2019 Korean Society of Hematology International Conference & 60 th Annual Meeting

March 14 – 16, 2019 | Grand Walkerhill Hotel, Seoul, Korea www.icksh.org

• Name: Hirotaka Matsui

• Current Position: Professor, Department of Molecular Laboratory Medicine, University, .

• Country: Japan

• Educational Background: 2003. Ph.D. Graduate School of University School of Medicine, Japan 1995. MD. Hamamatsu University School of Medicine, Japan

• Professional Experiences: Professor 2015 - present Department of Molecular Laboratory Medicine, , Japan. Laboratory Director 2015 – present Department of Laboratory Medicine and Transfusion Medicine, Kumamoto University Hospital Associate Professor 2010 - 2015 Assistant Professor 2004-2010 Postdoctoral Fellow 2003-2004 Research Institute for Radiation Biology and Medicine University, Japan Graduate Student 1999 - 2003 Third Department of Internal Medicine, Hamamatsu University School of Medicine, Japan Resident Seirei Hamamatsu Hospital, Japan. 1998-1999. Hamamatsu Medical Center, Japan.1996-1998. Third Department of Internal Medicine, Hamamatsu University School of Medicine, Japan 1995 - 1996

2019 Korean Society of Hematology International Conference & 60 th Annual Meeting

March 14 – 16, 2019 | Grand Walkerhill Hotel, Seoul, Korea www.icksh.org

• Professional Organizations Japanese Society of Hematology (Councilor, board-certified specialist) Japanese Society of Laboratory Medicine (Councilor, board-certified specialist) Japanese Society of Internal Medicine Japanese Cancer Association American Society of Hematology International Society of Experimental Hematology

 Main Scientific Publications:

1. Inaba T, Honda H, Matsui H. The enigma of monosomy 7. Blood 131(26), 2891-2898, 2018.

2. Sasada K, Yamamoto N, Masuda H, Tanaka Y, Ishihara A, Takamatsu Y, Yatomi Y, Katsuda W, Sato I, Matsui H. Inter-observer variance and the need for standardization in the morphological classification of myelodysplastic syndrome . Leuk Res. 69, 54-59, 2018.

3. Inoue D, Fujino T, Sheridan P, Zhang YZ, Nagase R, Horikawa S, Li Z, Matsui H, Kanai A, Saika M, R, Kozuka-Hata H, Kawabata KC, Yokoyama A, Goyama S, Inaba T, Imoto S, Miyano S, Xu M, Yang FC, Oyama M, Kitamura T. A novel ASXL1-OGT axis plays roles in H3K4 methylation and tumor suppression in myeloid malignancies. Leukemia 32(6), 1327-1337, 2018.

4. Okuda H, Stanojevic B, Kanai A, Kawamura T, Takahashi S, Matsui H, Takaori- Kondo A, Yokoyama A. Cooperative gene activation by AF4 and DOT1L drives MLL-rearranged leukemia. J. Clin. Invest . 127(5): 1918-1931, 2017.

5. Sugino N, Kawahara M, Tatsumi G, Kanai A, Matsui H, Yamamoto R, Nagai Y, Fujii S, Shimazu Y, Hishizawa M, Inaba T, Andoh A, Suzuki T, Takaori-Kondo A. A novel LSD1 inhibitor NCD38 ameliorates MDS-related leukemia with complex karyotype by attenuating leukemia programs via activating super- enhancers. Leukemia 31(11), 2303-2314, 2017.