FOSL2 Antibody Cat. No.: 55-535
FOSL2 Antibody
FOSL2 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human lung Western blot analysis in CHO cell line lysates (35ug/lane). carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.
Specifications
HOST SPECIES: Rabbit
SPECIES REACTIVITY: Hamster, Human
HOMOLOGY: Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Rat
This FOSL2 antibody is generated from rabbits immunized with a KLH conjugated IMMUNOGEN: synthetic peptide between 95-122 amino acids from the Central region of human FOSL2.
TESTED APPLICATIONS: IHC-P, WB
For WB starting dilution is: 1:1000 APPLICATIONS: For IHC-P starting dilution is: 1:50~100
September 27, 2021 1 https://www.prosci-inc.com/fosl2-antibody-55-535.html PREDICTED MOLECULAR 35 kDa WEIGHT:
Properties
This antibody is purified through a protein A column, followed by peptide affinity PURIFICATION: purification.
CLONALITY: Polyclonal
ISOTYPE: Rabbit Ig
CONJUGATE: Unconjugated
PHYSICAL STATE: Liquid
BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
CONCENTRATION: batch dependent
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
OFFICIAL SYMBOL: FOSL2
ALTERNATE NAMES: Fos-related antigen 2, FRA-2, FOSL2, FRA2
ACCESSION NO.: P15408
PROTEIN GI NO.: 120487
GENE ID: 2355
USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background and References
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby BACKGROUND: forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
REFERENCES: 1) Bozec, A., et al. J. Cell Biol. 190(6):1093-1106(2010)
2) Bolat, I., et al. Folia Histochem. Cytobiol. 48(2):197-201(2010)
3) Reich, N., et al. Arthritis Rheum. 62(1):280-290(2010)
4) Maurer, B., et al. Circulation 120(23):2367-2376(2009)
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