Sight and Life 3 2006
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SIGHT AND LIFE Magazine Issue No 1/2007 Carotenoid function Food vouchers Nutritional status in Guatemala DOHaD SLAN Education ANLP A Life in the Day Recent literature Publications News Food distribution by the United Nations World Food Programme Building bridges to combat malnutrition “The life science industry is able to make a major contribution to fighting global mal- nutrition and hunger,” stated Feike Sijbesma (President of SIGHT AND LIFE and incoming CEO of DSM) at a special session of the BioVision conference in Lyon. He announced a global humanitarian partnership with the United Nations World Food Programme (WFP), the largest provider of food aid to the world's hungry. SIGHT AND LIFE presented the book Nutritional Anemia at BioVision 2007. More on the book and the partnership can be found on page 60. SIGHT AND LIFE Contents Impact of vouchers for purchasing fresh fruits and vegetables among low-income The African Forum mothers 13 Lusaka, Zambia, May 2006 30 Correspondents Bruno de Benoist Philip Harvey Florentino S Solon William S Blaner Richard F Hurrell Alfred Sommer Martin Bloem Rolf D W Klemm David I Thurnham George Britton Donald S McLaren Andrew Tomkins Ian Darnton-Hill Regina Moench-Pfanner Emorn Wasantwisut Omar Dary Christine Northrop-Clewes Keith P West Jr Frances R Davidson Delia Rodriguez-Amaya Yu Xiaodong John W Erdman Jr Noel W Solomons Michael B Zimmermann 2 Contents Magazine Issue 1/2007 The fifth African Nutrition Leadership SIGHT AND LIFE presented the book Programme (ANLP) 36 Nutritional Anemia at BioVision 2007 60 Contents Welcome 4 From farming to human nutrition 34 Antioxidant nutrients and oxidative The fifth African Nutrition Leadership DNA damage in humans 6 Programme (ANLP) 36 Impact of vouchers for purchasing A Life in the Day of Parul Christian 39 fresh fruits and vegetables among low-income mothers 13 Erratum 41 The nutritional status of Guatemalan From vitamin A to multiple micronutrients 42 schoolchildren 18 Recent literature The 4th World Congress on Letters to the editors 52 Developmental Origins of Health and Disease (DOHaD) 21 Publications 56 The 14th Latin American Congress News 60 on Nutrition (SLAN) 27 Building bridges to combat malnutrition Outstanding Health Research Award The African Forum: An integrated Healthy Eyes Activity Book response to the dual epidemics of HIV/AIDS and food insecurity 30 3 SIGHT AND LIFE Welcome Welcome Malnutrition scandal At the end of last year I was distressed by an article on this account, we have initiat- malnutrition in Ethiopia that was published in the New ed a series of activities. York Times on December 28, 2006. It was titled SIGHT AND LIFE hosted a “Malnutrition Is Cheating Its Survivors and Africa’s workshop on nutritional Future.” The article’s author Michael Wines wrote, anemia last September with “In this corrugated land of mahogany mountains and the leading experts from academia and international tan, parched valleys, it is hard to tell which is the organizations (we reported on this in Issue 3/2006 of greater scandal: the thousands of children malnutrition SIGHT AND LIFE Magazine). We also recently kills, or the thousands more it allows to survive.” published a book, Nutritional Anemia, which provides Indeed, more than 200 million children under the age an account of the information communicatetd at the of 5, mostly living in sub-Saharan Africa and South workshop, and highlights for the first time all the crit- Asia, fail to reach their full cognitive, motor and ical factors of nutritional anemia in one volume. I had socioemotional potential because of micronutrient the pleasure of presenting the first copies of this book deficiencies and inadequate cognitive stimulation. to high-ranking representatives from UNICEF, the These children will probably fail at school, fail to World Food Programme, and the Dutch embassy in achieve their income potential, and remain trapped in France during a special session at BioVision, the poverty. A recent series of papers published in The World Life Sciences Forum, in Lyon on March 11, Lancet also addressed this topic, analyzing the link 2007. More on this topic can be found on page 60. But between compromised development of children and we have even more in mind: the Nutritional Anemia modifiable biological and psychosocial risk factors Guidebook, containing short summaries of the book (Lancet 2007;369:60–70, 145–57 and 229–42). The chapters, will be published shortly, and we are plan- authors call for immediate intervention in four key ning a satellite meeting with the experts who con- areas: stunting, inadequate cognitive stimulation, tributed to the book to correspond with the iodine deficiency, and iron deficiency anemia, the evi- Micronutrient Forum in Istanbul. We need to define dence of which is overwhelming. the next steps in the global fight against anemia, including the specific role that SIGHT AND LIFE will For us at SIGHT AND LIFE, it is not a question of play. defining the greater scandal, but rather of responding to the problem behind it. We intend to champion the There are many factors that contribute to the appraisal fight against micronutrient deficiency, in particular of an organization such as SIGHT AND LIFE, for nutritional anemia, and to ensure that it receives the example the quality of correspondents and partners or recognition merited by the magnitude of the problem. the excellence of projects and publications. One indi- The main causes of anemia are a lack of iron, folic cator rarely recognized, but nevertheless crucial for acid, vitamin B12 and vitamin A, but infectious dis- success, is the willingness to change. We have eases such as malaria, worm infestations, and changed our logo and modernized the layout of our HIV/AIDS also play their part. A total of 818 million magazine to make it more attractive to our readers. women and children under the age of 5 are affected by Additionally, the current edition of the magazine con- anemia, according to recent WHO data. Most of them tains a new column, A Life in the Day of…. In the first live in the developing world and about one million die of this new series, Parul Christian from the Johns every year. Despite the severity of this problem, there Hopkins Bloomberg School of Public Health has been little documented progress in the global fight describes her working day and what lies behind it against anemia over the last decades. Hence there is an (page 39). There are more changes to come, as out- urgent need to control this public health problem. On lined in SIGHT AND LIFE’s strategic framework 4 Welcome Magazine Issue 1/2007 ‘Expanding our Strengths,’ which you can read about Nutrition at the University of Ulster in Northern in the enclosed 2006 Annual Report. The recently Ireland. His first contribution, in which he genteelly announced global humanitarian partnership between introduces both the topic and himself, can be found on the United Nations World Food Programme, DSM, page 42. and SIGHT AND LIFE can also be regarded as a sig- nificant change (see page 60). Permit me to revert briefly to the malnutrition scandal which I mentioned at the outset. We need more advo- In the midst of these planned changes, however, we cacy communication on the fact that the damage to have to report one which comes as a surprise: Donald intellectual capacity cannot be reversed in later life, McLaren has announced that he is stepping down from quantifying the loss of gross domestic product when his position as editor of our literature digest. We wish micronutrient deficiencies are left untreated, which is to thank Don for his critical reviews and thoughtful estimated to cost 2–3% of annual growth in the devel- insight based on the ceaseless commitment to scien- oping world. The problem is not a lack of knowledge tific evidence that he has brought to the vitamin A about solutions but rather the absence of a clear polit- community. Fortunately, we will not have to fully do ical and financial commitment that matches the size of without Don’s wisdom because he is busy working on the malnutrition problem. The problem is clearly the 3rd edition of the SIGHT AND LIFE Manual on described. What remains is to take up the challenge Vitamin A Deficiency Disorders, to be published later and to take action. this year. Best regards, I am particularly pleased that we have been able to enlist David Thurnham to prepare a literature digest – extended not in size but in scope – on multiple micronutrients in the future. David is a widely re- spected figure in micronutrient research. Lately, he has been particularly interested in the influence of inflammation on micronutrients, especially vitamin A and iron. David is Emeritus Professor of Human 5 SIGHT AND LIFE Carotenoid function Antioxidant nutrients and oxidative DNA damage in humans* Kyung-Jin Yeum, Tufts University, Boston; Giancarlo Aldini, Instituto Chimico Farmaceutico e Tossicologico, University of Milan; Robert M. Russell, Tufts University, Boston Correspondence: Kyung-Jin Yeum, Jean Mayer, USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington St., Boston, MA 02111, USA Email: [email protected] * This research has been supported in part by the US Department of Agriculture, under agreement number 1950-51000-048-01A. The contents of this publication do not necessarily reflect the views or policies of the US Department of Agriculture, nor does mention of trade names, commercial products, or organizations imply endorse- ment by the US Government. Introduction etables against reactive oxygen is finely balanced and requires the species has led to the increased right amounts, possibly an optimal Oxidative stress has been impli- consumption of antioxidant supple- range, of both the hydrophilic and cated in the pathogenesis of chron- ments such as β-carotene, α-toco- lipophilic antioxidants to be work- ic diseases related to aging, such as pherol and/or multivitamins.