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Effect of Maternal Anaemia on APGAR Score of Newborn

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Effect of Maternal Anaemia on APGAR Score of Newborn Journal of Rawalpindi Medical College (JRMC); 2015;19(3):239-242 Original Article Effect of Maternal Anaemia on APGAR Score of Newborn Muhammad Owais Ahmad1, Umay Kalsoom 2 1.Department of Physiology, HBS Medical & Dental College Islamabad;2.Department of Community Medicine, Foundation University Medical College Rawalpindi, Abstract probability of low APGAR score at one and five minutes. Background: To study the effect of maternal anaemia on APGAR score of newborn and to Key Words: Maternal Anaemia, Apgar score, compare it with that of non-anaemic mothers. Pregnancy. Methods: In this cross sectional study 100 subjects were divided into two groups; each containing 50 Introduction subjects on the basis of consecutive non probability Anaemia is a common medical problem in pregnancy sampling . Group A included 50 anaemic pregnant and maternal anaemia is commonly considered a risk women (haemoglobin < 11.0 g/dl) and group B 50 factor for poor pregnancy outcome. Fetal morbidity non-anaemic(haemoglobin >11.0 g/dl) pregnant and mortality is also increased by maternal anaemia women. In APGAR scoring five factors (which by increasing the chances of preterm delivery and low Apgar stands for) were used to calculate the baby’s birth weight of the babies. Infants are so compromised condition and each scored on a scale of 0 to 2, with 2 that they are born with low APGAR score at both 1 being the best score.A baby who scored 8 or above and 5 minutes after delivery. Though in some studies was considered in good health and a score of less an association between maternal anaemia and lower than 8 was considered low. Data was compared infant Apgar scores was reported, but it is still unclear using t-test at a confidence level of 95%. Frequencies to what extent maternal anaemia affects maternal and were calculated for categorical data. These were neonatal health, as there is variation in the data from compared using chi-square test, and p<0.05 was different studies. Anaemia is a state where the statistically significant. delivery of oxygen to the tissues is impaired because Results: Difference between the two groups was of a quantitative or qualitative deficiency of haemoglobin or red blood cells.1 Anaemia is a found to be statistically very significant (p<0.003)in widespread issue in pregnancy.2 Anaemia is found in this variable also, as 16 out of 50 babies delivered to upto half of pregnant women in developing countries mothers in the anemic group showed a low APGAR and almost 1/5th of the maternal deaths in pregnancy at one minute as against 04 out of 50 in the babies are either directly or indirectly related to anaemia. As delivered to the mothers in the non anemic group per W.H.O Haemoglobin concentration of less than 11 .Difference between the two groups was found to be gm/ dl and haematocrit of < 0-33 is declared as statistically significant (p<0.012) . Twelve out of 50 anaemia in pregnancy.3,4 babies delivered to mothers in the anemic group in Anaemia is a crucial health concern as it affects growth our study showed a low APGAR at five minutes as and development of neonates. Prevalence of anaemia against 03 out of 50 in the babies delivered to the in developing countries is upto 56%.5,6 Anaemia not mothers in the non anemic group.The number of only results in maternal morbidity and mortality and anemic mothers who showed a low APGAR score of affects the perinatal outcome, it can also cause their infants were more at both one (32%) and five maternal infections, post partum haemorrhage and minutes (24%) as compared to the non anemic group pre-eclampsia. Body aches and easy fatigability are (08% and 06% respectively), with a statistically common symptoms in anaemic pregnant women. highly significant difference of these two variables Some researches believe that the relationship of (p<0.003 and p<0.01 respectively) between the two maternal mortality with anaemia is more because of groups. haemorrhage and late admission instead of a prenatal Conclusion: There was a linear relationship of anaemic condition. Fetal morbidity and mortality is maternal anaemia in pregnancy with greater also more common with maternal anaemia by 239 Journal of Rawalpindi Medical College (JRMC); 2015;19(3):239-242 increasing the chances of preterm delivery and low Data was compared using t-test at a confidence level birth weight of the babies. Infants are so compromised of 95%. Frequencies were calculated for categorical that they are born with low APGAR score at both 1 data. These were compared using chi-square test, and and 5 minutes after delivery. p<0.05 was statistically significant. Despite the advent of modern technology, the APGAR score which is the first test given to a baby just after Table 1:Apgar Scoring: birth in the delivery room remains the best tool for the Sign Score identification of newly born infants in need of 2 1 0 cardiopulmonary resuscitation. An association A Appearance Normal Normal Cyanotic between maternal anemia and lower infant Apgar (skin colour) over entire except or pale all scores was reported in some studies. In 102 Indian body extremities over women in the first stage of labor, higher maternal P Pulse(heart rate) >100 bpm <100bpm Absent G Grimace Sneezes, Grimaces No hemoglobin concentrations were correlated with better response(refle coughs, response APGAR scores and with a lower risk of birth xes) pulls 7 asphyxia. When pregnant women were treated with away iron or a placebo in Niger, APGAR scores were A Activity Active Arms and Absent significantly higher in those infants whose mothers (muscle tone) legs flexed received iron.8 There is variation in the data from R Respiration Good, Slow, Absent different studies about the association of maternal (breathing rate crying irregular anemia on adverse pregnancy outcomes and there is and effort) insufficient information to assess the overall adverse impact of anemia during pregnancy. Results Difference between the two groups was found to be Patients and Methods statistically very significant (p<0.003)in this variable The study design was cross-sectional, comparing the also, as 16 out of 50 babies delivered to mothers in the effect of maternal anaemia on APGAR score of the anaemic group in our study showed a low APGAR at baby with that of non-anaemic mothers. This study one minute as against 04 out of 50 in the babies took place at Maternity Unit of Fauji Foundation delivered to the mothers in the non anemic group Hospital, Rawalpindi during the year 2009. Sample (Table 2). size was 100 divided into two groups each containing Table 2: Comparison of the number of babies 50 subjects. Group-A included 50 anaemic with low APGAR score at 1 minute of the (haemoglobin <11.0 g/dl) pregnant women and mothers in the anaemic and non anaemic groups Group-B 50 non-anaemic (haemoglobin >11.0 g/dl) Group Yes No pregnant women. Samples were collected by A, Anaemic (n=50) 16 34 consecutive non-probability. Inclusion criteria was all B, Non Anaemic (n=50) 04 46 pregnant women 16 years and older and a singleton P-Value 0.003** pregnancy with a complete medical record. All **p = Significant women with a past history of preterm delivery, obstetrical complications or any medical illness, except Table 3: Comparison of the number of babies anaemia, were excluded from the study for control of with low APGAR score at 5 minutes of the the confounding factors. Information was collected by mothers in the anaemic and non anaemic groups direct interviewing method through questionnaire. Group Yes No Haemoglobin was estimated on automated A, Anaemic (n=50) 12 38 haematology analyzer and APGAR score was B, Non Anaemic (n=50) 03 47 calculated according to standard format (Table 1). In p-Value 0.012** APGAR scoring five factors (which APGAR stands **p = Significant for) were used to calculate the baby’s condition and each scored on a scale of 0 to 2, with 2 being the best Difference between the two groups was found to be score statistically significant (p<0.012) in our study as 12 out A baby who scored 8 or above was considered in good of 50 babies delivered to mothers in the anaemic group health and a score of less than 8 was considered low. in our study showed a low APGAR at five minutes as 240 Journal of Rawalpindi Medical College (JRMC); 2015;19(3):239-242 against 03 out of 50 in the babies delivered to the study, with a highly significant difference from the mothers in the non anaemic group (Table 3). The non anemic group (p - 0.003). Our study results are number of anaemic mothers who showed a low consistent with the findings of Lone et al15 who found APGAR score of their infants were more at both one that maternal anemia is associated with a 2.1 times (32%) and five minutes (24%) as compared to the non increased risk (95% CI = 1.2-3.7) of APGAR score of <5 anaemic group (08% and 06% respectively), with a at one minute, in a univariate analysis of their study statistically highly significant difference of these two population. Our results were also consistent with a variables (p<0.003 and p<0.01 respectively) between recent study which was conducted in El Sahel the two groups. Teaching Hospital, Cairo, Egypt, in which subjects were divided into severely anemic, mildly anemic and Discussion non-anemic categories. In this study the comparisons Anaemia of pregnancy can have short-term and far- between pregnancy outcomes in the three groups reaching sequelae for the newborn.9 Although anemia showed a statistically significant difference between is a common problem in pregnant women in gestational age, birth weight, birth length and Apgar developing countries, pregnancy outcomes vary score on one hand and the degree of anemia on the 16 depending upon the type of anaemia.
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