AND AXIS-DUPLICATION

PB-66 Y. Berger, A. Brand, N. Sirding, Y. Eshed, J.P. Alvarez, Z. Amsellem, N. Ori, Israel ROLE OF GOBLET IN LEAF PATTERNING IN TOMATO (SOLANUM LYCOPERSICUM)

PB-67 I. Efroni, E. Blum, Y. Eshed, Israel A DYNAMIC MATURATION SCHEDULE REGULATES ARABIDOPSIS LEAF SHAPE AND SIZE

PB-68 R. Elbaum, Israel, P. Fratzl, Germany THE MICROSCOPIC STRUCTURES RESPONSIBLE FOR THE HYGROSCOPIC MOVEMENT OF WHEAT AWNS

83 Poster Session B – Herods Forum (continued)

PB-69 A. Fainsod, S. Zins Rousso, R. Ben-Haroush Schyr, N. Koutsi-Urshanski, Israel, C. Niehrs, Germany THE TRANSITION FROM PLURIPOTENCY TO GASTRULATION IN THE EMBRYO REQUIRES THE INTERACTION BETWEEN Cdx1 AND Oct4

PB-70 B. Gildor, R. Massarwa, E.D. Schejter, B.Z. Shilo, Israel ACTIN NUCLEATION BY THE SCAR/WAVE COMPLEX IS ESSENTIAL IN EMBRYONIC MYOBLAST FUSION IN DROSOPHILA

PB-71 M. Gur, Israel, C. Niehrs, Germany, A. Fainsod, Israel EARLY ORGANIZER-SPECIFIC RETINOIC ACID SIGNALING IS REQUIRED FOR HEAD FORMATION

PB-72 Withdrawn

PB-73 G. Kayam, D. Sela Donenfeld, Israel THE INVOLVEMENT OF Pax6 IN EARLY HINDBRAIN DEVELOPMENT IN CHICK EMBRYO

PB-74 Y. Kinel-Tahan, V. Freger, A. Levine, R. Wides, Israel Odz FAMILY GENES ARE REQUIRED FOR EYE PATTERNING

PB-75 J. Kosonovsky, E. Monsonego Ornan, D. Sela Donenfeld, Israel THE ROLE OF MATRIX METALLOPROTEASE 9 IN NEURAL CREST CELL MIGRATION IN THE CHICK EMBRYO

PB-76 K. Laviv Weisinger, D. Sela Donenfeld, Israel, D. Wilkinson, UK THE ANTAGONISTIC INTERACTION BETWEEN FGF AND BMP SIGNALS DURING HINDBRAIN DEVELOPMENT

PB-77 J. Magenheim, E. Keshet, Y. Dor, Israel BLOOD VESSELS CONTROL BRANCHING MORPHOGENESIS OF THE PANCREAS

PB-78 H. Neuman, N. Kantz, H. Gingold, S. Brenner, Z. Avraham, R. Wides, Israel Odz/TenM: AN ANCIENT ANIMAL GENE FAMILY REQUIRED FOR SEGMENTATION

PB-79 E. Nissim-Eliraz, A. Mansour, S. Zisman, T. Golan-Lev, O. Schatz, A. Klar, N. Ben-Arie, Israel Nato3, A NOVEL bHLH TRANSCRIPTION FACTOR, IS EXPRESSED IN THE DEVELOPING SPINAL CORD, AND ACTS VIA THE Shh SIGNALING PATHWAY

PB-80 G. Pelhovich, S. Omer, D. Gutnick, Israel VITAMIN K MEDIATES PATTERN FORMATION IN UNDOMESTICATED BACILLI

PB-81 E. Preger, H. Barak, N. Guttmann-Raviv, R. Reshef, Israel INTERPLAY BETWEEN ACTIVIN, RETINOIC ACID AND HOX GENES DETERMINE THE FORMATION OF THE KIDNEY MORPHOGENETIC FIELD

PB-82 N. Rakovitsky, M. Safra, Y. Michealson, R. Wides, Israel Odz-FAMILY GENES ARE NECESSARY FOR DROSOPHILA WING VEIN PATTERNING, AND FOR WING MARGIN ESTABLISHMENT IN CONCERT WITH NOTCH SIGNALLING

PB-83 D. Rosin-Grunewald, O. Barad, N. Barkai, E. Hornstein, Israel REAL TIME IMAGING OF DROSOPHILA NEURAL PRECURSORS SELECTION PROCESS

PB-84 O. Schatz, E. Golenser, N. Ben-Arie, Israel THE TRANSPARENT EMBRYO: CLEARING AND PHOTOGRAPHY OF X-GAL STAINED WHOLE MOUSE EMBRYOS

PB-85 R.G. James, C.N. Kamei, T.M. Schultheiss, Israel SIGNALS WHICH REGULATE FORMATION OF THE INTERMEDIATE MESODERM

PB-86 E. Shani, L. Ben-Yaakov, O. Yanai, Y. Borko, Y. Beger, H. Melnik, J.P. Alvarez, N. Ori, Israel ARABIDOPSIS CLASS I HOMEBOX (KNOXI) GENES ACTIVATE CYTOKININ BIOSYNTHESIS

84 Poster Session B – Herods Forum (continued)

PB-87 Z. Tamari, N. Barkai, Israel REDUCTION OF NOISE IN READING THE Bicoid MORPHOGEN GRADIENT

PB-88 S. Yogev, E. Schejter, B. Shilo, Israel DROSOPHILA EGFR SIGNALING IS MODULATED BY DIFFERENTIAL COMPARTMENTALIZATION OF RHOMBOID INTRA-MEMBRANE PROTEASES

85 17:30 – 20:00 Poster Session B Zone 2, Dan

Bioremediation and conservation of the environment

PB-89 A. Biran, H. Ben Yoav, R. Pedahzur, S. Yagur-Kroll, Y. Shacham-Diamant, S. Belkin, Israel DIPCHIP: A NOVEL BIO-ELECTROCHEMICAL GENOTOXICITY DETECTION SYSTEM

PB-90 T. Elad, S. Magrisso, I. Benovici, S. Belkin, Israel A WHOLE-CELL ARRAY FOR ENVIRONMENTAL MONITORING: CELL IMMOBILIZATION AND DATA ANALYSIS

PB-91 A. Karpol, E.A. Bayer, Israel STRUCTURAL ROLE FOR CALCIUM IN THE TYPE-III DOCKERIN

PB-92 S. Lazar, S. Chapman, R. Sahar, J. Kapon, I. Egoz, E. Bloch-Shilderman, Israel ACUTE ORGANOPHOSPHATE INSECTICIDE POISONING: HISTOPATHOLOGICAL AND BIOCHEMICAL ANALYSIS

PB-93 S. Melamed, Israel, L. Ceriotti, Italy, S. Yagur-Kroll, Israel, P. Colpo, Italy, S. Belkin, Israel WHOLE-CELL MICROBIAL REPORTERS FOR AGRICULTURAL ENDOCRINE DISRUPTORS AND OTHER TOXICANTS

PB-94 O. Segev, Israel, W. Meusel, Germany, A. Kushmaro, Israel BIODEGRADATION OF DIBROMONEOPENTYL GLYCOL AND TRIBROMONEOPENTYL ALCOHOL BY A COMMON BACTERIAL CONSORTIUM

PB-95 S. Yagur-Kroll, T. Elad, S. Belkin, Israel STRATEGIES FOR IMPROVEMENT OF BIOLUMINESCENT BACTERIAL SENSOR PERFORMANCE

Cancer biology and therapeutics: molecular mechanisms and emerging therapeutic strategies

PB-96 I. Abd-Elrahman, B. Nachmias, I. Lazar, K. Hershko, R. Perlman, D. Ben-Yehuda, Israel LIVIN AS A POTENTIAL THERAPEUTIC TARGET FOR THE TREATMENT OF MALIGNANCY

PB-97 A. Algamas-Dimantov, I. Peri, B. Schwartz, Israel THE ROLE OF HEPATOCYTE NUCLEAR FACTOR 4ALPHA (HNF-4ALPHA) IN COLORECTAL CANCER

PB-98 Y. Amir, M. Shmueli, D. Segal, E. Gazit, Israel CONDITIONAL SILENCING OF THE VON HIPPEL-LINDAU TUMOR SUPPRESSOR GENE IN DROSOPHILA MELANOGASTER

PB-99 I. Azran-Shaish, M. Aboud, Israel HTLV-1 TAX INDUCED NF-kappaB ACTIVATION IS SYNERGISTICALLY ENHANCED 12- O- TETRADECANOYLPHORBOL-13-ACETATE: MECHANISM AND IMPLICATIONS FOR TAX ONCOGENICITY

PB-100 U. Barash, N. Ilan, I. Vlodavsky, Israel ROLE OF HYPOXIA IN HEPARANASE GENE AND PROTEIN REGULATION

PB-101 B. Barkan, R. Haklay, G. Elad-Sefadia, R. Stein, Y. Kloog, Israel THE Ras INHIBITOR FARNESYL THIOSALICYTIC AS A POTENTIAL THERAPUTIC APPROACH FOR NEUROFIBROMATOSIS TYPE 1

PB-102 M. Bassani Sternberg, A. Admon, Israel CROSS PRESENTED MHC PEPTIDOME

PB-103 I. Ben-Porath, USA/Israel, M.W. Thomson, V.J. Carey, R. Ge, G.W. Bell, A. Regev, R.A. Weinberg, USA AN EMBRYONIC STEM CELL-LIKE GENE EXPRESSION SIGNATURE IN POORLY DIFFERENTIATED AGGRESSIVE HUMAN TUMORS

PB-104 E. Bensoussan, A. Meirovitz, I. Lerner, I. Vlodavsky, M. Elkin, Israel RADIATION INDUCES INVASIVENESS OF PANCREATIC CANCER VIA UPREGULATION OF HEPARANASE

86 Poster Session B – Dan (continued)

PB-105 D. Fuchs, A. Bier, D. Zrihan, G. Efroni, B. Zelikovitch, Y. Fellig, T. Siegal, I. Lavon, Israel NOVEL MECHANISM WHEREBY NUCLEAR FACTOR KB MEDIATES DNA DAMAGE REPAIR THROUGH REGULATION OF O6-METHYLGUANINE-DNA-METHYLTRANSFERASE

PB-106 K. Bitton-Worms, A. Aronheim, Israel DIFFERENTIAL MODE OF ACTION OF THE c-Jun DIMERIZATION PROTEIN 2, JDP2, IN DISTINCT HEPATOCELLULAR CARCINOMA MICE MODELS

PB-107 L. Blau, I. Ben-Dror, R. Knirsh, Israel, A.K. Bosserhoff, Germany, L. Vardimon, Israel A POST-TRANSCRIPTIONAL PATHWAY FOR REGULATION OF c-JUN EXPRESSION IN GLIAL TUMOR CELLS

PB-108 V. Brekhman, S. Soueid-Baumgarten, G. Neufeld, Israel A NOVEL THREE-DIMENSIONAL ASSAY FOR STUDYING TUMOR CELLS INVASIVENESS

PB-109 R. Bringer, Y. Azar, R. Or, Israel, E.R. Barnea, USA PIF-1* IMPROVES GRAFT VS. HOST DISEASE (GVHD) WHILE MAINTAINING GRAFT VS. LEUKEMIA (GVL) EFFECT AFTER BONE MARROW TRANSPLANTATION IN MICE

PB-110 M. Brunwasser, D. Ron, Israel CHARACTERIZATION OF HUMAN Sef C ISOFORM

PB-111 R. Kovjazin, L. Carmon, Israel IDENTIFICATION OF A MULTI-EPITOPE THERAPEUTIC VACCINE AGAINST MUC1 EXPRESSING TUMORS UTILIZING BIOINFORMATICS AND REVERSE IMMUNOLOGY

PB-112 A. Castiel, M. Mark-Danieli, Israel, A. Erez, USA, S. Izraeli, Israel THE SIL GENE IS ESSENTIAL FOR MITOSIS AND SURVIVAL OF CANCER CELLS

PB-113 R. Chamias, M. Aboud, Israel INFLUENCE OF TPA ON HTLV-1 LTR

PB-114 I. Shur, C. Choen, D. Benayahu, Israel POTENTIAL ROLE OF SVEP1 IN HOMING OF BREAST CARCINOMA TO THE BONE

PB-115 A.A. Cohen, N. Geva-Zatorsky, E. Eden, N. Perzov, M. Frenkel-Morgenstein, T. Danon, L. Cohen, U. Alon, Israel DYNAMIC PROTEOMICS OF INDIVIDUAL CANCER CELLS IN RESPONSE TO A DRUG

PB-116 B. Cohen, S. Sapoznik, G. Meir, T. Israely, V. Kalchenko, A. Harmelin, S. Ben-Dor, M. Neeman, Israel LENS EPITHELIUM-DERIVED GROWTH FACTOR (LEDGF) REGULATES VEGF-C EXPRESSION, LYMPHANGIOGENESIS AND TUMOR GROWTH

PB-117 S. Cohen, K. Cohen, N. Buchner, R. Laptev, H. Oster, M. Mittelman, M.A. Firer, Israel ISOLATION AND INITIAL FUNCTIONAL VALIDATION OF PEPTIDES SPECIFIC FOR CHRONIC LYMPHOCYTIC LEUKEMIC CELLS

PB-118 R. Nagler, S. Cohen, Israel THE SYNERGISTIC EFFECT OF CIGARETTE SMOKE AND SALIVA ON THE TRANSLOCATOR PROTEIN (TSPO) IN AN IN VITRO MODEL OF LUNG CANCER

PB-119 Y. Cohen, Y. Cohen, O. Leshem, R. Berger, Israel STUDYING THE MECHANISM OF ANDROGEN RECEPTOR DEPENDENCY IN HUMAN PROSTATE CANCER

PB-120 S. Dadon, O. Sagi, V. Fraifeld, J. Kapelushnik, A. Cohen, E. Cagnano, E. Maor, M. Wolfson, Israel Shc EXPRESSION IN HUMAN NEUROBLASTOMAS AND ASTROCYTOMAS

PB-121 E. Doron, B. Solomon, Israel RESTORATION OF P53 WILD TYPE PHENOTYPE TO MUTANT P53 VIA SINGLE CHAIN ANTIBODY

PB-122 N. Dror, T. Barliya, M. Mandel, Z. Hazan, I. Tsarfaty, G. Lavie, Israel HYPERICIN REPRESENTSA NOVEL PLATFORM FOR MODULATING CELL BEHAVIOR AND PROLONGED STABILIZATION OF GLIOMA TUMORS

87 Poster Session B – Dan (continued)

PB-123 G. Eisenberg, A. Machlenkin, I. Grinberg, R.S. Goldstein, J. Pitcovski, T. Peretz, E. Yefenof, M. Lotem, S. Frankenburg, Israel IMMUNOLOGICAL ACTIVATION FOLLOWING TRANSCUTANEOUS DELIVERY OF HR-gp100 PROTEIN

PB-124 E. Zehorai, E. Eitan, Israel INFLUENCES OF NEUROTRANSMITTERS ON THE ACTIVITY OF TOPOISOMERASE I IN MOUSE CEREBELLUM

PB-125 S. Fedida-Metula, S. Elhaiany, S. Tsory, S. Segal, M. Hershfinkel, I. Sekler, D. Fishman, Israel TARGETING MEMBRANE RAFTS INHIBITS PROTEIN KINASE B BY DISRUPTING CALCIUM HOMEOSTASIS AND ATTENUATES MALIGNANT PROPERTIES OF MELANOMA CELLS

PB-126 M.A. Firer, R. Laptev, Israel EPITOPE-DRUG CONJUGATES IN THE TARGETED IMMUNOTHERAPY OF B-CELL LEUKEMIAS

PB-127 L. Fux, N. Feibish, C. Geffen, E. Cohen, N. Ilan, I. Vlodavsky, Israel STRUCTURE-FUNCTION APPROACH IDENTIFIES A C-TERMINAL DOMAIN THAT MEDIATES HEPARANASE SECRETION AND SIGNALING

PB-128 H. Gal, L. Trakhtenbrot, A. Nagler, T. Lapidot, T. Ram, N. Amariglio, E. Domany, G. Rechavi, D. Givol, Israel GENE EXPRESSION PROFILING OF CANCER STEM CELLS; STUDIES IN LEUKEMIA AND GLIOBLASTOMA

PB-129 I. Ganmore, D. Bercovich, A. Elimelech, S. Avigad, B. Stark, Y. Birger, S. Izraeli, Israel, IBFM Study Group of Childhood Leukemia COLLABORATION BETWEEN ACTIVATING MUTATIONS IN JAK2 AND TRISOMY 21 IN THE ACUTE LYMPHOBLASTIC LEUKEMIAS OF DOWN SYNDROME (DS)

PB-130 A. Gilert, M. Machluf, Israel VACCINE BASED MICRO PARTICLES DELIVERY SYSTEM FOR MHC CLASS I PRESENTATION

PB-131 C. Glait Santar, P. Ofek, D. Ben Meir, M. Oren, S. Lavi, Israel PROTEIN PHOSPHATASE 2C ALPHA ENABLE p53 ACTIVATION BY PROMOTING Mdm2 AUTO- UBIQUITINATION

PB-132 S. Escobar Alvarez, Y. Goldgur, C. Antczak, G. Yang, O. Ouerfelli, H. Djaballah, Y. Li, D. Scheinberg, USA CRYSTAL STRUCTURE OF A NEW CANCER TARGET, HUMAN PEPTIDE DEFORMYLASE WITH ITS INHIBITORS

PB-133 L. Goldshaid, Y. Salomon, A. Scherz, Israel VASCULAR-TARGETED IMAGING OF PRIMARY MAMMARY CARCINOMA TUMOR MODEL WITH NOVEL RGD-BACTERIOCHLOROPHYLL DERIVATIVES

PB-134 Y. Buganim, I. Goldshtein, M. Miliyavsky, E. Kalo, V. Rotter, Israel LOCALIZATION OF THE 17q BREAKPOINT OF A der(X)t(17;X) TRANSLOCATION IN HUMAN PRIMARY DIPLOID FIBROBLASTS

PB-135 A. Goren, E. Livne, M. Machluf, Israel POLYMERIC MICROCAPSULES ENTRAPPING MESENCHYMAL STEM CELLS: A NEW APPROCH FOR CANCER THERAPY

PB-136 I. Grinberg, A. Reis, V. Deutsch, D. Rund, R.S. Goldstein, Israel A RAPID AND POWERFUL IN VIVO MODEL FOR STUDYING HUMAN BLOOD MALIGNANCIES I: ESTABLISHMENT OF OPTIMIZED CONDITIONS FOR GRAFTING HEMATOLOGICAL MALIGNANCIES TO TURKEY EMBRYOS

PB-137 I. Grodzovski, H. Lorberboum-Galski, Israel OVERCOMING MULTI-DRUG RESISTANCE IN CANCER USING TARGETED CHIMERIC PROTEINS

PB-138 Y. Haberman, N. Amariglio, G. Rechavi, E. Eisenberg, Israel TRINUCLEOTIDE REPEATS ARE PREVALENT AMONG CANCER-RELATED GENES

88 Poster Session B – Dan (continued)

PB-139 M. Hayun, Y. Naor, M. Weil, M. Albeck, A. Peled, J. Don, N. Haran-Ghera, B. Sredni, Israel THE IMMUNOMODULATOR AS101 INDUCES GROWTH ARREST AND APOPTOSIS IN MULTIPLE MYELOMA: ASSOCIATION WITH THE Akt/SURVIVIN PATHWAY

PB-140 M. Hochberg, L.T. Gilead, A. Ingber, A. Panet, Israel A NOVEL SYSTEM TO STUDY THERAPEUTIC APPLICATIONS FOR GENE THERAPY OF NON- MELANOMA SKIN CANCERS

PB-141 G. Horn, A. Gaziel, D.H. Wreschner, M. Ehrlich, N.I. Smorodinsky, Israel ACTIVATION OF EGFR PATHWAY BY MUC1/SEC LEADS TO EPITHELIAL TO MESENCHYMAL TRANSITION

PB-142 D. Yelin, G. Hout Siloni, D. Dominissini, N. Rosenfeld, G. Rechavi, N. Amariglio, Y. Cohen, Israel HIGH-THROUGHPUT PROFILING OF ONCOGENIC MUTATION IN EPITHELIAL OVARIAN CANCER – A NEW APPROACH FOR BIOMARKER DISCOVERY

PB-143 S. Kahana, Israel, S. Finnis, W. Lu, S. Brodie, A.C. de Carvalho, T. Mikkelsen, USA, C. Brodie, Israel MG-132 SENSITIZES TRAIL-RESISTANT GLIOMA CELLS AND GLIOMA STEM CELLS BY THE CLEAVAGE AND DOWN-REGULATION OF PKCepsilon

PB-144 Withdrawn

PB-145 R.D. Petrova, N. Ruimi, H. Khamaisi, S. Sussan, S.P. Wasser, E. Nevo, A.Z. Reznick, J. Mahajna, Israel INHIBITORY EFFECTS OF MARASMIUS OREADES FRACTIONS ON NF-kB ACTIVATION PATHWAY

PB-146 L. Kisslov, N. Hadad, R. Levy, Israel THE ROLE OF CYTOSOLIC PHOSPHOLIPASE A2 ALPHA IN PROLIFERATION OF HT-29 COLON CANCER CELLS

PB-147 N. Klopstok, M. Katzenellenbogen, O. Pappo, D. Olam, E. Domany, E. Galun, D. Goldenberg, Israel MOLECULAR MECHANISMS OF HEPATOCARCINOGENESIS IN MDR2-KO/HCV-TG MICE

PB-148 R. Knirsh, I. Ben-Dror, Israel, B. Spangler, A.K. Bosserhoff, Germany, L. Vardimon, Israel CELL-CELL CONTACT INHIBITS THE EXPRESSION OF c-JUN BY A POSTTRANSCRIPTIONAL MECHANISM

PB-149 D. Kolodkin-Gal, G. Zamir, Y. Edden, E. Pikarsky, A. Pikarsky, H. Haim, Y.S. Haviv, A. Panet, Israel NEW INSIGHT ON VIRAL VECTORS TARGETING COLON-CARCINOMA

PB-150 I. Lavi, D. Levinson, I. Peri, L. Nimri, Y. Hadar, B. Schwartz, Israel PROAPOPTOTIC, ANTIINFLAMMATORY AND ANTICARCINOGENIC PROPERTIES OF ORALLY ADMINISTERED GLUCANS HARVESTED FROM PLEUROTUS PULMONARIUS FRUITING BODIES VERSUS MYCELIUM GROWN IN SUBMERGED CULTURE

PB-151 G. Lavie, Israel/USA, T. Barliya, USA, N. Dror, Israel, M. Blank, USA, L. Trakhtenbrot, Z. Hazan, M. Mandel, Israel EXO-UBIQUITINATION: PERIHYDROXYLATED PERYLENE QUINONES ARE EXOGENOUS REAGENTS THAT TARGET SPECIFIC CELLULAR PROTEINS FOR DEGRADATION THROUGH FORCED UBIQUITINATION. A NOVEL CLASS OF ANTI-CANCER AGENTS

PB-152 K. Leibson, E. Eitan, I. Har-Vardi, G. Potashnik, E. Priel, Israel ESTROGEN PROTECTS THE ENDOMETRIUM FROM DAMAGES CAUSED BY ANTI CANCER DRUGS

PB-153 I. Lerner, Y. Sherman, E. Zcharia, I. Vlodavsky, M. Elkin, Israel HEPARANASE INVOLVEMENT IN INFLAMMATORY BOWEL DISEASE RELATED CARCINOGENESIS

PB-154 O. Leshem, Y. Cohen, G. Smooha, V. Rotter, S. Izraeli, Y. Cohen, R. Berger, Israel THE ROLE OF ERG TRANSCRIPTION FACTOR IN PROSTATE CANCER

89 Poster Session B – Dan (continued)

PB-155 I. Levi, Israel THE INFLUENCE OF TYPE I DIABETES ON DNA TOPOISOMERASE I ACTIVITY AND REGULATION IN AN ANIMAL MODEL

PB-156 E. Levy-Dahary, Z. Rappoport, D. Arad, O. Shpilberg, I. Levi, I. Nathan, Israel EFFECT OF TRIPHENYLETHYLENES AS POTENTIAL AGENTS FOR CANCER THERAPY; MODE OF ACTION

PB-157 F. Levy-Adam, S. Feld, N. Ilan, I. Vlodavsky, Israel HEPARANASE FACILITATES CELL ADHESION AND SPREADING BY BINDING AND ACTIVATING CELL SURFACE HEPARAN SULFATE

PB-158 H. Lichtig Kinsbruner, D. Avital Gilboa, A. Jackman, L. Sherman, Israel WNT INDUCED BETA-CATENIN/TCF DEPENDENT TRANSCRIPTION IS ENHANCED BY HPV16 E6

PB-159 A. Luria, M. Wolfson, Israel CASPASES 7 AND 10 ARE SPECIFICALLY ACTIVATED BY TAXOL IN OVARIAN CARCINOMA CELLS

PB-160 V. Meltser, Israel, M. Ben-Yehoyada, USA, N. Reuven, Y. Shaul, Israel TYROSINE KINASES AND DNA REPAIR; THE ROLE OF c-Abl

PB-161 Y. Michaeli, Y. Reiter, Israel EXPRESSION HIERARCHY OF T CELL EPITOPES DERIVED FROM MELANOMA DIFFERENTIATION ANTIGENS: UNEXPECTED HIGH LEVEL PRESENTATION OF TYROSINASE- DERIVED PEPTIDE-MHC COMPLEXES REVEALED BY PEPTIDE-SPECIFIC, MHC-RESTRICTED TCR-LIKE ANTIBODIES

PB-162 S. Moshitch-Moshkovitz, Israel, G. D’Orazi, Italy, D. Givol, N. Amariglio, G. Rechavi, Israel HIPK2 AND p53 PLAY A ROLE IN MODULATING MITOCHONDRIAL METABOLISM

PB-163 S. Naffar-Abu-Amara, Z. Kam, B. Geiger, Israel HIGH-THROUGHPUT SCREENING OF CELL MIGRATION, USING QUANTITATIVE ANALYSIS OF PHAGOKINETIC TRACKS

PB-164 S. Natan, G. Stein, Y. Gleitman, H. Judith, I. Tsarfay, G. Tsarfaty, Israel FUNCTIONAL MOLECULAR IMAGING OF Met ONCOGENE AS A TOOL FOR TAILORED THERAPY

PB-165 Y. Nevo-Caspi, M. Safran, A. Lev, N. Amariglio, G. Rechavi, A. Nagler, Israel A MOUSE MODEL FOR MULTIPLE MYELOMA

PB-166 R. Noy, A. Lev, H. Novak, K. Oved, D. Segal, Y. Reiter, Israel TUMOR-SPECIFIC ANTIBODY-MEDIATED TARGETING OF MHC-PEPTIDE COMPLEXES RECRUITING ANTI-VIRAL OR ANTI TUMOR LYMPHOCYTES INDUCES REGRESSION OF HUMAN TUMOR XENOGRAFTS IN VIVO

PB-167 L. Nuttman, L. Roiz, P. Smirnoff, S. Lapidot, M. Dekel, O. Shoseyov, Israel CLONING, EXPRESSION, PURIFICATION AND CHARACTERIZATION OF TRUNCATED HUMAN RNase T2 IN E.COLI

PB-168 R. Peleg, O. Cohen, E. Priel, Israel ERLOTINIB AS AN INHIBITOR OF TYPE I TOPOISOMERASE IN PROSTATE AND BREAST CANCER CELL LINES: EFFICACY OF COMBINED ERLOTINIB AND TOPOISOMERASES INHIBITORS TREATMENTS

PB-169 Withdrawn

PB-170 G. Pines, Y. Yarden, Israel CHARACTERIZATION OF EGF RECEPTOR CARBOXYL TERMINAL MUTATIONS IN GLIOBLASTOMA

90 Poster Session B – Dan (continued)

PB-171 T. Potikha, O. Pappo, D. Olam, E. Galun, D. Goldenberg, Israel COMPLEX REGULATION OF HEPATOCYTE PROLIFERATION IN EARLY STAGES OF INFLAMMATION-INDUCED HEPATOCARCINOGENESIS

PB-172 D. Rabinovich, N. Reuven, Y. Shaul, Israel THE INVOLVEMENT OF CHROMATIN REMODELING PROTEINS IN CANCER; THE HBXAP MODEL

PB-173 A. Reis, I. Grinberg, V. Deutsch, D. Rund, R.S. Goldstein, Israel A RAPID AND POWERFUL IN VIVO MODEL FOR STUDYING HUMAN BLOOD MALIGNANCIES II: ENGRAFTMENT OF HUMAN LEUKEMIAS, MYELOMAS AND LYMPHOMA IN TURKEY EMBRYOS

PB-174 L. Roiz, P. Smirnoff, B. Schwartz, O. Shoseyov, Israel A RECOMBINANT HUMAN RNASET2 GLYCOPROTEIN WITH ANTITUMORIGENIC AND ANTIANGIOGENIC EFFECTS.

PB-175 V. Rossova, I. Bobilev, J. Levy, Y. Sharoni, M. Danilenko, Israel INTERPLAY BETWEEN Nrf2/ARE, AP-1 AND VDR TRANSCRIPTION SYSTEMS IN DIFFERENTIATING AML CELLS

PB-176 S. Rotem, C. Katz, H. Benyamini, A. Friedler, Israel INTARMOLECULAR INTERACTION IN ASPP2 MEDIATE ITS ITERMOLECULAR INTERACTIONS

PB-177 G. Sarfati, R.N. Apte, S. Cohen, Israel TARGETING OF LUNG METASTASES IN MELANOMA CANCER WITH LIGAND-SPECIFIC NANOPARTICLES

PB-178 B. Schwartz, T. Jaffe, Israel THE ROLE OF OBESITY IN ADVANCED COLORECTAL CANCER

PB-179 A. Shabtay, H. Sharabani, Z. Barvish, J. Levy, Y. Sharoni, M. Danilenko, Israel SYNERGISTIC ANTILEUKEMIC EFFECTS OF VITAMIN D DERIVATIVES AND ROSEMARY POLYPHENOLS IN A MOUSE MODEL OF ACUTE MYELOID LEUKEMIA

PB-180 E. Shahar, J. Pitcovski, R. Gorodetsky, Israel TARGETING AND ACTIVATION OF MONOCYTES DIRECTED TO BREAST CANCER CELLS ENHANCED BY INDUCERS CARRIED BY MICROBEADS

PB-181 N. Yarom, T. Shani, S. Taicher, N. Amariglio, G. Rechavi, L. Trakhtenbrot, A. Hirshberg, Israel CHROMOSOMAL NUMERICAL ABERRATIONS IN ORAL LICHEN PLANUS

PB-182 M. Shatz, R. Reich, M. Liscovitch, Israel CAVEOLIN-1 IS A REGULATOR OF CANCER CELL SURVIVAL, INVASIVENESS AND DRUG RESPONSE

PB-183 Withdrawn

PB-184 I. Skornick, Y. Kalechman, A. Berrebi, B. Sredni, Israel INTERFERENCE WITH THE INTERACTION OF VLA-4 AND FIBRONECTIN IN AML CELLS BY THE TELLURIUM COMPOUND AS101 RESULTS IN THEIR SENSITIZATION TO CHEMOTHERAPY

PB-185 T. Eilon, I. Barash, Israel ONCOGENESIS IN MAMMARY EPITHELIAL CELLS OF TRANSGENIC MICE EXPRESSING STAT5 VARIANTS: CONDITIONS FOR CANCER DEVELOPMENT AND CHARACTERIZATION OF GENE EXPRESSION PROFILES IN TUMORS

PB-186 S. Itzhak, A. Tichon, A. Gazit, S. Slavin, E. Priel, Israel NOVEL TELOMERASE ACTIVATORS

PB-187 L. Trakhtenbrot, M. Koren-Michowitz, I. Hardan, S. Oren, G. Yshoev, A. Nagler, G. Rechavi, N. Amariglio, Israel CORRELATION BETWEEN DIFFERENT CHROMOSOME ALTERATIONS IN MULTIPLE MYELOMA: COMBINED ANALYSIS OF MORPHOLOGY AND FISH ON THE SINGLE CELL LEVEL

91 Poster Session B – Dan (continued)

PB-188 Y. Tzuman, S. Sapoznik, Israel, D. Granot, USA, N. Nevo, M. Neeman, Israel HORMONAL REGULATION OF HYALURONAN SYNTHASE AND ITS EFFECT ON ADHESION IN HUMAN EPITHELIAL OVARIAN CARCINOMA METASTASIS

PB-189 R. Uzana, A. Machlenkin, S. Frankenburg, L. Eisenbach, J. Pitkovski, R. Gorodetsky, A. Nissan, T. Peretz, E. Yefenof, M. Lotem, Israel MEMBRANE CAPTURE BY TUMOR-REACTIVE T CELLS: A NEW APROACH FOR IDENTIFICATION OF FUNCTIONAL CYTOTOXIC T LYMPHOCYTES

PB-190 N. Weinberg, A. Klochendler, M. Brandeis, A. Eden, Y. Dor, Israel A LIVE REPORTER FOR PANCREATIC BETA CELL PROLIFERATION

PB-191 S. Yaari-Stark, Y. Kloog, Israel INDUCE STRESS RESPONSE IN HUMAN NEUROBLASTOMA CELLS PROMOTES CELL DEATH

PB-192 I. Zafir-Lavie, Israel GLIOBLASTOMA MULTIFORME MICROENVIRONMENT: IMMUNE RESPONSE AND ANTIBODY MEDIATED TARGETING

PB-193 A. Ziv-Av, D. Taller, M. Atia, Israel, C. Xiang, USA, G. Kazimirsky, R. Sarid, C. Brodie, Israel RELATED TO TESTIS-SPECIFIC, VESPID, AND PATHOGENESIS PROTEIN 1 (RTVP-1) IS REGULATED BY PROTEIN KINASE C AND SERUM RESPONSE FACTOR IN GLIOMA CELLS

PB-194 N.S. Zuckerman, Israel, K. McCann, C.H. Ottensmeier, UK, R.S. Abraham, USA, M. Barak, G. Shahaf, H. Edelman, Israel, D. Dunn-Walters, F.K. Stevenson, UK, R. Mehr, Israel LINEAGE TREE ANALYSIS AND THE DYNAMICS OF FL AND DLBCL

General subjects II

PB-195 L. Levi, I. Pekarski, B. Sivan, E. Lubzens, Israel REVEALING GENES INVOLVED IN RETINAL SYNTHESIS IN THE FISH LIVER, USING GENE EXPRESSION MICROARRAY

PB-196 S. Leviatan, N. Nelson, Israel A NOVEL METHOD FOR THE OVEREXPRESSION OF MEMBRANE PROTEINS IN E. COLI

PB-197 G. Levy, D. Goldberg, K. Jackson, Y. Gothlif, G. Degani, Israel EFFECT OF GnRH AND GHRH ON PITUITARY GENE EXPRESSION OF THE BLUE GOURAMI MALES

PB-198 G. Linshiz, T. Ben Yehezkel, U. Shabi, S. Kaplan, R. Adar, E. Shapiro, Israel ON THE ROAD TO GENE SYNTHESIS MACHINES

PB-199 M. Lugassi Ben-Hamo, M. Zaccai, Israel CHARACTERIZATION OF FLORAL TRANSITION IN LISIANTHUS (EUSTOMA GRANDIFLORUM)

PB-200 M. Mandel, A. Achiron, Israel, T. Barliya, USA, T. Tuller, T. Ben-Aharon, G. Rechavi, N. Amariglio, R. Loewenthal, I.R. Cohen, Israel OLIGOCLONAL COMBINATIONS THAT FORM AUTOREACTIVE T-CELL LINES IN PROBABLE MULTIPLE SCLEROSIS PATIENTS DISPLAY SKEWED "CLONAL CLUSTER SIGNATURES"

PB-201 A. McGregor, M. Klartag, N. Adir, Israel PIECING TOGETHER THE PHYCOBILISOME

PB-202 A. Meir Ben Efraim, E. Podoly, Israel, H.R. Nordlund, M.S. Kulomaa, Finland, E.A. Bayer, M. Wilchek, O. Livnah, Israel STRUCTURAL INSIGHTS INTO RHIZAVIDIN: THE FIRST DIMERIC MEMBER OF THE AVIDIN FAMILY

PB-203 S. Meirovitch, S. Lapidot, S. Ittah, U. Gat, O. Shoseyov, Israel PROTEIN ENGINEERING OF CELLULOSE – SPIDER SILK COMPOSITE

92 Poster Session B – Dan (continued)

PB-204 N. Mokhir, M. Mandel, A. Achiron, T. Ben-Aharon, I.R. Cohen, B. Sredni, G. Lavie, Israel UNIQUE EXPRESSION PATTERNS OF MEMORY DETERMINANTS AND ADHESION MOLECULES ON T CELLS FROM LINES DERIVED FROM PROBABLE MULTIPLE SCLEROSIS PATIENTS

PB-205 M. Moshe, E. Banin, Israel CURCUMIN A NATURAL ANTIBIOFILM AGENT

PB-206 N. Movshovich, I. Shumacher, V. Fridman, B. Katz, L. Gheber, Israel MID-ANAPHASE PAUSE IN S.CEREVISIAE CELLS

PB-207 I. Noach, F. Frolow, R. Lamed, O. Alber, L.J.W. Shimon, E.A. Bayer, Israel LINKER FLEXIBILITY AND MODULAR ARRANGEMENT REVEALED FROM THE CRYSTAL STRUCTURES OF CELLULOSOMAL ACETIVIBRIO CELLULOLYTICUS TYPE-II COHESIN MODULES

PB-208 N. Diamant, Israel, N.E. Geacintov, USA, Z. Livneh, Israel CELL-CYCLE REGULATION OF TRANSLESION DNA SYNTHESIS IN MAMMALIAN CELLS

PB-209 O. Ohayon, N. Mawasi, A. Pevzner, A. Tryvitz, T. Gildor, M. Pines, M. Paizi, G. Spira, Israel THE EXPRESSION OF HEPARANASE AND VEGF ARE LINKED DURING LIVER REMODELING

PB-210 Y. Hasin, T. Olender, M. Khen, Israel, J. Korbel, P. Kim, M. Gerstein, USA, D. Lancet, Israel GENOMIC VARIABILITY IN OLFACTORY RECEPTORS: NATURAL KNOCKOUTS AND COPY NUMBER VARIATION

PB-211 Withdrawn

PB-212 A. Parnas, A.L. Bonshtien, A. Niv, A. Azem, C. Weiss, Israel FUNCTIONAL AND NON-FUNCTIONAL INTERACTIONS BETWEEN MITOCHONDRIAL AND CHLOROPLAST CHAPERONIN SYSTEMS

PB-213 O. Parnas, M. Kupiec, Israel Elg1, A NOVEL MAINTAINER OF GENOMIC STABILITY, INTERACTS WITH SUMO AND PCNA

PB-214 M. Parter, N. Kashtan, U. Alon, Israel THE EVOLUTION OF FACILITATED PHENOTYPIC VARIATION IN SIMPLE MODEL SYSTEM

PB-215 A. Pechorsky, Y. Nitzan, Z. Lazarovich, Israel CALCIUM INFLUENCE ON BIOFILM FORMATION BY COAGULASE NEGATIVE STAPHYLOCOCCI ON INTRAVASCULAR CATHETERS

PB-216 S. Qu, B.I. Kanner, Israel GLUTAMATE INDUCES STRUCTURAL REARRANGEMENTS AT THE EXTRACELLULAR ENTRANCE OF THE TRANSLOCATION PATHWAY OF THE GLIAL GLUTAMATE TRANSPORTER GLT-1

PB-217 A. Raz, R.A. Stern, S. Shafir, D. Bercovich, M. Goldway, Israel SFB-BASED S-HAPLOTYPING OF APRICOT (PRUNUS ARMANIACA) WITH DHPLC

PB-218 A. Reich, E. Monsonego-Ornan, Israel THE EFFECT OF MECHANICAL LOAD ON THE IHH-PTHrP FEEDBACK LOOP IN GROWTH PLATE CHONDROCYTES

PB-219 Y. Reizel, D. Galiani, E. Gershon, A. Hourovitz, N. Dekel, Israel STEAP AND FAR1, NEW POTENTIAL REGULATORS OF THE OVULATORY PROCESS

PB-220 L.A. Rosenberg Belmaker, F. Libersat, Israel OCTOPAMINE PARTIALLY RESTORES WALKING IN HYPOKINETIC COCKROACHES STUNG BY THE PARASITOID WASP AMPULEX COMPRESSA

PB-221 A. Rosenberg, B.I. Kanner, Israel THE SUBSTRATES OF THE GABA TRANSPORTER GAT-1 INDUCE STRUCTURAL REARRANGMENTS AT THE INTERFACE OF TRANSMEMBRANE DOMAINS 1 AND 6

93 Poster Session B – Dan (continued)

PB-222 L. Rubinovich, D. Weiss, Israel GAST-LIKE PROTEINS: POSSIBLE ROLES IN REDOX REGULATION AND PLANT DEVELOPMENT

PB-223 H. Saida, R. Gersner, B. Sredni, A. Zangen, Israel HE EFFECT OF AS101 IN A CRONIC MILD STRESS MODEL OF EPRESSIVE BEHAVIOR

PB-224 Withdrawn

PB-225 A.F. Savulescu, H. Shorer, M.H. Glickman, A. Harel, Israel NUCLEOCYTOPLASMIC TRANSPORT OF THE PROTEASOME IN IN VITRO RECONSTITUTED XENOPUS NUCLEI

PB-226 D. Schatz, E. Shimoni, E. Klein, O. Yeger, Y. Friedman, R. Schwarz, Israel MUTATIONS IN SECRETION SYSTEMS LEAD TO BIOFILM FORMATION IN A PLANKTONIC CYANOBACTERIUM

PB-227 A. Schauder, Z. Malik, Israel THE REGULATORY TRIANGLE HEME-PROTEASOME-PBGD CONTROLS HEME AND GLOBIN SYNTHESIS DURING ERYTHROLEUKEMIC DIFFERENTIATION

PB-228 E. Schnur, D. Gordon, M. Gurevitz, J. Anglister, Israel NMR ANALYSIS OF THE BINDING SITE OF A HIGHLY INSECTICIDAL SCORPION ALPHA-TOXIN TO A PEPTIDE DERIVED FROM A SODIUM CHANNEL

PB-229 N. Schreiber, N. Gierlinger, I. Burgert, P. Fratzl, N. Putz, Germany ROOT CONTRACTION IN RED CLOVER (TRIFOLIUM PRATENSE)

PB-230 Y. Olswang-Kutz, Y. Gertel, S. Benjamin, E. Arama, Israel, H. Steller, USA, M. Horowitz, D. Segal, Israel THE DROSOPHILA Past1 CONTROLS GERM LINE DEVELOPMENT AND IS ESSENTIAL FOR SURVIVAL OF THE ADULT FLY

PB-231 E. Segal, G. Lehmann, R. Tacutu, Israel, K. Muradian, Ukraine, V. Fraifeld, Israel MAMMALIAN LONGEVITY IS ASSOCIATED WITH THE LENGTH OF D-LOOP AND THE NUMBER OF DIRECT REPEATS IN MITOCHONDRIAL DNA

PB-232 Z. Sevilya, Z. Livneh, T. Paz-Elizur, Israel DEVELOPMENT OF AN EPIDEMIOLOGY-GRADE ENZYMATIC DNA REPAIR ASSAY FOR THE APURINIC/APYRIMIDINIC ENDONUCLEASE (APE) ACTIVITY IN HUMAN BLOOD CELLS

PB-233 S. Shachar, Israel, N.E. Geacintov, USA, T. Carell, Germany, R.D. Wood, USA, Z. Livneh, Israel THE ROLE OF DNA POLYMERASE ZETA IN ERROR-PRONE DNA REPAIR IN MAMMALIAN CELLS

PB-234 Y. Shahar-Pomerantz, E. Gershon, D. Galiani, A. Hourvitz, N. Dekel, Israel EXPRESSION OF Magoh IN MAMMALIAN OVARY: CHARACTERIZATION,REGULATION AND FUNCTION

PB-235 R. Sharir, E. Mendelson, L. Shulman, D. Soffer, A. Avni, Israel TOWARDS GENERATING AN EDIBLE VACCINE AGAINST POLIO VIRUS

PB-236 A. Shiloah, I. Eshkar, Israel, R.L. Proi, USA, E. Zelzer, Israel S1P1 PLAY A KEY ROLE IN THE REGULATION OF ANGIOGENESIS DURING EARLY LIMB DEVELOPMENT

PB-237 S. Shimron, V. Yashunsky, V. Lirtsman, D. Davidov, B. Aroeti, Israel FOURIER-TRANSFORM-INFRARED SURFACE PLASMON RESONANCE AS A NOVEL TOOL FOR REAL-TIME AND LABEL-FREE BIOSENSING OF LIGAND INTERNALIZATION VIA CLATHRIN- COATED PITS

PB-238 K. Shkolnik, S. Ben-Dor, D. Galiani, N. Nevo, A. Hourvitz, N. Dekel, Israel MOLECULAR CHARACTERIZATION AND BIOINFORMATIC ANALYSIS OF Ncoa7B, A NOVEL OVULATION-ASSOCIATED AND REPRODUCTION SYSTEM-SPECIFIC Ncoa7 ISOFORM

94 Poster Session B – Dan (continued)

PB-239 M. Shmueli, Y. Amir, E. Gazit, D. Segal, Israel TOWARDS RESTORING FOLDING AND FUNCTION OF MUTANT VON-HIPPEL LINDAU TUMOR SUPRESSOR PROTEIN IN DROSOPHILA

PB-240 M. Shnit-Orland, A. Kushmaro, Israel CORAL MUCUS AS A SOURCE OF BACTERIA WITH ANTIMICROBIAL ACTIVITY

PB-241 S. Shulami, N. Lavid, E. Naveh, O. Tabachnikov, Y. Shoham, Israel THE ARABINAN-UTILIZATION ELEMENTS IN GEOBACILLUS STEAROTHERMOPHILUS: REGULATION AND FUNCTION ANALYSIS

PB-242 S. Simsa, E. Monsonego Ornan, Israel THE EFFECT OF INTERLEUKIN-1-BETA ON CHONDROGENESIS AND SIGNALING PATHWAYS IN CHONDROCYTES

PB-243 M. Slutzki, A. Karpol, A. Demishtein, L. Kantorovich, E.A. Bayer, Israel MANIPULATIONS OF THE RUMINOCOCCUS FLAVEFACIENS ScaA DOCKERIN TO STUDY ITS STRUCTURE AND FUNCTION

PB-244 T. Sobel, M. Kupiec, Israel REGULATION OF TELOMERE LENGTH IN S. CEREVISIAE BY ELG1

PB-245 R. Tacutu, E. Segal, G. Lehmann, V. Fraifeld, Israel REPEAT SURVEYOR – A TOOL FOR VIZUALIZATION AND ANALYSIS OF MITOCHONDRIAL DNA REPEATS

PB-246 H. Tal, S. Lev, B.A. Horwitz, Israel ACTIVATION OF PATHOGENICITY MAP KINASE IN COCHLIOBOLUS HETEROSTROPHUS: DIFFERENT LEVELS OF REGULATION

PB-247 N. Tejman-Yarden, A. Wolff, L. Schipunov, L. Shevitz, I. Belmaker, I. Nissan, Israel THE MICROBIAL COMPLEXITY OF COMMERCIAL POWDERED INFANT FORMULAE

PB-248 N. Trushina, E. Pardovitz-Kedmi, A. Igbaria, S. Lev, B.A. Horwitz, Israel REGULATION OF A HIGH-AFFINITY TRANSPORTER GENE OF TRICHODERMA VIRENS

PB-249 A. Tryvitz, O. Ohayon, M. Paizi, G. Spira, Israel EXPRESSION OF VEGF AND HEPARANASE IN CO-CULTURES OF HEPATOCYTES AND HEPATIC STELLATE CELLS ARE LINKED

PB-250 R. Tuchman, E. Banin, Israel INFLUENCE OF IRON-REGULATED RHAMNOLIPID PRODUCTION ON SURFACE MOTILITY AND BIOFILM FORMATION BY PSEUDOMONAS AERUGINOSA

PB-251 N. Tzarum, R. Diskin, M. Avitzour, D. Engelberg, O. Livnah, Israel SELECTED MUTATIONS IN P38 alpha ON THE ALTERNATIVE ACTIVATION SITE, Y323, DISPLAY INTRINSIC ACTIVITY POSSIBLY MIMICKING THE ACTIVE CONFORMATION

PB-252 A. Vitlin, A.L. Bonshtien, C. Weiss, A. Niv, A. Azem, Israel THE FUNCTION OF RECONSTITUTED CHLOROPLAST CHAPERONINS FROM A. THALIANA

PB-253 C. Walzer, D. Fass, Israel POST-TRANSLATIONAL MODIFICATIONS ON AN ANTIFREEZE PROTEIN TO CREATE A VARIETY OF POTENTIAL INORGANIC SURFACE BINDING PROTEINS

PB-254 A. Wellner, M.E. Lurie, U. Gophna, Israel COMPLEXITY, CONNECTIVITY AND THE FATE OF LATERALLY ACQUIRED GENES

PB-255 Withdrawn

PB-256 E. Wineman, T. Weiss, N. Farzam, N. Savion, N.I. Smorodinsky, E. Kessler, Israel MONOCLONAL ANTIBODIES AS TOOLS IN STRUCTURE-FUNCTION ANALYSIS OF PROCOLLAGEN C-PROTEINASE ENHANCER-1 (PCPE-1)

95 Poster Session B – Dan (continued)

PB-257 S.E. Winograd-Katz, S. Itzkovitz, Z. Kam, B. Geiger, Israel MULTIPARAMETRIC ANALYSIS OF THE MODULATION OF CELL ADHESION AND SHAPE BY RNAI-MEDIATED GENE KNOCKDOWN

PB-258 H. Yanai, A. Budovsky, A. Abramovich, R. Tacutu, V. Fraifeld, Israel HIGH EVOLUTIONARY CONSERVATION OF LONGEVITY-ASSOCIATED GENES

PB-259 A. Yeheskel, Israel, T. Haliloglu, Turkey, N. Ben-Tal, Israel COMPUTATIONAL ANALYSIS OF VOLTAGE-GATED POTASSIUM-CHANNELS

PB-260 S. Yerushalmi, R.M. Green, Israel THE ADAPTIVE SIGNIFICANCE OF CIRCADIAN RHYTHMS IN PLANTS

PB-261 N. Yissachar, H. Salem, B. Motro, Israel Nek7, A NOVEL CENTROSOMAL KINASE, REGULATE MITOTIC PROGRESSION AND CYTOKINESIS COMPLETION

PB-262 T. Zeev-Ben-Mordehai, A. Paz, Israel, E. Mylonas, Germany, L. Toker, Israel, D. Svergun, Germany, I. Silman, J.L. Sussman, Israel STRUCTURAL AND BIOPHYSICAL CHARACTERIZATION OF AMALGAM, A DROSOPHILA NEURONAL ADHESION PROTEIN

PB-263 Y. Zilberman, Israel, C. Ballestrem, UK, L. Carramusa, Germany, A. Bershadsky, Israel mDia1 FORMIN AND DYNACTIN COMPLEX AS A POSSIBLE DYNAMIC LINK BETWEEN ACTIN AND MICROTUBULES

PB-264 Withdrawn

PB-265 O. Ziv, Israel, N.E. Geacintov, USA, T. Carell, Germany, Z. Livneh, Israel KINETICS AND FIDELITY OF TRANSLESION DNA SYNTHESIS IN HUMAN CELLS

PB-266 K. Zohary, L. Airapetov, A. Azem, Israel MITOCHONDRIAL PROTEIN IMPORT: A STRUCTURE-FUNCTION ANALYSIS OF THE TIM23 PROTEIN

Marine and terrestrial biodiversity

PB-267 M. Halpern, D. Raats, S. Lev-Yadun, Israel PLANT BIOLOGICAL WARFARE: THORNS INJECT PATHOGENIC MICROORGANISMS INTO HERBIVORES

PB-268 M. Harel, D. Schatz, S. Carmeli, A. Sukenik, A. Kaplan, Israel THE BIOLOGICAL ROLE OF SECONDARY METABOLITES IN THE TOXIC MICROCYSTIS POPULATION

PB-269 D. Ionescu, A. Oren, S. Penno, A.F. Post, M. Chernihovsky, L. Hazanov, Israel MARINE ARCHAEA IN COASTAL WATERS IN ISRAEL

PB-270 A. Or, O. Gophna, Israel PROFILING THE MICROBIAL COMMUNITY OF THE YARQON RIVER

PB-271 N. Qvit-Raz, O. Finkel, E. Jurkevitch, S. Belkin, Israel BIODIVERSITY OF THE MICROBIAL COMMUNITY OF THE TAMARIX PHYLLOSPHERE

PB-272 N. Siboni, E. Kramarsky-Winter, Y. Loya, A. Sivan, A. Kushmaro, Israel COMPARISON STUDY OF AGGREGATE-LIKE MICROORGANISMS ON CORALS FROM EILAT AND HERON ISLAND, GREAT BARRIER REEF

96 Poster Session B – Dan (continued)

Metagenomic and functional genomic of microorganisms

PB-273 S. Neder Lavon, N. Gollop, V. Zakin, C. Songbi, Israel DO ALL BACRERIOCINS ARE PORE FORMERS?

PB-274 S. Reikhav, A. Levy, N. Barkai, Israel EXPLORING THE GENETIC BASIS OF HYBRID VIGOR IN INTER-SPECIFIC YEAST HYBRIDS

PB-275 S. Tzahor, D. Man-Aharonovich, O. Beja, Y. Mandel-Gutfreund, Israel CLASSIFYING AND PREDICTING PHOTOSYNTHETIC GENE FRAGMENTS FROM THE ENVIRONMENT

Signal transduction

PB-276 T. Almog, S. Lazar, N. Reiss, N. Etkovitz, N. Rahamim, M. Dobkin-Bekman, R. Rotem, M. Kalina, H. Breitbart, R. Seger, Z. Naor, Israel NOVEL ROLES FOR p38MAPK AND ERK1/2 IN HUMAN SPERMATOZOA: REGULATION OF FLAGELLAR MOTILITY, HYPERACTIVATION AND ACROSOME REACTION

PB-277 J. Alter, E. Bengal, Israel THE ROLE OF JNK SIGNALING IN TNFalpha- MEDIATED INHIBITION OF MYOBLAST DIFFERENTIATION

PB-278 O. Ariel Cohen, N. Hollander, Israel DIFFERENTIAL SIGNALING BY THE GPI-ANCHORED AND TRANSMEMBRANE ISOFORMS OF CD58

PB-279 M. Avitzour, R. Diskin, B. Raboy, N. Askari, D. Engelberg, O. Livnah, Israel RATIONAL DESIGN OF ALL INTRINSICALLY ACTIVE p38 MAP KINASES

PB-280 M. Avner, Y. Litvak, T. Danieli, Z. Selinger, Israel THE HIGHLY CONSERVED LEUCINES OF BACTIRIAL GAPs AND THEIR ROLE IN CONFORMATION STABILITY

PB-281 D. Avni, M. Goldsmith, G. Levy-Rimler, M. Levi, T. Zor, Israel SIMULTANEOUS TNF-ALPHA SUPPRESION AND IL-10 INDUCTION IN ACTIVATED MACROPHAGES BY A CERAMIDE-1-PHOSPHATE ANALOG, PCERA-1

PB-282 M. Avram, X-H. Ma, M. Cohen-Armon, N. Moran, Israel DOES PLASMA MEMBRANE POTENTIAL REGULATE THE PLANT PARP VIA THE PHOSPHOINOSITIDES PATHWAY?

PB-283 M. Bar, M. Aharon, B. Rotblat, S. Benjamin, M. Horowitz, A. Avni, Israel FUNCTION AND CHARACTERIZATION OF PLANT EH DOMAIN PROTEINS

PB-284 Y. Bar Lev-Abargil, R. Leibowitz-Amit, G. Tsarfaty, G.M. Yerushalmi, G. Stein, J. Horev, I. Tsarfaty, Israel Mimp, A MITOCHONDRIAL CARRIER HOMOLOGUE, INHIBITS Met-HGF/SF-INDUCED SCATTERING AND TUMORIGENICITY BY ALTERING Met-HGF/SF SIGNALING PATHWAYS

PB-285 D. Beach, R. Gonen, Y. Bogin, D. Yablonski, Israel DUAL ROLE OF SLP-76 IN MEDIATING T CELL RECEPTOR-INDUCED ACTIVATION OF PHOSPHOLIPASE C-GAMMA1

PB-286 D. Ben David, A.Z. Reznick, E. Livne, Israel INFLAMMATION INDUCED NF-kB ACTIVATION UP-REGULATES MATRIX METALLOPROTEINASE -2,9 SYNTHESIS IN BONE MARROW-DERIVED OSTEOPROGENITORS

PB-287 T. Bershitsky, S. Daniliuc, A. Aronheim, Israel A NOVEL JNK SCAFFOLD PROTEIN INVOLVED IN STRESS GRANULE FORMATION

PB-288 J. Biran, S. Ben-Dor, B. Levavi-Sivan, Israel MOLECULAR IDENTIFICATION AND FUNCTIONAL CHARACTERIZATION OF THE KISSPEPTIN/GPR54 SYSTEM IN LOWER-VERTEBRATES

97 Poster Session B – Dan (continued)

PB-289 R. Blecher-Gonen, D. Yablonski, Israel TCR-INDUCED SERINE-PHOSPHORYLATION OF THE ADAPTOR PROTEIN SLP-76

PB-290 Y. Bogin, D. Yablonski, Israel SLP-76 MEDIATES AND MAINTAINS ACTIVATION OF THE TEC FAMILY KINASE, ITK, VIA THEIR TCR-INDUCED ASSOCIATION

PB-291 M.C. Brunner, B. Geiger, Israel MECHANISMS UNDERLYING THE REGULATION OF FOCAL ADHESION FORMATION BY THE TYROSINE KINASE pp60src

PB-292 D. Chorev, N. Dym, I. Ziv, D. Ron, Israel IDENTIFICATION OF NOVEL hSEF-a BINDING PARTNERS AND PHOSPHORYLATION SITES

PB-293 C. Cohen-Saidon, A.A. Cohen, A. Sigal, U. Alon, Israel DYNAMICS OF MAPK SIGNALING IN INDIVIDUAL CELLS

PB-294 A. Di Segni, K. Farin, R. Pinkas-Kramarski, Israel IDENTIFICATION OF NUCLEOLIN AS A NEW ErbB RECEPTOR INTERACTING PROTEIN

PB-295 A. Dreazen, M. Katz, I. Ruvinsky, A. Saada-Reisch, N.C. Friedman, G. Zimmerman, O. Meyuhas, Israel PHOSPHORYLATION OF RIBOSOMAL PROTEIN S6 IS A DETERMINANT OF THE SIZE AND FUNCTION OF BETA CELLS AND MYOBLASTS

PB-296 E. Elyada, G. Brachya, A. Pribluda, G. Cojocaro, Y. Morgenstern, S. Jung, R. Haffner, M. Oren, E. Pikarsky, Y. Ben-Neriah, Israel CKI-ALPHA SECURES INTESTINAL HOMEOSTASIS BY BALANCING THE PROTEIN LEVELS OF BETA-CATENIN AND p53

PB-297 N. Etkovitz, I. Tirosh, R. Chazan, Y. Jaldety, S. Rubinstein, H. Breitbart, Israel TRANSACTIVATOIN OF SPERM EGFR BY GPCR IS MEDIATED BY PROTEIN KINASE A

PB-298 Y. Fuchs, L. Baruch, M. Machluf, D. Ron, Israel THE ROLE OF Sef DURING WOUND REPAIR AND THE MECHANISM REGULATING IT'S EXPRESSION

PB-299 R. Hayouka, D. Engelberg, O. Livnah, Israel DESIGN OF INTRINSICALLY ACTIVE MUTANTS OF HUMAN JNK MAP KINASES

PB-300 S. Kahana, Israel, P. Kainth, H. Sassi, Canada, Y. Kassir, Israel, B. Andrews, Canada HIGH-THROUGHPUT IDENTIFICATION OF GENES REGULATING THE TRANSCRIPTION OF IME1

PB-301 E. Kalo, Y. Buganim, K.E. Shapira, E. Barnatan, H. Besserglick-Solomon,N. Goldfinger, L. Weisz, P. Stambolsky, Y.I. Henis, V. Rotter, Israel MUTANT p53 ATTENUATES THE SMAD-DEPENDENT TGF-beta1 SIGNALING PATHWAY BY REPRESSING THE EXPRESSION OF TGF-beta RECEPTOR TYPE II

PB-302 V. Kaplan-Cohen, I. Doweck, I. Naroditsky, N. Ilan, I. Vlodavsky, Israel HEPARANASE INDUCES Src-DEPENDENT EGFR PHOSPHORYLATION

PB-303 M. Kofer, I. Gottfried, Y. Kloog, U. Ashery, Israel IDENTIFICATION OF RASOSOMES 'HOT-SPOTS' IN THE PLASMA MEMBRANE OF LIVE CELLS

PB-304 K. Korotayev, Israel, M. Chaussepied, France, D. Ginsberg, Israel ERK ACTIVATION IS REGULATED BY E2F1 AND IS ESSENTIAL FOR E2F1-INDUCED S PHASE ENTRY

PB-305 D. Laor, R. Weisman, M. Kupiec, Israel THE MODE OF ACTION OF THE ANTICANCEROUS DRUG RAPAMYCIN IN FISSION YEAST

PB-306 G. Lazer, L. Pe'er, V. Schapira, Israel, S. Richard, Canada, S. Katzav, Israel THE ASSOCIATION OF Sam68 WITH Vav1 CONTRIBUTES TO TUMORIGENESIS

98 Poster Session B – Dan (continued)

PB-307 D. Levy, Y. Adamovich, N. Reuven, Y. Shaul, Israel DNA-DAMAGE SIGNALING AND APOPTOSIS: A NEW PATHWAY OF DECISION MAKING

PB-308 R. Levy, N. Hadad, M. Karter, M. Eisenstein, D. Gitler, Israel A UNIQUE HYDROPHOBIC INTERACTION BETWEEN CYTOSOLIC PHOSPHOLIPASE A2 AND THE ASSEMBLED NADPH OXIDASE – TARGETING TO THE PLASMA MEMBRANES

PB-309 X-H. Ma, O. Shor, S. Diminshtein, L. Yu, Israel, Y.J. Im, I. Perera, W.F. Boss, USA, N. Moran, Israel PHOSPHOINOSITIDES REGULATE A PLANT K+EFFLUX CHANNEL IN TOBACCO CULTURED CELLS

PB-310 I. Maayan, C. Levenberg, D. Engelberg, Israel HOG1 IS NOT REQUIRED FOR YEAST SURVIVAL UNDER OSMOTIC STRESS

PB-311 I. Maymon, D. Weiss, Israel SPIDNLY AN O-GlcNAC TRANSFERASE: INTRACELLULAR SITE OF ACTION IN THE REGULATION OF GIBBERELLIN AND CYTOKININ RESPONSE

PB-312 Y. Mosesson, L. Schley, Y. Yarden, Israel Lst2: A NOVEL REGULATOR OF EGF RECEPTOR DOWNREGULATION

PB-313 M. Schonbrun, R. Weisman, M. Kupiec, Israel TORC2 IS REQUIRED FOR SURVIVAL AFTER DNA DAMAGE IN SCHIZOSACCHAROMYCES POMBE

PB-314 M. Levi, Israel/France, H. Oppenheim, R. Shalgi, Israel, B. Maro, France CHARACTERIZATION OF Fyn DURING MEIOSIS OF MOUSE OOCYTES

PB-315 M. Sharfman, S. Schuster, A. Avni, Israel IDENTIFYING COMPONENTS INVOLVED IN THE LeEIX-EIX MEDIATED HR

PB-316 O. Ernst, M. Goldsmith, D. Avni, G. Levy-Rimler, T. Zor, Israel SYNERGISTIC INDUCTION OF IL-10 BY A TLR AGONIST AND A PHOSPHOLIPID-LIKE MOLECULE

PB-317 M. Shohat, D. Ben Meir, S. Lavi, Israel PROTEIN PHOSPHATASE 2CALPHA PLAYS A ROLE IN THE DIFFERENTIATION AND SURVIVAL PROCESSES OF PC6-3 CELLS

PB-318 M. Dobkin-Bekman, L. Sviridonov, B. Shterntal, C. Brodie, R. Seger, Z. Naor, Israel DIFFERENTIAL ROLE OF PKC ISOFORMS IN GNRH ACTIVATION OF EXTRACELLULAR SIGNAL- REGULATED KINASE (ERK) AND JUN N-TERMINAL KINASE (JNK)

PB-319 E. Starosvetsky, D. Yablonski, Israel A GENETIC ANALYSIS OF THE SIGNALING PATHWAYS THAT MEDIATE CHEMOKINE-INDUCED MIGRATION IN T CELLS

PB-320 Z. Granot, A. Swisa, Israel, N. Bardeesy, USA, Y. Dor, Israel CONTROL OF PANCREATIC BETA CELL POLARITY, SIZE AND FUNCTION BY LKB1

PB-321 A. Tadmor, N. Nevo, D. Galiani, N. Dekel, Israel ROLE OF CONNEXINS IN OOCYTE MATURATION

PB-322 G. Tarcic, I. Amit, T. Shay, M. Katz, J. Jacob-Hirsch, N. Amariglio, G. Rechavi, E. Donany, Y. Yarden, Israel FROM INPUT TO OUTPUT: EGF INDUCED CELLULAR PROGRAM IN MAMMARY CELL MIGRATION

PB-323 N. Volinsky, A. Gantman, D. Yablonski, Israel A PAK- AND PIX-DEPENDENT BRANCH OF THE SDF-1alphaׁSIGNALING PATHWAY MEDIATES T CELL CHEMOTAXIS ACROSS RESTRICTIVE BARRIERS

PB-324 Y. Wainberg, D. Weiss, Israel SPY, AN O-GlcNAC transferase IS REQUIRED FOR THE CYTOSOLIC LOCALIZATION OF THE PHOSPHOTRANSFER PROTEIN AHP AND FOR NORMAL CYTOKININ RESPONSES

99 Poster Session B – Dan (continued)

PB-325 R. Weisman, M. Schonbrun, D. Laor, M. Kupiec, Israel NOVEL ROLES FOR TOR (TARTGET OF RAPAMYCIN) PROTEINS IN REGULATING GROWTH AND RESPONSE TO DNA DAMAGE

PB-326 S. Weiss, D. Dadon, B. Minke, Israel CALPHOTIN REGULATION OF THE LIGHT RESPONSE IN DROSOPHILA PHOTOTRANSDUCTION

PB-327 A. Gantman, N. Volinsky, E. Suss-Toby, D. Yablonski, Israel PROBING THE ROLE OF p21-ACTIVATED KINASE IN T CELL MIGRATION AND POLARIZATION

PB-328 C. Ziv, R. Gorovits, O. Yarden, Israel CRE1, A REGULATOR OF CATABOLITE REPRESSION IS INVOLVED IN DETERMINING PKA- DEPENDENT POLARITY OF N. CRASSA

PB-329 Y. Zwang, Y. Yarden, Israel STRESS-INDUCED, p38-MEDIATED EGFR PHOSPHORYLATION AND INTERNALIZATION

100 17:30 – 20:00 Poster Session B Zone 3, Royal Beach

Calcium channels and calcium modulated channels

PB-330 A. Ben Moha, S. Oz, J. Hirsh, L. Almagor, N. Dascal, Israel N–TERMINUS BINDING SITES OF CYTOPLASMIC REGULATORY PROTEINS OF THE Cav1.2 CHANNEL

PB-331 L. Buzaglo, O. Beharier, S. Kolt, A. Moran, Israel FLUORESCENTLY TAGGED ZnT-1 AS A TOOL FOR LOCALIZATION AND FUNCTION

PB-332 S. Kolt, O. Beharier, U. Goshen, L. Buzaglo, L. Shaltiel, S. Anavi-Goffer, Y. Etzion, A. Katz, D. Gitler, A. Moran, Israel THE INHIBITION OF THE L-TYPE CALCIUM CHANNEL (LTCC) BY ZnT-1; A MOLECULAR MECHANISM

PB-333 M. Mor, O. Beharier, Y. Etzion, A. Kats, A. Moran, Israel REDUCED SURFACE EXPRESSION OF L-TYPE CALCIUM CHANNELS IN RAPIDLY PACED CARDIOMYOCYTES; A NEW MECHANISM OF ATRIAL ELECTRICAL REMODELING?

PB-334 S. Oz, N. Dascal, Israel CaBP1 REGULATES INACTIVATION OF BOTH Ca AND Ba CURRENTS THROUGH Ca(V)1.2 (L-TYPE) CALCIUM CHANNELS

PB-335 I. Tselnicker, N. Dascal, Israel THE EFFECT OF G PROTEIN ALPHA SUBUNIT ON G PROTEIN BETAGAMMA MEDIATED MODULATION OF N-TYPE CALCIUM CHANNEL

Innate immunity and immune surveillance

PB-336 H. Achdout, Israel, S. Nedvetzki, C.R. Almeida, UK, T. Gonen-Gross, Israel, D.M. Davis, UK, O. Mandelboim, Israel INFLUENZA VIRUS AUGMENTS NK CELL INHIBITION THROUGH THE REORGANIZATION OF MHC CLASS I PROTEINS

PB-337 L. Bar-on, T. Birnberg, D. Brockschnieder, Israel, B. Reizis, USA, S. Jung, Israel CONSTITUTIVE DENDRITIC CELL ABLATION IS COMPATIBLE WITH NORMAL DEVELOPMENT, BUT CAUSES PROGRESSIVE MYELOID PROLIFERATIVE DISORDER

PB-338 T. Birnberg, V. Plaks, T. Berkutzki, V. Kalchenko, Israel, G. Mor, USA, N. Dekel, M. Neeman, S. Jung, Israel UTERINE DENDRITIC CELLS ARE CRUCIAL FOR DECIDUA FORMATION DURING EMBRYO IMPLANTATION

PB-339 S. Bransburg-Zabary, A. Madi, Israel, I. Hecht, USA, A. Pick, I. Baruchi, Israel, Y. Merbl, USA, M. Zucker-Toledano, Israel, A.I. Tauber, USA, I.R. Cohen, E. Ben-Jacob, Israel IMMUNE HOLOGRAPHY: SYSTEM-LEVEL ANALYSIS OF IMMUNOLOGICAL STATES

PB-340 S. Dotan, Y. Krelin, E. Voronov, M. Elkabets, Israel, C.A. Dinarello, USA, R.N. Apte, Israel THE ROLE OF IL-1 BETA IN CHEMICAL - INDUCED CARCINOGENESIS AND TUMOR PROGRESSION

PB-341 R. Gruda, O. Mandelboim, Israel INTRACELLULAR CYSTEINE RESIDUES IN THE TAIL OF MHC CLASS I PROTEINS ARE CRUCIAL FOR EXTRACELLULAR RECOGNITION BY LIR1

PB-342 O. Hershkovitz, A. Zilka, Israel, M. Jacobs, UK, A. Porgador, Israel INTERACTION BETWEEN NK CELLS AND FLAVIVIRUSES

PB-343 R. Hod, E. Jacob, O. Avni, Israel UNCONVENTIONAL ASSOCIATION OF THE POLYCOMB GROUP PROTEINS WITH THE CYTOKINE GENES IN DIFFERENTIATED Th CELLS

PB-344 A. Kaplan, S. Kotzer, M. Salmon-Divon, C.R. Almeida, P. Hoglund, D.M. Davis, R. Mehr, Israel MODELING NATURAL KILLER CELL IMMUNOLOGICAL SYNAPSES

101 Poster Session B – Royal Beach (continued)

PB-345 E. Khvalevsky, R. Abramovitch, H. Barash, I. Spivak-Pohis, L. Rivkin, Israel, Y-T. Azuma, USA, J. Rachmilewitz, H. Giladi, E. Galun, Israel TLR3 SIGNALING ATTENUATES LIVER REGENERATION

PB-346 M. Salmon-Divon, Israel, S. Johansson, M. Johansson, P. Hoglund, Israel, R. Mehr, Israel MODELING NATURAL KILLER CELL DEVELOPMENT AND REPERTOIRE FORMATION

PB-347 A. Meiraz, O. Gal Garber, D. Hassin, G. Berke, Israel IS PERFORIN THE HALLMARK OF CTL ACTIVITY

PB-348 M. Oren, J. Douek, Z. Fishelson, B. Rinkevich, Israel IDENTIFICATION OF IMMUNE-RELEVANT GENES IN HISTOINCOMPATIBLE REJECTING COLONIES OF THE TUNICATE BOTRYLLUS SCHLOSSERI

PB-349 O. Rechavi, I. Goldstein, H. Vernitsky, B. Rotblat, Y. Kloog, Israel INTERCELLULAR TRANSFER OF ONCOGENIC H-Ras AT THE IMMUNOLOGICAL SYNAPSE

PB-350 A. Sapoznikov, Y. Pewzner-Jung, V. Kalchenko, R. Krauthgamer, I. Shachar, S. Jung, Israel DENDRITIC CELLS DEFINE CRITICAL PERIVASCULAR BONE MARROW NICHES FOR MATURE B CELL SURVIVAL

PB-351 D. Sherf, A. Porgador, Israel EXPRESSING HUMAN NCRS USING YEAST SURFACE DISPLAY LIBRARY AND CHARACTERIZE THESE RECEPTORS AFTER DIRECTED EVOLUTION

PB-352 N. Stanietsky, H. Achdout, N. Stern-Ginossar, G. Betser-Cohen, O. Mandelboim, Israel VSIG9: A NOVEL INHIBITORY RECEPTOR OF THE B7 FAMILY INTERACTS WITH CD155

PB-353 N. Stern-Ginossar, E. Horwitz, M. Biton, O. Mandelboim, Israel SHARED TARGET SEQUENCES ARE USED BY BOTH VIRAL AND HUMAN microRNAs TO CONTROL IMMUNE RECOGNITION

PB-354 L. Tuval-Kochen, N. Hadad, R. Levy, Israel ENDOTHELIAL CYTOSOLIC PHOSPHOLIPASE A2 ALPHA IS INVOLVED IN ADHERENCE BETWEEN DIFFERENTIATED PLB-985 CELLS AND ENDOTHELIAL CELLS

PB-355 C. Varol, A. Vallon-Eberhard, S. Jung, Israel STUDYING THE IN VIVO ROLE OF MONOCYTES AND DENDRITIC CELLS IN THE DEVELOPMENT OF CHRONIC GUT INFLAMMATION

PB-356 D. Gur-Wahnon, Z. Borovsky, S. Beyth, M. Liebergal, J. Rachmilewitz, Israel IDENTIFICATION OF A NOVEL CONTACT- AND JAK2-DEPENDENT PATHWAY THAT LEADS TO ACTIVATION OF STAT3 SIGNALING IN ANTIGEN PRESENTING CELLS

PB-357 L. Werner, S. Vigodman, Z. Halpern, H. Gur, I. Dotan, Israel THE EFFECTS OF THE CHEMOKINE CXCL12 ON MUCOSAL LYMPHOCYTES IN HOMEOSTASIS AND INFLAMMATION

Ion transport and homeostasis

PB-358 E. Bab-Dinitz, S. Karlish, Israel A THEORETICAL 3D STRUCTURAL MODEL OF THE EXTRACELLULAR DOMAIN OF THE BETA SUBUNIT OF THE Na,K-ATPase

PB-359 T. Belogus, S. Karlish, Israel THE EFFECT OF CHARGE IN THE ACTIVE SITE OF Na,K-ATPase ON E1-E2 CONFORMATIONAL TRANSITIONS

PB-360 S. Berlin, N. Dascal, Israel CATALYTIC COLLISION COUPLING OF THE MUSCARINIC M2 RECEPTOR TO Galpha-i3

PB-361 S. Diminshtein, L. Yu, Israel, D. Becker, R. Hedrich, Germany, X-H. Ma, M. Moshelion, Israel, T. Tzfira, USA, N. Moran, Israel FUNCTIONAL ASSAYS OF SPICK2, THE AKT2 K CHANNEL HOMOLOG FROM MOTOR CELLS OF SAMANEA SAMAN

102 Poster Session B – Royal Beach (continued)

PB-362 A. Dror, H. Shahin, Israel, H. Fuchs, M. Hrabe de Angelis, Germany, K.B. Avraham, Israel A NEW MOUSE MODEL FOR HEARING AND VESTIBULAR DYSFUNCTIONS REVEALED BY A PHENOTYPE-DRIVEN APPROACH

PB-363 A. Enosh, B. Raveh, D. Halperin, N. Ben-Tal, Israel METHODS FOR PATH PLANNING, COMPARISON, AND CLUSTERING SUGGEST PATHWAYS BETWEEN THE OPEN AND CLOSED CONFORMATIONS OF THE KcsA CHANNEL

PB-364 H. Haviv, R. Goldschleger, T. Belogus, E. Bab-Dinitz, Y. Lifshitz, E. Cohen, D.M. Tal, S.J.D. Karlish, Israel THE SODIUM PUMP: STRUCTURAL AND FUNCTIONAL STUDIES OF AN IMPORTANT MEMBRANE PROTEIN

PB-365 L. Kozachkov, L. Galili, K. Herz, E. Padan, Israel FUNCTIONAL AND STRUCTURAL INTERACTIONS OF TMS X IN NHAA NA+/H+ ANTIPORTER OF ESCHERICHIA COLI

PB-366 I. Lubarski, S. Karlish, H. Garty, Israel STRUCTURAL AND FUNCTIONAL INTERACTION BETWEEN FXYD5 AND THE Na(+)/K(+)-ATPase

PB-367 S. Moshitzky, H. Garty, Israel FUNCTIONAL INTERACTION BETWEEN PLM, NA+/K+ ATPASE AND NA+/CA2+ EXCHANGER

PB-368 E. Petrovich, H. Garty, Israel CHARACTERIZATION OF Na(+)/K(+)-ATPase DOMAINS INVOLVED IN STRUCTURAL INTERACTIONS WITH FXYD2 (THE GAMMA SUBUNIT)

PB-369 M. Schushan, Israel, M. Xiang, R. Rao, USA, N. Ben-Tal, Israel A MODEL-STRUCTURE OF HsNha2, POSSIBLY A NOVEL EXCHANGER OF Li+/Na+, SUGGESTS TITRATABLE RESIDUES THAT MAY BE INVOLVED IN ION TRANSPORT

Neurons and synapses

PB-370 O. Avraham, A. Klar, Israel DECIPHERING THE AXONAL GUIDANCE OF SPINAL SENSOTY INTERNEURONS

PB-371 L. Balan, V.N. Foltyn, E. Dumin, H. Wolosker, Israel FEEDBACK INHIBITION OF D-SERINE SYNTHESIS BY NMDA RECEPTOR ACTIVATION

PB-372 N. Bielopolski, O. Yizhar, U. Ashery, Israel TOMOSYN'S INTRAMOLECULAR AND INTERMOLECULAR DYNAMICS

PB-373 Y. Blumenthal, I. Ginzburg, Israel ZINC AS A TRANSLATION REGULATOR IN NEURONS: EFFECT ON RNP INTERACTIONS AND P-BODIES AGGREGATION

PB-374 H. Cohen Ben-Ami, H. Farah, M. Treinin, Israel SUBUNIT SPECIFIC INTERACTIONS OF RIC-3 ENABLE ITS EFFECTS ON NICOTINIC ACETYLCHOLINE RECEPTOR PROPERTIES

PB-375 T. Licht, I. Goshen, A. Avital, M. Segal, R. Yirmiya, E. Keshet, Israel VEGF IMPROVES HIPPOCAMPUS-DEPENDENT MEMORY BY ENHANCING SYNAPTIC PLASTICITY

PB-376 E. Magidovich, O. Yifrach, Israel THE C-TERMINAL DOMAIN OF THE SHAKER VOLTAGE-ACTIVATED POTASSIUM CHANNEL IS INTRINSICALLY-DISORDERED

PB-377 A. Paz, T. Zeev-Ben-Mordehai, I. Silman, J.L. Sussman, Israel STRUCTURAL AND FUNCTIONAL STUDIES ON THE CHOLINESTERASE-LIKE ADHESION MOLECULES AND THEIR BINDING PARTNERS

103 Poster Session B – Royal Beach (continued)

PB-378 C. Sagy-Bross, N. Hadad, R. Levy, Israel THE ROLE OF CYTOSOLIC PHOSPHOLIPASE A2 ALPHA IN NEURONAL DEGENERATION

PB-379 A. Hashahar Shapira, G. Jackobson, I. Nelken, Israel THE ECTOSYLVIAN SULCAL AUDITORY FIELD (FAES) AND LOCALIZATION OF SOUNDS

PB-380 R. Shema, Y. Dudai, Israel RAPID ERASURE OF REMOTE MEMORY ASSOCIATIONS IN CORTEX BY AN INHIBITOR OF PKMzeta

PB-381 T. Vaisid, N.S. Kosower, E. Elkind, S. Barnoy, Israel AMYLOID-BETA PEPTIDE TOXICITY IN DIFFERENTIATED PC12 CELLS: CALPAIN-CALPASTATIN, CASPASE AND MEMBRANE DAMAGE

PB-382 Withdrawn

Psychology-biology interface

PB-383 M. Cohen, Z. Malik, Israel STIMULATION OF SKIN CELLS BY INTENSE PULSED LIGHT, RADIOFREQUENCY ENERGY AND ALA: A MODEL OF SKIN PHOTOREJUVENATION

PB-384 R. Keren-Hacmon, N. Kronfeld-Schor, Israel THE MECHANISMS UNDERLYING BEHAVIORAL PHENOTYPES IN THE RESPONSE TO FOOD RESTRICTION IN GOLDEN SPINY MICE

Stem cells and organ formation

PB-385 R. Antes, L. Shistik, C. Yoffe, R. Ashery-Padan, Israel ROLES OF Pax6 IN RETINAL PIGMENTED EPITHELIUM (RPE) DEVELOPMENT

PB-386 H. Bahar, G. Shefer, A. Yaffe, D. Benayahu, I. Binderman, Israel EXPRESSION OF PARATHYROID HORMONE RECEPTOR 1 (PTH1-RC) IN BONE MARROW DERIVED MESENCHYMAL STEM CELLS (MSC)

PB-387 Y. Cabilly, O. Elroy-Stein, Israel A POINT MUTATION IN eIF2B5 IMPAIRS THE POTENTIAL OF BONE MARROW-DERIVED STEM CELLS TO DIFFERENTIATE INTO ASTROCYTE-LIKE CELLS

PB-388 M.A. Cohen, P. Itsykson, B.E. Reubinoff, Israel THE MOLECULAR MECHANISM OF NEURAL INDUCTION OF HUMAN EMBRYONIC STEM CELLS

PB-389 N. Davis-Silberman, Israel, J. Berger, E. Tamm, Germany, R. Ashery-Padan, Israel GENETIC DISSECTION OF Pax6 DOSAGE REQUIRMENTS IN THE DEVELOPING IRIS

PB-390 C. Farhy, V. Oron-Karni, P. Oren-Giladi, M. Elgart, R. Ashery-Padan, Israel Pax6 LOSS DISCLOSES INTRINSIC VARIANCE AMONG RPCs

PB-391 M. Gropp, B.E. Reubinoff, Israel LENTIVIRAL-RNA-INTERFERENCE SYSTEM MEDIATING HOMOGENOUS AND MONITORED LEVEL OF GENE SILENCING IN HUMAN EMBRYONIC STEM CELLS

PB-392 I. Harel, E. Tzahor, Israel THE EMBRYONIC ORIGIN OF SATELLITE CELLS IN THE HEAD MUSCULATURE

PB-393 L. Hinden, G. Etinger, Y. Azar, R. Or, Israel BONE MARROW AND BONE MARROW DERIVED MESENCHYMAL CELLS TRANSPLANTATION AS A TREATMENT FOR DIABETES IN MICE

104 Poster Session B – Royal Beach (continued)

PB-394 G.I. Keshet, I. Goldstein, O. Yitzhaki, K. Cesarkas, A. Yakirevitch, A.J. Treves, J. Schachter, N. Amariglio, G. Rechavi, Israel MDR1 EXPRESSION IDENTIFIES A UNIQUE POPULATION OF SELF-RENEWING CELLS IN HUMAN MELANOMA

PB-395 S. Lefler, M. Weil, Israel IN VIVO APPROACH FOR NEURAL DIFFERENTIATION OF HUMAN STEM CELLS IN THE DEVELOPING CHICK EMBRYO: A PLATFORM TO STUDY HUMAN NEURODEGENERATIVE DISEASES

PB-396 E. Nathan, A. Monovich, L. Tirosh-Finkel, Israel, Z. Harrelson, USA, T. Rousso, A. Rinon, Israel, S. Evans, USA, E. Tzahor, Israel THE CONTRIBUTION OF Islet1-EXPRESSING SPLANCHNIC MESODERM CELLS TO DISTINCT JAW MUSCLES REVEALS SIGNIFICANT HETEROGENEITY IN HEAD MUSCLE DEVELOPMENT

PB-397 H. Tuby, L. Maltz, U. Oron, Israel IMPLANTATION OF LOW-LEVEL LASER IRRADIATED MESENCHYMAL STEM CELLS INTO THE INFARCTED RAT HEART IS ASSOCIATED WITH REDUCTION IN INFARCT SIZE

PB-398 T. Re'em, O. Tsur-Gang, S. Cohen, Israel CHONDROGENIC DIFFERENTIATION OF HUMAN MESENCHYMAL STEM CELLS CULTIVATED WITHIN RGD-ALGINATE SCAFFOLDS

PB-399 O. Shaham, Israel, M.L. Robinson, USA, R. Ashery-Padan, Israel Pax6 IS ESSENTIAL FOR LENS FIBER CELL DIFFERENTIATION

PB-400 R. Shainer, E. Gaberman, D. Belenky, L. Levdansky, R. Gorodetsky, Israel FIBRIN MICROBEADS (FMB) WITH MICRONIZED COLLAGEN FOR EFFICIENT ISOLATION, CHONDROGENIC DIFFERENTIATION AND IMPLANTATION OF ADULT MESENCHYMAL STEM CELLS (MSC)

PB-401 G. Shefer, G. Rauner, Israel, Z. Yablonka-Reuveni, USA, D. Benayahu, Israel USE IS OR LOOSE IT – EXERCISE RUNNING AS A MEANS TO MAINTAIN QUANTITY AND QUALITY OF SKELETAL MUSCLE STEM CELLS

PB-402 O. Veinblat, U-D. Akavia, D. Benayahu, Israel COMPARISON ANALYSIS OF TRANSCRIPTIONAL PROFILING BETWEEN MESENCHYMAL CELLS WITH CARDIAC AND SKELETAL MUSCLE CELLS

PB-403 M. Zusev, D. Benayahu, Israel MS-KIF18A KINESIN IS REGULATED BY ESTRODIOL AND BINDS ESTROGEN RECEPTOR IN MARROW STROMAL CELLS

Stress responses

PB-404 M. Abramson, S. Lapidot, M. Dekel, Z. Shani, U. Kafkafi, O. Shoseyov, Israel SALINITY TOLERANCE CONFERRED BY EXPRESSION OF PEA PECTIN METHYLESTERASE (PME) IN TRANSGENIC TOBACCO

PB-405 Y. Aylon, D. Michael, A. Shmueli, Israel, N. Yabuta, H. Nojima, Japan, M. Oren, Israel A POSITIVE FEED BACK LOOP BETWEEN THE p53 AND Lats2 TUMOR SUPPRESSORS PREVENTS TETRAPLOIDIZATION

PB-406 Y. Bar-Yosef, A. Sukenik, A. Kaplan, Israel "MODERN ENSLAVEMENT" IN PHYTOPLANKTON COMMUNITIES?

PB-407 D. Bar-Zvi, Z. Konrad, S. Rom, D. Shkolnik, N. Shadrin, Israel, R. Ghirlando, USA, Y. Goldgur, Israel STRUCTURE-FUNCTION STUDIES OF TOMATO ASR1, A WATER STRESS- AND SALT STRESS- REGULATED PLANT-SPECIFIC PROTEIN

PB-408 E. Berenshtein, M. Chevion, Israel A NEW IRON-BASED MECHANISM OF HEART PROTECTION BY PRECONDITIONING

PB-409 B. Bulvik, L. Grinberg, R. Eliashar, E. Berenshtein, M. Chevion, Israel

105 IRON, FERRITIN AND PROTEINS OF THE METHIONINE - CENTERED REDOX CYCLE IN YOUNG AND OLD RAT HEARTS Poster Session B – Royal Beach (continued)

PB-410 Withdrawn

PB-411 Y. Golan, S. Ufaz, G. Galili, Israel, C. Koncz, Germany, A. Zilberstein, Israel A NEW MODE OF TRANSCRIPTION REGULATION CONTROLLING THE ASPARTATE-DERIVED AMINO ACID BIOSYNTHESIS PATHWAYS UNDER ENERGY DEPLETION IN PLANTS

PB-412 Y. Golani, A. Levine, Israel A NOVEL ZINC FINGER HAS AN IMPORTANT ROLE IN PLANT RESPONSE TO SALT STRESS

PB-413 A. Honig, O. Erster, H. Stein, M. Abu-Abied, E. Belausov, E. Sadot, A. Zilberstein, Israel TOWARDS UNDERSTANDING THE CELLULAR FUNCTION OF ARABIDOPSIS THALIANA CELL WALL LINKER PROTEIN (CWLP) AND ITS INVOLVEMENT IN DROUGHT TOLERANCE

PB-414 Y. Kaye, A. Levine, Israel PLANT RESPONSE TO SALT STRESS IS REGULATED BY VESICLE TRAFFICKING

PB-415 Z. Cohen, T. Blustein, S. Lavi, Israel INSTABILITY OF SATELLITE DNA AND THE FORMATION OFEXTRACHROMOSOMAL CLOSED CIRCULAR DNA (eccDNA)

PB-416 A. Lavut, K. Baranes, O. Krichevsky, D. Raveh, Israel CROSS-TALK BETWEEN DIFFERENT STRESS TRANSDUCER MODULES: UFO1 REGULATION REVEALS INTERACTIONS BETWEEN THE OXIDATIVE STRESS, PLEIOTROPIC DRUG AND DNA DAMAGE RESPONSE PATHWAYS

PB-417 G. Mass, Israel, W.H. Cheng, USA, E. Berkovich, Israel, V.A. Bohr, USA, Y. Shiloh, Israel FUNCTIONAL LINK BETWEEN ATAXIA-TELANGIECTASIA AND WERNER SYNDROME

PB-418 O. Murik, A. Kaplan, Israel ACQUIRING ANTI OXIDATIVE ACTIVITY SENSITIZES PHYTOPLANKTON CELLS TO OXIDATIVE STRESS AND PROGRAMMED CELL DEATH

PB-419 N. Nir, M. Bahalul, T. Katz-Ezov, Y. Kashi, A. Fishman, Israel IMPROVEMENT OF NATURAL ISOLATES OF SACCHAROMYCES CEREVISIAE STRAINS FOR SYNTHESIS OF A CHIRAL BUILDING BLOCK USING CLASSIC GENETICS

PB-420 Y. Ofir-Rosenfeld, Israel, K. Boggs, USA, D. Michael, Israel, M. Kastan, USA, M. Oren, Israel RIBOSOMAL PROTEIN L26 IS BOTH A MODULATOR AND A SUBSTRATE OF Mdm2 E3 ACTIVITY

PB-421 A. Pri-Or, O. Ernst, A. Parnas, A. Azem, T. Zor, Israel DETERMINATION OF THE REQUIREMENT OF Hsp60/10 COMPLEX FORMATION FOR THE ANTI-INFLAMMATORY ACTIVITY OF Hsp10

PB-422 S. Rashi-Elkeles, R. Elkon, S. Shavit, Y. Lerenthal, C. Linhart, N. Amariglio, G. Rechavi, R. Shamir, Y. Shiloh, Israel A FUNCTIONAL GENOMICS APPROACH TO THE DISSECTION OF THE p53-MEDIATED TRANSCRIPTIONAL RESPONSE TO DNA DAMAGE

PB-423 N. Reznik, G. Miller, H. Stein, H. Hefetz, A. Zilbestein, Israel A NOVEL FORWARD GENETICS APPROACH TO IDENTIFY GENES INVOLVED IN ABIOTIC STRESS SIGNALING PATHWAYS IN PLANTS

PB-424 R. Nagler, D. Savulescu, S. Leschiner, M. Gavish, Israel CHARACTERIZATION AND MONITORING OF SALIVARY TRANSLOCATOR PROTEIN (TSPO) UNDER PHYSIOLOGICAL CONDITIONS AND FOLLOWING EXPOSURE TO CIGARETTE SMOKE

PB-425 A. Shahar, Y. Kashi, N. Adir, Israel STRUCTURE AND FUNCTION OF Cpn60.2 FROM MYCOBACTERIUM TUBERCULOSIS

106 Poster Session B – Royal Beach (continued)

PB-426 A. Shatil, M. Moshelion, Israel BUNDLE SHEATH TRACHEID COMPLEXES ARE LIKELY TO REGULATE WATER TRANSFER FROM XYLEM TO THE ATMOSPHERE

PB-427 A. Tidhar, Y. Flashner, D. Gur, Y. Levy, M. Aftalion, S. Lazar, E. Elhanany, A. Zauberman, A. Shafferman, S. Cohen, E. Mamroud, Israel THE NlpD LIPOPROTEIN IS A NOVEL Y. PESTIS VIRULENCE FACTOR ENCODED FROM A PUTATIVE STRESS RESPONSE LOCUS

PB-428 Z. Tietel, Y. Vinokur, B. Horev, V. Rodov, Israel IMPROVEMENT OF NUTRITIONAL QUALITY AND MICROBIAL SAFETY OF FRESH-CUT ONIONS BY PHOTOBIOLOGICAL TREATMENT

PB-429 V. Vinokur, B. Bulvik, E. Berenshtein, L. Grinberg, R. Eliashar, M. Chevion, Israel IRON HOMEOSTASIS AND REDOX PROTECTION IN RESPONSE TO ISCHEMIC PRECONDITIONING OF THE HEART IN DIABETIC RATS

PB-430 A. Weiner, E. Shimoni, I. Sabanay, A. Minsky, Israel DOUBLE STRANDED DNA BREAKS RESULT IN CHROMATIN CONDENSATION IN BACILLUS SUBTILIS

PB-431 I. Yehuda, J. Avital, S. Tamir, Israel THE POTENTIAL USE OF PHYTOESTROGENS IN CIRCUMVENTING THE LOSS OF ESTROGEN PROTECTIVE FUNCTIONS

PB-432 S. Yehudai-Resheff, Israel, D.B. Stern, USA THE CHLOROPLAST AS A STORAGE SITE FOR PHOSPHATE IN PLANTS

PB-433 S. Zeno, L. Veenman, S. Leschiner, M. Zaarur, G. Moshe, Israel THE TRANSLOCATOR PROTEIN (TSPO) AND APOPTOSIS UNDER HYPOXIC CONDITIONS

The molecular basis of diseases

PB-434 A.H. Abbasi, H.J. Garzozi, T. Ben-Yosef, Israel A NOVEL SPLICE-SITE MUTATION OF TULP1 UNDERLIES SEVERE EARLY-ONSET RETINITIS PIGMENTOSA IN A CONSANGUINEOUS ISRAELI MUSLIM ARAB FAMILY

PB-435 M. Basheer, H. Schwalb, D. Gilon, V. Dopinner, Y. Sherman, R. Gorodetsky, Israel EFFECT OF FIBRINOGEN C-TERMINAL SEQUENCES (HAPTIDES) OR FIBRIN DEGRADATION PRODUCTS ON CARDIAC FUNCTION

PB-436 L. Benayoun, E. Granot, L. Rizel, S. Allon-Shalev, D. M. Behar, T. Ben-Yosef, Israel ABETALIPOPROTEINEMIA IN ISRAEL: A FOUNDER MUTATION IN THE ASHKENAZI JEWISH POPULATION AND A CONTIGUOUS GENE DELETION IN AN ARAB PATIENT

PB-437 T. Yardeni, Y. Anikster, R. Shapiro, Y. Bujanover, D. Bercovich, Israel GENOTYPE ANALYSIS OF PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS

PB-438 K. Bloch, E. Shichman, M. Vorobeychik, D. Bloch, P. Vardi, Israel CATALASE LOCALIZATION IN PANCREATIC ALPHA CELLS OF DIABETIC AND NON DIABETIC MICE

PB-439 O. Bloch, Y. Molad, E. Yona, M. Amit, M.J. Rapoport, Israel INCREASED EXPRESSION OF pERK AND pJNK KINASES IN PERIPHERAL BLOOD MONONUCLEAR CELLS REFLECTS DISEASE ACTIVITY IN SYSTEMIC LUPUS ERYTHEMATOSIS PATIENTS

PB-440 Z.N. Brownstein, O. Dagan, D. Giloni, Israel, T. Walsh, M-C. King, USA, M. Kanaan, Palestinian Authority, M. Shohat, M. Frydman, K.B. Avraham, Israel NUMBER OF DEAFNESS GENES IN ISRAEL: UP TO 10

PB-441 I. Dar, G. Yoshai, R. Galron, Israel, Z-Q. Wang, Israel/Germany, Y. Shiloh, Germany, A. Barzilai, Israel ATM PROTEIN IS NOT FULLY EPISTATIC WITH Nbs1 IN THE CENTRAL NERVOUS SYSTEM

107 Poster Session B – Royal Beach (continued)

PB-442 A. Elimelech, Y. Anikster, G. Schwartz, S. Korem, T. Yardeni, J. Zlotogora, N. Gal, N. Goldstein, B. Vilensky, S. Avraham, R. Loewenthal, D. Bercovich, Israel MULTI-ORIGIN POPULATION GENOTYPE-PHENOTYPE ANALYSIS OF THE PAH GENE IN PKU PATIENTS

PB-443 A. Rimon, T. Tzuberi, E. Padan, Israel MONOMERS OF NhaA Na+/H+ ANTIPORTER OF ESCHERICHIA COLI ARE FULLY FUNCTIONAL YET DIMERS ARE BENEFICIAL UNDER EXTREME STRESS CONDITIONS AT ALKALINE pH IN THE PRESENCE OF Na+ OR Li+

PB-444 D. Filon, Israel, M. Phylipsen, P. Giordano, The Netherlands, A. Oppenheim, D. Rund, Israel, C.L. Harteveld, The Netherlands FOUR NOVEL DELETIONS IN GLOBIN GENES REVEALED BY MULTIPLEX LIGATION DEPENDENT PROBE AMPLIFICATION (MLPA) TECHNOLOGY

PB-445 A. Solomon, K. Baranes, A. Nitzan, R. Galron, U. Fishelson, Y. Rotenstreich, Y. Assaf, Y. Shiloh, A. Barzilai, Israel CRITICAL ROLE OF THE Nbs1 PROTEIN IN THE DEVELOPMENT AND FUNCTION OF THE MOUSE VISUAL SYSTEM

PB-446 N. Gil-Maslennikov, E. Zcharia, I. Vlodavsky, M. Elkin, Israel INVOLVEMENT AND REGULATION OF HEPARANASE ENZYME IN DIABETIC NEPHROPATHY

PB-447 D. Gurevitch, S. Boura-Halfon, D. Ronen, Y. Zick, Israel PHOSPHORYLATION OF SELECTED SERINES IN THE PTB DOMAIN OF IRS-2 HIGHLY REGULATES BETA CELL GROWTH, SURVIVAL, AND INSULIN SECRETION

PB-448 L. Hammer, I. Solomonik, R. Yehuda, A. Carmely, Israel, J. Huelsken, W. Birchmeier, Germany, B. Bartoov, T. Tennenbaum, Israel THE ABSENCE OF BETA-CATENIN, KERATIN 14 PROMOTER DRIVEN, IS ASSOCIATED WITH IMPAIRED FERTILITY IN MALES

PB-449 T. Harel, A. Katz, R. Ofir, V. Caspi, O.S. Birk, Israel GENE EXPRESSION PROFILING IN THE DEVELOPING NEURAL TUBE

PB-450 T. Hasin, I. Kehat, A. Aronheim, Israel A NOVEL ANGIOTENSIN RECEPTOR SIGNALING PATHWAY MEDIATING ATRIAL DILATATION

PB-451 Withdrawn

PB-452 Y. Keselman, N. Gollop, I. Litmani, I. Peri, B. Schwartz, Israel THE ROLE OF GUT BARRIER PROTEINS IN NECROTIZING ENTEROCOLITIS

PB-453 L. Landsman, L. Bar-On, Israel, A. Zernecke, Germany, K-W. Kim, R. Krauthgamer, Israel, S.A. Lira, I.L. Weissman, USA, C. Weber, Germany, S. Jung, Israel CX3C CHEMOKINE-MEDIATED SURVIVAL SIGNALS IN MONOCYTE HOMEMOSTASIS AND ATHEROGENESIS

PB-454 M. Kirshner, M. Finkel, A. Nitzan, Israel, R. Kanaar, The Netherlands, Y. Shiloh, A. Barzilai, Israel ANALYSIS OF THE INTER-RELATIONS BETWEEN ATM-MEDIATED PATHWAYS AND HOMOLOGOUS RECOMBINATION DNA REPAIR

PB-455 O. Klebanov, A. Nitzan, A. Barzilai, A.S. Solomon, Israel SEMAPHORIN-3A EXPRESSION AND ASSOCIATED BIOCHEMICAL AND CELLULAR EVENTS IN EXPERIMENTAL RETINAL DETACHMENT MODEL IN RAT

PB-456 C. Shochat, E. Elimelech, T. Yardeni, S. Korem, D. Bercovich, Israel MUTATION DETECTION IN THE TP-53 GENE BY THE HI-RESOLUTION MELTING TECHNIQUE

PB-457 S. Krichevsky, E. Prus, J. Abramowitz, A. Treves, R. Perlman, E. Fibach, D. Ben-Yehuda, Israel THE JAK2V617F MUTATIONS IN NORMAL AND MYELOPROLIFERATIVE HEMATOPOIESIS

PB-458 D. Krutauz, M.H. Glickman, Israel Rpn10 AS A TARGET OF UBB+1, AN INHIBITOR OF UBIQUITIN-PROTEASOME DEGRADATION

108 Poster Session B – Royal Beach (continued)

PB-459 D.R. Lenz, Israel, H. Fuchs, M.H. de Angelis, Germany, K.B. Avraham, Israel THE SEARCH FOR MODIFIERS USING THE MENEO ENU MOUSE MUTANT, A MODEL FOR HUMAN VESTIBULAR DYSFUNCTION

PB-460 T. Tchaikovskaya, USA, V. Fraifeld, Israel, T. Urphanishvili, E. Milova, E. Rubashevsky, M. Cammer, R. Sellers, I. Listowsky, USA REPRODUCTIVE FUNCTIONS OF GLUTATHIONE TRANSFERASE M5 NULL MICE

PB-461 H. Meir, M. Rosenbaum, Y. Azar, R. Or, Israel GENE EXPRESSION PATTERNS IN MURINE T-CELLS AFTER SEMI-ALLOGENEIC BONE MARROW TRANSPLANTATION

PB-462 I. Michael, M. Shmoish, Israel, D.S. Walton, USA, S. Levenberg, Israel INTERACTIONS BETWEEN TRABECULAR MESHWORK CELLS AND LENS EPITHELIAL CELLS – A POSSIBLE MECHANISM IN INFANTILE APHAKIC GLAUCOMA

PB-463 M. Nissim-Rafinia, Y. Benharosh, B. Kerem, Israel RESTORATION OF THE CFTR FUNCTION BY SPLICING MODULATION

PB-464 A. Nitzan, A. Barzilai, A.S. Solomon, Israel RESTORATION OF OPTIC NERVE ORGANIZATION AND REMOVAL OF REPULSIVE CUES ENHANCE AXONAL REGENERATION

PB-465 S. Rosenzweig, A. Nitzan, M. Paz, Israel, G. Jeserich, Germany, G. Neufeld, A. Barzilai, A.S. Solomon, Israel INTRAOCULAR Sema-3A INJECTION DISRUPTS REGENERATION OF AXOTOMIZED GOLDFISH OPTIC NERVE

PB-466 S. Porat, Z. Granot, Israel, M.A. Magnuson, USA, Y. Dor, Israel GLUCOSE FLUX IS A MAJOR DETERMINANT OF PANCREATIC BETA CELL PROLIFERATION

PB-467 Y. Rachminov, E. Barhurdar, U. Nir, A. Karasik, R. Hemi, H. Kanety, Israel A NOVEL FUNCTIONAL LINK BETWEEN STRESS KINASES CASCADES AND ErbB RECEPTORS PATHWAYS IN LIVER INSULIN RESISTANCE

PB-468 A. Rebibo Sabbah, I. Nudelman, Israel, Z.M. Ahmed, T.B. Friedman, USA, T. Baasov, T. Ben-Yosef, Israel EVALUATING SUPPRESSION OF NONSENSE MUTATIONS BY AMINOGLYCOSIDE ANTIBIOTICS AS AN INTERVENTION FOR VISION LOSS IN TYPE I USHER SYNDROME

PB-469 S. Salpeter, Z. Granot, S. Porat, Y. Dor, Israel GLUCOSE REGULATES CONSTITUTIVE CYCLIN D2 EXPRESSION IN PANCREATIC BETA CELLS

PB-470 Y. Salzberg, S. Bar-Sheshet Itach, O. Karminsky, J. Don, Israel Meig1 DEFICIENCY CAUSES A SEVERE DEFECT IN MOUSE SPERMATOGENESIS

PB-471 O. Sapognikov, Y. Gocheva, M. Gutnick, N. Movshovich, K. Baranes, A. Bakhrat, D. Bar-Zvi, R. Parvari, L. Gheber, D. Raveh, Israel TUBULIN CHAPERONE E/YEAST Pac2 BINDS PROTEASOMES AND MICROTUBULES AND AFFECTS PROTEASOME FUNCTION UNDER STRESS

PB-472 T. Yardeni, C. Shochat, S. Korem, D. Bercovich, Israel BRCA-1 ROBUST MUTATION SCREENING BY HIGH-RESOLUTION MELTING ANALYSIS

PB-473 S.B. Wallach-Dayan, R. Golan-Gerstl, Israel, R. Breue, Israel/USA EVASION OF MYOFIBROBLASTS FROM IMMUNE SURVEILLANCE: A MECHANISM FOR TISSUE FIBROSIS

PB-474 H. Shoval, L. Weiner, E. Gazit, M. Levy, I. Pinchuck, D. Lichtenberg, Israel POLYPHENOLS-INDUCED DISSOCIATION OF AMYLOID FIBRILS IS ACCOMPANIED BY THE FORMATION OF FREE RADICALS

109 Poster Session B – Royal Beach (continued)

PB-475 T. Tenne, T. Sobe, K.B. Avraham, Israel INTERACTIONS BETWEEN MYOSIN VI AND INTERACTING PROTEINS IN THE SENSORY HAIR CELL

PB-476 M. Vecsler, A.J. Simon, G. Rechavi, N. Amariglio, E. Gak, Israel MECHANISMS OF MeCP2 FUNCTION UNDERLYING RETT SYNDROME AS REVEALED FROM TRANSGENIC AND KNOCK-DOWN SYSTEMS IN VITRO

PB-477 S. Vekslin, N. Auslender, D. Sharon, A.H. Abbasi, H.J. Garzozi, E. Banin, T. Ben-Yosef, Israel GENETIC AND MOLECULAR CHARACTERIZATION OF CERKL: A GENE UNDERLYING AUTOSOMAL RECESSIVE SEVERE RETINAL DEGENERATION WITH EARLY MACULAR INVOLVEMENT IN THE YEMENITE JEWISH POPULATION

PB-478 G. Wekselman, D.R. Lenz, O. Hermesh, Israel, H. Fuchs, Germany, K.P. Steel, UK, M.H. Angelis, Germany, K.B. Avraham, Israel ENU MOUSE MUTANTS: MODELS FOR HUMAN HEARING IMPAIRMENT

PB-479 S. Yehezkel, Y. Segev, K. Skorecki, S. Selig, Israel DNA METHYLATION OF HUMAN SUBTELOMERIC REGIONS- LESSONS FROM ICF SYNDROME

PB-480 A. Yaniv, R. Galron, I. Shapira, A. Nitzan, T. Blumenfeld-Katzir, N. Ziv, A.S. Solomon, V. Holdengreber, Israel, Z-Q. Wang, Germany, Y. Shiloh, A. Barzilai, Israel MRI EVIDENCE OF WHITE MATTER DAMAGE IN A MOUSE MODEL OF NIJMEGEN BREAKAGE SYNDROME

110