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The Pharmacologist 2 0 0 6 December
Vol. 48 Number 4 The Pharmacologist 2 0 0 6 December 2006 YEAR IN REVIEW The Presidential Torch is passed from James E. Experimental Biology 2006 in San Francisco Barrett to Elaine Sanders-Bush ASPET Members attend the 15th World Congress in China Young Scientists at EB 2006 ASPET Awards Winners at EB 2006 Inside this Issue: ASPET Election Online EB ’07 Program Grid Neuropharmacology Division Mixer at SFN 2006 New England Chapter Meeting Summary SEPS Meeting Summary and Abstracts MAPS Meeting Summary and Abstracts Call for Late-Breaking Abstracts for EB‘07 A Publication of the American Society for 121 Pharmacology and Experimental Therapeutics - ASPET Volume 48 Number 4, 2006 The Pharmacologist is published and distributed by the American Society for Pharmacology and Experimental Therapeutics. The Editor PHARMACOLOGIST Suzie Thompson EDITORIAL ADVISORY BOARD Bryan F. Cox, Ph.D. News Ronald N. Hines, Ph.D. Terrence J. Monks, Ph.D. 2006 Year in Review page 123 COUNCIL . President Contributors for 2006 . page 124 Elaine Sanders-Bush, Ph.D. Election 2007 . President-Elect page 126 Kenneth P. Minneman, Ph.D. EB 2007 Program Grid . page 130 Past President James E. Barrett, Ph.D. Features Secretary/Treasurer Lynn Wecker, Ph.D. Secretary/Treasurer-Elect Journals . Annette E. Fleckenstein, Ph.D. page 132 Past Secretary/Treasurer Public Affairs & Government Relations . page 134 Patricia K. Sonsalla, Ph.D. Division News Councilors Bryan F. Cox, Ph.D. Division for Neuropharmacology . page 136 Ronald N. Hines, Ph.D. Centennial Update . Terrence J. Monks, Ph.D. page 137 Chair, Board of Publications Trustees Members in the News . -
Physiological Studies of the Vestibulosympathetic Reflex in Humans
! ! ! Physiological Studies of the Vestibulosympathetic Reflex in Humans Elie Hammam, BMedSci (Hons I) School of Medicine University of Western Sydney Supervisor Prof. Vaughan Macefield Co-Supervisor Prof. Kenny Kwok A thesis submitted to the University of Western Sydney in candidature for the award of Doctor of Philosophy, 2014 ! ! "! ! ! ! STATEMENT OF AUTHENTICATION I, Elie Hammam, declare that this thesis is based entirely on my own independent work, except for sections which were performed in collaboration with colleagues as acknowledged in the study and resulted in the publication of the journal articles shown below. To the best of my knowledge this project does not contain material previously submitted in fulfillment of the guidelines and requirements for the award of Doctor of Philosophy in the School of Medicine, University of Western Sydney, and has not been submitted for qualifications at any other academic institution. Elie Hammam ! ! ! ! #! ! ! ! ACKNOWLEDGEMENTS Undertaking the highest scholarly exercise a University offers has certainly been a long, arduous, but nevertheless a fulfilling journey. Now completed, reflection has allowed me to appreciate that what I have achieved is merely a credit to my efforts. I am deeply indebted to the guidance of my mentors, encouragements from friends and support from family. First and foremost, I wish to acknowledge my stellar supervisor Vaughan Macefield who has never shied from supporting me throughout my candidature. Vaughan, from the very beginning you believed in me and never ceased to impart your knowledge, skills and wisdom. You have ensured all throughout my candidature that I get a holistic development in preparation to a life with academic excellence. -
Assessment of Traumatic Nerve Injuries
American Association of Neuromuscular & Electrodiagnostic Medicine AANEM ASSESSMENT OF TRAUMATIC NERVE INJURIES Lawrence R. Robinson, MD Jeffrey G. Jarvik, MD, MPH David G. Kline, MD 2005 AANEM COURSE G AANEM 52nd Annual Scientific Meeting Monterey, California Assessment of Traumatic Nerve Injuries Lawrence R. Robinson, MD Jeffrey G. Jarvik, MD, MPH David G. Kline, MD 2005 COURSE G AANEM 52nd Annual Scientific Meeting Monterey, California AANEM Copyright © September 2005 American Association of Neuromuscular & Electrodiagnostic Medicine 421 First Avenue SW, Suite 300 East Rochester, MN 55902 PRINTED BY JOHNSON PRINTING COMPANY, INC. ii Assessment of Traumatic Nerve Injuries Faculty Lawrence R. Robinson, MD David G. Kline, MD Professor Boyd Professor and Head Department of Rehabilitation Medicine Department of Neurosurgery University of Washington Louisiana State University Medical Center Seattle, Washington New Orleans, Louisiana Dr. Robinson attended Baylor College of Medicine and completed his res- Dr. Kline is currently a Boyd Professor and Head of the Department of idency training in rehabilitation medicine at the Rehabilitation Institute of Neurosurgery at Louisiana State University (LSU) Medical Center in New Chicago. He now serves as professor and chair of the Department of Orleans. He earned his medical degree from the University of Rehabilitation Medicine at the University of Washington and is the Pennsylvania, then performed his internship at the University of Michigan. Director of the Harborview Medical Center Electrodiagnostic Laboratory. He performed residencies at the University of Michigan and Walter Reed He is also currently Vice Dean for Clinical Affairs at the University of General Hospital and Institute of Research. Dr. Kline has served on sever- Washington. -
Late Calcium EDTA Rescues Hippocampal CA1 Neurons from Global Ischemia-Induced Death
The Journal of Neuroscience, November 3, 2004 • 24(44):9903–9913 • 9903 Neurobiology of Disease Late Calcium EDTA Rescues Hippocampal CA1 Neurons from Global Ischemia-Induced Death Agata Calderone, Teresa Jover,* Toshihiro Mashiko,* Kyung-min Noh, Hidenobu Tanaka,† Michael V. L. Bennett, and R. Suzanne Zukin Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York 10461 Transient global ischemia induces a delayed rise in intracellular Zn 2ϩ, which may be mediated via glutamate receptor 2 (GluR2)-lacking AMPA receptors (AMPARs), and selective, delayed death of hippocampal CA1 neurons. The molecular mechanisms underlying Zn 2ϩ toxicity in vivo are not well delineated. Here we show the striking finding that intraventricular injection of the high-affinity Zn 2ϩ chelator calcium EDTA (CaEDTA) at 30 min before ischemia (early CaEDTA) or at 48–60 hr (late CaEDTA), but not 3–6 hr, after ischemia, afforded robust protection of CA1 neurons in ϳ50% (late CaEDTA) to 75% (early CaEDTA) of animals. We also show that Zn 2ϩ acts via temporally distinct mechanisms to promote neuronal death. Early CaEDTA attenuated ischemia-induced GluR2 mRNA and protein downregulation (and, by inference, formation of Zn 2ϩ-permeable AMPARs), the delayed rise in Zn 2ϩ, and neuronal death. These findings suggest that Zn 2ϩ acts at step(s) upstream from GluR2 gene downregulation and implicate Zn 2ϩ in transcriptional regulation and/or GluR2 mRNA stability. Early CaEDTA also blocked mitochondrial release of cytochrome c and Smac/DIABLO (second mitochondria-derived activator of caspases/direct inhibitor of apoptosis protein-binding protein with low pI), caspase-3 activity (but not procaspase-3 cleavage), p75 NTR induction, and DNA fragmentation. -
The Role of Sympathetic Nervous Activity in Chronic Renal Failure
Journal of Clinical and Basic Cardiology An Independent International Scientific Journal Journal of Clinical and Basic Cardiology 2001; 4 (3), 179-182 The Role of Sympathetic Nervous Activity in Chronic Renal Failure Rump LC Homepage: www.kup.at/jcbc Online Data Base Search for Authors and Keywords Indexed in Chemical Abstracts EMBASE/Excerpta Medica Krause & Pachernegg GmbH · VERLAG für MEDIZIN und WIRTSCHAFT · A-3003 Gablitz/Austria FOCUS ON SYMPATHETIC TONE Sympathetic Overactivity in Chronic Renal Failure J Clin Basic Cardiol 2001; 4: 179 The Role of Sympathetic Nervous Activity in Chronic Renal Failure L. C. Rump Cardiovascular morbidity and mortality are extremely high in patients with chronic renal failure. Preventing progression of chronic renal failure and reducing the cardiovascular risk of uraemic patients are major challenges for nephrologists. In the past the renin-angiotensin system has been the main focus of research and therapy efforts. Today we know that sympathetic over- activity plays an important role for progression and prognosis in chronic renal disease. Afferent signals arising from the dam- aged kidneys due to the activation of mechanoreceptors and chemoreceptors lead to efferent sympathetic nervous activation. This results in an enhanced release of the sympathetic neurotransmitters noradrenaline, ATP and NPY at important neuro- effector junctions in heart, kidney and blood vessels. All three sympathetic cotransmitter are able to induce vasoconstriction and to stimulate proliferative processes. Recently it was shown in an animal model of chronic renal failure that inhibition of sympa- thetic nervous activity by moxonidine ameliorates disease progression. This effect was independent from blood pressure reduc- tions and likely due to reduced cotransmitter release. -
Department of Neuroscience Faculty Research Interests at the Albert Einstein
Dominick P. Purpura Department of Neuroscience Faculty Research Interests at the Albert Einstein DOBRENIS EMMONS ESKANDER COEN-CAGLI College of Medicine FISHMAN CHUA FRANCESCONI CASTILLO 2019–2020 FRENETTE BUSCHKE FRICKER GALANOPOULOU BUELOW GONÇALVES BERGMAN HALL BENNETT HÉBERT BATISTA-BRITO JORDAN BALLABH KHODAKHAH AUTRY ASCHNER AREZZO KURSHAN ALPERT AKABAS LACHMAN LAROCCA LEGATT LIPTON MEHLER MOLHOLM MOSHÉ NICOLA PEÑA PEREDA ROSS RUDOLPH SCHWARTZ SECOMBE SHARP SINGER SJULSON SOLDNER SPRAY STEINSCHNEIDER SUADICANI SUSSMAN VERSELIS WALKLEY WILSON YANG ZHENG ZUKIN Dominick P. Purpura Department of Neuroscience Faculty Research Interests at the Albert Einstein College of Medicine 2019–2020 Myles Akabas, M.D., Ph.D. 1 Peri Kurshan, Ph.D. 68 Joseph C. Arezzo, Ph.D. 6 Herbert M. Lachman, M.D. 70 Michael Aschner, Ph.D. 8 Jorge N. Larocca, Ph.D. 73 Anita E. Autry, Ph.D. 10 Alan D. Legatt, M.D., Ph.D. 75 Praveen Ballabh, M.D. 12 Michael L. Lipton, M.D., Ph.D. 77 Renata Batista-Brito, Ph.D. 14 Mark F. Mehler, M.D. 81 Michael V. L. Bennett, D.Phil. 16 Sophie Molholm, Ph.D. 83 Aviv Bergman, Ph.D. 18 Solomon L. Moshé, M.D. 89 Herman Buschke, M.D. 24 Saleem M. Nicola, Ph.D. 93 Pablo E. Castillo, M.D., Ph.D. 25 José L. Peña, M.D., Ph.D. 96 Streamson C. Chua, Jr., M.D., Ph.D. 27 Alberto E. Pereda, M.D., Ph.D. 98 Ruben Coen-Cagli, Ph.D. 29 Rachel A. Ross, M.D., Ph.D. 100 Kostantin Dobrenis, Ph.D. 31 Stephanie Rudolph, Ph.D. 102 Scott W. -
The Pharmacologist December
Vol. 55 Number 4 2013 The Pharmacologist December Also in this issue: • 2013 Year in Review • 2013 Contributors • 2014 Election Nominees • Program grid for ASPET Annual Meeting at EB 2014 • Holiday Gift Ideas for Pharmacologists • Meet the 2014 Washington Fellows • MAPS Chapter Meeting abstracts (online only) Katharine Dexter McCormick (Courtesy of the Santa Barbara Historical Museum) The Pharmacologist is published and distributed by the American Society for Pharmacology and Experimental Therapeu cs. Contents THE PHARMACOLOGIST PRODUCTION TEAM NEWS Gary Axelrod President's Corner 193 Suzie Thompson Judith A. Siuciak, Ph.D. 2013 Year in Review 194 Richard Dodenhoff 2013 Contributors 196 Danielle Jordan 2013 Corporate Contributors 197 COUNCIL 2014 Elec on Nominees 198 President Richard R. Neubig, M.D., Ph.D. ASPET Annual Mee ng at EB 2014 President-Elect Program Grid 200 Anne e E. Fleckenstein, Ph.D. Past President Important Dates, Informa on, and Links 202 John S. Lazo, Ph.D. Holiday Gi s for Pharmacologists 204 Secretary/Treasurer Sandra P. Welch, Ph.D. FEATURE Secretary/Treasurer-Elect Katharine Dexter McCormick and the Pill Paul A. Insel, M.D. by Rebecca J. Anderson, Ph.D. 206 Past Secretary/Treasurer Edward T. Morgan, Ph.D. DEPARTMENTS Councilors Journals 214 Charles P. France, Ph.D. Science Policy 215 John D. Schuetz, Ph.D. Kenneth E. Thummel, Ph.D. Social Media 221 Chair, Board of Publica ons Trustees Book Review: S ff : The Curious Lives of Human Cadavers 222 James E. Barre , Ph.D. Chair, Program Commi ee In the Spotlight: Interviews with ASPET Members 223 Sco Waldman, M.D., Ph.D. -
TLN Agenda-101507
Fall 2007 Janelia Conference: Translation at the Synapse Full Schedule Sunday, October 21st 3:00 pm Check-in 6:00 pm Reception 7:00 pm Dinner 8:00 pm Session 1 (chair - Kevin Moses) 8:00 pm Oswald Steward, University of California, Irvine Mechanisms underlying the selective localization of Arc mRNA at active synapses 8:30 pm James Eberwine, University of Pennsylvania School of Medicine Molecular Biology of the Neuronal Dendrite 9:00 pm Robert Singer, Albert Einstein College of Medicine Following single mRNAs from birth to translation 9:30 pm Erin Schuman, California Institute of Technology/HHMI Visualization of dendritic protein synthesis 10:00 pm Refreshments available at Bob’s pub Fall 2007 Janelia Conference: Translation at the Synapse Monday, October 22nd 7:30 am Breakfast 8:30 am Session 2 (chair - Erin Schuman) 8:30 am Michael Kiebler, Medical University of Vienna The role of Staufen in dendritic RNP transport and dendritic spine morphogenesis 9:00 am Nobutaka Hirokawa, University of Tokyo Intracellular transport of mRNA and kinesin superfamily proteins, KIFs 9:30 am Mark F. Bear, Massachusetts Institute of Technology/HHMI Fragile X syndrome: A disease of synaptic protein synthesis 10:00 am Suzanne Zukin, Albert Einstein College of Medicine AMPA receptor mRNA trafficking in dendrites and synaptic plasticity: dysregulation in Fragile X 10:30 am Break and Group Photo 11:00 am Gary J. Bassell, Emory University School of Medicine Dysregulated mGluR-dependent translation of AMPA receptor and PSD- 95 mRNAs in fragile x syndrome 11:30 am Tom Jongens, University of Pennsylvania School of Medicine Regulation of the Drosophila Fragile X mental retardation gene by the siRNA pathway 12:00 pm Claudia Bagni, University of Rome Translational control at synapses and mental retardation: new insights into the Fragile X Syndrome 12:30 pm Lunch 1:00 pm Tour 2:00 pm Session 3 (chair - Mark F. -
Wang-Cv-July2017.Pdf
CURRICULUM VITAE Samuel Sheng-Hung Wang, Ph.D. Born: May 4, 1967 Address: Neuroscience Institute, Princeton University, Princeton, NJ 08544 Telephone: (609) 258-0388 FAX: (609) 258-1028 E-mail: sswang [at] princeton.edu Web: http://synapse.princeton.edu Research interests 1) Neuroscience – integrative role of the cerebellum in sensory learning and autism 2) Optical methods for observing and manipulating living brain tissue 3) Statistical analysis of data in neuroscience, development, and politics Education 1980-1982 Riverside Poly High School, Riverside, California 1982-1986 B.S. with honor, Physics, California Institute of Technology 1986-1993 Ph.D., Neurosciences, Stanford University (advisor: Stuart H. Thompson) Professional positions 1994-1995, 1996-1997 Postdoctoral fellow, Duke University (with George J. Augustine) 1995-1996 Congressional Science Fellow, Senate Committee on Labor and Human Resources (with Senator Edward M. Kennedy) 1997-1999 Postdoctoral Member of Technical Staff, Biological Computation Res. Dept., Bell Labs Lucent Technologies (with David W. Tank and Winfried Denk) 2000-2006 Assistant Professor, Department of Molecular Biology, Princeton University 2006-2015 Associate Professor, Department of Molecular Biology and Princeton Neuroscience Institute, Princeton University 2013- Faculty associate, Princeton Program in Law and Public Affairs 2014- Faculty affiliate, Cognitive Science 2015- Professor, Princeton Neuroscience Institute and Department of Molecular Biology, Princeton University 2015- Faculty affiliate, Program -
View of High Frequency Alternating Currents for Inducing Nerve Block
REDUCTION OF THE ONSET RESPONSE IN HIGH FREQUENCY NERVE BLOCK by DOUGLAS MICHAEL ACKERMANN, JR. Submitted in partial fulfillment of the requirements For the degree of Doctor of Philosophy Dissertation Adviser: Niloy Bhadra, M.D., Ph.D. Department of Biomedical Engineering CASE WESTERN RESERVE UNIVERSITY January, 2010 TITLE PAGE CASE WESTERN RESERVE UNIVERSITY SCHOOL OF GRADUATE STUDIES We hereby approve the thesis/dissertation of Douglas Michael Ackermann, Jr. candidate for the Ph.D. degree *. (signed) ______________P. Hunter Peckham______________ (chair of the committee) _______________Kevin L. Kilgore_______________ ______________Cameron McIntyre______________ _________________Niloy Bhadra_________________ ___________________Joe Payer___________________ (date) _____November 23, 2009_____ *We also certify that written approval has been obtained for any proprietary material contained therein. COMMITTEE SIGNATURE PAGE DEDICATION I would like to dedicate this dissertation to my wonderful family, friends and colleagues who make life so much fun. TABLE OF CONTENTS TABLE OF CONTENTS ..................................................................................................... i LIST OF TABLES .............................................................................................................. v LIST OF FIGURES ........................................................................................................... vi ACKNOWLEDGEMENTS ............................................................................................ -
An Intra-Neural Microstimulation System for Ultra-High Field Magnetic Resonance Imaging and Magnetoencephalography Paul Glover, Roger H
An intra-neural microstimulation system for ultra-high field magnetic resonance imaging and magnetoencephalography Paul Glover, Roger H. Watkins, George C. O’neill, Rochelle Ackerley, Rosa Sanchez-Panchuelo, Matthew J. Brookes, Johan Wessberg, Susan T. Francis, Francis Mcglone To cite this version: Paul Glover, Roger H. Watkins, George C. O’neill, Rochelle Ackerley, Rosa Sanchez-Panchuelo, et al.. An intra-neural microstimulation system for ultra-high field magnetic resonance imaging and magnetoencephalography. Journal of Neuroscience Methods, Elsevier, 2017, 290, pp.69 - 78. 10.1016/j.jneumeth.2017.07.016. hal-01599604 HAL Id: hal-01599604 https://hal.archives-ouvertes.fr/hal-01599604 Submitted on 2 Oct 2017 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. Journal of Neuroscience Methods 290 (2017) 69–78 Contents lists available at ScienceDirect Journal of Neuroscience Methods jo urnal homepage: www.elsevier.com/locate/jneumeth Research Paper An intra-neural microstimulation system for ultra-high field magnetic resonance imaging and magnetoencephalography a,∗ b a b,c Paul M. Glover , Roger H. Watkins , George C. O’Neill , Rochelle Ackerley , a d,e a b Rosa Sanchez-Panchuelo , Francis McGlone , Matthew J. -
WCBR Program 04
Welcome to the Thirty-Seventh Annual Winter Conference on Brain Research The Winter Conference on Brain Research (WCBR) was founded in 1968 to promote free exchange of information and ideas within neuroscience. It was the intent of the founders that both formal and informal interactions would occur between clinical and laboratory-based neuroscientists. During the past thirty years neuroscience has grown and expanded to include many new fields and methodologies. This diversity is also reflected by WCBR participants and in our program. A primary goal of the WCBR is to enable participants to learn about the current status of areas of neuroscience other than their own. Another objective is to provide a vehicle for scientists with common interests to discuss current issues in an informal setting. On the other hand, WCBR is not designed for presentations limited to communicating the latest data to a small group of specialists; this is best done at national society meetings. The program includes panels (reviews for an audience not neces- sarily familiar with the area presented), workshops (informal discussions of current issues and data), and a number of posters. The annual conference lecture will be presented at the Sunday breakfast on January 25. Our guest speaker will be The Honorable John Edward Porter, former Congressman from Illinois and Chair of the House Appropriations Committee. The title of his talk will be What’s Going on in Washington: We Need to Talk! On Tuesday, January 27, a town meeting will be held for the Copper Mountain community, at which Dr. Michael Zigmond, Director of the Morris K.