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PROFESSIONALISM AND LEADERSHIP 2017 ADVANCING EDUCATIONAL SCIENCE EXCELLENCE COMMUNITY CLINICAL COMMITMENT & INNOVATION ENGAGEMENT ACADEMIC UPDATE Department of Psychiatry and Behavioral Sciences Contents Message from the Chair 3 Advancing Science 49 Major Laboratories: Exemplars 50 4 Faculty Research Highlights 52 Department Overview Active Sponsored Research 121 Department Sources of Research Funding 133 8 2016 Brain & Mind Summit 134 Department Snapshot Department Small Grants Program 135 10 Professionalism and Leadership Educational Excellence 138 Department Leadership Team 12 Department Education Programs 139 Departmental Advisory Committees 14 Featured Works 146 Administration 16 Department Faculty 18 Professoriate Retirements 36 Clinical Innovation and Service 153 Academic Update Team Faculty Honors 37 Annual Chairman’s Awards 38 University Engagement 154 Executive Editor Community Commitment and 156 Model of Academic Excellence 40 Laura Roberts, MD, MA Engagement Community Outreach Efforts: Exemplars 158 Designer Department Structure 42 Department Locations 168 Megan Cid Divisions of the Department 44 Special Initiatives of the Chair 171 Copy Editors Ann Tennier Eric Termuehlen The information presented in this update represents data as of March 1, 2017. psychiatry.stanford.edu Advancing Science Message from the Chair Together we are creating a new paradigm for modern psychiatry. This transformational approach to psychiatry at Stanford differs in its intention, which moves beyond understanding and eradicating disease toward the imperative of fostering health, resilience, and wellbeing. This transformational new psychiatry differs in that it is much more richly informed by extraordinary scientific discoveries and, at the same time, by an appreciation of the ancient role of the therapeutic relationship in human healing. Our approach to psychiatry is driven by innovation -- combining novel approaches and technologies to tackle the hardest challenges in the laboratory, clinic, and community. Our transformational new approach exists because of the acceleration of work by scientists, scholars, educators and learners in many academic disciplines. Rapidly translating great science and dismantling societal barriers, our work seeks to revolutionize standards of care for millions of people burdened by mental disorders. This is an expression of Precision Health and Wellness, the strategic vision of Stanford Medicine, and it is ambitious. We are transforming Together, we are creating human health. We have arrived at this moment because of the creativity, tenacity, and clarity of purpose of our academic community. We all have a role in advancing science, clinical innovation and service, educational excellence, a new paradigm for community commitment and engagement, and professionalism and leadership. These missions, taken together, become a transformative methodology and have become the basis of The Transformational New modern psychiatry. Psychiatry at Stanford. Laura Roberts, M.D., M.A. Chairman and Katharine Dexter McCormick and Stanley McCormick Memorial Professor Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine 2 3 Psychiatry and Behavioral Sciences of Stanford Medicine Academic medicine is entrusted with improving the health of individuals, Academic medicine communities, and populations. And in academic psychiatry and the is entrusted with behavioral sciences, we have a special responsibility to advance understanding of the nature of the brain and of behavior and to explore human health. the role of personal meaning and the therapeutic relationship in human health -- not only to lessen the burden of disease in the world but also to foster wellbeing, resilience and strengths for generations to come. Our aim is to enable great science, prepare great people, Building on the remarkable accomplishments of the past, together we Together we have established a great modern academic department, integrating and and inspire a great society to create a better future for all have created a accelerating our five missions of advancing science, clinical innovation and service, educational excellence, community engagement and whose lives are affected by mental illness. truly distinguished commitment, and professionalism and leadership. And together we department. are making a difference in the lives of our patients, our students, our neighborhood, and our world. It is my privilege to serve with you in leading this department. With deep respect and my heartfelt thanks to my The Department of Psychiatry and Behavioral Sciences of Stanford Medicine has a great tradition of colleagues throughout our department, I offer these reflections on what is fundamental science, translational and clinical research, subspecialty expertise, multidisciplinary education, distinct about our academic home. and influential leadership. Our faculty members are highly accomplished scientists, master clinicians, teachers, and community-engaged leaders with transformative impact across many disciplines of science, medicine, and health policy. Our work spans and integrates five interdependent academic missions of advancing science, clinical innovation and service, educational excellence, community commitment and engagement, and professionalism and leadership. We are a community dedicated to transformational change and social Advancing truly transformative science of significance to human health, now and in the future, is clearly Stanford Our department good. We understand the impact of mental illnesses, which are the Medicine’s most important role throughout the world. The capacity of our department – one of the largest at is inspired. second leading cause of disability and premature mortality globally, and Stanford University – to conduct great science and to connect this creative and influential work with our other we are deeply affected by the immense suffering and social injustices academic missions is what distinguishes us and continues to inspire us. associated with these conditions. We see that the path to health for people and populations is enabled by creating and applying new knowledge, by The overarching aim of creating a better future is predicated on our shared pursuit of discovery across the engaging in innovation, and by preparing future generations of scientists basic, translational, clinical, and population sciences. This aim is also predicated on our collaborative efforts and clinicians. Each of us, whether faculty, learner, or staff, is passionate to translate and back-translate new knowledge in our training of scientists and expert clinicians, in supporting about our work because we recognize its vital importance to humanity -- the careers of outstanding faculty and learners, and in addressing the needs of communities, local and global. to all of our health and futures. Moreover, if we are to ensure that clinical care today at Stanford – and ten years from now throughout the world – leads to far better health outcomes, scientific discovery must be expressed in new approaches to prevention, new therapeutics, and new models of care. 4 5 We aim to cure mental illness. We advance understanding of the We are a network of scientists, clinicians, educators, trainees, and Our department body’s most complex organ, the brain: its biological underpinnings, its Our department staff with the shared intent to make a difference through our efforts takes on the functions, its development, its plasticity, its regulation, its dysfunction, makes connections in science, clinical care, education, the community, and leadership. its vulnerabilities, its aging, and its resilience. We study cognition, We form research collaborations across the Stanford campus, we hardest problems. behavior, emotion, and relationships. We use this knowledge to develop and works participate in and lead professional organizations, we teach at every evidence-based treatments, and with compassion and expertise we care level in the university, and we lecture internationally. As educators, for individuals living with prevalent, severe, and often highly treatment- shoulder to we endeavor to bring forward the best in our gifted students resistant conditions. Our work informs clinical practices, systems of care, through mentorship and rich collaborative learning experiences. We and health policy to reduce disability, loss of life, and stigma. We do not shoulder. provide care in all parts of Stanford Medicine, with its continuum of turn away from the hardest problems. Instead we move toward them. We care, outreach activities, and civic responsibilities. We join public understand that resolving the hardest problems will make the greatest health efforts in Palo Alto and across the globe. We work together, difference. shoulder to shoulder, making intentional connections across the five interdependent missions of the department, as the prime strategy for transformative change. Our scientists develop highly innovative approaches to discovery at Our department is home to leaders, innovators, and learners Our department every level in the clinical and behavioral neurosciences, thereby exerting Our department creating the path to a better future. The attributes that distinguish is a hothouse of scientific leadership throughout the world. In our laboratories, the is creating the the department are many, and I have highlighted just a few. Being molecular, cellular, and circuit mechanisms of mental disorders are being inspired, creative, and collaborative. Being drawn