Datasheet Version: 1.0.0 Revision date: 02 Nov 2020

Malate Dehydrogenase 2 (MDH2) Antibody Catalogue No.:abx004812

Western blot analysis of extracts of various cell lines, using MDH2 antibody (abx004812) at 1/1000 dilution.

Immunohistochemistry of paraffin-embedded human liver injury using MDH2 Antibody (abx004812) at dilution of 1/100 (40x lens).

Immunohistochemistry of paraffin-embedded human liver injury using MDH2 Antibody (abx004812) at dilution of 1/100 (40x lens).

Immunohistochemistry of paraffin-embedded human leiomyoma of uterus using MDH2 Antibody (abx004812) at dilution of 1/100 (40x lens). For Reference Only

MDH2 Antibody is a Rabbit Polyclonal antibody against MDH2. catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene.

v1.0.0 Abbexa Ltd, Cambridge, UK · Phone: +44 1223 755950 · Fax: +44 1223 755951 1 Abbexa LLC, Houston, TX, USA · Phone: +1 832 327 7413 www.abbexa.com · Email: [email protected] Datasheet Version: 1.0.0 Revision date: 02 Nov 2020

Target: MDH2

Clonality: Polyclonal

Reactivity: Human, Mouse

Tested Applications: WB, IHC

Host: Rabbit

Recommended dilutions: WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.

Conjugation: Unconjugated

Immunogen: Recombinant protein of human MDH2.

Isotype: IgG

Form: Liquid

Purification: Affinity purified.

Storage: Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

UniProt Primary AC: P40926 (UniProt, ExPASy)

Gene Symbol: MDH2

GeneID: 4191

KEGG: hsa:4191

String: 9606.ENSP00000327070

Molecular Weight:ForCalculated Reference MW: 30 kDa, 35 kDa Only Observed MW: 35 kDa

Buffer: PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.

Concentration: > 1 mg/ml

Note: This product is for research use only.

v1.0.0 Abbexa Ltd, Cambridge, UK · Phone: +44 1223 755950 · Fax: +44 1223 755951 2 Abbexa LLC, Houston, TX, USA · Phone: +1 832 327 7413 www.abbexa.com · Email: [email protected]